MCID: SKN022
MIFTS: 50

Skin Squamous Cell Carcinoma malady

Skin diseases, Cancer diseases categories

Summaries for Skin Squamous Cell Carcinoma

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Disease Ontology:10 A skin carcinoma that has material basis in squamous cells.

MalaCards based summary: Skin Squamous Cell Carcinoma, also known as squamous cell carcinoma of skin, is related to medulloblastoma and melanoma. An important gene associated with Skin Squamous Cell Carcinoma is SHFM1 (split hand/foot malformation (ectrodactyly) type 1), and among its related pathways are Alpha6-Beta4 Integrin Signaling Pathway and TP53 network. The compounds manumycin and z-vad-fmk have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and monocytes, and related mouse phenotypes are no phenotypic analysis and vision/eye.

Aliases & Classifications for Skin Squamous Cell Carcinoma

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Skin Squamous Cell Carcinoma, Aliases & Descriptions:

Name: Skin Squamous Cell Carcinoma 10
Squamous Cell Carcinoma of Skin 62
 
Epidermoid Skin Carcinoma 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases


External Ids:

Disease Ontology10 DOID:3151
SNOMED-CT57 254651007
NCIt40 C4819

Related Diseases for Skin Squamous Cell Carcinoma

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Diseases related to Skin Squamous Cell Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 63)
idRelated DiseaseScoreTop Affiliating Genes
1medulloblastoma30.3TP53, PARP1, CASP3
2melanoma30.0STAT2, IL10, TXN, TP63, TP53, PARP1
3epidermodysplasia verruciformis10.4
4pseudovascular skin squamous cell carcinoma10.4
5spindle cell carcinoma10.2
6anal margin squamous cell carcinoma10.2
7cellulitis10.2
8keratoacanthoma10.2
9papilloma10.2
10ewing sarcoma10.0CASP3, NET1
11myeloid leukemia10.0PARP1, STAT2, CASP3
12bronchiolo-alveolar adenocarcinoma10.0CDH1, EIF4E
13esophageal cancer10.0CDH1, TP53
14oral lichen planus10.0CASP3, TP63
15precursor t-cell acute lymphoblastic leukemia10.0CASP3, PARP1, TXN
16nasopharynx carcinoma10.0CDH1, TP53
17actinic keratosis10.0TP63, TP53
18gastric adenocarcinoma10.0CASP3, KLF4, CDH1
19tongue squamous cell carcinoma10.0CDH1, EGF, EIF4E
20stomach cancer10.0CDH1, TP53
21squamous cell carcinoma, head and neck10.0TP53, EIF4E, EGF
22ataxia-telangiectasia10.0CASP3, TP53, PARP1
23breast cancer10.0CDH1, TP53
24lung cancer10.0PARP1, CDH1, TP53
25adenomatous polyposis coli10.0TP53, KLF4, CDH1
26ductal carcinoma in situ10.0TP53, CDH1
27cholangiocarcinoma10.0CDH1, EIF4E, TP53
28bladder transitional cell carcinoma10.0CDH1, TP53, CASP3
29cervical squamous cell carcinoma10.0TP63, EGF
30relapsing-remitting multiple sclerosis10.0IL10, IFNA1
31mesothelioma, somatic10.0TXN, TP63, CDH1
32pancreatic cancer10.0CASP3, CDH1, EGF
33tubular adenocarcinoma10.0TP63, CDH1
34glioblastoma multiforme10.0TP53, PARP1, EIF4E, EGF
35b-cell lymphomas10.0TXN, PARP1, CASP3, TP53
36brain cancer10.0CASP3, EGF, TP53, EIF4E
37vascular disease10.0CASP3, IL10, TXN, TP53
38burkitt lymphoma10.0CASP3, IFNA1, PARP1
39malignant glioma10.0TP53, EGF, CASP3, PARP1
40hepatitis c10.0IL10, IFNA1, TXN
41oral cancer10.0CDH1, TP53, PARP1, CASP3
42nasopharyngeal carcinoma10.0TP53, PARP1, CASP3, CDH1
43transitional cell carcinoma10.0TP53, CDH1, TP63
44breast ductal carcinoma10.0TP53, CDH1
45thyroid cancer, anaplastic10.0CASP3, TP53, EGF, CDH1
46colon adenocarcinoma10.0EIF4E, CASP3, PARP1, CDH1, EGF
47renal cell carcinoma10.0TP53, CDH1, IFNA1
48laryngeal squamous cell carcinoma10.0TP63, TP53, CDH1, EIF4E
49retinoblastoma10.0PARP1, CEBPA, CASP3, EGF, TP53
50endometrial cancer10.0EGF, CDH1, TP53

Graphical network of the top 20 diseases related to Skin Squamous Cell Carcinoma:



Diseases related to skin squamous cell carcinoma

Symptoms for Skin Squamous Cell Carcinoma

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Drugs & Therapeutics for Skin Squamous Cell Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Skin Squamous Cell Carcinoma

Search NIH Clinical Center for Skin Squamous Cell Carcinoma

Genetic Tests for Skin Squamous Cell Carcinoma

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Anatomical Context for Skin Squamous Cell Carcinoma

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MalaCards organs/tissues related to Skin Squamous Cell Carcinoma:

33
Skin, Lung, Monocytes

Animal Models for Skin Squamous Cell Carcinoma or affiliated genes

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Publications for Skin Squamous Cell Carcinoma

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Articles related to Skin Squamous Cell Carcinoma:

(show all 44)
idTitleAuthorsYear
1
Inhibitory effect of curcumin on invasion of skin squamous cell carcinoma a431 cells. (25854367)
2015
2
Skin squamous cell carcinoma presenting as cellulitis. (25635168)
2015
3
Advanced skin squamous cell carcinoma: role of radiotherapy. (24563891)
2014
4
Clinical significance of methylation of E-cadherin and p14ARF gene promoters in skin squamous cell carcinoma tissues. (25126184)
2014
5
Lung transplant recipients receiving voriconazole and skin squamous cell carcinoma risk in Australia. (25358582)
2014
6
Lgr5-positive cells are cancer stem cells in skin squamous cell carcinoma. (25135431)
2014
7
Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma. (25061226)
2014
8
Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. (24917395)
2014
9
HPV type 16-induced skin squamous cell carcinoma located on the groin of immunocompetent patients. (24116660)
2013
10
The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice. (23428654)
2013
11
Immunohistochemical analysis of O(6)-methylguanine-DNA methyltransferase in human melanoma in comparison with skin squamous cell carcinoma. (23460078)
2013
12
Expression and function of NET-1 in human skin squamous cell carcinoma. (24196235)
2013
13
Tetraspanin CD151 plays a key role in skin squamous cell carcinoma. (22824799)
2013
14
Pronounced allelic imbalance at D9S162 in skin squamous cell carcinoma of organ transplant recipients. (22508773)
2012
15
Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness. (23188079)
2012
16
Upregulation of TCTP expression in human skin squamous cell carcinoma increases tumor cell viability through anti-apoptotic action of the protein. (22969908)
2012
17
Curcumin inhibits skin squamous cell carcinoma tumor growth in vivo. (21493306)
2011
18
C/EBPI+ expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPI+ confers susceptibility to UVB-induced skin squamous cell carcinomas. (21346772)
2011
19
The incidence of skin squamous cell carcinoma in Osijek-Baranja County--an epidemiological study. (22220409)
2011
20
Involvement of VILIP-1 (visinin-like protein) and opposite roles of cyclic AMP and GMP signaling in in vitro cell migration of murine skin squamous cell carcinoma. (21480386)
2011
21
Association of the DSS1 c.143G>A polymorphism with skin squamous cell carcinoma. (20220765)
2010
22
Immune phenotype of peripheral blood cells and skin squamous cell carcinoma in organ transplant recipients. (20441422)
2010
23
Expression, clinical and pathological significance of KIAA1173 gene in skin squamous cell carcinoma]. (20646595)
2010
24
Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy. (19077103)
2009
25
The preventive effect of calcitriol on skin squamous cell carcinoma may be due to its effect on prostaglandin E2 metabolism and biologic activity. (20021988)
2009
26
Functions of NET-1 gene in skin squamous cell carcinoma cell line (A431): a siRNA study]. (20078975)
2009
27
Desipramine inhibits the growth of a mouse skin squamous cell carcinoma cell line and affects glucocorticoid receptor-mediated transcription. (19575421)
2009
28
Thioredoxin upregulation by 5-aminolaevulinic acid-based photodynamic therapy in human skin squamous cell carcinoma cell line. (18477133)
2008
29
Downregulation of tazarotene induced gene-2 (TIG2) in skin squamous cell carcinoma. (18955196)
2008
30
Nuclear KrA1ppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis. (18376139)
2008
31
Significance of eIF4E expression in skin squamous cell carcinoma. (17689990)
2007
32
Randomized trial of adjuvant 13-cis-retinoic acid and interferon alfa for patients with aggressive skin squamous cell carcinoma. (17513803)
2007
33
Dominant negative signal transducer and activator of transcription 2 (STAT2) protein: stable expression blocks interferon alpha action in skin squamous cell carcinoma cells. (12748307)
2003
34
Interleukin-10 promoter polymorphisms and susceptibility to skin squamous cell carcinoma after renal transplantation. (12535204)
2003
35
Opposite effect of stable transfection of bioactive transforming growth factor-beta 1 (TGF beta 1) versus exogenous TGF beta 1 treatment on expression of 92-kDa type IV collagenase in mouse skin squamous cell carcinoma CH72 cells. (9210959)
1997
36
Multiple metachronous skin squamous cell carcinomas and epidermodysplasia verruciformis in the head region: a human papilloma virus-associated disease. (7848644)
1994
37
The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event. (7689080)
1993
38
Establishment of highly metastatic tumor clones derived from a skin squamous cell carcinoma (SqC-NH), D-1 and F-3, with distinct features of pulmonary metastases. (8319380)
1993
39
Autocrine secretion of an EGF-like substance by a cell line (HSC-1) derived from a human skin squamous cell carcinoma. (1878344)
1991
40
Analysis of cellular DNA content using flow cytometry in skin squamous cell carcinoma and its relationship to clinical behaviors. (1664278)
1991
41
Jumping translocation of chromosome 14 in a skin squamous cell carcinoma from a xeroderma pigmentosum patient. (3164238)
1988
42
Monocyte Fc-IgG receptors expression and soluble suppressor factor in skin squamous cell carcinoma. (6198840)
1983
43
Metastatic potential of biologic variants of skin squamous cell carcinoma. (7130943)
1982
44
Establishment of a cell line of human skin squamous cell carcinoma in vitro. (7284243)
1981

Variations for Skin Squamous Cell Carcinoma

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Cosmic variations for Skin Squamous Cell Carcinoma:

8
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
143862TP53skin,NS,carcinoma,squamous cell carcinoma4
244225TP53skin,NS,carcinoma,squamous cell carcinoma4
343695TP53skin,NS,carcinoma,squamous cell carcinoma4
410801TP53skin,NS,carcinoma,squamous cell carcinoma4
510988TP53skin,NS,carcinoma,squamous cell carcinoma4
645030TP53skin,NS,carcinoma,squamous cell carcinoma4
743606TP53skin,NS,carcinoma,squamous cell carcinoma4
86549TP53skin,NS,carcinoma,squamous cell carcinoma4
943689TP53skin,NS,carcinoma,squamous cell carcinoma4
1045837TP53skin,NS,carcinoma,squamous cell carcinoma4
1143582TP53skin,NS,carcinoma,squamous cell carcinoma4
1243865TP53skin,NS,carcinoma,squamous cell carcinoma4
1310991TP53skin,NS,carcinoma,squamous cell carcinoma4
1443583TP53skin,NS,carcinoma,squamous cell carcinoma4
1544424TP53skin,NS,carcinoma,squamous cell carcinoma4
1611152TP53skin,NS,carcinoma,squamous cell carcinoma4
1710863TP53skin,NS,carcinoma,squamous cell carcinoma4
1811196TP53skin,NS,carcinoma,squamous cell carcinoma4
1910768TP53skin,NS,carcinoma,squamous cell carcinoma4
2010656TP53skin,NS,carcinoma,squamous cell carcinoma4
2143826TP53skin,NS,carcinoma,squamous cell carcinoma4
2243864TP53skin,NS,carcinoma,squamous cell carcinoma4
236545TP53skin,NS,carcinoma,squamous cell carcinoma4
2410670TP53skin,NS,carcinoma,squamous cell carcinoma4
2545505TP53skin,NS,carcinoma,squamous cell carcinoma4
2643737TP53skin,NS,carcinoma,squamous cell carcinoma4
2710941TP53skin,NS,carcinoma,squamous cell carcinoma4
2810739TP53skin,NS,carcinoma,squamous cell carcinoma4
2944338TP53skin,NS,carcinoma,squamous cell carcinoma4
3044101TP53skin,NS,carcinoma,squamous cell carcinoma4
31496HRASskin,NS,carcinoma,squamous cell carcinoma4
32480HRASskin,NS,carcinoma,squamous cell carcinoma4
33484HRASskin,NS,carcinoma,squamous cell carcinoma4
34481HRASskin,NS,carcinoma,squamous cell carcinoma4
35498HRASskin,NS,carcinoma,squamous cell carcinoma4
36489HRASskin,NS,carcinoma,squamous cell carcinoma4
37483HRASskin,NS,carcinoma,squamous cell carcinoma4
3813220CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
3913224CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
40255155CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4112489CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4212476CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4387425CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4421336EGFRskin,NS,carcinoma,squamous cell carcinoma4
4534166EGFRskin,NS,carcinoma,squamous cell carcinoma4
4617570EGFRskin,NS,carcinoma,squamous cell carcinoma4
47517KRASskin,NS,carcinoma,squamous cell carcinoma4
48763PIK3CAskin,NS,carcinoma,squamous cell carcinoma4

Expression for genes affiliated with Skin Squamous Cell Carcinoma

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Search GEO for disease gene expression data for Skin Squamous Cell Carcinoma.

Pathways for genes affiliated with Skin Squamous Cell Carcinoma

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Pathways related to Skin Squamous Cell Carcinoma according to GeneCards/GeneDecks:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8EIF4E, CASP3, CD151
2
Show member pathways
9.8TP63, TP53
3
Show member pathways
ErbB receptor signaling network38
ErbB signaling pathway38
9.6STAT2, EGF, TP53
49.6CASP3, EIF4E, TP53
5
Show member pathways
9.6TP53, CASP3, EIF4E
6
Show member pathways
9.6CASP3, PARP1, TP53
7
Show member pathways
9.6EGF, CASP3, TP53
89.5CDH1, CASP3, TP53
9
Show member pathways
Apoptosis Modulation and Signaling38
Apoptosis38
9.5TP53, TP63, CASP3
10
Show member pathways
Type III interferon signaling38
9.4STAT2, IFNA1, IL10
11
Show member pathways
Proteasome Degradation38
Immune response Antigen presentation by MHC class I60
9.3TP53, CDH1, SHFM1, CASP3
12
Show member pathways
9.3EGF, NET1, CASP3
139.2CASP3, EGF, TP53, CDH1
149.2EGF, CASP3, CDH1, TP53
159.1CASP3, PARP1, TXN
169.1TXN, CEBPA, IL10
17
Show member pathways
9.1CASP3, TP53, STAT2, IFNA1
189.1TP53, STAT2, IFNA1, EGF
199.1EIF4E, IFNA1, TP53, EGF
209.0KLF4, CDH1, TP53, PARP1
21
Show member pathways
Signal transduction PTEN pathway60
9.0TP53, CEBPA, CASP3, CDH1, EGF
229.0CDH1, EGF, CEBPA, TP53, CASP3
23
Show member pathways
8.9TP53, CASP3, CDH1, NET1
248.9STAT2, IFNA1, EIF4E, NET1
25
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
8.8CASP3, IL10, IFNA1, STAT2, TP53
26
Show member pathways
8.7CASP3, EIF4E, EGF, NET1, TP53
27
Show member pathways
8.6STAT2, CEBPA, TP53, IL10, CASP3, EIF4E
28
Show member pathways
8.5CEBPA, IFNA1, EGF, CASP3, IL10, TP53
29
Show member pathways
8.1IL10, STAT2, TP53, CASP3, CDH1, EGF
30
Show member pathways
7.6TP53, IL10, IFNA1, STAT2, NET1, CDH1

Compounds for genes affiliated with Skin Squamous Cell Carcinoma

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Compounds related to Skin Squamous Cell Carcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 129)
idCompoundScoreTop Affiliating Genes
1manumycin459.9EGF, PARP1, CASP3
2z-vad-fmk45 6110.9CASP3, PARP1, TP53
3p113459.9IFNA1, STAT2
4sulindac sulfide459.8EGF, CASP3, TP53
5indole-3-carbinol459.7PARP1, TP53, CASP3, CDH1
6cd 437459.6PARP1, TP53, CASP3
7temozolomide45 1310.6IFNA1, PARP1, TP53
8triptolide459.6TP53, PARP1, CASP3
9geldanamycin45 51 61 1312.6PARP1, CDH1, EGF, TP53
10ifn-alpha459.6EIF4E, IL10, STAT2, IFNA1
11noxa459.6CASP3, TP63, TP53
12bcnu459.5PARP1, TP53, IFNA1
13gemcitabine45 51 1311.4EGF, TP53, PARP1, IL10, CASP3
14egcg459.4TP53, EGF, CDH1, CASP3, PARP1
15paclitaxel45 51 1311.3CDH1, CASP3, PARP1, TP53, EGF
16thymidylate459.2IL10, IFNA1, TP53, CDH1
17camptothecin45 61 1311.2PARP1, TP53, CASP3, IFNA1
184-hydroxynonenal45 2610.2TXN, CASP3, PARP1, IL10
19mg 13245 6110.2EGF, CDH1, CASP3, PARP1, TP53, EIF4E
20irinotecan45 51 1311.1TP53, PARP1, EGF, IFNA1, CDH1
215fluorouracil459.1CDH1, EGF, CASP3, IFNA1, TP53
22genistein45 30 61 3 26 1314.0CASP3, STAT2, PARP1, EGF, CDH1
23butyrate459.0TP53, CASP3, KLF4, EGF, CDH1
242-chlorodeoxyadenosine459.0PARP1, TP53, IFNA1
25pd 98,059459.0PARP1, CDH1, CASP3, KLF4, EGF, EIF4E
26resveratrol45 61 26 1312.0PARP1, CASP3, TP53, TXN
27mitomycin c458.9IL10, TP53, TP63, TXN
28rapamycin458.9IFNA1, CDH1, CASP3, EIF4E, IL10, EGF
29suberoylanilide hydroxamic acid458.9TXN, TP53, PARP1, CASP3, CDH1
30sb 20358045 619.9EGF, CDH1, CASP3, IL10, PARP1, TP53
31ly294002458.9EIF4E, IL10, PARP1, TP53, CASP3, CDH1
32hydroxyurea45 51 1310.8TXN, TP53, IFNA1, IL10
33n acetylcysteine458.6TXN, EIF4E, CDH1, CASP3, PARP1, TP53
34adriamycin458.6CDH1, CASP3, TP53, TXN, IFNA1
35h2o2458.5PARP1, TXN, CASP3, EGF, EIF4E, TP53
36thymidine45 269.5KLF4, IFNA1, EGF, IL10, TP63, TP53
37arsenite45 269.4CASP3, IFNA1, TXN, EIF4E, PARP1, TP53
38docetaxel45 51 61 1311.3TXN, PARP1, IFNA1, CDH1, CASP3, TP53
39retinoid458.3CDH1, RARRES2, IFNA1, TXN, TP53
40estrogen458.2TP53, EGF, TXN, CEBPA, CDH1, EIF4E
41actinomycin d458.1TP53, CASP3, EIF4E, TXN, IFNA1, PARP1
42dexamethasone45 51 30 1311.1EGF, PARP1, CEBPA, CDH1, IL10, TXN
43etoposide45 51 61 1311.1CDH1, EIF4E, CASP3, IFNA1, PARP1, TP53
44cysteine458.0RARRES2, CASP3, CDH1, CD151, EIF4E, PARP1
45cycloheximide457.8CASP3, IFNA1, EIF4E, PARP1, EGF, TXN
46doxorubicin45 51 139.7TP63, PARP1, IFNA1, CASP3, CDH1, TP53
47cisplatin45 51 61 1310.5EIF4E, TXN, TP63, TP53, PARP1, IFNA1
48serine457.4STAT2, EIF4E, RARRES2, CASP3, IFNA1, TXN
49vegf457.2EIF4E, CASP3, IL10, IFNA1, TP53, TP63
50retinoic acid45 267.6EGF, CDH1, EIF4E, RARRES2, CASP3, IFNA1

GO Terms for genes affiliated with Skin Squamous Cell Carcinoma

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Cellular components related to Skin Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear chromatinGO:00007909.2TP63, TP53, KLF4
2nucleoplasmGO:00056548.1TXN, TP63, TP53, PARP1, STAT2, CASP3
3cytosolGO:00058297.1TP53, TP63, NET1, STAT2, CASP3, EIF4E

Biological processes related to Skin Squamous Cell Carcinoma according to GeneCards/GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1macrophage differentiationGO:003022510.2PARP1, CEBPA
2regulation of protein localization to cell surfaceGO:0200000810.1EGF, CDH1
3regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:004328110.1CDH1, CASP3
4negative regulation of B cell proliferationGO:003088910.1CASP3, IL10
5cellular response to lithium ionGO:007128510.1CDH1, CEBPA
6mitotic G1 DNA damage checkpointGO:003157110.0TP63, TP53
7DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697810.0TP63, TP53
8response to X-rayGO:00101659.9TP63, TP53
9neuron apoptotic processGO:00514029.8CASP3, TP53, TP63
10release of cytochrome c from mitochondriaGO:00018369.7CASP3, TP53
11cellular response to ionizing radiationGO:00714799.5NET1, TP53
12cell agingGO:00075699.5TP53, TP63
13positive regulation of DNA bindingGO:00433889.4EGF, TXN
14negative regulation of apoptotic processGO:00430669.2TP63, TP53, IL10, CASP3
15positive regulation of transcription from RNA polymerase II promoterGO:00459448.7TP63, TP53, PARP1, CEBPA, IL10, KLF4
16positive regulation of transcription, DNA-templatedGO:00458938.6EGF, CDH1, KLF4, IL10, TP53, TP63
17negative regulation of transcription from RNA polymerase II promoterGO:00001228.2TXN, TP63, TP53, PARP1, CEBPA, KLF4

Molecular functions related to Skin Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionGO:00010779.1TP53, TP63, KLF4
2transcription regulatory region DNA bindingGO:00442129.0KLF4, CEBPA, TP53, TP63
3identical protein bindingGO:00428029.0STAT2, TP53, TP63, PARP1
4sequence-specific DNA binding transcription factor activityGO:00037008.8STAT2, CEBPA, KLF4, TP53, TP63
5protein bindingGO:00055155.8STAT2, PARP1, CASP3, RARRES2, KLF4, EIF4E

Products for genes affiliated with Skin Squamous Cell Carcinoma

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4CDC
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24GTR
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26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
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37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
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52PubMed
53QIAGEN
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