MCID: SPL006
MIFTS: 38

Splenic Infarction malady

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Splenic Infarction

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Aliases & Descriptions for Splenic Infarction:

Name: Splenic Infarction 10 47 12 36 65
Infarct of the Spleen 45
 
Splenic Infarcts 45
Splenic Infarct 10

Classifications:



External Ids:

Disease Ontology10 DOID:2533
ICD1027 D73.5
MeSH36 D013159
UMLS65 C0037998

Summaries for Splenic Infarction

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Wikipedia:68 In medicine, splenic infarction is a condition in which oxygen supply to the spleen is interrupted,... more...

MalaCards based summary: Splenic Infarction, also known as infarct of the spleen, is related to breast cancer and hepatitis. An important gene associated with Splenic Infarction is HBB (Hemoglobin Subunit Beta), and among its related pathways are Fat digestion and absorption and Pancreatic secretion. Affiliated tissues include spleen, lung and monocytes.

Related Diseases for Splenic Infarction

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Graphical network of the top 20 diseases related to Splenic Infarction:



Diseases related to splenic infarction

Symptoms for Splenic Infarction

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Drugs & Therapeutics for Splenic Infarction

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Drugs for Splenic Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Peginterferon alfa-2bapprovedPhase 329999210-65-8
Synonyms:
215647-85-1
D02748
PEG-Intron
PegIntron
Peginterferon alfa-2b
 
Peginterferon alfa-2b (INN)
Peginterferon alfa-2b (generical recombination)
Peginterferon alfa-2b (generical recombination) (JAN)
Pegintron
Pegintron (TN)
Sylatron
Unitron PEG
2interferonsPhase 31930
3Interferon-alphaPhase 31028
4Immunologic FactorsPhase 318483
5Antiviral AgentsPhase 3, Phase 28071
6Anti-Infective AgentsPhase 3, Phase 217220
7prolineNutraceuticalPhase 322
8Anti-Retroviral AgentsPhase 22794
9JM 3100Phase 2125
10
Mannitolapproved, investigationalPhase 124269-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
11Natriuretic AgentsPhase 11403
12diureticsPhase 11194
13Liver Extracts3572

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Vera PatientsCompletedNCT02523638Phase 3
2AOP2014 in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.RecruitingNCT02218047Phase 3
3AMD3100 to Mobilize Stem Cells for DonationCompletedNCT00075335Phase 2
4Phase I Clinical Safety Study About Human Umbilical Cord Blood Monocyte in the Acute Ischemic StrokeRecruitingNCT02433509Phase 1
5The Spleen in Sickle Cell Anemia and Sickle Cell ThalassemiaCompletedNCT00971698
6Microwave Ablation and Partial Splenic Embolization in the Management of HypersplenismRecruitingNCT02261584
7Immunological Profile in Relation to Cardiac Geometry in HypertensionRecruitingNCT02165241

Search NIH Clinical Center for Splenic Infarction


Cochrane evidence based reviews: splenic infarction

Genetic Tests for Splenic Infarction

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Anatomical Context for Splenic Infarction

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MalaCards organs/tissues related to Splenic Infarction:

33
Spleen, Lung, Monocytes, Bone, Breast, Endothelial, T cells

Animal Models for Splenic Infarction or affiliated genes

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Publications for Splenic Infarction

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Articles related to Splenic Infarction:

(show top 50)    (show all 274)
idTitleAuthorsYear
1
High-level quinolone resistance is associated with the overexpression of smeVWX in Stenotrophomonas maltophilia clinical isolates. (25753190)
2015
2
Downregulation of urinary cell-free microRNA-214 as a diagnostic and prognostic biomarker in bladder cancer. (25975233)
2015
3
Significance of soluble lectin-like oxidized LDL receptor-1 levels in systemic and coronary circulation in acute coronary syndrome. (24895597)
2014
4
Family association study between tumour necrosis factor a gene polymorphisms and polycystic ovary syndrome in Han Chinese. (25246119)
2014
5
Control of soil-transmitted helminthiasis in Yunnan province, People's Republic of China: experiences and lessons from a 5-year multi-intervention trial. (25308524)
2014
6
Polyunsaturated omega-3 fatty acids reduce lipoprotein-associated phospholipase A(2) in patients with stable angina. (24555913)
2014
7
Underlying cause and place of death among patients with amyotrophic lateral sclerosis in Taiwan: a population-based study, 2003-2008. (23933623)
2013
8
The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy. (23562826)
2013
9
Increased expression of Trop2 correlates with poor survival in extranodal NK/T cell lymphoma, nasal type. (23979406)
2013
10
Hyperglycemia within day 14 of aneurysmal subarachnoid hemorrhage predicts 1-year mortality. (23072944)
2013
11
Genome-wide association analysis of age-at-onset in Alzheimer's disease. (22005931)
2012
12
True left-sided gallbladder with a portal anomaly: report of a case. (22160358)
2012
13
Late-onset laryngomalacia: a cause of pediatric obstructive sleep apnea. (21115204)
2011
14
Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells. (20360620)
2010
15
Saphenous mononeuropathy after popliteal vein aneurysm repair. (20065798)
2010
16
COMT ValMet moderation of cannabis-induced psychosis: a momentary assessment study of 'switching on' hallucinations in the flow of daily life. (18808401)
2009
17
Diffuse pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: long-term results of embolization according to the extent of lung involvement. (19118276)
2009
18
Functional analysis of -351 interleukin-9 promoter polymorphism reveals an activator controlled by NF-kappaB. (19387455)
2009
19
Alcohol dehydrogenase type 1C (ADH1C) variants, alcohol consumption traits, HDL-cholesterol and risk of coronary heart disease in women and men: British Women's Heart and Health Study and Caerphilly cohorts. (17379229)
2008
20
Prototypical anti-inflammatory cytokine IL-10 prevents loss of IGF-I-induced myogenin protein expression caused by IL-1beta. (18270299)
2008
21
Budesonide/formoterol decreases expression of vascular endothelial growth factor (VEGF) and VEGF receptor 1 within airway remodelling in asthma. (18421428)
2008
22
Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult. (16473422)
2006
23
EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration. (16848764)
2006
24
Frasier syndrome: a rare syndrome with WT1 gene mutation in pediatric urology]. (16440249)
2006
25
Lack of protection of N-acetylcysteine (NAC) in acute renal failure related to elective aortic aneurysm repair-a randomized controlled trial. (16522657)
2006
26
Prevalence of the Factor V G1691A and the Factor II/prothrombin G20210A gene polymorphisms among Tamilians. (15896772)
2005
27
HRCT appearance of systemic mastocytosis involving the lungs. (14712134)
2004
28
Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. (12681357)
2003
29
Changes of serum growth factors (IGF-I,-II and IGFBP-2,-3) prior to and after stem cell transplantation in children with acute leukemia. (12900778)
2003
30
Study on interactions of endocrine disruptors with estrogen receptor-beta using fluorescence polarization. (12945660)
2003
31
A gene expression in study human gastric adenocarcinoma using a cDNA microarray. (14695705)
2003
32
Exophthalmos: a rare complication of systemic corticosteroids. (11989195)
2002
33
Pacemaker-induced superior vena cava syndrome: a case report and review of management strategy. (12464987)
2002
34
Angelman syndrome methylation screening of 15q11-q13 in institutionalized individuals with severe mental retardation. (12215253)
2002
35
Congenital toxoplasmosis. (12230689)
2002
36
Negative regulation of adipose-expressed galectin-12 by isoproterenol, tumor necrosis factor alpha, insulin and dexamethasone. (12370119)
2002
37
Stereotactic radiosurgery for acoustic neuroma: a Canadian perspective. (9827233)
1998
38
Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas. (9285563)
1997
39
Stromelysin-3: a paradigm for stroma-derived factors implicated in carcinoma progression. (9246540)
1997
40
Backbone dynamics of the c-Jun leucine zipper: 15N NMR relaxation studies. (8664278)
1996
41
Seeding of vascular grafts with genetically modified endothelial cells. Secretion of recombinant TPA results in decreased seeded cell retention in vitro and in vivo. (8641034)
1996
42
High prevalence of Ancylostoma spp. infection in dogs, associated with endemic focus of human cutaneous larva migrans, in Tacuarembo, Uruguay. (8758550)
1996
43
Chest tubes, lung entrapment, and failure to wean from the ventilator. Report of three patients with quadriplegia. (8162779)
1994
44
Regulation of neutrophil interleukin 8 gene expression and protein secretion by LPS, TNF-alpha, and IL-1 beta. (8436597)
1993
45
Rapid aggravation of splenomegaly by administration of erythropoietin in a case of myelodysplastic syndrome]. (1479699)
1992
46
Cystic adrenal masses in the neonate associated with hemihypertrophy and the relation to the Beckwith-Wiedemann syndrome. (1861304)
1991
47
Early relapse of acute inflammatory polyradiculoneuropathy after successful treatment with plasma exchange. (3389077)
1988
48
CT in cerebral thrombophlebitis. (3990947)
1985
49
Diagnosis of asbestosis. Clinical, radiological and lung function data in 42 patients. (6527564)
1984
50
Caries of Frontal Bone and Intracranial Abscess due to Bacillus typhosus Eleven Years after Attack of Typhoid Fever. (19976388)
1912

Variations for Splenic Infarction

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Expression for genes affiliated with Splenic Infarction

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Search GEO for disease gene expression data for Splenic Infarction.

Pathways for genes affiliated with Splenic Infarction

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Pathways related to Splenic Infarction according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.6PLA2G2A, PLA2G2D
29.6PLA2G2A, PLA2G2D
39.4PLA2G2A, PLA2G4A
49.4PLA2G2A, PLA2G4A
5
Show member pathways
9.4PLA2G2A, PLA2G4A
6
Show member pathways
9.4PLA2G2A, PLA2G4A
7
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
8
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
9
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
10
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
11
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
12
Show member pathways
9.0PLA2G2A, PLA2G2D, PLA2G4A
13
Show member pathways
8.5IFNA2, PLA2G2A, PLA2G2D, PLA2G4A
14
Show member pathways
7.3ABCB1, HBB, PLA2G2A, PLA2G2D, PLA2G4A, REV3L

GO Terms for genes affiliated with Splenic Infarction

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Biological processes related to Splenic Infarction according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1phosphatidylethanolamine acyl-chain remodelingGO:003615210.0PLA2G2A, PLA2G4A
2lipid catabolic processGO:00160429.9PLA2G2A, PLA2G2D
3glycerophospholipid biosynthetic processGO:00464749.7PLA2G2D, PLA2G4A
4response to hydrogen peroxideGO:00425429.7HBB, PLA2G4A
5phosphatidic acid biosynthetic processGO:00066549.6PLA2G2D, PLA2G4A
6phosphatidylinositol acyl-chain remodelingGO:00361499.5PLA2G2A, PLA2G2D, PLA2G4A
7positive regulation of inflammatory responseGO:00507299.4PLA2G2A, PLA2G4A
8phospholipid metabolic processGO:00066448.9PLA2G2A, PLA2G2D, PLA2G4A

Sources for Splenic Infarction

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet