MCID: SPL005
MIFTS: 32

Splenic Artery Aneurysm malady

Category: Cardiovascular diseases

Aliases & Classifications for Splenic Artery Aneurysm

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Aliases & Descriptions for Splenic Artery Aneurysm:

Name: Splenic Artery Aneurysm 11 13
 
Aneurysm of Splenic Artery 68

Classifications:



External Ids:

Disease Ontology11 DOID:14006
SNOMED-CT62 70405009
ICD9CM32 442.83

Summaries for Splenic Artery Aneurysm

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MalaCards based summary: Splenic Artery Aneurysm, also known as aneurysm of splenic artery, is related to aneurysm and pancreatitis. An important gene associated with Splenic Artery Aneurysm is SAA1 (Serum Amyloid A1), and among its related pathways are FOXA1 transcription factor network and Surfactant metabolism. Affiliated tissues include liver, spleen and pancreas, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and hematopoietic system.

Related Diseases for Splenic Artery Aneurysm

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Graphical network of the top 20 diseases related to Splenic Artery Aneurysm:



Diseases related to splenic artery aneurysm

Symptoms & Phenotypes for Splenic Artery Aneurysm

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GenomeRNAi Phenotypes related to Splenic Artery Aneurysm according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-8410.0CD163, HCK, NF1

MGI Mouse Phenotypes related to Splenic Artery Aneurysm according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.9APCS, CD163, HCK, NF1, SFTPA1, SLC4A1
2MP:00053767.4APCS, ATP8B1, CD163, HCK, NF1, SAA1

Drugs & Therapeutics for Splenic Artery Aneurysm

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Comparison Between Open and Laparoscopic Splenic Aneurysms RepairCompletedNCT01387828Phase 3

Search NIH Clinical Center for Splenic Artery Aneurysm

Genetic Tests for Splenic Artery Aneurysm

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Anatomical Context for Splenic Artery Aneurysm

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MalaCards organs/tissues related to Splenic Artery Aneurysm:

36
Liver, Spleen, Pancreas, Kidney, Colon

Publications for Splenic Artery Aneurysm

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Articles related to Splenic Artery Aneurysm:

(show top 50)    (show all 336)
idTitleAuthorsYear
1
Splenic artery aneurysm. (27982336)
2016
2
Giant splenic artery aneurysm rupture. (27398212)
2016
3
Splenic artery aneurysm presenting as a submucosal gastric lesion: A case report. (27499832)
2016
4
Surgical management of a splenic artery aneurysm. (27190621)
2016
5
Rebleeding of a Splenic Artery Aneurysm after Coil Embolisation. (27872785)
2016
6
Successful resuscitation after splenic artery aneurysm rupture. (26957826)
2016
7
Splenic artery aneurysm rupture in pregnancy. (28069418)
2016
8
Multiple Giant Splenic Artery Aneurysms Causing Sinistral (Left-Sided) Portal Hypertension. (27110411)
2016
9
Spontaneous rupture of the splenic artery aneurysm: a rare clinical presentation of acute abdomen. (27135088)
2016
10
Computed Tomography Angiography in Diagnosis and Treatment of Splenic Artery Aneurysm. (26831243)
2016
11
Saved from a fatal flight: A ruptured splenic artery aneurysm in a pregnant woman. (25617728)
2015
12
A case of ruptured giant splenic artery aneurysm. (25744926)
2015
13
Endovascular repair of a complex splenic artery aneurysm using a multilayer stent. (25918769)
2015
14
Embolization of a True Giant Splenic Artery Aneurysm Using NBCA Glue - Case Report and Literature Review. (25848440)
2015
15
Hepatobiliary and Pancreatic: A splenic artery aneurysm presenting as a calcified pancreatic mass. (25776962)
2015
16
Idiopathic splenic arteriovenous fistula without splenic artery aneurysm. (25903210)
2015
17
Giant splenic artery aneurysm. (25604380)
2015
18
Combined endovascular embolization and open surgery for splenic artery aneurysm with arteriovenous fistula. (26522588)
2015
19
Splenic artery aneurysm bleeding via the ampulla of Vater. (26397850)
2015
20
Postmortem Computed Tomography Findings in Ruptured Splenic Artery Aneurysm: Value of the Clinical "Sentinel Clot" Sign in Identification of Bleeding Location. (26164764)
2015
21
Splenic Artery Aneurysm in Pregnancy. (26605452)
2015
22
Splenic Artery Aneurysm Invaded by Desmoid-Type Fibromatosis. (26017693)
2015
23
Ruptured splenic artery aneurysm detected by emergency ultrasound-a case report. (26069053)
2015
24
Endovascular Treatment of Splenic Artery Aneurysm With a Stent-Graft: A Case Report. (26717355)
2015
25
Uncommon cause of life-threatening retroperitoneal hemorrhage in a healthy young Hispanic patient: splenic artery aneurysm rupture. (26035985)
2015
26
Management of Giant Splenic Artery Aneurysm: Comprehensive Literature Review. (26166071)
2015
27
Ruptured Splenic Artery Aneurysm: Rare Cause of Shock Diagnosed with Bedside Ultrasound. (26587106)
2015
28
Rupture of maternal splenic artery aneurysm and fetal demise. (26152017)
2015
29
Rupture of splenic artery aneurysm in primipara five days after cesarean section: case report and review of the literature. (26373746)
2015
30
Endoscopic ultrasound-guided thrombin injection in a large splenic artery aneurysm: first report in a patient with tropical chronic pancreatitis. (25121631)
2014
31
Splenic artery aneurysm presenting with abdominal discomfort and weight loss. (25092196)
2014
32
Ruptured splenic artery aneurysm in pregnancy: a case series. (25179954)
2014
33
Ruptured spontaneous splenic artery aneurysm: A case report and review of the literature. (25240215)
2014
34
A case of ruptured splenic artery aneurysm in pregnancy. (25574408)
2014
35
Successful treatment of aberrant splenic artery aneurysm with a combination of coils embolization and covered stents. (25176112)
2014
36
Multiple splenic artery aneurysms: a rare cause of extrahepatic portal hypertension and massive splenomegaly. (25386475)
2014
37
Page kidney secondary to large splenic artery aneurysm bleeding and its management by angioembolization. (25032140)
2014
38
Endovascular retreatment of a splenic artery aneurysm refilled by collateral branches of the left gastric artery: a case report. (25515847)
2014
39
Splenic artery aneurysm: pre-rupture diagnosis is life saving. (25427929)
2014
40
Laparoscopic ligation of proximal splenic artery aneurysm with splenic function preservation. (24782641)
2014
41
Splenic artery aneurysm as an unusual cause of new onset ascites: a case report. (24829704)
2014
42
Early aortal clamping in the surgical treatment of splenic artery aneurysm rupture. (24625628)
2014
43
Anomalous splenic artery aneurysm. (23526109)
2013
44
Multiple splenic artery aneurysms in a patient with portal hypertension. (23484244)
2013
45
Laparoscopic excision of splenic artery aneurysm. (23743385)
2013
46
Splenic artery aneurysm rupture during pregnancy. (24589051)
2013
47
Laparoscopic resection for splenic artery aneurysm using the lateral approach: report of two cases. (23602003)
2013
48
Endovascular Repair of a Complex Splenic Artery Aneurysm Using a Multilayer Stent. (24232043)
2013
49
Stent-assisted coil embolization of a complex wide-neck splenic artery aneurysm. (23988548)
2013
50
Splenic Artery Aneurysm: An Important Cause of Hemoperitoneum and Shock. (24140017)
2013

Variations for Splenic Artery Aneurysm

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Expression for genes affiliated with Splenic Artery Aneurysm

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Search GEO for disease gene expression data for Splenic Artery Aneurysm.

Pathways for genes affiliated with Splenic Artery Aneurysm

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Pathways related to Splenic Artery Aneurysm according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6SFTPA1, SFTPA2
2
Show member pathways
9.6SFTPA1, SFTPA2
3
Show member pathways
9.6SFTPA1, SFTPA2
4
Show member pathways
8.8SFTPA1, SFTPA2, UBC

GO Terms for genes affiliated with Splenic Artery Aneurysm

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Cellular components related to Splenic Artery Aneurysm according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1clathrin-coated endocytic vesicleGO:004533410.4SFTPA1, SFTPA2
2lamellar bodyGO:00425999.6SFTPA1, SFTPA2
3extracellular regionGO:00055768.6APCS, CD163, PCSK1N, SAA1, SFTPA1, SFTPA2
4extracellular spaceGO:00056157.6APCS, PCSK1N, SAA1, SFTPA1, SFTPA2, UBC

Biological processes related to Splenic Artery Aneurysm according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:000758510.1SFTPA1, SFTPA2
2acute-phase responseGO:000695310.0APCS, CD163, SAA1
3toll-like receptor signaling pathwayGO:00022249.6SFTPA1, SFTPA2
4innate immune responseGO:00450878.9APCS, HCK, SAA1, UBC
5cellular protein metabolic processGO:00442678.7APCS, SAA1, SFTPA1, SFTPA2, UBC

Molecular functions related to Splenic Artery Aneurysm according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipid transporter activityGO:00053199.8ATP8B1, SFTPA1
2carbohydrate bindingGO:00302469.5APCS, SFTPA1, SFTPA2

Sources for Splenic Artery Aneurysm

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet