MCID: SPN006
MIFTS: 35

Spindle Cell Lipoma malady

Categories: Cancer diseases

Aliases & Classifications for Spindle Cell Lipoma

Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10184
NCIt 47 C4254
SNOMED-CT 64 27313007 404058008
UMLS 69 C0334474

Summaries for Spindle Cell Lipoma

Disease Ontology : 12 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary : Spindle Cell Lipoma is related to pleomorphic lipoma and lipoma. An important gene associated with Spindle Cell Lipoma is DES (Desmin), and among its related pathways/superpathways are Pathways in cancer and Chks in Checkpoint Regulation. Affiliated tissues include breast, tongue and bone, and related phenotypes are cardiovascular system and cellular

Wikipedia : 71 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
id Related Disease Score Top Affiliating Genes
1 pleomorphic lipoma 11.3
2 lipoma 10.8
3 oral erosive lichen 10.2 ACTC1 DES
4 carbon monoxide-induced parkinsonism 10.2 ACTC1 DES
5 vagina leiomyosarcoma 10.2 ACTC1 DES
6 inflammatory linear verrucous epidermal nevus 10.2 DES VIM
7 lymphomatous thyroiditis 10.2 DES VIM
8 pustulosis palmaris et plantaris 10.2 ACTC1 DES
9 marfanoid hypermobility syndrome 10.2 DES VIM
10 adult endodermal sinus tumor 10.2 DES VIM
11 biliary papillomatosis 10.2 DES VIM
12 tanycytic ependymoma 10.2 DES VIM
13 lymphomatoid papulosis 10.2 ACTC1 VIM
14 chest wall parachordoma 10.2 ACTC1 VIM
15 liver angiosarcoma 10.2 DES VIM
16 cavernous sinus meningioma 10.2 DES VIM
17 male reproductive system disease 10.2 DES VIM
18 isolated anterior cervical hypertrichosis 10.2 ACTC1 VIM
19 petrous apex meningioma 10.2 DES VIM
20 tinea favosa 10.2 ACTC1 DES
21 vulvar squamous papilloma 10.2 DES VIM
22 anal gland neoplasm 10.2 DES VIM
23 conjunctival cancer 10.2 ACTC1 VIM
24 skin glomus tumor 10.2 DES VIM
25 testicular granulosa cell tumor 10.1 ACTC1 VIM
26 congenital muscular dystrophy with hyperlaxity 10.1 DES VIM
27 lymphangiosarcoma 10.1 ACTC1 VIM
28 hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 10.1 ACTC1 VIM
29 cauda equina intradural extramedullary astrocytoma 10.1 ACTC1 VIM
30 gangliosidosis gm1 10.1 ACTC1 DES
31 extracutaneous mastocytoma 10.1 DES RB1
32 spindle cell rhabdomyosarcoma 10.1 ACTC1 DES
33 jewett-marshall bladder cancer 10.1 DES VIM
34 growth retardation hydrocephaly lung hypoplasia 10.1 ACTC1 VIM
35 ostertagiasis 10.1 ACTC1 DES
36 desmoid tumor 10.1 ACTC1 VIM
37 popliteal pterygium syndrome, bartsocas-papas type 10.1 ACTC1 VIM
38 ossifying fibromyxoid tumor 10.1 CDK4 VIM
39 sengers syndrome 10.1 DES VIM
40 c-p angle neurinoma 10.1 DES VIM
41 extranodal nasal nk/t cell lymphoma 10.1 CDK4 RB1
42 13q12.3 microdeletion syndrome 10.0 ACTC1 DES VIM
43 rommen mueller sybert syndrome 10.0 CDK4 MDM2
44 myoma 10.0 ACTC1 DES VIM
45 congenital myasthenic syndrome 10.0 ACTC1 DES VIM
46 spleen angiosarcoma 10.0 ACTC1 DES VIM
47 malignant dermis tumor 10.0 ACTC1 DES VIM
48 urethral cancer 10.0 ACTC1 DES VIM
49 biemond syndrome 10.0 ACTC1 DES VIM
50 intestinal obstruction 10.0 ACTC1 DES VIM

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to Spindle Cell Lipoma

Symptoms & Phenotypes for Spindle Cell Lipoma

MGI Mouse Phenotypes related to Spindle Cell Lipoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.85 ACTC1 CDK4 DES MDM2 RB1 VIM
2 cellular MP:0005384 9.8 ACTC1 CDK4 DES MDM2 RB1 VIM
3 homeostasis/metabolism MP:0005376 9.73 ACTC1 CDK4 DES MDM2 RB1 VIM
4 mortality/aging MP:0010768 9.63 RB1 VIM ACTC1 CDK4 DES MDM2
5 muscle MP:0005369 9.43 ACTC1 CDK4 DES MDM2 RB1 VIM
6 pigmentation MP:0001186 8.8 CDK4 MDM2 RB1

Drugs & Therapeutics for Spindle Cell Lipoma

Search Clinical Trials , NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

Anatomical Context for Spindle Cell Lipoma

MalaCards organs/tissues related to Spindle Cell Lipoma:

39
Breast, Tongue, Bone, Skin

Publications for Spindle Cell Lipoma

Articles related to Spindle Cell Lipoma:

(show top 50) (show all 162)
id Title Authors Year
1
Cytogenetic Analysis of a Pseudoangiomatous Pleomorphic/Spindle Cell Lipoma. ( 28476785 )
2017
2
Cytohistological Features of Spindle Cell Lipoma- A Case Report with Differential Diagnosis. ( 28384874 )
2017
3
Spindle Cell Lipoma in Dogs. ( 28494701 )
2017
4
Pseudoangiomatous Spindle Cell Lipoma: a distinct subtype of spindle cell lipoma. ( 27982506 )
2016
5
Dermal plexiform spindle cell lipoma. ( 27833986 )
2016
6
S-100 protein expressing spindle cells in spindle cell lipoma: a diagnostic pitfall. ( 27444171 )
2016
7
Pseudoangiomatous variant of spindle cell lipoma: Report of a rare case. ( 27510682 )
2016
8
Low-Fat Plexiform Spindle Cell Lipoma With Prominent Myxoid Stroma: An Unusual Oral Presentation and Immunohistochemical Analysis. ( 28045832 )
2016
9
Spindle Cell Lipoma in an End-Stage Renal Allograft: Case Report. ( 27932168 )
2016
10
Spindle cell lipoma of the soft palate. ( 25878917 )
2015
11
Acute dyspnea caused by a giant spindle cell lipoma of the larynx. ( 26438102 )
2015
12
Oral Spindle Cell Lipoma in a Rare Location: A Differential Diagnosis. ( 26615969 )
2015
13
Spindle cell lipoma with predominant nerve sheath tumor-like areas: A potential diagnostic pitfall on aspiration cytology. ( 26457887 )
2015
14
"Low-Fat" Pseudoangiomatous Spindle Cell Lipoma: A Rare Variant With Loss of 13q14 Region. ( 25839893 )
2015
15
Spindle Cell Lipoma of the Neck: Review of the Literature and Case Report. ( 26893975 )
2015
16
Spindle Cell Lipoma Occurring in the Buccal Mucosa: An Unusual Location of This Benign Lipomatous Neoplasm. ( 26491592 )
2015
17
Management of a Nasal Spindle Cell Lipoma: Diagnostic and Therapeutic Considerations. ( 26517318 )
2015
18
Spindle cell lipoma of the wrist, occurring in a distinctly rare location: a case report with review of literature. ( 26045856 )
2015
19
Spindle cell lipoma of the tongue. ( 25682756 )
2015
20
Rare occurrence of lip spindle cell lipoma. ( 25815220 )
2015
21
Intramuscular spindle cell lipoma of the deltoid: a case report. ( 25880875 )
2015
22
"Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge. ( 26017060 )
2015
23
Diagnostically challenging case of low-fat spindle cell lipoma. ( 26053070 )
2015
24
Folliculosebaceous Cystic Hamartoma With Spindle Cell Lipoma-Like Stromal Features. ( 26588344 )
2015
25
Letter to the Editor: Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case. Response to Laliotis et al. ( 26017887 )
2015
26
Dendritic fibromyxolipoma: a variant of spindle cell lipoma with extensive myxoid change, with cytogenetic evidence. ( 25047505 )
2014
27
Re: co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma. Report of a case. ( 25119179 )
2014
28
A rare case of spindle cell lipoma of broad ligament presenting as a pelvic mass. ( 25422813 )
2014
29
Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. ( 24659226 )
2014
30
RE: "Fat-free" spindle cell lipoma in retropharynx. ( 24843246 )
2014
31
Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature. ( 25319950 )
2014
32
Spindle cell lipoma of the mandibular mucogingival junction: a case report of unusual oral neoplasm. ( 24556953 )
2014
33
Spindle cell lipoma adherent to the digital nerve in the palm. ( 25414563 )
2014
34
Spindle Cell Lipoma of the Orbit. ( 24819207 )
2014
35
MR imaging features of spindle cell lipoma. ( 24240205 )
2014
36
Spindle Cell Lipoma of the Conjunctiva. ( 24911538 )
2014
37
Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case Ivan Chernev, Shane Mctighe, Dirk P. Stanley. ( 25372424 )
2014
38
Imaging characteristics of spindle cell lipoma and its variants. ( 24554024 )
2014
39
Myofibroblastoma of the female breast with admixed but distinct foci of spindle cell lipoma: a case report. ( 24459597 )
2013
40
Transoral robotic surgery for huge spindle cell lipoma of the hypopharynx. ( 23851787 )
2013
41
Spindle cell lipoma of the tongue: A case report of unusual occurrence. ( 23798855 )
2013
42
Spindle cell lipoma: a rare tumor of the mediastinum. ( 23991327 )
2013
43
Subungual spindle cell lipoma. ( 22171806 )
2013
44
Spindle cell lipoma of the head and neck: CT and MR imaging findings. ( 23053001 )
2013
45
Fine needle aspiration biopsy of intraparotid spindle cell lipoma: a case report. ( 22021087 )
2013
46
Spindle cell lipoma. ( 23946512 )
2013
47
Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma:report of a case. ( 24166610 )
2013
48
Spindle cell lipoma of the larynx. ( 23780614 )
2013
49
Spindle cell lipoma masquerading as lipomatous pleomorphic adenoma: A diagnostic dilemma on fine needle aspiration cytology. ( 23661944 )
2013
50
Spindle cell lipoma: a case report and review of literature. ( 23132485 )
2012

Variations for Spindle Cell Lipoma

Expression for Spindle Cell Lipoma

Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for Spindle Cell Lipoma

Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 29)
id Super pathways Score Top Affiliating Genes
1 12.41 CDK4 MDM2 RB1
2
Show member pathways
12.41 CDK4 MDM2 RB1
3
Show member pathways
12.31 CDK4 MDM2 RB1
4 12.26 ACTC1 DES VIM
5 12.16 CDK4 RB1 VIM
6
Show member pathways
12.15 CDK4 DES RB1
7
Show member pathways
12.1 CDK4 MDM2 RB1
8 12.08 CDK4 MDM2 RB1
9 12.01 MDM2 RB1 VIM
10 11.99 CDK4 MDM2 RB1
11
Show member pathways
11.94 CDK4 MDM2 RB1
12
Show member pathways
11.87 CDK4 MDM2 RB1
13 11.82 CDK4 MDM2 RB1
14
Show member pathways
11.76 CDK4 MDM2 RB1
15 11.72 CDK4 MDM2 RB1 VIM
16 11.66 CDK4 RB1 VIM
17 11.59 CDK4 MDM2 RB1
18
Show member pathways
11.56 CDK4 RB1
19 11.47 CDK4 RB1
20 11.44 CDK4 MDM2 RB1
21 11.38 MDM2 RB1
22 11.3 CDK4 MDM2 RB1
23
Show member pathways
11.27 DES VIM
24 11.25 CDK4 MDM2
25 11.19 ACTC1 DES VIM
26 11.16 CDK4 RB1
27 11.08 CDK4 MDM2
28 10.88 MDM2 RB1
29 10.46 CDK4 MDM2 RB1

GO Terms for Spindle Cell Lipoma

Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.61 MDM2 RB1 VIM
2 positive regulation of gene expression GO:0010628 9.54 ACTC1 MDM2 VIM
3 response to drug GO:0042493 9.5 ACTC1 CDK4 MDM2
4 negative regulation of neuron projection development GO:0010977 9.4 MDM2 VIM
5 positive regulation of cell cycle GO:0045787 9.26 CDK4 MDM2
6 negative regulation of cell cycle arrest GO:0071157 9.16 CDK4 MDM2
7 intermediate filament organization GO:0045109 8.96 DES VIM
8 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Molecular functions related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 9.16 MDM2 VIM
2 disordered domain specific binding GO:0097718 8.96 MDM2 RB1
3 identical protein binding GO:0042802 8.92 DES MDM2 RB1 VIM

Sources for Spindle Cell Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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