MCID: SKN022
MIFTS: 43

Skin Squamous Cell Carcinoma malady

Skin diseases, Cancer diseases categories

Aliases & Classifications for Skin Squamous Cell Carcinoma

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Skin Squamous Cell Carcinoma, Aliases & Descriptions:

Name: Skin Squamous Cell Carcinoma 9
Squamous Cell Carcinoma of Skin 60
 
Epidermoid Skin Carcinoma 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases


External Ids:

Disease Ontology9 DOID:3151
SNOMED-CT55 254651007
NCIt38 C4819

Summaries for Skin Squamous Cell Carcinoma

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Disease Ontology:9 A skin carcinoma that has material basis in squamous cells.

MalaCards based summary: Skin Squamous Cell Carcinoma, also known as squamous cell carcinoma of skin, is related to medulloblastoma and melanoma. An important gene associated with Skin Squamous Cell Carcinoma is SHFM1 (split hand/foot malformation (ectrodactyly) type 1), and among its related pathways are Alpha6-Beta4 Integrin Signaling Pathway and TP53 network. The compounds manumycin and z-vad-fmk have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and monocytes, and related mouse phenotypes are no phenotypic analysis and vision/eye.

Related Diseases for Skin Squamous Cell Carcinoma

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Diseases related to Skin Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idRelated DiseaseScoreTop Affiliating Genes
1medulloblastoma30.3CASP3, PARP1, TP53
2melanoma28.2CDH1, TXN, TP63, TP53, PARP1, STAT2
3pseudovascular skin squamous cell carcinoma10.4
4epidermodysplasia verruciformis10.4
5ewing sarcoma10.2NET1, CASP3
6myeloid leukemia10.2CASP3, STAT2, PARP1
7spindle cell carcinoma10.2
8anal margin squamous cell carcinoma10.2
9cellulitis10.2
10keratoacanthoma10.2
11papilloma10.2
12bronchiolo-alveolar adenocarcinoma10.2CDH1, EIF4E
13esophageal cancer10.2TP53, CDH1
14oral lichen planus10.1CASP3, TP63
15precursor t-cell acute lymphoblastic leukemia10.1CASP3, PARP1, TXN
16nasopharynx carcinoma10.1CDH1, TP53
17actinic keratosis10.1TP53, TP63
18gastric adenocarcinoma10.1CASP3, KLF4, CDH1
19tongue squamous cell carcinoma10.1EGF, CDH1, EIF4E
20stomach cancer10.1CDH1, TP53
21squamous cell carcinoma, head and neck10.1TP53, EIF4E, EGF
22ataxia-telangiectasia10.1TP53, PARP1, CASP3
23breast cancer10.1CDH1, TP53
24lung cancer10.0TP53, PARP1, CDH1
25adenomatous polyposis coli10.0TP53, KLF4, CDH1
26ductal carcinoma in situ10.0TP53, CDH1
27cholangiocarcinoma10.0TP53, EIF4E, CDH1
28bladder transitional cell carcinoma10.0TP53, CASP3, CDH1
29cervical squamous cell carcinoma10.0EGF, TP63
30relapsing-remitting multiple sclerosis10.0IL10, IFNA1
31mesothelioma, somatic10.0TXN, TP63, CDH1
32pancreatic cancer10.0CASP3, CDH1, EGF
33tubular adenocarcinoma10.0CDH1, TP63
34glioblastoma multiforme10.0EGF, EIF4E, PARP1, TP53
35b-cell lymphomas9.9CASP3, PARP1, TP53, TXN
36brain cancer9.9EGF, EIF4E, CASP3, TP53
37vascular disease9.9CASP3, IL10, TP53, TXN
38burkitt lymphoma9.9PARP1, IFNA1, CASP3
39malignant glioma9.9TP53, PARP1, CASP3, EGF
40hepatitis c9.9TXN, IFNA1, IL10
41oral cancer9.9CDH1, CASP3, PARP1, TP53
42nasopharyngeal carcinoma9.9TP53, PARP1, CASP3, CDH1
43transitional cell carcinoma9.9CDH1, TP53, TP63
44breast ductal carcinoma9.9CDH1, TP53
45thyroid cancer, anaplastic9.9TP53, CASP3, CDH1, EGF
46colon adenocarcinoma9.8PARP1, CASP3, EIF4E, CDH1, EGF
47renal cell carcinoma9.8TP53, IFNA1, CDH1
48laryngeal squamous cell carcinoma9.8TP63, TP53, EIF4E, CDH1
49retinoblastoma9.8TP53, PARP1, CEBPA, CASP3, EGF
50endometrial cancer9.8TP53, CDH1, EGF

Graphical network of the top 20 diseases related to Skin Squamous Cell Carcinoma:



Diseases related to skin squamous cell carcinoma

Symptoms for Skin Squamous Cell Carcinoma

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Drugs & Therapeutics for Skin Squamous Cell Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Skin Squamous Cell Carcinoma

Search NIH Clinical Center for Skin Squamous Cell Carcinoma

Genetic Tests for Skin Squamous Cell Carcinoma

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Anatomical Context for Skin Squamous Cell Carcinoma

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MalaCards organs/tissues related to Skin Squamous Cell Carcinoma:

31
Skin, Lung, Monocytes

Animal Models for Skin Squamous Cell Carcinoma or affiliated genes

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Publications for Skin Squamous Cell Carcinoma

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Articles related to Skin Squamous Cell Carcinoma:

(show all 44)
idTitleAuthorsYear
1
Inhibitory effect of curcumin on invasion of skin squamous cell carcinoma a431 cells. (25854367)
2015
2
Skin squamous cell carcinoma presenting as cellulitis. (25635168)
2015
3
Advanced skin squamous cell carcinoma: role of radiotherapy. (24563891)
2014
4
Clinical significance of methylation of E-cadherin and p14ARF gene promoters in skin squamous cell carcinoma tissues. (25126184)
2014
5
Lung transplant recipients receiving voriconazole and skin squamous cell carcinoma risk in Australia. (25358582)
2014
6
Lgr5-positive cells are cancer stem cells in skin squamous cell carcinoma. (25135431)
2014
7
Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma. (25061226)
2014
8
Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. (24917395)
2014
9
HPV type 16-induced skin squamous cell carcinoma located on the groin of immunocompetent patients. (24116660)
2013
10
The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice. (23428654)
2013
11
Immunohistochemical analysis of O(6)-methylguanine-DNA methyltransferase in human melanoma in comparison with skin squamous cell carcinoma. (23460078)
2013
12
Expression and function of NET-1 in human skin squamous cell carcinoma. (24196235)
2013
13
Tetraspanin CD151 plays a key role in skin squamous cell carcinoma. (22824799)
2013
14
Pronounced allelic imbalance at D9S162 in skin squamous cell carcinoma of organ transplant recipients. (22508773)
2012
15
Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness. (23188079)
2012
16
Upregulation of TCTP expression in human skin squamous cell carcinoma increases tumor cell viability through anti-apoptotic action of the protein. (22969908)
2012
17
Curcumin inhibits skin squamous cell carcinoma tumor growth in vivo. (21493306)
2011
18
C/EBPI+ expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPI+ confers susceptibility to UVB-induced skin squamous cell carcinomas. (21346772)
2011
19
The incidence of skin squamous cell carcinoma in Osijek-Baranja County--an epidemiological study. (22220409)
2011
20
Involvement of VILIP-1 (visinin-like protein) and opposite roles of cyclic AMP and GMP signaling in in vitro cell migration of murine skin squamous cell carcinoma. (21480386)
2011
21
Association of the DSS1 c.143G>A polymorphism with skin squamous cell carcinoma. (20220765)
2010
22
Immune phenotype of peripheral blood cells and skin squamous cell carcinoma in organ transplant recipients. (20441422)
2010
23
Expression, clinical and pathological significance of KIAA1173 gene in skin squamous cell carcinoma]. (20646595)
2010
24
Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy. (19077103)
2009
25
The preventive effect of calcitriol on skin squamous cell carcinoma may be due to its effect on prostaglandin E2 metabolism and biologic activity. (20021988)
2009
26
Functions of NET-1 gene in skin squamous cell carcinoma cell line (A431): a siRNA study]. (20078975)
2009
27
Desipramine inhibits the growth of a mouse skin squamous cell carcinoma cell line and affects glucocorticoid receptor-mediated transcription. (19575421)
2009
28
Thioredoxin upregulation by 5-aminolaevulinic acid-based photodynamic therapy in human skin squamous cell carcinoma cell line. (18477133)
2008
29
Downregulation of tazarotene induced gene-2 (TIG2) in skin squamous cell carcinoma. (18955196)
2008
30
Nuclear KrA1ppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis. (18376139)
2008
31
Significance of eIF4E expression in skin squamous cell carcinoma. (17689990)
2007
32
Randomized trial of adjuvant 13-cis-retinoic acid and interferon alfa for patients with aggressive skin squamous cell carcinoma. (17513803)
2007
33
Dominant negative signal transducer and activator of transcription 2 (STAT2) protein: stable expression blocks interferon alpha action in skin squamous cell carcinoma cells. (12748307)
2003
34
Interleukin-10 promoter polymorphisms and susceptibility to skin squamous cell carcinoma after renal transplantation. (12535204)
2003
35
Opposite effect of stable transfection of bioactive transforming growth factor-beta 1 (TGF beta 1) versus exogenous TGF beta 1 treatment on expression of 92-kDa type IV collagenase in mouse skin squamous cell carcinoma CH72 cells. (9210959)
1997
36
Multiple metachronous skin squamous cell carcinomas and epidermodysplasia verruciformis in the head region: a human papilloma virus-associated disease. (7848644)
1994
37
The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event. (7689080)
1993
38
Establishment of highly metastatic tumor clones derived from a skin squamous cell carcinoma (SqC-NH), D-1 and F-3, with distinct features of pulmonary metastases. (8319380)
1993
39
Autocrine secretion of an EGF-like substance by a cell line (HSC-1) derived from a human skin squamous cell carcinoma. (1878344)
1991
40
Analysis of cellular DNA content using flow cytometry in skin squamous cell carcinoma and its relationship to clinical behaviors. (1664278)
1991
41
Jumping translocation of chromosome 14 in a skin squamous cell carcinoma from a xeroderma pigmentosum patient. (3164238)
1988
42
Monocyte Fc-IgG receptors expression and soluble suppressor factor in skin squamous cell carcinoma. (6198840)
1983
43
Metastatic potential of biologic variants of skin squamous cell carcinoma. (7130943)
1982
44
Establishment of a cell line of human skin squamous cell carcinoma in vitro. (7284243)
1981

Variations for Skin Squamous Cell Carcinoma

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Cosmic variations for Skin Squamous Cell Carcinoma:

7 (show all 48)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
143862TP53skin,NS,carcinoma,squamous cell carcinoma4
244225TP53skin,NS,carcinoma,squamous cell carcinoma4
343695TP53skin,NS,carcinoma,squamous cell carcinoma4
410801TP53skin,NS,carcinoma,squamous cell carcinoma4
510988TP53skin,NS,carcinoma,squamous cell carcinoma4
645030TP53skin,NS,carcinoma,squamous cell carcinoma4
743606TP53skin,NS,carcinoma,squamous cell carcinoma4
86549TP53skin,NS,carcinoma,squamous cell carcinoma4
943689TP53skin,NS,carcinoma,squamous cell carcinoma4
1045837TP53skin,NS,carcinoma,squamous cell carcinoma4
1143582TP53skin,NS,carcinoma,squamous cell carcinoma4
1243865TP53skin,NS,carcinoma,squamous cell carcinoma4
1310991TP53skin,NS,carcinoma,squamous cell carcinoma4
1443583TP53skin,NS,carcinoma,squamous cell carcinoma4
1544424TP53skin,NS,carcinoma,squamous cell carcinoma4
1611152TP53skin,NS,carcinoma,squamous cell carcinoma4
1710863TP53skin,NS,carcinoma,squamous cell carcinoma4
1811196TP53skin,NS,carcinoma,squamous cell carcinoma4
1910768TP53skin,NS,carcinoma,squamous cell carcinoma4
2010656TP53skin,NS,carcinoma,squamous cell carcinoma4
2143826TP53skin,NS,carcinoma,squamous cell carcinoma4
2243864TP53skin,NS,carcinoma,squamous cell carcinoma4
236545TP53skin,NS,carcinoma,squamous cell carcinoma4
2410670TP53skin,NS,carcinoma,squamous cell carcinoma4
2545505TP53skin,NS,carcinoma,squamous cell carcinoma4
2643737TP53skin,NS,carcinoma,squamous cell carcinoma4
2710941TP53skin,NS,carcinoma,squamous cell carcinoma4
2810739TP53skin,NS,carcinoma,squamous cell carcinoma4
2944338TP53skin,NS,carcinoma,squamous cell carcinoma4
3044101TP53skin,NS,carcinoma,squamous cell carcinoma4
31496HRASskin,NS,carcinoma,squamous cell carcinoma4
32480HRASskin,NS,carcinoma,squamous cell carcinoma4
33484HRASskin,NS,carcinoma,squamous cell carcinoma4
34481HRASskin,NS,carcinoma,squamous cell carcinoma4
35498HRASskin,NS,carcinoma,squamous cell carcinoma4
36489HRASskin,NS,carcinoma,squamous cell carcinoma4
37483HRASskin,NS,carcinoma,squamous cell carcinoma4
3813220CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
3913224CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
40255155CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4112489CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4212476CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4387425CDKN2Askin,NS,carcinoma,squamous cell carcinoma4
4421336EGFRskin,NS,carcinoma,squamous cell carcinoma4
4534166EGFRskin,NS,carcinoma,squamous cell carcinoma4
4617570EGFRskin,NS,carcinoma,squamous cell carcinoma4
47517KRASskin,NS,carcinoma,squamous cell carcinoma4
48763PIK3CAskin,NS,carcinoma,squamous cell carcinoma4

Expression for genes affiliated with Skin Squamous Cell Carcinoma

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Search GEO for disease gene expression data for Skin Squamous Cell Carcinoma.

Pathways for genes affiliated with Skin Squamous Cell Carcinoma

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Pathways related to Skin Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8CD151, EIF4E, CASP3
2
Show member pathways
9.8TP53, TP63
3
Show member pathways
ErbB receptor signaling network36
ErbB signaling pathway36
9.6TP53, STAT2, EGF
4
Show member pathways
9.6EIF4E, CASP3, TP53
59.6TP53, CASP3, EIF4E
6
Show member pathways
9.6CASP3, PARP1, TP53
7
Show member pathways
9.6TP53, CASP3, EGF
89.5CDH1, CASP3, TP53
9
Show member pathways
Apoptosis Modulation and Signaling36
Apoptosis36
9.5CASP3, TP53, TP63
10
Show member pathways
Type III interferon signaling36
9.4STAT2, IFNA1, IL10
11
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I58
9.3CDH1, CASP3, TP53, SHFM1
12
Show member pathways
9.3NET1, CASP3, EGF
139.2EGF, CDH1, CASP3, TP53
149.2TP53, CASP3, CDH1, EGF
159.1TXN, PARP1, CASP3
169.1IL10, CEBPA, TXN
17
Show member pathways
9.1TP53, STAT2, IFNA1, CASP3
189.1EGF, IFNA1, STAT2, TP53
199.1EGF, EIF4E, IFNA1, TP53
20
Show member pathways
Signal transduction PTEN pathway58
9.0TP53, CEBPA, CASP3, CDH1, EGF
219.0TP53, CEBPA, CASP3, CDH1, EGF
22
Show member pathways
8.9CDH1, CASP3, NET1, TP53
238.9EIF4E, IFNA1, STAT2, NET1
24
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.8TP53, STAT2, IFNA1, IL10, CASP3
25
Show member pathways
8.7TP53, NET1, CASP3, EIF4E, EGF
26
Show member pathways
8.6TP53, CEBPA, STAT2, IL10, CASP3, EIF4E
27
Show member pathways
8.5TP53, CEBPA, IFNA1, IL10, CASP3, EGF
28
Show member pathways
8.1TP53, NET1, STAT2, IL10, CASP3, CDH1
29
Show member pathways
7.6EGF, TP53, NET1, STAT2, IFNA1, IL10

Compounds for genes affiliated with Skin Squamous Cell Carcinoma

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Compounds related to Skin Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 129)
idCompoundScoreTop Affiliating Genes
1manumycin439.9EGF, PARP1, CASP3
2z-vad-fmk43 5910.9CASP3, PARP1, TP53
3p113439.9IFNA1, STAT2
4sulindac sulfide439.8EGF, CASP3, TP53
5indole-3-carbinol439.7PARP1, TP53, CASP3, CDH1
6cd 437439.6PARP1, TP53, CASP3
7temozolomide43 1210.6IFNA1, PARP1, TP53
8triptolide439.6TP53, PARP1, CASP3
9geldanamycin43 49 59 1212.6PARP1, CDH1, EGF, TP53
10ifn-alpha439.6EIF4E, IL10, STAT2, IFNA1
11noxa439.6CASP3, TP63, TP53
12bcnu439.5PARP1, TP53, IFNA1
13gemcitabine43 49 1211.4EGF, TP53, PARP1, IL10, CASP3
14egcg439.4TP53, EGF, CDH1, CASP3, PARP1
15paclitaxel43 49 1211.3CDH1, CASP3, PARP1, TP53, EGF
16thymidylate439.2IL10, IFNA1, TP53, CDH1
17camptothecin43 59 1211.2PARP1, TP53, CASP3, IFNA1
184-hydroxynonenal43 2410.2TXN, CASP3, PARP1, IL10
19mg 13243 5910.2EGF, CDH1, CASP3, PARP1, TP53, EIF4E
20irinotecan43 49 1211.1TP53, PARP1, EGF, IFNA1, CDH1
215fluorouracil439.1CDH1, EGF, CASP3, IFNA1, TP53
22genistein43 28 59 2 24 1214.0CASP3, STAT2, PARP1, EGF, CDH1
23butyrate439.0TP53, CASP3, KLF4, EGF, CDH1
242-chlorodeoxyadenosine439.0PARP1, TP53, IFNA1
25pd 98,059439.0PARP1, CDH1, CASP3, KLF4, EGF, EIF4E
26resveratrol43 59 24 1212.0PARP1, CASP3, TP53, TXN
27mitomycin c438.9IL10, TP53, TP63, TXN
28rapamycin438.9IFNA1, CDH1, CASP3, EIF4E, IL10, EGF
29suberoylanilide hydroxamic acid438.9TXN, TP53, PARP1, CASP3, CDH1
30sb 20358043 599.9EGF, CDH1, CASP3, IL10, PARP1, TP53
31ly294002438.9EIF4E, IL10, PARP1, TP53, CASP3, CDH1
32hydroxyurea43 49 1210.8TXN, TP53, IFNA1, IL10
33n acetylcysteine438.6TXN, EIF4E, CDH1, CASP3, PARP1, TP53
34adriamycin438.6CDH1, CASP3, TP53, TXN, IFNA1
35h2o2438.5PARP1, TXN, CASP3, EGF, EIF4E, TP53
36thymidine43 249.5KLF4, IFNA1, EGF, IL10, TP63, TP53
37arsenite43 249.4CASP3, IFNA1, TXN, EIF4E, PARP1, TP53
38docetaxel43 49 59 1211.3TXN, PARP1, IFNA1, CDH1, CASP3, TP53
39retinoid438.3CDH1, RARRES2, IFNA1, TXN, TP53
40estrogen438.2TP53, EGF, TXN, CEBPA, CDH1, EIF4E
41actinomycin d438.1TP53, CASP3, EIF4E, TXN, IFNA1, PARP1
42dexamethasone43 49 28 1211.1EGF, PARP1, CEBPA, CDH1, IL10, TXN
43etoposide43 49 59 1211.1CDH1, EIF4E, CASP3, IFNA1, PARP1, TP53
44cysteine438.0RARRES2, CASP3, CDH1, CD151, EIF4E, PARP1
45cycloheximide437.8CASP3, IFNA1, EIF4E, PARP1, EGF, TXN
46doxorubicin43 49 129.7TP63, PARP1, IFNA1, CASP3, CDH1, TP53
47cisplatin43 49 59 1210.5EIF4E, TXN, TP63, TP53, PARP1, IFNA1
48serine437.4STAT2, EIF4E, RARRES2, CASP3, IFNA1, TXN
49vegf437.2EIF4E, CASP3, IL10, IFNA1, TP53, TP63
50retinoic acid43 247.6EGF, CDH1, EIF4E, RARRES2, CASP3, IFNA1

GO Terms for genes affiliated with Skin Squamous Cell Carcinoma

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Cellular components related to Skin Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nuclear chromatinGO:00007909.2KLF4, TP53, TP63
2nucleoplasmGO:00056548.1CASP3, TXN, TP63, TP53, PARP1, STAT2
3cytosolGO:00058297.1TXN, TP63, TP53, NET1, STAT2, CASP3

Biological processes related to Skin Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1macrophage differentiationGO:003022510.2PARP1, CEBPA
2regulation of protein localization to cell surfaceGO:0200000810.1EGF, CDH1
3regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:004328110.1CDH1, CASP3
4negative regulation of B cell proliferationGO:003088910.1CASP3, IL10
5cellular response to lithium ionGO:007128510.1CDH1, CEBPA
6mitotic G1 DNA damage checkpointGO:003157110.0TP63, TP53
7DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697810.0TP63, TP53
8response to X-rayGO:00101659.9TP63, TP53
9neuron apoptotic processGO:00514029.8CASP3, TP53, TP63
10release of cytochrome c from mitochondriaGO:00018369.7CASP3, TP53
11cellular response to ionizing radiationGO:00714799.5NET1, TP53
12cell agingGO:00075699.5TP53, TP63
13positive regulation of DNA bindingGO:00433889.4EGF, TXN
14negative regulation of apoptotic processGO:00430669.2TP63, TP53, IL10, CASP3
15positive regulation of transcription from RNA polymerase II promoterGO:00459448.7TP63, TP53, PARP1, CEBPA, IL10, KLF4
16positive regulation of transcription, DNA-templatedGO:00458938.6EGF, CDH1, KLF4, IL10, TP53, TP63
17negative regulation of transcription from RNA polymerase II promoterGO:00001228.2TXN, TP63, TP53, PARP1, CEBPA, KLF4

Molecular functions related to Skin Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionGO:00010779.1KLF4, TP53, TP63
2transcription regulatory region DNA bindingGO:00442129.0TP63, TP53, CEBPA, KLF4
3identical protein bindingGO:00428029.0TP63, TP53, PARP1, STAT2
4sequence-specific DNA binding transcription factor activityGO:00037008.8KLF4, STAT2, CEBPA, TP53, TP63
5protein bindingGO:00055155.8EGF, SHFM1, TXN, TP63, TP53, PARP1

Products for genes affiliated with Skin Squamous Cell Carcinoma

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Sources for Skin Squamous Cell Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet