MCID: SPH007
MIFTS: 35

Sphenoid Sinusitis malady

Summaries for Sphenoid Sinusitis

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A sinusitis which involves infection of sphenoid sinuses that causes pain or pressure behind the eyes, but often refers to the vertex of the head.

MalaCards: Sphenoid Sinusitis, also known as sphenoidal sinusitis, is related to acute sphenoidal sinusitis and chronic sphenoidal sinusitis. An important gene associated with Sphenoid Sinusitis is PGRMC1 (progesterone receptor membrane component 1). The compounds leuprolide acetate and lanreotide have been mentioned in the context of this disorder. Affiliated tissues include eye and pituitary.

Aliases & Classifications for Sphenoid Sinusitis

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8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

sphenoid sinusitis 8 10 60
sphenoidal sinusitis 8


External Ids:

Disease Ontology8 DOID:10794
MeSH34 D015524
SNOMED-CT56 13266007
NCIt39 C35031

Related Diseases for Sphenoid Sinusitis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Sphenoid Sinusitis:



Diseases related to sphenoid sinusitis

Clinical Features for Sphenoid Sinusitis

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Drugs & Therapeutics for Sphenoid Sinusitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Sphenoid Sinusitis

Drug clinical trials:

Search ClinicalTrials for Sphenoid Sinusitis

Search NIH Clinical Center for Sphenoid Sinusitis

Search CenterWatch for Sphenoid Sinusitis

Genetic Tests for Sphenoid Sinusitis

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Anatomical Context for Sphenoid Sinusitis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Sphenoid Sinusitis:

32
Eye, Pituitary

Animal Models for Sphenoid Sinusitis or affiliated genes

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Publications for Sphenoid Sinusitis

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50PubMed
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Articles related to Sphenoid Sinusitis:

(show top 50)    (show all 100)
idTitleAuthorsYear
1
Isolated Sinusitis of Lateral Recesses of Sphenoid Sinus. (24057972)
2013
2
Lessons from everyday practice: septic cavernous sinus thrombosis due to sphenoid sinusitis in a young patient following a road traffic accident. (23315463)
2013
3
Mini-nasoseptal flap for recalcitrant sphenoid sinusitis. (23562205)
2013
4
Cavernous sinus thrombosis caused by contralateral sphenoid sinusitis: a case report. (23497466)
2013
5
Acute sphenoid sinusitis induced blindness: a case report. (22070879)
2012
6
Pathology quiz case 1. Primary sinonasal inverted papilloma (SIP) of the ethmoid and sphenoid sinuses, with intracranial extension. (22710518)
2012
7
Bilateral sphenoid fungal sinusitis. (21792789)
2011
8
Cavernous sinus thrombosis secondary to contralateral sphenoid sinusitis: a diagnostic challenge. (20202275)
2010
9
Isolated sphenoid sinusitis presenting as blindness. (20155691)
2010
10
Endoscopic view of purulent sphenoid sinusitis. (19224473)
2009
11
Pneumocephalus: a rare presentation of Candida sphenoid sinusitis. (19380081)
2009
12
Infectious aneurysm of the intracavernous carotid artery occurring concomitantly with sphenoid sinusitis; an autopsy case report. (19103450)
2009
13
Chronic sphenoid sinusitis revisited: comparison of multidetector axial sections, multiplanar reconstructions, and virtual sinoscopy with endoscopic sinus surgery. (17638786)
2007
14
Intracranial epidural abscess secondary to isolated sphenoid sinusitis. (18071992)
2007
15
The clinical behavior of isolated sphenoid sinusitis. (17418260)
2007
16
Acute isolated sphenoid sinusitis in children. (16930730)
2006
17
Sphenoid sinusitis disguised by precocious puberty. (15656965)
2005
18
Abducens palsy in acute isolated sphenoid fungal sinusitis. (15931819)
2004
19
Acute isolated sphenoid sinusitis. (15531965)
2004
20
Isolated sphenoid sinusitis presenting with unilateral VIth nerve palsy. (15013621)
2004
21
Fulminant bacterial meningitis complicating sphenoid sinusitis. (14676492)
2003
22
The intracranial complication of acute isolated sphenoid sinusitis. (11772494)
2002
23
Epidural hematoma as a complication of sphenoid sinusitis and epidural abscess: a case report and literature review. (12427432)
2002
24
Bacteriology of acute and chronic sphenoid sinusitis. (12450174)
2002
25
Cemento-ossifying fibroma of maxillary and sphenoid sinuses: case report and literature review. (12212586)
2002
26
Sphenoid sinusitis caused by Clostridium perfringens. (11458224)
2001
27
Rathke's cleft cyst presenting as sphenoid sinusitis. (11226953)
2001
28
Basilar artery vasculitis secondary to sphenoid sinusitis--case report. (11593974)
2001
29
Cavernous sinus thrombophlebitis caused by sphenoid sinusitis--report of autopsy case. (11430492)
2001
30
Diagnostic challenge. Not tonight, Dear. Answer: antibiotics for sphenoid sinusitis. (17610801)
2001
31
Isolated cryptococcal sphenoid sinusitis with septicemia, meningitis, and subsequent skull base osteomyelitis in an immunocompetent patient. (10964305)
2000
32
Superior orbital fissure syndrome caused by indolent Aspergillus sphenoid sinusitis. (9450837)
1998
33
Isolated sphenoid sinusitis. (9403945)
1997
34
Obliteration of maxillary and sphenoid sinuses in Gaucher's disease. (9227238)
1997
35
Endoscopic treatment of sphenoid sinusitis. (8643296)
1996
36
Intracranial extension of sphenoid sinusitis. (7672977)
1995
37
MR features of pachymeningitis presenting with sixth-nerve palsy secondary to sphenoid sinusitis. (7611085)
1995
38
Isolated sphenoid sinusitis: the Toronto Hospital for Sick Children experience and review of the literature. (8170018)
1994
39
Isolated sphenoid sinusitis due to Pseudallescheria boydii. (8320525)
1993
40
Acute isolated sphenoid sinusitis: a disease with complications. (1787363)
1991
41
Acute sphenoid sinusitis: management strategies. (3398104)
1988
42
Sphenoid sinusitis: the importance of CT scanning. (3381717)
1988
43
Pituitary abscess following asymptomatic sphenoid sinusitis. (6491509)
1984
44
Cavernous sinus thrombophlebitis secondary to sphenoid sinusitis. (6855403)
1983
45
Sphenoid sinusitis. A review of 30 cases. (6621661)
1983
46
Acute sphenoid sinusitis presenting as aseptic meningitis: a pachymeningitis syndrome. (7095996)
1982
47
Mucormycotic sphenoid sinusitis. (7318712)
1981
48
ACUTE suppurative sphenoid sinusitis in child, simulating an acute encephalitis. (13060352)
1953
49
The conservative and surgical management of ethmoid and sphenoid sinusitis. (18106568)
1949
50
Optic Tract Lesion, Probably the Result of Opticochiasmal Arachnoiditis Due to Infected Sphenoid Sinuses. (16693143)
1938

Genetic Variations for Sphenoid Sinusitis

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Expression for genes affiliated with Sphenoid Sinusitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Sphenoid Sinusitis

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Pathways for genes affiliated with Sphenoid Sinusitis

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Compounds for genes affiliated with Sphenoid Sinusitis

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Sources:
44Novoseek, 28IUPHAR, 24HMDB, 49PharmGKB, 11DrugBank, 59Tocris Bioscience
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Compounds related to Sphenoid Sinusitis according to GeneCards/GeneDecks:

(show all 33)
idCompoundScoreTop Affiliating Genes
1leuprolide acetate4410.0KLK3, GH1
2lanreotide44 2810.9KLK3, GH1
3cortisone44 2410.9KLK3, GH1
4alendronate44 49 1111.8GH1, KLK3
5progestins449.7GH1, KLK3, PGRMC1
6provenge449.6KLK3, ACPP
7estracyt449.6KLK3, ACPP
8chlormadinone acetate449.6ACPP, KLK3
9estramustine phosphate449.6KLK3, ACPP
10goserelin44 28 1111.6KLK3, ACPP
11nilutamide44 59 28 1112.6KLK3, ACPP
12buserelin44 28 1111.5KLK3, ACPP
13estramustine44 1110.5ACPP, KLK3
14finasteride44 59 11 2412.5KLK3, ACPP
15dtpa449.5ACPP, KLK3
16cyproteroneacetate449.5KLK3, ACPP
17flutamide44 59 1111.5KLK3, ACPP
18bicalutamide44 59 1111.4KLK3, ACPP
19diethylstilbestrol44 28 1111.3ACPP, KLK3
20propranolol44 28 49 11 2413.2NT5C2, GH1
21deoxyribonucleic acid449.2KLK3, ACPP
22dehydroepiandrosterone sulfate449.2GH1, KLK3, ACPP
23dhea449.2ACPP, KLK3, GH1
24dihydrotestosterone44 28 11 2412.2GH1, KLK3, ACPP
25gnrh449.1ACPP, GH1, KLK3
26vitamin d449.0KLK3, GH1, ACPP
27estradiol44 11 2410.9KLK3, ACPP, GH1
28paraffin448.9KLK3, GH1, ACPP
29testosterone44 59 11 2411.8KLK3, GH1, ACPP, PGRMC1
30steroid448.8PGRMC1, GH1, KLK3, ACPP
31thymidine44 249.7GH1, NT5C2, ACPP
32lactate448.7KLK3, ACPP, GH1
33estrogen448.6PGRMC1, ACPP, GH1, KLK3

GO Terms for genes affiliated with Sphenoid Sinusitis

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16Gene Ontology
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Cellular components related to Sphenoid Sinusitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi cisternaGO:0319859.1GOLPH3, ACPP

Biological processes related to Sphenoid Sinusitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1purine nucleobase metabolic processGO:0061449.1ACPP, NT5C2

Products for genes affiliated with Sphenoid Sinusitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sphenoid Sinusitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet