MCID: SPS054
MIFTS: 16

Spastic Paraplegia 35 malady

Genetic diseases, Rare diseases, Neuronal diseases, Mental diseases, Fetal diseases, Gastrointestinal diseases, Bone diseases, Metabolic diseases, Eye diseases categories

Summaries for Spastic Paraplegia 35

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MalaCards based summary: Spastic Paraplegia 35 is related to fatty acid hydroxylase-associated neurodegeneration. An important gene associated with Spastic Paraplegia 35 is FA2H (fatty acid 2-hydroxylase).

Aliases & Classifications for Spastic Paraplegia 35

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Spastic Paraplegia 35, Aliases & Descriptions:

Name: Spastic Paraplegia 35 21 23 61


Classifications:



Related Diseases for Spastic Paraplegia 35

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Diseases in the Spastic Paraplegia 1 family:

Hereditary Spastic Paraplegia Spastic Paraplegia 3a
Spastic Paraplegia 4 Spastic Paraplegia 7
Spastic Paraplegia 8 Spastic Paraplegia 11
Spastic Paraplegia 10 Spastic Paraplegia 12
Spastic Paraplegia 13 Spastic Paraplegia 14
Spastic Paraplegia 15 Spastic Paraplegia 16
Spastic Paraplegia 17 Spastic Paraplegia 18
Spastic Paraplegia 19 Spastic Paraplegia 2
Spastic Paraplegia 23 Spastic Paraplegia 24
Spastic Paraplegia 25 Spastic Paraplegia 26
Spastic Paraplegia 29 Spastic Paraplegia 3
Spastic Paraplegia 31 Spastic Paraplegia 39
Spastic Paraplegia 51 Spastic Paraplegia 5a
Spastic Paraplegia 5b Spastic Paraplegia 6
Spastic Paraplegia 9 Spastic Paraplegia 33
Spastic Paraplegia 42 Spastic Paraplegia 30
Spastic Paraplegia 48 spastic paraplegia 35
Spastic Paraplegia 44 Spastic Paraplegia 29, Autosomal Dominant
Spastic Paraplegia 63 Spastic Paraplegia 47, Autosomal Recessive
Spastic Paraplegia 44, Autosomal Recessive Spastic Paraplegia 13, Autosomal Dominant
Spastic Paraplegia 30, Autosomal Recessive Spastic Paraplegia 57, Autosomal Recessive
Spastic Paraplegia 42, Autosomal Dominant Spastic Paraplegia 14, Autosomal Recessive
Spastic Paraplegia 38, Autosomal Dominant Spastic Paraplegia 56, Autosomal Recessive
Spastic Paraplegia 72, Autosomal Recessive Spastic Paraplegia 72, Autosomal Dominant
Spastic Paraplegia 25, Autosomal Recessive Spastic Paraplegia 48, Autosomal Recessive
Spastic Paraplegia 50, Autosomal Recessive Spastic Paraplegia 53, Autosomal Recessive
Spastic Paraplegia 37, Autosomal Dominant Spastic Paraplegia 54, Autosomal Recessive
Spastic Paraplegia 18, Autosomal Recessive Spastic Paraplegia 5a, Autosomal Recessive
Spastic Paraplegia 46, Autosomal Recessive Spastic Paraplegia 19, Autosomal Dominant
Spastic Paraplegia 27, Autosomal Recessive Spastic Paraplegia 9, Autosomal Dominant
Spastic Paraplegia 64 Spastic Paraplegia 33, Autosomal Dominant
Spastic Paraplegia 45 Spastic Paraplegia 45, Autosomal Recessive
Spastic Paraplegia 41, Autosomal Dominant Spastic Paraplegia 26, Autosomal Recessive
Spastic Paraplegia 10, Autosomal Dominant Spastic Paraplegia 36, Autosomal Dominant
Spastic Paraplegia 55, Autosomal Recessive Spastic Paraplegia 24, Autosomal Recessive
Spastic Paraplegia 3a, Autosomal Dominant Spastic Paraplegia 52, Autosomal Recessive
Spastic Paraplegia 32, Autosomal Recessive Spastic Paraplegia 28, Autosomal Recessive
Spastic Paraplegia 49, Autosomal Recessive Spastic Paraplegia 6, Autosomal Dominant
Spastic Paraplegia 61, Autosomal Recessive Spastic Paraplegia 7, Autosomal Recessive
Spastic Paraplegia 39, Autosomal Recessive Spastic Paraplegia 43, Autosomal Recessive
Spastic Paraplegia 12, Autosomal Dominant Autosomal Recessive Spastic Paraplegia Type 62
Autosomal Recessive Spastic Paraplegia Type 60 Autosomal Recessive Spastic Paraplegia Type 59
Autosomal Recessive Spastic Paraplegia Type 68 Autosomal Recessive Spastic Paraplegia Type 69
Autosomal Recessive Spastic Paraplegia Type 70 Autosomal Recessive Spastic Paraplegia Type 71
Autosomal Recessive Spastic Paraplegia Type 66 Autosomal Recessive Spastic Paraplegia Type 67

Diseases related to Spastic Paraplegia 35 via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1fatty acid hydroxylase-associated neurodegeneration10.6

Symptoms for Spastic Paraplegia 35

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Drugs & Therapeutics for Spastic Paraplegia 35

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Drug clinical trials:

Search ClinicalTrials for Spastic Paraplegia 35

Search NIH Clinical Center for Spastic Paraplegia 35

Genetic Tests for Spastic Paraplegia 35

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Genetic tests related to Spastic Paraplegia 35:

id Genetic test Affiliating Genes
1 Spastic Paraplegia 3521 23

Anatomical Context for Spastic Paraplegia 35

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Animal Models for Spastic Paraplegia 35 or affiliated genes

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Publications for Spastic Paraplegia 35

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Variations for Spastic Paraplegia 35

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Clinvar genetic disease variations for Spastic Paraplegia 35:

7
id Gene Name Type Significance SNP ID Assembly Location
1FA2HNM_024306.4(FA2H): c.103G> T (p.Asp35Tyr)single nucleotide variantPathogenicrs121918217GRCh37Chr 16, 74808551: 74808551
2FA2HNM_024306.4(FA2H): c.703C> T (p.Arg235Cys)single nucleotide variantPathogenicrs387907039GRCh37Chr 16, 74752969: 74752969
3FA2HNM_024306.4(FA2H): c.460C> T (p.Arg154Cys)single nucleotide variantPathogenicrs387907040GRCh37Chr 16, 74761188: 74761188
4FA2HNM_024306.4(FA2H): c.707T> C (p.Phe236Ser)single nucleotide variantPathogenicrs387907172GRCh37Chr 16, 74752965: 74752965

Expression for genes affiliated with Spastic Paraplegia 35

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Expression patterns in normal tissues for genes affiliated with Spastic Paraplegia 35

Search GEO for disease gene expression data for Spastic Paraplegia 35.

Pathways for genes affiliated with Spastic Paraplegia 35

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Compounds for genes affiliated with Spastic Paraplegia 35

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GO Terms for genes affiliated with Spastic Paraplegia 35

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Products for genes affiliated with Spastic Paraplegia 35

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Spastic Paraplegia 35

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet