MCID: SPR016
MIFTS: 31

Spermatic Cord Torsion malady

Category: Reproductive diseases

Aliases & Classifications for Spermatic Cord Torsion

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Aliases & Descriptions for Spermatic Cord Torsion:

Name: Spermatic Cord Torsion 11 13 37 66
Torsion of Testicle 11
 
Testicular Torsion 11
Torsion of Testis 11

Classifications:



External Ids:

Disease Ontology11 DOID:11996
ICD9CM30 608.2, 608.20
MeSH37 D013086
NCIt43 C26885

Summaries for Spermatic Cord Torsion

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Wikipedia:69 Testicular torsion occurs when the spermatic cord (from which the testicle is suspended) twists, cutting... more...

MalaCards based summary: Spermatic Cord Torsion, also known as torsion of testicle, is related to orchitis and ischemia, and has symptoms including pain in testicle, epididymal tenderness and spermatic cord pain. An important gene associated with Spermatic Cord Torsion is TWIST1 (Twist Family BHLH Transcription Factor 1), and among its related pathways are AGE/RAGE pathway and VEGF Pathway (Tocris). Affiliated tissues include testis, ovary and testes, and related mouse phenotypes are craniofacial and skeleton.

Related Diseases for Spermatic Cord Torsion

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Diseases related to Spermatic Cord Torsion via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1orchitis10.1
2ischemia10.1
3sertoli cell tumor10.1
4hydrocele10.1
5epididymo-orchitis10.0
6urinary bladder cancer10.0BMP1, NOS3
7cryptorchidism10.0
8testicular infarct10.0
9hypoxia10.0
10prostate adenocarcinoma9.9CATSPER1, NOS3, TWIST1
11purpura9.8
12cohen syndrome9.8
13androgen insensitivity9.8
14gender identity disorder9.7CASP3, NOS3
15ulcerative colitis9.5CASP3, SPTAN1
16brain meningioma9.3CASP3, SPTAN1
17female reproductive organ cancer6.7BMP1, C1R, CASP3, CATSPER1, INSL3, NOS3

Graphical network of diseases related to Spermatic Cord Torsion:



Diseases related to spermatic cord torsion

Symptoms for Spermatic Cord Torsion

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UMLS symptoms related to Spermatic Cord Torsion:


pain in testicle, epididymal tenderness, spermatic cord pain

Drugs & Therapeutics for Spermatic Cord Torsion

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular TorsionRecruitingNCT01812109
2Quality of Life Among Testicular Cancer SurvivorsRecruitingNCT02304575
3Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish MenActive, not recruitingNCT00150163
4Diagnosis of Acute Appendicitis, Ovary Torsion and Inflammation, and Testicular Torsion and Inflammation by Infrared ThermographyNot yet recruitingNCT01079650

Search NIH Clinical Center for Spermatic Cord Torsion


Cochrane evidence based reviews: spermatic cord torsion

Genetic Tests for Spermatic Cord Torsion

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Anatomical Context for Spermatic Cord Torsion

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MalaCards organs/tissues related to Spermatic Cord Torsion:

34
Testis, Ovary, Testes

Animal Models for Spermatic Cord Torsion or affiliated genes

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MGI Mouse Phenotypes related to Spermatic Cord Torsion:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.5BMP1, CASP3, SPTAN1, TWIST1
2MP:00053907.8BMP1, CASP3, INSL3, NOS3, TWIST1
3MP:00053897.6CASP3, CATSPER1, INSL3, NOS3, RFX2

Publications for Spermatic Cord Torsion

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Articles related to Spermatic Cord Torsion:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Missed spermatic cord torsion in an old man. (24175049)
2013
2
Sertoli cell tumors associated with feminizing syndrome and spermatic cord torsion in two cryptorchid dogs. (22705745)
2012
3
Subsequent alterations in the contractile property ofA the vas deferens according to duration of spermatic cord torsion. (21890132)
2011
4
Spermatic cord knot: a clinical finding in patients with spermatic cord torsion. (22190915)
2011
5
The morphological evaluation of ipsilateral and contralateral vasa deferentia in a rat model of unilateral spermatic cord torsion. (19921213)
2010
6
Experimental unilateral spermatic cord torsion: the effect of polypolymerase enzyme inhibitor on histopathological and biochemical changes in the early and late periods in the ipsilateral and contralateral testicles. (20579694)
2010
7
Protective effect of alpha-lipoic acid in experimental spermatic cord torsion. (17112702)
2007
8
Unilateral spermatic cord torsion without ipsilateral spermatogenetic material: effects on testicular blood flow and fertility potential. (14579109)
2004
9
Spermatic cord torsion with preserved testis perfusion: initial anatomical observations. (15538271)
2004
10
Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury. (15051328)
2004
11
Sonographic diagnosis of acute spermatic cord torsion. Rotation of the cord: a key to the diagnosis. (12107581)
2002
12
The effect of methylene blue on histological damage after spermatic cord torsion in a rat model. (11446854)
2001
13
Spermatic cord torsion after testicular fixation. A different surgical approach and a revision of current techniques. (11807671)
2001
14
Noradrenaline and nitrite-nitrate concentrations in the contralateral testes during ipsilateral spermatic cord torsion in the presence or absence of a testis and epididymis. (10368208)
1999
15
DNA flow cytometry reveals depressed spermatogenetic activity in the contralateral testis within 24 h of ipsilateral spermatic cord torsion independently of the presence of the testis and epididymis. (9748690)
1998
16
Influence of experimental spermatic cord torsion on the contralateral testis in rats. Evaluation of tissue free oxygen radical scavenger enzyme levels. (9253119)
1997
17
Serum creatine kinase enzyme levels in the early diagnosis of spermatic cord torsion. (9008324)
1996
18
Is ipsilateral testis mandatory for the occurrence of contralateral intratesticular biochemical changes indicative of hypoxia after unilateral spermatic cord torsion? (8529740)
1995
19
Spermatic cord torsion in adults. (7817170)
1994
20
Variability of ischemia during spermatic cord torsion in the rat. (8126796)
1994
21
Special imaging casebook. Neonatal spermatic cord torsion and testicular infarction. (7830162)
1994
22
Is ipsilateral testis mandatory for contralateral testicular deterioration encountered following spermatic cord torsion? (7974914)
1994
23
Spermatic cord torsion in an infant receiving human chorionic gonadotropin. (8103805)
1993
24
Spermatic cord torsion: loss of spermatogenesis despite return of blood flow. (8373967)
1993
25
Sonographic appearance of the torsion knot in spermatic cord torsion. (1414769)
1992
26
The effect of polyethylene glycol-superoxide dismutase administration on histological damage following spermatic cord torsion. (1640536)
1992
27
Color Doppler ultrasound compared to a radionuclide scanning of spermatic cord torsion in a canine model. (1846434)
1991
28
Spermatic cord torsion: effects of cyclosporine and prednisone on fertility and the contralateral testis in the rat. (2254174)
1990
29
Spermatic cord torsion. Contralateral testicular degeneration at various ages in the rat. (2086577)
1990
30
The effect of various degrees of unilateral spermatic cord torsion on fertility in the rat. (2374208)
1990
31
Intrauterine spermatic cord torsion in the newborn: sonographic and pathologic correlation. (2243983)
1990
32
Spermatic cord torsion. (3813629)
1987
33
Testicular salvage following spermatic cord torsion. (3559866)
1987
34
Spermatic cord torsion in the neonate. (3476079)
1987
35
Spermatic cord torsion. (3717988)
1986
36
Histopathology of prepubertal rat testes subjected to various durations of spermatic cord torsion. (3944017)
1986
37
Spermatic cord torsion: diagnostic limitations. (2999690)
1985
38
Histological changes occurring in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion. (3989935)
1985
39
The effect of prepubertal spermatic cord torsion on subsequent fertility in rats. (6715258)
1984
40
Autoantibodies against Leydig cells in patients after spermatic cord torsion. (6362937)
1984
41
Spermatic cord torsion in the neonate. (6827663)
1983
42
Histological study of the removed testes of patients after acute monolateral spermatic cord torsion. (6666858)
1983
43
Spermatic cord torsion and Sertoli cell tumor in a dog. (6138340)
1983
44
Spermatic cord torsion following previous surgical fixation. (7143612)
1982
45
Immunological and clinical study of patients after spermatic cord torsion. (7039415)
1982
46
Spermatic cord torsion in a dog. (7207448)
1981
47
Bilateral spermatic cord torsion in the neonate. (7354546)
1980
48
Bilaterally enlarged testicles in a newborn: an atypical presentation of intrauterine spermatic cord torsion. (7191631)
1980
49
Bilateral spermatic cord torsion in the neonate. (7420615)
1980
50
Spermatic cord torsion in the newborn. (1273783)
1976

Variations for Spermatic Cord Torsion

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Expression for genes affiliated with Spermatic Cord Torsion

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Search GEO for disease gene expression data for Spermatic Cord Torsion.

Pathways for genes affiliated with Spermatic Cord Torsion

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Pathways related to Spermatic Cord Torsion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3CASP3, NOS3
2
Show member pathways
9.3CASP3, NOS3
39.1C1R, CASP3

GO Terms for genes affiliated with Spermatic Cord Torsion

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Sources for Spermatic Cord Torsion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet