KD
MCID: SPN066
MIFTS: 27

Spinal-Bulbar Muscular Atrophy (KD) malady

Genetic diseases (common), Immune diseases, Muscle diseases categories

Summaries for Spinal-Bulbar Muscular Atrophy

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22Genetics Home Reference, 66Wikipedia, 20GeneReviews, 34MalaCards
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Genetics Home Reference:22 Spinal and bulbar muscular atrophy, also known as Kennedy disease, is a disorder of specialized nerve cells that control muscle movement (motor neurons). These nerve cells originate in the spinal cord and the part of the brain that is connected to the spinal cord (the brainstem).

MalaCards: Spinal-Bulbar Muscular Atrophy, also known as spinal and bulbar muscular atrophy, is related to muscular atrophy and x-linked spinal-bulbar muscle atrophy. An important gene associated with Spinal-Bulbar Muscular Atrophy is AR (androgen receptor). Affiliated tissues include lymph node, heart and skeletal muscle.

Wikipedia:66 Muscle atrophy is defined as a decrease in the mass of the muscle; it can be a partial or complete... more...

GeneReviews summary for kennedy

Aliases & Classifications for Spinal-Bulbar Muscular Atrophy

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66Wikipedia, 20GeneReviews, 21GeneTests, 22Genetics Home Reference, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Immune diseases, Muscle diseases


Aliases & Descriptions:

spinal-bulbar muscular atrophy 66
spinal and bulbar muscular atrophy 20 21 22
kennedy's disease 20 22
sbma 20 22
spinal and bulbar muscular atrophy, x-linked 1 63
x-linked spinal and bulbar muscular atrophy 22
kennedy spinal and bulbar muscular atrophy 22
x-linked spinalbulbar muscular atrophy 20
bulbospinal muscular atrophy, x-linked 22
mucocutaneous lymph node syndrome 63
atrophy, muscular, spinobulbar 63
kennedy disease 22
kd 22


Related Diseases for Spinal-Bulbar Muscular Atrophy

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Spinal-Bulbar Muscular Atrophy:



Diseases related to spinal-bulbar muscular atrophy

Symptoms for Spinal-Bulbar Muscular Atrophy

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Drugs & Therapeutics for Spinal-Bulbar Muscular Atrophy

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Spinal-Bulbar Muscular Atrophy

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21GeneTests
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Genetic tests related to Spinal-Bulbar Muscular Atrophy:

id Genetic test Affiliating Genes
1 Spinal and Bulbar Muscular Atrophy21 AR

Anatomical Context for Spinal-Bulbar Muscular Atrophy

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34MalaCards
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MalaCards organs/tissues related to Spinal-Bulbar Muscular Atrophy:

34
Lymph node, Heart, Skeletal muscle

Animal Models for Spinal-Bulbar Muscular Atrophy or affiliated genes

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Publications for Spinal-Bulbar Muscular Atrophy

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53PubMed
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Articles related to Spinal-Bulbar Muscular Atrophy:

(show all 15)
idTitleAuthorsYear
1
Sequencing analysis of the spinal bulbar muscular atrophy CAG expansion reveals absence of repeat interruptions. (24041967)
2014
2
Androgen receptors in muscle fibers induce rapid loss of force but not mass: implications for spinal bulbar muscular atrophy. (23629944)
2013
3
FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. (23062703)
2013
4
Complications after cardiovascular surgery in a case of undiagnosed spinal-bulbar muscular atrophy (Kennedy disease). (22381992)
2012
5
Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy. (20689246)
2011
6
Microarray analysis of gene expression by skeletal muscle of three mouse models of Kennedy disease/spinal bulbar muscular atrophy. (20886071)
2010
7
Standard and modified statistical MUNE evaluations in spinal-bulbar muscular atrophy. (19670325)
2009
8
Recovery of function in a myogenic mouse model of spinal bulbar muscular atrophy. (19211034)
2009
9
Androgen receptor and Kennedy disease/spinal bulbar muscular atrophy. (18321505)
2008
10
Natural history of spinal-bulbar muscular atrophy. (18490617)
2008
11
Clinical manifestations and molecular genetics of spinal bulbar muscular atrophy: report of 5 cases]. (17803850)
2007
12
Neurologic course, endocrine dysfunction and triplet repeat size in spinal bulbar muscular atrophy. (15376484)
2004
13
Structural and functional alterations in the androgen receptor in spinal bulbar muscular atrophy. (11356158)
2001
14
Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors. (11335100)
2001
15
Sensory involvement in spinal-bulbar muscular atrophy (Kennedy's disease). (10639619)
2000

Variations for Spinal-Bulbar Muscular Atrophy

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Expression for genes affiliated with Spinal-Bulbar Muscular Atrophy

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Spinal-Bulbar Muscular Atrophy

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Pathways for genes affiliated with Spinal-Bulbar Muscular Atrophy

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Compounds for genes affiliated with Spinal-Bulbar Muscular Atrophy

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GO Terms for genes affiliated with Spinal-Bulbar Muscular Atrophy

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Products for genes affiliated with Spinal-Bulbar Muscular Atrophy

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  • Antibodies
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Sources for Spinal-Bulbar Muscular Atrophy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet