MCID: SPN032
MIFTS: 40

Spindle Cell Carcinoma malady

Cancer diseases category

Aliases & Classifications for Spindle Cell Carcinoma

About this section
Sources:
10Disease Ontology, 12DISEASES, 47Novoseek, 65UMLS, 59SNOMED-CT, 36MeSH, 42NCIt
See all sources

Aliases & Descriptions for Spindle Cell Carcinoma:

Name: Spindle Cell Carcinoma 10 12
Carcinoma, Spindle-Cell 65
 
Carcinoma Spindle Cell 47
Sarcomatoid Carcinoma 10


Classifications:



External Ids:

Disease Ontology10 DOID:4015
MeSH36 D002277
SNOMED-CT59 23109009, 65692009
NCIt42 C27004

Summaries for Spindle Cell Carcinoma

About this section
Disease Ontology:10 A squamous cell carcinoma that is usually composed of the squamous cell type and results in fusiform development of rapidly proliferating cells.

MalaCards based summary: Spindle Cell Carcinoma, also known as carcinoma, spindle-cell, is related to fibromatosis and adenoma. An important gene associated with Spindle Cell Carcinoma is VIM (Vimentin), and among its related pathways are Striated Muscle Contraction and Glucocorticoid receptor regulatory network. Affiliated tissues include kidney, skin and breast, and related mouse phenotypes are cardiovascular system and tumorigenesis.

Wikipedia:68 Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover... more...

Related Diseases for Spindle Cell Carcinoma

About this section

Diseases related to Spindle Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 329)
idRelated DiseaseScoreTop Affiliating Genes
1fibromatosis31.0SYP, VIM
2adenoma30.6ACTC1, MUC1, VIM
3mucinous tubular and spindle cell carcinoma11.0
4renal cell carcinoma10.5
5thyroiditis10.5
6rectum sarcomatoid carcinoma10.4
7thymus sarcomatoid carcinoma10.4
8mesothelioma10.4
9sarcomatoid squamous cell skin carcinoma10.4
10laryngitis10.4
11sarcoma10.4
12lymphangiomatosis10.3ACTC1, VIM
13gastric signet ring cell adenocarcinoma10.3ACTC1, VIM
14orbit embryonal rhabdomyosarcoma10.3MUC1, VIM
15thyroid carcinoma with thyrotoxicosis10.3MUC1, VIM
16iodine antenatal infection10.3ACTC1, VIM
17prostatitis10.3
18portal hypertension10.3MUC1, VIM
19differentiating neuroblastoma10.3MUC1, VIM
20translocation renal cell carcinoma10.3AMACR, VIM
21vulvar nodular hidradenoma10.3MUC1, VIM
22vulvar clear cell hidradenocarcinoma10.3MUC1, VIM
23subependymal giant cell astrocytoma10.3MUC1, VIM
24placental site trophoblastic tumor10.3ACTC1, MUC1
25hereditary myopathy with intranuclear filamentous10.3CDH1, VIM
26bladder urachal adenocarcinoma10.3MUC1, VIM
27splenic artery aneurysm10.3MUC1, PGR
28histidine metabolism disease10.3MUC1, VIM
29basaloid squamous cell carcinoma10.3CDH1, VIM
30esotropia10.3CDH1, VIM
31malignant cystic nephroma10.3MUC1, PGR
32infantile free sialic acid storage disease10.3DES, VIM
33cowden disease10.3ACTC1, PGR
34neuroendocrine carcinoma10.3
35large cell neuroendocrine carcinoma10.3
36blastoma10.3
37esophagitis10.3
38pulmonary blastoma10.3
39ameloblastic carcinoma10.3
40endometriosis of intestine10.3MUC1, PGR
41spinocerebellar ataxia10.3DES, MUC1
42apocrine sweat gland neoplasm10.3MUC1, PGR
43spigelian hernia-cryptorchidism syndrome10.3ACTC1, DES
44lymphoplasmacyte-rich meningioma10.3DES, MUC1
45dendritic cell thymoma10.3ACTC1, VIM
46microscopic colitis10.3ACTC1, PGR
47uterine corpus serous adenocarcinoma10.3DES, VIM
48infiltrating bladder lymphoepithelioma-like carcinoma10.3MUC1, VIM
49sinus cancer10.3MUC1, SYP
50fallopian tube serous papilloma10.3SYP, VIM

Graphical network of the top 20 diseases related to Spindle Cell Carcinoma:



Diseases related to spindle cell carcinoma

Symptoms for Spindle Cell Carcinoma

About this section

Drugs & Therapeutics for Spindle Cell Carcinoma

About this section

Drugs for Spindle Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Sunitinibapproved, investigationalPhase 2472341031-54-7, 557795-19-45329102
Synonyms:
(2S)-2-hydroxybutanedioic acid
1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-, (2S)-hydroxybutanedioate (1:1)
1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-, (2S)-hydroxybutanedioate (1:1)
326914-13-0
341031-54-7
5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID (2-DIETHYLAMINO-ETHYL)-AMIDE
557795-19-4
AC1NS62J
AC1O5CMQ
AKOS005145765
Butanedioic acid, hydroxy-, (2S)-, compd. with N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (1:1)
CHEBI:38940
CHEBI:550864
CHEMBL1567
CHEMBL535
CID5329102
CID6456015
D06402
D08552
DB01268
DB07417
EN002687
FT-0083555
FT-0083556
I01-1229
K00588a
KS-5022
LS-186078
LS-187023
LS-187648
MolPort-003-986-763
N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-hydroxybutanedioate
N-(2-diethylaminoethyl)-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
NCGC00164631-01
 
NSC736511
NSC750690
PDGF TK antagonist
PHA-290940AD
PNU-290940AD
S1042_Selleck
ST51053712
SU 011248
SU 11248
SU-010398
SU-011248 L-malate salt
SU-11248
SU-11248 L-malate salt
SU-11248J
SU-12662
SU010398
SU011248
SU011248 L-malate salt
SU11248
Su-011248
Sunitanib
Sunitinib
Sunitinib (INN)
Sunitinib (free base)
Sunitinib Malate
Sunitinib malate
Sunitinib malate (JAN/USAN)
Sunitinib malate [USAN]
Sunitinibum
Sutent
Sutent (TN)
Sutent, SU-11248
TL8002546
UNII-LVX8N1UT73
UNII-V99T50803M
sunitinib
sunitinibum
2
GemcitabineapprovedPhase 2180095058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine Hydrochloride
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
3
FluorouracilapprovedPhase 2193751-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
4
Bevacizumabapproved, investigationalPhase 21820216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
5
Capecitabineapproved, investigationalPhase 21179154361-50-960953
Synonyms:
(1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester
154361-50-9
158798-73-3
5'-Deoxy-5-fluoro-N-((pentyloxy)carbonyl)cytidine
5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
AC1L1U83
AC1Q4KU8
Ambap154361-50-9
C110904
C12650
C15H22FN3O6
CAPE
CAPECITABINE
CHEBI:31348
CHEMBL1773
CID60953
Capecitabin
Capecitabina
Capecitabine
Capecitabine (JAN/USAN/INN)
Capecitabine [USAN]
Capecitabinum
Capecitibine
Capiibine
Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester
Caxeta
 
D01223
DB01101
FT-0082472
HSDB 7656
LS-59070
MolPort-005-938-254
N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine
Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate
Pentyl [1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
R-340
R340
RG-340
Ro 09-1978
Ro 09-1978/000
Ro-09-1978
Ro-09-1978/000
S1156_Selleck
UNII-6804DJ8Z9U
Xabine
Xeloda
Xeloda (TN)
Xeloda, Captabin, Capecitabine
ZINC03806413
capecitabina
capecitabine
capecitabinum
pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate
6
PaclitaxelapprovedPhase 2250533069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel

Interventional clinical trials:

idNameStatusNCT IDPhase
1Capecitabine, Gemcitabine, and Bevacizumab in Combination for Patients With Sarcomatoid Renal Cell CarcinomaActive, not recruitingNCT00496587Phase 2
2Trial Of Sunitinib In Advanced Non-Clear Cell Type Renal Cell CarcinomaActive, not recruitingNCT01219751Phase 2
3Alisertib in Chemotherapy-pretreated Urothelial CancerNot yet recruitingNCT02109328Phase 2

Search NIH Clinical Center for Spindle Cell Carcinoma

Genetic Tests for Spindle Cell Carcinoma

About this section

Anatomical Context for Spindle Cell Carcinoma

About this section

MalaCards organs/tissues related to Spindle Cell Carcinoma:

33
Kidney, Skin, Breast, Lung, Tongue, Thyroid, Pancreas

Animal Models for Spindle Cell Carcinoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Spindle Cell Carcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.8ACTC1, CDH1, CHGA, DES, PGR, TP63
2MP:00020067.8CDH1, KRT14, MUC1, PGR, TP63
3MP:00107717.5CDH1, KRT14, KRT5, MUC1, PGR, TP63
4MP:00053766.3ACTC1, AMACR, CDH1, CHGA, DES, KRT14
5MP:00107686.2ACTC1, AMACR, CDH1, CHGA, DES, KRT14

Publications for Spindle Cell Carcinoma

About this section

Articles related to Spindle Cell Carcinoma:

(show top 50)    (show all 264)
idTitleAuthorsYear
1
Laryngeal spindle cell carcinoma: A population-based analysis of incidence and survival. (25994520)
2015
2
Spindle cell carcinoma arising at the buccal mucosa: a case report and review of the literature. (25547144)
2015
3
A Case of Granulocyte-Colony Stimulating Factor-Producing Spindle Cell Carcinoma of the Breast. (25823685)
2015
4
Wide expression of ZEB1 in sarcomatous component of spindle cell carcinoma of the esophagus. (26515382)
2015
5
Low-grade fibromatosis-like spindle cell carcinomas of the breast are molecularly exiguous. (25713418)
2015
6
Merkel cell carcinoma with glandular differentiation admixed with sweat gland carcinoma and spindle cell carcinoma: histogenesis of merkel cell carcinoma from hair follicle stem cells. (25699980)
2015
7
Sarcomatoid (spindle cell) carcinoma of tongue: a report of two cases. (25785207)
2015
8
(18)F-fluorodeoxyglucose-positron-emission tomography/computed tomography staging of mucinous tubular and spindle cell carcinoma of the kidney. (25589812)
2015
9
Clinicopathological and immunohistochemical analysis of spindle cell carcinoma of the larynx or hypopharynx: A report of three cases. (25013496)
2014
10
Spindle cell carcinoma of the upper aerodigestive tract: an analysis of 341 cases with comparison to conventional squamous cell carcinoma. (24634155)
2014
11
Management of spindle cell carcinoma of the maxillary sinus: a case report and literature review. (25350698)
2014
12
Spindle cell carcinoma of the breast as complex cystic lesion: a case report. (25009755)
2014
13
Spindle cell carcinoma of the tongue: a rare variant of squamous cell carcinoma. (25114719)
2014
14
Clear cell changes in mucinous tubular and spindle cell carcinoma: cytoplasmic pallor/clearing within tubules, vacuoles or hybrid conventional clear cell carcinoma of kidney? (25120820)
2014
15
The imaging and pathological features of a mucinous tubular and spindle cell carcinoma of the kidney: a case report. (23374174)
2013
16
Metastatic renal mucinous tubular and spindle cell carcinoma. Atypical behavior of a rare, morphologically bland tumor. (21684183)
2012
17
Spindle cell carcinoma of the lung. (21308442)
2011
18
A case of esophageal spindle cell carcinoma. (21957183)
2011
19
Combined large cell neuroendocrine carcinoma and spindle cell carcinoma of the lung. (21415004)
2011
20
N-cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck region. (21070371)
2011
21
Post irradiation spindle cell carcinoma of tonsillar pillar. (22203850)
2011
22
Clinicopathological and immunohistochemical features of oral spindle cell carcinoma. (20002980)
2010
23
Mucinous tubular and spindle cell carcinoma of the kidney. (20022029)
2010
24
Fine needle aspiration cytology of spindle cell carcinoma of the tongue: a case report with emphasis on the diagnostic difficulties. (18691220)
2010
25
Sarcomatoid (spindle cell) carcinoma of the head and neck mucosal region: a clinicopathologic review of 103 cases from a tertiary referral cancer centre. (20730609)
2010
26
Spindle cell lesions--neoplastic or non-neoplastic?: spindle cell carcinoma and other atypical spindle cell lesions of the head and neck. (20614332)
2008
27
Cadherin-catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck. (18712413)
2008
28
Invasive spindle cell carcinoma of the conjunctiva managed by full-thickness eye wall resection. (17721310)
2007
29
Spindle cell carcinoma of the oral cavity and oropharynx: factors affecting outcome. (17098672)
2006
30
A 15-year-old girl with a spindle cell carcinoma of the parotid gland. A diagnostic challenge solved by immunohistochemistry and cytogenetic analysis. (16308263)
2006
31
Renal mucinous and tubular spindle cell carcinoma: a clinicopathological study of 4 cases. (17396379)
2006
32
Frequent expression of neuroendocrine markers in mucinous tubular and spindle cell carcinoma of the kidney. (16267782)
2006
33
Expanding the histologic spectrum of mucinous tubular and spindle cell carcinoma of the kidney. (17122511)
2006
34
H-ras mutation is an additional event of sarcomatous transformation in aerodigestive spindle cell carcinoma. (14767509)
2004
35
Spindle cell carcinoma of the intrahepatic bile duct in a patient with primary sclerosing cholangitis. (14673729)
2003
36
Wide spectrum screening keratin as a marker of metaplastic spindle cell carcinoma of the breast: an immunohistochemical study of 24 patients. (12047767)
2002
37
So-called carcinosarcoma of the gallbladder; spindle cell carcinoma of the gallbladder: report of a case. (12061703)
2002
38
Combined large cell neuroendocrine carcinoma and spindle cell carcinoma of the lung. (11510007)
2001
39
Spindle cell carcinoma of the oral cavity. Report o f a case. (11507539)
2000
40
Synchronous glottic granular cell tumor and subglottic spindle cell carcinoma. (9738817)
1998
41
A combined small cell and spindle cell carcinoma of the lung. Report of a unique case with immunohistochemical and ultrastructural studies. (1335211)
1992
42
Spindle-cell carcinoma of the oral cavity and larynx. Immunohistochemical aspects. (2474578)
1989
43
Metaplastic carcinomas of the breast. II. Spindle cell carcinoma. (2473024)
1989
44
Undifferentiated spindle cell carcinoma of the thyroid in a dog. (3962088)
1986
45
The controversial role of radiotherapy in spindle cell carcinoma (pseudosarcoma) of the head and neck. (3836441)
1985
46
Oral findings of a spindle-cell carcinoma of the maxillary alveolar ridge. (3928707)
1985
47
Metastatic spindle-cell carcinoma. Cytologic features and differential diagnosis. (3859145)
1985
48
Spindle cell carcinoma of the hamster trachea induced by N-methyl-N-nitrosourea. (6837722)
1983
49
Spindle cell carcinoma of the vulva. (7117117)
1982
50
Spindle-cell carcinoma of the laryngopharynx. (720254)
1978

Variations for Spindle Cell Carcinoma

About this section

Expression for genes affiliated with Spindle Cell Carcinoma

About this section
Search GEO for disease gene expression data for Spindle Cell Carcinoma.

Pathways for genes affiliated with Spindle Cell Carcinoma

About this section

Pathways related to Spindle Cell Carcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5ACTC1, DES, VIM
28.7CHGA, KRT14, KRT5
3
Show member pathways
8.6DES, KRT14, KRT5, VIM
48.5ACTC1, CDH1, DES, KRT5, VIM

GO Terms for genes affiliated with Spindle Cell Carcinoma

About this section

Cellular components related to Spindle Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058828.6DES, KRT14, KRT5, VIM

Biological processes related to Spindle Cell Carcinoma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697810.1MUC1, TP63
2regulation of epithelial cell proliferationGO:005067810.0CDH1, PGR
3muscle filament slidingGO:00300499.5ACTC1, DES, VIM
4hemidesmosome assemblyGO:00315819.3KRT14, KRT5
5epidermis developmentGO:00085448.9KRT14, KRT5, TP63
6epithelial cell differentiationGO:00308558.6KRT14, MUC1, TP63
7cell junction assemblyGO:00343298.6CDH1, KRT14, KRT5

Molecular functions related to Spindle Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filament bindingGO:19902549.8KRT14, VIM
2structural constituent of cytoskeletonGO:00052008.6DES, KRT14, KRT5, VIM
3structural molecule activityGO:00051988.3DES, KRT14, KRT5, VIM

Sources for Spindle Cell Carcinoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet