MCID: SPN225
MIFTS: 63

Spondyloarthropathy 1 malady

Categories: Genetic diseases, Rare diseases, Bone diseases

Aliases & Classifications for Spondyloarthropathy 1

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Aliases & Descriptions for Spondyloarthropathy 1:

Name: Spondyloarthropathy 1 51 69 34
Ankylosing Spondylitis 34 11 47 25 69 37 13 67
Spondylitis, Ankylosing 25 26 38
Bechterew Syndrome 47 24 69
Spondylarthritis Ankylopoietica 25 69
Marie-Strumpell Spondylitis 47 69
Reiter Syndrome 69 67
Ankylosing Spondylitis, Susceptibility to 24
Spondyloarthropathy, Susceptibility to, 1 12
Spondyloarthropathy 1, Susceptibility to 24
Ankylosing Spondylitis Risk Factor 24
Spondyloarthritis Ankylopoietica 25
Ankylosing Spondyloarthritis 47
Ankylosing Spondylarthritis 69
Spondylitis Ankylopoietica 25
Marie-Strumpel Spondylitis 24
 
Marie-Struempell Disease 25
Marie-Strumpell Disease 11
Spondylitis Ankylosing 49
Spondylitis Ankylosans 69
Rheumatoid Spondylitis 69
Spondylarthropathies 67
Arthritis, Psoriatic 67
Psoriatic Arthritis 69
Bekhterev's Disease 11
Arthritis, Reactive 67
Reactive Arthritis 69
Bekhterev Syndrome 11
Bechterew Disease 25
Spda1 69
As 25

Characteristics:

HPO:

63
spondyloarthropathy 1:
Inheritance: multifactorial inheritance

Classifications:



External Ids:

OMIM51 106300
Disease Ontology11 DOID:7147
ICD1029 M45
ICD9CM31 720.0
SNOMED-CT61 156619005, 9631008
NCIt44 C84564

Summaries for Spondyloarthropathy 1

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OMIM:51 Spondyloarthropathy (SpA), one of the commonest chronic rheumatic diseases, includes a spectrum of related disorders... (106300) more...

MalaCards based summary: Spondyloarthropathy 1, also known as ankylosing spondylitis, is related to psoriasis and heart disease, and has symptoms including abnormality of the oral cavity, arthritis and joint swelling. An important gene associated with Spondyloarthropathy 1 is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Cellular Transformation by HTLV1 and Transcription_NF-kB signaling pathway. The drugs etanercept and auranofin have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and testes, and related mouse phenotypes are craniofacial and homeostasis/metabolism.

UniProtKB/Swiss-Prot:69 Spondyloarthropathy 1: A chronic rheumatic disease with multifactorial inheritance. It includes a spectrum of related disorders comprising ankylosing spondylitis, a subset of psoriatic arthritis, reactive arthritis (e.g. Reiter syndrome), arthritis associated with inflammatory bowel disease and undifferentiated spondyloarthropathy. These disorders may occur simultaneously or sequentially in the same patient, probably representing various phenotypic expressions of the same disease. Ankylosing spondylitis is the form of rheumatoid arthritis affecting the spine and is considered the prototype of seronegative spondyloarthropathies. It produces pain and stiffness as a result of inflammation of the sacroiliac, intervertebral, and costovertebral joints.

MedlinePlus:37 Ankylosing spondylitis is a type of arthritis of the spine. it causes inflammation between your vertebrae, which are the bones that make up your spine, and in the joints between your spine and pelvis. in some people, it can affect other joints. as is more common and more severe in men. it often runs in families. the cause is unknown, but it is likely that both genes and factors in the environment play a role. early symptoms of as include back pain and stiffness. these problems often start in late adolescence or early adulthood. over time, as can fuse your vertebrae together, limiting movement. some people have symptoms that come and go. others have severe, ongoing pain. a diagnosis of as is based on your medical history and a physical examination. you may also have imaging or blood tests. as has no cure, but medicines can relieve symptoms and may keep the disease from getting worse. eating a healthy diet, not smoking, and exercising can also help. in rare cases, you may need surgery to straighten the spine. nih: national institute of arthritis and musculoskeletal and skin disease

Genetics Home Reference:25 Ankylosing spondylitis is a form of ongoing joint inflammation (chronic inflammatory arthritis) that primarily affects the spine. This condition is characterized by back pain and stiffness that typically appear in adolescence or early adulthood. Over time, back movement gradually becomes limited as the bones of the spine (vertebrae) fuse together. This progressive bony fusion is called ankylosis.

Disease Ontology:11 A bone inflammation disease that results in inflammation in the joints of the spine and pelvis. The disease has symptom pain, has symptom stiffness in the spine, has symptom stiffness in the neck, has symptom stiffness in the hips, has symptom stiffness in the jaw and has symptom stiffness in the rib cage.

NIH Rare Diseases:47 Ankylosing spondylitis (AS) is a type of chronic, inflammatory arthritis that mainly affects the spine. It usually begins with inflammation of the joints between the pelvic bones and spine, gradually spreading to the joints between the vertebrae. Signs and symptoms usually begin in adolescence or early adulthood and may include back pain and stiffness. Back movement gradually becomes more limited as the vertebrae fuse together. The condition may also affect the shoulders; ribs; hips; knees; and feet; as well as the eyes; bowel; and very rarely, the heart and lungs. AS is likely caused by a combination of genetic and environmental factors; variations in several genes are thought to affect the risk to develop AS. In most cases, treatment involves exercise and medications to relieve pain and inflammation. Last updated: 2/9/2015

Related Diseases for Spondyloarthropathy 1

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Diseases in the Spondyloarthropathy family:

Spondyloarthropathy 3 spondyloarthropathy 1
Spondyloarthropathy 2 Juvenile Spondyloarthropathy

Diseases related to Spondyloarthropathy 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 389)
idRelated DiseaseScoreTop Affiliating Genes
1psoriasis30.9CD40LG, CD79A, TNFRSF1B
2heart disease30.7CD40LG, CD79A
3artery disease30.6CD40LG, CD79A, CRP
4retroperitoneal fibrosis30.0CD40LG, IL1RN, TNF
5systemic lupus erythematosus30.0CD40LG, CD79A, CRP, TNF, TNFRSF1B
6myelitis29.6CD40LG, IL17A, TNF, TNFRSF1A
7atherosclerosis28.2ANKH, IL17A, IL1RN, MMP3, TNF, TNFRSF1B
8rheumatoid arthritis26.7CD40LG, CD79A, CRP, HLA-B, IL17A, IL1RN
9smoking as a quantitative trait locus 111.8
10smoking as a quantitative trait locus 211.8
11angelman syndrome11.5
12osteochondrosis11.3
13spondylitis11.3
14ossification of the posterior longitudinal ligament of the spine11.1
15common variable immunodeficiency10.7HLA-B, TNF
16panner disease10.7CRP, TNF
17arthritis10.7
18uveoparotid fever10.7TNF, TNFRSF1B
19brain stem cancer10.7TNF, TNFRSF1B
20calcific tendinitis10.7CD40LG, CD79A
21medullary sponge kidney10.7CD40LG, CD79A
22variola major10.6CD40LG, CD79A
23mu chain disease10.6CD40LG, CD79A
24retinal cancer10.6CD40LG, CD79A
25focal embolic glomerulonephritis10.6CD40LG, CD79A
26endometrial stromal nodule10.6CD40LG, CD79A
27vaginal mullerian papilloma10.6CD79A, CRP
28chronic cystitis10.6CD40LG, CD79A
29epstein-barr virus hepatitis10.6CRP, HLA-B, TNF
30van benthem-driessen-hanveld syndrome10.6CD40LG, CD79A
31hemolytic-uremic syndrome10.6CD40LG, CD79A
32partial motor epilepsy10.6CD40LG, CD79A
33benign meningioma10.6CD40LG, CD79A
34parasitic helminthiasis infectious disease10.6CD40LG, CD79A
35occlusion of gallbladder10.6CD40LG, CD79A
36gonococcal iridocyclitis10.6HLA-B, MRAP
37basal ganglia cerebrovascular disease10.6CRP, MRAP
38acneiform dermatitis10.6NOD2, TNF
39viral meningitis10.6CD40LG, CD79A
40substance-induced psychosis10.6CD40LG, CD79A
41pulmonary systemic sclerosis10.6CRP, HLA-B, TNF
42bone cancer10.6CD40LG, CRP
43gamma heavy chain disease10.6CD40LG, CD79A
44extrahepatic cholestasis10.5CD79A, CRP, TNF
45dehydration polycythemia10.5CD40LG, CRP
46regional ureteric cancer10.5CD40LG, CD79A
47arteriosclerosis10.5CD40LG, CD79A
48pompholyx10.5CD40LG, CD79A
49exocrine pancreatic insufficiency10.5CD79A, CRP, TNF
50brucella abortus brucellosis10.5CD40LG, CD79A, TNF

Comorbidity relations with Spondyloarthropathy 1 via Phenotypic Disease Network (PDN):


Rheumatoid ArthritisHypertension, Essential
OsteoporosisDeficiency Anemia
Acute Cystitis

Graphical network of the top 20 diseases related to Spondyloarthropathy 1:



Diseases related to spondyloarthropathy 1

Symptoms for Spondyloarthropathy 1

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Symptoms by clinical synopsis from OMIM:

106300

Clinical features from OMIM:

106300

Symptoms:

 11 (show all 6)
  • pain
  • stiffness in the spine
  • stiffness in the neck
  • stiffness in the hips
  • stiffness in the jaw
  • stiffness in the rib cage

Human phenotypes related to Spondyloarthropathy 1:

 63 (show all 45)
id Description HPO Frequency HPO Source Accession
1 abnormality of the oral cavity63 hallmark (90%) HP:0000163
2 arthritis63 hallmark (90%) HP:0001369
3 joint swelling63 hallmark (90%) HP:0001386
4 diarrhea63 hallmark (90%) HP:0002014
5 arthralgia63 hallmark (90%) HP:0002829
6 spinal rigidity63 hallmark (90%) HP:0003306
7 abnormal form of the vertebral bodies63 hallmark (90%) HP:0003312
8 inflammatory abnormality of the eye63 hallmark (90%) HP:0100533
9 enthesitis63 hallmark (90%) HP:0100686
10 abnormality of the sacroiliac joint63 hallmark (90%) HP:0100781
11 abnormality of the thorax63 typical (50%) HP:0000765
12 respiratory insufficiency63 typical (50%) HP:0002093
13 myalgia63 typical (50%) HP:0003326
14 recurrent urinary tract infections63 occasional (7.5%) HP:0000010
15 renal insufficiency63 occasional (7.5%) HP:0000083
16 proteinuria63 occasional (7.5%) HP:0000093
17 nephrotic syndrome63 occasional (7.5%) HP:0000100
18 nephropathy63 occasional (7.5%) HP:0000112
19 nephrolithiasis63 occasional (7.5%) HP:0000787
20 hematuria63 occasional (7.5%) HP:0000790
21 hyperkeratosis63 occasional (7.5%) HP:0000962
22 skin rash63 occasional (7.5%) HP:0000988
23 abnormality of the aortic valve63 occasional (7.5%) HP:0001646
24 abnormality of the pericardium63 occasional (7.5%) HP:0001697
25 abdominal pain63 occasional (7.5%) HP:0002027
26 anorexia63 occasional (7.5%) HP:0002039
27 abnormality of the pleura63 occasional (7.5%) HP:0002103
28 pulmonary fibrosis63 occasional (7.5%) HP:0002206
29 osteomyelitis63 occasional (7.5%) HP:0002754
30 recurrent fractures63 occasional (7.5%) HP:0002757
31 autoimmunity63 occasional (7.5%) HP:0002960
32 abnormality of temperature regulation63 occasional (7.5%) HP:0004370
33 hemiplegia/hemiparesis63 occasional (7.5%) HP:0004374
34 arrhythmia63 occasional (7.5%) HP:0011675
35 abnormal tendon morphology63 occasional (7.5%) HP:0100261
36 cartilage destruction63 occasional (7.5%) HP:0100773
37 pustule63 occasional (7.5%) HP:0200039
38 skin ulcer63 occasional (7.5%) HP:0200042
39 aortic regurgitation63 HP:0001659
40 inflammation of the large intestine63 HP:0002037
41 kyphosis63 HP:0002808
42 back pain63 HP:0003418
43 psoriasis63 HP:0003765
44 hip osteoarthritis63 HP:0008843
45 anterior uveitis63 HP:0012122

UMLS symptoms related to Spondyloarthropathy 1:


pathergy reaction, joint related signs and symptoms, sciatica, muscle cramp, exanthema, back pain

Drugs & Therapeutics for Spondyloarthropathy 1

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Drugs for Spondyloarthropathy 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 225)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
SulfasalazineapprovedPhase 4, Phase 2, Phase 3, Phase 161599-79-15353980, 5359476
Synonyms:
13gs
2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID
2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid
2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid
2-hydroxy-5-(4-[(pyridin-2-ylamino)sulfonyl]phenyl}diazenyl)benzoic acid
2-hydroxy-5-[(E)-{4-[(pyridin-2-ylamino)sulfonyl]phenyl}diazenyl]benzoic acid
2-hydroxy-5-{[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid
4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene
5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid
5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid
5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid
5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid
5-(p-(2-Pyridinylsulfamoyl)Phenylazo)Salicylic Acid
5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid
5-(para-(2-pyridylsulfamoyl)phenylazo)salicylic acid
5-22-08-00433 (Beilstein Handbook Reference)
5-[4-(2-Pyridylsulfamoyl)-phenylazo]-salicylic acid
5-[4-(2-Pyridylsulfamoyl)phenylazo]salicylic Acid
5-[p-(2-Pyridylsulfamoyl)phenylazo]salicylic acid
5-[p-(2-Pyridylsulfamyl)phenylazo]salicylic acid
599-79-1
AC-20497
AC1NS4RK
AC1NSE0P
AC1NTMDP
AC1Q72VB
AKOS002311709
Accucol
Alphapharm Brand of Sulfasalazine
Alti-Sulfasalazine
Ashbourne Brand of Sulfasalazine
Asulfidine
Azlufidine EN-Tabs
Azopyrin
Azopyrine
Azosulfidin
Azulfadine
Azulfidine
Azulfidine (TN)
Azulfidine EN
Azulfidine EN-Tabs
Azulfidine EN-tabs
BIDD:GT0161
BPBio1_000527
BRD-K10670311-001-06-4
BRN 0356241
BSPBio_000479
BSPBio_002888
Benzosulfa
C07316
C18H14N4O5S
CAS-599-79-1
CCRIS 4713
CHEBI:45504
CHEBI:489907
CHEBI:9334
CHEMBL242373
CHEMBL421
CID5353980
CID5359476
CID5384001
CPD000059146
Colo Pleon
Colo-Pleon
D00448
D012460
DB00795
DB08518
DivK1c_000860
EINECS 209-974-3
EN, Azulfidine
FNA Brand of Sulfasalazine
HMS1569H21
HMS1921C05
HMS2051J21
HMS2090P13
HMS2092K07
HMS502K22
HSDB 3395
Henning Berlin Brand of Sulfasalazine
Heyl Brand of Sulfasalazine
I06-0676
IDI1_000860
KBio1_000860
KBio2_001478
KBio2_002314
KBio2_004046
KBio2_004882
KBio2_006614
KBio2_007450
KBio3_002108
KBio3_002794
KBioGR_000753
KBioGR_002314
KBioSS_001478
 
KBioSS_002316
LS-46
MLS000759399
MLS001424109
MolPort-001-792-507
MolPort-003-986-992
NCGC00016518-01
NCGC00090903-01
NCGC00090903-02
NCGC00090903-03
NCGC00090903-04
NCGC00090903-05
NINDS_000860
NSC 203730
NSC 667219
NSC203730
NSC667219
PMS-Sulfasalazine
Pfizer Brand of Sulfasalazine
Pleon
Pms-Sulfasalazine E.C.
Prestwick0_000520
Prestwick1_000520
Prestwick2_000520
Prestwick3_000520
Prestwick_848
Pyralin EN
Ratiopharm Brand of Sulfasalazine
Reupirin
Rorasul
S.A.S. 500
S.A.S. Enteric-500
S.A.S.-500
S0580
SAM001246530
SASP
SBB058178
SI-88
SMP2_000059
SMR000059146
SPBio_001032
SPBio_002400
SPECTRUM1500552
SSZ
ST50767935
Salazo-sulfapyridinum
Salazopiridazin
Salazopyridin
Salazopyrin
Salazopyrin en-tabs
Salazopyrin EN-Tabs
Salazosulfapiridina
Salazosulfapiridina [INN-Spanish]
Salazosulfapyridin
Salazosulfapyridine
Salazosulfapyridine (JP15)
Salazosulfapyridinum
Salazosulfapyridinum [INN-Latin]
Salicylazosulfapyridine
Salisulf
Sanofi Synthelabo Brand of Sulfasalazine
Sas-500
Spectrum2_001216
Spectrum3_001364
Spectrum4_000347
Spectrum5_001443
Spectrum_000998
Sulcolon
Sulfasalazin
Sulfasalazin Heyl
Sulfasalazin medac
Sulfasalazin-Heyl
Sulfasalazina
Sulfasalazina [INN-Spanish]
Sulfasalazine
Sulfasalazine (USP/INN)
Sulfasalazine FNA
Sulfasalazine Pfizer Brand
Sulfasalazine [USAN:INN]
Sulfasalazinum
Sulfasalazinum [INN-Latin]
Sulfazalazine
Sulphasalazine
TL8003811
UNII-3XC8GUZ6CB
Ucine
Ulcol
W-T Sasp Oral
WLN: T6NJ BSWMR DNUNR DQ CVQ
cMAP_000018
medac Brand of Sulfasalazine
nchembio.212-comp9
ratio Sulfasalazine
ratio-Sulfasalazine
sulfasalazine
w-t Sasp oral
2
Certolizumab pegolapprovedPhase 4, Phase 3, Phase 1122428863-50-7
Synonyms:
428863-50-7
CDP870
Certolizumab pegol
 
Certolizumab pegol (USAN/INN)
Certolizumab pegol (genetical recombination)
Certolizumab pegol (genetical recombination) (JAN)
D03441
cimzia
3
AdalimumabapprovedPhase 4, Phase 2, Phase 3478331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
4
MethotrexateapprovedPhase 4, Phase 2, Phase 3, Phase 115181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
5
Etanerceptapproved, investigationalPhase 4, Phase 3, Phase 2397185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
6
InfliximabapprovedPhase 4, Phase 3, Phase 2, Phase 1378170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
7
Celecoxibapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 1435169590-42-52662
Synonyms:
169590-42-5
184007-95-2
1oq5
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazol-1-yl] benzenesulfonamide
4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
AC-4228
AC1L1E6K
AI-525
BIDD:GT0408
BRD-K02637541-001-02-4
BSPBio_003596
Benzenesulfonamide,4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)
C07589
C105934
C17H14F3N3O2S
CCRIS 8679
CEL
CEP-33222
CHEBI:41423
CHEMBL118
CID2662
CPD000550473
Celebra
Celebrex
Celebrex (TN)
Celebrex, Celebra, Celecoxib
Celecox
Celecoxi
Celecoxib
Celecoxib (JAN/USAN/INN)
Celecoxib (SC-58635)
Celecoxib [Old RN]
Celecoxib [USAN]
Celecoxibum
Celocoxib
Célécoxib
D00567
DB00482
DivK1c_000893
Eurocox
FT-0080064
HMS1922G14
HMS2089L18
HMS2093I07
HMS502M15
HSDB 7038
I01-1033
IDI1_000893
KBio1_000893
KBio2_000912
 
KBio2_002351
KBio2_003480
KBio2_004919
KBio2_006048
KBio2_007487
KBio3_002830
KBio3_003037
KBioGR_000723
KBioGR_002351
KBioSS_000912
KBioSS_002354
LS-31667
MLS001165684
MLS001195656
MLS001304708
Medicoxib
MolPort-002-885-815
NCGC00091455-01
NCGC00091455-02
NCGC00091455-03
NCGC00091455-04
NCI60_041049
NINDS_000893
NSC719627
Onsenal
P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
Pfizer brand of celecoxib
S1261_Selleck
SAM002589995
SC 58635
SC-58553, SC-58635
SC-58635
SC58635
SMR000550473
SPBio_001512
SPECTRUM1503678
Solexa
Spectrum2_001576
Spectrum3_001996
Spectrum4_000182
Spectrum5_001324
Spectrum_000432
TL8001323
TPI-336
UNM-0000305813
Xilebao
YM 177
YM-177
YM177
ZINC02570895
cMAP_000027
celecoxib
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
8
Etoricoxibapproved, investigationalPhase 4, Phase 3, Phase 292202409-33-4123619
Synonyms:
202409-33-4
5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
5-Chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
5CH
AC1L3WZM
Algix
Arcoxia
C11718
C422649
CHEBI:106706
CHEBI:6339
CHEMBL416146
CID123619
D03710
DB01628
DB07166
ETORICOXIB
 
Etoricoxib
Etoricoxib (USAN/INN)
Etoricoxib [USAN:INN:BAN]
Etoricoxibe
Etoricoxibum
FT-0082494
HMS2090A05
L-791456
L001141
L791456
LS-181802
MK 0663
MK 663
MK-0663
MK-663
Merck Sharp & Dohme brand of etoricoxib
MolPort-003-847-339
NCGC00164578-01
Nucoxia
Tauxib
UNII-WRX4NFY03R
ZINC00579472
9
Apremilastapproved, investigationalPhase 4, Phase 3, Phase 264608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
Apremilastum
Aprémilast
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
10
PamidronateapprovedPhase 4, Phase 1, Phase 24440391-99-94674
Synonyms:
(3-AMINO-1-HYDROXY-1-PHOSPHONO-PROPYL)PHOSPHONIC ACID
(3-Amino-1-hydroxypropylidene)bisphosphonic acid
(3-Amino-1-hydroxypropylidene)diphosphonic acid
(3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
(3-amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)
(3-amino-1-hydroxypropylidene)-1,1-biphosphonate
(3-amino-1-hydroxypropylidene)-1,1-bisphosphonate
1-hydroxy-3-aminopropane-1,1-diphosphonic acid
3-Amino-1-hydroxypropylidene-1,1-diphosphonate
40391-99-9
57248-88-1
57248-88-1 (di-hydrochloride salt)
AC1L1IP4
AHPrBP
AKOS003599275
APD
Acide pamidronique
Acide pamidronique [INN-French]
Acido pamidronico
Acido pamidronico [INN-Spanish]
Acidum pamidronicum
Acidum pamidronicum [INN-Latin]
Amidronate
Aminomux
Aredia
BIDD:GT0538
Bisphosphonate 6
C019248
C07395
C3H11NO7P2
 
CHEMBL834
CID4674
ChemDiv1_025240
D07281
DB00282
EINECS 254-905-2
HMS2090C13
HMS658L06
HSCI1_000312
I14-2407
LS-174826
MolPort-002-131-054
NCGC00159433-02
NCGC00159433-03
Novartis brand of pamidronate disodium salt
PAMIDRONATE DISODIUM
PAMIDRONIC ACID
Pamidronate Disodium
Pamidronic acid
Pamidronic acid (INN)
Pamidronic acid [INN:BAN]
Ribodroat
Ribodroat (TN)
STOCK1N-12562
UNII-OYY3447OMC
amino-1-hydroxypropane-1,1-diphosphonate
aminohydroxypropylidene diphosphonate
aminopropanehydroxydiphosphonate
pamidronate
pamidronate calcium
pamidronate monosodium
11
MentholapprovedPhase 4, Phase 323532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
12
Tramadolapproved, investigationalPhase 423227203-92-533741
Synonyms:
(+)-(R,R)-trans-Tramadol
(+)-Tramadol
(+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol
(+)-trans-Tramadol free ba
(1R,2R)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexan-1-ol
(1R,2R)-2-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexanol
(1R,2R)-2-[(dimethylamino)methyl]-1-[3-(methyloxy)phenyl]cyclohexanol
27203-92-5
AC1L1Q6E
AC1Q59O2
AKOS005066335
Amanda
Amanda (TN)
BIDD:GT0075
C07153
CHEMBL1066
CID33741
Crispin
D08623
DB00193
EINECS 248-319-6
HMS2090D10
Jsp005295
LS-57115
 
LS-57116
MLS000333190
MolPort-002-507-778
NCGC00159343-02
Ralivia ER
Ralivia Flashtab
Ralivia flashtab
SMR000436547
STOCK4S-19075
Tradonal odis
Tramadol
Tramadol (INN)
Tramadol HCl
Tramadol HCl BP/EP
Tramadol [INN:BAN]
Tramadol hydrochloride
Tramadolum
Tramadolum [INN-Latin]
Tramal
Tramodol Hcl
Tridural
UNII-39J1LGJ30J
Ultram
Ultram ER
Zydol
tramadol
13
AcetaminophenapprovedPhase 4978103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
14
Diclofenacapproved, vet_approvedPhase 4, Phase 330915307-86-53033
Synonyms:
(2,6-Dichlorophenyl)amino]benzeneacetic acid
15307-81-0 (mono-potassium salt)
15307-86-5
2-((2,6-Dichlorophenyl)amino)benzeneacetic acid
2-((2,6-dichlorophenyl)amino)benzeneacetic acid
2-(2,6-Dichloroanilino)phenylacetic Acid
2-(2,6-Dichlorophenylamino)phenylacetic acid
2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid
2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID
2-[2-(2,6-Dichlorophenylamino)phenyl]acetic acid
2-[2-(2,6-dichloroanilino)phenyl]acetic acid
2b17
AC1L1F0T
AKOS001579542
Acetic acid, [o-(2,6-dichloroanilino)phenyl]- (8CI)
Allvoran
Apo-Diclo
Assaren
BIDD:GT0380
BPBio1_000516
BRD-K08252256-236-05-6
BRN 2146636
BSPBio_000468
BSPBio_002169
Benfofen
Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)- (9CI)
C01690
CHEBI:47381
CHEMBL139
CID3033
Cataflam
D07816
D30801
D3748
DB00586
DIF
Delphimix
Dichlofenac
Dichlofenal
Dichronic
Diclac
Diclo-Phlogont
Diclo-Puren
Diclobenin
Diclofenac (INN)
Diclofenac Acid
Diclofenac Potassium
Diclofenac Sodium
Diclofenac [INN:BAN]
Diclofenac acid
Diclofenaco
Diclofenaco [INN-Spanish]
Diclofenacum
Diclofenacum [INN-Latin]
Diclofenamic acid
Diclomelan
Diclonate P
Diclophenac
Diclord
Dicloreum
Dicloreuma
Dicrofenac
DivK1c_000272
DivK1c_000402
Dolobasan
Duravolten
Dyloject
EINECS 239-348-5
Ecofenac
Effekton
GP-45,840
HMS2090C10
HMS501E04
HSDB 7234
I14-7739
 
IDI1_000272
IDI1_000402
ISV-205
KBio1_000272
KBio1_000402
KBio2_001410
KBio2_002306
KBio2_003978
KBio2_004874
KBio2_006546
KBio2_007442
KBio3_001389
KBio3_002786
KBioGR_001051
KBioGR_002306
KBioSS_001410
KBioSS_002308
Kriplex
LS-11575
Lopac0_000441
MolPort-000-003-072
N-(2,6-Dichlorop
NCGC00021125-01
NINDS_000272
NINDS_000402
Neriodin
Novapirina
Novo-Difenac
Novo-Difenac SR
Nu-Diclo
Oprea1_011155
Orthofen
Pennsaid
Prestwick0_000594
Prestwick1_000594
Prestwick2_000594
Prestwick3_000594
Primofenac
ProSorb-D
Prophenatin
Rhumalgan
SBB068617
SPBio_001081
SPBio_002687
SR-38
STK984493
Solaraze
Solaraze (TN)
Solaraze T
Spectrum2_000991
Spectrum3_000385
Spectrum4_000506
Spectrum5_000867
Spectrum_000930
Transfenac
Tsudohmin
UNII-144O8QL0L1
UNM000001216103
Valetan
Voldal
Voltaflan
Voltaren
Voltaren Ophtha
Voltaren Ophthalmic
Voltaren Rapide
Voltaren SR
Voltaren ophthalmic
Voltaren-XR
Voltarol
Xenid
[2-(2,6-dichloroanilino)phenyl]acetic acid
[o-(2,6-Dichloroanilino)phenyl]acetic acid
cMAP_000014
dichlofenac
diclofenac
henyl)-o-aminophenylacetic acid
{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid
15
Naproxenapproved, vet_approvedPhase 4, Phase 325122204-53-11302, 156391
Synonyms:
(+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
(+)-(S)-Naproxen
(+)-2-(6-Methoxy-2-naphthyl)propionic acid
(+)-2-(Methoxy-2-naphthyl)-propionic acid
(+)-2-(Methoxy-2-naphthyl)-propionsaeure
(+)-2-(Methoxy-2-naphthyl)-propionsaeure [German]
(+)-2-(Methoxy-2-naphthyl)-propionsäure
(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(+)-Naproxen
(+)NAPROXEN
(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
(S)-()-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-()-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-(+)-Naproxen
(S)-2-(6-Methoxy-2-naphthyl)propanoic acid
(S)-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-6-Methoxy-.alpha.-methyl-2-naphthaleneacetic acid
(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-Naproxen
2-(6-Methoxy-2-naphthyl)propionic acid
2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (+)- (8CI)
22204-53-1
284785_ALDRICH
46482_FLUKA
46482_RIEDEL
65126_FLUKA
AC-1363
AC1L4G3X
AC1Q4ET9
AC1Q4F4H
AC1Q4F4I
ARONIS24306
Acusprain
Aleve
Anaprox
Anax
Anexopen
Apo-Napro-NA
Apo-Naproxen
Apronax
Artagen
Arthrisil
Artrixen
Artroxen
Atiflan
Axer
BIDD:GT0062
BRD-K59197931-001-02-9
BRD-K59197931-236-09-6
BSPBio_002067
Bipronyl
Bonyl
CAS-22204-53-1
CCRIS 5265
CG 3117
CHEBI:7476
CHEMBL154
CID156391
Calosen
Clinosyn
Congex
D-Naproxen
DB08298
DL Naproxen
DL-Naproxen
Danaprox
Daprox
Diocodal
DivK1c_000242
Duk
Dysmenalgit
Dysmenalgit N
EINECS 244-838-7
Ec-Naprosyn
Equiproxen
Equiproxen (Veterinary)
FT-0082415
Flanax Forte
Flexen
Flexipen
Floginax
Fuxen
Genoxen
HMS1920P13
HMS2089N21
HMS2091H12
HMS500M04
HSDB 3369
Headlon
IDI1_000242
InChI=1/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
KBio1_000242
KBio2_001457
KBio2_004025
KBio2_006593
KBio3_001567
KBioGR_000597
KBioSS_001457
LS-124738
 
Laraflex
Lefaine
Leniartil
Lopac0_000792
M1021
Methoxypropiocin
MolPort-000-145-960
N8280_SIAL
NAPROXEN
NCGC00016759-01
NCGC00021127-01
NCGC00161591-01
NINDS_000242
NPS
Nafasol
Naixan
Nalyxan
Napflam
Napmel
Naposin
Napratec
Naprelan
Napren
Napren E
Naprius
Naprolag
Naprontag
Naprosin
Naprosyn LLE
Naprosyn LLE Forte
Naprosyne
Naproxen
Naproxen Sodium
Naproxen [USAN:BAN:INN:JAN]
Naproxene
Naproxene [INN-French]
Naproxeno
Naproxeno [INN-Spanish]
Naproxenum
Naproxenum [INN-Latin]
Naproxi 250
Naproxi 500
Naproxène
Napxen
Narma
Narocin
Naxen
Naxen F
Naxopren
Naxyn
Naxyn 250
Naxyn 500
Noflam
Novonaprox
Nycopren
Opipramol
Patxen
Prafena
Prestwick0_000791
Prestwick1_000791
Prestwick2_000791
Prestwick_349
Prexan
Priaxen
Pronaxen
Proxen LE
Proxen LLE
RS 3540
RS-3540
Rahsen
Reuxen
Rheumaflex
Roxen
SPBio_000966
SPBio_002861
SPECTRUM1500425
SR-01000075977-3
STOCK1N-50633
Saritilron
Sinartrin
Sinton
Soproxen
Spectrum2_001043
Spectrum3_000514
Spectrum4_000069
Spectrum5_001327
Spectrum_000977
Sutolin
Sutony
TL8003659
Tohexen
Traumox
U-Ritis
UNII-57Y76R9ATQ
UPCMLD-DP001
UPCMLD-DP001:001
Velsay
Veradol
Vinsen
Xenar
d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure
d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure [German]
d-2-(6-Methoxy-2-naphthyl)propionic acid
d-Naproxen
16
Aspirinapproved, vet_approvedPhase 4, Phase 2111250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
17
Ustekinumabapproved, investigationalPhase 4, Phase 3, Phase 282815610-63-0
Synonyms:
 
Stelera
18
AceclofenacapprovedPhase 41189796-99-6
Synonyms:
2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid
2-[(2,6-dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester
2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid
Aceclofenac
 
Aceclofenaco
Aceclofenacum
PR-82/3
acéclofénac
glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester
19
AlendronateapprovedPhase 4160121268-17-5, 66376-36-12088
Synonyms:
(4-Amino-1-hydroxybutylidene)bisphosphonic acid
(4-Amino-1-hydroxybutylidene)diphosphonic acid
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
(4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid)
(4-amino-1-hydroxybutylidene)bisphosphonic acid
121268-17-5 (mono-hydrochloride salt, trihydrate)
1yhm
4-Amino-1-hydroxybutane-1,1-diphosphonate
4-Amino-1-hydroxybutane-1,1-diphosphonic Acid
4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
4-amino-1-hydroxybutane-1,1-diphosphonic acid
66376-36-1
ABDP
AC1L1CW3
AKOS001015793
ALENDRONATE SODIUM
ALENDRONIC ACID
Acide Alendronique
Acide Alendronique [INN-French]
Acide alendronique
Acide alendronique [INN-French]
Acido Alendronico
Acido Alendronico [INN-Spanish]
Acido alendronico
Acido alendronico [INN-Spanish]
Acidum Alendronicum
Acidum Alendronicum [INN-Latin]
Acidum alendronicum
Acidum alendronicum [INN-Latin]
Adronat
 
Alendronate
Alendronate Sodium
Alendronate sodium hydrate
Alendronic acid
Alendronic acid (INN)
Alendronic acid [INN:BAN]
Alendros
Arendal
BIDD:GT0180
C07752
CHEBI:2567
CHEMBL870
CID2088
D07119
DB00630
Fosamax
Fosamax Plus D
HSCI1_000337
LS-106421
MK 217
MK-217
MolPort-000-421-410
NCGC00096054-01
NCGC00096054-03
NCGC00096054-04
Onclast
Oprea1_422906
Phosphonic acid, (4-amino-1-hydroxybutylidene)bis
SPECTRUM1505166
ST50036159
UNII-X1J18R4W8P
alendronate
bisphosphonate, 65
20
IbuprofenapprovedPhase 450115687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
 
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
21
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 3, Phase 2, Phase 1427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
22Folic Acid AntagonistsPhase 4, Phase 3, Phase 2, Phase 12200
23Antibodies, MonoclonalPhase 4, Phase 3, Phase 2, Phase 13795
24AntimetabolitesPhase 4, Phase 3, Phase 2, Phase 111774
25Vitamin B ComplexPhase 4, Phase 3, Phase 2, Phase 14229
26Nucleic Acid Synthesis InhibitorsPhase 4, Phase 3, Phase 2, Phase 14855
27Antimetabolites, AntineoplasticPhase 4, Phase 3, Phase 2, Phase 17171
28Dermatologic AgentsPhase 4, Phase 3, Phase 2, Phase 15674
29Gastrointestinal AgentsPhase 4, Phase 2, Phase 3, Phase 18109
30Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 112770
31Natriuretic Peptide, BrainPhase 4178
32Antirheumatic AgentsPhase 4, Phase 2, Phase 3, Phase 110627
33Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 2, Phase 3, Phase 14295
34AnalgesicsPhase 4, Phase 2, Phase 3, Phase 111287
35Analgesics, Non-NarcoticPhase 4, Phase 2, Phase 3, Phase 16260
36Anti-Inflammatory AgentsPhase 4, Phase 2, Phase 3, Phase 110355
37Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 122776
38Natriuretic AgentsPhase 41645
39beta-endorphinPhase 4133
40Melanocyte-Stimulating HormonesPhase 4132
41Hormone AntagonistsPhase 4, Phase 2, Phase 312778
42Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 2, Phase 312767
43Adrenocorticotropic HormonePhase 4155
44VaccinesPhase 4, Phase 26428
45AntibodiesPhase 4, Phase 3, Phase 2, Phase 16045
46ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16045
47Anti-Infective AgentsPhase 4, Phase 2, Phase 321402
48HormonesPhase 4, Phase 2, Phase 313979
49Antibiotics, AntitubercularPhase 4, Phase 36972
50Angiogenesis InhibitorsPhase 4, Phase 3, Phase 24143

Interventional clinical trials:

(show top 50)    (show all 399)
idNameStatusNCT IDPhase
1Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF BlockerUnknown statusNCT01072058Phase 4
2Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing SpondylitisUnknown statusNCT02132234Phase 4
3Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative ArthritisUnknown statusNCT00573651Phase 4
4Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic DiseasesUnknown statusNCT01151644Phase 4
5Protocol for H.P. Acthar Gel in Moderately to Severely Active Psoriatic ArthritisUnknown statusNCT01939132Phase 4
6Study Evaluating Etanercept and Sulphasalazine in Ankylosing SpondylitisCompletedNCT00247962Phase 4
7Study Evaluating Etanercept in Subjects With Ankylosing Spondylitis in SpainCompletedNCT00873730Phase 4
8Study Evaluating Etanercept for the Treatment of Active, Severe, and Advanced Axial Ankylosing SpondylitisCompletedNCT00420238Phase 4
9Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS)CompletedNCT01895764Phase 4
10Study Evaluating Etanercept in Patients With Ankylosing SpondylitisCompletedNCT00458185Phase 4
11An Open-Label Multicentre Long-Term Extension Study of Etanercept for Ankylosing SpondylitisCompletedNCT00444340Phase 4
12A Study Of Celecoxib Versus Diclofenac In Patients With Ankylosing SpondylitisCompletedNCT02528201Phase 4
13Work Productivity in Active Ankylosing Spondylitis (AS) Patients Treated With Enbrel.CompletedNCT01421303Phase 4
14Analysis of the Peripheral Blood Mononuclear Cells of Patients With Ankylosing Spondylitis During Infliximab Treatment (Study P04465)(COMPLETED)CompletedNCT00778869Phase 4
15A Study of the Efficacy and Tolerance of Remicade in the Treatment of Active Ankylosing Spondylitis (Study P04042)(COMPLETED)CompletedNCT00779012Phase 4
16Growth Factor Concentration to Predict an Ankylosing Spondylitis Patient's Response to Infliximab (Study P04041)(COMPLETED)CompletedNCT00779935Phase 4
17The Incidence of Extra-Articular Manifestations in Participants With Ankylosing Spondylitis Treated With Golimumab (MK-8259-012)CompletedNCT01668004Phase 4
18Relapse of Ankylosing Spondylitis Patients Withdrawal Etanercept After Clinical Remission: a Following-up StudyCompletedNCT02915354Phase 4
19Study Investigating Enbrel Treatment for Ankylosing SpondylitisCompletedNCT00195416Phase 4
20Extension Study Evaluating Etanercept in Ankylosing SpondylitisCompletedNCT00410046Phase 4
21Study Evaluating The Use Of Etanercept In Patients With Ankylosing SpondylitisCompletedNCT00544557Phase 4
22Infliximab and Methotrexate in Ankylosing SpondylitisCompletedNCT00507403Phase 4
23Efficacy and Safety of Kunxian Capsule in Treatment Patients With Early Ankylosing SpondylitisCompletedNCT00953979Phase 4
24Treatment With Alendronate in Patients With Ankylosing Spondylitis (AS)CompletedNCT01104987Phase 4
25Effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) on RAdiographic Damage in Ankylosing SpondylitisCompletedNCT00715091Phase 4
26Effect of Anti-TNF (Alpha) Treatment on Vascular Stiffness in Ankylosing Spondylitis (AS)CompletedNCT01212653Phase 4
27Combination Methotrexate and InfliximabCompletedNCT00432432Phase 4
28Efficacy and Safety Study of Infliximab (Remicade) to Treat Early Ankylosing SpondylitisCompletedNCT00936143Phase 4
29An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis ParticipantsCompletedNCT00760669Phase 4
30Tramadol/Acetaminophen(Ultracet) AS add-on Therapy in the Treatment of Patients With Ankylosing SpondylitisCompletedNCT00647517Phase 4
31Total Glucosides Paeony Capsules in Maintaining Clinical Remission in Patients With Ankylosing Spondylitis Which Achieve Clinical Remission After Anti-TNF TherapyCompletedNCT01517620Phase 4
32Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal HealingCompletedNCT01174186Phase 4
33Post Marketing Surveillance of RemicadeCompletedNCT00724529Phase 4
34TNFalfa Blocking Treatment of SpondylarthropathiesCompletedNCT00133315Phase 4
35Evaluation of a Protocol for Dose Reduction in Patients With Spondylarthropathies and Clinical Remission With Anti-TNFCompletedNCT01604629Phase 4
36Adalimumab in Axial Spondyloarthritis (ASIM) - MRI and Biomarkers in Patients With SpondyloarthritisCompletedNCT01029847Phase 4
37Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week TrialCompletedNCT01718951Phase 4
38A Study to Evaluate the NSAIDS Sparing Effect of Etanercept in Subjects With Axial SpondyloarthritisCompletedNCT01298531Phase 4
39A Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With SpondyloarthritisCompletedNCT02960035Phase 4
40Prevalence of Psoriatic Arthritis in Adults With Psoriasis: An Estimate From Dermatology PracticeCompletedNCT01147874Phase 4
41Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic ArthritisCompletedNCT00432406Phase 4
42A Study in Participants With Psoriatic Arthritis Attending Dermatology ClinicsCompletedNCT02470481Phase 4
43Centocor Microarray Study of PatientsCompletedNCT00462072Phase 4
44HUmira in Psoriatic ArthritisCompletedNCT01465438Phase 4
45Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic ArthritisCompletedNCT00245960Phase 4
46An Observational Study of Infliximab in Participants Suffering From Ankylosing Spondylitis With Hip InvolvementRecruitingNCT02293681Phase 4
47The Effect of NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in the Spine in Ankylosing SpondylitisRecruitingNCT02758782Phase 4
48A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab (AIN457) to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients With Ankylosing SpondylitRecruitingNCT02763046Phase 4
49Biomarkers Identification of Anti-tumor Necrosis Factor (TNF) α Agent's Efficacy in Ankylosing Spondylitis PatientsRecruitingNCT02492217Phase 4
50Tracking Biologics Along the Silk RoadRecruitingNCT03006198Phase 4

Search NIH Clinical Center for Spondyloarthropathy 1

Inferred drug relations via UMLS67/NDF-RT45:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Spondyloarthropathy 1 cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Spondyloarthropathy 1:
Umbilical cord-derived mesenchymal stem cells to treat ankylosing spondylitis
Embryonic/Adult Cultured Cells Related to Spondyloarthropathy 1:
Umbilical cord-derived mesenchymal stem cells (family)
Placenta-derived mesenchymal stem cells (family)


Cochrane evidence based reviews: spondylitis, ankylosing

Genetic Tests for Spondyloarthropathy 1

About this section

Genetic tests related to Spondyloarthropathy 1:

id Genetic test Affiliating Genes
1 Ankylosing Spondylitis26
2 Spondyloarthropathy 1, Susceptibility to24

Anatomical Context for Spondyloarthropathy 1

About this section

MalaCards organs/tissues related to Spondyloarthropathy 1:

35
Bone, Skin, Testes, Heart, Eye, Lung, Endothelial

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Spondyloarthropathy 1:
id TissueAnatomical CompartmentCell Relevance
1 PlacentaChorionic VillusChorionic Mesenchymal Stromal Cells Potential therapeutic candidate
2 Umbilical CordWharton's JellyMesenchymal Stem Cells Potential therapeutic candidate
3 BloodCord BloodMesenchymal Stem Cells Potential therapeutic candidate

Animal Models for Spondyloarthropathy 1 or affiliated genes

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MGI Mouse Phenotypes related to Spondyloarthropathy 1:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.5ANKH, IL17A, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
2MP:00053766.7ANKH, CD40LG, CD79A, CRP, IL17A, IL1RN
3MP:00053906.6ANKH, CD40LG, IL17A, IL1RN, MMP3, NOD2
4MP:00053976.2ANKH, CD40LG, CD79A, IL17A, IL1RN, MMP3
5MP:00053875.9ANKH, CD40LG, CD79A, CRP, IL17A, IL1RN

Publications for Spondyloarthropathy 1

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Variations for Spondyloarthropathy 1

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Clinvar genetic disease variations for Spondyloarthropathy 1:

5
id Gene Variation Type Significance SNP ID Assembly Location
1HLA-BHLA-B, HLA-B27undetermined variantrisk factorChr na, -1: -1

Expression for genes affiliated with Spondyloarthropathy 1

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Search GEO for disease gene expression data for Spondyloarthropathy 1.

Pathways for genes affiliated with Spondyloarthropathy 1

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Pathways related to Spondyloarthropathy 1 according to GeneCards Suite gene sharing:

(show all 24)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5TNF, TNFRSF1A, TNFRSF1B
29.5TNF, TNFRSF1A, TNFRSF1B
39.5TNF, TNFRSF1A, TNFRSF1B
4
Show member pathways
9.5TNF, TNFRSF1A, TNFRSF1B
59.5TNF, TNFRSF1A, TNFRSF1B
69.4CD40LG, TNFRSF1A, TNFRSF1B
79.4NOD2, TNF, TNFRSF1A
89.3TNFRSF11B, TNFSF11
99.3TNFRSF11B, TNFSF11
10
Show member pathways
9.0TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
119.0IL17A, MMP3, TNF, TNFSF11
12
Show member pathways
8.9CD40LG, CD79A, TNF, TNFRSF1A, TNFRSF1B
138.9CD40LG, IL17A, TNF, TNFSF11
148.9MMP3, NOD2, TNF, TNFRSF1A, TNFRSF1B
158.8CD40LG, TNF, TNFRSF1A, TNFSF11
168.8CD40LG, TNFRSF1A, TNFRSF1B, TNFSF11
17
Show member pathways
8.7CD40LG, HLA-B, IL17A, NOD2, TAPBP, TNF
188.7BGLAP, TNF, TNFRSF11B, TNFSF11
198.6TNF, TNFRSF11B, TNFRSF1A, TNFSF11
20
Show member pathways
8.5CD40LG, TNF, TNFRSF1A, TNFRSF1B, TNFSF11
21
Show member pathways
8.0CD40LG, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFSF11
22
Show member pathways
8.0CD40LG, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFSF11
237.5CD40LG, CD79A, IL1RN, TNF, TNFRSF1A, TNFRSF1B
24
Show member pathways
5.5CD40LG, CD79A, CRP, HLA-B, IL17A, IL1RN

GO Terms for genes affiliated with Spondyloarthropathy 1

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Cellular components related to Spondyloarthropathy 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.7CD40LG, CD79A, IL17A, TNF
2membrane raftGO:00451219.5CD79A, TNF, TNFRSF1A, TNFRSF1B
3cell surfaceGO:00099869.1CD40LG, HLA-B, NOD2, TNF, TNFRSF1A
4integral component of plasma membraneGO:00058877.5ANKH, CD40LG, CD79A, TNF, TNFRSF11B, TNFRSF1A
5extracellular regionGO:00055766.4BGLAP, CRP, IL17A, IL1RN, MMP3, TNF
6extracellular spaceGO:00056156.2BGLAP, CD40LG, CRP, IL17A, IL1RN, MMP3
7plasma membraneGO:00058865.4ANKH, CD40LG, CD79A, HLA-B, IL1RN, MRAP

Biological processes related to Spondyloarthropathy 1 according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipid storageGO:001088810.6CRP, TNF
2positive regulation of NIK/NF-kappaB signalingGO:190122410.5NOD2, TNF
3regulation of immunoglobulin secretionGO:005102310.5CD40LG, TNF
4regulation of establishment of endothelial barrierGO:190314010.4TNF, TNFRSF1A
5positive regulation of cytokine production involved in inflammatory responseGO:190001710.3IL17A, NOD2
6death-inducing signaling complex assemblyGO:007155010.3TNF, TNFRSF1A
7positive regulation of ceramide biosynthetic processGO:200030410.2TNF, TNFRSF1A
8intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.0TNF, TNFRSF1A, TNFRSF1B
9positive regulation of JNK cascadeGO:00463309.8NOD2, TNF, TNFSF11
10positive regulation of osteoclast differentiationGO:00456729.8IL17A, TNF, TNFSF11
11regulation of osteoclast differentiationGO:00456709.7BGLAP, TNF, TNFSF11
12defense responseGO:00069529.6NOD2, TNF, TNFRSF1A
13response to glucocorticoidGO:00513849.5BGLAP, IL1RN, TNF
14positive regulation of NF-kappaB transcription factor activityGO:00510929.3CD40LG, NOD2, TNF, TNFSF11
15positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.2NOD2, TNF, TNFRSF1A, TNFSF11
16apoptotic signaling pathwayGO:00971909.2TNF, TNFRSF11B, TNFRSF1B
17regulation of cell proliferationGO:00421279.0TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
18tumor necrosis factor-mediated signaling pathwayGO:00332098.6CD40LG, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFSF11
19inflammatory responseGO:00069548.0CD40LG, CRP, IL17A, TNF, TNFRSF11B, TNFRSF1A
20immune responseGO:00069557.0IL17A, IL1RN, TAPBP, TNFRSF11B, TNFRSF1A, TNFRSF1B

Molecular functions related to Spondyloarthropathy 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.7CD40LG, TNF, TNFSF11
2tumor necrosis factor-activated receptor activityGO:00050319.6TNFRSF11B, TNFRSF1A, TNFRSF1B
3cytokine activityGO:00051257.6CD40LG, IL17A, IL1RN, TNF, TNFRSF11B, TNFSF11

Sources for Spondyloarthropathy 1

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet