MCID: SPH007
MIFTS: 33

Sphenoid Sinusitis malady

Summaries for Sphenoid Sinusitis

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8Disease Ontology, 33MalaCards
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Disease Ontology:8 A sinusitis which involves infection of sphenoid sinuses that causes pain or pressure behind the eyes, but often refers to the vertex of the head.

MalaCards: Sphenoid Sinusitis, also known as sphenoidal sinusitis, is related to sinusitis and chronic sphenoidal sinusitis. An important gene associated with Sphenoid Sinusitis is PGRMC1 (progesterone receptor membrane component 1). The compounds lanreotide and leuprolide acetate have been mentioned in the context of this disorder. Affiliated tissues include pituitary.

Aliases & Classifications for Sphenoid Sinusitis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 35MeSH, 57SNOMED-CT, 40NCIt
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Aliases & Descriptions:

sphenoid sinusitis 8 10 61
sphenoidal sinusitis 8


External Ids:

Disease Ontology8 DOID:10794
MeSH35 D015524
SNOMED-CT57 13266007
NCIt40 C35031

Related Diseases for Sphenoid Sinusitis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Sphenoid Sinusitis:



Diseases related to sphenoid sinusitis

Clinical Features for Sphenoid Sinusitis

Drugs & Therapeutics for Sphenoid Sinusitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Sphenoid Sinusitis

Drug clinical trials:

Search ClinicalTrials for Sphenoid Sinusitis

Search NIH Clinical Center for Sphenoid Sinusitis

Search CenterWatch for Sphenoid Sinusitis

Genetic Tests for Sphenoid Sinusitis

Anatomical Context for Sphenoid Sinusitis

Sources:
33MalaCards
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MalaCards organs/tissues related to Sphenoid Sinusitis:

33
Pituitary

Animal Models for Sphenoid Sinusitis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Sphenoid Sinusitis

Sources:
51PubMed
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Articles related to Sphenoid Sinusitis:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Isolated Sinusitis of Lateral Recesses of Sphenoid Sinus. (24057972)
2013
2
Cavernous sinus thrombosis caused by contralateral sphenoid sinusitis: a case report. (23497466)
2013
3
Miller Fisher variant of Guillain-BarrAc syndrome masquerading as acute sphenoid sinusitis with orbital apex syndrome. (22447677)
2012
4
Bilateral sphenoid fungal sinusitis. (21792789)
2011
5
Cavernous sinus thrombosis secondary to contralateral sphenoid sinusitis: a diagnostic challenge. (20202275)
2010
6
Isolated sphenoid sinusitis presenting as blindness. (20155691)
2010
7
Lethal sphenoid fungal sinusitis in an immunocompromised elderly patient. (19902855)
2009
8
Headache induced by isolated sphenoid fungal sinusitis: sinus headache? (19763769)
2009
9
Pneumocephalus: a rare presentation of Candida sphenoid sinusitis. (19380081)
2009
10
Infectious aneurysm of the intracavernous carotid artery occurring concomitantly with sphenoid sinusitis; an autopsy case report. (19103450)
2009
11
Chronic sphenoid sinusitis revisited: comparison of multidetector axial sections, multiplanar reconstructions, and virtual sinoscopy with endoscopic sinus surgery. (17638786)
2007
12
Intracranial epidural abscess secondary to isolated sphenoid sinusitis. (18071992)
2007
13
An unusual presentation of sphenoid sinusitis with septicaemia in a healthy young adult. (16714490)
2006
14
Meningitis following relapsing painful ophthalmoplegia in aspergillus sphenoidal sinusitis: a case report. (16998735)
2006
15
Acute isolated sphenoid sinusitis in children. (16930730)
2006
16
A case of multiple cranial nerve palsy due to sphenoid sinusitis complicated by cerebral aneurysm. (16139977)
2005
17
Septic right superior ophthalmic vein thrombosis complicated by left sphenoid sinusitis. (15804672)
2005
18
Abducens palsy in acute isolated sphenoid fungal sinusitis. (15931819)
2004
19
Fulminant bacterial meningitis complicating sphenoid sinusitis. (14676492)
2003
20
The intracranial complication of acute isolated sphenoid sinusitis. (11772494)
2002
21
Epidural hematoma as a complication of sphenoid sinusitis and epidural abscess: a case report and literature review. (12427432)
2002
22
Bacteriology of acute and chronic sphenoid sinusitis. (12450174)
2002
23
Sphenoid sinusitis caused by Clostridium perfringens. (11458224)
2001
24
Rathke's cleft cyst presenting as sphenoid sinusitis. (11226953)
2001
25
Basilar artery vasculitis secondary to sphenoid sinusitis--case report. (11593974)
2001
26
Cavernous sinus thrombophlebitis caused by sphenoid sinusitis--report of autopsy case. (11430492)
2001
27
Diagnostic challenge. Not tonight, Dear. Answer: antibiotics for sphenoid sinusitis. (17610801)
2001
28
Sphenoid marsupialization for chronic sphenoidal sinusitis. (10942139)
2000
29
Isolated cryptococcal sphenoid sinusitis with septicemia, meningitis, and subsequent skull base osteomyelitis in an immunocompetent patient. (10964305)
2000
30
Pituitary abscess secondary to isolated sphenoid sinusitis. (10667827)
1999
31
Superior orbital fissure syndrome caused by indolent Aspergillus sphenoid sinusitis. (9450837)
1998
32
Isolated sphenoid sinusitis. (9403945)
1997
33
Endoscopic treatment of sphenoid sinusitis. (8643296)
1996
34
Intracranial extension of sphenoid sinusitis. (7672977)
1995
35
MR features of pachymeningitis presenting with sixth-nerve palsy secondary to sphenoid sinusitis. (7611085)
1995
36
Isolated sphenoid sinusitis. (8489666)
1993
37
Isolated palsy of the superior branch of the oculomotor nerve due to chronic erosive sphenoid sinusitis. (8113433)
1993
38
"Inverted sella turcica" appearance on skull X-ray due to chronic sphenoidal sinusitis. A report of two cases. (8237165)
1993
39
Isolated sphenoid sinusitis due to Pseudallescheria boydii. (8320525)
1993
40
Sphenoid sinusitis. (1994073)
1991
41
Acute isolated sphenoid sinusitis: a disease with complications. (1787363)
1991
42
Acute sphenoid sinusitis: management strategies. (3398104)
1988
43
Sphenoid sinusitis: the importance of CT scanning. (3381717)
1988
44
Pituitary abscess following asymptomatic sphenoid sinusitis. (6491509)
1984
45
Cavernous sinus thrombophlebitis secondary to sphenoid sinusitis. (6855403)
1983
46
Sphenoid sinusitis. A review of 30 cases. (6621661)
1983
47
Mucormycotic sphenoid sinusitis. (7318712)
1981
48
Acute sphenoid sinusitis causing spasm of the internal carotid artery. (4831938)
1974
49
ACUTE suppurative sphenoid sinusitis in child, simulating an acute encephalitis. (13060352)
1953
50
The conservative and surgical management of ethmoid and sphenoid sinusitis. (18106568)
1949

Genetic Variations for Sphenoid Sinusitis

Expression for genes affiliated with Sphenoid Sinusitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Sphenoid Sinusitis

Search GEO for disease gene expression data for Sphenoid Sinusitis.

Pathways for genes affiliated with Sphenoid Sinusitis

Compounds for genes affiliated with Sphenoid Sinusitis

Sources:
45Novoseek, 29IUPHAR, 24HMDB, 50PharmGKB, 11DrugBank, 60Tocris Bioscience
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Compounds related to Sphenoid Sinusitis according to GeneCards/GeneDecks:

(show all 33)
idCompoundScoreTop Affiliating Genes
1lanreotide45 2911.0KLK3, GH1
2leuprolide acetate459.9KLK3, GH1
3cortisone45 2410.9GH1, KLK3
4alendronate45 50 1111.8GH1, KLK3
5progestins459.7KLK3, GH1, PGRMC1
6provenge459.6ACPP, KLK3
7chlormadinone acetate459.6KLK3, ACPP
8estracyt459.6KLK3, ACPP
9estramustine phosphate459.6KLK3, ACPP
10nilutamide45 60 29 1112.6KLK3, ACPP
11goserelin45 29 1111.6KLK3, ACPP
12buserelin45 29 1111.6KLK3, ACPP
13propranolol45 29 50 11 2413.5NT5C2, GH1
14estramustine45 1110.5KLK3, ACPP
15finasteride45 60 11 2412.5ACPP, KLK3
16dtpa459.5ACPP, KLK3
17cyproteroneacetate459.5ACPP, KLK3
18flutamide45 60 1111.5KLK3, ACPP
19bicalutamide45 60 1111.4ACPP, KLK3
20diethylstilbestrol45 29 1111.3ACPP, KLK3
21deoxyribonucleic acid459.2KLK3, ACPP
22dehydroepiandrosterone sulfate459.2ACPP, GH1, KLK3
23dhea459.2ACPP, GH1, KLK3
24dihydrotestosterone45 29 11 2412.2ACPP, GH1, KLK3
25gnrh459.1KLK3, GH1, ACPP
26vitamin d459.0KLK3, GH1, ACPP
27estradiol45 11 2410.9KLK3, GH1, ACPP
28paraffin458.9ACPP, GH1, KLK3
29testosterone45 60 11 2411.8KLK3, GH1, PGRMC1, ACPP
30steroid458.8KLK3, GH1, PGRMC1, ACPP
31lactate458.7ACPP, GH1, KLK3
32estrogen458.6KLK3, GH1, PGRMC1, ACPP
33thymidine45 249.4ACPP, NT5C2, GH1

GO Terms for genes affiliated with Sphenoid Sinusitis

Sources:
16Gene Ontology
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Cellular components related to Sphenoid Sinusitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi cisternaGO:0319859.1GOLPH3, ACPP

Biological processes related to Sphenoid Sinusitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1purine nucleobase metabolic processGO:0061449.1ACPP, NT5C2

Products for genes affiliated with Sphenoid Sinusitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sphenoid Sinusitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet