MCID: SPL009
MIFTS: 21

Splenic Sequestration malady

Immune diseases category
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Summaries for Splenic Sequestration

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33MalaCards
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MalaCards: Splenic Sequestration is related to sickle cell disease and sickle cell anemia. An important gene associated with Splenic Sequestration is GBA2 (glucosidase, beta (bile acid) 2). Related mouse phenotype immune system.

Aliases & Classifications for Splenic Sequestration

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8Disease Ontology, 10DISEASES, 62UMLS, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases


Aliases & Descriptions:

splenic sequestration 8 10 62


External Ids:

Disease Ontology8 DOID:11786
ICD9CM27 289.52

Related Diseases for Splenic Sequestration

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17GeneCards, 18GeneDecks
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Diseases related to Splenic Sequestration via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1sickle cell disease10.8
2sickle cell anemia10.6
3beta thalassemia10.4
4thalassemia10.4
5hemoglobin c disease10.4
6splenic infarction10.3
7hereditary spherocytosis10.3
8thrombocytopenia10.3
9hypersplenism10.2
10hepatitis10.2
11leukemia10.2
12splenomegaly10.2
13chronic lymphocytic leukemia10.1
14hemoglobinopathy10.1
15hemolytic anemia10.1
16peritonitis10.1
17sepsis10.1
18hemoglobin e - beta-thalassemia10.1

Graphical network of diseases related to Splenic Sequestration:



Diseases related to splenic sequestration

Symptoms for Splenic Sequestration

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Drugs & Therapeutics for Splenic Sequestration

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Splenic Sequestration

Genetic Tests for Splenic Sequestration

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Anatomical Context for Splenic Sequestration

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Animal Models for Splenic Sequestration or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Splenic Sequestration:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053879.1THPO, GBA2

Publications for Splenic Sequestration

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52PubMed
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Articles related to Splenic Sequestration:

(show top 50)    (show all 88)
idTitleAuthorsYear
1
Acute splenic sequestration in a pregnant woman with homozygous sickle-cell anemia. (23657515)
2013
2
Acute splenic sequestration crisis in sickle cell disease: cohort study of 190 paediatric patients. (22224796)
2012
3
Acute splenic sequestration crisis in an adult with sickle cell anaemia. (22411649)
2012
4
Elevated IL-1I+ and CXCL10 serum levels occur in patients with homozygous sickle cell disease and a history of acute splenic sequestration. (22674409)
2012
5
Partial Splenic Embolization as a Bridge to Total Knee Replacement for a Patient with Severe Thrombocytopenia due to Cirrhosis and Splenic Sequestration. (23304579)
2012
6
Relationship between splenic sequestration and thrombocytopenia in Trypanosoma evansi infection in rats. (21185577)
2011
7
Acute splenic sequestration in a cohort of children with sickle cell anemia. (19319450)
2009
8
Acute splenic sequestration in children with sickle cell anemia. (19668914)
2009
9
Simultaneous acute splenic sequestration and transient aplastic crisis in children with sickle cell disease. (19418550)
2009
10
Partial splenectomy prevents splenic sequestration crises in sickle cell disease. (19944213)
2009
11
Acute splenic sequestration crisis (ASSC) in an adult patient with beta-thalassemia sickle cell disease: a life-threatening complication. (18084762)
2008
12
Acute splenic sequestration in an adult with hemoglobin S-C disease. (19091280)
2008
13
Determination of hemolytic anemia through the study of (51)Cr red cell survival and splenic sequestration. (18483142)
2008
14
Acute splenic sequestration crisis in adults with sickle cell anemia. (16924644)
2007
15
Acute splenic sequestration crisis in adults with hemoglobin S-C disease: a report of nine cases. (16463155)
2006
16
Acute splenic sequestration crisis resembling sepsis in an adult with hemoglobin SC disease. (15108841)
2004
17
Intracranial hemorrhage associated with splenic sequestration in a Saudi child with sickle cell anemia: case report and review of the literature. (17264555)
2001
18
Laparoscopic splenectomy for splenic sequestration crisis. (10806537)
2000
19
Aplastic crisis and acute splenic sequestration crisis. (10779041)
2000
20
Case report: splenic sequestration and multiorgan failure as the presenting manifestation of hemoglobin SC disease. (8615389)
1996
21
Splenectomy and acute splenic sequestration crises in sickle cell disease. (24057466)
1996
22
Acute splenic sequestration in the absence of palpable splenomegaly. (8166373)
1994
23
Acute splenic sequestration together with aplastic crisis caused by human parvovirus B19 in patients with sickle cell disease. (8463907)
1993
24
A fatal case of acute splenic sequestration in a 53-year-old woman with sickle-hemoglobin C disease. (1731518)
1992
25
SPECT versus planar scintigraphy for quantification of splenic sequestration of 111In-labelled platelets. (1491841)
1992
26
Splenic sequestration associated with sickle cell trait and hereditary spherocytosis. (1585908)
1992
27
Acute splenic sequestration crisis in sickle cell disease: early detection and treatment. (1564621)
1992
28
Hematologic improvement in a patient with Gaucher disease on long-term enzyme replacement therapy: evidence for decreased splenic sequestration and improved red blood cell survival. (1951303)
1991
29
Acute splenic sequestration in Jamaican adults with homozygous sickle cell disease: a role of alpha thalassaemia. (2025582)
1991
30
Pulmonary, hepatic and splenic sequestration of technetium-99m labelled autologous rabbit granulocytes: scintigraphic cell distributions after intravenous and intraarterial injections, exsanguination and intraarterial injection of cells passed through an intermediary host. (1962525)
1991
31
Massive splenic infarction in doubly abnormal heterozygous sickling disorders. A new complication of acute splenic sequestration syndrome. (1815406)
1991
32
Management of acute splenic sequestration crisis in sickle cell disease. (2136619)
1990
33
Recurrent acute splenic sequestration crisis due to interacting genetic defects: hemoglobin SC disease and hereditary spherocytosis. (2294990)
1990
34
Acute splenic sequestration crisis in two adults with sickle cell disease: US, CT, and MR imaging findings. (2243976)
1990
35
Acute splenic sequestration crises in Saudi children with sickle cell disease. (2473699)
1989
36
Acute splenic sequestration in siblings with sickle cell disease. (2456724)
1988
37
Acute splenic sequestration in sickle cell disease. (3712147)
1986
38
Acute splenic sequestration crises in adults with sickle cell disease. (3706382)
1986
39
Evidence for splenic sequestration of in vivo labeled erythrocytes. (7273547)
1981
40
Splenic sequestration of 99mTc labeled, heat treated red blood cells. (7403531)
1980
41
Acute splenic sequestration in hemoglobin sickle O-Arab disease. (7382253)
1980
42
Evidence for splenic sequestration of in vivo-labeled erythrocytes. (7438636)
1980
43
Splenic sequestration syndrome in sickle/hemoglobin C disease at low altitude. (874706)
1977
44
Heterogeneity of rabbit platelets. V. Preferential splenic sequestration of megathrombocytes. (1201241)
1975
45
(51Cr)platelet kinetics in thrombocytopenia. Correlation between splenic sequestration of platelets and response to splenectomy. (4524870)
1974
46
Red cells life span, splenic sequestration and transfusion requirements in chronic renal failure treated by hemodialysis. Effects of bilateral nephrectomy. (4823492)
1974
47
Splenic sequestration of young erythrocytes in sheep. (4686481)
1973
48
Acute splenic sequestration crises (ASSC) in young children with sickle cell anemia. Clinical observations in 20 episodes in 14 children. (4639317)
1972
49
Splenic sequestration of 99m Tc-labeled red blood cells. (5080014)
1972
50
Splenic sequestration of stress erythrocytes in the rabbit. (5414022)
1970

Variations for Splenic Sequestration

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Expression for genes affiliated with Splenic Sequestration

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Splenic Sequestration

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Pathways for genes affiliated with Splenic Sequestration

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Compounds for genes affiliated with Splenic Sequestration

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GO Terms for genes affiliated with Splenic Sequestration

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Products for genes affiliated with Splenic Sequestration

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  • Antibodies
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Sources for Splenic Sequestration

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet