MCID: SPL006
MIFTS: 35

Splenic Infarction malady

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Splenic Infarction

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Aliases & Descriptions for Splenic Infarction:

Name: Splenic Infarction 11 50 39 13 68
Infarct of the Spleen 48
 
Splenic Infarcts 48
Splenic Infarct 11

Classifications:



External Ids:

Disease Ontology11 DOID:2533
ICD1030 D73.5
MeSH39 D013159

Summaries for Splenic Infarction

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Wikipedia:71 Splenic infarction is a condition in which oxygen supply to the spleen is interrupted, leading to... more...

MalaCards based summary: Splenic Infarction, also known as infarct of the spleen, is related to cholesterol embolism and bartholin's gland adenoma. An important gene associated with Splenic Infarction is HBB (Hemoglobin Subunit Beta), and among its related pathways Affiliated tissues include spleen, liver and monocytes.

Related Diseases for Splenic Infarction

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Diseases related to Splenic Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 128)
idRelated DiseaseScoreTop Affiliating Genes
1cholesterol embolism29.6APOH, F2
2bartholin's gland adenoma10.3F2, HBB
3subcortical arteriosclerotic encephalopathy10.3APOH, F2
4unicentric castleman disease10.3APOH, F2
5classic congenital lipoid adrenal hyperplasia due to star deficency10.3APOH, F2
6collagenous colitis10.3APOH, F2
7thrombophilia due to thrombin defect10.2APOH, F2
8may-hegglin anomaly10.2APOH, F2
9left-right axis malformations10.2APOH, F2
10transient cerebral ischemia10.2APOH, F2
11chronic inflammatory demyelinating polyneuritis10.2F2, HBB
12budd-chiari syndrome10.2APOH, F2
13elejalde disease10.2APOH, F2
14thrombophilia10.2APOH, F2
15selective iga deficiency disease10.2APOH, F2
16lingual-facial-buccal dyskinesia10.2APOH, F2
17intracranial arteriosclerosis10.2APOH, F2
18spastic paraplegia 3a10.2F2, HBB
19noma10.2APOH, F2
20joint disorders10.2APOH, F2
21sacrococcygeal teratoma10.2APOH, F2
22ischemic heart disease10.1APOH, F2
23c1 inhibitor deficiency10.1APOH, F2
24cervical mullerian papilloma10.1APOH, F2
25thrombophilia due to activated protein c resistance10.1APOH, F2
26prostate neuroendocrine neoplasm10.1APOH, F2
27factor v deficiency10.1APOH, F2
28ulcerative blepharitis10.1APOH, F2
29mixed mineral dust pneumoconiosis10.0APOH, F2
30malaria10.0
31pancreatitis10.0
32pregnancy loss, recurrent 210.0APOH, F2
33endocarditis10.0
34blood group incompatibility10.0APOH, F2
35thalassemia-beta, dominant inclusion-body9.9F2, HBB
36hereditary spherocytosis9.9
37leukemia9.9
38aneurysm9.9
39photokeratitis9.8APOH, F2
40hemolytic anemia9.8
41hepatitis9.8
42infective endocarditis9.8
43acute pancreatitis9.8
44autoimmune hemolytic anemia9.8
45peritonitis9.8
46polycythemia9.8
47thrombocytopenia9.8
48splenic sequestration9.8
49plasmodium vivax malaria9.8
50hemoglobin c disease9.8

Graphical network of the top 20 diseases related to Splenic Infarction:



Diseases related to splenic infarction

Symptoms & Phenotypes for Splenic Infarction

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Drugs & Therapeutics for Splenic Infarction

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Drugs for Splenic Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Peginterferon alfa-2bapprovedPhase 330899210-65-8, 215647-85-1
Synonyms:
215647-85-1
D02748
PEG-Intron
PegIntron
 
Peginterferon alfa-2b
Peginterferon alfa-2b (INN)
Peginterferon alfa-2b (generical recombination)
Peginterferon alfa-2b (generical recombination) (JAN)
Pegintron (TN)
Unitron PEG
2Anti-Infective AgentsPhase 3, Phase 221402
3interferonsPhase 32137
4Antiviral AgentsPhase 3, Phase 29732
5Interferon-alphaPhase 31139
6prolineNutraceuticalPhase 327
7JM 3100Phase 2132
8Anti-HIV AgentsPhase 23100
9Anti-Retroviral AgentsPhase 23232
10
Mannitolapproved, investigationalPhase 126869-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
11diureticsPhase 11372
12Natriuretic AgentsPhase 11645
13Liver Extracts3868

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Vera PatientsCompletedNCT02523638Phase 3
2AOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.Active, not recruitingNCT02218047Phase 3
3AMD3100 to Mobilize Stem Cells for DonationCompletedNCT00075335Phase 2
4Phase I Clinical Safety Study About Human Umbilical Cord Blood Monocyte in the Acute Ischemic StrokeRecruitingNCT02433509Phase 1
5Microwave Ablation and Partial Splenic Embolization in the Management of HypersplenismUnknown statusNCT02261584
6The Spleen in Sickle Cell Anemia and Sickle Cell ThalassemiaCompletedNCT00971698
7Immunological Profile in Relation to Cardiac Geometry in HypertensionRecruitingNCT02165241

Search NIH Clinical Center for Splenic Infarction


Cochrane evidence based reviews: splenic infarction

Genetic Tests for Splenic Infarction

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Anatomical Context for Splenic Infarction

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MalaCards organs/tissues related to Splenic Infarction:

36
Spleen, Liver, Monocytes, Myeloid, B cells

Publications for Splenic Infarction

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Articles related to Splenic Infarction:

(show top 50)    (show all 290)
idTitleAuthorsYear
1
Sequential Insults: Acute Lyme Disease with Splenic Infarction. (26688425)
2016
2
Splenic infarction associated with acute infectious mononucleosis due to Epstein-Barr virus infection. (27357912)
2016
3
A Case of Isolated Celiac Artery Dissection Accompanied by Splenic Infarction Detected by Ultrasonography in the Emergency Department. (27148460)
2016
4
Group B Streptococcal Tricuspid Valve Endocarditis with Splenic Infarction after an Elective Abortion. (27617630)
2016
5
Splenic infarction as a pitfall on labeled red blood cell imaging. (26917904)
2016
6
Splenic Infarction in Acute Infectious Mononucleosis. (26602427)
2016
7
Massive splenic infarction and splenic venous thrombosis observed in a patient with acute splenic syndrome of sickle cell traits on contrast-enhanced thin-slice computed tomography. (27251735)
2016
8
Splenic Infarction in Polycythemia Vera: Can the Spleen be Saved? (26731841)
2015
9
Splenic infarction after reversal of warfarin using Prothrombinex-VF in a patient with a mechanical aortic valve. (26224191)
2015
10
Evaluation with contrast ultrasound of the prevalence of splenic infarction in left-sided infective endocarditis. (26261464)
2015
11
An adolescent with hereditary spherocytosis who presented with splenic infarction. (26139647)
2015
12
The unexpected finding of a splenic infarction in a patient with infectious mononucleosis due to Epstein-Barr virus. (26607191)
2015
13
Splenic infarction - A rare cause of acute abdominal pain following gastric surgery: A case series. (25818369)
2015
14
Splenic infarction associated with sickle cell trait at low altitude. (26133225)
2015
15
Mycosis fungoides associated with splenic infarction and muscle involvement. (25994394)
2015
16
Incidentally Discovered Splenic Infarction Associated with Scrub Typhus. (26333728)
2015
17
Splenic infarction and G-CSF. (26840787)
2015
18
Brachial artery mycotic aneurysm and splenic infarction associated with infective endocarditis. (26186921)
2015
19
Dangerous proximity: splenic infarction after abdominal abscess. (25448176)
2015
20
Acute Splenic Infarction at an Academic General Hospital Over 10 Years: Presentation, Etiology, and Outcome. (26356690)
2015
21
A Diagnostic Pitfall: Salmonella Splenic Infarction in Hereditary Spherocytosis. (26272774)
2015
22
Splenic infarction in polycythaemia vera: can the spleen be saved? (25327078)
2014
23
Asymptomatic partial splenic infarction in laparoscopic floppy nissen fundoplication and brief literature review. (24833155)
2014
24
Malaria-Induced Splenic Infarction. (25294615)
2014
25
Massive splenic infarction and portal vein thrombosis in children with chronic myeloid leukemia. (24942025)
2014
26
Splenic infarction due to disseminated primary CMV infection. (25159098)
2014
27
Conservative treatment of splenic infarction and intestinal obstruction caused by a wandering spleen. (24700108)
2014
28
The sonographic "bright band sign" of splenic infarction. (24866600)
2014
29
Massive splenic infarction leading to sickle cell disease. (25075666)
2014
30
Splenic infarction and malaria. (24942899)
2014
31
Spontaneous massive splenic infarction in the setting of renal transplant and septic shock: a case report and review of the literature. (25317176)
2014
32
Splenic infarction in Plasmodium vivax malaria. (24825280)
2014
33
A novel frameshift mutation in exon 4 causing a deficiency of high-molecular-weight kininogen in a patient with splenic infarction. (24492696)
2014
34
Splenic infarction caused by a rare coinfection of Epstein-Barr virus, cytomegalovirus, and Mycoplasma pneumoniae. (25186505)
2014
35
Splenic infarction in P.vivax malaria. (24096848)
2013
36
Splenic infarction as a rare complication of infectious mononucleosis due to Epstein-Barr virus infection in a patient with no significant comorbidity: case report and review of the literature. (23957538)
2013
37
Splenic infarction after N-butyl-2-cyanoacrylate injection for gastric varices: why does it happen? (24105294)
2013
38
Acute splenic infarction in a hiker with previously unrecognised sickle cell trait. (23632180)
2013
39
Massive splenic infarction in an adolescent with hemoglobin S-HPFH. (23281181)
2013
40
Multiple splenic infarcts in acute Plasmodium vivax malaria: a rare case report. (23608386)
2013
41
Splenic infarction at high altitude secondary to sickle cell trait. (22944537)
2013
42
Hepatic and splenic infarction and bowel ischemia following endoscopic ultrasound-guided celiac plexus neurolysis. (23767046)
2013
43
Q Fever with transient antiphospholipid antibodies associated with cholecystitis and splenic infarction. (23271442)
2013
44
Meningitis and splenic infarction due to disseminated Mycobacterium genavense infection in an HIV patient. Case report and review of the literature. (24156225)
2013
45
Spontaneous (atraumatic) splenic rupture complicating anticoagulant treatment for splenic infarction. (24187770)
2013
46
Splenic infarction in a child with primary Epstein-Barr virus infection. (24134766)
2013
47
A unique cause of intestinal and splenic infarction in a sickle cell trait patient. (23738181)
2013
48
Sterile peritonitis because of splenic infarction in a patient on peritoneal dialysis: an unusual presentation. (23660616)
2013
49
Splenic infarction in thalassemia major. (23053186)
2013
50
Acute abdomen due to splenic infarction as the initial presentation of pediatric acute lymphoblastic leukemia. (23386231)
2013

Variations for Splenic Infarction

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Expression for genes affiliated with Splenic Infarction

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Search GEO for disease gene expression data for Splenic Infarction.

Pathways for genes affiliated with Splenic Infarction

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Pathways related to Splenic Infarction according to GeneCards Suite gene sharing:

   (show less)
idSuper pathwaysTop Affiliating Genes

GO Terms for genes affiliated with Splenic Infarction

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Biological processes related to Splenic Infarction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood coagulation, intrinsic pathwayGO:000759710.0APOH, F2
2negative regulation of fibrinolysisGO:005191810.0APOH, F2
3positive regulation of blood coagulationGO:00301949.9APOH, F2
4regulation of blood coagulationGO:00301939.5APOH, F2

Sources for Splenic Infarction

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet