MCID: SML034
MIFTS: 42

Small Cell Neuroendocrine Carcinoma malady

Categories: Cancer diseases, Respiratory diseases, Neuronal diseases

Aliases & Classifications for Small Cell Neuroendocrine Carcinoma

Aliases & Descriptions for Small Cell Neuroendocrine Carcinoma:

Name: Small Cell Neuroendocrine Carcinoma 12 14
Carcinoma, Small Cell 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0050875

Summaries for Small Cell Neuroendocrine Carcinoma

MalaCards based summary : Small Cell Neuroendocrine Carcinoma, also known as carcinoma, small cell, is related to urinary bladder small cell neuroendocrine carcinoma and colon small cell carcinoma. An important gene associated with Small Cell Neuroendocrine Carcinoma is SYP (Synaptophysin), and among its related pathways/superpathways are Glioma and Pathways in cancer. The drugs Cisplatin and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include cervix, prostate and breast, and related phenotypes are behavior/neurological and nervous system

Related Diseases for Small Cell Neuroendocrine Carcinoma

Diseases in the Large Cell Neuroendocrine Carcinoma family:

Small Cell Neuroendocrine Carcinoma

Diseases related to Small Cell Neuroendocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 274)
id Related Disease Score Top Affiliating Genes
1 urinary bladder small cell neuroendocrine carcinoma 12.2
2 colon small cell carcinoma 11.0
3 gallbladder small cell carcinoma 11.0
4 esophagus small cell carcinoma 11.0
5 ampulla of vater small cell carcinoma 11.0
6 small cell cancer of the lung, somatic 11.0
7 peroneal nerve paralysis 10.3 CHGA SYP
8 brain stem ependymoma 10.3 CHGA SYP
9 extrahepatic biliary papillomatosis 10.3 CHGA SYP
10 epithelioid malignant peripheral nerve sheath tumor 10.3 CHGA SYP
11 cartilage cancer 10.3 CHGA SYP
12 villous adenocarcinoma 10.3 CHGA SYP
13 jejunal neuroendocrine tumor 10.3 CHGA SYP
14 renal pelvis adenocarcinoma 10.3 CHGA SYP
15 barre-lieou syndrome 10.3 CHGA SYP
16 microinvasive cervical squamous cell carcinoma 10.3 CHGA SYP
17 gastric duplication cysts 10.3 CHGA SYP
18 sm-ahnmd 10.3 CHGA ENO2
19 diffuse cutaneous mastocytosis 10.3 CHGA SYP
20 prostatitis 10.3
21 infiltrating renal pelvis transitional cell carcinoma 10.3 ENO2 SYP
22 cavernous hemangioma of face 10.3 CHGA SYP
23 granulocytopenia 10.3 CHGA ENO2
24 skeletal-extraskeletal angiomatosis 10.3 ENO2 SYP
25 adult botryoid rhabdomyosarcoma 10.3 CHGA SYP
26 pemphigus foliaceus 10.3 ENO2 SYP
27 autosomal recessive stickler syndrome 10.3 ENO2 SYP
28 parietal lobe neoplasm 10.3 CHGA ENO2
29 urinary tract obstruction 10.3 CHGA ENO2
30 nephrogenic adenoma of urinary bladder 10.3 ENO2 SYP
31 hepatorenal syndrome 10.3 CHGA SYP
32 acalculous cholecystitis 10.3 CHGA SYP
33 intrahepatic bile duct adenoma 10.2 NCAM1 SYP
34 spinal stenosis 10.2 CHGA ENO2
35 gastrointestinal system benign neoplasm 10.2 CHGA ENO2
36 spinal chordoma 10.2 NCAM1 SYP
37 calcific tendinitis 10.2 CHGA SYP
38 neuritis 10.2 NCAM1 SYP
39 uterine corpus sarcoma 10.2 ENO2 NCAM1
40 mitochondrial complex ii deficiency 10.2 CHGA SYP
41 hypoparathyroidism-intellectual disability-dysmorphism syndrome 10.2 NCAM1 SYP
42 cavernous hemangioma of colon 10.2 ENO2 NCAM1
43 gastric teratoma 10.2 ENO2 NCAM1
44 movement disease 10.2 NCAM1 SYP
45 thymoma 10.2 ENO2 SYP
46 bone marrow cancer 10.2 CHGA SYP
47 thoracic benign neoplasm 10.2 ENO2 SYP
48 neuroendocrine carcinoma of the cervix 10.2
49 dysgerminoma of ovary 10.2 CHGA SYP
50 acinar cell cystadenocarcinoma 10.2 CHGA SYP

Graphical network of the top 20 diseases related to Small Cell Neuroendocrine Carcinoma:



Diseases related to Small Cell Neuroendocrine Carcinoma

Symptoms & Phenotypes for Small Cell Neuroendocrine Carcinoma

MGI Mouse Phenotypes related to Small Cell Neuroendocrine Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.8 TP53 CDKN2A ENO2 KIT NCAM1 PDGFRA
2 nervous system MP:0003631 9.7 CDKN2A ENO2 KIT NCAM1 PDGFRA SYP
3 pigmentation MP:0001186 9.26 CDKN2A KIT PDGFRA TP53
4 respiratory system MP:0005388 9.02 CDKN2A ENO2 KIT PDGFRA TP53

Drugs & Therapeutics for Small Cell Neuroendocrine Carcinoma

Drugs for Small Cell Neuroendocrine Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 228)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
2
Octreotide Approved, Investigational Phase 3,Phase 2,Phase 1 83150-76-9 383414 6400441
3
Oxaliplatin Approved, Investigational Phase 2, Phase 3,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
4
Fluorouracil Approved Phase 2, Phase 3,Phase 1 51-21-8 3385
5
Bevacizumab Approved, Investigational Phase 2, Phase 3, Phase 1 216974-75-3
6
Levoleucovorin Approved Phase 2, Phase 3,Phase 1 68538-85-2
7
Dopamine Approved Phase 3,Phase 2 51-61-6, 62-31-7 681
8
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
9
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
10
Everolimus Approved Phase 3,Phase 2,Phase 1 159351-69-6 6442177
11
Sirolimus Approved, Investigational Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
12
Somatostatin Approved Phase 3,Phase 1,Phase 2 38916-34-6, 51110-01-1 53481605
13
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
14
Doxycycline Approved, Investigational, Vet_approved Phase 3 564-25-0 54671203
15
Exenatide Approved, Investigational Phase 2, Phase 3 141758-74-9 15991534
16
Povidone-iodine Approved Phase 3 25655-41-8
17
leucovorin Approved, Nutraceutical Phase 2, Phase 3, Phase 1 58-05-9 54575, 6560146 143
18
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3,Phase 1 59-30-3 6037
19 pancreatic polypeptide Phase 2, Phase 3,Phase 1
20 interferons Phase 3,Phase 2,Phase 1
21 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
22 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
23 Angiogenesis Inhibitors Phase 2, Phase 3, Phase 1
24 Angiogenesis Modulating Agents Phase 2, Phase 3, Phase 1
25 Immunoglobulins Phase 3,Phase 2,Phase 1
26 Anti-Infective Agents Phase 3,Phase 2,Phase 1
27 Antibodies, Monoclonal Phase 3,Phase 2,Phase 1
28 Immunosuppressive Agents Phase 2, Phase 3, Phase 1
29 Interferon-alpha Phase 3,Phase 2
30 Liver Extracts Phase 3,Phase 2,Phase 1
31 Antimetabolites Phase 2, Phase 3,Phase 1
32 Antimetabolites, Antineoplastic Phase 2, Phase 3,Phase 1
33 Antibodies Phase 3,Phase 2,Phase 1
34 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1
35 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
36 Antiviral Agents Phase 3,Phase 2,Phase 1
37 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
38 Hormone Antagonists Phase 2, Phase 3, Phase 1, Early Phase 1
39 Dihydroxyphenylalanine Phase 3,Phase 2
40 Hormones Phase 2, Phase 3, Phase 1, Early Phase 1
41 Dopamine Agents Phase 3,Phase 2
42 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3, Phase 1, Early Phase 1
43 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
44 Antifungal Agents Phase 3,Phase 2,Phase 1
45 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
46
tremelimumab Phase 3,Phase 2
47 Hypoglycemic Agents Phase 2, Phase 3
48 Etoposide phosphate Phase 3,Phase 2,Phase 1
49 Incretins Phase 2, Phase 3
50 Antimalarials Phase 3

Interventional clinical trials:

(show top 50) (show all 204)
id Name Status NCT ID Phase
1 Radiolabeled Molecules for Medullary Thyroid Cancer Recruiting NCT01915485 Phase 4
2 Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors Unknown status NCT00227617 Phase 2, Phase 3
3 An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation Completed NCT00132704 Phase 3
4 Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases Completed NCT00540969 Phase 3
5 Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor Completed NCT00412061 Phase 3
6 A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion Recruiting NCT02583282 Phase 3
7 Durvalumab+/- Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (Caspian) Recruiting NCT03043872 Phase 3
8 New Imaging Procedure for the Localisation of Insulinoma and Transplanted Islet Cells Recruiting NCT02127541 Phase 2, Phase 3
9 18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety Recruiting NCT03042416 Phase 3
10 Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor Active, not recruiting NCT00569127 Phase 3
11 A Study Comparing Treatment With 177Lu-DOTA0-Tyr3-Octreotate to Octreotide LAR in Patients With Inoperable, Progressive, Somatostatin Receptor Positive Midgut Carcinoid Tumours Active, not recruiting NCT01578239 Phase 3
12 An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer Active, not recruiting NCT00410761 Phase 3
13 Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer Active, not recruiting NCT00704730 Phase 3
14 Radiation Therapy in Preventing Brain Metastases in Patients With Small Cell Lung Cancer Withdrawn NCT00006344 Phase 3
15 Study of Relationship Between UGT1A1 Gene Polymorphism and Toxicity and Efficacy of Irinotecan in Small Cell Lung Cancer Unknown status NCT01635400 Phase 2
16 Antineoplaston Therapy in Treating Patients With Recurrent or Extensive-Stage Small Cell Lung Cancer Unknown status NCT00003496 Phase 2
17 Panitumumab, Cisplatin, and Pelvic Radiation Therapy in Treating Patients With Stage IB, Stage II, or Stage III Cervical Cancer Unknown status NCT01158248 Phase 2
18 Imaging Study in Patients With Cancer of the Head & Neck, Lung, Renal Cell, Brain, Lymphoma and Neuroendocrine Tumours Unknown status NCT00323076 Phase 1, Phase 2
19 Hyperthermia/Thermal Therapy With Chemotherapy to Treat Inoperable or Metastatic Tumors Unknown status NCT00178698 Phase 2
20 68-Ga-labeled Octreotide Analogues PET in Duodenal-pancreatic Neuroendocrine Tumours Unknown status NCT01673906 Phase 2
21 Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients Unknown status NCT01134250 Phase 1, Phase 2
22 Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer Unknown status NCT00019474 Phase 2
23 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Cancer. Completed NCT00003943 Phase 2
24 Hypofractionated Radiotherapy for Limited Stage Small Cell Lung Cancer Completed NCT00907569 Phase 2
25 ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer Completed NCT00309959 Phase 2
26 Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer Completed NCT00217633 Phase 2
27 Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer Completed NCT01266447 Phase 2
28 Cetuximab and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer Completed NCT00101192 Phase 2
29 Paclitaxel, Topotecan, and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer Completed NCT00276796 Phase 2
30 Radiation Therapy Plus Paclitaxel and Cisplatin in Treating Patients With Cervical Cancer Completed NCT00003379 Phase 1, Phase 2
31 Study of Hsp90 Inhibitor, STA-9090 for Relapsed or Refractory Small Cell Lung Cancer Completed NCT01173523 Phase 2
32 Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma Completed NCT00093782 Phase 2
33 S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer Completed NCT00003549 Phase 2
34 Extension Study of the Safety and Efficacy of Atiprimod Treatment in Neuroendocrine Carcinoma Completed NCT00663429 Phase 2
35 Avastin (Bevacizumab) and RAD001 (Everolimus) in Advanced Low or Intermediate Grade Neuroendocrine Carcinoma Completed NCT00607113 Phase 2
36 Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers Completed NCT01121939 Phase 2
37 Safety and Efficacy of Atiprimod Treatment for Patients With Low to Intermediate Grade Neuroendocrine Carcinoma Completed NCT00388063 Phase 2
38 Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors Completed NCT00019331 Phase 2
39 Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer Completed NCT00328861 Phase 2
40 Clinical and Translational Study of MK-0646 in Patients With Metastatic Neuroendocrine Tumors (NET) Completed NCT00610129 Phase 2
41 BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy. Completed NCT01658436 Phase 2
42 Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Metastatic Kidney Cancer Completed NCT00004135 Phase 2
43 CAR T Cell Receptor Immunotherapy Targeting VEGFR2 for Patients With Metastatic Cancer Completed NCT01218867 Phase 1, Phase 2
44 A Ph 2 Study of Fosbretabulin in Subjects w Pancreatic or Gastrointestinal Neuroendocrine Tumors w Elevated Biomarkers Completed NCT02132468 Phase 2
45 Pemetrexed in Patients With Advanced Neuroendocrine Tumors Completed NCT00424723 Phase 2
46 Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer Completed NCT00005049 Phase 2
47 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2
48 Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer Completed NCT00903396 Phase 2
49 A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer Completed NCT00358956 Phase 2
50 Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction Completed NCT00004911 Phase 1, Phase 2

Search NIH Clinical Center for Small Cell Neuroendocrine Carcinoma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Small Cell Neuroendocrine Carcinoma

Anatomical Context for Small Cell Neuroendocrine Carcinoma

MalaCards organs/tissues related to Small Cell Neuroendocrine Carcinoma:

39
Cervix, Prostate, Breast, Lung, Colon, Thyroid, Tongue

Publications for Small Cell Neuroendocrine Carcinoma

Articles related to Small Cell Neuroendocrine Carcinoma:

(show top 50) (show all 130)
id Title Authors Year
1
Postradiotherapy small cell neuroendocrine carcinoma of base of tongue: An unusual clinical and site presentation. ( 27853043 )
2017
2
Combination therapy with topotecan, paclitaxel, and bevacizumab improves progression-free survival in recurrent small cell neuroendocrine carcinoma of the cervix. ( 27823771 )
2017
3
Small cell neuroendocrine carcinoma of the endometrium with pulmonary metastasis: A clinicopathologic study of a case and a brief review of the literature. ( 26900464 )
2016
4
Thymic Small Cell Neuroendocrine Carcinoma Displayed on 18F-FDG PET/CT Imaging. ( 26673232 )
2016
5
Early Detection of Bone Metastasis in Small Cell Neuroendocrine Carcinoma of the Cervix by 68Ga-DOTATATE PET/CT Imaging. ( 28005640 )
2016
6
Small-cell Neuroendocrine Carcinoma Associated with Non Adenoma-like Raised Lesion in a Patient with Long-standing Ulcerative Colitis. ( 26912579 )
2016
7
Alternative Splicing Provides a Novel Molecular Mechanism for Prostatic Small-cell Neuroendocrine Carcinoma. ( 27481176 )
2016
8
(68)Ga-DOTANOC PET-CT in a rare case of metastatic small cell neuroendocrine carcinoma of paranasal sinus. ( 26656431 )
2016
9
Colonic small cell neuroendocrine carcinoma in a patient with long-standing ulcerative colitis treated with azathioprine. ( 27103360 )
2016
10
The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma. ( 26832214 )
2016
11
An Extremely Rare Case of Advanced Metastatic Small Cell Neuroendocrine Carcinoma of Sinonasal Tract. ( 27529044 )
2016
12
Small cell neuroendocrine carcinoma of tracheostomy site in a patient with a history of juvenile laryngeal papillomatosis. ( 27507691 )
2016
13
A Case of Pancreatic Small Cell Neuroendocrine Carcinoma Associated With SIADH. ( 27077720 )
2016
14
Mediastinum primary small cell neuroendocrine carcinoma. ( 27095946 )
2016
15
Sinonasal small cell neuroendocrine carcinoma: a systematic review of 80 patients. ( 26880574 )
2016
16
Ampullary carcinosarcoma with osteosarcomatous, small cell neuroendocrine carcinoma and conventional adenocarcinoma components; First report. ( 27640104 )
2016
17
Primary Ureteral Thyroid Transcription Factor 1-Positive Small Cell Neuroendocrine Carcinoma: Case Report and Review of the Literature. ( 26162396 )
2015
18
Primary small cell neuroendocrine carcinoma of the oral cavity: A case report and review of the literature. ( 26622589 )
2015
19
Small cell neuroendocrine carcinoma of the esophagus. ( 25645990 )
2015
20
A Case of Focal Small-cell Neuroendocrine Carcinoma in the Vicinity of the Extrahepatic Bile Duct, Adjacent to an Extensive Biliary Intraepithelial Neoplasm: A Diagnostic Challenge with Major Clinical Implications. ( 26254373 )
2015
21
Small cell neuroendocrine carcinoma of larynx: case series and literature review. ( 26173932 )
2015
22
A multicenter study of the importance of systemic chemotherapy for patients with small-cell neuroendocrine carcinoma of the uterine cervix. ( 25500455 )
2015
23
PD-L1 expression in small cell neuroendocrine carcinomas. ( 25582496 )
2015
24
A rare cause of constipation: obstructing small cell neuroendocrine carcinoma of the anal canal. ( 26198995 )
2015
25
Small cell neuroendocrine carcinoma of the ethmoid sinus revealed by syndrome of inappropriate antidiuretic hormone secretion. ( 26048029 )
2015
26
Clinical outcomes of small cell neuroendocrine carcinoma and adenocarcinoma of the gallbladder. ( 25574101 )
2015
27
Should patients with laryngeal small cell neuroendocrine carcinoma receive prophylactic cranial irradiation? ( 26530293 )
2015
28
p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma. ( 25512615 )
2015
29
Small cell neuroendocrine carcinoma of the posterior tongue. ( 26458628 )
2015
30
Prognostic Factors of Surgically Treated Early-Stage Small Cell Neuroendocrine Carcinoma of the Cervix. ( 26186071 )
2015
31
The CT and MRI observations of small cell neuroendocrine carcinoma in paranasal sinuses. ( 25888820 )
2015
32
Metastatic Small-Cell Neuroendocrine Carcinoma Simulating Circumscribed Choroidal Hemangioma. ( 27171748 )
2015
33
Clinical features and hypoxic marker expression of primary sinonasal and laryngeal small-cell neuroendocrine carcinoma: a small case series. ( 24980293 )
2014
34
Rare sinonasal small cell neuroendocrine carcinoma evaluated by F-18-FDG PET/MRI. ( 24510632 )
2014
35
Cutaneous metastases of prostatic small cell neuroendocrine carcinoma. ( 25075810 )
2014
36
Primary small cell neuroendocrine carcinoma of the tonsil: a case report and review of the literature. ( 24966986 )
2014
37
Metastatic small cell neuroendocrine carcinoma of the pyriform sinus evaluated by (18)F-FDG PET/CT. ( 25018134 )
2014
38
Prognostic Factors for Small Cell Neuroendocrine Carcinoma of the Uterine Cervix: An Institutional Experience. ( 24401981 )
2014
39
Response to MEK inhibitor in small cell neuroendocrine carcinoma of the cervix with a KRAS mutation. ( 26075998 )
2014
40
Small cell neuroendocrine carcinoma of the ureter: A case report and literature review. ( 24520292 )
2014
41
Small-Cell Neuroendocrine Carcinoma, Not Merkel Cell Carcinoma, in the Sinonasal Region: A Case Report. ( 25196095 )
2014
42
Small cell neuroendocrine carcinoma of the endometrium: AA clinicopathologic study of six cases. ( 25286790 )
2014
43
Pseudomesotheliomatous small cell neuroendocrine carcinoma of the lung with calretinin expression. ( 25040312 )
2014
44
Primary small cell neuroendocrine carcinoma of paranasal sinuses. ( 25057271 )
2014
45
Concomitant small cell neuroendocrine carcinoma of gallbladder and breast cancer. ( 25328753 )
2014
46
Submucosal small-cell neuroendocrine carcinoma of the larynx detected using (18)F-fluorodeoxyglucose positron emission tomography/computed tomography: A case report and review of the literature. ( 25120658 )
2014
47
Radiation-Associated Small Cell Neuroendocrine Carcinoma of the Thyroid: A Case Report with Molecular Analyses. ( 23844610 )
2014
48
Small cell neuroendocrine carcinoma of the cervix: a rare entity. ( 24701511 )
2014
49
Primary small-cell neuroendocrine carcinoma of the male breast: a rare case report with review of the literature. ( 24851054 )
2014
50
Spontaneous rupture of hepatic metastasis from small cell neuroendocrine carcinoma of maxillary sinus. ( 24767405 )
2014

Variations for Small Cell Neuroendocrine Carcinoma

Copy number variations for Small Cell Neuroendocrine Carcinoma from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 226170 7 55086725 55275030 Not increased EGFR Small cell neuroendocrine carcinoma

Expression for Small Cell Neuroendocrine Carcinoma

Search GEO for disease gene expression data for Small Cell Neuroendocrine Carcinoma.

Pathways for Small Cell Neuroendocrine Carcinoma

GO Terms for Small Cell Neuroendocrine Carcinoma

Cellular components related to Small Cell Neuroendocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.13 KIT NCAM1 PDGFRA
2 mast cell granule GO:0042629 8.62 CHGA KIT

Biological processes related to Small Cell Neuroendocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.63 KIT NCAM1 PDGFRA
2 phosphatidylinositol-mediated signaling GO:0048015 9.5 KIT PDGFRA TP53
3 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.43 KIT PDGFRA
4 mast cell degranulation GO:0043303 9.4 CHGA KIT
5 replicative senescence GO:0090399 9.37 CDKN2A TP53
6 somatic stem cell division GO:0048103 9.26 CDKN2A KIT
7 positive regulation of phospholipase C activity GO:0010863 9.16 KIT PDGFRA
8 mast cell chemotaxis GO:0002551 8.96 CHGA KIT
9 mast cell cytokine production GO:0032762 8.62 CHGA KIT

Molecular functions related to Small Cell Neuroendocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.8 KIT NCAM1 PDGFRA

Sources for Small Cell Neuroendocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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