Aliases & Classifications for Skin Tag

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 38NCIt
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Skin Tag, Aliases & Descriptions:

Name: Skin Tag 9 60
Fibroepithelial Polyp of Skin 9
Fibroepithelial Polyp 9
Cutaneous Tag 9
 
Soft Fibroma 9
Skin Tag Nos 9
Skin Tags 43
Tag 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


External Ids:

Disease Ontology9 DOID:6873
NCIt38 C3374, C3337

Summaries for Skin Tag

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MalaCards based summary: Skin Tag, also known as fibroepithelial polyp of skin, is related to acanthosis nigricans and infertility. An important gene associated with Skin Tag is EFTUD2 (elongation factor Tu GTP binding domain containing 2), and among its related pathways are Adipogenesis and AMPK Enzyme Complex Pathway. The compounds exenatide and pramlintide have been mentioned in the context of this disorder. Affiliated tissues include skin and colon, and related mouse phenotypes are adipose tissue and limbs/digits/tail.

Related Diseases for Skin Tag

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Diseases related to Skin Tag via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1acanthosis nigricans30.6LEP, INS
2infertility29.7INS, LEP, ESR1
3fibroepithelial polyp of urethra10.6
4fibroepithelial polyp of the anus10.6
5vulva fibroepithelial polyp10.6
6rabson-mendenhall syndrome10.4INS
7acquired generalized lipodystrophy10.4LEP
8hemifacial microsomia10.3
9cat eye syndrome10.3
10ovarian disease10.3ESR1
11mandibulofacial dysostosis, guion-almeida type10.3
12fibroma10.3
13cystitis cystica10.2
14ureteral obstruction10.2
15ureterocele10.2
16intussusception10.2
17fibrous histiocytoma10.2
18verrucous carcinoma10.2
19cystitis10.2
20endometriosis10.2
21hemangiopericytoma10.2
22histiocytoma10.2
23ileus10.2
24frontonasal dysplasia 110.2
25auriculocondylar syndrome 110.2
26treacher collins syndrome 110.2
27townes-brocks syndrome10.2
28emanuel syndrome10.2
29lipoma10.2
30deafness, congenital with inner ear agenesis, microtia, and microdontia10.2
31microcephaly10.2
32microphthalmia10.2
33cri-du-chat syndrome10.2
34kaufman oculocerebrofacial syndrome10.2
35lambert syndrome10.2
36microsomia hemifacial radial defects10.2
37oculocerebrocutaneous syndrome10.2
38mental retardation10.2
39familial partial lipodystrophy10.2LEP, INS
40fetal macrosomia10.2LEP, INS
41berardinelli-seip congenital lipodystrophy10.1LEP, INS
42anovulation10.1INS, LEP
43eating disorder10.1LEP, INS
44amenorrhea10.1LEP, INS
45growth hormone deficiency10.1LEP, INS
46morbid obesity10.1LEP, INS
47hypopituitarism10.1LEP, INS
48mody, type ii10.1LEP, INS
49hyperandrogenism10.1INS, LEP
50lipodystrophy10.1LEP, INS

Graphical network of the top 20 diseases related to Skin Tag:



Diseases related to skin tag

Symptoms for Skin Tag

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Drugs & Therapeutics for Skin Tag

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Drug clinical trials:

Search ClinicalTrials for Skin Tag

Search NIH Clinical Center for Skin Tag

Genetic Tests for Skin Tag

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Anatomical Context for Skin Tag

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MalaCards organs/tissues related to Skin Tag:

31
Skin, Colon

Animal Models for Skin Tag or affiliated genes

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Publications for Skin Tag

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Articles related to Skin Tag:

(show all 42)
idTitleAuthorsYear
1
Role of mast cells in skin tag development: an immunohistochemical study. (25291860)
2014
2
An infant with PELVIS (perineal hemangioma, external genital malformations, lipomyelomeningocele, vesicorenal abnormalities, imperforate anus, and skin tag) syndrome misdiagnosed as diaper rash. (24948350)
2014
3
Pai syndrome: median cleft lip, corpus callosum lipoma, and fibroepithelial skin tag. (24741390)
2014
4
Case report of a very large skin tag in an unusual location that grew rapidly during pregnancy. (24611972)
2014
5
Anal atresia, coloboma, microphthalmia, and nasal skin tag in a female patient with 3.5a88Mb deletion of 3q26 encompassing SOX2. (23613260)
2013
6
Association of acanthosis nigricans and skin tags with insulin resistance. (22481657)
2012
7
Skin tag (acrochordon) on labium majus in an infertile female. (22980625)
2012
8
An association of human papillomaviruses low risk and high risk subtypes with skin tag. (23493098)
2012
9
Skin tags and acanthosis nigricans in patients with hepatitis C infection in relation to insulin resistance and insulin like growth factor-1 levels. (22615504)
2012
10
Atypical lipomatous tumor/"well-differentiated liposarcoma" of the skin clinically presenting as a skin tag: clinicopathologic, immunohistochemical, and molecular analysis of 2 cases. (21358383)
2011
11
Skin tags, leptin, metabolic syndrome and change of the life style. (21860156)
2011
12
Skin tag and acanthosis nigricans: do they have a predictive value for gestational diabetes mellitus? (21472660)
2011
13
Increased tissue leptin hormone level and mast cell count in skin tags: a possible role of adipoimmune in the growth of benign skin growths. (20826994)
2010
14
Is there any relation between serum insulin and insulin-like growth factor-I in non-diabetic patients with skin tag? (19453787)
2010
15
A study of androgen and estrogen receptors alpha, beta in skin tags. (20418971)
2010
16
Anal skin tag: do not injure the elephants. (20463592)
2010
17
Mammary skin tag in a 2-year-old girl: a long-lasting adnexal polyp of neonatal skin? (19840327)
2009
18
Verruca plus acrochordon: an 'over the top' skin tag. (19747304)
2009
19
Mandibulofacial syndrome with growth and mental retardation, microcephaly, ear anomalies with skin tags, and cleft palate in a mother and her son: autosomal dominant or X-linked syndrome? (19921636)
2009
20
Serum leptin, atherogenic lipids and glucose levels in patients with skin tags. (20049263)
2009
21
Four limb syndactyly, constriction rings and skin tags; amniotic bands or disorganization-like syndrome. (18978653)
2008
22
Neuronal migration disorders, agenesis of corpus callosum, preauricular skin tag and bilateral morning glory syndrome in a term newborn infant. (18388784)
2008
23
Screening of glucose/insulin metabolic alterations in men with multiple skin tags on the neck. (18397315)
2008
24
Skin tag removal [corrected]. (18791098)
2008
25
Basal cell carcinoma in a skin tag. (18779117)
2008
26
Rhabdomyomatous mesenchymal hamartoma presenting as a skin tag in the sternoclavicular area. (18158576)
2007
27
Skin tag as a cutaneous marker for impaired carbohydrate metabolism: a case-control study. (17988334)
2007
28
Prenatal sonographic diagnosis of congenital perineal skin tag: case report and review of the literature. (16952203)
2006
29
'Myxopapillary' ependymal rest presenting as a pre-sacral skin tag. (15875743)
2005
30
Skin tag. (15604558)
2005
31
Marzouk skin tag two-stage urethroplasty for the repair of complex cases of hypospadias. (14678181)
2004
32
Eccrine nevus presenting as a perianal skin tag: a case report and review of the literature. (12142620)
2002
33
Blister on a skin tag. (12218240)
2002
34
Multiple congenital anomalies syndrome: growth and mental retardation, microcephaly, preauricular skin tags, cleft palate, camptodactyly, and distal limb anomalies. Report on two unrelated Brazilian patients. (10528252)
1999
35
A case of perineal schwannoma resembling a skin tag. (10554437)
1999
36
Hemifacial microsomia in a newborn with hypoplastic skin lesions, an eyelid skin tag, and microphthalmia: an unusual presentation of Delleman syndrome. (9823495)
1998
37
Guess what! Skin tag (acrochordon) on the labium majus. (10026017)
1998
38
Cutaneous pseudosarcomatous polyp--another variant of dermal lipoma or only an "ancient" skin tag? (9243368)
1997
39
Eruptive skin tags and keratoacanthomas in a patient with prolactinoma and colonic polyposis. (8075462)
1994
40
A method for removing the acrochordon (skin tag). (2308255)
1990
41
The accessory tragus--no ordinary skin tag. (2646335)
1989
42
Cutaneous skin tag of the foot. (6822720)
1983

Variations for Skin Tag

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Expression for genes affiliated with Skin Tag

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Search GEO for disease gene expression data for Skin Tag.

Pathways for genes affiliated with Skin Tag

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Pathways related to Skin Tag according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3INS, LEP
2
Show member pathways
9.3LEP, INS
3
Show member pathways
IL-9 Signaling Pathway36
Development Thrombopoietin regulated cell processes58
IL-7 Signaling Pathway36
Immune response IL 9 signaling pathway58
9.3LEP, INS
4
Show member pathways
9.3LEP, INS
59.3LEP, INS
6
Show member pathways
FOXA transcription factor networks36
9.1ESR1, INS
7
Show member pathways
Prolactin Signaling Pathway36
Development Prolactin receptor signaling58
Leptin signaling pathway36
8.5ESR1, LEP, INS
8
Show member pathways
8.0INS, LEP, PTCH1, ESR1

Compounds for genes affiliated with Skin Tag

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Compounds related to Skin Tag according to GeneCards Suite gene sharing:

(show all 43)
idCompoundScoreTop Affiliating Genes
1exenatide43 1210.8LEP, INS
2pramlintide43 1210.8INS, LEP
3sibutramine43 1210.8INS, LEP
4beta-hydroxybutyrate439.8INS, LEP
5acipimox43 2810.7LEP, INS
6intralipid439.7INS, LEP
7nash439.7INS, LEP
8telmisartan43 28 1211.7INS, LEP
9cortisone43 2410.7INS, LEP
10orlistat43 59 1211.7LEP, INS
11thiazolidinedione439.7INS, LEP
128-isoprostane439.7LEP, INS
13aicar43 24 1211.7LEP, INS
14dehydroepiandrosterone sulfate439.7LEP, INS
15fenofibrate43 49 1211.7LEP, INS
16glibenclamide43 28 49 5912.7INS, LEP
17metformin43 49 1211.7LEP, INS
18c-peptide439.6LEP, INS
19olanzapine43 49 28 24 1213.6INS, LEP
20dhea439.6INS, LEP
21triacylglycerol439.6LEP, INS
22pioglitazone28 43 49 1212.6LEP, INS
23androstenedione43 2410.6INS, LEP
24desogestrel43 1210.6ESR1, INS
25uric acid43 2410.6LEP, INS
26clomiphene citrate439.5INS, ESR1
27rosiglitazone28 43 49 24 1213.5INS, LEP
28troglitazone43 28 59 1212.5LEP, INS
29megestrol acetate439.4ESR1, LEP
30tibolone439.4LEP, ESR1
31letrozole43 49 59 1212.4ESR1, LEP
32naloxone43 28 49 1212.4LEP, ESR1
33carbohydrates439.3LEP, INS
34acth439.3LEP, INS
35estrone43 28 24 1212.2ESR1, LEP
36thyroxine43 2410.2INS, LEP
37dihydrotestosterone43 28 24 1212.1ESR1, LEP
38glycerol43 24 1211.0LEP, INS
39gnrh438.9ESR1, LEP, INS
40ly294002438.9INS, LEP, ESR1
41paraffin438.9ESR1, PTCH1, LEP
42testosterone43 59 24 1211.8ESR1, LEP, INS
43estrogen438.6INS, LEP, ESR1

GO Terms for genes affiliated with Skin Tag

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Biological processes related to Skin Tag according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1regulation of protein localizationGO:00328809.6PTCH1, INS
2positive regulation of insulin receptor signaling pathwayGO:00466289.6LEP, INS
3positive regulation of MAPK cascadeGO:00434109.4INS, LEP
4positive regulation of nitric-oxide synthase activityGO:00510009.4ESR1, INS
5glucose homeostasisGO:00425939.3INS, PTCH1
6regulation of insulin secretionGO:00507969.3INS, LEP
7positive regulation of nitric oxide biosynthetic processGO:00454299.3INS, ESR1
8glucose metabolic processGO:00060069.3LEP, INS
9negative regulation of sequence-specific DNA binding transcription factor activityGO:00434339.3ESR1, PTCH1
10response to estradiolGO:00323559.2ESR1, PTCH1
11energy reserve metabolic processGO:00061129.0LEP, INS

Molecular functions related to Skin Tag according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.3LEP, INS

Products for genes affiliated with Skin Tag

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Sources for Skin Tag

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet