MCID: SPL009
MIFTS: 23

Splenic Sequestration malady

Category: Immune diseases

Aliases & Classifications for Splenic Sequestration

About this section

Aliases & Descriptions for Splenic Sequestration:

Name: Splenic Sequestration 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:11786
ICD9CM29 289.52
UMLS65 C1260402

Summaries for Splenic Sequestration

About this section
MalaCards based summary: Splenic Sequestration is related to breast cancer and heart disease. An important gene associated with Splenic Sequestration is THPO (Thrombopoietin), and among its related pathways is Factors involved in megakaryocyte development and platelet production. Affiliated tissues include spleen, liver and lung.

Related Diseases for Splenic Sequestration

About this section

Graphical network of the top 20 diseases related to Splenic Sequestration:



Diseases related to splenic sequestration

Symptoms for Splenic Sequestration

About this section

Drugs & Therapeutics for Splenic Sequestration

About this section

Drugs for Splenic Sequestration (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Etonogestrelapproved, investigationalPhase 47254048-10-140976, 6917715
Synonyms:
(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
17alpha-ethynyl-17beta-hydroxy-11-methylidene-18a-homo-estr-4-en-3-one
3-Ketodesogestrel
3-Oxodesogestrel
54048-10-1
AC1OCEK1
CHEBI:50777
CHEMBL1531
CID6917715
D04104
 
ETONOGESTREL
Etonogestrel (USAN/INN)
Etonogestrelum
Implanon
Implanon (TN)
MolPort-003-847-336
NCGC00168777-01
Nexplanon
Org-3236
ZINC11680067
etonogestrelum
2
DesogestrelapprovedPhase 44954024-22-540973
Synonyms:
(17alpha)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol
13 Ethyl 11 methylene 18,19 dinor 17 alpha pregn 4 en 20 yn 17 ol
13-Ethyl-11-methylene-18,19-dinor-17 alpha-pregn-4-en-20-yn-17-ol
13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol
17alpha-ethynyl-11-methylidene-18a-homo-estr-4-en-17beta-ol
54024-22-5
AC-308
AC1L24T4
AC1Q282A
C07629
C22H30O
CHEBI:4453
CHEMBL1533
CID40973
Cerazette
D017135
D02367
 
DB00304
DESOGESTREL
Desogestrel (USAN/INN)
Desogestrel [USAN:BAN:INN]
Desogestrelum
Desogestrelum [INN-Latin]
EINECS 258-929-4
HSDB 3593
LMST02030104
LS-62079
MolPort-003-846-424
NCGC00167449-01
ORG 2969
Org-2969
Org2969
Organon Brand of Desogestrel
UNII-81K9V7M3A3
ZINC04097416
alpha-pregn-4-en-20-yn-17-ol, 13-Ethyl-11-methylene-18,19-dinor-17
desogen
3Contraceptive AgentsPhase 41706
4ProgestinsPhase 4433
5
EthylenePhase 42774-85-16325
Synonyms:
Acetene
Athylen
Bicarburretted hydrogen
Elayl
Ethene
Ethene (9CI)
Ethene, 9CI
Ethylene (8CI)
 
Ethylene, compressed [UN1962] [Flammable gas]
Ethylene, pure
Ethylene-CMPD
Etileno
Liquid ethyene
Liquid ethylene
Olefiant gas
Plastipore
Polyethylene as med mol. WT.
6
HydroxyureaapprovedPhase 2188127-07-13657
Synonyms:
1-HYDROXYUREA
127-07-1
4-03-00-00170 (Beilstein Handbook Reference)
55291_FLUKA
AC1L1GF8
AC1Q4ZXK
AI3-51139
BB_SC-7256
BRN 1741548
BSPBio_002164
Bio1_000451
Bio1_000940
Bio1_001429
Biosupressin
C07044
CCRIS 958
CHEBI:44423
CHEMBL467
CID3657
Carbamohydroxamic Acid
Carbamohydroxamic acid
Carbamohydroximic Acid
Carbamohydroximic acid
Carbamohydroxyamic Acid
Carbamohydroxyamic acid
Carbamoyl Oxime
Carbamoyl oxime
Carbamyl Hydroxamate
Carbamyl hydroxamate
Carrbamoyl Oxime
D00341
D006918
DB01005
DRG-0253
DivK1c_000556
Droxia
Droxia (TM)
Droxia (TN)
E0723DBA-5AF3-49D1-B5F6-59420AB87AC9
EINECS 204-821-7
EU-0100596
FT-0083575
H 8627
H0310
H20210
H8627_SIGMA
HMS1920F09
HMS2091L17
HMS501L18
HSDB 6887
HU
HYDREA (TN)
HYDROXY-UREA
Hidrix
Hidroxicarbamida
Hidroxicarbamida [INN-Spanish]
Hydrea
Hydrea (TM)
Hydrea, Biosupressin, Cytodrox, Hydroxyurea
Hydreia
Hydroxicarbamidum
Hydroxycarbamid
Hydroxycarbamide
Hydroxycarbamide (JAN/INN)
Hydroxycarbamidum
Hydroxycarbamidum [INN-Latin]
Hydroxycarbamine
Hydroxyharnstoff
Hydroxyharnstoff [German]
Hydroxylurea
Hydroxyurea
Hydroxyurea (D4)
Hydroxyurea (USP)
Hydroxyurea [USAN:BAN]
Hydroxyurea(d4)
 
Hydura
Hydurea
I05-0250
IDI1_000556
Idrossicarbamide
Idrossicarbamide [DCIT]
Idrossicarbamide [Dcit]
KBio1_000556
KBio2_001389
KBio2_003957
KBio2_006525
KBio3_001384
KBioGR_000383
KBioSS_001389
LS-709
Litaler
Litalir
Lopac-H-8627
Lopac0_000596
MLS001332381
MLS001332382
MLS002153389
MolMap_000029
MolPort-000-003-971
Mylocel
N-(Aminocarbonyl) Hydroxyamine
N-Carbamoylhydroxylamine
N-HYDROXY UREA
N-Hydroxymocovina
N-Hydroxymocovina [Czech]
N-Hydroxyurea
NCGC00015520-01
NCGC00015520-02
NCGC00015520-07
NCGC00093974-01
NCGC00093974-02
NCGC00093974-03
NCGC00093974-04
NCGC00093974-05
NCI C04831
NCI-C04831
NCI60_002773
NCIMech_000139
NHY
NINDS_000556
NSC 32065
NSC32065
Onco-Carbide
Onco-carbide
Oncocarbide
Oxyurea
S-phase/G-1 interface inhibitor
S1896_Selleck
SK 22591
SMR000059149
SPBio_000247
SPECTRUM1500344
SQ 1089
SQ-1089
Siklos
Spectrum2_000064
Spectrum3_000462
Spectrum4_000012
Spectrum5_000836
Spectrum_000909
Sterile Urea
TL8000673
UNII-X6Q56QN5QC
Ureaphil
WLN: ZVMQ
carbamide oxide
hydroxyaminomethanamide
hydroxyurea
nchembio.573-comp3
nchembio.90-comp4
nchembio749-comp3
tetratogen: inhibits ribonucleoside diphosphate reductase
7Nucleic Acid Synthesis InhibitorsPhase 23836
8ImmunoglobulinsPhase 24477
9Antibodies, MonoclonalPhase 22413
10AntibodiesPhase 24477

Interventional clinical trials:

idNameStatusNCT IDPhase
1Contraception in Women With Sickle Cell DiseaseActive, not recruitingNCT02594462Phase 4
2Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain CrisesCompletedNCT01895361Phase 2
3The Spleen in Sickle Cell Anemia and Sickle Cell ThalassemiaCompletedNCT00971698
4Prognostic Factors of Acute Splenic SequestrationActive, not recruitingNCT01207037

Search NIH Clinical Center for Splenic Sequestration

Genetic Tests for Splenic Sequestration

About this section

Anatomical Context for Splenic Sequestration

About this section

MalaCards organs/tissues related to Splenic Sequestration:

33
Spleen, Liver, Lung, Heart, Bone, T cells, Cervix

Animal Models for Splenic Sequestration or affiliated genes

About this section

Publications for Splenic Sequestration

About this section

Articles related to Splenic Sequestration:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Multimodality imaging in heart valve disease. (26977308)
2016
2
Tubulocystic carcinoma of the kidney. (26130898)
2015
3
Mutational analysis of oncogenic CSF3R p.T618I in acute leukemias and common solid cancers. (25404019)
2015
4
High-resolution computed tomography findings of acute respiratory distress syndrome, acute interstitial pneumonia, and acute exacerbation of idiopathic pulmonary fibrosis. (24480142)
2014
5
Toxocariasis and lung function: relevance of a neglected infection in an urban landscape. (24570059)
2014
6
The beneficial effect of plasmapheresis in mixed connective tissue disease with coexisting antiphospholipid syndrome. (24795068)
2014
7
Efficacy of pirfenidone in patients with advanced-stage idiopathic pulmonary fibrosis. (24240787)
2013
8
Effects of Long-Term Hypoxia and Pro-Survival Cocktail in Bone Marrow-Derived Stromal Cell Survival. (24147599)
2013
9
Tracheal agenesis: approach towards this severe diagnosis. Case report and review of the literature. (21918809)
2012
10
Secretion of ATP from Schwann cells through lysosomal exocytosis during Wallerian degeneration. (23142593)
2012
11
Effectiveness and satisfaction with imiquimod for the treatment of superficial basal cell carcinoma in daily dermatological practice. (21348896)
2011
12
The case for newborn screening for severe combined immunodeficiency and related disorders. (22236435)
2011
13
Serotonin syndrome in a postoperative cardiac surgical patient--a case report. (21991742)
2011
14
Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis. (20094053)
2010
15
Late acute celiac and hepatic artery thrombosis with portal vein thrombosis resulting in hepatic infarction 12 years post orthotopic liver transplantation. (20009144)
2009
16
Inhibition of fipronil and nonane metabolism in human liver microsomes and human cytochrome P450 isoforms by chlorpyrifos. (17427179)
2007
17
The role of CETP inhibition in dyslipidemia. (17877921)
2007
18
Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. (17064680)
2007
19
Tumor cell lines expressing the proteasome subunit isoform LMP7E1 exhibit immunoproteasome deficiency. (16423992)
2006
20
The mutation rate in PIG-A is normal in patients with paroxysmal nocturnal hemoglobinuria (PNH). (16543465)
2006
21
Serum levels of matrix metalloproteinase-9 and its tissue inhibitor (TIMP-1) in acute disseminated encephalomyelitis. (16321449)
2006
22
HIV-1 Tat protein concomitantly down-regulates apical caspase-10 and up-regulates c-FLIP in lymphoid T cells: a potential molecular mechanism to escape TRAIL cytotoxicity. (15573381)
2005
23
Chronic inflammation of the peritoneum and vagina: review of its significance, immunologic pathogenesis, investigation and rationale for treatment. (16130848)
2005
24
Plasma prekallikrein as a risk factor for diabetic retinopathy. (16099335)
2005
25
Signet-ring cell ependymoma with intratumoral hemorrhage in the medulla oblongata. (16115557)
2005
26
Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions. (14967033)
2004
27
Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix. (15623619)
2004
28
The management of slipped capital femoral epiphysis. (15274254)
2004
29
Doxycycline in the treatment of human onchocerciasis: Kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms. (12706439)
2003
30
Influence of calcium-sensing receptor gene on urinary calcium excretion in stone-forming patients. (12239240)
2002
31
The aetiology of gingival recession. (11928341)
2002
32
Towards the structure of the mammalian signal recognition particle. (11839493)
2002
33
Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. (11316217)
2001
34
Differential phosphorylation of tau proteins during kitten brain development and Alzheimer's disease. (11577253)
2001
35
Clotrimazole inhibits lung fibroblast proliferation in vitro: implications for use in the prevention and treatment of obliterative bronchiolitis after lung transplantation. (11063355)
2000
36
Polymorphisms of TAP1 and TAP2 genes in Graves' disease. (9027960)
1997
37
Lipoprotein glomerulopathy: a pediatric case report. (9090668)
1997
38
Nerve root hypertrophy as the cause of lumbar stenosis in chronic inflammatory demyelinating polyradiculoneuropathy. (8965844)
1996
39
Molecular characterization of the spliceosomal proteins U1A and U2B" from higher plants. (7556097)
1995
40
Cholelithiasis with common bile duct obstruction in a 20-week-old infant. (7756241)
1995
41
Significance of soluble interleukin-2 receptor levels for evaluation of the progression of adult T-cell leukemia. (8194016)
1994
42
Diagnosis of alpha-mannosidosis by measuring alpha-mannosidase in plasma. (1568314)
1992
43
Gastric protection by nocloprost against aspirin damage in humans. Possible role of epidermal growth factor. (1853145)
1991
44
DXS165 detects a translocation breakpoint in a woman with choroideremia and a de novo X; 13 translocation. (2341150)
1990
45
Thromboxane synthase inhibition and thromboxane/endoperoxide receptor antagonism in a chronic canine model of coronary thrombosis. (2959103)
1987
46
Six cases of malignant atrophic papulosis (Degos' disease) occurring in one family. (6487548)
1984
47
Serologic classification of scrub typhus isolates from Pakistan. (46135)
1975
48
Carotidynia. A distinct syndrome. (6016255)
1967
49
What can be done to prevent coronary thrombosis? (5179794)
1966
50
EFFECT OF DIETARY SELENIUM ON INCIDENCE OF NUTRITIONAL ENCEPHALOMALACIA IN CHICKS. (14229102)
1964

Variations for Splenic Sequestration

About this section

Expression for genes affiliated with Splenic Sequestration

About this section
Search GEO for disease gene expression data for Splenic Sequestration.

Pathways for genes affiliated with Splenic Sequestration

About this section

Pathways related to Splenic Sequestration according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2HBB, HBD

GO Terms for genes affiliated with Splenic Sequestration

About this section

Sources for Splenic Sequestration

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet