MCID: SPN006
MIFTS: 34

Spindle Cell Lipoma malady

Category: Cancer diseases

Aliases & Classifications for Spindle Cell Lipoma

About this section

Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:10184
SNOMED-CT62 27313007, 404058008
NCIt45 C4254

Summaries for Spindle Cell Lipoma

About this section
Disease Ontology:11 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary: Spindle Cell Lipoma is related to spindle cell liposarcoma and fibrosarcoma. An important gene associated with Spindle Cell Lipoma is DES (Desmin), and among its related pathways are Aurora B signaling and FOXM1 transcription factor network. Affiliated tissues include tongue, skin and bone, and related mouse phenotypes are pigmentation and cardiovascular system.

Wikipedia:71 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

About this section

Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 121)
idRelated DiseaseScoreTop Affiliating Genes
1spindle cell liposarcoma29.5CDK4, MDM2
2fibrosarcoma29.1CDK4, DES, MDM2
3pleomorphic lipoma11.3
4lipoma10.8
5xq12-q13.3 duplication syndrome10.4ACTC1, DES
6intravascular fasciitis10.4ACTC1, DES
7pura syndrome10.3ACTC1, DES
8harding ataxia10.3DES, VIM
9absence of fingerprints congenital milia10.3DES, VIM
10lymphocytic vasculitis10.3DES, VIM
11pancreatic delta cell neoplasm10.3DES, VIM
12anterograde amnesia10.3DES, VIM
13monophasic synovial sarcoma10.3DES, VIM
14lymphangiomatosis10.3ACTC1, VIM
15bartholin's gland benign neoplasm10.3DES, VIM
16myxoid liposarcoma of the ovary10.3ACTC1, VIM
17malignant adenofibroma10.3DES, VIM
18parovarian cyst10.3ACTC1, DES
19iridogoniodysgenesis and skeletal anomalies10.3ACTC1, VIM
20focal chorioretinitis10.3DES, VIM
21skin sarcoma10.3ACTC1, VIM
22vulvar alveolar soft part sarcoma10.2ACTC1, VIM
23eccrine papillary adenoma10.2ACTC1, VIM
24angora hair nevus10.2DES, VIM
25malignant peritoneal solitary fibrous tumor10.2ACTC1, VIM
26gangliocytoma10.2DES, VIM
27pineal parenchymal tumor of intermediate differenciation10.2ACTC1, VIM
28orbit rhabdomyosarcoma10.2ACTC1, DES
29ovarian cystadenocarcinoma10.2ACTC1, VIM
30vascular hemostatic disease10.2ACTC1, VIM
31intraocular retinoblastoma10.2DES, RB1
32fibrosing mediastinitis10.2DES, VIM
33longitudinal vaginal septum10.2ACTC1, DES
34paranasal sinus cancer, adult10.2ACTC1, VIM
35meige syndrome10.2ACTC1, DES
36adenofibroma10.2CDK4, VIM
37dens in dente and palatal invaginations10.2ACTC1, VIM
38polyomavirus allograft nephropathy10.1ACTC1, VIM
39glioma susceptibility 110.1ACTC1, VIM
40renal tubular acidosis, distal, autosomal recessive10.1DES, VIM
41advanced sleep-phase syndrome, familial, 210.0DES, VIM
42asrar facharzt haque syndrome10.0CDK4, RB1
43liposarcoma10.0
44chromosome 7p duplication10.0CDK4, MDM2
45epidural spinal canal angiolipoma10.0CDK4, MDM2
46osteogenesis imperfecta10.0CDK4, MDM2
47lymphangiosarcoma10.0ACTC1, DES, VIM
48chondroblastoma10.0ACTC1, DES, VIM
49pulmonary venoocclusive disease10.0ACTC1, DES, VIM
50mollaret meningitis10.0ACTC1, DES, VIM

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to spindle cell lipoma

Symptoms & Phenotypes for Spindle Cell Lipoma

About this section

MGI Mouse Phenotypes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011868.5CDK4, MDM2, RB1
2MP:00053858.0ACTC1, CDK4, DES, MDM2, RB1, VIM
3MP:00053847.9ACTC1, CDK4, DES, MDM2, RB1, VIM
4MP:00053767.9ACTC1, CDK4, DES, MDM2, RB1, VIM
5MP:00107687.9ACTC1, CDK4, DES, MDM2, RB1, VIM
6MP:00053697.8ACTC1, CDK4, DES, MDM2, RB1, VIM

Drugs & Therapeutics for Spindle Cell Lipoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

About this section

Anatomical Context for Spindle Cell Lipoma

About this section

MalaCards organs/tissues related to Spindle Cell Lipoma:

36
Tongue, Skin, Bone

Publications for Spindle Cell Lipoma

About this section

Articles related to Spindle Cell Lipoma:

(show top 50)    (show all 159)
idTitleAuthorsYear
1
Low-Fat Plexiform Spindle Cell Lipoma With Prominent Myxoid Stroma: An Unusual Oral Presentation and Immunohistochemical Analysis. (28045832)
2016
2
Dermal plexiform spindle cell lipoma. (27833986)
2016
3
Pseudoangiomatous variant of spindle cell lipoma: Report of a rare case. (27510682)
2016
4
Spindle Cell Lipoma in an End-Stage Renal Allograft: Case Report. (27932168)
2016
5
S-100 protein expressing spindle cells in spindle cell lipoma: a diagnostic pitfall. (27444171)
2016
6
Pseudoangiomatous Spindle Cell Lipoma: a distinct subtype of spindle cell lipoma. (27982506)
2016
7
Low-Fat" Pseudoangiomatous Spindle Cell Lipoma: A Rare Variant With Loss of 13q14 Region. (25839893)
2015
8
Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge. (26017060)
2015
9
Letter to the Editor: Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case. Response to Laliotis et al. (26017887)
2015
10
Spindle cell lipoma with predominant nerve sheath tumor-like areas: A potential diagnostic pitfall on aspiration cytology. (26457887)
2015
11
Intramuscular spindle cell lipoma of the deltoid: a case report. (25880875)
2015
12
Spindle cell lipoma of the wrist, occurring in a distinctly rare location: a case report with review of literature. (26045856)
2015
13
Diagnostically challenging case of low-fat spindle cell lipoma. (26053070)
2015
14
Spindle cell lipoma of the soft palate. (25878917)
2015
15
Folliculosebaceous Cystic Hamartoma With Spindle Cell Lipoma-Like Stromal Features. (26588344)
2015
16
Oral Spindle Cell Lipoma in a Rare Location: A Differential Diagnosis. (26615969)
2015
17
Spindle Cell Lipoma Occurring in the Buccal Mucosa: An Unusual Location of This Benign Lipomatous Neoplasm. (26491592)
2015
18
Spindle Cell Lipoma of the Neck: Review of the Literature and Case Report. (26893975)
2015
19
Rare occurrence of lip spindle cell lipoma. (25815220)
2015
20
Management of a Nasal Spindle Cell Lipoma: Diagnostic and Therapeutic Considerations. (26517318)
2015
21
Acute dyspnea caused by a giant spindle cell lipoma of the larynx. (26438102)
2015
22
Spindle cell lipoma of the tongue. (25682756)
2015
23
MR imaging features of spindle cell lipoma. (24240205)
2014
24
Spindle Cell Lipoma of the Orbit. (24819207)
2014
25
RE: "Fat-free" spindle cell lipoma in retropharynx. (24843246)
2014
26
Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case Ivan Chernev, Shane Mctighe, Dirk P. Stanley. (25372424)
2014
27
Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature. (25319950)
2014
28
Spindle cell lipoma of the mandibular mucogingival junction: a case report of unusual oral neoplasm. (24556953)
2014
29
Spindle cell lipoma adherent to the digital nerve in the palm. (25414563)
2014
30
Dendritic fibromyxolipoma: a variant of spindle cell lipoma with extensive myxoid change, with cytogenetic evidence. (25047505)
2014
31
Re: co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma. Report of a case. (25119179)
2014
32
Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. (24659226)
2014
33
Imaging characteristics of spindle cell lipoma and its variants. (24554024)
2014
34
A rare case of spindle cell lipoma of broad ligament presenting as a pelvic mass. (25422813)
2014
35
Spindle Cell Lipoma of the Conjunctiva. (24911538)
2014
36
Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma:report of a case. (24166610)
2013
37
Spindle cell lipoma: a rare tumor of the mediastinum. (23991327)
2013
38
Myofibroblastoma of the female breast with admixed but distinct foci of spindle cell lipoma: a case report. (24459597)
2013
39
Subungual spindle cell lipoma. (22171806)
2013
40
Spindle cell lipoma masquerading as lipomatous pleomorphic adenoma: A diagnostic dilemma on fine needle aspiration cytology. (23661944)
2013
41
Spindle cell lipoma of the head and neck: CT and MR imaging findings. (23053001)
2013
42
Spindle cell lipoma of the tongue: A case report of unusual occurrence. (23798855)
2013
43
Transoral robotic surgery for huge spindle cell lipoma of the hypopharynx. (23851787)
2013
44
Spindle cell lipoma of the larynx. (23780614)
2013
45
Spindle cell lipoma. (23946512)
2013
46
Fine needle aspiration biopsy of intraparotid spindle cell lipoma: a case report. (22021087)
2013
47
Dysphagia caused by spindle cell lipoma of hypopharynx: presentation of clinical case and literature review. (23326743)
2012
48
A rare case of spindle cell lipoma of nose. (23741588)
2012
49
Solitary fibrous tumor: is there a molecular relationship with cellular angiofibroma, spindle cell lipoma, and mammary-type myofibroblastoma? (22586056)
2012
50
Spindle cell lipoma: a case report and review of literature. (23132485)
2012

Variations for Spindle Cell Lipoma

About this section

Expression for genes affiliated with Spindle Cell Lipoma

About this section
Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for genes affiliated with Spindle Cell Lipoma

About this section

Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 28)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5DES, VIM
29.3CDK4, RB1
3
Show member pathways
9.3CDK4, RB1
49.3CDK4, RB1
59.1CDK4, MDM2
69.1CDK4, MDM2
79.1ACTC1, DES, VIM
89.1ACTC1, DES, VIM
99.0MDM2, RB1
109.0MDM2, RB1
118.8CDK4, RB1, VIM
128.8CDK4, RB1, VIM
138.5MDM2, RB1, VIM
14
Show member pathways
8.5CDK4, MDM2, RB1
158.5CDK4, MDM2, RB1
16
Show member pathways
8.5CDK4, MDM2, RB1
17
Show member pathways
8.5CDK4, MDM2, RB1
18
Show member pathways
8.5CDK4, MDM2, RB1
19
Show member pathways
8.5CDK4, MDM2, RB1
208.5CDK4, MDM2, RB1
218.5CDK4, MDM2, RB1
228.5CDK4, MDM2, RB1
238.5CDK4, MDM2, RB1
24
Show member pathways
8.5CDK4, MDM2, RB1
258.5CDK4, MDM2, RB1
26
Show member pathways
8.5CDK4, MDM2, RB1
278.0CDK4, MDM2, RB1, VIM
28
Show member pathways
7.6CDK4, DES, MDM2, RB1, VIM

GO Terms for genes affiliated with Spindle Cell Lipoma

About this section

Cellular components related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.5DES, VIM

Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:004510910.3DES, VIM
2negative regulation of cell cycle arrestGO:00711579.8CDK4, MDM2
3negative regulation of neuron projection developmentGO:00109779.8MDM2, VIM
4positive regulation of cell cycleGO:00457879.8CDK4, MDM2
5muscle filament slidingGO:00300499.8ACTC1, DES, VIM
6positive regulation of gene expressionGO:00106289.4ACTC1, MDM2, VIM
7response to drugGO:00424939.3ACTC1, CDK4, MDM2
8viral processGO:00160328.5MDM2, RB1, VIM

Molecular functions related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.1MDM2, VIM
2identical protein bindingGO:00428028.6DES, MDM2, RB1, VIM

Sources for Spindle Cell Lipoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet