MCID: SPN042
MIFTS: 28

Spinal Cord Ependymoma malady

Neuronal diseases, Cancer diseases categories

Summaries for Spinal Cord Ependymoma

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32MalaCards
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MalaCards: Spinal Cord Ependymoma, also known as ependymal neoplasm of the spinal cord, is related to adult spinal cord ependymoma and neurofibromatosis. An important gene associated with Spinal Cord Ependymoma is NF2 (neurofibromin 2 (merlin)). Affiliated tissues include spinal cord, and related mouse phenotypes are hearing/vestibular/ear and endocrine/exocrine gland.

Aliases & Classifications for Spinal Cord Ependymoma

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 39NCIt, 56SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

spinal cord ependymoma 8 10 44
ependymal neoplasm of the spinal cord 8
ependymoma of spinal cord 60


External Ids:

Disease Ontology8 DOID:5503
SNOMED-CT56 254949006
NCIt39 C3875

Related Diseases for Spinal Cord Ependymoma

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17GeneCards, 18GeneDecks
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Diseases in the Spinal Cord Ependymoma family:

Adult Spinal Cord Ependymoma

Diseases related to Spinal Cord Ependymoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1adult spinal cord ependymoma10.5
2neurofibromatosis10.3
3syringomyelia10.2
4wermer syndrome10.2
5neurogenic bladder10.2
6myxopapillary ependymoma10.2
7cervicitis10.2
8hydrocephalus10.2
9malignant ependymoma10.2
10multiple sclerosis10.2
11paraplegia10.2
12colorectal cancer10.0NF2
13ependymoma10.0NF2
14ovarian cancer10.0NF2

Graphical network of diseases related to Spinal Cord Ependymoma:



Diseases related to spinal cord ependymoma

Clinical Features for Spinal Cord Ependymoma

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Drugs & Therapeutics for Spinal Cord Ependymoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Spinal Cord Ependymoma

Search CenterWatch for Spinal Cord Ependymoma

Genetic Tests for Spinal Cord Ependymoma

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Anatomical Context for Spinal Cord Ependymoma

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32MalaCards
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MalaCards organs/tissues related to Spinal Cord Ependymoma:

32
Spinal cord

Animal Models for Spinal Cord Ependymoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Spinal Cord Ependymoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.3EPHB3, NF2
2MP:00053798.6HOXB13, EPHB3, NF2
3MP:00053898.5HOXB13, EPHB3, NF2
4MP:00053868.4NF2, EPHB3, HOXB13
5MP:00036318.2HOXB13, EPHB3, NF2

Publications for Spinal Cord Ependymoma

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50PubMed
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Articles related to Spinal Cord Ependymoma:

(show top 50)    (show all 58)
idTitleAuthorsYear
1
Spinal cord ependymoma in children--results of postoperative radiotherapy. (23490267)
2013
2
Giant spinal cord ependymoma with CSF spread. (23008221)
2012
3
Multiple sclerosis coexisting with spinal cord ependymoma: a case report. (23126220)
2012
4
Cytologic diagnosis of spinal cord ependymoma in cerebrospinal fluid. (23547427)
2012
5
Giant cell ependymoma of a cervical spinal cord. (21393921)
2011
6
Surgical technique and outcomes in the treatment of spinal cord ependymomas: part II: myxopapillary ependymoma. (21099714)
2011
7
Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database. (20672934)
2010
8
Spinal cord tanycytic ependymoma associated with neurofibromatosis type 2. (20403699)
2010
9
Clinical analysis of 21 cases of spinal cord ependymoma : positive clinical results of gross total resection. (20224707)
2010
10
Tanycytic ependymoma of the spinal cord with anaplastic cytological features. (19408091)
2009
11
Total removal of cervicothoracic intramedullary 160-mm-long spinal cord ependymoma: a rare case report. (21686716)
2009
12
Giant cell ependymoma of the spinal cord and fourth ventricle coexisting with syringomyelia. (18825598)
2008
13
Unexpected myxopapillary ependymoma within a filum terminale tethering the spinal cord. (17627148)
2007
14
Outcome predictors in the management of spinal cord ependymoma. (16865377)
2007
15
Imaging features of clear-cell ependymoma of the spinal cord. (17279401)
2007
16
Intramedullary clear cell ependymoma in the thoracic spinal cord: a case with its crush smear and ultrastructural findings. (17923743)
2007
17
Subtle clinical signs of a spinal cord ependymoma at the cervicothoracic level in an adult: a case report. (17549184)
2006
18
Surgical and radiotherapy treatment of a spinal cord ependymoma in a dog. (16498832)
2006
19
Anaplastic ependymoma in the cervical spinal cord of a maltese dog. (15472485)
2004
20
Tanycytic ependymoma of the spinal cord. Case report and review of the literature. (14735006)
2003
21
Spinal cord ependymoma: radical surgical resection and outcome. (12879876)
2003
22
Clear cell ependymoma with a lipidized component that developed in the thoracic spinal cord. (12870256)
2003
23
Etoposide for recurrent spinal cord ependymoma. (11971113)
2002
24
Special feature: pathological case of the month. Diagnosis and discussion: neurofibromatosis 2 with bilateral vestibular schwannomas and spinal cord ependymoma. (10980805)
2000
25
Spinal cord ependymoma presenting with acute paraplegia due to tumoral bleeding. (11105838)
2000
26
Intramedullary clear cell ependymoma in the cervical spinal cord: case report. (11126915)
2000
27
Surgical outcome of intramedullary spinal cord ependymoma. (10352743)
1999
28
Diagnosis of spinal cord ependymoma and astrocytic tumours with magnetic resonance imaging. (10833579)
1999
29
Lipidized (foamy) tumor cells in a spinal cord ependymoma with collagenous metaplasia. (9560021)
1998
30
Frequent type 2 neurofibromatosis gene transcript mutations in sporadic intramedullary spinal cord ependymomas. (8805149)
1996
31
Giant spinal cord ependymoma in a child. Case report. (8913964)
1996
32
Spinal cord ependymoma: a positron emission tomographic study with (11C-methyl)-L-methionine. (8773278)
1996
33
Cervical dystonia due to spinal cord ependymoma: involvement of cervical cord segments in the pathogenesis of dystonia. (7565833)
1995
34
The pathogenesis of syringomyelia in spinal cord ependymoma. (7889696)
1994
35
Papilloedema and hydrocephalus in spinal cord ependymoma. (8199121)
1994
36
Intramedullary abscess associated with a spinal cord ependymoma: case report. (1738441)
1992
37
Postoperative radiotherapy in the management of spinal cord ependymoma. (2013772)
1991
38
Anaplastic ependymoma of the spinal cord in childhood. A case report. (2203230)
1990
39
Papillary ependymoma of the cervical spinal cord. (2927592)
1989
40
Spinal cord ependymoma in two young dogs. (3051647)
1988
41
A case of malignant spinal cord ependymoma in association with a duplication of part of the long arm of chromosome 12. (3989836)
1985
42
Thoracic spinal cord ependymoma presenting with ejaculatory failure. Case report. (7054411)
1982
43
Case report. Anaplastic ependymoma of the spinal cord. (7413015)
1980
44
Flaccid neurogenic bladder as a presenting symptom of spinal cord ependymoma. (513236)
1979
45
Spinal cord ependymoma in a dog. (245206)
1977
46
Rapid arteriovenous shunting in a spinal cord ependymoma. Case report. (1271096)
1976
47
A huge intramedullary spinal cord ependymoma with complete recovery following total excision. (1238917)
1975
48
Repeated "occult" spinal subarachnoid hemorrhage and spinal cord ependymoma. (4854114)
1974
49
Rupture of spinal cord ependymoma. Case report. (4743575)
1973
50
Giant ependymoma of the spinal cord associated with papilledema. Review of literature and report of a case. (13837416)
1960

Genetic Variations for Spinal Cord Ependymoma

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Expression for genes affiliated with Spinal Cord Ependymoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Spinal Cord Ependymoma

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Pathways for genes affiliated with Spinal Cord Ependymoma

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Compounds for genes affiliated with Spinal Cord Ependymoma

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GO Terms for genes affiliated with Spinal Cord Ependymoma

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16Gene Ontology
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Biological processes related to Spinal Cord Ependymoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1angiogenesisGO:0015259.1HOXB13, EPHB3

Products for genes affiliated with Spinal Cord Ependymoma

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Sources for Spinal Cord Ependymoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet