MCID: SPN012
MIFTS: 33

Spindle Cell Hemangioma malady

Cardiovascular diseases, Fetal diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Spindle Cell Hemangioma

About this section
Sources:
10Disease Ontology, 12DISEASES, 51Orphanet, 65UMLS, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all sources

Aliases & Descriptions for Spindle Cell Hemangioma:

Name: Spindle Cell Hemangioma 10 12 51 65
Spindle Cell Hemangioendothelioma 10 51
 
Spindle Cell Angioendothelioma 10
Sch 10


Classifications:



External Ids:

Disease Ontology10 DOID:496
NCIt42 C4754
Orphanet51 210584
ICD10 via Orphanet28 D18.0
UMLS via Orphanet66 C1304508

Summaries for Spindle Cell Hemangioma

About this section
Wikipedia:68 Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign as... more...

MalaCards based summary: Spindle Cell Hemangioma, also known as spindle cell hemangioendothelioma, is related to hemangioma and hemangioendothelioma. An important gene associated with Spindle Cell Hemangioma is IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble), and among its related pathways is Peroxisome. Affiliated tissues include cervix and bone.

Related Diseases for Spindle Cell Hemangioma

About this section

Diseases related to Spindle Cell Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 490)
idRelated DiseaseScoreTop Affiliating Genes
1hemangioma10.8
2hemangioendothelioma10.5
3maffucci syndrome10.4
4drug rash with eosinophilia and systemic symptoms10.3
5asthma10.2
6hepatitis c virus10.2
7hepatitis10.2
8hepatitis c10.2
9central nervous system disease10.2
10alveolar periostitis10.2IDH1, IDH2
11malignant biphasic mesothelioma10.2IDH1, IDH2
12enchondromatosis dwarfism deafness10.2IDH1, IDH2
13congenital disorder of glycosylation, type if10.2IDH1, IDH2
14mixed astrocytoma-ependymoma10.2IDH1, IDH2
15small cell osteogenic sarcoma10.2IDH1, IDH2
16her2-receptor negative breast cancer10.2IDH1, IDH2
17lymphedema10.2
18ollier disease10.2
19periostitis10.2
20enchondroma10.2
21epithelioid hemangioendothelioma10.2
22peripheral vascular disease10.2
23hepatitis a10.2
24acquired immunodeficiency syndrome10.2
25human immunodeficiency virus infectious disease10.2
26nervous system cancer10.2
27obstructive lung disease10.2
28viral hepatitis10.2
29breast leiomyoma10.2IDH1, IDH2
30adult brain stem glioma10.2IDH1, IDH2
31choledochal cyst10.2IDH1, IDH2
32spindle cell carcinoma10.2IDH1, IDH2
33benign peritoneal mesothelioma10.2IDH1, IDH2
34dry eye syndrome10.2IDH1, IDH2
35gastric papillary adenocarcinoma10.2IDH1, IDH2
36parkinson disease, late-onset10.2
37hepatocellular carcinoma10.2
38asthma 110.2
39hepatitis b10.2
40cork-handlers' disease10.2
41basal ganglia disease10.2
42germ cell cancer10.2
43hypersensitivity reaction type iv disease10.2
44mouth disease10.2
45movement disease10.2
46oral cavity cancer10.2
47respiratory system disease10.2
48urinary system disease10.2
49adams-oliver syndrome10.2IDH1, IDH2
50microglandular adenosis of breast10.1IDH1, IDH2

Graphical network of the top 20 diseases related to Spindle Cell Hemangioma:



Diseases related to spindle cell hemangioma

Symptoms for Spindle Cell Hemangioma

About this section

Drugs & Therapeutics for Spindle Cell Hemangioma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Hemangioma

Genetic Tests for Spindle Cell Hemangioma

About this section

Anatomical Context for Spindle Cell Hemangioma

About this section

MalaCards organs/tissues related to Spindle Cell Hemangioma:

33
Cervix, Bone

Animal Models for Spindle Cell Hemangioma or affiliated genes

About this section

Publications for Spindle Cell Hemangioma

About this section

Articles related to Spindle Cell Hemangioma:

(show all 17)
idTitleAuthorsYear
1
Expression of Prox1, D2-40, and WT1 in spindle cell hemangioma. (24673328)
2014
2
R132C IDH1 mutations are found in spindle cell hemangiomas and not in other vascular tumors or malformations. (23485734)
2013
3
Periosteal spindle cell hemangioma of the fibula: a case report. (23525489)
2013
4
Maffucci syndrome with the spindle cell hemangiomas in the mucosa of the lower lip: a rare case report and literature review. (23506121)
2013
5
Spindle-cell hemangioma (spindle-cell hemangioendothelioma): a diagnosis on fine-needle aspiration cytology. (22927295)
2012
6
Spindle cell hemangioma reoccurrence in the hand: case report. (23730241)
2012
7
Intraosseous spindle cell hemangioma of the calcaneus: a case report and review of the literature. (22534243)
2012
8
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. (22057234)
2011
9
Spindle cell hemangioma of the calf with myxoid stroma and pseudolipoblasts. (20860749)
2010
10
Spindle cell hemangioma (hemangioendothelioma) of the head and neck: case report of an unusual (or underdiagnosed) tumor. (17656123)
2008
11
Spindle cell hemangioma: report of a case presenting in the oral cavity. (17880587)
2007
12
Spindle cell hemangioma and epithelioid hemangioendothelioma arising in an area of lymphedema. (16778491)
2006
13
Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor? (16630186)
2006
14
Huge spindle cell hemangioma of the cervix--mimicking a pelvic tumor. (15860919)
2005
15
Spindle cell hemangioma. (12859394)
2003
16
Hemorrhagic epithelioid and spindle cell hemangioma: a newly recognized, unique vascular tumor of bone. (10223237)
1999
17
Spindle cell hemangioma. (10592415)
1999

Variations for Spindle Cell Hemangioma

About this section

Expression for genes affiliated with Spindle Cell Hemangioma

About this section
Search GEO for disease gene expression data for Spindle Cell Hemangioma.

Pathways for genes affiliated with Spindle Cell Hemangioma

About this section

Pathways related to Spindle Cell Hemangioma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8IDH1, IDH2

GO Terms for genes affiliated with Spindle Cell Hemangioma

About this section

Biological processes related to Spindle Cell Hemangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glyoxylate cycleGO:000609710.2IDH1, IDH2
2isocitrate metabolic processGO:000610210.2IDH1, IDH2
3tricarboxylic acid cycleGO:000609910.0IDH1, IDH2
42-oxoglutarate metabolic processGO:00061039.5IDH1, IDH2
5regulation of cellular response to heatGO:19000349.1BAG1, BAG2

Molecular functions related to Spindle Cell Hemangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1isocitrate dehydrogenase (NADP+) activityGO:000445010.3IDH1, IDH2
2oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00166169.9IDH1, IDH2
3NAD bindingGO:00512879.9IDH1, IDH2
4chaperone bindingGO:00510879.1BAG1, BAG2

Sources for Spindle Cell Hemangioma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet