Splenic Infarction malady

Wikipedia: In medicine, splenic infarction is a condition in which oxygen supply to the spleen is interrupted,...⁴⁴ more...

MalaCards: Splenic Infarction, also known as splenic infarction (disorder), is related to thalassemia and retinal vascular occlusion. An important gene associated with Splenic Infarction is APOH (apolipoprotein H (beta-2-glycoprotein I)). The compounds neomycin and azathioprine have been mentioned in the context of this disorder. Affiliated tissues include spleen.

Aliases & Descriptions:

splenic infarction 6 8 32 43 splenic infarction (disorder) 6 infarct of the spleen 30

splenic infarcts 30 splenic infarct 6

Diseases related to splenic infarction by text searches and GeneDecks gene sharing:

(show all 22)

id	Related Disease	Score	Top Affiliating Genes
1	thalassemia	27.5	APOH, HBB, BLM
2	retinal vascular occlusion	12.8	APOH, PIGA
3	alpha thalassemia	12.7	HBB, APOH
4	autoimmune hemolytic anemia	12.6	PIGA, APOH
5	familial hypercholesterolemia	12.6	HBB, APOH
6	acute chest syndrome	12.3	BLM, HBB
7	thrombophilia	12.3	APOH, PIGA
8	hemolytic anemia	12.3	PIGA, HBB, APOH
9	hemoglobinopathy	12.3	BLM, HBB
10	thrombosis	12.0	PIGA, APOH, HBB
11	mayer-rokitansky-kuster-hauser syndrome	11.7	PIGA, BLM, HBB
12	anemia	10.9	PIGA, CEACAM5, BLM, APOH, HBB
13	acute pancreatitis	6.4
14	antiphospholipid syndrome	6.4
15	beta thalassemia	6.4
16	immunodeficiency	6.4
17	lupus erythematosus	6.4
18	leptospirosis	6.4
19	pancreatitis	6.4
20	sickle cell disease	6.4
21	systemic lupus erythematosus	6.4
22	acquired immunodeficiency syndrome	6.4

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to splenic infarction:

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Articles related to splenic infarction:

id	Title	Authors	Year	Affiliating Genes
1	A case of acute pancreatitis and splenic infarction associated with antiphospholipid syndrome (19158473)	Koh K.H.... Kim J.H.	2009	APOH
2	Acute splenic infarct in beta-thalassemia minor: a no vel combination of heterozygous beta-globin mutations with latent phenotypes an d the clinical implications. (19657842)	Liaw D.C.... Kender M.A.	2009	HBB
3	Splenic infarct as a diagnostic pitfall in radiology. (18688130)	Joshi S.C.... Anshari M.A.	2008	CEACAM5
4	Acute abdominal pain due to splenic infarction in a patient with heterozygous sickle cell disease exposed to high altitude (17211489)	Ruiz Semba E.... ChA!vez Gil V.	2006	HBB
5	Splenic infarction in a pregnant woman with systemic lupus erythematosus. (15714383)	Soy M.... UnlA1 E.	2005	APOH
6	Splenic infarction associated with anti-cardiolipin antibody: a report of two cases. (14964553)	McVay C.L.... Silberman A.W.	2004	APOH
7	Splenic infarction in a patient with anticardiolipin antibodies and leptospirosis (10193074)	Noval J.... BarA^ U.	1999	APOH
8	Splenic infarction associated with anticardiolipin an tibodies in a patient with acquired immunodeficiency syndrome. (8508712)	Cappell M.S.... Tiku M.	1993	APOH

Genes related to splenic infarction according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	APOH	apolipoprotein H (beta-2-glycoprotein I)	11.0	Publications
2	GBAS	glioblastoma amplified sequence	11.0
3	PDSS1	prenyl (decaprenyl) diphosphate synthase, subunit 1	11.0	Disorders
4	PIGA	phosphatidylinositol glycan anchor biosynthesis, class A	11.0
5	CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	11.0	Publications
6	BLM	Bloom syndrome, RecQ helicase-like	11.0
7	HBB	hemoglobin, beta	11.0	Publications

Compounds related to splenic infarction according to GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	neomycin32	9.3	CEACAM5, HBB
2	azathioprine32 34 9 9	12.3	APOH, HBB
3	n-acetylglucosamine32	9.2	CEACAM5, PIGA
4	hydroxyurea32 9 9	11.1	BLM, HBB
5	lactate32	9.0	CEACAM5, APOH, HBB