MCID: SLP005
MIFTS: 54

Sleep Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Sleep Disorder

Summaries for Sleep Disorder

MedlinePlus : 41 is it hard for you to fall asleep or stay asleep through the night? do you wake up feeling tired or feel very sleepy during the day, even if you have had enough sleep? you might have a sleep disorder. the most common kinds are insomnia - a hard time falling or staying asleep sleep apnea - breathing interruptions during sleep restless legs syndrome - a tingling or prickly sensation in the legs narcolepsy - daytime "sleep attacks" nightmares, night terrors, sleepwalking, sleep talking, head banging, wetting the bed and grinding your teeth are kinds of sleep problems called parasomnias. there are treatments for most sleep disorders. sometimes just having good sleep habits can help.

MalaCards based summary : Sleep Disorder, also known as non-organic sleep disorder, is related to non 24 hour sleep wake disorder and narcolepsy, and has symptoms including back pain, cachexia and cyanosis. An important gene associated with Sleep Disorder is HCRT (Hypocretin Neuropeptide Precursor), and among its related pathways/superpathways are Circadian rythm related genes and Circadian rhythm. The drugs Alginic acid and Esomeprazole have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and testes, and related phenotypes are behavior/neurological and muscle

Disease Ontology : 12 A disease of mental health that involves disruption of sleep patterns.

Wikipedia : 72 A sleep disorder, or somnipathy, is a medical disorder of the sleep patterns of a person or animal. Some... more...

Related Diseases for Sleep Disorder

Diseases related to Sleep Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 186)
id Related Disease Score Top Affiliating Genes
1 non 24 hour sleep wake disorder 11.5
2 narcolepsy 11.3
3 mental retardation, autosomal recessive, 37 11.3
4 advanced sleep phase syndrome 11.3
5 sleep apnea 11.1
6 idiopathic hypersomnia 11.1
7 rem sleep behavior disorder 11.0
8 machado-joseph disease 11.0
9 periodic limb movement disorder 11.0
10 bruxism 10.9
11 hypersomnia 10.9
12 recurrent hypersomnia 10.9
13 chronic fatigue syndrome 10.9
14 angelman syndrome 10.9
15 creutzfeldt-jakob disease 10.8
16 advanced sleep phase syndrome, familial, 1 10.8
17 delayed sleep phase disorder 10.7
18 narcolepsy 1 10.7
19 immunodeficiency with hyper igm, type 5 10.6 CRY1 PER2 PER3
20 oculocutaneous albinism 10.6 HCRT PER2 PER3
21 obstructive sleep apnea 10.5
22 narcolepsy 7 10.5
23 brunner syndrome 10.5
24 progeroid short stature with pigmented nevi 10.5
25 chromosome 1q21.1 deletion syndrome 10.5
26 lyme disease - neurological complications 10.5
27 rosai-dorfman disease 10.4 HCRT HCRTR1 HCRTR2
28 laryngeal adductor paralysis 10.4 HCRTR1 PER2 PER3
29 orbit lymphoma 10.4 HCRTR1 HCRTR2
30 coarse face hypotonia constipation 10.4 HCRT HCRTR2
31 euthyroid sick syndrome 10.3 CRP PRL
32 diabetic encephalopathy 10.3 CRP HCRT LEP
33 periampullary adenoma 10.3 CRP HCRT LEP
34 mucolipidoses 10.2 CRP HCRT LEP
35 ovarian surface papilloma 10.2 HCRT MOG
36 survival motor neuron spinal muscular atrophy 10.2 CRP LEP PRL
37 pompholyx 10.0 CTNNBL1 FXYD1
38 central hypoventilation syndrome, congenital 10.0
39 obesity 10.0
40 epilepsy 10.0
41 neuromuscular disease 9.9
42 kleine-levin hibernation syndrome 9.9
43 achondroplasia 9.9
44 restless legs syndrome 9.9
45 multiple system atrophy 9.9
46 prader-willi syndrome 9.9
47 hepatopulmonary syndrome 9.8 HCRT HCRTR1 HCRTR2 LEP MOG
48 dyspepsia 9.8
49 systolic heart failure 9.8
50 myotonic dystrophy 9.8

Graphical network of the top 20 diseases related to Sleep Disorder:



Diseases related to Sleep Disorder

Symptoms & Phenotypes for Sleep Disorder

UMLS symptoms related to Sleep Disorder:


back pain, cachexia, cyanosis, dyspnea, edema, fever, headache, icterus, nervousness, nightmares, pain, sciatica, seizures, signs and symptoms, signs and symptoms, digestive, sleep disturbances, snoring, syncope, tremor, vertigo, chronic pain, psychiatric symptom, hallucinations, hypnagogic, reduced consciousness/confusion, vertigo/dizziness, hot flushes, sleeplessness, sluggishness

MGI Mouse Phenotypes related to Sleep Disorder:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.9 HCRTR2 LEP MOG PER2 PER3 PRL
2 muscle MP:0005369 9.56 CRY1 FXYD1 HCRT HCRTR2 LEP MOG
3 nervous system MP:0003631 9.32 ANK3 CRY1 HCRT HCRTR1 HCRTR2 LEP

Drugs & Therapeutics for Sleep Disorder

Drugs for Sleep Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 777)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alginic acid Approved, Experimental Phase 4 9005-32-7
2
Esomeprazole Approved, Investigational Phase 4,Phase 2,Phase 3 161796-78-7, 119141-88-7 4594 9579578
3
Clonidine Approved Phase 4,Phase 2 4205-90-7 2803
4
Doxepin Approved Phase 4,Phase 2,Early Phase 1 1668-19-5 667477 667468
5
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 75614-87-8, 51-45-6 774
6
Oxymetazoline Approved Phase 4,Phase 3,Phase 2,Phase 1 1491-59-4 4636
7
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 59-42-7 6041
8
Zolpidem Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 82626-48-0 5732
9
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 2,Phase 3 71-58-9
10 Piracetam Approved Phase 4,Phase 2 7491-74-9
11
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
12
Morphine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 57-27-2 5288826
13
Eszopiclone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 138729-47-2 969472
14
Fluoxetine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 54910-89-3 3386
15
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
16
Pramipexole Approved, Investigational Phase 4,Phase 3,Phase 2 104632-26-0 59868 119570
17
Ropinirole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 91374-20-8, 91374-21-9 5095 497540
18
Methylphenidate Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 113-45-1 4158
19
Trazodone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 19794-93-5 5533
20
Imipramine Approved Phase 4,Phase 3 50-49-7 3696
21
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2 148553-50-8 5486971
22
Acetylcholine Approved Phase 4,Phase 2,Phase 1 51-84-3 187
23
Citalopram Approved Phase 4,Phase 3,Phase 2 59729-33-8 2771
24
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
25
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 60142-96-3 3446
26
Nebivolol Approved, Investigational Phase 4 152520-56-4, 99200-09-6, 118457-14-0 71301
27
Donepezil Approved Phase 4,Phase 3,Phase 2,Phase 1 120014-06-4 3152
28
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
29
Acetazolamide Approved, Vet_approved Phase 4,Phase 3,Phase 2 59-66-5 1986
30
Armodafinil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112111-43-0
31
Modafinil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 68693-11-8 4236
32
Montelukast Approved Phase 4,Phase 3,Phase 2 158966-92-8 5281040
33
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-02-2 5743
34
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 6740-88-1 3821
35
Hydroxychloroquine Approved Phase 4,Phase 2 118-42-3 3652
36
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Early Phase 1 437-38-7 3345
37
Diphenhydramine Approved Phase 4,Phase 3,Phase 2,Phase 1 58-73-1, 147-24-0 3100
38
Promethazine Approved Phase 4,Phase 3,Phase 2,Phase 1 60-87-7 4927
39
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757
40
Sodium oxybate Approved Phase 4,Phase 3,Phase 2,Phase 1 502-85-2 5360545
41
Nitric Oxide Approved Phase 4 10102-43-9 145068
42
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 2078-54-8 4943
43
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
44
Budesonide Approved Phase 4,Phase 3,Phase 2 51333-22-3 63006 5281004
45
Mianserin Approved Phase 4,Phase 3,Phase 2 24219-97-4 4184
46
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
47
Levodopa Approved Phase 4,Phase 2,Phase 3 59-92-7 6047
48
Bupivacaine Approved, Investigational Phase 4,Phase 2 2180-92-9, 38396-39-3 2474
49
Mirtazapine Approved Phase 4,Phase 3,Phase 2,Phase 1 85650-52-8, 61337-67-5 4205
50
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1 2216-51-5 16666

Interventional clinical trials:

(show top 50) (show all 3597)

id Name Status NCT ID Phase Drugs
1 Sleep Disturbances in Hospitalized Children Unknown status NCT00749814 Phase 4
2 Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances Unknown status NCT02277886 Phase 4 sodium alginate;esomeprazole
3 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4 Ramelteon
4 Validation of DaTscan for Detection of Parkinson Disease Related Disorders Unknown status NCT02138682 Phase 4 l-123 Ioflupane
5 Study of Clonidine on Sleep Architecture in Children With Tourette's Syndrome (TS) and Comorbid ADHD Unknown status NCT00152750 Phase 4 APO-clonidine
6 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
7 Assess the Effect of a Single Dose of Zolpidem, Silenor & Placebo on Arousability, Ataxia/Balance & Cognitive Performance in Healthy Volunteers Unknown status NCT02353299 Phase 4 Silenor 6 mg;zolpidem 10 mg
8 Nasal Continuous Positive Airway Pressure (CPAP) in Chronic Fatigue and Sleep-disordered Breathing Unknown status NCT01368718 Phase 4
9 Herbal Alternatives for Menopause Symptoms (HALT Study) Unknown status NCT00169299 Phase 4 Black cohosh;Multibotanical preparation;Multibotanical preparation + dietary soy counseling;Conjugated equine estrogen +/- medroxyprogesterone acetate
10 Levetiracetam Treatment of Children With Subclinical Sleep-Activated Epileptiform Activity (SSEA) Unknown status NCT00393614 Phase 4 levetiracetam
11 Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status Unknown status NCT02135055 Phase 4 Midazolam;Morphine
12 Improving Sleep and Psychological Functioning in People With Depression and Insomnia Unknown status NCT00247624 Phase 4 Eszopiclone;Fluoxetine;Placebo
13 Effects of Ramelteon (8mg) Alone and in Combination With Multi-Component Behavioral Therapy on Sleep and Circadian Phase in Patients With Chronic Insomnia Unknown status NCT01180855 Phase 4 Placebo;Rozerem 8mg
14 Efficacy and Safety of 5 mg Sublingual Zolpidem vs 10mg Oral Zolpidem in the Induction and Maintenance of Sleep in Patients With Primary Insomnia Unknown status NCT01896336 Phase 4 Zolpidem Hemitartrate
15 Study to Observe the Effect of Mirapex ER® Once-daily (QD) Versus Twice-daily (BID) Unknown status NCT01515774 Phase 4 Mirapex ER
16 The Effects of Continuous Positive Airway Pressure on Overlap Syndrome Unknown status NCT00914264 Phase 4
17 Comparing Treatment With Melatonin to Treatment With Stimulants (Methylphenidate) in Children With Attention Deficit Hyperactivity Disorder and Sleep Difficulties Unknown status NCT01393574 Phase 4 Melatonin;Methylphenidate
18 Comparison of Quetiapine and Trazodone Treatment for Insomnia in Dually Diagnosed Veterans Unknown status NCT01662297 Phase 4 Quetiapine;Trazodone
19 Clinical Trial to Evaluate the Efficacy of FITOGYN Versus Placebo on the Vasomotor Symptomatology Associated With Menopause Unknown status NCT01116310 Phase 4 Soy isoflavones (Glycine max L) and red clover extract (Trifolium pretense L);Placebo
20 Effect of Atomoxetine on ADHD-Related Insomnia in Children and Adolescents Unknown status NCT00252278 Phase 4 atomoxetine
21 Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain Unknown status NCT00445133 Phase 4
22 Imipramine and Pregabalin Combination in Painful Polyneuropathy Unknown status NCT01047488 Phase 4 Imipramine;Pregabalin;Imipramine, pregabalin;Placebo
23 Effects of Botulinum Toxin Type A(Meditoxin®) on Sleep Bruxism Unknown status NCT01336439 Phase 4 Botulinum toxin type A (Meditoxin®)
24 Escitalopram and Sleep Architecture in Patients With Major Depressive Disorder Unknown status NCT00442481 Phase 4 Escitalopram
25 Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome Unknown status NCT01823770 Phase 4 Rotigotine;Placebo patchs
26 PROMAD: Predicting Therapeutic Outcome of Mandibular Advancement Device Treatment in Obstructive Sleep Apnea Unknown status NCT01532050 Phase 4
27 Brain Mechanisms and Targeting Insomnia in Major Depression Unknown status NCT00628914 Phase 4 escitalopram and eszopiclone;Escitalopram, eszopiclone, and placebo;Escitalopram
28 Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome Unknown status NCT02424695 Phase 4 Gabapentin Enacarbil (GEn);Placebo
29 CPAP and Nebivolol in Hypertensive Obstructive Sleep Apnea (OSA) Patients. Unknown status NCT01771406 Phase 4 Nebivolol
30 Donepezil Treatment for Sleep Apnea Patients Unknown status NCT00912457 Phase 4 donepezil;placebo
31 Multidisciplinary and Coordinated Follow-up Based on a Telemonitoring Web Platform for Improving CPAP Compliance in Low Cardiovascular Risk Sleep Apnea Patients : OPTISAS 1 Study Unknown status NCT01796769 Phase 4
32 Comparison of the Pentax AWS® With the Macintosh Laryngoscopic Intubation in Obstructive Sleep Apnea Syndrome Patients Unknown status NCT01428570 Phase 4
33 Blood Pressure Reduction Induced by CPAP in Sleep Apnea Patients at High Cardiovascular Risk : OPTISAS 2 Study Unknown status NCT01505959 Phase 4
34 The Endothelium Dysfunction in Patients of Obstructive Sleep Apnea Syndrome Unknown status NCT01699126 Phase 4 Statin
35 Validation of Functional Imaging as Predictive Tool for Outcome of Mandibular Replacement Appliance Therapy in Obstructive Sleep Apnea Hypopnea Syndrome Patients Unknown status NCT01524510 Phase 4
36 Cost-utility Study of Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnea Syndrome Patients Unknown status NCT01590420 Phase 4
37 Continuous Positive Airway Pressure in Sleep Apnea Syndrome: Effects on Metabolic Syndrome and Cardiac Damage Unknown status NCT00517777 Phase 4
38 Treatment of Cheyne Stocks Respiration With Adaptive Servo Ventilation and Bilevel Ventilators in Patients With Chronic Heart Failure Unknown status NCT00725595 Phase 4
39 Effect of Partial Sleep Deprivation on Cognition and Cytokines in Individuals With Major Depression Unknown status NCT00291239 Phase 4
40 Effects of Zolpidem CR® in Sleep and Heart Recovery in Cardiac Intensive Care Unit Patients Unknown status NCT01920334 Phase 4 Zolpidem CR 12.5mg;Placebo
41 Comparing Fluticasone-Salmeterol in Chronic Obstructive Pulmonary Disease (COPD) and Sleep Unknown status NCT00731770 Phase 4 fluticasone/salmeterol 250/50;placebo
42 Sleep Disorders and Gastroesophageal Reflux Disease (GERD) Completed NCT00287391 Phase 4 Rabeprazole
43 Atripla to Stribild Switch Study to Evaluate Sleep Disturbances Completed NCT02477527 Phase 4 Stribild
44 The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia Completed NCT01234675 Phase 4 Milnacipran;Milnacipran
45 Effects of Rasagiline on Sleep Disturbances in Parkinson's Disease Completed NCT01442610 Phase 4 Rasagiline;Placebo
46 A Phase IV Trial With Pramipexole to Investigate the Effects on RLS Symptoms and Sleep Disturbance in Patients With RLS Completed NCT00349531 Phase 4 Pramipexole
47 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
48 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disea Completed NCT00628342 Phase 4 Esomeprazole;Esomeprazole;Placebo
49 Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
50 Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED) Completed NCT00358527 Phase 4 Mometasone Furoate Nasal Spray (MFNS)

Search NIH Clinical Center for Sleep Disorder

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Sleep Disorder

Anatomical Context for Sleep Disorder

MalaCards organs/tissues related to Sleep Disorder:

39
Heart, Brain, Testes, Endothelial, Lung, Kidney, Liver

Publications for Sleep Disorder

Articles related to Sleep Disorder:

(show top 50) (show all 531)
id Title Authors Year
1
Spa therapy (balneotherapy) relieves mental stress, sleep disorder, and general health problems in sub-healthy people. ( 28936572 )
2017
2
Incidence of Prosthetic Complications associated with Implant-borne Prosthesis in a Sleep Disorder Center. ( 28874648 )
2017
3
Sleep Disorders: Restless Legs Syndrome. ( 28845959 )
2017
4
Epilepsy and sleep disorders improve in adolescents and adults with Angelman syndrome: A multicenter study on 46 patients. ( 28827041 )
2017
5
REM sleep disorder following general anesthesia in rats. ( 27771371 )
2017
6
Hyperbaric oxygen therapy is safe and effective for the treatment of sleep disorders in children with cerebral palsy. ( 28079475 )
2017
7
Sleep Disorder Diagnosis During Pregnancy and Risk of Preterm Birth. ( 28796676 )
2017
8
Trauma associated sleep disorder: A parasomnia induced by trauma. ( 28363448 )
2017
9
Sleep Disordered Breathing and Magnetic Resonance Imaging Findings in Children With Chiari Malformation Type I. ( 28943363 )
2017
10
Feasibility of a respiratory nurse specialist-led sleep disorder service in a district general hospital. ( 28675190 )
2017
11
Risk factors of sleep disorder after stroke: a meta-analysis. ( 27686181 )
2017
12
Sleep disorder, an independent risk associated with arterial stiffness in menopause. ( 28507296 )
2017
13
The influence of sleep disordered breathing in REM sleep behavior disorder. ( 28673760 )
2017
14
Serum brain-derived neurotrophic factor levels and sleep disorders in Chinese healthy and newly diagnosed type 2 diabetic subjects. ( 27038292 )
2017
15
Understanding the different relationships between mood and sleep disorders in several groups of non-oncological patients with chronic pain. ( 28945136 )
2017
16
Natural course and potential prognostic factors for sleep-disordered breathing in multiple system atrophy. ( 28522081 )
2017
17
Sleep Disorder as a Triggering Factor for Relapse in Multiple Sclerosis. ( 28359058 )
2017
18
Sleep Disorders, Restless Legs Syndrome, and Uremic Pruritus: Diagnosis and Treatment of Common Symptoms in DialysisA Patients. ( 27693261 )
2017
19
Sleep disordered breathing in children with achondroplasia. ( 27830579 )
2017
20
Sleep-disordered breathing and its management in children with achondroplasia. ( 28239978 )
2017
21
Sleep-disordered breathing in patients with neuromuscular disease. ( 28702830 )
2017
22
Dante Alighieri: evidence for sleep disorder-related cardiac autonomic dysfunctions. ( 28000594 )
2017
23
Sleep-Disordered Breathing in Neuromuscular Disease: Diagnostic and Therapeutic Challenges. ( 28372949 )
2017
24
Sleep-Disordered Breathing in Patients with Pulmonary Valve Incompetence Complicating Congenital Heart Disease. ( 27214563 )
2016
25
A Case of Undiagnosed Sleep Disorder with Hearing Difficulty and Dizziness. ( 27280102 )
2016
26
Non-invasive ventilation for sleep-disordered breathing in Smith-Magenis syndrome. ( 27495174 )
2016
27
Parkinson disease. Sleep disorder deficits suggest signature for early Parkinson disease. ( 26635212 )
2016
28
Response: "Best practices in the evaluation and treatment of foramen magnum stenosis in achondroplasia during infancy" and "is there a correlation between sleep disordered breathing and foramen magnum stenosis in children with achondroplasia?". ( 26754314 )
2016
29
Depressed visual field and mood are associated with sleep disorder in glaucoma patients. ( 27168309 )
2016
30
The association of relational and organizational job stress factors with sleep disorder: analysis of the 3rd Korean working conditions survey (2011). ( 27625788 )
2016
31
Autonomic dysfunction in primary sleep disorders. ( 27198946 )
2016
32
Respiratory symptoms, sleep-disordered breathing and biomarkers in nocturnal gastroesophageal reflux. ( 27646537 )
2016
33
How to Prepare for an Emergency or Disaster When You Have Lung Disease or a Sleep Disorder. ( 27689713 )
2016
34
Relationships between nutritional knowledge, obesity, and sleep disorder severity. ( 26843133 )
2016
35
The Relationship Between Sleep-Disordered Breathing Severity and Daytime Adaptive Functioning in Children with Down Syndrome. ( 27637582 )
2016
36
Patent foramen ovale: a novel cardiovascular risk factor in patients with sleep disordered breathing and high altitude dwellers? ( 27878796 )
2016
37
Post-Encephalitic Parkinsonism and Sleep Disorder Responsive to Immunological Treatment: A Case Report. ( 27118763 )
2016
38
Sleep disorders in Cornelia de Lange syndrome. ( 27133889 )
2016
39
Sleep Disorder, Gastrointestinal Problems and Behaviour Problems Seen in Autism Spectrum Disorder Children and Yoga as Therapy: A Descriptive Review. ( 28050484 )
2016
40
Does the Type of Multisystem Atrophy, Parkinsonism, or Cerebellar Ataxia Impact on the Nature of Sleep Disorders? ( 27844341 )
2016
41
Diagnosis of insomnia sleep disorder using short time frequency analysis of PSD approach applied on EEG signal using channel ROC-LOC. ( 28123658 )
2016
42
Frequency of prosthetic complications related to implant-borne prosthesis in a sleep disorder unit. ( 27700231 )
2016
43
Sleep-Disordered Breathing Exacerbates Muscle Vasoconstriction and Sympathetic Neural Activation in Patients with Systolic Heart Failure. ( 28029639 )
2016
44
Shift Work and Shift Work Sleep Disorder: Clinical and Organizational Perspectives. ( 28012806 )
2016
45
Low Prevalence of Sleep Disorders in Demyelinating Disease in a Northern Tenerife Population. ( 26951408 )
2016
46
Agreement of the International Classification of Sleep Disorders Criteria with polysomnography for sleep bruxism diagnosis: A preliminary study. ( 27460312 )
2016
47
Tryptophan for the sleeping disorder and mental symptom of new-type drug dependence: A randomized, double-blind, placebo-controlled trial. ( 27428201 )
2016
48
ROHHAD syndrome and evolution of sleep disordered breathing. ( 27473663 )
2016
49
Specific patterns of laryngeal electromyography during wakefulness are associated to sleep disordered breathing and nocturnal stridor in multiple system atrophy. ( 27510647 )
2016
50
The Risk of Sleep Disorder Among Persons with Mild Traumatic Brain Injury. ( 27079955 )
2016

Variations for Sleep Disorder

Expression for Sleep Disorder

Search GEO for disease gene expression data for Sleep Disorder.

Pathways for Sleep Disorder

Pathways related to Sleep Disorder according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
2
Show member pathways
10.97 CRY1 PER2 PER3
3 10.7 CRY1 PER2 PER3

GO Terms for Sleep Disorder

Biological processes related to Sleep Disorder according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 rhythmic process GO:0048511 9.7 CRY1 PER2 PER3
2 glucose homeostasis GO:0042593 9.67 CRY1 LEP TFAP2B
3 regulation of insulin secretion GO:0050796 9.63 LEP PER2 TFAP2B
4 circadian regulation of gene expression GO:0032922 9.54 CRY1 PER2 PER3
5 positive regulation of JAK-STAT cascade GO:0046427 9.51 LEP PRL
6 response to peptide GO:1901652 9.48 HCRTR1 HCRTR2
7 neuropeptide signaling pathway GO:0007218 9.46 HCRT HCRTR1 HCRTR2 NPS
8 negative regulation of lipid storage GO:0010888 9.43 CRP LEP
9 feeding behavior GO:0007631 9.43 HCRT HCRTR1 HCRTR2
10 negative regulation of circadian rhythm GO:0042754 9.4 CRY1 PER2
11 magnesium ion homeostasis GO:0010960 9.32 ANK3 TFAP2B
12 circadian rhythm GO:0007623 9.26 CRY1 LEP PER2 PER3
13 regulation of circadian sleep/wake cycle, sleep GO:0045187 8.8 HCRTR1 HCRTR2 PER3

Molecular functions related to Sleep Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription factor activity, transcription factor binding GO:0000989 8.96 CRY1 PER2
2 orexin receptor activity GO:0016499 8.62 HCRTR1 HCRTR2

Sources for Sleep Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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