MCID: SPL006
MIFTS: 34

Splenic Infarction

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Splenic Infarction

MalaCards integrated aliases for Splenic Infarction:

Name: Splenic Infarction 12 51 41 14 69
Infarct of the Spleen 49
Splenic Infarcts 49
Splenic Infarct 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2533
ICD10 32 D73.5
MeSH 41 D013159
UMLS 69 C0037998

Summaries for Splenic Infarction

MalaCards based summary : Splenic Infarction, also known as infarct of the spleen, is related to endocarditis and infective endocarditis. An important gene associated with Splenic Infarction is HBB (Hemoglobin Subunit Beta). The drug Liver Extracts has been mentioned in the context of this disorder. Affiliated tissues include spleen, liver and myeloid.

Wikipedia : 72 Splenic infarction is a condition in which oxygen supply to the spleen is interrupted, leading to... more...

Related Diseases for Splenic Infarction

Diseases related to Splenic Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 149)
# Related Disease Score Top Affiliating Genes
1 endocarditis 30.2 APOH F2
2 infective endocarditis 30.1 APOH F2
3 thrombosis 29.9 APOH F2
4 thrombophilia due to thrombin defect 29.9 APOH F2
5 antiphospholipid syndrome 29.8 APOH F2
6 sickle cell anemia 29.7 F2 HBB
7 portal vein thrombosis 29.6 APOH F2
8 pulmonary embolism 29.4 APOH F2
9 purpura 29.2 APOH F2
10 hemoglobin e disease 10.2 F2 HBB
11 splenic disease 10.2 F2 HBB
12 spinal cord infarction 10.2 APOH F2
13 livedoid vasculopathy 10.2 APOH F2
14 cerebral sinovenous thrombosis 10.2 APOH F2
15 prothrombin deficiency, congenital 10.2 APOH F2
16 ischemic colitis 10.2 APOH F2
17 papilledema 10.2 APOH F2
18 sneddon syndrome 10.2 APOH F2
19 retinal artery occlusion 10.2 APOH F2
20 retinal vascular occlusion 10.2 APOH F2
21 buerger disease 10.2 APOH F2
22 hepatic infarction 10.2 APOH F2
23 prothrombin deficiency 10.2 APOH F2
24 thrombophlebitis 10.2 APOH F2
25 antithrombin iii deficiency 10.2 APOH F2
26 peripheral vertigo 10.2 APOH F2
27 central retinal vein occlusion 10.2 APOH F2
28 branch retinal artery occlusion 10.1 APOH F2
29 protein s deficiency 10.1 APOH F2
30 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 10.1
31 pancreatitis 10.1
32 placental abruption 10.1 APOH F2
33 ischemic optic neuropathy 10.1 APOH F2
34 malaria 10.1
35 intracranial hypertension 10.1 APOH F2
36 intermittent claudication 10.1 APOH F2
37 retinal vein occlusion 10.1 APOH F2
38 thrombophilia due to activated protein c resistance 10.1 APOH F2
39 budd-chiari syndrome 10.1 APOH F2
40 episodic pain syndrome, familial, 1 10.0
41 hereditary spherocytosis 10.0
42 aneurysm 10.0
43 hepatitis 9.9
44 leukemia 9.9
45 acute pancreatitis 9.9
46 patent foramen ovale 9.9 APOH F2
47 immune system disease 9.9 APOH F2 HBB
48 anemia, autoimmune hemolytic 9.9
49 polycythemia vera 9.9
50 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.9

Graphical network of the top 20 diseases related to Splenic Infarction:



Diseases related to Splenic Infarction

Symptoms & Phenotypes for Splenic Infarction

Drugs & Therapeutics for Splenic Infarction

Drugs for Splenic Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism Unknown status NCT02261584

Search NIH Clinical Center for Splenic Infarction

Cochrane evidence based reviews: splenic infarction

Genetic Tests for Splenic Infarction

Anatomical Context for Splenic Infarction

MalaCards organs/tissues related to Splenic Infarction:

38
Spleen, Liver, Myeloid, B Cells

Publications for Splenic Infarction

Articles related to Splenic Infarction:

(show top 50) (show all 307)
# Title Authors Year
1
Lessons learned from splenic infarcts with fever of unknown origin (FUO): culture-negative endocarditis (CNE) or malignancy? ( 29417312 )
2018
2
Streptococcus agalactiae infective endocarditis complicated by multiple mycotic hepatic aneurysms and massive splenic infarction: a case report. ( 29284415 )
2017
3
Pulmonary arteriovenous malformations complicated by splenic infarction and abscess. ( 28736615 )
2017
4
Splenic infarction associated with acute infectious mononucleosis. ( 28480876 )
2017
5
Transient antiphospholipid syndrome and splenic infarction in a patient with parvovirus B19 acute infection. ( 28602215 )
2017
6
Splenic Infarction in Two Members of the Family with Sickle Cell Trait: A Case Report of Rare Complication. ( 29308370 )
2017
7
Splenic Infarction as a Delayed Febrile Complication Following Radical Gastrectomy for Gastric Cancer Patients: Computed Tomography-Based Analysis. ( 29270657 )
2017
8
Splenic infarction due a common infection. ( 29078991 )
2017
9
A case of cytomegalovirus infection with splenic infarction and an esophageal ulcer in an immunocompetent adult. ( 28679983 )
2017
10
Long-term follow up of a massive, conservatively treated, splenic infarction in a young adolescent. ( 29044906 )
2017
11
Ischemic Necrosis of the Gastric Remnant without Splenic Infarction Following Subtotal Gastrectomy. ( 28835094 )
2017
12
Image Diagnosis: Splenic Infarction Associated with Oral Contraceptive Pills in a Healthy Young Woman. ( 28488992 )
2017
13
Splenic Infarction as Starting Symptom in Minimal Change Nephropathy. ( 28229998 )
2017
14
Acute Pancreatitis with Splenic Infarction as Early Postoperative Complication following Laparoscopic Sleeve Gastrectomy. ( 28487807 )
2017
15
Splenic Infarction and Rupture Due to Melioidosis. ( 29208262 )
2017
16
AN UNUSUAL CAUSE OF ACUTE ABDOMEN: SPLENIC INFARCTION. ( 29340557 )
2017
17
Spontaneous Splenic Infarcts in a Cirrhotic Patient with Primary Biliary Cirrhosis. ( 28203139 )
2017
18
Splenic Infarction in Acute Infectious Mononucleosis. ( 26602427 )
2016
19
Group B Streptococcal Tricuspid Valve Endocarditis with Splenic Infarction after an Elective Abortion. ( 27617630 )
2016
20
Splenic infarction associated with acute infectious mononucleosis due to Epstein-Barr virus infection. ( 27357912 )
2016
21
A Case of Isolated Celiac Artery Dissection Accompanied by Splenic Infarction Detected by Ultrasonography in the Emergency Department. ( 27148460 )
2016
22
Splenic infarction as a pitfall on labeled red blood cell imaging. ( 26917904 )
2016
23
Massive splenic infarction and splenic venous thrombosis observed in a patient with acute splenic syndrome of sickle cell traits on contrast-enhanced thin-slice computed tomography. ( 27251735 )
2016
24
Sequential Insults: Acute Lyme Disease with Splenic Infarction. ( 26688425 )
2016
25
A Diagnostic Pitfall: Salmonella Splenic Infarction in Hereditary Spherocytosis. ( 26272774 )
2015
26
An adolescent with hereditary spherocytosis who presented with splenic infarction. ( 26139647 )
2015
27
Splenic infarction and G-CSF. ( 26840787 )
2015
28
The unexpected finding of a splenic infarction in a patient with infectious mononucleosis due to Epstein-Barr virus. ( 26607191 )
2015
29
Acute Splenic Infarction at an Academic General Hospital Over 10 Years: Presentation, Etiology, and Outcome. ( 26356690 )
2015
30
Brachial artery mycotic aneurysm and splenic infarction associated with infective endocarditis. ( 26186921 )
2015
31
Mycosis fungoides associated with splenic infarction and muscle involvement. ( 25994394 )
2015
32
Splenic Infarction in Polycythemia Vera: Can the Spleen be Saved? ( 26731841 )
2015
33
Evaluation with contrast ultrasound of the prevalence of splenic infarction in left-sided infective endocarditis. ( 26261464 )
2015
34
Incidentally Discovered Splenic Infarction Associated with Scrub Typhus. ( 26333728 )
2015
35
Splenic infarction after reversal of warfarin using Prothrombinex-VF in a patient with a mechanical aortic valve. ( 26224191 )
2015
36
Dangerous proximity: splenic infarction after abdominal abscess. ( 25448176 )
2015
37
Splenic infarction - A rare cause of acute abdominal pain following gastric surgery: A case series. ( 25818369 )
2015
38
Splenic infarction associated with sickle cell trait at low altitude. ( 26133225 )
2015
39
The sonographic "bright band sign" of splenic infarction. ( 24866600 )
2014
40
Splenic infarction due to disseminated primary CMV infection. ( 25159098 )
2014
41
Splenic infarction in polycythaemia vera: can the spleen be saved? ( 25327078 )
2014
42
Massive splenic infarction and portal vein thrombosis in children with chronic myeloid leukemia. ( 24942025 )
2014
43
Splenic infarction caused by a rare coinfection of Epstein-Barr virus, cytomegalovirus, and Mycoplasma pneumoniae. ( 25186505 )
2014
44
Splenic infarction in Plasmodium vivax malaria. ( 24825280 )
2014
45
A novel frameshift mutation in exon 4 causing a deficiency of high-molecular-weight kininogen in a patient with splenic infarction. ( 24492696 )
2014
46
Spontaneous massive splenic infarction in the setting of renal transplant and septic shock: a case report and review of the literature. ( 25317176 )
2014
47
Splenic infarction and malaria. ( 24942899 )
2014
48
Massive splenic infarction leading to sickle cell disease. ( 25075666 )
2014
49
Conservative treatment of splenic infarction and intestinal obstruction caused by a wandering spleen. ( 24700108 )
2014
50
Asymptomatic partial splenic infarction in laparoscopic floppy nissen fundoplication and brief literature review. ( 24833155 )
2014

Variations for Splenic Infarction

Expression for Splenic Infarction

Search GEO for disease gene expression data for Splenic Infarction.

Pathways for Splenic Infarction

GO Terms for Splenic Infarction

Biological processes related to Splenic Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of blood coagulation GO:0030193 9.26 APOH F2
2 blood coagulation, intrinsic pathway GO:0007597 9.16 APOH F2
3 positive regulation of blood coagulation GO:0030194 8.96 APOH F2
4 negative regulation of fibrinolysis GO:0051918 8.62 APOH F2

Sources for Splenic Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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