SCCB
MCID: SML031
MIFTS: 30

Small Cell Carcinoma of the Bladder (SCCB) malady

Cancer diseases, Neuronal diseases, Nephrological diseases categories

Summaries for Small Cell Carcinoma of the Bladder

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32MalaCards
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MalaCards: Small Cell Carcinoma of the Bladder, also known as poorly differentiated neuroendocrine carcinoma of the bladder, is related to neuroendocrine carcinoma and brain cancer, and has symptoms including hematuria/microhematuria, ureteral/urethral/vesical/bladder neoplasm/tumor/carcinoma/cancer and pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria. An important gene associated with Small Cell Carcinoma of the Bladder is SYP (synaptophysin). The compounds dutp and smcc have been mentioned in the context of this disorder.

Aliases & Classifications for Small Cell Carcinoma of the Bladder

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42NIH Rare Diseases, 48Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases, Nephrological diseases


Characteristics (Orphanet epidemiological data):

48
poorly differentiated neuroendocrine carcinoma of the bladder:
Inheritance: Sporadic; Prevalence: <1/1000000; Age of onset: Adulthood; Age of death: Elderly


Aliases & Descriptions:

small cell carcinoma of the bladder 42 48
poorly differentiated neuroendocrine carcinoma of the bladder 42 48
small cell carcinoma of the urinary bladder 42 48
small cell bladder carcinoma 42 48
small cell bladder cancer 42 48
sccb 42 48


External Ids:

ICD10 via Orphanet26 C67

Related Diseases for Small Cell Carcinoma of the Bladder

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17GeneCards, 18GeneDecks
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Diseases related to Small Cell Carcinoma of the Bladder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1neuroendocrine carcinoma30.5SYP, ENO2
2brain cancer30.5TP53, ENO2, SYP
3lung small cell carcinoma30.5TP53, ENO2, SYP
4adenocarcinoma30.4SYP, ENO2, TP53
5lung cancer30.4SYP, ENO2, TP53
6transitional cell carcinoma30.3TP53, ENO2
7small cell carcinoma10.9
8bladder carcinoma10.9
9prostate small cell carcinoma10.5
10prostatitis10.5
11urinary bladder small cell neuroendocrine carcinoma10.3
12hypercalcemia10.3
13adrenal carcinoma10.3
14hepatitis a10.3
15bladder adenocarcinoma10.3
16bladder diverticulum10.3
17hepatitis10.3
18prostate adenocarcinoma10.3
19thyroiditis10.3
20bladder carcinoma in situ10.2
21bladder disease10.2
22bladder transitional cell carcinoma10.2
23dermatomyositis10.2
24in situ carcinoma10.2
25rhabdoid tumor10.0SYP
26melanotic neuroectodermal tumor10.0SYP
27pineoblastoma10.0SYP
28dysembryoplastic neuroepithelial tumor10.0SYP
29thymus cancer10.0SYP
30teratoma10.0ENO2
31cerebral primitive neuroectodermal tumor10.0ENO2
32gastrointestinal stromal tumor10.0ENO2
33amyotrophic lateral sclerosis10.0SYP
34wilms tumor10.0ENO2
35dementia10.0SYP
36meningioma10.0SYP
37pilocytic astrocytoma10.0SYP
38subependymal giant cell astrocytoma10.0ENO2, SYP
39ganglioneuroblastoma10.0ENO2, SYP
40ganglioglioma10.0SYP, ENO2
41hemangioblastoma10.0ENO2, SYP
42olfactory neuroblastoma10.0ENO2, SYP
43ependymoma10.0ENO2, SYP
44pineocytoma10.0ENO2, SYP
45neuroepithelioma10.0SYP, ENO2
46merkel cell carcinoma10.0SYP, ENO2
47prion disease10.0ENO2, SYP
48tubular adenocarcinoma10.0ENO2, SYP
49large cell carcinoma10.0ENO2, SYP
50pheochromocytoma10.0SYP, ENO2

Graphical network of the top 20 diseases related to Small Cell Carcinoma of the Bladder:



Diseases related to small cell carcinoma of the bladder

Clinical Features for Small Cell Carcinoma of the Bladder

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48Orphanet
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Symptoms:

48
  • hematuria/microhematuria
  • ureteral/urethral/vesical/bladder neoplasm/tumor/carcinoma/cancer
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • acute abdominal pain/colic
  • recurrent urinary infections
  • hypercalcemia

Drugs & Therapeutics for Small Cell Carcinoma of the Bladder

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Small Cell Carcinoma of the Bladder

Drug clinical trials:

Search ClinicalTrials for Small Cell Carcinoma of the Bladder

Search NIH Clinical Center for Small Cell Carcinoma of the Bladder

Search CenterWatch for Small Cell Carcinoma of the Bladder

Genetic Tests for Small Cell Carcinoma of the Bladder

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Anatomical Context for Small Cell Carcinoma of the Bladder

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Animal Models for Small Cell Carcinoma of the Bladder or affiliated genes

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Publications for Small Cell Carcinoma of the Bladder

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Genetic Variations for Small Cell Carcinoma of the Bladder

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Expression for genes affiliated with Small Cell Carcinoma of the Bladder

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Small Cell Carcinoma of the Bladder

Search GEO for disease gene expression data for Small Cell Carcinoma of the Bladder.

Pathways for genes affiliated with Small Cell Carcinoma of the Bladder

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Compounds for genes affiliated with Small Cell Carcinoma of the Bladder

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 24HMDB, 28IUPHAR
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Compounds related to Small Cell Carcinoma of the Bladder according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1dutp449.6TP53, SYP
2smcc449.5ENO2, SYP
3s 100449.5ENO2, SYP
4l-amino acid449.5ENO2, SYP
5hematoxylin449.4SYP, ENO2
6ganglioside449.4ENO2, SYP
7dbc-amp449.4SYP, ENO2
8silver449.4ENO2, SYP
9amine449.3ENO2, SYP
10carboplatin44 49 1111.3ENO2, TP53
11catecholamine449.3ENO2, SYP
12docetaxel44 49 59 1112.1ENO2, TP53
13formaldehyde44 2410.1ENO2, SYP
145-hydroxytryptamine449.0ENO2, SYP
15choline44 11 2410.8ENO2, SYP
16paraffin448.8SYP, ENO2, TP53
17cisplatin44 49 59 1111.8SYP, ENO2, TP53
18progesterone44 59 28 11 2412.8TP53, ENO2, SYP
19vegf448.7SYP, ENO2, TP53
20estrogen448.6TP53, ENO2, SYP
21retinoic acid44 249.5SYP, ENO2, TP53

GO Terms for genes affiliated with Small Cell Carcinoma of the Bladder

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16Gene Ontology
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Biological processes related to Small Cell Carcinoma of the Bladder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of DNA replicationGO:0081569.3TP53, TTF1

Products for genes affiliated with Small Cell Carcinoma of the Bladder

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Small Cell Carcinoma of the Bladder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet