MCID: SPR089
MIFTS: 14

Spermatogenic Failure 4 malady

Genetic diseases (common), Reproductive diseases categories

Aliases & Classifications for Spermatogenic Failure 4

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Aliases & Descriptions for Spermatogenic Failure 4:

Name: Spermatogenic Failure 4 46 9
Azoospermia Due to Perturbations of Meiosis 20
 
Arrest of Spermatogenesis 61


Classifications:



External Ids:

OMIM46 270960

Summaries for Spermatogenic Failure 4

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OMIM:46 Azoospermia, a condition in which there are no sperm present in the ejaculate, has historically been divided into 2... (270960) more...

MalaCards based summary: Spermatogenic Failure 4, is also known as azoospermia due to perturbations of meiosis, and has symptoms including autosomal dominant inheritance, autosomal recessive inheritance and azoospermia. An important gene associated with Spermatogenic Failure 4 is SYCP3 (synaptonemal complex protein 3).

Related Diseases for Spermatogenic Failure 4

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Symptoms for Spermatogenic Failure 4

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Symptoms by clinical synopsis from OMIM:

270960

Clinical features from OMIM:

270960

HPO human phenotypes related to Spermatogenic Failure 4:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 autosomal recessive inheritance HP:0000007
3 azoospermia HP:0000027
4 abnormality of metabolism/homeostasis HP:0001939
5 recurrent spontaneous abortion HP:0200067

Drugs & Therapeutics for Spermatogenic Failure 4

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Drug clinical trials:

Search ClinicalTrials for Spermatogenic Failure 4

Search NIH Clinical Center for Spermatogenic Failure 4

Genetic Tests for Spermatogenic Failure 4

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Genetic tests related to Spermatogenic Failure 4:

id Genetic test Affiliating Genes
1 Azoospermia Due to Perturbations of Meiosis20 SYCP3

Anatomical Context for Spermatogenic Failure 4

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Animal Models for Spermatogenic Failure 4 or affiliated genes

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Publications for Spermatogenic Failure 4

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Variations for Spermatogenic Failure 4

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Clinvar genetic disease variations for Spermatogenic Failure 4:

5
id Gene Variation Type Significance SNP ID Assembly Location
1SYCP3SYCP3, 1-BP DEL, 643AdeletionPathogenic
2SYCP3NM_153694.4(SYCP3): c.553-21_553-18delACTTdeletionrisk factorGRCh37Chr 12, 102123009: 102123012
3SYCP3SYCP3, 657T-Csingle nucleotide variantrisk factor

Expression for genes affiliated with Spermatogenic Failure 4

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Search GEO for disease gene expression data for Spermatogenic Failure 4.

Pathways for genes affiliated with Spermatogenic Failure 4

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Compounds for genes affiliated with Spermatogenic Failure 4

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GO Terms for genes affiliated with Spermatogenic Failure 4

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Sources for Spermatogenic Failure 4

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet