MCID: SPL006
MIFTS: 43

Splenic Infarction malady

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Splenic Infarction

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Aliases & Descriptions for Splenic Infarction:

Name: Splenic Infarction 10 47 12 36 65
Infarct of the Spleen 45
 
Splenic Infarcts 45
Splenic Infarct 10

Classifications:



External Ids:

Disease Ontology10 DOID:2533
ICD1027 D73.5
MeSH36 D013159
UMLS65 C0037998

Summaries for Splenic Infarction

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Wikipedia:68 In medicine, splenic infarction is a condition in which oxygen supply to the spleen is interrupted,... more...

MalaCards based summary: Splenic Infarction, also known as infarct of the spleen, is related to malaria and pancreatitis. An important gene associated with Splenic Infarction is HBB (Hemoglobin Subunit Beta), and among its related pathways are Fat digestion and absorption and Pancreatic secretion. Affiliated tissues include spleen, lung and thyroid.

Related Diseases for Splenic Infarction

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Graphical network of the top 20 diseases related to Splenic Infarction:



Diseases related to splenic infarction

Symptoms for Splenic Infarction

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Drugs & Therapeutics for Splenic Infarction

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Drugs for Splenic Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Peginterferon alfa-2bapprovedPhase 329999210-65-8
Synonyms:
215647-85-1
D02748
PEG-Intron
PegIntron
Peginterferon alfa-2b
 
Peginterferon alfa-2b (INN)
Peginterferon alfa-2b (generical recombination)
Peginterferon alfa-2b (generical recombination) (JAN)
Pegintron
Pegintron (TN)
Sylatron
Unitron PEG
2interferonsPhase 31930
3Interferon-alphaPhase 31028
4Immunologic FactorsPhase 318483
5Antiviral AgentsPhase 3, Phase 28071
6Anti-Infective AgentsPhase 3, Phase 217220
7prolineNutraceuticalPhase 322
8Anti-Retroviral AgentsPhase 22794
9JM 3100Phase 2125
10
Mannitolapproved, investigationalPhase 124269-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
11Natriuretic AgentsPhase 11403
12diureticsPhase 11194
13Liver Extracts3572

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Vera PatientsCompletedNCT02523638Phase 3
2AOP2014 in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.RecruitingNCT02218047Phase 3
3AMD3100 to Mobilize Stem Cells for DonationCompletedNCT00075335Phase 2
4Phase I Clinical Safety Study About Human Umbilical Cord Blood Monocyte in the Acute Ischemic StrokeRecruitingNCT02433509Phase 1
5The Spleen in Sickle Cell Anemia and Sickle Cell ThalassemiaCompletedNCT00971698
6Microwave Ablation and Partial Splenic Embolization in the Management of HypersplenismRecruitingNCT02261584
7Immunological Profile in Relation to Cardiac Geometry in HypertensionRecruitingNCT02165241

Search NIH Clinical Center for Splenic Infarction


Cochrane evidence based reviews: splenic infarction

Genetic Tests for Splenic Infarction

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Anatomical Context for Splenic Infarction

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MalaCards organs/tissues related to Splenic Infarction:

33
Spleen, Lung, Thyroid, Monocytes, Endothelial, Liver, Myeloid

Animal Models for Splenic Infarction or affiliated genes

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Publications for Splenic Infarction

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Articles related to Splenic Infarction:

(show top 50)    (show all 287)
idTitleAuthorsYear
1
Splenic Infarction in Polycythemia Vera: Can the Spleen be Saved? (26731841)
2015
2
Splenic infarction and malaria. (24942899)
2014
3
Spontaneous massive splenic infarction in the setting of renal transplant and septic shock: a case report and review of the literature. (25317176)
2014
4
Splenic infarction in polycythaemia vera: can the spleen be saved? (25327078)
2014
5
Splenic infarction in P.vivax malaria. (24096848)
2013
6
Splenic infarction as a rare complication of infectious mononucleosis due to Epstein-Barr virus infection in a patient with no significant comorbidity: case report and review of the literature. (23957538)
2013
7
Splenic infarction, warm autoimmune hemolytic anemia and antiphospholipid antibodies associated with systemic lupus erythematosus. (22623174)
2012
8
Plasmodium vivax malaria complicated by splenic infarct. (24090806)
2012
9
Sarcoidosis presenting as massive splenic infarction. (22953152)
2012
10
A 53-year-old female with a 3- to 4-month history of fever, night sweats, lethargy, anorexia, splenic infarction, and worsening mitral valve prolapse. (22345584)
2012
11
Spontaneous splenic infarction in an elderly cirrhotic patient with multiple comorbidities. (23161308)
2012
12
Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient. (21246003)
2011
13
Splenic infarction associated with rapidly progressive chronic lymphocytic leukemia with complex karyotype and ATM mutation. (21185599)
2011
14
Acute massive splenic infarction with complete liquefaction of the spleen in sickle cell disease. (21982890)
2011
15
Splenic infarction: rare complication of N-butyl-2-cyanoacrylate injection for gastric varices. (20078672)
2010
16
Splenic infarcts in chronic hepatopathy accompanied by cryoglobulinemia: two case reports. (20190728)
2010
17
Splenic infarct is a plausible alternative diagnosis in suspected splenic abscess. (20122618)
2010
18
Abdominal pain increasing during hemodialysis session, do not miss splenic infarction. (21105993)
2010
19
A case of lymphoma presenting as splenic infarction. (21686600)
2009
20
Splenic infarction: a rare cause of acute abdominal pain presenting in an older patient with primary antiphospholipid antibodies syndrome. (19701683)
2009
21
Splenic infarction and abscess after endoscopic injection of hypertonic saline-epinephrine solution administered for bleeding gastric ulcer. (18991218)
2008
22
Splenic infarction complicated by splenic artery occlusion after N-butyl-2-cyanoacrylate injection for gastric varices: case report. (15729263)
2005
23
Splenic infarction in a pregnant woman with systemic lupus erythematosus. (15714383)
2005
24
Case report: polycythaemia vera presenting as massive splenic infarction and liquefaction. (15483002)
2004
25
CT diagnosis of splenic infarction in blunt trauma: imaging features, clinical significance and complications. (15041453)
2004
26
Primary antiphospholipid syndrome presenting with abdominal angina and splenic infarction. (12111088)
2002
27
The elderly haemodialysis patient with abdominal symptoms and hypovolemic shock--splenic rupture secondary to splenic infarction in a patient with severe atherosclerosis. (10328514)
1999
28
Q-fever associated with splenic infarction and an anti-cardiolipin antibody. (10630667)
1999
29
Splenic infarction caused by idiopathic venous thrombosis. (10228446)
1998
30
Systemic mast cell disease with splenic infarction: a case report. (9704348)
1998
31
Splenic infarction caused by a large thoracic aortic thrombus. (9423725)
1997
32
Splenic infarction in a child with portal hypertension secondary to biliary atresia. (9126779)
1997
33
Splenic infarction: report of three cases of atherosclerotic embolization originating in the aorta and retrospective study of 64 cases. (8997756)
1996
34
Total splenic infarction in acute pancreatitis. (8930045)
1996
35
Splenic infarction from cholesterol embolization following cardiopulmonary bypass. (8745180)
1995
36
Splenic infarction in 16 dogs: a retrospective study. (7674215)
1995
37
Splenic infarction after splenorenal arterial bypass. (8445759)
1993
38
Splenic infarction. Detection by In-111 leukocyte scintigraphy. (1424364)
1992
39
Functional deficiency of protein C associated with mesenteric venous thrombosis and splenic infarction. (2069226)
1991
40
CT scan of the abdomen in the evaluation of splenic infarction. (2308313)
1990
41
Pulmonary embolism and splenic infarction in a patient with sickle cell trait. (2316514)
1990
42
Non-altitude-related splenic infarction in a patient with sickle cell trait. (2686437)
1989
43
Sickle cell trait in a white Jewish family presenting as splenic infarction at high altitude. (3354556)
1988
44
CT patterns of splenic infarction: a clinical and experimental study. (6718733)
1984
45
Splenic infarct associated with diaphragmatic eventration: case report illustrating the non-specificity of splenic focal defects. (709983)
1978
46
Massive splenic infarction in cirrhosis: report of a case with spontaneous disappearance of hypersplenism. (1084843)
1976
47
Howell-Jolly bodies. A clue to splenic infarction. (1130931)
1975
48
Letter: Splenic infarction in sickle-cell trait: are whites more susceptible? (4852932)
1974
49
Splenic infarction diagnosed by photoscanning. (5033915)
1972
50
Sickle-cell trait and splenic infarction associated with high-altitude flying. (13194086)
1954

Variations for Splenic Infarction

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Expression for genes affiliated with Splenic Infarction

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Search GEO for disease gene expression data for Splenic Infarction.

Pathways for genes affiliated with Splenic Infarction

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Pathways related to Splenic Infarction according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.6PLA2G2A, PLA2G2D
29.6PLA2G2A, PLA2G2D
39.4PLA2G2A, PLA2G4A
49.4PLA2G2A, PLA2G4A
5
Show member pathways
9.4PLA2G2A, PLA2G4A
6
Show member pathways
9.4PLA2G2A, PLA2G4A
7
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
8
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
9
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
10
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
11
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
12
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
13
Show member pathways
8.5IFNA2, PLA2G2A, PLA2G2D, PLA2G4A
14
Show member pathways
7.3ABCB1, HBB, PLA2G2A, PLA2G2D, PLA2G4A, REV3L

GO Terms for genes affiliated with Splenic Infarction

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Biological processes related to Splenic Infarction according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1phosphatidylethanolamine acyl-chain remodelingGO:003615210.0PLA2G2A, PLA2G4A
2lipid catabolic processGO:00160429.9PLA2G2A, PLA2G2D
3glycerophospholipid biosynthetic processGO:00464749.7PLA2G2D, PLA2G4A
4response to hydrogen peroxideGO:00425429.7HBB, PLA2G4A
5phosphatidic acid biosynthetic processGO:00066549.6PLA2G2D, PLA2G4A
6phosphatidylinositol acyl-chain remodelingGO:00361499.5PLA2G2A, PLA2G2D, PLA2G4A
7positive regulation of inflammatory responseGO:00507299.4PLA2G2A, PLA2G4A
8phospholipid metabolic processGO:00066448.9PLA2G2A, PLA2G2D, PLA2G4A

Sources for Splenic Infarction

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet