MCID: SPL003
MIFTS: 20

Splenic Flexure Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Splenic Flexure Cancer

MalaCards integrated aliases for Splenic Flexure Cancer:

Name: Splenic Flexure Cancer 12 14
Malignant Neoplasm of Splenic Flexure of Colon 69
Malignant Neoplasm of Splenic Flexure 12
Malignant Tumor of Splenic Flexure 12
Ca Splenic Flexure - Colon 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12191
ICD10 33 C18.5
ICD9CM 35 153.7
UMLS 69 C0153440

Summaries for Splenic Flexure Cancer

MalaCards based summary : Splenic Flexure Cancer, also known as malignant neoplasm of splenic flexure of colon, is related to punctate epithelial keratoconjunctivitis and filarial elephantiasis. An important gene associated with Splenic Flexure Cancer is GLE1 (GLE1, RNA Export Mediator). The drugs Cola and Pancrelipase have been mentioned in the context of this disorder. Affiliated tissues include colon and lymph node.

Related Diseases for Splenic Flexure Cancer

Diseases related to Splenic Flexure Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 punctate epithelial keratoconjunctivitis 9.5 GLE1 PCLO
2 filarial elephantiasis 9.2 GLE1 PCLO

Comorbidity relations with Splenic Flexure Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Colorectal Cancer
Deficiency Anemia Intestinal Obstruction
Paralytic Ileus

Symptoms & Phenotypes for Splenic Flexure Cancer

Drugs & Therapeutics for Splenic Flexure Cancer

Drugs for Splenic Flexure Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cola Nutraceutical Phase 2, Phase 3,Early Phase 1
2
Pancrelipase Approved 53608-75-6
3 pancreatin

Interventional clinical trials:

(show all 11)

id Name Status NCT ID Phase Drugs
1 Short Term Outcomes of Laparoscopic Intersphincteric Resection for Low Rectal Cancer Unknown status NCT01836926 Phase 2, Phase 3
2 Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer Recruiting NCT03242187 Phase 2, Phase 3
3 Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR). Unknown status NCT02488707 Phase 2
4 Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE) Unknown status NCT01006577
5 Laparoscopic Splenic Flexure Mobilization Completed NCT03001375
6 Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening Completed NCT02041507
7 The Effect of Routine Video-recording on Colonoscopy Quality Indicators. Completed NCT02054923
8 Positioning During Colonoscopy Completed NCT01254435 Early Phase 1
9 Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery Recruiting NCT03013153
10 Natural Orifice Transluminal Endoscopic Surgery for Colorectal Cancer Recruiting NCT02549456
11 Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence Recruiting NCT03283540

Search NIH Clinical Center for Splenic Flexure Cancer

Genetic Tests for Splenic Flexure Cancer

Anatomical Context for Splenic Flexure Cancer

MalaCards organs/tissues related to Splenic Flexure Cancer:

39
Colon, Lymph Node

Publications for Splenic Flexure Cancer

Articles related to Splenic Flexure Cancer:

id Title Authors Year
1
Iatrogenic diaphragmatic hernia following laparoscopic left colectomy for splenic flexure cancer An unusual complication. ( 28232645 )
2016
2
Laparoscopic colonic resection for splenic flexure cancer: our experience. ( 26148781 )
2015

Variations for Splenic Flexure Cancer

Expression for Splenic Flexure Cancer

Search GEO for disease gene expression data for Splenic Flexure Cancer.

Pathways for Splenic Flexure Cancer

GO Terms for Splenic Flexure Cancer

Sources for Splenic Flexure Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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