Aliases & Classifications for Spondylolisthesis

Aliases & Descriptions for Spondylolisthesis:

Name: Spondylolisthesis 38 12 29 52 42 14 69

Characteristics:

HPO:

32
spondylolisthesis:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:6682
ICD10 33 M43.1 M43.10
MeSH 42 D013168
NCIt 47 C35033
UMLS 69 C0038016

Summaries for Spondylolisthesis

Disease Ontology : 12 A bone structure disease that has material basis in displacement located in set of vertebrae.

MalaCards based summary : Spondylolisthesis is related to jaffer beighton syndrome and spondylolysis, and has symptoms including spondylolysis, spondylolisthesis at l5-s1 and back pain. An important gene associated with Spondylolisthesis is GDF5 (Growth Differentiation Factor 5), and among its related pathways/superpathways are Degradation of the extracellular matrix and Hippo signaling pathway. The drugs Ketamine and Oxycodone have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and set of vertebrae, and related phenotypes are immune system and nervous system

Wikipedia : 71 Spondylolisthesis /ˌspɒndᵻloʊlᵻsˈθiːsᵻs/ SPON-dill-oh-lis-THEE-sis is the forward or... more...

Related Diseases for Spondylolisthesis

Diseases related to Spondylolisthesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
id Related Disease Score Top Affiliating Genes
1 jaffer beighton syndrome 10.8
2 spondylolysis 10.7
3 spinal stenosis 10.4
4 cervicitis 10.3
5 back pain 10.2
6 hemolytic anemia due to glutathione synthetase deficiency 10.2 GDF5 MMP3
7 scoliosis 10.2
8 cardiomyopathy, dilated, 1g 10.2 ESR1 FTH1
9 chondrodysplasia punctata, rhizomelic, type 1 10.1 MMP3 PTGS2
10 pulmonary fibrosis 10.1 BMP2 BMP7
11 immunodeficiency, common variable, 12 10.1 BMP2 GDF5
12 immune system disease 10.1 ESR1 MMP3 PTGS2
13 adult neuronal ceroid lipofuscinosis 10.1 ESR1 PTGS2
14 bronchus cancer 10.1 BMP2 GDF5
15 osteonecrosis 10.1 GDF5 MMP3 PTGS2
16 acth-independent macronodular adrenal hyperplasia 10.0 BMP2 BMP7
17 tarsal-carpal coalition syndrome 10.0 BMP2 BMP7 GDF5
18 multiple synostoses syndrome 10.0 BMP2 BMP7 GDF5
19 degenerative disc disease 10.0
20 acrocephalopolydactylous dysplasia 10.0 BMP2 ESR1
21 spina bifida occulta 9.9
22 spondylosis 9.9
23 epidermolysis bullosa acquisita 9.9 BMP2 IVD
24 nocardiosis 9.9 BMP7 FTH1 GDF5 PGRMC1
25 neurofibromatosis 9.8
26 idiopathic scoliosis 9.8
27 discitis 9.8
28 cauda equina syndrome 9.8
29 osteoarthritis 9.8
30 radiculopathy 9.8
31 adolescent idiopathic scoliosis 9.7
32 obesity 9.7
33 osteogenesis imperfecta 9.7
34 dentin dysplasia 9.7 BMP2 GDF5 IVD MMP3
35 fibromatosis 9.6
36 osteomyelitis 9.6
37 rheumatoid arthritis 9.6
38 pycnodysostosis 9.6
39 osteoporosis 9.6
40 gout 9.6
41 rubinstein-taybi syndrome 9.6
42 ehlers-danlos syndrome 9.6
43 arthritis 9.6
44 cerebral palsy 9.6
45 basal cell carcinoma 9.6
46 pseudoarthrosis 9.6
47 cerebritis 9.6
48 tuberculosis 9.6
49 inflammatory myofibroblastic tumor 9.6
50 bone resorption disease 9.4 BMP2 BMP7 FTH1 GDF5 IVD MMP3

Graphical network of the top 20 diseases related to Spondylolisthesis:



Diseases related to Spondylolisthesis

Symptoms & Phenotypes for Spondylolisthesis

Human phenotypes related to Spondylolisthesis:

32
id Description HPO Frequency HPO Source Accession
1 spondylolysis 32 HP:0003304
2 spondylolisthesis at l5-s1 32 HP:0008489

UMLS symptoms related to Spondylolisthesis:


back pain

MGI Mouse Phenotypes related to Spondylolisthesis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.8 BMP2 BMP7 ESR1 FTH1 IDS MMP3
2 nervous system MP:0003631 9.56 MMP3 PGRMC1 PTGS2 BMP2 BMP7 ESR1
3 limbs/digits/tail MP:0005371 9.55 BMP2 BMP7 ESR1 GDF5 IDS
4 skeleton MP:0005390 9.17 BMP2 BMP7 ESR1 GDF5 IDS MMP3

Drugs & Therapeutics for Spondylolisthesis

Drugs for Spondylolisthesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
2
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
3
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
4 Calcium, Dietary Phase 4,Phase 2
5
s 1 (combination) Phase 4,Phase 1,Phase 2
6 Analgesics Phase 4,Phase 2,Phase 3
7 Analgesics, Opioid Phase 4
8 Anesthetics Phase 4,Phase 2,Phase 3
9 Anesthetics, Dissociative Phase 4
10 Anesthetics, General Phase 4
11 Anesthetics, Intravenous Phase 4
12 Central Nervous System Depressants Phase 4,Phase 2,Phase 3
13 Excitatory Amino Acid Antagonists Phase 4
14 Excitatory Amino Acids Phase 4
15 Narcotics Phase 4
16 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
17 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
18 Anti-Anxiety Agents Phase 4
19 Anticonvulsants Phase 4
20 calcium channel blockers Phase 4
21 Psychotropic Drugs Phase 4
22 Tranquilizing Agents Phase 4
23
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
24 Adrenergic Agents Phase 2, Phase 3
25 Adrenergic Agonists Phase 2, Phase 3
26 Adrenergic alpha-2 Receptor Agonists Phase 2, Phase 3
27 Adrenergic alpha-Agonists Phase 2, Phase 3
28 Analgesics, Non-Narcotic Phase 2, Phase 3
29 Hypnotics and Sedatives Phase 2, Phase 3
30
Menthol Approved Phase 2 2216-51-5 16666
31
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
32
Propofol Approved, Investigational, Vet_approved Phase 2 2078-54-8 4943
33
Remifentanil Approved Phase 2 132875-61-7 60815
34
Ropivacaine Approved Phase 2 84057-95-4 71273 175805
35 BB 1101 Phase 2
36 Dexamethasone 21-phosphate Phase 2
37 Dexamethasone acetate Phase 2 1177-87-3
38 Anesthetics, Local Phase 2
39 Cisatracurium Phase 2
40
Mepivacaine Approved, Vet_approved 96-88-8 4062
41
Benzocaine Approved 1994-09-7, 94-09-7 2337
42
Bupivacaine Approved, Investigational 2180-92-9, 38396-39-3 2474
43
Epinephrine Approved, Vet_approved 51-43-4 5816
44
Ketorolac Approved 74103-06-3, 66635-83-4 3826
45
Lidocaine Approved, Vet_approved 137-58-6 3676
46
Morphine Approved, Investigational 57-27-2 5288826
47
Dimenhydrinate Approved 523-87-5 441281
48
Teriparatide Approved, Investigational 52232-67-4 16133850
49
Gabapentin Approved, Investigational 60142-96-3 3446
50 tannic acid Approved, Nutraceutical

Interventional clinical trials:

(show top 50) (show all 124)
id Name Status NCT ID Phase
1 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
2 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4
3 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
4 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
5 Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation Completed NCT00000410 Phase 4
6 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
7 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
8 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4
9 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
10 Comparison of the Aspen Device Versus Pedicle Screws for Supplemental Posterior Fixation in Lumbar Interbody Fusion Recruiting NCT01549366 Phase 4
11 Post-Market Surveillance Study of the TM Ardis Interbody Fusion System Active, not recruiting NCT02429908 Phase 4
12 Comparison of Complication Rates Between Lateral Approaches to the Lumbar Spine Enrolling by invitation NCT02068729 Phase 4
13 Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis Terminated NCT01560273 Phase 4
14 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
15 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
16 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
17 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
18 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
19 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Recruiting NCT02854904 Phase 2, Phase 3
20 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis Active, not recruiting NCT01618435 Phase 3
21 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
22 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
23 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
24 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
25 Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow Unknown status NCT01335243 Phase 2
26 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
27 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
29 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
30 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
31 Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion Recruiting NCT02205138 Phase 2
32 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
33 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Not yet recruiting NCT02884440 Phase 2
34 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
35 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
36 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766
37 Effects of Exercise Intervention on Patients With Low Back Pain Due to Spondylolytic Spondylolisthesis. Unknown status NCT01985776
38 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473
39 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379
40 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
41 Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion Unknown status NCT02317185
42 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
43 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284
44 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
45 Luna Interbody System for Fusion Trial Unknown status NCT01551901
46 XLIF® vs. MAS®TLIF for the Treatment of Symptomatic Lumbar Degenerative Spondylolisthesis With or Without Central Stenosis. Completed NCT01024699
47 The Addition of a Pilates Program for Short-Term Improvements in Patients With Spondylolysis or Spondylolisthesis Completed NCT01711203
48 Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability Completed NCT00726310
49 SPONGIT: Comparison of Two Surgical Approaches in the Treatment of Degenerative Spondylolysthesis Completed NCT00869882
50 Spinal Fusion and Rehabilitation Study Completed NCT00834015

Search NIH Clinical Center for Spondylolisthesis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Spondylolisthesis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Spondylolisthesis:
MPCs, mesenchymal precursor cells for bone fusion
Embryonic/Adult Cultured Cells Related to Spondylolisthesis:
Mesenchymal Precursor Cells (STRO-3 selected) PMIDs: 24438940 20528753

Cochrane evidence based reviews: spondylolisthesis

Genetic Tests for Spondylolisthesis

Genetic tests related to Spondylolisthesis:

id Genetic test Affiliating Genes
1 Spondylolisthesis 29

Anatomical Context for Spondylolisthesis

MalaCards organs/tissues related to Spondylolisthesis:

39
Bone, Testes

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylolisthesis:

18
Set Of Vertebrae

Publications for Spondylolisthesis

Articles related to Spondylolisthesis:

(show top 50) (show all 739)
id Title Authors Year
1
Degenerative spondylolisthesis: contemporary review of the role of interbody fusion. ( 27888353 )
2017
2
Responsiveness of the bridge maneuvers in subjects with symptomatic lumbar spondylolisthesis: A prospective cohort study. ( 28060461 )
2017
3
Segmental polymethylmethacrylate-augmented fenestrated pedicle screw fixation for lumbar spondylolisthesis in patients with osteoporosis - A case series and review of literature. ( 28084247 )
2017
4
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial. ( 28072709 )
2017
5
Congenital hypoplasia of the lumbar pedicle with spondylolisthesis: report of 2 cases. ( 28059687 )
2017
6
Resolution of the more anteriorly positioned psoas muscle following correction of spinal sagittal alignment from spondylolisthesis: case report. ( 28059685 )
2017
7
Posterolateral Fusion Versus Interbody Fusion for Degenerative Spondylolisthesis: A Systematic Review and Meta-Analysis. ( 27105465 )
2016
8
Efficacy of transsacral instrumentation for high-grade spondylolisthesis at L5-S1: A systematic review of the literature. ( 27216924 )
2016
9
Surgical treatment of degenerative spondylolisthesis. ( 28043848 )
2016
10
South Korean degenerative spondylolisthesis patients had surgical treatment at earlier age than Japanese, American, and European patients: a published literature observation. ( 28090453 )
2016
11
The effectiveness of decompression alone compared with additional fusion for lumbar spinal stenosis with degenerative spondylolisthesis: a pragmatic comparative non-inferiority observational study from the Norwegian Registry for Spine Surgery. ( 27421276 )
2016
12
Posterolateral instrumented fusion with and without transforaminal lumbar interbody fusion for the treatment of adult isthmic spondylolisthesis: A randomized clinical trial with 2-year follow-up. ( 27041885 )
2016
13
Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy With Degenerative Spondylolisthesis. ( 27213938 )
2016
14
Return of motor evoked potentials after knee flexion in the setting of high-grade spondylolisthesis. ( 27858240 )
2016
15
Critical Values of Facet Joint Angulation and Tropism in the Development of Lumbar Degenerative Spondylolisthesis: An International, Large-Scale Multicenter Study by the AOSpine Asia Pacific Research Collaboration Consortium. ( 27433424 )
2016
16
Degenerative Spondylolisthesis in the Fifth Lumbar Vertebra and Radiographic Parameters: A Correlation Analysis. ( 27623300 )
2016
17
Sagittal spinopelvic parameters in 2-level lumbar degenerative spondylolisthesis: A retrospective study. ( 27977581 )
2016
18
Patient-reported and radiographic outcomes of minimally invasive transforaminal lumbar interbody fusion for degenerative spondylolisthesis with or without reduction: A comparative study. ( 27443498 )
2016
19
Neurogenic claudication secondary to degenerative spondylolisthesis: is fusion always necessary? ( 27437763 )
2016
20
Transforaminal lumbar interbody fusion versus instrumented posterolateral fusion In degenerative spondylolisthesis: An attempt to evaluate the superiority of one method over the other. ( 27565009 )
2016
21
Current Status of Lumbar Interbody Fusion for Degenerative Spondylolisthesis. ( 27169496 )
2016
22
A Novel Motion-Preservation Technique for Intra and Intra-Intersegmental Repair of Spondylolysis and Spondylolisthesis: The Lin Technique. ( 27608745 )
2016
23
Dynamic Radiographic Results of Different Semi-Rigid Fusion Devices for Degenerative Lumbar Spondylolisthesis: "Dynamic Rod" vs. "Dynamic Screw Head". ( 26956824 )
2016
24
One-Level Lumbar Degenerative Spondylolisthesis And Posterior Approach. Is Transforaminal Lateral Interbody Fusion Mandatory? A Randomized Controlled Trial With Two Year Follow-Up. ( 27548582 )
2016
25
Radiological Evaluation of the Initial Fixation between Cortical Bone Trajectory and Conventional Pedicle Screw Technique for Lumbar Degenerative Spondylolisthesis. ( 27114765 )
2016
26
Influence of Sacral Slope on the Loading of Pedicle Screws in Postoperative L5/S1 Isthmic Spondylolisthesis Patient: A Finite Element Analysis. ( 27898599 )
2016
27
Increased Segmental Range of Motion is Correlated with Spondylolisthesis in the Cervical Spine after Laminoplasty. ( 27488291 )
2016
28
Post-Operative Complications for Elderly Patients after Single-Level Lumbar Fusions for Spondylolisthesis. ( 27020975 )
2016
29
Guideline summary review: an evidence-based clinical guideline for the diagnosis and treatment of adult isthmic spondylolisthesis. ( 27592807 )
2016
30
Short-Term Clinical Result of Cortical Bone Trajectory Technique for the Treatment of Degenerative Lumbar Spondylolisthesis with More than 1-Year Follow-Up. ( 27114763 )
2016
31
Burst C2 Fractures Combined with Traumatic Spondylolisthesis: Can Atlantoaxial Motion Be Preserved? Including Some Technical Tips for Reduction and Fixation. ( 27555997 )
2016
32
Can facet joint fluid on MRI and dynamic instability be a predictor of improvement in back pain following lumbar fusion for degenerative spondylolisthesis? ( 27106489 )
2016
33
Cost-Effectiveness of Lumbar Spondylolisthesis Surgery at 2-Year Follow-up. ( 27852500 )
2016
34
A novel technique to repair a transverse sacral fracture in a previously fused lumbosacral spondylolisthesis. ( 28028448 )
2016
35
Congenital Spondylolytic Spondylolisthesis of C2 Vertebra Associated With Atlanto-Axial Dislocation, Chiari Type I Malformation, and Anomalous Vertebral Artery: Case Report With Review Literature. ( 27535630 )
2016
36
Minimally invasive surgery for lumbar synovial cysts with coexisting degenerative spondylolisthesis. ( 27909658 )
2016
37
Mobilisation of the thoracic spine in the management of spondylolisthesis. ( 27634084 )
2016
38
National Trends in the Surgical Management of Adult Lumbar Isthmic Spondylolisthesis: 1998 to 2011. ( 26966973 )
2016
39
Can physical therapy centred on cognitive and behavioural principles improve pain self-efficacy in symptomatic lumbar isthmic spondylolisthesis? A case series. ( 27634078 )
2016
40
Reduction and circumferential fusion for low-grade slips and intermediate-grade slips in pediatric spondylolisthesis. ( 27392304 )
2016
41
Transdiscal screw versus pedicle screw fixation for high-grade L5-S1 isthmic spondylolisthesis in patients younger than 60A years: a case-control study. ( 27048540 )
2016
42
Classification of spondylolytic clefts in patients with spondylolysis or isthmic spondylolisthesis using positional MRI. ( 26987671 )
2016
43
Lumbar Degenerative Spondylolisthesis: Changes in Surgical Indications and Comparison of Instrumented Fusion with Two Surgical Decompression Procedures. ( 27196020 )
2016
44
The effects of muscle weakness on degenerative spondylolisthesis: A finite element study. ( 27918892 )
2016
45
Fusion for Lumbar Stenosis With Spondylolisthesis: Results From 2 Randomized Trials. ( 27428640 )
2016
46
Operative management of high-grade dysplastic L5 spondylolisthesis with the use of external transpedicular fixation: advantages and drawbacks. ( 26995744 )
2016
47
Laminectomy plus Fusion versus Laminectomy Alone for Lumbar Spondylolisthesis. ( 27074067 )
2016
48
Randomized controlled trials for degenerative lumbar spondylolisthesis: which patients benefit from lumbar fusion? ( 27661562 )
2016
49
Review of Pediatric Spondylolysis and Spondylolisthesis. ( 27811518 )
2016
50
Mini-invasive Transforaminal Lumbar Interbody Fusion through Wiltse Approach to Treating Lumbar Spondylolytic Spondylolisthesis. ( 27028380 )
2016

Variations for Spondylolisthesis

Expression for Spondylolisthesis

Search GEO for disease gene expression data for Spondylolisthesis.

Pathways for Spondylolisthesis

GO Terms for Spondylolisthesis

Biological processes related to Spondylolisthesis according to GeneCards Suite gene sharing:

(show all 20)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.8 BMP2 BMP7 FTH1 PTGS2
2 regulation of apoptotic process GO:0042981 9.74 BMP7 ESR1 GDF5
3 response to estradiol GO:0032355 9.65 BMP7 ESR1 PTGS2
4 positive regulation of neuron differentiation GO:0045666 9.61 BMP2 BMP7 GDF5
5 positive regulation of cell differentiation GO:0045597 9.59 BMP2 BMP7
6 positive regulation of cell death GO:0010942 9.58 BMP7 PTGS2
7 chondrocyte differentiation GO:0002062 9.58 BMP2 GDF5
8 cartilage development GO:0051216 9.58 BMP2 BMP7 GDF5
9 epithelial to mesenchymal transition GO:0001837 9.56 BMP2 BMP7
10 cellular response to BMP stimulus GO:0071773 9.55 BMP2 BMP7
11 bone mineralization GO:0030282 9.54 BMP2 PTGS2
12 positive regulation of bone mineralization GO:0030501 9.52 BMP2 BMP7
13 response to vitamin D GO:0033280 9.51 BMP7 PTGS2
14 SMAD protein signal transduction GO:0060395 9.5 BMP2 BMP7 GDF5
15 mesenchymal cell differentiation GO:0048762 9.46 BMP2 BMP7
16 regulation of branching involved in prostate gland morphogenesis GO:0060687 9.37 BMP7 ESR1
17 cell development GO:0048468 9.33 BMP2 BMP7 GDF5
18 mesenchyme development GO:0060485 9.26 BMP2 BMP7
19 positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 9.13 BMP2 BMP7 GDF5
20 negative regulation of cell cycle GO:0045786 8.8 BMP2 BMP7 PTGS2

Molecular functions related to Spondylolisthesis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.5 BMP2 BMP7 GDF5
2 growth factor activity GO:0008083 9.33 BMP2 BMP7 GDF5
3 steroid binding GO:0005496 9.26 ESR1 PGRMC1
4 BMP receptor binding GO:0070700 8.96 BMP2 BMP7
5 transforming growth factor beta receptor binding GO:0005160 8.8 BMP2 BMP7 GDF5

Sources for Spondylolisthesis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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