MCID: SPN048
MIFTS: 20

Spindle Cell Thymoma

Categories: Cancer diseases, Immune diseases, Endocrine diseases

Aliases & Classifications for Spindle Cell Thymoma

MalaCards integrated aliases for Spindle Cell Thymoma:

Name: Spindle Cell Thymoma 12 14
Thymoma, Medullary 12
Medullary Thymoma 12
Thymoma, Type a 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3279
NCIt 47 C6454
SNOMED-CT 64 128707003
UMLS 69 C1266091

Summaries for Spindle Cell Thymoma

MalaCards based summary : Spindle Cell Thymoma, also known as thymoma, medullary, is related to malignant type a thymoma and spleen angiosarcoma. An important gene associated with Spindle Cell Thymoma is DES (Desmin). Related phenotype is Increased HPV16-GFP infection.

Related Diseases for Spindle Cell Thymoma

Diseases related to Spindle Cell Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
id Related Disease Score Top Affiliating Genes
1 malignant type a thymoma 11.0
2 spleen angiosarcoma 10.4 DES MUC1
3 myoma 10.4 DES MUC1
4 mucinous ovarian cystadenoma 10.4 DES MUC1
5 laryngeal neuroendocrine tumor 10.4 DES MUC1
6 mannose-binding lectin protein deficiency 10.4 DES MUC1
7 cellular ependymoma 10.4 DES MUC1
8 childhood pleomorphic rhabdomyosarcoma 10.4 DES MUC1
9 vulvar squamous papilloma 10.4 DES MUC1
10 spindle cell liposarcoma 10.4 DES MUC1
11 neurofibroma of the esophagus 10.4 DES MUC1
12 plummer vinson syndrome 10.4 DES MUC1
13 omphalocele 10.3 DES PAX8
14 pseudoachondroplastic dysplasia 2 10.3 DES MUC1
15 sebaceous adenoma 10.3 DES MUC1
16 short-rib thoracic dysplasia 12 10.3 DES MUC1
17 coronary restenosis 10.3 DES MUC1
18 extraskeletal mesenchymal chondrosarcoma 10.3 DES MUC1
19 spondyloepimetaphyseal dysplasia, isidor type 10.3 DES MUC1
20 exotropia 10.3 MUC1 PAX8
21 patent ductus arteriosus and bicuspid aortic valve with hand anomalies 10.3 DES MUC1
22 thymoma 10.3
23 thymic dysplasia 10.3 MUC1 PAX8
24 sarcomatoid mesothelioma 10.3 MUC1 PAX8
25 chondroblastoma 10.3 DES MUC1
26 esophagus leiomyoma 10.2 DES MUC1
27 invasive malignant thymoma 10.2 CD5 PAX8
28 linitis plastica 10.2 DES MUC1
29 spastic ataxia 3 10.2 MUC1 PAX8
30 cerebrum cancer 10.2 DES MUC1
31 dextrocardia with situs inversus 10.1 DES MUC1
32 dental caries 10.1 MUC1 PAX8
33 nasal cavity disease 10.1 MUC1 PAX8
34 preretinal fibrosis 10.1 DES MUC1
35 spermatogenic failure 13 10.0 DES MUC1
36 mixed type thymoma 10.0 CD5 MUC1
37 cd3delta deficiency 9.8 CD5 LCK
38 gastrointestinal system cancer 9.8 MUC1 PAX8
39 factor x deficiency 9.7
40 pemphigus vulgaris 9.7
41 melanoma 9.7
42 cervicitis 9.7
43 pemphigus 9.7
44 periventricular nodular heterotopia 6 9.7 DES MUC1
45 vaccinia 9.3 CD5 CD58 LCK
46 glandular-alveolar pattern testicular yolk sac tumor 9.3 CD5 CD58 LCK
47 dendritic cell thymoma 7.9 CD5 CD58 DES LCK MUC1 PAX8

Graphical network of the top 20 diseases related to Spindle Cell Thymoma:



Diseases related to Spindle Cell Thymoma

Symptoms & Phenotypes for Spindle Cell Thymoma

GenomeRNAi Phenotypes related to Spindle Cell Thymoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased HPV16-GFP infection GR00350-A 8.8 DES LCK PAX8

Drugs & Therapeutics for Spindle Cell Thymoma

Search Clinical Trials , NIH Clinical Center for Spindle Cell Thymoma

Genetic Tests for Spindle Cell Thymoma

Anatomical Context for Spindle Cell Thymoma

Publications for Spindle Cell Thymoma

Articles related to Spindle Cell Thymoma:

(show all 12)
id Title Authors Year
1
Concurrent spindle-cell thymoma and thymic cysts in a Barbary sheep (Ammotragus lervia): case report and review of the literature. ( 27698165 )
2016
2
The histomorphologic spectrum of spindle cell thymoma. ( 23260329 )
2012
3
Fine-needle aspiration biopsy of ectopic cervical spindle-cell thymoma: a case report. ( 15880711 )
2005
4
Malignant melanoma of mediastinum misdiagnosed as a spindle cell thymoma in a fine needle aspirate: a case report. ( 16124173 )
2005
5
Primary intrapulmonary spindle cell thymoma with marked granulomatous reaction: report of a case with review of literature. ( 14615837 )
2003
6
Images in clinical medicine. Spindle-cell thymoma. ( 14534337 )
2003
7
Pericardial rhabdomyomatous spindle cell thymoma with mucinous cystic degeneration. ( 11422489 )
2001
8
Pemphigus vulgaris associated with spindle cell thymoma. ( 8080421 )
1993
9
Thymic carcinosarcoma associated with a spindle cell thymoma: an immunohistochemical study. ( 1398523 )
1992
10
Novel factor X deficiency. Normal partial thromboplastin time and associated spindle cell thymoma. ( 4014297 )
1985
11
A spindle cell varient of thymic carcinoid tumor. A clinical, histologic, and fine structural study with emphasis on its distinction from spindle cell thymoma. ( 946757 )
1976
12
Epithelial nature of spindle-cell thymoma. An ultrastructural study. ( 5051674 )
1972

Variations for Spindle Cell Thymoma

Expression for Spindle Cell Thymoma

Search GEO for disease gene expression data for Spindle Cell Thymoma.

Pathways for Spindle Cell Thymoma

GO Terms for Spindle Cell Thymoma

Biological processes related to Spindle Cell Thymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 T cell costimulation GO:0031295 8.62 CD5 LCK

Sources for Spindle Cell Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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