MCID: SPN006
MIFTS: 37

Spindle Cell Lipoma malady

Category: Cancer diseases

Aliases & Classifications for Spindle Cell Lipoma

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Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:10184
SNOMED-CT59 27313007, 404058008
NCIt42 C4254
UMLS65 C0334474

Summaries for Spindle Cell Lipoma

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Disease Ontology:10 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary: Spindle Cell Lipoma is related to fibrosarcoma and lipoma. An important gene associated with Spindle Cell Lipoma is RB1 (Retinoblastoma 1), and among its related pathways are TSH signaling pathway and FOXM1 transcription factor network. Affiliated tissues include breast, bone and lung, and related mouse phenotypes are pigmentation and cellular.

Wikipedia:68 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

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Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 102)
idRelated DiseaseScoreTop Affiliating Genes
1fibrosarcoma29.1CDK4, MDM2, RB1
2lipoma10.9
3pleomorphic lipoma10.6
4gingival hypertrophy10.3DES, VIM
5malignant teratocarcinosarcoma10.3DES, VIM
6spindle cell variant squamous cell breast carcinoma10.3DES, VIM
7vulvar angiokeratoma10.3DES, VIM
8uterine corpus adenocarcinofibroma10.3DES, VIM
9pulmonary venous return anomaly10.2ACTC1, DES
10benign deep fibrous histiocytoma10.2ACTC1, DES
11thymus lipoma10.2ACTC1, DES
1246xy sex reversal 510.2DES, VIM
13proliferative fasciitis10.2ACTC1, DES
14absence of fingerprints congenital milia10.2ACTC1, VIM
15renal tubular acidosis, distal, autosomal recessive10.1DES, VIM
16familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.1ACTC1, VIM
17ovarian mucinous cystadenocarcinoma10.1ACTC1, VIM
18liposarcoma10.1
19solitary fibrous tumor10.1
20cellular schwannoma10.0DES, VIM
21facial injuries and disorders10.0MDM2, RB1
22transverse vaginal septum10.0ACTC1, DES
23dermatofibrosarcoma protuberans10.0
24atypical lipomatous tumor10.0
25angiolipoma10.0CDK4, MDM2
26fibrosarcoma of bone9.9CDK4, MDM2
27small cell osteogenic sarcoma9.9CDK4, MDM2
28epithelioid sarcoma9.9CDK4, MDM2
29uveal diseases9.9DES, MDM2
30sclerosing liposarcoma9.9CDK4, MDM2
31extrahepatic bile duct lipoma9.9CDK4, MDM2
32liver rhabdomyosarcoma9.9DES, MDM2
33epidural spinal canal angiolipoma9.9CDK4, MDM2
34tendon sheath lipoma9.9CDK4, MDM2
35merrf syndrome9.9CDK4, MDM2
36peripheral osteosarcoma9.9CDK4, MDM2
37desmoplastic infantile astrocytoma9.9ACTC1, DES, RB1
38visual cortex disease9.8CDK4, MDM2
39fibroma9.8
40cervicitis9.8
41pleomorphic adenoma9.8
42spindle cell liposarcoma9.8
43myositis9.8
44adenoma9.8
45myositis ossificans9.8
46dysphagia9.8
47calcified aponeurotic fibroma9.8
48sebaceous breast carcinoma9.8CDK4, MDM2
49retroperitoneum carcinoma9.8CDK4, MDM2
50congenital fibrosis of the extraocular muscles9.8ACTC1, DES, VIM

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to spindle cell lipoma

Symptoms for Spindle Cell Lipoma

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Drugs & Therapeutics for Spindle Cell Lipoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

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Anatomical Context for Spindle Cell Lipoma

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MalaCards organs/tissues related to Spindle Cell Lipoma:

33
Breast, Bone, Lung, Liver, T cells, Prostate, B cells

Animal Models for Spindle Cell Lipoma or affiliated genes

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MGI Mouse Phenotypes related to Spindle Cell Lipoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.0CDK4, MDM2, RB1
2MP:00053847.3ACTC1, CDK4, DES, MDM2, RB1, VIM
3MP:00053767.1ACTC1, CDK4, DES, MDM2, RB1, VIM
4MP:00053857.1ACTC1, CDK4, DES, MDM2, RB1, VIM
5MP:00053697.0ACTC1, CDK4, DES, MDM2, RB1, VIM
6MP:00107686.8ACTC1, CDK4, DES, MDM2, RB1, VIM

Publications for Spindle Cell Lipoma

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Articles related to Spindle Cell Lipoma:

(show top 50)    (show all 153)
idTitleAuthorsYear
1
Spindle Cell Lipoma of the Neck: Review of the Literature and Case Report. (26893975)
2015
2
Rare occurrence of lip spindle cell lipoma. (25815220)
2015
3
"Low-Fat" Pseudoangiomatous Spindle Cell Lipoma: A Rare Variant With Loss of 13q14 Region. (25839893)
2015
4
"Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge. (26017060)
2015
5
Management of a Nasal Spindle Cell Lipoma: Diagnostic and Therapeutic Considerations. (26517318)
2015
6
Letter to the Editor: Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case. Response to Laliotis et al. (26017887)
2015
7
MR imaging features of spindle cell lipoma. (24240205)
2014
8
Spindle Cell Lipoma of the Orbit. (24819207)
2014
9
Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma:report of a case. (24166610)
2013
10
Transoral robotic surgery for huge spindle cell lipoma of the hypopharynx. (23851787)
2013
11
Spindle cell lipoma of the larynx. (23780614)
2013
12
Spindle cell lipoma: a rare tumor of the mediastinum. (23991327)
2013
13
Dysphagia caused by spindle cell lipoma of hypopharynx: presentation of clinical case and literature review. (23326743)
2012
14
Spindle cell lipoma: a case report and review of literature. (23132485)
2012
15
Spindle cell lipoma with collagen rosettes. (21645033)
2011
16
Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma. (20852591)
2011
17
An unusual and spectacular case of spindle cell lipoma of the posterior neck invading the spinal cervical canal and posterior cranial fossa. (21819187)
2011
18
Spindle cell lipoma of the orbit: a case report of an unusual orbital pathology. (20827617)
2010
19
Cutaneous CD34+ spindle cell neoplasms: Histopathologic features distinguish spindle cell lipoma, solitary fibrous tumor, and dermatofibrosarcoma protuberans. (20559119)
2010
20
Left supraclavicular spindle cell lipoma. (20508829)
2010
21
Spindle cell lipoma of the aortic valve: a rare cardiac finding. (19010061)
2010
22
Infantile fibrosarcoma successfully treated with chemotherapy, with occurrence of calcifying aponeurotic fibroma and pleomorphic/spindled celled lipoma at the site 12 years later. (19648795)
2009
23
Infiltrating intramuscular spindle cell lipoma of the face. (19187113)
2009
24
Spindle cell lipoma breast. (18603691)
2008
25
Spindle cell lipoma of the spermatic cord. (17956535)
2007
26
CD10 is expressed by mammary myofibroblastoma and spindle cell lipoma of soft tissue: an additional evidence of their histogenetic linking. (17497167)
2007
27
Spindle cell lipoma of the floor of the mouth. A case report. (16878055)
2006
28
Pathology quiz case 2. Spindle cell lipoma. (16490884)
2006
29
Synchronous ordinary lipoma and spindle-cell lipoma diagnosed by fine needle aspiration. (16680778)
2006
30
Spindle cell lipoma showing biphasic pattern--a case report. (16075897)
2005
31
Spindle cell lipoma of the floor of the mouth: report of a case. (15917181)
2005
32
Spindle cell lipoma of the knee: a case report. (14767709)
2004
33
Dermal spindle cell lipoma of the posterior neck: CT and MR findings. (15018196)
2003
34
Imaging characteristics of spindle cell lipoma. (14573414)
2003
35
Intramuscular dendritic fibromyxolipoma: myxoid variant of spindle cell lipoma? (12675771)
2003
36
Spindle cell lipoma of the hypopharynx. (11453572)
2001
37
Spindle-cell lipoma of the cheek: a case report. (10964060)
2000
38
Pleomorphic lipoma with pseudopapillary structures: a pleomorphic counterpart of pseudoangiomatous spindle cell lipoma. (10792493)
2000
39
Fine-needle aspiration diagnosis of spindle-cell lipoma: a case report and review of the literature. (11074636)
2000
40
Myofibroblastoma of the breast: genetic link with spindle cell lipoma. (10878550)
2000
41
Spindle-cell lipoma of the preseptal eyelid. (9612807)
1998
42
Angiomyofibroblastomalike tumor of the male genital tract: analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma. (9422311)
1998
43
Spindle cell lipoma--a pseudoangiomatous variant. (8063285)
1994
44
Spindle cell lipoma within the larynx: a case report with correlated light and electron microscopy. (8321547)
1993
45
Spindle cell lipoma of the breast: a case report and literature review. (8261850)
1993
46
Spindle-cell lipoma: an unusual oral presentation. (2512544)
1989
47
Large intramuscular spindle-cell lipoma. With review of the literature. A case report. (3285867)
1988
48
Spindle cell lipoma. (6487132)
1984
49
Spindle-cell lipoma. A clinical, light- and electron-microscopical study. (7282993)
1981
50
Spindle cell lipoma (report of 2 cases and differential diagnosis). (205204)
1977

Variations for Spindle Cell Lipoma

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Expression for genes affiliated with Spindle Cell Lipoma

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Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for genes affiliated with Spindle Cell Lipoma

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Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 26)
idSuper pathwaysScoreTop Affiliating Genes
19.5CDK4, RB1
29.5CDK4, RB1
3
Show member pathways
9.5DES, VIM
49.2MDM2, RB1
59.2MDM2, RB1
69.2MDM2, RB1
79.1CDK4, MDM2
89.1CDK4, MDM2
99.0CDK4, RB1, VIM
108.9ACTC1, DES, VIM
118.7MDM2, RB1, VIM
128.7CDK4, MDM2, RB1
13
Show member pathways
8.7CDK4, MDM2, RB1
14
Show member pathways
8.7CDK4, MDM2, RB1
15
Show member pathways
8.7CDK4, MDM2, RB1
168.7CDK4, MDM2, RB1
17
Show member pathways
8.7CDK4, MDM2, RB1
18
Show member pathways
8.7CDK4, MDM2, RB1
198.7CDK4, MDM2, RB1
208.7CDK4, MDM2, RB1
21
Show member pathways
8.7CDK4, MDM2, RB1
228.7CDK4, MDM2, RB1
238.7CDK4, MDM2, RB1
24
Show member pathways
8.7CDK4, MDM2, RB1
25
Show member pathways
8.7CDK4, MDM2, RB1
268.7CDK4, MDM2, RB1

GO Terms for genes affiliated with Spindle Cell Lipoma

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Cellular components related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.5DES, VIM

Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of cell cycleGO:00517269.5CDK4, RB1
2muscle filament slidingGO:00300499.5ACTC1, VIM
3response to toxic substanceGO:00096368.8CDK4, MDM2

Sources for Spindle Cell Lipoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet