MCID: SPN006
MIFTS: 36

Spindle Cell Lipoma malady

Category: Cancer diseases

Aliases & Classifications for Spindle Cell Lipoma

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Aliases & Descriptions for Spindle Cell Lipoma:

Name: Spindle Cell Lipoma 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:10184
SNOMED-CT60 27313007, 404058008
NCIt43 C4254

Summaries for Spindle Cell Lipoma

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Disease Ontology:11 A lipoma that is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.

MalaCards based summary: Spindle Cell Lipoma is related to spindle cell liposarcoma and fibrosarcoma. An important gene associated with Spindle Cell Lipoma is DES (Desmin), and among its related pathways are Aurora B signaling and FOXM1 transcription factor network. Affiliated tissues include breast, tongue and skin, and related mouse phenotypes are pigmentation and cellular.

Wikipedia:69 Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the... more...

Related Diseases for Spindle Cell Lipoma

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Diseases related to Spindle Cell Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 122)
idRelated DiseaseScoreTop Affiliating Genes
1spindle cell liposarcoma29.7CDK4, MDM2
2fibrosarcoma29.2CDK4, DES, MDM2
3lipoma10.9
4pleomorphic lipoma10.6
5xq12-q13.3 duplication syndrome10.5ACTC1, DES
6intravascular fasciitis10.4ACTC1, DES
7pura syndrome10.4ACTC1, DES
8harding ataxia10.4DES, VIM
9absence of fingerprints congenital milia10.4DES, VIM
10lymphocytic vasculitis10.4DES, VIM
11pancreatic delta cell neoplasm10.4DES, VIM
12anterograde amnesia10.4DES, VIM
13monophasic synovial sarcoma10.4DES, VIM
14lymphangiomatosis10.4ACTC1, VIM
15bartholin's gland benign neoplasm10.4DES, VIM
16malignant adenofibroma10.4DES, VIM
17myxoid liposarcoma of the ovary10.4ACTC1, VIM
18parovarian cyst10.4ACTC1, DES
19iridogoniodysgenesis and skeletal anomalies10.3ACTC1, VIM
20focal chorioretinitis10.3DES, VIM
21skin sarcoma10.3ACTC1, VIM
22vulvar alveolar soft part sarcoma10.3ACTC1, VIM
23angora hair nevus10.3DES, VIM
24eccrine papillary adenoma10.3ACTC1, VIM
25gangliocytoma10.3DES, VIM
26malignant peritoneal solitary fibrous tumor10.3ACTC1, VIM
27pineal parenchymal tumor of intermediate differenciation10.3ACTC1, VIM
28ovarian cystadenocarcinoma10.3ACTC1, VIM
29orbit rhabdomyosarcoma10.3ACTC1, DES
30skene gland carcinoma10.3DES, VIM
31vascular hemostatic disease10.3ACTC1, VIM
32intraocular retinoblastoma10.3DES, RB1
33paranasal sinus cancer, adult10.2ACTC1, VIM
34fibrosing mediastinitis10.2DES, VIM
35longitudinal vaginal septum10.2ACTC1, DES
36adenofibroma10.2CDK4, VIM
37meige syndrome10.2ACTC1, DES
38dens in dente and palatal invaginations10.2ACTC1, VIM
39polyomavirus allograft nephropathy10.2ACTC1, VIM
40glioma susceptibility 110.2ACTC1, VIM
41renal tubular acidosis, distal, autosomal recessive10.2DES, VIM
42liposarcoma10.1
43advanced sleep-phase syndrome, familial, 210.1DES, VIM
44asrar facharzt haque syndrome10.1CDK4, RB1
45dermatofibrosarcoma protuberans10.0
46atypical lipomatous tumor10.0
47chromosome 7p duplication10.0CDK4, MDM2
48epidural spinal canal angiolipoma10.0CDK4, MDM2
49osteogenesis imperfecta10.0CDK4, MDM2
50lymphangiosarcoma10.0ACTC1, DES, VIM

Graphical network of the top 20 diseases related to Spindle Cell Lipoma:



Diseases related to spindle cell lipoma

Symptoms for Spindle Cell Lipoma

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Drugs & Therapeutics for Spindle Cell Lipoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Spindle Cell Lipoma

Genetic Tests for Spindle Cell Lipoma

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Anatomical Context for Spindle Cell Lipoma

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MalaCards organs/tissues related to Spindle Cell Lipoma:

34
Breast, Tongue, Skin, Bone

Animal Models for Spindle Cell Lipoma or affiliated genes

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MGI Mouse Phenotypes related to Spindle Cell Lipoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011868.9CDK4, MDM2, RB1
2MP:00053847.4ACTC1, CDK4, DES, MDM2, RB1, VIM
3MP:00053697.3ACTC1, CDK4, DES, MDM2, RB1, VIM
4MP:00053767.1ACTC1, CDK4, DES, MDM2, RB1, VIM
5MP:00107687.0ACTC1, CDK4, DES, MDM2, RB1, VIM
6MP:00053856.8ACTC1, CDK4, DES, MDM2, RB1, VIM

Publications for Spindle Cell Lipoma

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Articles related to Spindle Cell Lipoma:

(show top 50)    (show all 155)
idTitleAuthorsYear
1
Pseudoangiomatous variant of spindle cell lipoma: Report of a rare case. (27510682)
2016
2
"Low-Fat" Pseudoangiomatous Spindle Cell Lipoma: A Rare Variant With Loss of 13q14 Region. (25839893)
2015
3
"Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge. (26017060)
2015
4
Letter to the Editor: Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case. Response to Laliotis et al. (26017887)
2015
5
Spindle cell lipoma with predominant nerve sheath tumor-like areas: A potential diagnostic pitfall on aspiration cytology. (26457887)
2015
6
Intramuscular spindle cell lipoma of the deltoid: a case report. (25880875)
2015
7
Spindle cell lipoma of the wrist, occurring in a distinctly rare location: a case report with review of literature. (26045856)
2015
8
MR imaging features of spindle cell lipoma. (24240205)
2014
9
Spindle Cell Lipoma of the Orbit. (24819207)
2014
10
RE: "Fat-free" spindle cell lipoma in retropharynx. (24843246)
2014
11
Re: Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma: Report of a case Ivan Chernev, Shane Mctighe, Dirk P. Stanley. (25372424)
2014
12
Co-existence of intramuscular spindle cell lipoma with an intramuscular ordinary lipoma:report of a case. (24166610)
2013
13
Spindle cell lipoma: a rare tumor of the mediastinum. (23991327)
2013
14
Myofibroblastoma of the female breast with admixed but distinct foci of spindle cell lipoma: a case report. (24459597)
2013
15
Dysphagia caused by spindle cell lipoma of hypopharynx: presentation of clinical case and literature review. (23326743)
2012
16
A rare case of spindle cell lipoma of nose. (23741588)
2012
17
Maxillary intraosseous spindle cell lipoma. (21497000)
2011
18
Spindle cell lipoma of the orbit: a case report of an unusual orbital pathology. (20827617)
2010
19
Left supraclavicular spindle cell lipoma. (20508829)
2010
20
Infantile fibrosarcoma successfully treated with chemotherapy, with occurrence of calcifying aponeurotic fibroma and pleomorphic/spindled celled lipoma at the site 12 years later. (19648795)
2009
21
Spindle-cell lipoma. (19623524)
2009
22
Spindle cell lipoma of the vestibule of the nose. (18656742)
2008
23
Spindle cell lipoma of the spermatic cord. (17956535)
2007
24
CD10 is expressed by mammary myofibroblastoma and spindle cell lipoma of soft tissue: an additional evidence of their histogenetic linking. (17497167)
2007
25
Giant spindle cell lipoma of the posterior neck. (17903161)
2007
26
Acute stridor caused by a previously asymptomatic large oropharyngeal spindle cell lipoma. (17433592)
2007
27
Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report. (17854668)
2007
28
Synchronous ordinary lipoma and spindle-cell lipoma diagnosed by fine needle aspiration. (16680778)
2006
29
Spindle cell lipoma of the oral cavity. (16456321)
2006
30
Spindle cell lipoma in the posterior third of the tongue. (17380840)
2006
31
Spindle cell lipoma showing biphasic pattern--a case report. (16075897)
2005
32
Spindle cell lipoma of the spermatic cord. (15138540)
2004
33
Imaging characteristics of spindle cell lipoma. (14573414)
2003
34
Spindle cell lipoma of the alveolar mucosa: a case report. (11862206)
2002
35
Spindle cell lipoma of the hypopharynx. (11453572)
2001
36
Intramuscular spindle cell lipoma: Case report and review of the literature. (11350614)
2001
37
Mammary-type myofibroblastoma of soft tissue: a tumor closely related to spindle cell lipoma. (11474286)
2001
38
Spindle cell lipoma with extramedullary haematopoiesis. (11493343)
2001
39
Spindle-cell lipoma of the cheek: a case report. (10964060)
2000
40
Pleomorphic lipoma with pseudopapillary structures: a pleomorphic counterpart of pseudoangiomatous spindle cell lipoma. (10792493)
2000
41
Fine-needle aspiration diagnosis of spindle-cell lipoma: a case report and review of the literature. (11074636)
2000
42
Spindle cell lipoma of the scalp: a case report and review. (9935099)
1999
43
Spindle-cell lipoma of the preseptal eyelid. (9612807)
1998
44
Spindle cell lipoma--a pseudoangiomatous variant. (8063285)
1994
45
Spindle cell lipoma of the breast: a case report and literature review. (8261850)
1993
46
Spindle-cell lipoma: an unusual oral presentation. (2512544)
1989
47
Large intramuscular spindle-cell lipoma. With review of the literature. A case report. (3285867)
1988
48
Spindle cell lipoma: a clinicopathological study with some original observations. (3623439)
1987
49
Spindle cell lipoma. (6487132)
1984
50
Spindle cell lipoma (report of 2 cases and differential diagnosis). (205204)
1977

Variations for Spindle Cell Lipoma

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Expression for genes affiliated with Spindle Cell Lipoma

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Search GEO for disease gene expression data for Spindle Cell Lipoma.

Pathways for genes affiliated with Spindle Cell Lipoma

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Pathways related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 30)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5DES, VIM
29.3CDK4, RB1
3
Show member pathways
9.3CDK4, RB1
49.3CDK4, RB1
59.1CDK4, MDM2
69.1CDK4, MDM2
79.1ACTC1, DES, VIM
89.1ACTC1, DES, VIM
99.0MDM2, RB1
109.0MDM2, RB1
118.8CDK4, RB1, VIM
128.8CDK4, RB1, VIM
138.5MDM2, RB1, VIM
14
Show member pathways
8.5CDK4, MDM2, RB1
158.5CDK4, MDM2, RB1
16
Show member pathways
8.5CDK4, MDM2, RB1
17
Show member pathways
8.5CDK4, MDM2, RB1
188.5CDK4, MDM2, RB1
19
Show member pathways
8.5CDK4, MDM2, RB1
20
Show member pathways
8.5CDK4, MDM2, RB1
218.5CDK4, MDM2, RB1
228.5CDK4, MDM2, RB1
238.5CDK4, MDM2, RB1
248.5CDK4, MDM2, RB1
258.5CDK4, MDM2, RB1
26
Show member pathways
8.5CDK4, MDM2, RB1
27
Show member pathways
8.5CDK4, MDM2, RB1
28
Show member pathways
8.5CDK4, MDM2, RB1
298.0CDK4, MDM2, RB1, VIM
30
Show member pathways
7.6CDK4, DES, MDM2, RB1, VIM

GO Terms for genes affiliated with Spindle Cell Lipoma

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Cellular components related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.5DES, VIM

Biological processes related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:00451099.8DES, VIM
2negative regulation of cell cycle arrestGO:00711579.6CDK4, MDM2
3positive regulation of cell cycleGO:00457879.6CDK4, MDM2
4muscle filament slidingGO:00300499.3ACTC1, DES, VIM
5negative regulation of neuron projection developmentGO:00109779.0MDM2, VIM
6positive regulation of gene expressionGO:00106288.8ACTC1, MDM2, VIM
7viral processGO:00160328.8MDM2, RB1, VIM
8response to drugGO:00424938.7ACTC1, CDK4, MDM2

Molecular functions related to Spindle Cell Lipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.4MDM2, VIM
2identical protein bindingGO:00428028.1DES, MDM2, RB1, VIM

Sources for Spindle Cell Lipoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet