MCID: SPR016
MIFTS: 35

Spermatic Cord Torsion malady

Reproductive diseases category

Summaries for Spermatic Cord Torsion

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66Wikipedia, 48OMIM, 34MalaCards
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Wikipedia:66 Testicular torsion occurs when the spermatic cord (from which the testicle is suspended) twists, cutting... more...

MalaCards: Spermatic Cord Torsion, also known as torsion of testis unspecified, is related to ischemia and epididymitis. An important gene associated with Spermatic Cord Torsion is CHKB (choline kinase beta). The compounds gssg and selenium have been mentioned in the context of this disorder. Affiliated tissues include testis and testes.

Description from OMIM:48 187400

Aliases & Classifications for Spermatic Cord Torsion

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9Disease Ontology, 11DISEASES, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH, 28ICD9CM, 48OMIM, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Aliases & Descriptions:

spermatic cord torsion 9 11 63
torsion of testis unspecified 9
torsion of spermatic cord 9
torsion of testis nos 9
torsion of testicle 9
testicular torsion 9
torsion of testis 9
torsion 63


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Disease Ontology9 DOID:11996
NCIt41 C26885
MeSH36 D013086
ICD9CM28 608.20, 608.2
OMIM48 187400
ICD1026 N44

Related Diseases for Spermatic Cord Torsion

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Spermatic Cord Torsion:



Diseases related to spermatic cord torsion

Symptoms for Spermatic Cord Torsion

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48OMIM
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Clinical features from OMIM:

187400

Drugs & Therapeutics for Spermatic Cord Torsion

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Spermatic Cord Torsion

Genetic Tests for Spermatic Cord Torsion

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Anatomical Context for Spermatic Cord Torsion

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34MalaCards
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MalaCards organs/tissues related to Spermatic Cord Torsion:

34
Testis, Testes

Animal Models for Spermatic Cord Torsion or affiliated genes

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Publications for Spermatic Cord Torsion

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53PubMed
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Articles related to Spermatic Cord Torsion:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Missed spermatic cord torsion in an old man. (24175049)
2013
2
Sertoli cell tumors associated with feminizing syndrome and spermatic cord torsion in two cryptorchid dogs. (22705745)
2012
3
Subsequent alterations in the contractile property ofA the vas deferens according to duration of spermatic cord torsion. (21890132)
2011
4
Spermatic cord knot: a clinical finding in patients with spermatic cord torsion. (22190915)
2011
5
The morphological evaluation of ipsilateral and contralateral vasa deferentia in a rat model of unilateral spermatic cord torsion. (19921213)
2010
6
Experimental unilateral spermatic cord torsion: the effect of polypolymerase enzyme inhibitor on histopathological and biochemical changes in the early and late periods in the ipsilateral and contralateral testicles. (20579694)
2010
7
Spermatic cord torsion with preserved testis perfusion: initial anatomical observations. (15538271)
2004
8
Unilateral spermatic cord torsion without ipsilateral spermatogenetic material: effects on testicular blood flow and fertility potential. (14579109)
2004
9
Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury. (15051328)
2004
10
Sonographic diagnosis of acute spermatic cord torsion. Rotation of the cord: a key to the diagnosis. (12107581)
2002
11
The effect of methylene blue on histological damage after spermatic cord torsion in a rat model. (11446854)
2001
12
Spermatic cord torsion after testicular fixation. A different surgical approach and a revision of current techniques. (11807671)
2001
13
Noradrenaline and nitrite-nitrate concentrations in the contralateral testes during ipsilateral spermatic cord torsion in the presence or absence of a testis and epididymis. (10368208)
1999
14
DNA flow cytometry reveals depressed spermatogenetic activity in the contralateral testis within 24 h of ipsilateral spermatic cord torsion independently of the presence of the testis and epididymis. (9748690)
1998
15
Influence of experimental spermatic cord torsion on the contralateral testis in rats. Evaluation of tissue free oxygen radical scavenger enzyme levels. (9253119)
1997
16
Serum creatine kinase enzyme levels in the early diagnosis of spermatic cord torsion. (9008324)
1996
17
Acute spermatic cord torsion alters the microcirculation of the contralateral testis. (7490885)
1996
18
Is ipsilateral testis mandatory for the occurrence of contralateral intratesticular biochemical changes indicative of hypoxia after unilateral spermatic cord torsion? (8529740)
1995
19
Is ipsilateral testis mandatory for contralateral testicular deterioration encountered following spermatic cord torsion? (7974914)
1994
20
Spermatic cord torsion in adults. (7817170)
1994
21
Variability of ischemia during spermatic cord torsion in the rat. (8126796)
1994
22
Spermatic cord torsion in an infant receiving human chorionic gonadotropin. (8103805)
1993
23
Spermatic cord torsion: loss of spermatogenesis despite return of blood flow. (8373967)
1993
24
The alterations of cellular metabolism in the contralateral testis following spermatic cord torsion in rats. (8326602)
1993
25
The effect of polyethylene glycol-superoxide dismutase administration on histological damage following spermatic cord torsion. (1640536)
1992
26
Sonographic appearance of the torsion knot in spermatic cord torsion. (1414769)
1992
27
Color Doppler ultrasound compared to a radionuclide scanning of spermatic cord torsion in a canine model. (1846434)
1991
28
The effect of various degrees of unilateral spermatic cord torsion on fertility in the rat. (2374208)
1990
29
Spermatic cord torsion: effects of cyclosporine and prednisone on fertility and the contralateral testis in the rat. (2254174)
1990
30
Intrauterine spermatic cord torsion in the newborn: sonographic and pathologic correlation. (2243983)
1990
31
Spermatic cord torsion. Contralateral testicular degeneration at various ages in the rat. (2086577)
1990
32
Spermatic cord torsion. (3813629)
1987
33
Testicular salvage following spermatic cord torsion. (3559866)
1987
34
Spermatic cord torsion in the neonate. (3476079)
1987
35
Histopathology of prepubertal rat testes subjected to various durations of spermatic cord torsion. (3944017)
1986
36
Spermatic cord torsion. (3717988)
1986
37
Histological changes occurring in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion. (3989935)
1985
38
Spermatic cord torsion: diagnostic limitations. (2999690)
1985
39
Autoantibodies against Leydig cells in patients after spermatic cord torsion. (6362937)
1984
40
The effect of prepubertal spermatic cord torsion on subsequent fertility in rats. (6715258)
1984
41
Spermatic cord torsion in the neonate. (6827663)
1983
42
Histological study of the removed testes of patients after acute monolateral spermatic cord torsion. (6666858)
1983
43
Spermatic cord torsion and Sertoli cell tumor in a dog. (6138340)
1983
44
Spermatic cord torsion following previous surgical fixation. (7143612)
1982
45
Immunological and clinical study of patients after spermatic cord torsion. (7039415)
1982
46
Spermatic cord torsion in a dog. (7207448)
1981
47
Bilateral spermatic cord torsion in the neonate. (7354546)
1980
48
Bilaterally enlarged testicles in a newborn: an atypical presentation of intrauterine spermatic cord torsion. (7191631)
1980
49
Bilateral spermatic cord torsion in the neonate. (7420615)
1980
50
Spermatic cord torsion in the newborn. (1273783)
1976

Variations for Spermatic Cord Torsion

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Expression for genes affiliated with Spermatic Cord Torsion

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Spermatic Cord Torsion

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Pathways for genes affiliated with Spermatic Cord Torsion

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Compounds for genes affiliated with Spermatic Cord Torsion

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46Novoseek, 25HMDB, 12DrugBank
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Compounds related to Spermatic Cord Torsion according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1gssg469.4CAT, CHKB
2selenium46 2510.4CAT, CHKB
3malondialdehyde469.4CAT, CHKB
4peroxynitrite469.4CAT, CHKB
5uric acid46 2510.4CHKB, CAT
6levodopa46 1210.4CAT, CHKB
7glucose 6-phosphate46 2510.4CAT, CHKB
8alpha tocopherol469.4CAT, CHKB
9mannitol46 1210.3CHKB, CAT
10citrate469.3CAT, CHKB
11agar469.3CAT, CHKB
12n acetylcysteine469.2CAT, CHKB
13ascorbic acid46 2510.2CHKB, CAT
14lactate469.1CAT, CHKB
15nitric oxide46 25 1211.1CAT, CHKB
16superoxide46 2510.0CAT, CHKB
17h2o2468.8CAT, CHKB

GO Terms for genes affiliated with Spermatic Cord Torsion

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Products for genes affiliated with Spermatic Cord Torsion

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Sources for Spermatic Cord Torsion

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet