MCID: SPN196
MIFTS: 11

Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant malady

Muscle category

Summaries for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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MalaCards: Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant, also known as spinal muscular atrophy, is related to spinal muscular atrophy and muscular atrophy. An important gene associated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant is DYNC1H1 (dynein, cytoplasmic 1, heavy chain 1).

Aliases & Classifications for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Muscle


Aliases & Descriptions:

spinal muscular atrophy, lower extremity, autosomal dominant 20 61
spinal muscular atrophy 61


Related Diseases for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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17GeneCards, 18GeneDecks
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Diseases related to Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1spinal muscular atrophy11.6
2muscular atrophy11.6
3survival motor neuron spinal muscular atrophy11.0
4proximal spinal muscular atrophy11.0
5adult spinal muscular atrophy10.9
6spinal muscular atrophy with respiratory distress 110.9
7juvenile spinal muscular atrophy10.9
8werdnig-hoffman disease10.7
9spinal muscular atrophy 110.7
10werdnig-hoffmann disease10.7
11distal spinal muscular atrophy, type v10.7
12progressive muscular atrophy10.6
13spinal muscular atrophy type 210.6
14spinal muscular atrophy with progressive myoclonic epilepsy10.6
15lateral sclerosis10.6
16amyotrophic lateral sclerosis10.6
17distal congenital nonprogressive spinal muscular atrophy10.6
18spinal muscular atrophy, lower extremity-predominant, ad10.6
19duchenne muscular dystrophy10.5
20adult progressive spinal muscular atrophy aran duchenne type10.5
21spinal muscular atrophy, lower extremity-predominant, 2, ad10.5
22spinal muscular atrophy, x-linked 2, infantile10.5
23distal spinal muscular atrophy type 310.5
24intermediate spinal muscular atrophy10.5
25arthrogryposis spinal muscular atrophy10.5
26neuropathy, distal hereditary motor, jerash type10.5
27spinal muscular atrophy, late-onset, finkel type10.5
28spinocerebellar ataxia 3510.4
29becker muscular dystrophy10.4
30tooth disease10.4
31spinal muscular atrophy, x-linked infantile10.4
32amyotrophy, neurogenic scapuloperoneal, new england type10.4
33spinal muscular atrophy, distal, autosomal recessive, 410.4
34distal hereditary motor neuropathy type 110.4
35axonal neuropathy10.4
36olivopontocerebellar atrophy10.4
37limb-girdle muscular dystrophy10.4
38x-linked spinal-bulbar muscle atrophy10.4
39spinal-bulbar muscular atrophy10.4
40congenital benign spinal muscular atrophy dominant10.4
41monomelic amyotrophy10.4
42spinal muscular atrophy ryukyuan type10.4
43spinal muscular atrophy, proximal, adult, autosomal dominant10.4
44distal spinal muscular atrophy 410.4
45distal hereditary motor neuropathy type v10.4
46spinal muscular atrophy, distal, autosomal recessive, 510.4
47spinal muscular atrophy, distal, x-linked 310.4
48spinal muscular atrophy - dandy-walker complex - cataracts10.4
49cystic fibrosis10.3
50distal hereditary motor neuropathy10.3

Graphical network of the top 20 diseases related to Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant:



Diseases related to spinal muscular atrophy, lower extremity, autosomal dominant

Clinical Features for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Drugs & Therapeutics for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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Genetic tests related to Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant:

id Genetic test Affiliating Genes
1 Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant20 DYNC1H1

Anatomical Context for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Animal Models for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant or affiliated genes

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28inGenious Targeting Laboratory
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Publications for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Genetic Variations for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Expression for genes affiliated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Search GEO for disease gene expression data for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant.

Pathways for genes affiliated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Compounds for genes affiliated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

GO Terms for genes affiliated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

Products for genes affiliated with Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

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Sources for Spinal Muscular Atrophy, Lower Extremity, Autosomal Dominant

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet