MCID: SML025
MIFTS: 25

Small Non-Cleaved Cell Lymphoma

Categories: Immune diseases

Aliases & Classifications for Small Non-Cleaved Cell Lymphoma

MalaCards integrated aliases for Small Non-Cleaved Cell Lymphoma:

Name: Small Non-Cleaved Cell Lymphoma 37
Lymphoma, Small Noncleaved-Cell 69

Classifications:



Summaries for Small Non-Cleaved Cell Lymphoma

MalaCards based summary : Small Non-Cleaved Cell Lymphoma, also known as lymphoma, small noncleaved-cell, is related to burkitt lymphoma and lymphoma. An important gene associated with Small Non-Cleaved Cell Lymphoma is MYC (MYC Proto-Oncogene, BHLH Transcription Factor). The drugs Cyclophosphamide and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and b cells.

Related Diseases for Small Non-Cleaved Cell Lymphoma

Diseases related to Small Non-Cleaved Cell Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 burkitt lymphoma 11.6
2 lymphoma 10.6
3 leukemia 10.1
4 leukemia, chronic lymphocytic 2 9.9
5 leukemia, chronic lymphocytic 9.9
6 lymphoblastic lymphoma 9.9
7 lymphoblastic leukemia 9.9
8 leukemia, b-cell, chronic 9.9

Graphical network of the top 20 diseases related to Small Non-Cleaved Cell Lymphoma:



Diseases related to Small Non-Cleaved Cell Lymphoma

Symptoms & Phenotypes for Small Non-Cleaved Cell Lymphoma

Drugs & Therapeutics for Small Non-Cleaved Cell Lymphoma

Drugs for Small Non-Cleaved Cell Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 272)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
2
Lenograstim Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 135968-09-1
3 Thiotepa Approved, Investigational Phase 4,Phase 2,Phase 3 52-24-4 5453
4 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
5 Antilymphocyte Serum Phase 4,Phase 2,Phase 3,Phase 1
6 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
7 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
8
Ketamine Approved, Vet_approved Phase 3 6740-88-1 3821
9
rituximab Approved Phase 3,Phase 2,Phase 1 174722-31-7 10201696
10
Vincristine Approved, Investigational Phase 3,Phase 1,Phase 2 2068-78-2, 57-22-7 5978
11
Cytarabine Approved, Investigational Phase 3,Phase 2,Phase 1 147-94-4 6253
12
Etoposide Approved Phase 3,Phase 2,Phase 1,Early Phase 1 33419-42-0 36462
13
Methotrexate Approved Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
14
Methylprednisolone Approved, Vet_approved Phase 3,Phase 2,Phase 1 83-43-2 6741
15
Prednisolone Approved, Vet_approved Phase 3,Phase 2,Phase 1 50-24-8 5755
16
Busulfan Approved, Investigational Phase 3,Phase 2,Early Phase 1 55-98-1 2478
17
Fludarabine Approved Phase 2, Phase 3, Phase 1 21679-14-1, 75607-67-9 30751
18
Melphalan Approved Phase 2, Phase 3,Phase 1 148-82-3 460612 4053
19
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
20
Prednisone Approved, Vet_approved Phase 3,Phase 2,Phase 1 53-03-2 5865
21
Piperacillin Approved Phase 3 66258-76-2 43672
22
Tazobactam Approved Phase 3 89786-04-9 123630
23
Vancomycin Approved Phase 3 1404-90-6 14969 441141
24
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
25
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
26
Hydrocortisone Approved, Vet_approved Phase 3,Phase 2 50-23-7 657311 5754
27
Ondansetron Approved Phase 3,Phase 2 99614-02-5 4595
28
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
29
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
30
Levoleucovorin Approved, Investigational Phase 3,Phase 2,Phase 1 68538-85-2
31
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
32
Captopril Approved Phase 3 62571-86-2 44093
33
Palivizumab Approved, Investigational Phase 3 188039-54-5
34
Ribavirin Approved Phase 3 36791-04-5 37542
35
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
36
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
37
Aldesleukin Approved Phase 3,Phase 2,Phase 1 110942-02-4, 85898-30-2
38
Carboplatin Approved Phase 2, Phase 3,Phase 1 41575-94-4 10339178 38904 498142
39
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
40
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 143 6006
41
Glutamic Acid Approved, Nutraceutical Phase 3 56-86-0 33032
42
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
43
Butyric Acid Experimental, Investigational Phase 3,Phase 2,Phase 1 107-92-6 264
44 Analgesics Phase 3,Phase 1,Phase 2
45 Anesthetics Phase 3
46 Anesthetics, Dissociative Phase 3
47 Anesthetics, General Phase 3
48 Anesthetics, Intravenous Phase 3
49 Central Nervous System Depressants Phase 3,Phase 2
50 Excitatory Amino Acid Antagonists Phase 3

Interventional clinical trials:

(show top 50) (show all 212)

# Name Status NCT ID Phase Drugs
1 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4 cyclophosphamide;thiotepa
2 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3 ketamine hydrochloride
3 Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Previously Untreated HIV-Associated Non-Hodgkin's Lymphoma Completed NCT00003595 Phase 3 CHOP regimen;cyclophosphamide;doxorubicin hydrochloride;prednisone;vincristine sulfate
4 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
5 Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count Completed NCT00003805 Phase 3 piperacillin sodium;piperacillin-tazobactam;tazobactam sodium;vancomycin
6 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
7 Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Completed NCT00369564 Phase 3 glutamic acid
8 TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma Completed NCT00002757 Phase 3 cyclophosphamide;cytarabine;doxorubicin hydrochloride;etoposide;methotrexate;prednisolone;prednisone;therapeutic hydrocortisone;vincristine sulfate
9 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3 supersaturated calcium phosphate rinse
10 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3 ondansetron
11 Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia Completed NCT00005977 Phase 3 cyclophosphamide;cytarabine;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;leucovorin calcium;methotrexate;vincristine sulfate
12 A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families Completed NCT00782145 Phase 3
13 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
14 Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer Completed NCT00265837 Phase 3
15 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
16 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
17 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
18 Graft-Versus-Host Disease in Treating Patients With Recurrent or Refractory Lymphoma or Hodgkin's Disease Completed NCT00003414 Phase 3 busulfan;cyclophosphamide;cyclosporine
19 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
20 Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer Active, not recruiting NCT00003816 Phase 2, Phase 3 busulfan;carboplatin;cyclophosphamide;etoposide;fludarabine phosphate;melphalan;thiotepa
21 Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases Unknown status NCT00084695 Phase 2 busulfan;cyclophosphamide;fludarabine phosphate;melphalan;methylprednisolone
22 Monoclonal Antibody Therapy in Treating Patients With Lymphoproliferative Disorder Associated With Immunosuppression Therapy Unknown status NCT00003716 Phase 2
23 Valproic Acid in Treating Patients With Previously Treated Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Chronic Lymphocytic Leukemia Unknown status NCT01016990 Phase 2 valproic acid
24 Gene Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma Unknown status NCT00003942 Phase 1, Phase 2
25 Combination Chemotherapy Plus Filgrastim in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma Unknown status NCT00032149 Phase 1, Phase 2 cyclophosphamide;etoposide;mitoxantrone hydrochloride;prednisolone;vincristine sulfate
26 Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation Unknown status NCT00036712 Phase 2
27 Umbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic Anemia Unknown status NCT00008164 Phase 2
28 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2 indinavir sulfate;ritonavir
29 Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma Unknown status NCT00621036 Phase 2 methotrexate;thiotepa
30 Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia Completed NCT00002494 Phase 2 cyclophosphamide;cytarabine;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;leucovorin calcium;mesna;methotrexate;prednisone;therapeutic hydrocortisone;vincristine sulfate
31 Combination Chemotherapy and Rituximab in Treating Patients With HIV-Associated Stage I, Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma Completed NCT00049036 Phase 2 etoposide;doxorubicin hydrochloride;vincristine sulfate;prednisone;cyclophosphamide
32 Interleukin-12 Following Chemotherapy in Treating Patients With Refractory HIV-Associated Non-Hodgkin's Lymphoma Completed NCT00003575 Phase 2 etoposide;ifosfamide
33 Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma Completed NCT00057811 Phase 2 doxorubicin hydrochloride;cyclophosphamide;methotrexate;rasburicase;leucovorin calcium;prednisone;methylprednisolone;cytarabine;etoposide;vincristine sulfate;hydrocortisone sodium succinate
34 Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment Completed NCT00005811 Phase 2 topotecan hydrochloride
35 Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's Lymphoma Completed NCT00002738 Phase 2 leucovorin calcium;trimetrexate glucuronate
36 Combination Chemotherapy in Treating Pediatric Patients With Stage III or IV Non-Hodgkin's Lymphoma Completed NCT00002691 Phase 2 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;leucovorin calcium;mesna;methotrexate;vincristine sulfate
37 Combination Chemotherapy and Bone Marrow Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome Completed NCT00002502 Phase 2 busulfan;cyclophosphamide;cytarabine
38 Radiation Therapy and Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With High-Grade Lymphoma or Acute Lymphoblastic Leukemia Completed NCT00004898 Phase 1, Phase 2 cyclophosphamide;etoposide
39 Study of @neWorld: A Virtual Community for Children With Cancer Completed NCT00070421 Phase 1, Phase 2
40 Interferon Alfa in Treating Children With HIV-Related Cancer Completed NCT00002621 Phase 2
41 Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy Completed NCT00066599 Phase 2 voriconazole
42 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
43 Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00027937 Phase 2 busulfan;cyclophosphamide;melphalan;paclitaxel;thiotepa
44 Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tumors Completed NCT00365768 Phase 2 Glutamine
45 Rituximab in Treating Young Patients Who Are Receiving Chemotherapy for B-Cell Non-Hodgkin's Lymphoma or B-Cell Acute Lymphoblastic Leukemia Completed NCT00324779 Phase 2
46 Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia and Diffuse Non-Hodgkin's Lymphoma Completed NCT00018954 Phase 2 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;doxorubicin hydrochloride;etoposide;ifosfamide;mercaptopurine;methotrexate;prednisone;vincristine sulfate
47 Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer Completed NCT00589563 Phase 2 cyclophosphamide;etoposide;fludarabine phosphate;melphalan;methotrexate;sirolimus;tacrolimus
48 Busulfan, Melphalan, and Thiotepa in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Hodgkin's or Non-Hodgkin's Lymphoma Completed NCT00238433 Phase 2 busulfan;melphalan;thiotepa
49 Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00096096 Phase 2 mycophenolate mofetil;tacrolimus
50 Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma Completed NCT00002471 Phase 2 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;leucovorin calcium;methotrexate;methylprednisolone;therapeutic hydrocortisone;thiotepa;vincristine sulfate

Search NIH Clinical Center for Small Non-Cleaved Cell Lymphoma

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Small Non-Cleaved Cell Lymphoma cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Small Non-Cleaved Cell Lymphoma:
Blood stem cell transplantation for hematological diseases
Hematopoietic stem cells for treatment of hematologic malignancies
Embryonic/Adult Cultured Cells Related to Small Non-Cleaved Cell Lymphoma:
Peripheral blood-derived hematopoietic stem cells (family)
Bone marrow-derived hematopoietic stem cells

Genetic Tests for Small Non-Cleaved Cell Lymphoma

Anatomical Context for Small Non-Cleaved Cell Lymphoma

MalaCards organs/tissues related to Small Non-Cleaved Cell Lymphoma:

38
Bone, Bone Marrow, B Cells, T Cells, Kidney, Brain, B Lymphoblasts

Publications for Small Non-Cleaved Cell Lymphoma

Articles related to Small Non-Cleaved Cell Lymphoma:

(show all 18)
# Title Authors Year
1
Long-term survival in patients with human immunodeficiency virus-associated small non-cleaved cell lymphoma: the role for short course intensive chemotherapy. ( 14579241 )
2003
2
Human herpesvirus-8 (HHV-8) associated with small non-cleaved cell lymphoma in a child with AIDS. ( 10072113 )
1999
3
Diagnosis of small non-cleaved cell lymphoma by fine needle aspiration utilizing cytomorphologic features combined with cytogenetic analysis. ( 9167698 )
1997
4
Genetic heterogeneity of AIDS-related small non-cleaved cell lymphoma. ( 9332331 )
1997
5
Bone marrow involvement in lymphoblastic lymphoma and small non-cleaved cell lymphoma: the role of trephine biopsy. ( 9407729 )
1997
6
Adults and children with small non-cleaved-cell lymphoma have a similar excellent outcome when treated with the same chemotherapy regimen. ( 8622041 )
1996
7
Is the small non-cleaved-cell lymphoma histologic subtype a poor prognostic factor in adult patients? A case-controlled analysis. The Groupe d'Etude des Lymphomes de l'Adulte. ( 8558204 )
1996
8
Azothymidine and interferon-alpha are active in AIDS-associated small non-cleaved cell lymphoma but not large-cell lymphoma. ( 8814017 )
1996
9
Treatment of small non-cleaved cell lymphoma in the adult. ( 8991114 )
1996
10
Treatment of advanced stage diffuse, small non-cleaved cell lymphoma in childhood: further experience with total therapy B. ( 8084306 )
1994
11
Prognostic factors for therapeutic outcome of diffuse small non-cleaved cell lymphoma in adults. ( 8037180 )
1994
12
Results of treatment of small non-cleaved cell lymphoma in patients without positive HIV serology. ( 7683228 )
1993
13
The role of gallium-67 tumour scintigraphy in patients with small, non-cleaved cell lymphoma. ( 8440267 )
1993
14
Small non-cleaved-cell lymphoma (undifferentiated lymphoma, Burkitt's type) in American adults: results with treatment designed for acute lymphoblastic leukemia. ( 2003515 )
1991
15
Pleural effusion is associated with a poor treatment outcome in stage III small non-cleaved cell lymphoma. ( 1999958 )
1991
16
Small non-cleaved cell lymphoma in adults. ( 1897513 )
1991
17
Transformation of chronic lymphocytic leukemia to small non-cleaved cell lymphoma: a cytogenetic, immunological, and molecular study. ( 1961039 )
1991
18
Biology and treatment of small non-cleaved cell lymphoma. ( 2578020 )
1989

Variations for Small Non-Cleaved Cell Lymphoma

Expression for Small Non-Cleaved Cell Lymphoma

Search GEO for disease gene expression data for Small Non-Cleaved Cell Lymphoma.

Pathways for Small Non-Cleaved Cell Lymphoma

GO Terms for Small Non-Cleaved Cell Lymphoma

Sources for Small Non-Cleaved Cell Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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