MCID: SPN006
MIFTS: 35

Spindle Cell Lipoma malady

Category: Cancer diseases

Aliases & Classifications for Spindle Cell Lipoma

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Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:10184
SNOMED-CT62 27313007, 404058008
NCIt45 C4254

Summaries for Spindle Cell Lipoma

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Disease Ontology:11 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary: Spindle Cell Lipoma is related to pleomorphic lipoma and lipoma. An important gene associated with Spindle Cell Lipoma is DES (Desmin), and among its related pathways are Aurora B signaling and Human Thyroid Stimulating Hormone (TSH) signaling pathway. Affiliated tissues include breast, tongue and skin, and related mouse phenotypes are pigmentation and cardiovascular system.

Wikipedia:71 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

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Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 141)
idRelated DiseaseScoreTop Affiliating Genes
1pleomorphic lipoma11.3
2lipoma10.8
3oral erosive lichen10.2ACTC1, DES
4carbon monoxide-induced parkinsonism10.2ACTC1, DES
5vagina leiomyosarcoma10.2ACTC1, DES
6inflammatory linear verrucous epidermal nevus10.2DES, VIM
7lymphomatous thyroiditis10.2DES, VIM
8pustulosis palmaris et plantaris10.2ACTC1, DES
9marfanoid hypermobility syndrome10.2DES, VIM
10adult endodermal sinus tumor10.2DES, VIM
11biliary papillomatosis10.2DES, VIM
12tanycytic ependymoma10.2DES, VIM
13lymphomatoid papulosis10.2ACTC1, VIM
14chest wall parachordoma10.2ACTC1, VIM
15liver angiosarcoma10.2DES, VIM
16cavernous sinus meningioma10.2DES, VIM
17male reproductive system disease10.2DES, VIM
18isolated anterior cervical hypertrichosis10.2ACTC1, VIM
19petrous apex meningioma10.2DES, VIM
20tinea favosa10.2ACTC1, DES
21vulvar squamous papilloma10.2DES, VIM
22anal gland neoplasm10.2DES, VIM
23conjunctival cancer10.2ACTC1, VIM
24skin glomus tumor10.2DES, VIM
25testicular granulosa cell tumor10.1ACTC1, VIM
26congenital muscular dystrophy with hyperlaxity10.1DES, VIM
27lymphangiosarcoma10.1ACTC1, VIM
28hypogonadotropic hypogonadism-retinitis pigmentosa syndrome10.1ACTC1, VIM
29cauda equina intradural extramedullary astrocytoma10.1ACTC1, VIM
30gangliosidosis gm110.1ACTC1, DES
31extracutaneous mastocytoma10.1DES, RB1
32spindle cell rhabdomyosarcoma10.1ACTC1, DES
33jewett-marshall bladder cancer10.1DES, VIM
34growth retardation hydrocephaly lung hypoplasia10.1ACTC1, VIM
35ostertagiasis10.1ACTC1, DES
36desmoid tumor10.1ACTC1, VIM
37popliteal pterygium syndrome, bartsocas-papas type10.1ACTC1, VIM
38ossifying fibromyxoid tumor10.1CDK4, VIM
39sengers syndrome10.1DES, VIM
40c-p angle neurinoma10.1DES, VIM
41extranodal nasal nk/t cell lymphoma10.1CDK4, RB1
4213q12.3 microdeletion syndrome10.0ACTC1, DES, VIM
43rommen mueller sybert syndrome10.0CDK4, MDM2
44myoma10.0ACTC1, DES, VIM
45congenital myasthenic syndrome10.0ACTC1, DES, VIM
46spleen angiosarcoma10.0ACTC1, DES, VIM
47malignant dermis tumor10.0ACTC1, DES, VIM
48urethral cancer10.0ACTC1, DES, VIM
49biemond syndrome10.0ACTC1, DES, VIM
50intestinal obstruction10.0ACTC1, DES, VIM

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to spindle cell lipoma

Symptoms & Phenotypes for Spindle Cell Lipoma

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MGI Mouse Phenotypes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011868.5CDK4, MDM2, RB1
2MP:00053858.0ACTC1, CDK4, DES, MDM2, RB1, VIM
3MP:00053848.0ACTC1, CDK4, DES, MDM2, RB1, VIM
4MP:00053767.9ACTC1, CDK4, DES, MDM2, RB1, VIM
5MP:00107687.9ACTC1, CDK4, DES, MDM2, RB1, VIM
6MP:00053697.8ACTC1, CDK4, DES, MDM2, RB1, VIM

Drugs & Therapeutics for Spindle Cell Lipoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

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Anatomical Context for Spindle Cell Lipoma

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MalaCards organs/tissues related to Spindle Cell Lipoma:

36
Breast, Tongue, Skin, Bone

Publications for Spindle Cell Lipoma

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Articles related to Spindle Cell Lipoma:

(show top 50)    (show all 162)
idTitleAuthorsYear
1
Cytogenetic Analysis of a Pseudoangiomatous Pleomorphic/Spindle Cell Lipoma. (28476785)
2017
2
Cytohistological Features of Spindle Cell Lipoma- A Case Report with Differential Diagnosis. (28384874)
2017
3
Spindle Cell Lipoma in Dogs. (28494701)
2017
4
Pseudoangiomatous Spindle Cell Lipoma: a distinct subtype of spindle cell lipoma. (27982506)
2016
5
Dermal plexiform spindle cell lipoma. (27833986)
2016
6
S-100 protein expressing spindle cells in spindle cell lipoma: a diagnostic pitfall. (27444171)
2016
7
Pseudoangiomatous variant of spindle cell lipoma: Report of a rare case. (27510682)
2016
8
Low-Fat Plexiform Spindle Cell Lipoma With Prominent Myxoid Stroma: An Unusual Oral Presentation and Immunohistochemical Analysis. (28045832)
2016
9
Spindle Cell Lipoma in an End-Stage Renal Allograft: Case Report. (27932168)
2016
10
Spindle cell lipoma of the soft palate. (25878917)
2015
11
Acute dyspnea caused by a giant spindle cell lipoma of the larynx. (26438102)
2015
12
Oral Spindle Cell Lipoma in a Rare Location: A Differential Diagnosis. (26615969)
2015
13
Spindle cell lipoma with predominant nerve sheath tumor-like areas: A potential diagnostic pitfall on aspiration cytology. (26457887)
2015
14
Low-Fat" Pseudoangiomatous Spindle Cell Lipoma: A Rare Variant With Loss of 13q14 Region. (25839893)
2015
15
Spindle Cell Lipoma of the Neck: Review of the Literature and Case Report. (26893975)
2015
16
Spindle Cell Lipoma Occurring in the Buccal Mucosa: An Unusual Location of This Benign Lipomatous Neoplasm. (26491592)
2015
17
Management of a Nasal Spindle Cell Lipoma: Diagnostic and Therapeutic Considerations. (26517318)
2015
18
Spindle cell lipoma of the wrist, occurring in a distinctly rare location: a case report with review of literature. (26045856)
2015
19
Spindle cell lipoma of the tongue. (25682756)
2015
20
Rare occurrence of lip spindle cell lipoma. (25815220)
2015
21
Intramuscular spindle cell lipoma of the deltoid: a case report. (25880875)
2015
22
Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge. (26017060)
2015
23
Diagnostically challenging case of low-fat spindle cell lipoma. (26053070)
2015
24
Folliculosebaceous Cystic Hamartoma With Spindle Cell Lipoma-Like Stromal Features. (26588344)
2015
25
Letter to the Editor: Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case. Response to Laliotis et al. (26017887)
2015
26
Dendritic fibromyxolipoma: a variant of spindle cell lipoma with extensive myxoid change, with cytogenetic evidence. (25047505)
2014
27
Re: co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma. Report of a case. (25119179)
2014
28
A rare case of spindle cell lipoma of broad ligament presenting as a pelvic mass. (25422813)
2014
29
Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. (24659226)
2014
30
RE: "Fat-free" spindle cell lipoma in retropharynx. (24843246)
2014
31
Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature. (25319950)
2014
32
Spindle cell lipoma of the mandibular mucogingival junction: a case report of unusual oral neoplasm. (24556953)
2014
33
Spindle cell lipoma adherent to the digital nerve in the palm. (25414563)
2014
34
Spindle Cell Lipoma of the Orbit. (24819207)
2014
35
MR imaging features of spindle cell lipoma. (24240205)
2014
36
Spindle Cell Lipoma of the Conjunctiva. (24911538)
2014
37
Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case Ivan Chernev, Shane Mctighe, Dirk P. Stanley. (25372424)
2014
38
Imaging characteristics of spindle cell lipoma and its variants. (24554024)
2014
39
Myofibroblastoma of the female breast with admixed but distinct foci of spindle cell lipoma: a case report. (24459597)
2013
40
Transoral robotic surgery for huge spindle cell lipoma of the hypopharynx. (23851787)
2013
41
Spindle cell lipoma of the tongue: A case report of unusual occurrence. (23798855)
2013
42
Spindle cell lipoma: a rare tumor of the mediastinum. (23991327)
2013
43
Subungual spindle cell lipoma. (22171806)
2013
44
Spindle cell lipoma of the head and neck: CT and MR imaging findings. (23053001)
2013
45
Fine needle aspiration biopsy of intraparotid spindle cell lipoma: a case report. (22021087)
2013
46
Spindle cell lipoma. (23946512)
2013
47
Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma:report of a case. (24166610)
2013
48
Spindle cell lipoma of the larynx. (23780614)
2013
49
Spindle cell lipoma masquerading as lipomatous pleomorphic adenoma: A diagnostic dilemma on fine needle aspiration cytology. (23661944)
2013
50
Spindle cell lipoma: a case report and review of literature. (23132485)
2012

Variations for Spindle Cell Lipoma

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Expression for genes affiliated with Spindle Cell Lipoma

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Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for genes affiliated with Spindle Cell Lipoma

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Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5DES, VIM
29.3CDK4, RB1
39.3CDK4, RB1
4
Show member pathways
9.3CDK4, RB1
59.1CDK4, MDM2
69.1CDK4, MDM2
79.1ACTC1, DES, VIM
89.1ACTC1, DES, VIM
99.0MDM2, RB1
109.0MDM2, RB1
11
Show member pathways
8.9CDK4, DES, RB1
128.8CDK4, RB1, VIM
138.8CDK4, RB1, VIM
148.5MDM2, RB1, VIM
15
Show member pathways
8.5CDK4, MDM2, RB1
168.5CDK4, MDM2, RB1
17
Show member pathways
8.5CDK4, MDM2, RB1
18
Show member pathways
8.5CDK4, MDM2, RB1
19
Show member pathways
8.5CDK4, MDM2, RB1
208.5CDK4, MDM2, RB1
218.5CDK4, MDM2, RB1
22
Show member pathways
8.5CDK4, MDM2, RB1
23
Show member pathways
8.5CDK4, MDM2, RB1
248.5CDK4, MDM2, RB1
258.5CDK4, MDM2, RB1
26
Show member pathways
8.5CDK4, MDM2, RB1
278.5CDK4, MDM2, RB1
28
Show member pathways
8.5CDK4, MDM2, RB1
298.0CDK4, MDM2, RB1, VIM

GO Terms for genes affiliated with Spindle Cell Lipoma

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Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:004510910.3DES, VIM
2negative regulation of cell cycle arrestGO:00711579.8CDK4, MDM2
3negative regulation of neuron projection developmentGO:00109779.8MDM2, VIM
4positive regulation of cell cycleGO:00457879.8CDK4, MDM2
5muscle filament slidingGO:00300499.8ACTC1, DES, VIM
6positive regulation of gene expressionGO:00106289.4ACTC1, MDM2, VIM
7response to drugGO:00424939.3ACTC1, CDK4, MDM2
8viral processGO:00160328.5MDM2, RB1, VIM

Molecular functions related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1disordered domain specific bindingGO:00977189.7MDM2, RB1
2scaffold protein bindingGO:00971109.1MDM2, VIM
3identical protein bindingGO:00428028.6DES, MDM2, RB1, VIM

Sources for Spindle Cell Lipoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet