MCID: SPR016
MIFTS: 37

Spermatic Cord Torsion malady

Category: Reproductive diseases

Aliases & Classifications for Spermatic Cord Torsion

About this section

Aliases & Descriptions for Spermatic Cord Torsion:

Name: Spermatic Cord Torsion 10 12 36 65
Torsion of Testicle 10
 
Testicular Torsion 10
Torsion of Testis 10

Classifications:



External Ids:

Disease Ontology10 DOID:11996
ICD9CM29 608.2, 608.20
MeSH36 D013086
NCIt42 C26885
UMLS65 C0037856

Summaries for Spermatic Cord Torsion

About this section
Wikipedia:68 Testicular torsion occurs when the spermatic cord (from which the testicle is suspended) twists, cutting... more...

MalaCards based summary: Spermatic Cord Torsion, also known as torsion of testicle, is related to hodgkin lymphoma and lymphoma. An important gene associated with Spermatic Cord Torsion is TWIST1 (Twist Family BHLH Transcription Factor 1), and among its related pathways are Selenium Metabolism and Selenoproteins and Detoxification of Reactive Oxygen Species. Affiliated tissues include testis, ovary and breast, and related mouse phenotypes are embryo and cellular.

Related Diseases for Spermatic Cord Torsion

About this section

Graphical network of the top 20 diseases related to Spermatic Cord Torsion:



Diseases related to spermatic cord torsion

Symptoms for Spermatic Cord Torsion

About this section

Drugs & Therapeutics for Spermatic Cord Torsion

About this section

Drugs for Spermatic Cord Torsion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Androgens1162
2Hormones11748
3Follicle Stimulating Hormone151
4Hormones, Hormone Substitutes, and Hormone Antagonists9988
5Estrogens2144
6Hormone Antagonists10002

Interventional clinical trials:

idNameStatusNCT IDPhase
1Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular TorsionRecruitingNCT01812109
2Quality of Life Among Testicular Cancer SurvivorsRecruitingNCT02304575
3Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish MenActive, not recruitingNCT00150163
4Diagnosis of Acute Appendicitis, Ovary Torsion and Inflammation, and Testicular Torsion and Inflammation by Infrared ThermographyNot yet recruitingNCT01079650

Search NIH Clinical Center for Spermatic Cord Torsion


Cochrane evidence based reviews: spermatic cord torsion

Genetic Tests for Spermatic Cord Torsion

About this section

Anatomical Context for Spermatic Cord Torsion

About this section

MalaCards organs/tissues related to Spermatic Cord Torsion:

33
Testis, Ovary, Breast, Endothelial, Lung, Colon, Myeloid

Animal Models for Spermatic Cord Torsion or affiliated genes

About this section

MGI Mouse Phenotypes related to Spermatic Cord Torsion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.0BMP1, GPX4, RFX2, SPTAN1, TWIST1
2MP:00053847.4CAT, CATSPER1, GPX1, GPX4, NOS3, SPTAN1
3MP:00107687.0BMP1, CAT, GPX1, GPX4, NOS3, SPTAN1

Publications for Spermatic Cord Torsion

About this section

Articles related to Spermatic Cord Torsion:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Ptosis Repair in Ocular Myasthenia Gravis. (27191622)
2016
2
HDAC1 promoted migration and invasion binding with TCF12 by promoting EMT progress in gallbladder cancer. (27092878)
2016
3
Relationship of DNA Methylation and Gene Expression in Idiopathic Pulmonary Fibrosis (IPF). (25333685)
2014
4
MYC and MXI1 protein expression: potential prognostic significance in women with breast cancer in China. (24685915)
2014
5
The structural and functional organization of the podocyte filtration slits is regulated by Tjp1/ZO-1. (25184792)
2014
6
Lipid peroxidation markers in adult attention deficit hyperactivity disorder: new findings for oxidative stress. (23680468)
2013
7
L32. ANCA vasculitis over the world. What do we learn from country differences? (23481365)
2013
8
Onset and progression of peripapillary retinal nerve fiber layer (RNFL) retardance changes occur earlier than RNFL thickness changes in experimental glaucoma. (23847322)
2013
9
Helicobacter pylori-Induced Chronic Gastritis and Assessing Risks for Gastric Cancer. (23983680)
2013
10
Excision-repair-cross-complement-1 protein as a prognostic factor in patients with advanced non-small cell lung cancer treated with platinum-based first-line chemotherapy. (23993732)
2013
11
Percutaneous patent foramen ovale closure in a patient with inferior vena cava filter. (24297724)
2013
12
Pre-treatment waking cortisol response and vulnerability to interferon I+ induced depression. (22571879)
2012
13
Identification of intercellular cell adhesion molecule 1 (ICAM-1) as a hypoglycosylation marker in congenital disorders of glycosylation cells. (22496445)
2012
14
Outcome of protracted hypoparathyroidism after total thyroidectomy. (20730856)
2010
15
Association of serum osteoprotegerin with left ventricular mass in African American adults with hypertension. (20339356)
2010
16
Rapid flow cytometric detection of aberrant cytoplasmic localization of nucleophosmin (NPMc) indicating mutant NPM1 gene in acute myeloid leukemia. (20724983)
2010
17
Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis. (19856479)
2009
18
Ex vivo expansion of tumor specific lymphocytes with IL-15 and IL-21 for adoptive immunotherapy in melanoma. (19501956)
2009
19
Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. (19305393)
2009
20
Sulindac induces apoptotic cell death in susceptible human breast cancer cells through, at least in part, inhibition of IKKbeta. (19526344)
2009
21
Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. (19304780)
2009
22
Are laboratories reporting serum quantitative hCG results correctly? (18375490)
2008
23
Allergic contact cheilitis due to geraniol in food. (17343631)
2007
24
Follicular dendritic cell tumor of the gastrointestinal tract: Report of a rare neoplasm and literature review. (16564140)
2006
25
Subacute sclerosing panencephalitis presenting with Balint's syndrome. (16376513)
2006
26
Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice? (15966731)
2005
27
Corticotropin-releasing factor 1 receptor-mediated mechanisms inhibit colonic hypersensitivity in rats. (15916629)
2005
28
CLAC binds to aggregated Abeta and Abeta fragments, and attenuates fibril elongation. (16300410)
2005
29
Dominant cone and cone-rod dystrophies: functional analysis of mutations in retGC1 and GCAP1. (14750595)
2004
30
VIGR -- a novel inducible adhesion family G-protein coupled receptor in endothelial cells. (15225624)
2004
31
Differential effects of iron deficiency and underfeeding on serum levels of interleukin-10, interleukin-12p40, and interferon-gamma in mice. (15050607)
2004
32
Association analysis between anterior-pharynx defective-1 genes polymorphisms and Alzheimer's disease. (12972157)
2003
33
Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets. (12837764)
2003
34
Association and linkage disequilibrium between a functional polymorphism of the dopamine-2 receptor gene and schizophrenia in a genetically homogeneous Portuguese population. (12399954)
2002
35
Identification of a novel regulatory element in the human interleukin 1 alpha (IL-1alpha) gene promoter. (12453471)
2002
36
Cholesteryl ester transfer protein and atherosclerosis in Japanese subjects: a study based on coronary angiography. (11689217)
2001
37
Corticobasal degeneration presenting with nonfluent primary progressive aphasia: a clinicopathological study. (11166789)
2001
38
Phase I trial of 96-hour continuous infusion of dexrazoxane in patients with advanced malignancies. (11410492)
2001
39
Role of interleukin-8 in community-acquired pneumonia: relation to microbial load and pulmonary function. (9108184)
1997
40
Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy. (9151680)
1997
41
Neural crest and multiple endocrinopathies]. (9074721)
1996
42
Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells. (7489748)
1995
43
Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease. (8104689)
1993
44
Recognition of tRNAs by aminoacyl-tRNA synthetases. (8422978)
1993
45
Orbital plexiform neurofibroma. (8025053)
1993
46
Analysis of eye lens-specific genes in congenital hereditary cataracts and microphthalmia of the miniature schnauzer dog. (1869417)
1991
47
Design of DNA-binding peptides based on the leucine zipper motif. (2389143)
1990
48
Gene polymorphism identified by PvuII in familial lipoprotein lipase deficiency. (2574035)
1989
49
Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia. (2901442)
1988
50
Increased fetal hemoglobin production in a child with congenital hyperinsulinism. (2438395)
1987

Variations for Spermatic Cord Torsion

About this section

Expression for genes affiliated with Spermatic Cord Torsion

About this section
Search GEO for disease gene expression data for Spermatic Cord Torsion.

Pathways for genes affiliated with Spermatic Cord Torsion

About this section

GO Terms for genes affiliated with Spermatic Cord Torsion

About this section

Biological processes related to Spermatic Cord Torsion according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1lipoxygenase pathwayGO:001937210.2GPX1, GPX4
2UV protectionGO:000965010.0CAT, GPX1
3purine nucleotide catabolic processGO:00061959.9CAT, GPX1
4triglyceride metabolic processGO:00066419.8CAT, GPX1
5nucleobase-containing small molecule metabolic processGO:00550869.7CAT, GPX1
6purine nucleobase metabolic processGO:00061449.7CAT, GPX1
7osteoblast differentiationGO:00016499.6CAT, TWIST1
8arachidonic acid metabolic processGO:00193699.6GPX1, GPX4
9response to reactive oxygen speciesGO:00003029.6CAT, GPX1
10cellular response to growth factor stimulusGO:00713639.5CAT, TWIST1
11ossificationGO:00015039.5BMP1, TWIST1
12cellular oxidant detoxificationGO:00988699.2CAT, GPX1, GPX4
13response to oxidative stressGO:00069798.8CAT, GPX1, GPX4

Sources for Spermatic Cord Torsion

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet