MCID: SPN006
MIFTS: 36

Spindle Cell Lipoma malady

Category: Cancer diseases

Aliases & Classifications for Spindle Cell Lipoma

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Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:10184
SNOMED-CT59 27313007, 404058008
NCIt42 C4254
UMLS65 C0334474

Summaries for Spindle Cell Lipoma

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Disease Ontology:10 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary: Spindle Cell Lipoma is related to melanoma and pleomorphic lipoma. An important gene associated with Spindle Cell Lipoma is RB1 (Retinoblastoma 1), and among its related pathways are TSH signaling pathway and FOXM1 transcription factor network. Affiliated tissues include bone, breast and heart, and related mouse phenotypes are pigmentation and cellular.

Wikipedia:68 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

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Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 192)
idRelated DiseaseScoreTop Affiliating Genes
1melanoma28.6ACTC1, CDK4, DES, MDM2, VIM
2pleomorphic lipoma10.5
3lung cancer10.3
4gingival hypertrophy10.2DES, VIM
5malignant teratocarcinosarcoma10.2DES, VIM
6spindle cell variant squamous cell breast carcinoma10.2DES, VIM
7prostate cancer10.2
8breast cancer10.2
9arthritis10.2
10cataract10.2
11gastric cancer10.2
12hepatitis10.2
13leukemia10.2
14pseudotumor cerebri10.2
15prostatitis10.2
16cervicitis10.2
17gallbladder cancer10.2
18adenoma10.2
19endotheliitis10.2
20vulvar angiokeratoma10.2DES, VIM
21uterine corpus adenocarcinofibroma10.2DES, VIM
22pulmonary venous return anomaly10.1ACTC1, DES
23benign deep fibrous histiocytoma10.1ACTC1, DES
24thymus lipoma10.1ACTC1, DES
2546xy sex reversal 510.1DES, VIM
26proliferative fasciitis10.1ACTC1, DES
27absence of fingerprints congenital milia10.1ACTC1, VIM
28renal tubular acidosis, distal, autosomal recessive10.1DES, VIM
29familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.1ACTC1, VIM
30ovarian mucinous cystadenocarcinoma10.1ACTC1, VIM
31colorectal cancer10.1
32parathyroid carcinoma10.1
33ehlers-danlos syndrome, type iv10.1
34obesity10.1
35hepatitis c virus10.1
36alzheimer disease10.1
37psoriatic arthritis10.1
38riboflavin deficiency10.1
39glycerol kinase deficiency10.1
40incontinentia pigmenti10.1
41alopecia10.1
42intermittent claudication10.1
43keloids10.1
44male infertility10.1
45sinusitis10.1
46adenoiditis10.1
47small cell carcinoma10.1
48lymphoma10.1
49autotopagnosia10.1
50simultanagnosia10.1

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to spindle cell lipoma

Symptoms for Spindle Cell Lipoma

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Drugs & Therapeutics for Spindle Cell Lipoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

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Anatomical Context for Spindle Cell Lipoma

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MalaCards organs/tissues related to Spindle Cell Lipoma:

33
Bone, Breast, Heart, Liver, Kidney, T cells, Neutrophil

Animal Models for Spindle Cell Lipoma or affiliated genes

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MGI Mouse Phenotypes related to Spindle Cell Lipoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.0CDK4, MDM2, RB1
2MP:00053847.3ACTC1, CDK4, DES, MDM2, RB1, VIM
3MP:00053767.1ACTC1, CDK4, DES, MDM2, RB1, VIM
4MP:00053857.1ACTC1, CDK4, DES, MDM2, RB1, VIM
5MP:00053697.0ACTC1, CDK4, DES, MDM2, RB1, VIM
6MP:00107686.8ACTC1, CDK4, DES, MDM2, RB1, VIM

Publications for Spindle Cell Lipoma

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Articles related to Spindle Cell Lipoma:

(show top 50)    (show all 150)
idTitleAuthorsYear
1
Superoxide-hydrogen peroxide imbalance interferes with colorectal cancer cells viability, proliferation and oxaliplatin response. (26674755)
2016
2
Bone Scintigraphy in a Patient With Giant Malignant Solitary Fibrous Tumor of the Pleura. (26914570)
2016
3
Toxic shock syndrome due to methicillin-resistant Staphylococcus aureus infection after a pediatric scald burn. (26803714)
2015
4
Pallister-Killian syndrome. (25425112)
2014
5
Differential Evolutionary Fate of an Ancestral Primate Endogenous Retrovirus Envelope Gene, the EnvV Syncytin, Captured for a Function in Placentation. (23555306)
2013
6
Dyskinesia associated with hyperglycemia and basal ganglia hyperintensity: report of a rare diabetic complication. (23154926)
2013
7
Neurofibromatosis 1 and breast cancer: be alert. (23089412)
2012
8
Efficacy of miltefosine for topical treatment of Acanthamoeba keratitis in Syrian hamsters. (21748351)
2012
9
Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. (21810495)
2011
10
Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease. (21499257)
2011
11
Single incision laparoscopic splenectomy in a 5-year-old with hereditary spherocytosis. (20932387)
2010
12
Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer. (20204278)
2010
13
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. (19727076)
2009
14
Urinary fatty acid-binding protein 1: an early predictive biomarker of kidney injury. (19019918)
2009
15
Aberrant underexpression of CD81 in precursor B-cell acute lymphoblastic leukemia: utility in detection of minimal residual disease by flow cytometry. (19846809)
2009
16
Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report. (20184701)
2009
17
Urinary osteocalcin and other markers of bone metabolism: the effect of risedronate therapy. (18609099)
2008
18
Regulatory T-cell expansion and function do not account for the impaired alloreactivity of ex vivo-expanded T cells. (18445006)
2008
19
Functional cortical effects of novel allelic variants of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) in humans. (17874349)
2007
20
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
21
A discoidin domain receptor 1/SHP-2 signaling complex inhibits alpha2beta1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration. (16611743)
2006
22
Structure-activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels. (16309909)
2006
23
The P2 receptors and congenital platelet function defects. (15852220)
2005
24
An unusual presentation of tropical pyomyositis. (16114167)
2005
25
Secretion of proinflammatory cytokines and chemokines during amphotericin B exposure is mediated by coactivation of toll-like receptors 1 and 2. (15793154)
2005
26
Behavioral and emotional adjustment, family functioning, academic performance, and social relationships in children with selective mutism. (15482497)
2004
27
Implication of inflammation-related cytokines in the natural history of liver cirrhosis. (15482340)
2004
28
Genomic organization and evolution of the NF1 microdeletion region. (15233998)
2004
29
Pneumolabyrinth: an unusual finding in a temporal bone fracture. (12697360)
2003
30
Serum alpha-glutathione S-transferase as a sensitive marker of hepatocellular damage in patients with cystic fibrosis. (12790769)
2003
31
Sequential combination of thalidomide and erythropoietin determines transfusion independence and disease control in idiopathic myelofibrosis previously insensitive to both drugs used as single agents. (12886259)
2003
32
Acid-sensitive ion channels in gastrointestinal function. (14644014)
2003
33
Functional expression of the chemokine receptor CCR5 on virus epitope-specific memory and effector CD8+ T cells. (11859109)
2002
34
Role of calpain in human sperm activated by progesterone for fertilization. (11517938)
2001
35
Role of haemodialysis and hepatitis c virus infection in spontaneous and induced cytokine production of patients with chronic renal disease. (10930306)
2000
36
Induction of the heme oxygenase-1 gene by metalloporphyrins. (10933875)
2000
37
Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo. (10074452)
1999
38
Breast cancer and benign breast disease patients evaluated in relation to oxidative stress. (9925281)
1998
39
Apoptotic cell death upon contact of CD4+ T lymphocytes with HIV glycoprotein-expressing cells is mediated by caspases but bypasses CD95 (Fas/Apo-1) and TNF receptor 1. (9548463)
1997
40
Selective absence of cone outer segment beta 3-transducin immunoreactivity in hereditary cone degeneration (cd). (8943701)
1996
41
Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome. (8944018)
1996
42
Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes. (8627511)
1996
43
The cell adhesion molecule, VCAM-1, is selectively elevated in serum in pre-eclampsia: does this indicate the mechanism of leucocyte activation? (7538783)
1995
44
Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2-A resolution. (7537084)
1994
45
Molecular pathology of inherited erythrocyte membrane disorders: hereditary spherocytosis and elliptocytosis. (1356891)
1992
46
Gonadal dysgenesis reveals sexual dimorphism in the embryonic germline of Drosophila. (1657701)
1991
47
Different tissue distribution and hormonal regulation of messenger RNAs encoding rat insulin-like growth factor-binding proteins-1 and -2. (1691819)
1990
48
Distribution of meningococcal meningitis in England and Wales 1982-86. (2875294)
1986
49
Transient acantholytic dermatosis (Grover disease). (197142)
1977
50
Oral therapy of adrenal cortical hypofunction; use of combined fluorocortisone acetate and hydrocortisone. (13271094)
1955

Variations for Spindle Cell Lipoma

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Expression for genes affiliated with Spindle Cell Lipoma

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Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for genes affiliated with Spindle Cell Lipoma

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Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 26)
idSuper pathwaysScoreTop Affiliating Genes
19.5CDK4, RB1
29.5CDK4, RB1
3
Show member pathways
9.5DES, VIM
49.2MDM2, RB1
59.2MDM2, RB1
69.2MDM2, RB1
79.1CDK4, MDM2
89.1CDK4, MDM2
99.0CDK4, RB1, VIM
108.9ACTC1, DES, VIM
118.7MDM2, RB1, VIM
128.7CDK4, MDM2, RB1
13
Show member pathways
8.7CDK4, MDM2, RB1
14
Show member pathways
8.7CDK4, MDM2, RB1
15
Show member pathways
8.7CDK4, MDM2, RB1
168.7CDK4, MDM2, RB1
17
Show member pathways
8.7CDK4, MDM2, RB1
18
Show member pathways
8.7CDK4, MDM2, RB1
198.7CDK4, MDM2, RB1
208.7CDK4, MDM2, RB1
21
Show member pathways
8.7CDK4, MDM2, RB1
228.7CDK4, MDM2, RB1
238.7CDK4, MDM2, RB1
24
Show member pathways
8.7CDK4, MDM2, RB1
25
Show member pathways
8.7CDK4, MDM2, RB1
268.7CDK4, MDM2, RB1

GO Terms for genes affiliated with Spindle Cell Lipoma

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Cellular components related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.5DES, VIM

Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of cell cycleGO:00517269.5CDK4, RB1
2muscle filament slidingGO:00300499.5ACTC1, VIM
3response to toxic substanceGO:00096368.8CDK4, MDM2

Sources for Spindle Cell Lipoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet