MCID: SPR016
MIFTS: 30

Spermatic Cord Torsion malady

Category: Reproductive diseases

Aliases & Classifications for Spermatic Cord Torsion

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Aliases & Descriptions for Spermatic Cord Torsion:

Name: Spermatic Cord Torsion 11 39 13 68
Torsion of Testicle 11
 
Testicular Torsion 11
Torsion of Testis 11

Classifications:



External Ids:

Disease Ontology11 DOID:11996
ICD9CM32 608.2, 608.20
MeSH39 D013086
NCIt45 C26885

Summaries for Spermatic Cord Torsion

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Wikipedia:71 Testicular torsion occurs when the spermatic cord (from which the testicle is suspended) twists, cutting... more...

MalaCards based summary: Spermatic Cord Torsion, also known as torsion of testicle, is related to orchitis and ischemia. An important gene associated with Spermatic Cord Torsion is CATSPER1 (Cation Channel Sperm Associated 1), and among its related pathways are AGE/RAGE pathway and Pertussis. Affiliated tissues include testis and testes, and related mouse phenotype cellular.

Related Diseases for Spermatic Cord Torsion

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Diseases related to Spermatic Cord Torsion via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1orchitis10.0
2ischemia10.0
3sertoli cell tumor10.0
4charcot-marie-tooth disease, axonal, type 2w10.0BMP1, C1R
5retroperitoneal sarcoma10.0CASP3, NOS3
6urea cycle disorder10.0CASP3, SPTAN1
7hydrocele10.0
8epididymo-orchitis9.9
9renal-hepatic-pancreatic dysplasia9.9INSL3, TWIST1
10breast reconstruction9.8CASP3, SPTAN1
11cryptorchidism9.8
12testicular infarct9.8
13hypoxia9.8
14purpura9.7
15splenic disease9.7CATSPER1, INSL3, NOS3, TWIST1
16tracheal lymphoma8.7BMP1, C1R, CASP3, CATSPER1, INSL3, NOS3

Graphical network of diseases related to Spermatic Cord Torsion:



Diseases related to spermatic cord torsion

Symptoms & Phenotypes for Spermatic Cord Torsion

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MGI Mouse Phenotypes related to Spermatic Cord Torsion according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.1CASP3, CATSPER1, INSL3, NOS3, RFX2, SPTAN1

Drugs & Therapeutics for Spermatic Cord Torsion

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Drugs for Spermatic Cord Torsion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Hormones, Hormone Substitutes, and Hormone Antagonists13168
2Hormones14415
3Hormone Antagonists13180
4Androgens1321
5Estrogens2542
6Follicle Stimulating Hormone167

Interventional clinical trials:

idNameStatusNCT IDPhase
1Diagnosis of Acute Appendicitis, Ovary Torsion and Inflammation, and Testicular Torsion and Inflammation by Infrared ThermographyUnknown statusNCT01079650
2Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish MenUnknown statusNCT00150163
3Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular TorsionRecruitingNCT01812109
4Quality of Life Among Testicular Cancer SurvivorsRecruitingNCT02304575

Search NIH Clinical Center for Spermatic Cord Torsion


Cochrane evidence based reviews: spermatic cord torsion

Genetic Tests for Spermatic Cord Torsion

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Anatomical Context for Spermatic Cord Torsion

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MalaCards organs/tissues related to Spermatic Cord Torsion:

36
Testis, Testes

Publications for Spermatic Cord Torsion

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Articles related to Spermatic Cord Torsion:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Missed spermatic cord torsion in an old man. (24175049)
2013
2
Sertoli cell tumors associated with feminizing syndrome and spermatic cord torsion in two cryptorchid dogs. (22705745)
2012
3
Subsequent alterations in the contractile property ofA the vas deferens according to duration of spermatic cord torsion. (21890132)
2011
4
Spermatic cord knot: a clinical finding in patients with spermatic cord torsion. (22190915)
2011
5
Experimental unilateral spermatic cord torsion: the effect of polypolymerase enzyme inhibitor on histopathological and biochemical changes in the early and late periods in the ipsilateral and contralateral testicles. (20579694)
2010
6
The morphological evaluation of ipsilateral and contralateral vasa deferentia in a rat model of unilateral spermatic cord torsion. (19921213)
2010
7
Protective effect of alpha-lipoic acid in experimental spermatic cord torsion. (17112702)
2007
8
Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury. (15051328)
2004
9
Spermatic cord torsion with preserved testis perfusion: initial anatomical observations. (15538271)
2004
10
Unilateral spermatic cord torsion without ipsilateral spermatogenetic material: effects on testicular blood flow and fertility potential. (14579109)
2004
11
Sonographic diagnosis of acute spermatic cord torsion. Rotation of the cord: a key to the diagnosis. (12107581)
2002
12
Spermatic cord torsion after testicular fixation. A different surgical approach and a revision of current techniques. (11807671)
2001
13
The effect of methylene blue on histological damage after spermatic cord torsion in a rat model. (11446854)
2001
14
Noradrenaline and nitrite-nitrate concentrations in the contralateral testes during ipsilateral spermatic cord torsion in the presence or absence of a testis and epididymis. (10368208)
1999
15
DNA flow cytometry reveals depressed spermatogenetic activity in the contralateral testis within 24 h of ipsilateral spermatic cord torsion independently of the presence of the testis and epididymis. (9748690)
1998
16
Influence of experimental spermatic cord torsion on the contralateral testis in rats. Evaluation of tissue free oxygen radical scavenger enzyme levels. (9253119)
1997
17
Acute spermatic cord torsion alters the microcirculation of the contralateral testis. (7490885)
1996
18
Serum creatine kinase enzyme levels in the early diagnosis of spermatic cord torsion. (9008324)
1996
19
Is ipsilateral testis mandatory for the occurrence of contralateral intratesticular biochemical changes indicative of hypoxia after unilateral spermatic cord torsion? (8529740)
1995
20
Spermatic cord torsion in adults. (7817170)
1994
21
Is ipsilateral testis mandatory for contralateral testicular deterioration encountered following spermatic cord torsion? (7974914)
1994
22
Variability of ischemia during spermatic cord torsion in the rat. (8126796)
1994
23
Special imaging casebook. Neonatal spermatic cord torsion and testicular infarction. (7830162)
1994
24
Spermatic cord torsion: loss of spermatogenesis despite return of blood flow. (8373967)
1993
25
Spermatic cord torsion in an infant receiving human chorionic gonadotropin. (8103805)
1993
26
The alterations of cellular metabolism in the contralateral testis following spermatic cord torsion in rats. (8326602)
1993
27
Sonographic appearance of the torsion knot in spermatic cord torsion. (1414769)
1992
28
The effect of polyethylene glycol-superoxide dismutase administration on histological damage following spermatic cord torsion. (1640536)
1992
29
Color Doppler ultrasound compared to a radionuclide scanning of spermatic cord torsion in a canine model. (1846434)
1991
30
Spermatic cord torsion. Contralateral testicular degeneration at various ages in the rat. (2086577)
1990
31
Intrauterine spermatic cord torsion in the newborn: sonographic and pathologic correlation. (2243983)
1990
32
The effect of various degrees of unilateral spermatic cord torsion on fertility in the rat. (2374208)
1990
33
Spermatic cord torsion: effects of cyclosporine and prednisone on fertility and the contralateral testis in the rat. (2254174)
1990
34
Spermatic cord torsion. (3813629)
1987
35
Spermatic cord torsion in the neonate. (3476079)
1987
36
Testicular salvage following spermatic cord torsion. (3559866)
1987
37
Histopathology of prepubertal rat testes subjected to various durations of spermatic cord torsion. (3944017)
1986
38
Spermatic cord torsion. (3717988)
1986
39
Histological changes occurring in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion. (3989935)
1985
40
Spermatic cord torsion: diagnostic limitations. (2999690)
1985
41
The effect of prepubertal spermatic cord torsion on subsequent fertility in rats. (6715258)
1984
42
Spermatic cord block and manual reduction: primary treatment for spermatic cord torsion. (6492282)
1984
43
Autoantibodies against Leydig cells in patients after spermatic cord torsion. (6362937)
1984
44
Spermatic cord torsion in the neonate. (6827663)
1983
45
Spermatic cord torsion and Sertoli cell tumor in a dog. (6138340)
1983
46
Histological study of the removed testes of patients after acute monolateral spermatic cord torsion. (6666858)
1983
47
Spermatic cord torsion following previous surgical fixation. (7143612)
1982
48
Immunological and clinical study of patients after spermatic cord torsion. (7039415)
1982
49
Spermatic cord torsion in a dog. (7207448)
1981
50
Bilateral spermatic cord torsion in the neonate. (7420615)
1980

Variations for Spermatic Cord Torsion

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Expression for genes affiliated with Spermatic Cord Torsion

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Search GEO for disease gene expression data for Spermatic Cord Torsion.

Pathways for genes affiliated with Spermatic Cord Torsion

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Pathways related to Spermatic Cord Torsion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5CASP3, NOS3
29.3C1R, CASP3

GO Terms for genes affiliated with Spermatic Cord Torsion

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Biological processes related to Spermatic Cord Torsion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell differentiationGO:00301548.8BMP1, CATSPER1, RFX2, TWIST1

Sources for Spermatic Cord Torsion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet