MCID: SPN009
MIFTS: 24

Spindle Cell Rhabdomyosarcoma malady

Aliases & Classifications for Spindle Cell Rhabdomyosarcoma

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Spindle Cell Rhabdomyosarcoma, Aliases & Descriptions:

Name: Spindle Cell Rhabdomyosarcoma 9 60


External Ids:

Disease Ontology9 DOID:3260
NCIt38 C6519

Summaries for Spindle Cell Rhabdomyosarcoma

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Wikipedia:63 Spindle cell rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma first described by Cavazzana,... more...

MalaCards based summary: Spindle Cell Rhabdomyosarcoma is related to rhabdomyosarcoma and embryonal rhabdomyosarcoma. An important gene associated with Spindle Cell Rhabdomyosarcoma is DES (desmin), and among its related pathways are L1CAM interactions and Immune response Function of MEF2 in T lymphocytes. The compounds dihydrotestosterone and triiodothyronine have been mentioned in the context of this disorder. Affiliated tissues include prostate and tongue.

Related Diseases for Spindle Cell Rhabdomyosarcoma

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Graphical network of diseases related to Spindle Cell Rhabdomyosarcoma:



Diseases related to spindle cell rhabdomyosarcoma

Symptoms for Spindle Cell Rhabdomyosarcoma

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Drugs & Therapeutics for Spindle Cell Rhabdomyosarcoma

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Drug clinical trials:

Search ClinicalTrials for Spindle Cell Rhabdomyosarcoma

Search NIH Clinical Center for Spindle Cell Rhabdomyosarcoma

Genetic Tests for Spindle Cell Rhabdomyosarcoma

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Anatomical Context for Spindle Cell Rhabdomyosarcoma

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MalaCards organs/tissues related to Spindle Cell Rhabdomyosarcoma:

31
Prostate, Tongue

Animal Models for Spindle Cell Rhabdomyosarcoma or affiliated genes

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Publications for Spindle Cell Rhabdomyosarcoma

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Articles related to Spindle Cell Rhabdomyosarcoma:

(show all 26)
idTitleAuthorsYear
1
Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma. (24272621)
2014
2
An adult spindle cell rhabdomyosarcoma in the head and neck region with long-term survival: a case report. (24946859)
2014
3
Spindle cell rhabdomyosarcoma in the hypopharynx of an adult. (25197406)
2014
4
Spindle cell rhabdomyosarcoma of the retroperitoneum: an unusual case developed in a pregnant woman but obscured by pregnancy. (25197361)
2014
5
Spindle cell rhabdomyosarcoma of the neck with t(6;8) translocation: report of a case and literature review. (23113671)
2013
6
Spindle cell rhabdomyosarcoma of the prostate. (23320845)
2013
7
Spindle cell rhabdomyosarcoma displaying CD34 positivity: a potential diagnostic pitfall; report of two pediatric cases. (24022313)
2013
8
Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis. (23899074)
2013
9
Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma. (23463663)
2013
10
Exfoliative cytologic findings of maxillary sinus spindle cell rhabdomyosarcoma. (20518428)
2010
11
Aggressive spindle cell rhabdomyosarcoma in an 11-month-old boxer dog. (20460837)
2010
12
Sclerosing spindle cell rhabdomyosarcoma in an adult: report of a new case and review of the literature. (19017660)
2010
13
Radiation-induced mandibular adult spindle cell rhabdomyosarcoma. (18023143)
2008
14
Clinicopathologic analysis of spindle cell rhabdomyosarcoma: report of 8 cases]. (18646700)
2008
15
Kit expression in spindle cell rhabdomyosarcoma can possibly create a different approach for its tumorigenesis and therapy. (16860492)
2006
16
Spindle cell rhabdomyosarcoma in adults: clinicopathological and immunohistochemical analysis of seven new cases. (17013628)
2006
17
Spindle cell rhabdomyosarcoma in adults. (16006807)
2005
18
Paratesticular spindle cell rhabdomyosarcoma diagnosed by fine needle aspiration cytology: a case report. (15966299)
2005
19
Spindle cell rhabdomyosarcoma of the tongue in an infant: a case report with emphasis on differential diagnosis of childhood spindle cell lesions. (15462501)
2004
20
Spindle-cell rhabdomyosarcoma with 2q36 approximately q37 involvement. (12550761)
2003
21
Paratesticular spindle cell rhabdomyosarcoma in an adult. (11458081)
2001
22
Spindle cell rhabdomyosarcoma in adults. A case report and literature review. (10674275)
2000
23
Cytogenetic study of a spindle-cell rhabdomyosarcoma of the parotid gland. (10087951)
1999
24
Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. (9537474)
1998
25
Spindle cell rhabdomyosarcoma: histologic variant of embryonal rhabdomyosarcoma with association to favorable prognosis. (7882713)
1995
26
Spindle cell rhabdomyosarcoma. A prognostically favorable variant of rhabdomyosarcoma. (1599014)
1992

Variations for Spindle Cell Rhabdomyosarcoma

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Expression for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Search GEO for disease gene expression data for Spindle Cell Rhabdomyosarcoma.

Pathways for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Pathways related to Spindle Cell Rhabdomyosarcoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1NCOA2, MYOD1
2
Show member pathways
Development Role of HDAC and calcium calmodulin dependent kinase CaMK in control of skeletal myogenesis58
9.1NCOA2, MYOD1
39.1NCOA2, MYOD1

Compounds for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Compounds related to Spindle Cell Rhabdomyosarcoma according to GeneCards Suite gene sharing:

(show all 23)
idCompoundScoreTop Affiliating Genes
1dihydrotestosterone43 28 24 1212.6DES, NCOA2
2triiodothyronine439.4NCOA2, MYOD1
3lactacystin439.4MYOD1, NCOA2
4estradiol43 24 1211.4NCOA2, DES
5mg 13243 5910.4MYOD1, NCOA2
6progesterone43 28 59 24 1213.3NCOA2, DES
7azathioprine43 2 49 1212.3DES, MYOD1
8bromodeoxyuridine439.3MYOD1, DES
912-o-tetradecanoylphorbol 13-acetate439.2MYOD1, DES
10acetylcholine43 49 28 24 1213.2DES, MYOD1
11actinomycin d439.1MYOD1, DES
12paraffin439.0DES, MYOD1
13fatty acid438.9MYOD1, DES
14lysine438.9NCOA2, MYOD1, DES
15cyclic amp43 249.9NCOA2, MYOD1, DES
16testosterone43 59 24 1211.9DES, MYOD1, NCOA2
17steroid438.8NCOA2, MYOD1, DES
18arginine438.8DES, MYOD1, NCOA2
19estrogen438.8NCOA2, MYOD1, DES
20retinoic acid43 249.8DES, MYOD1, NCOA2
21glucose438.8NCOA2, MYOD1, DES
22creatinine438.7MYOD1, DES
23tyrosine438.7NCOA2, MYOD1, DES

GO Terms for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Molecular functions related to Spindle Cell Rhabdomyosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription coactivator activityGO:00037139.1NCOA2, MYOD1
2nuclear hormone receptor bindingGO:00352578.8NCOA2, MYOD1

Products for genes affiliated with Spindle Cell Rhabdomyosarcoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Spindle Cell Rhabdomyosarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet