MCID: SPN006
MIFTS: 32

Spindle Cell Lipoma malady

Cancer diseases category

Aliases & Classifications for Spindle Cell Lipoma

About this section

Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 10 65


Classifications:



External Ids:

Disease Ontology10 DOID:10184
SNOMED-CT59 27313007, 404058008
NCIt42 C4254

Summaries for Spindle Cell Lipoma

About this section
Disease Ontology:10 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary: Spindle Cell Lipoma is related to adenoma and spindle cell liposarcoma. An important gene associated with Spindle Cell Lipoma is RB1 (Retinoblastoma 1), and among its related pathways are FOXM1 transcription factor network and TSH signaling pathway. Affiliated tissues include breast, tongue and skin, and related mouse phenotypes are cellular and behavior/neurological.

Wikipedia:68 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

About this section

Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 148)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma30.5ACTC1, VIM
2spindle cell liposarcoma30.2DES, MDM2, VIM
3lipoma11.3
4liposarcoma10.5
5solitary fibrous tumor10.5
6dermatofibrosarcoma protuberans10.4
7atypical lipomatous tumor10.4
8pleomorphic lipoma10.2
9pleomorphic adenoma10.2
10fibroma10.2
11myositis ossificans10.2
12cervicitis10.2
13fibrosarcoma10.2
14myositis10.2
15dysphagia10.2
16calcified aponeurotic fibroma10.2
17infantile free sialic acid storage disease10.2DES, VIM
18lymphatic neoplasm10.2DES, VIM
19esophageal disease10.2DES, VIM
20absence of fingerprints congenital milia10.2DES, VIM
21malignant teratocarcinosarcoma10.2DES, VIM
22epithelioid cell synovial sarcoma10.2DES, VIM
23uterine corpus serous adenocarcinoma10.2DES, VIM
24pancreatic colloid cystadenoma10.2DES, VIM
25vulvar syringoma10.2DES, VIM
26spigelian hernia-cryptorchidism syndrome10.2ACTC1, DES
27necrotizing fasciitis10.2ACTC1, DES
28familial syringomyelia10.2DES, VIM
29mesenchymoma10.2DES, VIM
30lymphangiomatosis10.2ACTC1, VIM
31gastric signet ring cell adenocarcinoma10.2ACTC1, VIM
32cervical verrucous carcinoma10.2DES, VIM
33uterine corpus adenocarcinofibroma10.2DES, VIM
34iodine antenatal infection10.2ACTC1, VIM
35pulmonary venous return anomaly10.2ACTC1, DES
36familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.1ACTC1, VIM
37paralytic poliomyelitis10.1ACTC1, VIM
38basal cell carcinoma 710.1ACTC1, VIM
39pediatric cns choriocarcinoma10.1ACTC1, VIM
40hand dermatosis10.1ACTC1, VIM
41kidney hemangiopericytoma10.1CDK4, VIM
42multilocular cystic renal cell carcinoma10.1ACTC1, VIM
43prostate adenoid cystic carcinoma10.1ACTC1, VIM
44dendritic cell thymoma10.1ACTC1, VIM
45graphite pneumoconiosis10.1ACTC1, VIM
46unilateral retinoblastoma10.1DES, RB1
47carney complex-trismus-pseudocamptodactyly syndrome10.1ACTC1, VIM
48non-proliferative fibrocystic change of the breast10.1ACTC1, DES
49rete ovarii adenoma10.1ACTC1, DES
50botulism10.1ACTC1, DES

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to spindle cell lipoma

Symptoms for Spindle Cell Lipoma

About this section

Drugs & Therapeutics for Spindle Cell Lipoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

About this section

Anatomical Context for Spindle Cell Lipoma

About this section

MalaCards organs/tissues related to Spindle Cell Lipoma:

33
Breast, Tongue, Skin, Bone

Animal Models for Spindle Cell Lipoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Spindle Cell Lipoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.8ACTC1, CDK4, MDM2, RB1, VIM
2MP:00053867.7CDK4, DES, MDM2, RB1, VIM
3MP:00053697.2ACTC1, CDK4, DES, MDM2, RB1, VIM
4MP:00053857.1ACTC1, CDK4, DES, MDM2, RB1, VIM
5MP:00107687.0ACTC1, CDK4, DES, MDM2, RB1, VIM

Publications for Spindle Cell Lipoma

About this section

Articles related to Spindle Cell Lipoma:

(show top 50)    (show all 150)
idTitleAuthorsYear
1
Rare occurrence of lip spindle cell lipoma. (25815220)
2015
2
"Low-Fat" Pseudoangiomatous Spindle Cell Lipoma: A Rare Variant With Loss of 13q14 Region. (25839893)
2015
3
"Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge. (26017060)
2015
4
Management of a Nasal Spindle Cell Lipoma: Diagnostic and Therapeutic Considerations. (26517318)
2015
5
Letter to the Editor: Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case. Response to Laliotis et al. (26017887)
2015
6
MR imaging features of spindle cell lipoma. (24240205)
2014
7
Spindle Cell Lipoma of the Orbit. (24819207)
2014
8
Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma:report of a case. (24166610)
2013
9
Transoral robotic surgery for huge spindle cell lipoma of the hypopharynx. (23851787)
2013
10
Spindle cell lipoma of the larynx. (23780614)
2013
11
Spindle cell lipoma: a rare tumor of the mediastinum. (23991327)
2013
12
Dysphagia caused by spindle cell lipoma of hypopharynx: presentation of clinical case and literature review. (23326743)
2012
13
Spindle cell lipoma: a case report and review of literature. (23132485)
2012
14
Spindle cell lipoma with collagen rosettes. (21645033)
2011
15
Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma. (20852591)
2011
16
An unusual and spectacular case of spindle cell lipoma of the posterior neck invading the spinal cervical canal and posterior cranial fossa. (21819187)
2011
17
Spindle cell lipoma of the orbit: a case report of an unusual orbital pathology. (20827617)
2010
18
Cutaneous CD34+ spindle cell neoplasms: Histopathologic features distinguish spindle cell lipoma, solitary fibrous tumor, and dermatofibrosarcoma protuberans. (20559119)
2010
19
Left supraclavicular spindle cell lipoma. (20508829)
2010
20
Spindle cell lipoma of the aortic valve: a rare cardiac finding. (19010061)
2010
21
Infantile fibrosarcoma successfully treated with chemotherapy, with occurrence of calcifying aponeurotic fibroma and pleomorphic/spindled celled lipoma at the site 12 years later. (19648795)
2009
22
Infiltrating intramuscular spindle cell lipoma of the face. (19187113)
2009
23
Spindle cell lipoma breast. (18603691)
2008
24
Spindle cell lipoma of the spermatic cord. (17956535)
2007
25
CD10 is expressed by mammary myofibroblastoma and spindle cell lipoma of soft tissue: an additional evidence of their histogenetic linking. (17497167)
2007
26
Spindle cell lipoma of the floor of the mouth. A case report. (16878055)
2006
27
Pathology quiz case 2. Spindle cell lipoma. (16490884)
2006
28
Synchronous ordinary lipoma and spindle-cell lipoma diagnosed by fine needle aspiration. (16680778)
2006
29
Spindle cell lipoma of the oral cavity. (16456321)
2006
30
Spindle cell lipoma showing biphasic pattern--a case report. (16075897)
2005
31
Spindle cell lipoma of the floor of the mouth: report of a case. (15917181)
2005
32
Spindle cell lipoma of the knee: a case report. (14767709)
2004
33
Dermal spindle cell lipoma of the posterior neck: CT and MR findings. (15018196)
2003
34
Imaging characteristics of spindle cell lipoma. (14573414)
2003
35
Intramuscular dendritic fibromyxolipoma: myxoid variant of spindle cell lipoma? (12675771)
2003
36
Spindle cell lipoma of the hypopharynx. (11453572)
2001
37
Spindle-cell lipoma of the cheek: a case report. (10964060)
2000
38
Pleomorphic lipoma with pseudopapillary structures: a pleomorphic counterpart of pseudoangiomatous spindle cell lipoma. (10792493)
2000
39
Fine-needle aspiration diagnosis of spindle-cell lipoma: a case report and review of the literature. (11074636)
2000
40
Myofibroblastoma of the breast: genetic link with spindle cell lipoma. (10878550)
2000
41
Spindle-cell lipoma of the preseptal eyelid. (9612807)
1998
42
Angiomyofibroblastomalike tumor of the male genital tract: analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma. (9422311)
1998
43
Spindle cell lipoma--a pseudoangiomatous variant. (8063285)
1994
44
Spindle cell lipoma within the larynx: a case report with correlated light and electron microscopy. (8321547)
1993
45
Spindle cell lipoma of the breast: a case report and literature review. (8261850)
1993
46
Spindle-cell lipoma: an unusual oral presentation. (2512544)
1989
47
Large intramuscular spindle-cell lipoma. With review of the literature. A case report. (3285867)
1988
48
Spindle cell lipoma. (6487132)
1984
49
Spindle-cell lipoma. A clinical, light- and electron-microscopical study. (7282993)
1981
50
Spindle cell lipoma (report of 2 cases and differential diagnosis). (205204)
1977

Variations for Spindle Cell Lipoma

About this section

Expression for genes affiliated with Spindle Cell Lipoma

About this section
Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for genes affiliated with Spindle Cell Lipoma

About this section

Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 28)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CDK4, RB1
29.5CDK4, RB1
3
Show member pathways
9.5DES, VIM
49.2MDM2, RB1
59.2MDM2, RB1
69.2MDM2, RB1
79.1CDK4, MDM2
89.1CDK4, MDM2
99.1CDK4, MDM2
109.0CDK4, RB1, VIM
118.9ACTC1, DES, VIM
12
Show member pathways
8.9ACTC1, DES, VIM
138.7MDM2, RB1, VIM
14
Show member pathways
8.7CDK4, MDM2, RB1
158.7CDK4, MDM2, RB1
16
Show member pathways
8.7CDK4, MDM2, RB1
178.7CDK4, MDM2, RB1
188.7CDK4, MDM2, RB1
198.7CDK4, MDM2, RB1
20
Show member pathways
8.7CDK4, MDM2, RB1
218.7CDK4, MDM2, RB1
228.7CDK4, MDM2, RB1
238.7CDK4, MDM2, RB1
24
Show member pathways
8.7CDK4, MDM2, RB1
25
Show member pathways
8.7CDK4, MDM2, RB1
26
Show member pathways
8.7CDK4, MDM2, RB1
27
Show member pathways
8.7CDK4, MDM2, RB1
288.2CDK4, MDM2, RB1, VIM

GO Terms for genes affiliated with Spindle Cell Lipoma

About this section

Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300498.9ACTC1, DES, VIM
2negative regulation of cell cycle arrestGO:00711578.8CDK4, MDM2

Molecular functions related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.4MDM2, VIM
2identical protein bindingGO:00428028.3DES, MDM2, RB1, VIM

Sources for Spindle Cell Lipoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet