Spastic Paraplegia 17 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Aliases & Classifications for Spastic Paraplegia 17

Sources:
²⁴GeneTests, ²⁷GTR, ⁴⁸NIH Rare Diseases, ⁶⁸UMLS
See all MalaCards sources

Aliases & Descriptions for Spastic Paraplegia 17:

Name: Spastic Paraplegia 17 ⁴⁸ ²⁴ ²⁷ ⁶⁸

Spg17 ⁴⁸ ²⁴

Spastic Paraplegia with Amyotrophy of Hands and Feet ⁴⁸

Autosomal Dominant Spastic Paraplegia Type 17 ⁴⁸

Silver Spastic Paraplegia Syndrome ⁴⁸

Silver Spastic Paraplegia ²⁴

Russell-Silver Syndrome ⁶⁸

Silver Syndrome ⁴⁸

Spg 17 ²⁴

Hsp17 ²⁴

Classifications:

MalaCards categories:
Global: Genetic diseases, Rare diseases, Metabolic diseases
Anatomical: Neuronal diseases, Eye diseases, Gastrointestinal diseases, Bone diseases, Mental diseases

See all MalaCards categories (disease lists)

Summaries for Spastic Paraplegia 17

Sources:
³⁶MalaCards
See all MalaCards sources

MalaCards based summary: Spastic Paraplegia 17, also known as spg17, is related to silver spastic paraplegia syndrome and der kaloustian mcintosh silver syndrome, and has symptoms including lower limb muscle weakness An important gene associated with Spastic Paraplegia 17 is BSCL2 (BSCL2, Seipin Lipid Droplet Biogenesis Associated).

Related Diseases for Spastic Paraplegia 17

Sources:
²⁰GeneAnalytics, ²¹GeneCards
See all MalaCards sources

Diseases in the Spastic Paraplegia 3a family:

Spastic Paraplegia 29, Autosomal Dominant	Spastic Paraplegia 63
Spastic Paraplegia 47, Autosomal Recessive	Spastic Paraplegia 23
Spastic Paraplegia 44, Autosomal Recessive	Spastic Paraplegia 74, Autosomal Recessive
Spastic Paraplegia 4, Autosomal Dominant	Spastic Paraplegia 31, Autosomal Dominant
Spastic Paraplegia 13, Autosomal Dominant	Spastic Paraplegia 30, Autosomal Recessive
Spastic Paraplegia 57, Autosomal Recessive	Spastic Paraplegia 42, Autosomal Dominant
Spastic Paraplegia 14, Autosomal Recessive	Spastic Paraplegia 38, Autosomal Dominant
Spastic Paraplegia 56, Autosomal Recessive	Spastic Paraplegia 72, Autosomal Recessive
Spastic Paraplegia 25, Autosomal Recessive	Spastic Paraplegia 48, Autosomal Recessive
Spastic Paraplegia 50, Autosomal Recessive	Spastic Paraplegia 53, Autosomal Recessive
Spastic Paraplegia 37, Autosomal Dominant	Spastic Paraplegia 54, Autosomal Recessive
Spastic Paraplegia 18, Autosomal Recessive	Spastic Paraplegia 5a, Autosomal Recessive
Spastic Paraplegia 8, Autosomal Dominant	Spastic Paraplegia 46, Autosomal Recessive
Spastic Paraplegia 19, Autosomal Dominant	Spastic Paraplegia 27, Autosomal Recessive
Spastic Paraplegia 64, Autosomal Recessive	Spastic Paraplegia 33, Autosomal Dominant
Spastic Paraplegia 9a, Autosomal Dominant	Spastic Paraplegia 9b, Autosomal Recessive
Spastic Paraplegia 45, Autosomal Recessive	Spastic Paraplegia 41, Autosomal Dominant
Spastic Paraplegia 26, Autosomal Recessive	Spastic Paraplegia 10, Autosomal Dominant
Spastic Paraplegia 36, Autosomal Dominant	Spastic Paraplegia 55, Autosomal Recessive
Spastic Paraplegia 24, Autosomal Recessive	Spastic Paraplegia 3a, Autosomal Dominant
Spastic Paraplegia 52, Autosomal Recessive	Spastic Paraplegia 32, Autosomal Recessive
Spastic Paraplegia 28, Autosomal Recessive	Spastic Paraplegia 15, Autosomal Recessive
Spastic Paraplegia 49, Autosomal Recessive	Spastic Paraplegia 6, Autosomal Dominant
Spastic Paraplegia 11, Autosomal Recessive	Spastic Paraplegia 51, Autosomal Recessive
Spastic Paraplegia 61, Autosomal Recessive	Spastic Paraplegia 35, Autosomal Recessive
Spastic Paraplegia 7, Autosomal Recessive	Spastic Paraplegia 39, Autosomal Recessive
Spastic Paraplegia 43, Autosomal Recessive	Spastic Paraplegia 12, Autosomal Dominant
Spastic Paraplegia 73, Autosomal Dominant	Hereditary Spastic Paraplegia
Hereditary Spastic Paraplegia 3a	Hereditary Spastic Paraplegia 51
Hereditary Spastic Paraplegia 62	Hereditary Spastic Paraplegia 72
Hereditary Spastic Paraplegia 75	Hereditary Spastic Paraplegia 76
Hereditary Spastic Paraplegia 77	Spastic Paraplegia 4
Spastic Paraplegia 8	Spastic Paraplegia 11
Spastic Paraplegia 1	Spastic Paraplegia 10
Spastic Paraplegia 12	Spastic Paraplegia 13
Spastic Paraplegia 14	Spastic Paraplegia 15
Spastic Paraplegia 16	spastic paraplegia 17
Spastic Paraplegia 18	Spastic Paraplegia 19
Spastic Paraplegia 24	Spastic Paraplegia 25
Spastic Paraplegia 26	Spastic Paraplegia 29
Spastic Paraplegia 3	Spastic Paraplegia 31
Spastic Paraplegia 32	Spastic Paraplegia 39
Spastic Paraplegia 51	Spastic Paraplegia 5a
Spastic Paraplegia 5b	Spastic Paraplegia 6
Spastic Paraplegia 9	Spastic Paraplegia 28
Spastic Paraplegia 30	Spastic Paraplegia 33
Spastic Paraplegia 35	Spastic Paraplegia 42
Spastic Paraplegia 43	Spastic Paraplegia 45
Spastic Paraplegia 46	Spastic Paraplegia 47
Spastic Paraplegia 48	Spastic Paraplegia 49
Spastic Paraplegia 50	Spastic Paraplegia 52
Spastic Paraplegia 53	Spastic Paraplegia 54
Spastic Paraplegia 55	Spastic Paraplegia 56
Spastic Paraplegia 57	Spastic Paraplegia 59
Spastic Paraplegia 61	Spastic Paraplegia 62
Spastic Paraplegia 64	Spastic Paraplegia 66
Spastic Paraplegia 72	Spastic Paraplegia 75
Spastic Paraplegia 76	Spastic Paraplegia 44
Autosomal Recessive Spastic Paraplegia Type 60	Autosomal Recessive Spastic Paraplegia Type 59
Autosomal Recessive Spastic Paraplegia Type 68	Autosomal Recessive Spastic Paraplegia Type 69
Autosomal Recessive Spastic Paraplegia Type 70	Autosomal Recessive Spastic Paraplegia Type 71
Autosomal Recessive Spastic Paraplegia Type 66	Autosomal Recessive Spastic Paraplegia Type 67
Spastic Paraplegia 78, Autosomal Recessive

Diseases related to Spastic Paraplegia 17 via text searches within MalaCards or GeneCards Suite gene sharing:

id	Related Disease	Score	Top Affiliating Genes
1	silver spastic paraplegia syndrome	11.9
2	der kaloustian mcintosh silver syndrome	11.8
3	silver-russell syndrome	11.7
4	chromosome 11p15.5-related russell-silver syndrome	11.7
5	chromosome 7-related russell-silver syndrome	11.7
6	ceroid lipofuscinosis, neuronal, 13, kufs type	9.8	BSCL2, CDKN1C
7	paraplegia	9.8
8	spasticity	9.8
9	spastic paraplegia 39	9.7	BSCL2, CDKN1C

Graphical network of diseases related to Spastic Paraplegia 17:

Symptoms & Phenotypes for Spastic Paraplegia 17

Sources:
⁶⁸UMLS
See all MalaCards sources

UMLS symptoms related to Spastic Paraplegia 17:

lower limb muscle weakness

Drugs & Therapeutics for Spastic Paraplegia 17

Sources:
⁴ClinicalTrials
See all MalaCards sources

Interventional clinical trials:

id	Name	Status	NCT ID	Phase
1	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	Recruiting	NCT01793168

Search NIH Clinical Center for Spastic Paraplegia 17

Genetic Tests for Spastic Paraplegia 17

Sources:
²⁴GeneTests, ²⁷GTR
See all MalaCards sources

Genetic tests related to Spastic Paraplegia 17:

id	Genetic test	Affiliating Genes
1	Spastic Paraplegia 17²⁷ ²⁴	BSCL2

Anatomical Context for Spastic Paraplegia 17

Publications for Spastic Paraplegia 17

Sources:
⁵⁷PubMed
See all MalaCards sources

Articles related to Spastic Paraplegia 17:

id	Title	Authors	Year
1	Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17. (18585921)	Ito D.... Suzuki N.	2008

Genes related to Spastic Paraplegia 17

Sources:
²¹GeneCards, ²⁴GeneTests
See all MalaCards sources

Genes related to Spastic Paraplegia 17 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	BSCL2	BSCL2, Seipin Lipid Droplet Biogenesis Associated	150.08	Genetic Tests ²⁴ GeneCards inferred via : Disorders, Publications, Gene name, Variants (show sections)
2	CDKN1C	Cyclin Dependent Kinase Inhibitor 1C	18.70	GeneCards inferred via : Disorders (show sections)