Aliases & Classifications for Spinal Stenosis

Aliases & Descriptions for Spinal Stenosis:

Name: Spinal Stenosis 38 12 52 41 42 14
Spinal Stenosis of Lumbar Region 12 69
Spinal Stenosis in Cervical Region 69
Cervical Spinal Stenosis 12
Lumbar Spinal Stenosis 12

Classifications:



Summaries for Spinal Stenosis

MedlinePlus : 41 your spine, or backbone, protects your spinal cord and allows you to stand and bend. spinal stenosis causes narrowing in your spine. the narrowing puts pressure on your nerves and spinal cord and can cause pain. spinal stenosis occurs mostly in people older than 50. younger people with a spine injury or a narrow spinal canal are also at risk. diseases such as arthritis and scoliosis can cause spinal stenosis, too. symptoms might appear gradually or not at all. they include pain in your neck or back numbness, weakness, cramping, or pain in your arms or legs pain going down the leg foot problems doctors diagnose spinal stenosis with a physical exam and imaging tests. treatments include medications, physical therapy, braces, and surgery. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards based summary : Spinal Stenosis, also known as spinal stenosis of lumbar region, is related to albright's hereditary osteodystrophy and cauda equina syndrome, and has symptoms including neck pain, torticollis and back pain. An important gene associated with Spinal Stenosis is CALCA (Calcitonin Related Polypeptide Alpha), and among its related pathways/superpathways are ERK Signaling and Integrin Pathway. The drugs Teriparatide and Betamethasone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and testes, and related phenotypes are hearing/vestibular/ear and limbs/digits/tail

Disease Ontology : 12 A bone deterioration disease that has material basis in bony spurs, disc degeneration, or thickened ligaments which results_in narrowing located in spinal cord.

Wikipedia : 71 Spinal stenosis is an abnormal narrowing (stenosis) of the spinal canal that may occur in any of the... more...

Related Diseases for Spinal Stenosis

Diseases related to Spinal Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 100)
id Related Disease Score Top Affiliating Genes
1 albright's hereditary osteodystrophy 28.9 ACAN COL11A1
2 cauda equina syndrome 11.1
3 hypochondroplasia 11.1
4 foot drop 11.1
5 buschke-ollendorff syndrome 11.1
6 acrodysostosis 2, with or without hormone resistance 10.9
7 spinal disease 10.8
8 spinal cord disease 10.8
9 chromosome 20 trisomy 10.8
10 central nervous system adult germ cell tumor 10.2 MMP3 TIMP2
11 spondylolisthesis 10.2
12 chondrodysplasia punctata, rhizomelic, type 1 10.2 MMP3 TIMP1
13 cervicitis 10.2
14 striated muscle rhabdoid tumor 10.1 TIMP1 TIMP2
15 angiomyoma 10.1 MMP3 TIMP1 TIMP2
16 schwannomatosis 10.1 MMP3 TIMP1 TIMP2
17 maxillary neoplasm 10.1 TIMP1 TIMP2
18 retinal drusen 10.1 TIMP1 TIMP2
19 back pain 10.1
20 mixed ductal-endocrine carcinoma 10.1 MMP3 TIMP1 TIMP2
21 puerperal pulmonary embolism 10.1 MMP3 TIMP1 TIMP2
22 bone angioendothelial sarcoma 10.1 ACAN MMP3 TIMP1
23 systemic scleroderma 10.1 BMP7 MMP3
24 adenoid squamous cell carcinoma 10.1 TIMP1 TIMP2
25 mild hemophilia a 10.1 COL9A1 COL9A2 COL9A3
26 radiculopathy 10.0
27 myopia, x-linked 10.0 COL9A1 COL9A2 COL9A3
28 lipid-rich carcinoma 10.0 BMP7 CALCA TIMP1
29 warm antibody hemolytic anemia 10.0 COL11A1 COL9A2
30 cerebral beriberi 10.0 COL9A2 COL9A3 THBS2
31 dentin dysplasia 10.0 ACAN CALCA COL9A3 MMP3
32 intermittent claudication 10.0
33 epiphyseal dysplasia, multiple, with myopia and deafness 10.0 ACAN COL11A1
34 osteoarthritis 9.9
35 achondroplasia 9.9
36 deafness, autosomal dominant 13 9.9 COL11A1 COL11A2
37 immunodeficiency 30 9.9 ACAN COL9A1 COL9A2 COL9A3
38 scoliosis 9.9
39 intermediate uveitis 9.9 ACAN COL9A1 COL9A2 COL9A3
40 salt and pepper syndrome 9.9 COL11A1 COL11A2
41 osteonecrosis 9.9 ACAN COL9A1 MMP3 TIMP1
42 quadriplegia 9.8
43 hyperostosis 9.8
44 laryngomalacia 9.8 COL11A1 COL11A2 COL9A1
45 bone resorption disease 9.8 ACAN BMP7 COL9A2 COL9A3 MMP3
46 physical disorder 9.8 ACAN BMP7 COL9A2 COL9A3 MMP3
47 maternally-inherited mitochondrial dystonia 9.7 COL11A1 COL9A1 COL9A2 COL9A3
48 osteopetrosis 9.7 ACAN BMP7 COL9A1 COL9A2 COL9A3
49 renal osteodystrophy 9.7
50 artery disease 9.7

Comorbidity relations with Spinal Stenosis via Phenotypic Disease Network (PDN):


Acute Cystitis Hypertension, Essential
Spinal Cord Disease

Graphical network of the top 20 diseases related to Spinal Stenosis:



Diseases related to Spinal Stenosis

Symptoms & Phenotypes for Spinal Stenosis

UMLS symptoms related to Spinal Stenosis:


neck pain, torticollis, back pain, low back pain, sciatica

MGI Mouse Phenotypes related to Spinal Stenosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hearing/vestibular/ear MP:0005377 9.55 BMP7 COL11A1 COL11A2 COL9A1 COL9A2
2 limbs/digits/tail MP:0005371 9.43 COL11A1 COL9A1 COL9A2 THBS2 TIMP1 BMP7
3 skeleton MP:0005390 9.23 BMP7 COL11A1 COL11A2 COL9A1 COL9A2 MMP3

Drugs & Therapeutics for Spinal Stenosis

Drugs for Spinal Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 215)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Teriparatide Approved, Investigational Phase 4 52232-67-4 16133850
2
Betamethasone Approved, Vet_approved Phase 4,Early Phase 1 378-44-9 9782
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
4
Lidocaine Approved, Vet_approved Phase 4,Early Phase 1 137-58-6 3676
5
Methylprednisolone Approved, Vet_approved Phase 4,Early Phase 1 83-43-2 6741
6
Prednisolone Approved, Vet_approved Phase 4,Early Phase 1 50-24-8 5755
7
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
8
Alprostadil Approved, Investigational Phase 4 745-65-3 149351
9
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
10
Diphenhydramine Approved Phase 4 58-73-1, 147-24-0 3100
11
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
12
Promethazine Approved Phase 4 60-87-7 4927
13
Menthol Approved Phase 4 2216-51-5 16666
14
Nicardipine Approved Phase 4 55985-32-5 4474
15
Remifentanil Approved Phase 4 132875-61-7 60815
16
Tranexamic Acid Approved Phase 4 1197-18-8 5526
17
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4 52485-79-7 40400 644073
18
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
19
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
20
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
21
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3 59467-70-8 4192
22
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
23
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3 57-27-2 5288826
24
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
25
Acetaminophen Approved Phase 4 103-90-2 1983
26
Oxymorphone Approved, Investigational, Vet_approved Phase 4 76-41-5 5284604
27 Bone Density Conservation Agents Phase 4
28 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
29 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Early Phase 1
30 Analgesics Phase 4,Phase 2,Phase 3
31 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
32 Anesthetics, Local Phase 4,Early Phase 1
33 Anti-Arrhythmia Agents Phase 4
34 Anti-Asthmatic Agents Phase 4,Phase 2,Phase 3,Early Phase 1
35 Antiemetics Phase 4,Early Phase 1
36 Anti-Inflammatory Agents Phase 4,Early Phase 1
37 Antineoplastic Agents, Hormonal Phase 4,Early Phase 1
38 Autonomic Agents Phase 4,Phase 2,Phase 3,Early Phase 1
39 BB 1101 Phase 4
40 Betamethasone benzoate Phase 4,Early Phase 1
41 Betamethasone sodium phosphate Phase 4,Early Phase 1
42 Betamethasone Valerate Phase 4,Early Phase 1 2152-44-5
43 Betamethasone-17,21-dipropionate Phase 4,Early Phase 1
44 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Early Phase 1
45 Dexamethasone 21-phosphate Phase 4
46 Dexamethasone acetate Phase 4 1177-87-3
47 Diuretics, Potassium Sparing Phase 4
48 Gastrointestinal Agents Phase 4,Early Phase 1
49 glucocorticoids Phase 4,Early Phase 1
50 HIV Protease Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 227)
id Name Status NCT ID Phase
1 Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans? Unknown status NCT02090244 Phase 4
2 Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial) Completed NCT01238536 Phase 4
3 Long-Term Outcomes for Lumbar Spinal Stenosis Patients Treated With X STOP® Completed NCT00534092 Phase 4
4 A Study to Evaluate Efficacy of 『Opast Tablet』for Neurologic Claudication in Patients With Lumbar Spinal Stenosis Completed NCT01888536 Phase 4
5 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
6 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
7 Intermittent Neurogenic Claudication Treatment With APERIUS® Completed NCT00887744 Phase 4
8 Lumbar Stenosis Outcomes Research (LUSTOR) Completed NCT00638443 Phase 4
9 Neurogenic Intermittent Claudication Evaluation Study Completed NCT00905359 Phase 4
10 MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study Completed NCT01082159 Phase 4
11 MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study Completed NCT00956631 Phase 4
12 Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis Completed NCT00995371 Phase 4
13 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumentated Posterolateral Fusionin The IVANOS-study Completed NCT02895555 Phase 4
14 Effect of Nicardipine on Renal Function in Deliberate Hypotension Completed NCT02271191 Phase 4
15 Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery Completed NCT02063035 Phase 4
16 Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery Completed NCT02416804 Phase 4
17 Efficacy of Pregabalin in Patients With Radicular Pain Completed NCT00908375 Phase 4
18 Gabapentin Versus Transdermal Fentanyl Matrix for Chronic Neuropathic Pain Completed NCT01127100 Phase 4
19 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
20 The Effect Site Concentration of Remifentanil for Conscious Sedation During Awake Nasotracheal Fiberoptic Intubation Completed NCT01052324 Phase 4
21 Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion Completed NCT00808665 Phase 4
22 The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery Completed NCT01053039 Phase 4
23 Caudal Epidural Steroid Injections for Low Back Pain/Sciatic Lumbar Pain Completed NCT01407913 Phase 4
24 Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation Completed NCT00000410 Phase 4
25 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4
26 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
27 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
28 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
29 TAVI Protocol - Paravertebral Block Study Recruiting NCT01404975 Phase 4
30 Condition of Approval Study Terminated NCT00517751 Phase 4
31 Lumbar Stenosis Outcomes Research II Terminated NCT00652093 Phase 4
32 Study on the Treatment of Degenerative Lumbar Spine Stenosis With a Percutaneous Interspinous Implant Terminated NCT01057641 Phase 4
33 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
34 Phase IV Comparing Rods of Yield Strengths to Correct Adolescent Idiopathic Scoliosis. Terminated NCT00768313 Phase 4
35 Effects of X-STOP® Versus Laminectomy Study Withdrawn NCT00558129 Phase 4
36 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
37 Surgical Versus Nonsurgical Treatment for Spinal Stenosis Completed NCT00022776 Phase 3
38 Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy Completed NCT00939406 Phase 2, Phase 3
39 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
40 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
41 The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam Completed NCT01275547 Phase 2, Phase 3
42 Ephedrine and Phenylephrine for Spinal Hypotension Recruiting NCT03047109 Phase 2, Phase 3
43 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis Active, not recruiting NCT01618435 Phase 3
44 Thermographic Images as an Objective Method for Assessing the Efficacy of Steroidal Epidural Injections Not yet recruiting NCT02725723 Phase 2, Phase 3
45 A Study of the In-Space Device for Treatment of Moderate Spinal Stenosis Terminated NCT00697827 Phase 3
46 DIAM™ Spinal Stabilization System vs. Decompression, Formerly vs. Posterolateral Fusion Terminated NCT00627497 Phase 3
47 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
48 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
49 Normal Pressure Hydrocephalus Treatment by Acetazolamide Terminated NCT02163330 Phase 3
50 Surgical Management of Spinal Cord Injuries In Neck Unknown status NCT00475748 Phase 2

Search NIH Clinical Center for Spinal Stenosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Spinal Stenosis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Spinal Stenosis:
MPCs, mesenchymal precursor cells for bone fusion
Embryonic/Adult Cultured Cells Related to Spinal Stenosis:
Mesenchymal Precursor Cells (STRO-3 selected) PMIDs: 24438940 20528753

Cochrane evidence based reviews: spinal stenosis

Genetic Tests for Spinal Stenosis

Anatomical Context for Spinal Stenosis

MalaCards organs/tissues related to Spinal Stenosis:

39
Spinal Cord, Bone, Testes, Skin, Lung, Brain, Pituitary

The Foundational Model of Anatomy Ontology organs/tissues related to Spinal Stenosis:

18
Spinal Cord

Publications for Spinal Stenosis

Articles related to Spinal Stenosis:

(show top 50) (show all 691)
id Title Authors Year
1
Lumbar Spinal Muscles and Spinal Canal Study by MRI Three-Dimensional Reconstruction in Adult Lumbar Spinal Stenosis. ( 28087395 )
2017
2
Surgical management of lumbar spinal stenosis: a survey among Norwegian spine surgeons. ( 27848083 )
2017
3
Decompression Surgery Alone Versus Decompression Plus Fusion in Symptomatic Lumbar Spinal Stenosis: A Swiss Prospective Multi-center Cohort Study with 3 Years of Follow-up. ( 28092340 )
2017
4
The Influence of Single-level Versus Multilevel Decompression on the Outcome in Multisegmental Lumbar Spinal Stenosis: Analysis of the Lumbar Spinal Outcome Study (LSOS) Data. ( 28059949 )
2017
5
Two Portal Percutaneous Endoscopic Decompression for Lumbar Spinal Stenosis: Preliminary Study. ( 27114776 )
2016
6
A prospective randomized trial comparing anterior cervical discectomy and fusion versus plate-only open-door laminoplasty for the treatment of spinal stenosis in degenerative diseases. ( 27885472 )
2016
7
A comparison between different outcome measures based on "meaningful important differences" in patients with lumbar spinal stenosis. ( 27177468 )
2016
8
Cost-effectiveness of conservative versus surgical treatment strategies of lumbar spinal stenosis in the Swiss setting: analysis of the prospective multicenter Lumbar Stenosis Outcome Study (LSOS). ( 28040872 )
2016
9
Clinical outcome of lumbar spinal stenosis based on new classification according to hypertrophied ligamentum flavum. ( 27580526 )
2016
10
Patient Priority Weighting of the Roland Morris Disability Questionnaire Does Not Change Results of the Lumbar Epidural Steroid Injections for Spinal Stenosis Trial. ( 27105466 )
2016
11
The effectiveness of decompression alone compared with additional fusion for lumbar spinal stenosis with degenerative spondylolisthesis: a pragmatic comparative non-inferiority observational study from the Norwegian Registry for Spine Surgery. ( 27421276 )
2016
12
No clinically important benefits of surgery over rehabilitation for lumbar spinal stenosis (PEDro synthesis). ( 27986763 )
2016
13
Enough positive rate of paraspinal mapping and diffusion tensor imaging with levels which should be decompressed in lumbar spinal stenosis. ( 27188929 )
2016
14
The paradoxicalA relationship between ligamentum flavum hypertrophy and developmental lumbar spinal stenosis. ( 27635416 )
2016
15
Efficacy of intraoperative direct electrical stimulation of the spinal root and measurement of distal motor latency in lumbar spinal stenosis. ( 27613011 )
2016
16
Lumbar Spinal Stenosis. ( 27145444 )
2016
17
In Patients with Lumbar Spinal Stenosis, Adding Fusion Surgery to Decompression Surgery Did Not Improve Outcomes at 2 Years. ( 27852913 )
2016
18
Changes in HbA1c levels and body mass index after successful decompression surgery in patients with type 2 diabetes mellitus and lumbar spinal stenosis: results of a two-year follow-up study. ( 27612595 )
2016
19
Intrapleural placement of a thoracic epidural catheter in a patient with spinal stenosis. ( 27871519 )
2016
20
Suprapedicular Foraminal Endoscopic Approach to Lumbar Lateral Recess Decompression Surgery to Treat Degenerative Lumbar Spinal Stenosis. ( 27890911 )
2016
21
Microsurgical unilateral laminotomy for decompression of lumbar spinal stenosis: long-term results and predictive factors. ( 27084380 )
2016
22
Multifidus Degeneration, a New Risk Factor for Lumbar Spinal Stenosis: A Case-Control Study. ( 27931946 )
2016
23
Reducing surgical levels by paraspinal mapping and diffusion tensor imaging techniques in lumbar spinal stenosis. ( 27113931 )
2016
24
Posterior decompression and internal fixation in treatment of hypertrophy of posterior longitudinal ligament at C1-2 level accompanied with lower cervical spinal stenosis: A case report. ( 27977597 )
2016
25
Letter to the editor: Microsurgical decompression for central lumbar spinal stenosis: a single-center observational study. ( 27644701 )
2016
26
Lumbar spondylosis, lumbar spinal stenosis, knee pain, back muscle strength are associated with the locomotive syndrome: Rural population study in Japan. ( 27021251 )
2016
27
Cauda equina conduction time determined by F-waves in normal subjects and patients with neurogenic intermittent claudication caused by lumbar spinal stenosis. ( 27753733 )
2016
28
Response to comments on "Microsurgical decompression for central lumbar spinal stenosis: a single-center observational study". ( 27663879 )
2016
29
Outcome after Surgery of Lumbar Spinal Stenosis: A Randomized Comparison of Bilateral Laminotomy, Trumpet Laminectomy, and Conventional Laminectomy. ( 27092304 )
2016
30
Analysis of the Relationship between Ligamentum Flavum Thickening and Lumbar Segmental Instability, Disc Degeneration, and Facet Joint Osteoarthritis in Lumbar Spinal Stenosis. ( 27994791 )
2016
31
Lumbar Spinal Stenosis: How Is It Classified? ( 27849674 )
2016
32
Diabetes Mellitus, a New Risk Factor for Lumbar Spinal Stenosis: A Case-Control Study. ( 27168730 )
2016
33
Minimally invasive surgery for lumbar spinal stenosis. ( 27659170 )
2016
34
A novel use of the Spine Tango registry to evaluate selection bias in patient recruitment into clinical studies: an analysis of patients participating in the Lumbar Spinal Stenosis Outcome Study (LSOS). ( 27844227 )
2016
35
Effect of TENS Versus Placebo on Walking Capacity in Patients With Lumbar Spinal Stenosis: A Protocol for a Randomized Controlled Trial. ( 27660596 )
2016
36
The global alignment in patients with lumbar spinal stenosis: our experience using the EOS full-body images. ( 27573076 )
2016
37
Radiographic assessment of degenerative lumbar spinal stenosis: is MRI superior to CT? ( 27663702 )
2016
38
The effect of incidental dural lesions on outcome after decompression surgery for lumbar spinal stenosis: results of a multi-center study with 800 patients. ( 27125375 )
2016
39
Psychosocial Factors in Patients Indicated for Lumbar Spinal Stenosis Surgery. ( 27144540 )
2016
40
Cerebrospinal fluid dynamics at the lumbosacral level in patients with spinal stenosis: A pilot study. ( 27664416 )
2016
41
Epidural Corticosteroid Injections for Radiculopathy and Spinal Stenosis. ( 27136216 )
2016
42
Epidural Corticosteroid Injections for Radiculopathy and Spinal Stenosis. ( 27136215 )
2016
43
Persistent Symptoms After Anatomically Successful Surgery for Lumbar Spinal Stenosis. ( 27080753 )
2016
44
Conventional Supine MRI with a Lumbar Pillow - an Alternative to Weight-Bearing MRI for Diagnosing Spinal Stenosis?: A Cross-Sectional Study. ( 27584675 )
2016
45
A Diagnostic Algorithm for Eosinophilic Granulomatosis with Polyangiitis Initially Diagnosed as Lumbar Disc Hernia or Lumbar Spinal Stenosis: Personal Experience and Review of the Literature. ( 27549670 )
2016
46
Complications of spinal surgery for elderly patients with lumbar spinal stenosis in a super-aging country: An analysis of 8033 patients. ( 27646205 )
2016
47
Eidurographic Findings Following Percutaneous Epidural Adhesiolysis Failed to Correlate with Level of Pain Reduction in Patients with Lumbar Spinal Stenosis. ( 27651508 )
2016
48
Facet joint injection versus epidural steroid injection for lumbar spinal stenosis: intra-individual study. ( 27639917 )
2016
49
Degenerative lumbar spinal stenosis and physical functioning: an exploration of associations between self-reported measures and physical performance tests. ( 27846739 )
2016
50
A potential method for identifying dural ossification by measuring the degree of spinal stenosis in thoracic ossification of ligamentum flavum. ( 27959285 )
2016

Variations for Spinal Stenosis

Expression for Spinal Stenosis

Search GEO for disease gene expression data for Spinal Stenosis.

Pathways for Spinal Stenosis

Pathways related to Spinal Stenosis according to GeneCards Suite gene sharing:

(show all 17)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.6 ACAN BMP7 COL11A1 COL11A2 COL9A1 COL9A2
2
Show member pathways
13.18 ACAN COL11A1 COL11A2 COL9A1 COL9A2 COL9A3
3
Show member pathways
12.61 COL11A1 COL11A2 COL9A1 COL9A2 COL9A3 THBS2
4
Show member pathways
12.5 ACAN BMP7 COL11A1 COL11A2 COL9A1 COL9A2
5
Show member pathways
12.46 COL11A1 COL11A2 COL9A1 COL9A2 COL9A3 MMP3
6 12.38 COL9A1 COL9A2 COL9A3 THBS2
7
Show member pathways
11.98 ACAN BMP7 COL11A1 COL11A2 COL9A1 COL9A2
8
Show member pathways
11.88 COL9A1 COL9A2 COL9A3 THBS2
9 11.65 MMP3 TIMP1 TIMP2
10
Show member pathways
11.62 MMP3 THBS2 TIMP1 TIMP2
11 11.5 BMP7 CALCA TIMP1
12 11.47 MMP3 TIMP1 TIMP2
13 11.22 ACAN MMP3 TIMP2
14 11.21 ACAN COL9A1 COL9A2 COL9A3
15 11.18 COL9A1 COL9A2 COL9A3
16 11.09 COL9A1 COL9A3
17 10.96 TIMP1 TIMP2

GO Terms for Spinal Stenosis

Cellular components related to Spinal Stenosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.85 COL11A1 COL11A2 COL9A1 COL9A2 COL9A3 TIMP1
2 extracellular matrix GO:0031012 9.8 ACAN BMP7 COL11A1 MMP3 THBS2 TIMP1
3 extracellular region GO:0005576 9.73 ACAN BMP7 CALCA COL11A1 COL11A2 COL9A1
4 basement membrane GO:0005604 9.63 ACAN THBS2 TIMP1
5 collagen trimer GO:0005581 9.63 COL11A1 COL11A2 COL9A1 COL9A2 COL9A3 TIMP1
6 collagen type IX trimer GO:0005594 9.5 COL9A1 COL9A2 COL9A3
7 collagen type XI trimer GO:0005592 9.43 COL11A1 COL11A2
8 proteinaceous extracellular matrix GO:0005578 9.32 ACAN COL11A1 COL11A2 COL9A1 COL9A2 COL9A3
9 extracellular space GO:0005615 10.01 ACAN BMP7 CALCA COL11A1 MMP3 THBS2

Biological processes related to Spinal Stenosis according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.69 CALCA TIMP1 TIMP2
2 ossification GO:0001503 9.63 BMP7 COL11A1 COL11A2
3 skeletal system development GO:0001501 9.62 ACAN BMP7 COL11A2 COL9A2
4 collagen catabolic process GO:0030574 9.58 COL11A1 COL11A2 MMP3
5 collagen fibril organization GO:0030199 9.54 ACAN COL11A1 COL11A2
6 skeletal system morphogenesis GO:0048705 9.52 COL11A1 COL11A2
7 chondrocyte development GO:0002063 9.49 ACAN COL11A1
8 positive regulation of adenylate cyclase activity GO:0045762 9.48 CALCA TIMP2
9 extracellular matrix disassembly GO:0022617 9.46 ACAN MMP3 TIMP1 TIMP2
10 negative regulation of membrane protein ectodomain proteolysis GO:0051045 9.43 TIMP1 TIMP2
11 negative regulation of metallopeptidase activity GO:1905049 9.26 TIMP1 TIMP2
12 cartilage development GO:0051216 9.26 BMP7 COL11A1 COL11A2 TIMP1
13 extracellular matrix organization GO:0030198 9.02 ACAN COL11A1 COL9A1 COL9A2 COL9A3

Molecular functions related to Spinal Stenosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 enzyme inhibitor activity GO:0004857 9.26 TIMP1 TIMP2
2 metalloendopeptidase inhibitor activity GO:0008191 9.16 TIMP1 TIMP2
3 extracellular matrix structural constituent GO:0005201 9.13 ACAN COL11A1 COL11A2
4 extracellular matrix structural constituent conferring tensile strength GO:0030020 8.92 COL11A2 COL9A1 COL9A2 COL9A3

Sources for Spinal Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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