MCID: SPN009
MIFTS: 29

Spindle Cell Rhabdomyosarcoma malady

Summaries for Spindle Cell Rhabdomyosarcoma

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Wikipedia:65 Spindle cell rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma first described by Cavazzana,... more...

MalaCards based summary: Spindle Cell Rhabdomyosarcoma is related to rhabdomyosarcoma and embryonal rhabdomyosarcoma. An important gene associated with Spindle Cell Rhabdomyosarcoma is DES (desmin), and among its related pathways are L1CAM interactions and Immune response Function of MEF2 in T lymphocytes. The compounds dihydrotestosterone and triiodothyronine have been mentioned in the context of this disorder. Affiliated tissues include prostate and tongue.

Aliases & Classifications for Spindle Cell Rhabdomyosarcoma

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Spindle Cell Rhabdomyosarcoma, Aliases & Descriptions:

Name: Spindle Cell Rhabdomyosarcoma 10 62


External Ids:

Disease Ontology10 DOID:3260
NCIt40 C6519

Related Diseases for Spindle Cell Rhabdomyosarcoma

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Graphical network of diseases related to Spindle Cell Rhabdomyosarcoma:



Diseases related to spindle cell rhabdomyosarcoma

Symptoms for Spindle Cell Rhabdomyosarcoma

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Drugs & Therapeutics for Spindle Cell Rhabdomyosarcoma

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Drug clinical trials:

Search ClinicalTrials for Spindle Cell Rhabdomyosarcoma

Search NIH Clinical Center for Spindle Cell Rhabdomyosarcoma

Genetic Tests for Spindle Cell Rhabdomyosarcoma

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Anatomical Context for Spindle Cell Rhabdomyosarcoma

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MalaCards organs/tissues related to Spindle Cell Rhabdomyosarcoma:

33
Prostate, Tongue

Animal Models for Spindle Cell Rhabdomyosarcoma or affiliated genes

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Publications for Spindle Cell Rhabdomyosarcoma

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Articles related to Spindle Cell Rhabdomyosarcoma:

(show all 26)
idTitleAuthorsYear
1
Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma. (24272621)
2014
2
An adult spindle cell rhabdomyosarcoma in the head and neck region with long-term survival: a case report. (24946859)
2014
3
Spindle cell rhabdomyosarcoma in the hypopharynx of an adult. (25197406)
2014
4
Spindle cell rhabdomyosarcoma of the retroperitoneum: an unusual case developed in a pregnant woman but obscured by pregnancy. (25197361)
2014
5
Spindle cell rhabdomyosarcoma of the neck with t(6;8) translocation: report of a case and literature review. (23113671)
2013
6
Spindle cell rhabdomyosarcoma of the prostate. (23320845)
2013
7
Spindle cell rhabdomyosarcoma displaying CD34 positivity: a potential diagnostic pitfall; report of two pediatric cases. (24022313)
2013
8
Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis. (23899074)
2013
9
Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma. (23463663)
2013
10
Exfoliative cytologic findings of maxillary sinus spindle cell rhabdomyosarcoma. (20518428)
2010
11
Aggressive spindle cell rhabdomyosarcoma in an 11-month-old boxer dog. (20460837)
2010
12
Sclerosing spindle cell rhabdomyosarcoma in an adult: report of a new case and review of the literature. (19017660)
2010
13
Radiation-induced mandibular adult spindle cell rhabdomyosarcoma. (18023143)
2008
14
Clinicopathologic analysis of spindle cell rhabdomyosarcoma: report of 8 cases]. (18646700)
2008
15
Kit expression in spindle cell rhabdomyosarcoma can possibly create a different approach for its tumorigenesis and therapy. (16860492)
2006
16
Spindle cell rhabdomyosarcoma in adults: clinicopathological and immunohistochemical analysis of seven new cases. (17013628)
2006
17
Spindle cell rhabdomyosarcoma in adults. (16006807)
2005
18
Paratesticular spindle cell rhabdomyosarcoma diagnosed by fine needle aspiration cytology: a case report. (15966299)
2005
19
Spindle cell rhabdomyosarcoma of the tongue in an infant: a case report with emphasis on differential diagnosis of childhood spindle cell lesions. (15462501)
2004
20
Spindle-cell rhabdomyosarcoma with 2q36 approximately q37 involvement. (12550761)
2003
21
Paratesticular spindle cell rhabdomyosarcoma in an adult. (11458081)
2001
22
Spindle cell rhabdomyosarcoma in adults. A case report and literature review. (10674275)
2000
23
Cytogenetic study of a spindle-cell rhabdomyosarcoma of the parotid gland. (10087951)
1999
24
Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. (9537474)
1998
25
Spindle cell rhabdomyosarcoma: histologic variant of embryonal rhabdomyosarcoma with association to favorable prognosis. (7882713)
1995
26
Spindle cell rhabdomyosarcoma. A prognostically favorable variant of rhabdomyosarcoma. (1599014)
1992

Variations for Spindle Cell Rhabdomyosarcoma

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Expression for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Search GEO for disease gene expression data for Spindle Cell Rhabdomyosarcoma.

Pathways for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Pathways related to Spindle Cell Rhabdomyosarcoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1NCOA2, MYOD1
2
Show member pathways
Development Role of HDAC and calcium calmodulin dependent kinase CaMK in control of skeletal myogenesis60
9.1NCOA2, MYOD1
39.1NCOA2, MYOD1

Compounds for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Compounds related to Spindle Cell Rhabdomyosarcoma according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1dihydrotestosterone45 30 26 1312.6DES, NCOA2
2triiodothyronine459.4NCOA2, MYOD1
3lactacystin459.4MYOD1, NCOA2
4estradiol45 26 1311.4NCOA2, DES
5mg 13245 6110.4MYOD1, NCOA2
6progesterone45 30 61 26 1313.3NCOA2, DES
7azathioprine45 3 51 1312.3DES, MYOD1
8bromodeoxyuridine459.3MYOD1, DES
912-o-tetradecanoylphorbol 13-acetate459.2MYOD1, DES
10acetylcholine45 51 30 26 1313.2DES, MYOD1
11actinomycin d459.1MYOD1, DES
12paraffin459.0DES, MYOD1
13fatty acid458.9MYOD1, DES
14lysine458.9NCOA2, MYOD1, DES
15cyclic amp45 269.9NCOA2, MYOD1, DES
16testosterone45 61 26 1311.9DES, MYOD1, NCOA2
17steroid458.8NCOA2, MYOD1, DES
18arginine458.8DES, MYOD1, NCOA2
19estrogen458.8NCOA2, MYOD1, DES
20retinoic acid45 269.8DES, MYOD1, NCOA2
21glucose458.8NCOA2, MYOD1, DES
22creatinine458.7MYOD1, DES
23tyrosine458.7NCOA2, MYOD1, DES

GO Terms for genes affiliated with Spindle Cell Rhabdomyosarcoma

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Molecular functions related to Spindle Cell Rhabdomyosarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription coactivator activityGO:00037139.1NCOA2, MYOD1
2nuclear hormone receptor bindingGO:00352578.8NCOA2, MYOD1

Products for genes affiliated with Spindle Cell Rhabdomyosarcoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Spindle Cell Rhabdomyosarcoma

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet