MCID: SPL006
MIFTS: 35

Splenic Infarction malady

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Splenic Infarction

Aliases & Descriptions for Splenic Infarction:

Name: Splenic Infarction 12 52 42 14 69
Infarct of the Spleen 50
Splenic Infarcts 50
Splenic Infarct 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2533
ICD10 33 D73.5
MeSH 42 D013159
UMLS 69 C0037998

Summaries for Splenic Infarction

MalaCards based summary : Splenic Infarction, also known as infarct of the spleen, is related to oxyphilic adenoma and chronic inflammatory demyelinating polyneuritis. An important gene associated with Splenic Infarction is HBB (Hemoglobin Subunit Beta). The drugs Peginterferon alfa-2b and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include spleen, liver and myeloid.

Wikipedia : 71 Splenic infarction is a condition in which oxygen supply to the spleen is interrupted, leading to... more...

Related Diseases for Splenic Infarction

Diseases related to Splenic Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
id Related Disease Score Top Affiliating Genes
1 oxyphilic adenoma 10.2 F2 HBB
2 chronic inflammatory demyelinating polyneuritis 10.2 F2 HBB
3 vascular erectile tumor 10.2 APOH F2
4 lubinsky syndrome 10.2 APOH F2
5 supraumbilical midabdominal raphe and facial cavernous hemangiomas 10.2 APOH F2
6 hendra virus infection 10.2 APOH F2
7 may-hegglin anomaly 10.2 APOH F2
8 left-right axis malformations 10.2 APOH F2
9 lymphocytic colitis 10.2 APOH F2
10 prostatitis 10.2 APOH F2
11 spinal cord lipoma 10.2 APOH F2
12 bullous skin disease 10.1 APOH F2
13 glutathionuria 10.1 APOH F2
14 lynch syndrome 10.1 APOH F2
15 cryptosporidiosis 10.1 APOH F2
16 angular blepharoconjunctivitis 10.1 APOH F2
17 blepharoconjunctivitis 10.1 APOH F2
18 intestinal disaccharidase deficiency 10.1 APOH F2
19 dysgammaglobulinemia 10.1 APOH F2
20 ophthalmia neonatorum 10.1 APOH F2
21 autoimmune disease of central nervous system 10.1 APOH F2
22 central retinal artery occlusion 10.1 APOH F2
23 pregnancy loss, recurrent 2 10.1 APOH F2
24 ischemic optic neuropathy 10.1 APOH F2
25 scar contracture 10.1 APOH F2
26 uterine corpus cancer 10.1 APOH F2
27 pregnancy loss, recurrent 1 10.1 APOH F2
28 thrombophilia due to activated protein c resistance 10.1 APOH F2
29 fetal hemoglobin quantitative trait locus 1 10.1 F2 HBB
30 immunodeficiency, common variable, 6 10.1 APOH F2
31 sertoli-leydig cell tumor 10.1 APOH F2
32 leukocyte disease 10.1 APOH F2
33 asbestosis 10.1 APOH F2
34 haemonchiasis 10.1 APOH F2
35 thrombosis 10.0
36 bone development disease 10.0 APOH F2
37 malaria 10.0
38 pancreatitis 10.0
39 dentine erosion 10.0 APOH F2
40 obstructive jaundice 10.0 APOH F2
41 membranoproliferative glomerulonephritis 10.0 APOH F2
42 giant papillary conjunctivitis 10.0 APOH F2
43 endocarditis 10.0
44 hereditary spherocytosis 9.9
45 acute proliferative glomerulonephritis 9.9 APOH F2
46 leukemia 9.9
47 aneurysm 9.9
48 acute pancreatitis 9.8
49 infective endocarditis 9.8
50 autoimmune hemolytic anemia 9.8

Graphical network of the top 20 diseases related to Splenic Infarction:



Diseases related to Splenic Infarction

Symptoms & Phenotypes for Splenic Infarction

Drugs & Therapeutics for Splenic Infarction

Drugs for Splenic Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Peginterferon alfa-2b Approved Phase 3 99210-65-8, 215647-85-1
2 Anti-Infective Agents Phase 3,Phase 2
3 Antiviral Agents Phase 3,Phase 2
4 Interferon-alpha Phase 3
5 interferons Phase 3
6 proline Nutraceutical Phase 3
7 Anti-HIV Agents Phase 2
8 Anti-Retroviral Agents Phase 2
9 JM 3100 Phase 2
10
Mannitol Approved, Investigational Phase 1 69-65-8 453 6251
11 diuretics Phase 1
12 Natriuretic Agents Phase 1
13 Liver Extracts

Interventional clinical trials:


id Name Status NCT ID Phase
1 Study to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Vera Patients Completed NCT02523638 Phase 3
2 AOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study. Active, not recruiting NCT02218047 Phase 3
3 AMD3100 to Mobilize Stem Cells for Donation Completed NCT00075335 Phase 2
4 Phase I Clinical Safety Study About Human Umbilical Cord Blood Monocyte in the Acute Ischemic Stroke Recruiting NCT02433509 Phase 1
5 Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism Unknown status NCT02261584
6 The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia Completed NCT00971698
7 Immunological Profile in Relation to Cardiac Geometry in Hypertension Completed NCT02165241

Search NIH Clinical Center for Splenic Infarction

Cochrane evidence based reviews: splenic infarction

Genetic Tests for Splenic Infarction

Anatomical Context for Splenic Infarction

MalaCards organs/tissues related to Splenic Infarction:

39
Spleen, Liver, Myeloid, B Cells

Publications for Splenic Infarction

Articles related to Splenic Infarction:

(show top 50) (show all 290)
id Title Authors Year
1
A Case of Isolated Celiac Artery Dissection Accompanied by Splenic Infarction Detected by Ultrasonography in the Emergency Department. ( 27148460 )
2016
2
Splenic infarction as a pitfall on labeled red blood cell imaging. ( 26917904 )
2016
3
Sequential Insults: Acute Lyme Disease with Splenic Infarction. ( 26688425 )
2016
4
Splenic infarction associated with acute infectious mononucleosis due to Epstein-Barr virus infection. ( 27357912 )
2016
5
Splenic Infarction in Acute Infectious Mononucleosis. ( 26602427 )
2016
6
Group B Streptococcal Tricuspid Valve Endocarditis with Splenic Infarction after an Elective Abortion. ( 27617630 )
2016
7
Massive splenic infarction and splenic venous thrombosis observed in a patient with acute splenic syndrome of sickle cell traits on contrast-enhanced thin-slice computed tomography. ( 27251735 )
2016
8
Splenic Infarction in Polycythemia Vera: Can the Spleen be Saved? ( 26731841 )
2015
9
The unexpected finding of a splenic infarction in a patient with infectious mononucleosis due to Epstein-Barr virus. ( 26607191 )
2015
10
An adolescent with hereditary spherocytosis who presented with splenic infarction. ( 26139647 )
2015
11
Dangerous proximity: splenic infarction after abdominal abscess. ( 25448176 )
2015
12
A Diagnostic Pitfall: Salmonella Splenic Infarction in Hereditary Spherocytosis. ( 26272774 )
2015
13
Brachial artery mycotic aneurysm and splenic infarction associated with infective endocarditis. ( 26186921 )
2015
14
Acute Splenic Infarction at an Academic General Hospital Over 10 Years: Presentation, Etiology, and Outcome. ( 26356690 )
2015
15
Splenic infarction after reversal of warfarin using Prothrombinex-VF in a patient with a mechanical aortic valve. ( 26224191 )
2015
16
Mycosis fungoides associated with splenic infarction and muscle involvement. ( 25994394 )
2015
17
Evaluation with contrast ultrasound of the prevalence of splenic infarction in left-sided infective endocarditis. ( 26261464 )
2015
18
Incidentally Discovered Splenic Infarction Associated with Scrub Typhus. ( 26333728 )
2015
19
Splenic infarction - A rare cause of acute abdominal pain following gastric surgery: A case series. ( 25818369 )
2015
20
Splenic infarction and G-CSF. ( 26840787 )
2015
21
Splenic infarction associated with sickle cell trait at low altitude. ( 26133225 )
2015
22
Splenic infarction in polycythaemia vera: can the spleen be saved? ( 25327078 )
2014
23
A novel frameshift mutation in exon 4 causing a deficiency of high-molecular-weight kininogen in a patient with splenic infarction. ( 24492696 )
2014
24
The sonographic "bright band sign" of splenic infarction. ( 24866600 )
2014
25
Splenic infarction in Plasmodium vivax malaria. ( 24825280 )
2014
26
Malaria-Induced Splenic Infarction. ( 25294615 )
2014
27
Massive splenic infarction and portal vein thrombosis in children with chronic myeloid leukemia. ( 24942025 )
2014
28
Massive splenic infarction leading to sickle cell disease. ( 25075666 )
2014
29
Splenic infarction caused by a rare coinfection of Epstein-Barr virus, cytomegalovirus, and Mycoplasma pneumoniae. ( 25186505 )
2014
30
Asymptomatic partial splenic infarction in laparoscopic floppy nissen fundoplication and brief literature review. ( 24833155 )
2014
31
Spontaneous massive splenic infarction in the setting of renal transplant and septic shock: a case report and review of the literature. ( 25317176 )
2014
32
Splenic infarction and malaria. ( 24942899 )
2014
33
Conservative treatment of splenic infarction and intestinal obstruction caused by a wandering spleen. ( 24700108 )
2014
34
Splenic infarction due to disseminated primary CMV infection. ( 25159098 )
2014
35
A unique cause of intestinal and splenic infarction in a sickle cell trait patient. ( 23738181 )
2013
36
Splenic infarction in P.vivax malaria. ( 24096848 )
2013
37
Meningitis and splenic infarction due to disseminated Mycobacterium genavense infection in an HIV patient. Case report and review of the literature. ( 24156225 )
2013
38
Q Fever with transient antiphospholipid antibodies associated with cholecystitis and splenic infarction. ( 23271442 )
2013
39
Splenic infarction in a child with primary Epstein-Barr virus infection. ( 24134766 )
2013
40
Splenic infarction at high altitude secondary to sickle cell trait. ( 22944537 )
2013
41
Gastric remnant necrosis following splenic infarction after distal gastrectomy in a gastric cancer patient. ( 23702363 )
2013
42
Hepatic and splenic infarction and bowel ischemia following endoscopic ultrasound-guided celiac plexus neurolysis. ( 23767046 )
2013
43
Identification of splenic infarction by emergency department ultrasound. ( 22698828 )
2013
44
Acute abdomen due to splenic infarction as the initial presentation of pediatric acute lymphoblastic leukemia. ( 23386231 )
2013
45
A case of vivax malaria with splenic infarction. ( 23703446 )
2013
46
Spontaneous (atraumatic) splenic rupture complicating anticoagulant treatment for splenic infarction. ( 24187770 )
2013
47
Multiple splenic infarcts in acute Plasmodium vivax malaria: a rare case report. ( 23608386 )
2013
48
Splenic infarction after N-butyl-2-cyanoacrylate injection for gastric varices: why does it happen? ( 24105294 )
2013
49
Splenic infarction as a rare complication of infectious mononucleosis due to Epstein-Barr virus infection in a patient with no significant comorbidity: case report and review of the literature. ( 23957538 )
2013
50
Massive splenic infarction in an adolescent with hemoglobin S-HPFH. ( 23281181 )
2013

Variations for Splenic Infarction

Expression for Splenic Infarction

Search GEO for disease gene expression data for Splenic Infarction.

Pathways for Splenic Infarction

GO Terms for Splenic Infarction

Cellular components related to Splenic Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 APOH CPA1 F2 HBB

Biological processes related to Splenic Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of blood coagulation GO:0030193 9.26 APOH F2
2 blood coagulation, intrinsic pathway GO:0007597 9.16 APOH F2
3 positive regulation of blood coagulation GO:0030194 8.96 APOH F2
4 negative regulation of fibrinolysis GO:0051918 8.62 APOH F2

Sources for Splenic Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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