MCID: SPN048
MIFTS: 21

Spindle Cell Thymoma

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Spindle Cell Thymoma

MalaCards integrated aliases for Spindle Cell Thymoma:

Name: Spindle Cell Thymoma 12 14
Thymoma, Medullary 12
Medullary Thymoma 12
Thymoma, Type a 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3279
NCIt 46 C6454
SNOMED-CT 64 128707003
UMLS 69 C1266091

Summaries for Spindle Cell Thymoma

MalaCards based summary : Spindle Cell Thymoma, also known as thymoma, medullary, is related to thymoma and malignant type a thymoma. An important gene associated with Spindle Cell Thymoma is DES (Desmin). Related phenotype is Increased HPV16-GFP infection.

Related Diseases for Spindle Cell Thymoma

Diseases related to Spindle Cell Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 thymoma 29.6 CD5 LCK
2 malignant type a thymoma 11.1
3 thymoma, familial 10.4
4 parachordoma 10.3 DES MUC1
5 ossifying fibromyxoid tumor 10.3 DES MUC1
6 spindle cell rhabdomyosarcoma 10.2 DES MUC1
7 biphasic synovial sarcoma 10.2 DES MUC1
8 myxofibrosarcoma 10.2 DES MUC1
9 syringocystadenoma papilliferum 10.2 DES MUC1
10 syringoma 10.2 DES MUC1
11 pleomorphic liposarcoma 10.2 DES MUC1
12 ischemic fasciitis 10.2 DES MUC1
13 plasmablastic lymphoma 10.2 DES MUC1
14 proximal spinal muscular atrophy 10.2 DES MUC1
15 perivascular epithelioid cell tumor 10.2 DES MUC1
16 reticulum cell sarcoma 10.2 DES MUC1
17 spindle cell sarcoma 10.2 DES MUC1
18 mesenchymal chondrosarcoma 10.2 DES MUC1
19 extraskeletal ewing sarcoma 10.2 DES MUC1
20 hemangiopericytoma, malignant 10.2 DES MUC1
21 benign mesothelioma 10.2 DES MUC1
22 endosalpingiosis 10.2 MUC1 PAX8
23 malignant fibroxanthoma 10.2 DES MUC1
24 sarcomatoid renal cell carcinoma 10.2 MUC1 PAX8
25 fasciitis 10.2 DES MUC1
26 nephrogenic adenoma 10.1 MUC1 PAX8
27 spindle cell carcinoma 10.1 DES MUC1
28 chordoma 10.1 DES MUC1
29 mixed type thymoma 10.1 CD5 PAX8
30 rhabdoid cancer 10.1 DES MUC1
31 desmoplastic small round cell tumor 10.1 DES MUC1
32 giant cell tumor 10.1 DES MUC1
33 malignant ovarian surface epithelial-stromal neoplasm 10.0 MUC1 PAX8
34 malignant epithelial mesothelioma 10.0 CD5 PAX8
35 ovary epithelial cancer 10.0 MUC1 PAX8
36 sarcoma, synovial 9.9 DES MUC1
37 thymus cancer 9.9 CD5 MUC1
38 ovarian cancer 1 9.9 MUC1 PAX8
39 cd45 deficiency 9.8 CD5 LCK
40 pemphigus vulgaris, familial 9.8
41 factor x deficiency 9.8
42 pemphigus vulgaris 9.8
43 melanoma 9.8
44 cervicitis 9.8
45 pemphigus 9.8
46 papillary carcinoma 9.8 MUC1 PAX8
47 dendritic cell thymoma 9.4 CD5 CD58 LCK
48 epithelial malignant thymoma 9.4 CD5 CD58 LCK

Graphical network of the top 20 diseases related to Spindle Cell Thymoma:



Diseases related to Spindle Cell Thymoma

Symptoms & Phenotypes for Spindle Cell Thymoma

GenomeRNAi Phenotypes related to Spindle Cell Thymoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased HPV16-GFP infection GR00350-A 8.8 PAX8 DES LCK

Drugs & Therapeutics for Spindle Cell Thymoma

Search Clinical Trials , NIH Clinical Center for Spindle Cell Thymoma

Genetic Tests for Spindle Cell Thymoma

Anatomical Context for Spindle Cell Thymoma

Publications for Spindle Cell Thymoma

Articles related to Spindle Cell Thymoma:

(show all 12)
# Title Authors Year
1
Concurrent spindle-cell thymoma and thymic cysts in a Barbary sheep (Ammotragus lervia): case report and review of the literature. ( 27698165 )
2016
2
The histomorphologic spectrum of spindle cell thymoma. ( 23260329 )
2012
3
Malignant melanoma of mediastinum misdiagnosed as a spindle cell thymoma in a fine needle aspirate: a case report. ( 16124173 )
2005
4
Fine-needle aspiration biopsy of ectopic cervical spindle-cell thymoma: a case report. ( 15880711 )
2005
5
Images in clinical medicine. Spindle-cell thymoma. ( 14534337 )
2003
6
Primary intrapulmonary spindle cell thymoma with marked granulomatous reaction: report of a case with review of literature. ( 14615837 )
2003
7
Pericardial rhabdomyomatous spindle cell thymoma with mucinous cystic degeneration. ( 11422489 )
2001
8
Pemphigus vulgaris associated with spindle cell thymoma. ( 8080421 )
1993
9
Thymic carcinosarcoma associated with a spindle cell thymoma: an immunohistochemical study. ( 1398523 )
1992
10
Novel factor X deficiency. Normal partial thromboplastin time and associated spindle cell thymoma. ( 4014297 )
1985
11
A spindle cell varient of thymic carcinoid tumor. A clinical, histologic, and fine structural study with emphasis on its distinction from spindle cell thymoma. ( 946757 )
1976
12
Epithelial nature of spindle-cell thymoma. An ultrastructural study. ( 5051674 )
1972

Variations for Spindle Cell Thymoma

Expression for Spindle Cell Thymoma

Search GEO for disease gene expression data for Spindle Cell Thymoma.

Pathways for Spindle Cell Thymoma

GO Terms for Spindle Cell Thymoma

Biological processes related to Spindle Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell costimulation GO:0031295 8.62 CD5 LCK

Sources for Spindle Cell Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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