Aliases & Classifications for Spondylolisthesis

MalaCards integrated aliases for Spondylolisthesis:

Name: Spondylolisthesis 53 37 12 28 51 41 14 69

Characteristics:

OMIM:

53
Inheritance:
autosomal dominant


HPO:

31
spondylolisthesis:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 53 184200
Disease Ontology 12 DOID:6682
ICD10 32 M43.1 M43.10
MeSH 41 D013168
NCIt 46 C35033
MedGen 39 C0038016
SNOMED-CT via HPO 65 263681008 240221008
UMLS 69 C0038016

Summaries for Spondylolisthesis

OMIM : 53 Spondylolisthesis is defined as forward slipping of a vertebral body on the one below it. Spondylolysis is defined as a defect in the pars interarticularis without vertebral slipping (summary by Wiltse et al., 1975). (184200)

MalaCards based summary : Spondylolisthesis is related to spondylolysis and spinal stenosis, and has symptoms including spondylolysis, spondylolisthesis at l5-s1 and back pain. An important gene associated with Spondylolisthesis is BMP7 (Bone Morphogenetic Protein 7), and among its related pathways/superpathways are Degradation of the extracellular matrix and Hippo signaling pathway. The drugs Menthol and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include set of vertebrae, bone and bone marrow, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A bone structure disease that has material basis in displacement located in set of vertebrae.

Wikipedia : 72 Spondylolisthesis is the slippage or displacement of one vertebra compared to... more...

Related Diseases for Spondylolisthesis

Diseases related to Spondylolisthesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
# Related Disease Score Top Affiliating Genes
1 spondylolysis 31.1 BMP7 FTH1 GDF5
2 spinal stenosis 30.8 BMP7 MMP3
3 osteoarthritis 29.9 GDF5 MMP3 PTGS2
4 pseudoarthrosis 29.8 BMP2 BMP7
5 degenerative disc disease 29.5 BMP2 GDF5 IVD MMP3
6 jaffer beighton syndrome 11.0
7 episodic pain syndrome, familial, 1 10.4
8 adenomyosis 10.3 ESR1 PTGS2
9 cervicitis 10.3
10 endometrial disease 10.3 ESR1 PTGS2
11 cardiomyopathy, familial hypertrophic, 9 10.3 ESR1 FTH1
12 scoliosis 10.3
13 pelvic organ prolapse 10.3 ESR1 MMP3
14 back pain 10.3
15 brachydactyly, type a2 10.2 BMP2 GDF5
16 osteochondritis dissecans 10.2 BMP7 MMP3
17 osseous heteroplasia, progressive 10.1 BMP2 BMP7
18 endometriosis 10.1 ESR1 MMP3 PTGS2
19 shoulder impingement syndrome 10.1 PROS1 PTGS2
20 aging 10.1
21 polyradiculopathy 10.1 BMP2 IVD
22 bone resorption disease 10.0 BMP2 ESR1
23 proximal symphalangism 10.0 BMP2 BMP7 GDF5
24 neural tube defects 10.0
25 spina bifida occulta 10.0
26 spondylosis 10.0
27 bone mineral density quantitative trait locus 15 9.9
28 radiculopathy 9.9
29 juvenile polyposis syndrome 9.9 BMP2 PTGS2
30 neurofibromatosis, type iv, of riccardi 9.9
31 osteoarthritis with mild chondrodysplasia 9.9
32 idiopathic scoliosis 9.9
33 discitis 9.9
34 cauda equina syndrome 9.9
35 coronary artery aneurysm 9.8 MMP3 PRRC2A
36 bone remodeling disease 9.8 BMP2 ESR1
37 osteoporosis 9.8
38 polykaryocytosis inducer 9.8
39 scoliosis, isolated 1 9.8
40 body mass index quantitative trait locus 11 9.8
41 body mass index quantitative trait locus 9 9.8
42 body mass index quantitative trait locus 8 9.8
43 brittle bone disorder 9.8
44 body mass index quantitative trait locus 4 9.8
45 body mass index quantitative trait locus 10 9.8
46 body mass index quantitative trait locus 7 9.8
47 bone mineral density quantitative trait locus 8 9.8
48 body mass index quantitative trait locus 12 9.8
49 body mass index quantitative trait locus 14 9.8
50 body mass index quantitative trait locus 18 9.8

Graphical network of the top 20 diseases related to Spondylolisthesis:



Diseases related to Spondylolisthesis

Symptoms & Phenotypes for Spondylolisthesis

Symptoms via clinical synopsis from OMIM:

53
Spine:
spondylolisthesis of l5 on s1
defects in posterior spinous processes of l5 and sacrum
spondylolysis


Clinical features from OMIM:

184200

Human phenotypes related to Spondylolisthesis:

31
# Description HPO Frequency HPO Source Accession
1 spondylolysis 31 HP:0003304
2 spondylolisthesis at l5-s1 31 HP:0008489

UMLS symptoms related to Spondylolisthesis:


back pain

MGI Mouse Phenotypes related to Spondylolisthesis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.91 FTH1 BMP2 MMP3 PROS1 BMP7 PTGS2
2 immune system MP:0005387 9.87 FTH1 IDS BMP2 MMP3 BMP7 PTGS2
3 mortality/aging MP:0010768 9.81 GDF5 IDS IVD BMP2 PROS1 BMP7
4 limbs/digits/tail MP:0005371 9.65 GDF5 IDS BMP2 BMP7 ESR1
5 nervous system MP:0003631 9.56 IDS BMP2 MMP3 PROS1 BMP7 PTGS2
6 skeleton MP:0005390 9.17 GDF5 IDS BMP2 MMP3 BMP7 PTGS2

Drugs & Therapeutics for Spondylolisthesis

Drugs for Spondylolisthesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 60)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Menthol Approved Phase 4,Phase 2 2216-51-5 16666
2
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
3
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
4
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
5
s 1 (combination) Phase 4,Phase 1,Phase 2
6 Calcium, Dietary Phase 4,Phase 2
7 Analgesics Phase 4,Phase 2,Phase 3
8 Analgesics, Opioid Phase 4
9 Anesthetics Phase 4,Phase 2,Phase 3
10 Anesthetics, Dissociative Phase 4
11 Anesthetics, General Phase 4
12 Anesthetics, Intravenous Phase 4
13 Central Nervous System Depressants Phase 4,Phase 2,Phase 3
14 Excitatory Amino Acid Antagonists Phase 4
15 Excitatory Amino Acids Phase 4
16 Narcotics Phase 4
17 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
18 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
19 Anti-Anxiety Agents Phase 4
20 Anticonvulsants Phase 4
21 calcium channel blockers Phase 4
22 Psychotropic Drugs Phase 4
23 Tranquilizing Agents Phase 4
24
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3 76631-46-4, 113775-47-6 5311068 56032 68602
25 Adrenergic Agents Phase 2, Phase 3
26 Adrenergic Agonists Phase 2, Phase 3
27 Adrenergic alpha-2 Receptor Agonists Phase 2, Phase 3
28 Adrenergic alpha-Agonists Phase 2, Phase 3
29 Analgesics, Non-Narcotic Phase 2, Phase 3
30 Hypnotics and Sedatives Phase 2, Phase 3
31
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
32 Cisatracurium Approved, Experimental Phase 2 96946-41-7
33
Propofol Approved, Investigational, Vet_approved Phase 2 2078-54-8 4943
34
Remifentanil Approved Phase 2 132875-61-7 60815
35
Ropivacaine Approved Phase 2 84057-95-4 175805 71273
36 BB 1101 Phase 2
37 Dexamethasone acetate Phase 2 1177-87-3
38 Anesthetics, Local Phase 2
39
Teriparatide Approved, Investigational 52232-67-4 16133850
40
Mepivacaine Approved, Vet_approved 96-88-8 4062
41
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
42
Bupivacaine Approved, Investigational 38396-39-3, 2180-92-9 2474
43
Epinephrine Approved, Vet_approved 51-43-4 5816
44
Ketorolac Approved 74103-06-3, 66635-83-4 3826
45
Lidocaine Approved, Vet_approved 137-58-6 3676
46
Morphine Approved, Investigational 57-27-2 5288826
47 Racepinephrine Approved 329-65-7
48
Silicon Approved, Investigational 7440-21-3 4082203
49
Gabapentin Approved, Investigational 60142-96-3 3446
50
Dimenhydrinate Approved 523-87-5 441281

Interventional clinical trials:

(show top 50) (show all 137)

# Name Status NCT ID Phase Drugs
1 Comparison of the Aspen Device Versus Pedicle Screws for Supplemental Posterior Fixation in Lumbar Interbody Fusion Unknown status NCT01549366 Phase 4
2 Post-Market Surveillance Study of the TM Ardis Interbody Fusion System Unknown status NCT02429908 Phase 4
3 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
4 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
5 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
6 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
7 Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation Completed NCT00000410 Phase 4
8 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
9 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
10 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
11 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
12 Efficacy of Using Solum IV and BMC With GFC in TLIF Not yet recruiting NCT03223701 Phase 4
13 Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis Terminated NCT01560273 Phase 4
14 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
15 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
16 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
17 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
18 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
19 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Recruiting NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
20 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis Active, not recruiting NCT01618435 Phase 3
21 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
22 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
23 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
24 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
25 Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow Unknown status NCT01335243 Phase 2
26 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
27 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
29 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
30 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
31 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
32 Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion Recruiting NCT02205138 Phase 2 ALLOB® cells with ceramic scaffold
33 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
34 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
35 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
36 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766
37 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473
38 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379
39 Dynesys Spinal System Post Market 522 Study Unknown status NCT01528072
40 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
41 Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion Unknown status NCT02317185
42 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
43 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion Unknown status NCT01292252
44 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284
45 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
46 Luna Interbody System for Fusion Trial Unknown status NCT01551901
47 XLIF® vs. MAS®TLIF for the Treatment of Symptomatic Lumbar Degenerative Spondylolisthesis With or Without Central Stenosis. Completed NCT01024699
48 Effects of Exercise Intervention in Patients With Spondylolisthesis Related LBP Completed NCT01985776
49 The Addition of a Pilates Program for Short-Term Improvements in Patients With Spondylolysis or Spondylolisthesis Completed NCT01711203
50 Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability Completed NCT00726310

Search NIH Clinical Center for Spondylolisthesis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Spondylolisthesis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Spondylolisthesis:
MPCs, mesenchymal precursor cells for bone fusion
Embryonic/Adult Cultured Cells Related to Spondylolisthesis:
Mesenchymal Precursor Cells (STRO-3 selected) PMIDs: 24438940 20528753

Cochrane evidence based reviews: spondylolisthesis

Genetic Tests for Spondylolisthesis

Genetic tests related to Spondylolisthesis:

# Genetic test Affiliating Genes
1 Spondylolisthesis 28

Anatomical Context for Spondylolisthesis

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylolisthesis:

18
Set Of Vertebrae

MalaCards organs/tissues related to Spondylolisthesis:

38
Bone, Bone Marrow, Testes, Spinal Cord

Publications for Spondylolisthesis

Articles related to Spondylolisthesis:

(show top 50) (show all 780)
# Title Authors Year
1
How many physical therapy sessions are required to reach a good outcome in symptomatic lumbar spondylolisthesis? A retrospective study. ( 29332744 )
2018
2
Double-level isthmic spondylolisthesis treated with posterior lumbar interbody fusion with cage. ( 29361854 )
2018
3
Increased PT/SS may play an important role in the pathogenesis of lumbar spondylolisthesis with degenerative lumbar scoliosis. ( 29358108 )
2018
4
A comparison of the techniques of direct pars interarticularis repairs for spondylolysis and low-grade spondylolisthesis: a meta-analysis. ( 29290131 )
2018
5
Posterolateral fusion (PLF) vs. transforaminal lumbar interbody fusion (TLIF) for spondylolisthesis: a systematic review and meta-analysis. ( 29452283 )
2018
6
Decompression with or without concomitant fusion in lumbar stenosis due to degenerative spondylolisthesis: a systematic review. ( 29404693 )
2018
7
The importance of proximal femoral angle on sagittal balance and quality of life in children and adolescents with high-grade lumbosacral spondylolisthesis. ( 29445950 )
2018
8
Direction-changeable lumbar cage versus traditional lumbar cage for treating lumbar spondylolisthesis: A retrospective study. ( 29443791 )
2018
9
Assessment of radiographic and clinical outcomes of an articulating expandable interbody cage in minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis. ( 29290133 )
2018
10
L5 incidence: an important parameter for spinopelvic balance evaluation in high grade spondylolisthesis. ( 29360579 )
2018
11
Does adding interbody fusion to posterolateral fusion increase success in the surgical management of degenerative lumbar spondylolisthesis? ( 29385121 )
2018
12
A novel noninstrumented surgical approach for foramen reconstruction for isthmic spondylolisthesis in patients with radiculopathy: preliminary clinical and radiographic outcomes. ( 29290136 )
2018
13
Utility of Supine Lateral Radiographs for Assessment of Lumbar Segmental Instability in Degenerative Lumbar Spondylolisthesis. ( 29432395 )
2018
14
Minimally invasive anterior and lateral transpsoas approaches for closed reduction of grade II spondylolisthesis: initial clinical and radiographic experience. ( 29290134 )
2018
15
Radiological and functional outcomes of high-grade spondylolisthesis treated by intrasacral fixation, dome resection and circumferential fusion: a retrospective series of 20 consecutive cases with a minimum of 2A years follow-up. ( 29353326 )
2018
16
Minimally invasive transforaminal lumbar interbody fusion using bone cement-augmented pedicle screws for lumbar spondylolisthesis in patients with osteoporosis. Case series and review of literature. ( 29322970 )
2018
17
Current Evidence Regarding the Diagnostic Methods for Pediatric Lumbar Spondylolisthesis: A Report From the Scoliosis Research Society Evidence Based Medicine Committee. ( 29413742 )
2018
18
Achieving Optimal Outcome for Degenerative Lumbar Spondylolisthesis: Randomized Controlled Trial Results. ( 28899038 )
2017
19
A new classification system for degenerative spondylolisthesis of the lumbar spine. ( 28836019 )
2017
20
Current Evidence Regarding the Treatment of Pediatric Lumbar Spondylolisthesis: A Report From the Scoliosis Research Society Evidence Based Medicine Committee. ( 28882346 )
2017
21
Lumbar Spondylolysis And Spondylolisthesis ( 28846329 )
2017
22
Resolution of the more anteriorly positioned psoas muscle following correction of spinal sagittal alignment from spondylolisthesis: case report. ( 28059685 )
2017
23
Vertebral Artery Caught in the Fracture Gap after Traumatic C2/3 Spondylolisthesis. ( 28835861 )
2017
24
Effectiveness of postoperative home-exercise compared with usual care on kinesiophobia and physical activity in spondylolisthesis: A randomized controlled trial. ( 28862315 )
2017
25
Comparing minimally invasive transforaminal lumbar interbody fusion and posterior lumbar interbody fusion for spondylolisthesis: A STROBE-compliant observational study. ( 28906383 )
2017
26
Minimally invasive percutaneous approach for the management of high grade spondylolisthesis. ( 28869369 )
2017
27
Is Stand-Alone Anterior Lumbar Interbody Fusion a Safe and Efficacious Treatment for Isthmic Spondylolisthesis of L5-S1? ( 28894689 )
2017
28
Circumferential Fusion: A Comparative Analysis Between Anterior Lumbar Interbody Fusion with Posterior Pedicle Screw Fixation and Transforaminal Lumbar Interbody Fusion for L5-S1 Isthmic Spondylolisthesis. ( 28821444 )
2017
29
Surgical outcomes in the elderly with degenerative spondylolisthesis, comparative study between patients over 80 years of age and under 80 years-a gender-, diagnosis-, and surgical method-matched two-cohort analyses. ( 28870840 )
2017
30
Risk Factors Of Postoperative Low Back Pain For Low Grade Degenerative Spondylolisthesis: An At Least 2-year Follow-up Retrospective Study. ( 28844918 )
2017
31
Thoracic spondylolisthesis and spinal cord compression in diffuse idiopathic skeletal hyperostosis: a case report. ( 28363281 )
2017
32
Variation of facet joint orientation and tropism in lumbar degenerative spondylolisthesis and disc herniation at L4-L5: A systematic review and meta-analysis. ( 28843706 )
2017
33
Responsiveness of the bridge maneuvers in subjects with symptomatic lumbar spondylolisthesis: A prospective cohort study. ( 28060461 )
2017
34
Segmental polymethylmethacrylate-augmented fenestrated pedicle screw fixation for lumbar spondylolisthesis in patients with osteoporosis - A case series and review of literature. ( 28084247 )
2017
35
An increase in the degree of olisthesis during axial loading reduces the dural sac size and worsens clinical symptoms in patients with degenerative spondylolisthesis. ( 28870841 )
2017
36
Postoperative Evaluation of Health-Related Quality-of-Life (HRQoL) of Patients With Lumbar Degenerative Spondylolisthesis After Instrumented Posterolateral Fusion (PLF): A prospective Study With a 2-Year Follow-Up. ( 29387287 )
2017
37
Correction of Grade 2 Spondylolisthesis Following a Non-Surgical Structural Spinal Rehabilitation Protocol Using Lumbar Traction: A Case Study and Selective Review of Literature. ( 29299090 )
2017
38
Congenital hypoplasia of the lumbar pedicle with spondylolisthesis: report of 2 cases. ( 28059687 )
2017
39
A case of brucellar spondylitis with lumbar spondylolisthesis. ( 29340473 )
2017
40
High-grade spondylolytic spondylolisthesis. ( 28928499 )
2017
41
Posterolateral Fusion Versus Interbody Fusion for Degenerative Spondylolisthesis: Systematic Review and Meta-Analysis. ( 28811993 )
2017
42
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial. ( 28072709 )
2017
43
Degenerative spondylolisthesis: contemporary review of the role of interbody fusion. ( 27888353 )
2017
44
Radiographic Risk Factors of Reoperation Following Minimally Invasive Decompression for Lumbar Canal Stenosis Associated With Degenerative Scoliosis and Spondylolisthesis. ( 28894678 )
2017
45
Quality of Life and Slip Progression in Degenerative Spondylolisthesis Treated Non-Operatively. ( 28953710 )
2017
46
Double-level isthmic spondylolisthesis treated with posterior lumbar interbody fusion: A review of 32 cases. ( 28843115 )
2017
47
Spondylolisthesis with spondylolysis in a 17-month-old: a case report. ( 29354748 )
2017
48
Lumbar Degenerative Spondylolisthesis: Changes in Surgical Indications and Comparison of Instrumented Fusion with Two Surgical Decompression Procedures: Erratum. ( 28800573 )
2017
49
Guideline summary review: an evidence-based clinical guideline for the diagnosis and treatment of adult isthmic spondylolisthesis. ( 27592807 )
2016
50
Surgical Versus Nonsurgical Treatment for High-Grade Spondylolisthesis in Children and Adolescents: A Systematic Review and Meta-Analysis. ( 26986134 )
2016

Variations for Spondylolisthesis

Expression for Spondylolisthesis

Search GEO for disease gene expression data for Spondylolisthesis.

Pathways for Spondylolisthesis

GO Terms for Spondylolisthesis

Biological processes related to Spondylolisthesis according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.9 BMP2 FTH1 IVD PTGS2
2 negative regulation of cell proliferation GO:0008285 9.8 BMP2 BMP7 FTH1 PTGS2
3 response to estradiol GO:0032355 9.65 BMP7 ESR1 PTGS2
4 positive regulation of neuron differentiation GO:0045666 9.61 BMP2 BMP7 GDF5
5 positive regulation of cell death GO:0010942 9.59 BMP7 PTGS2
6 positive regulation of cell differentiation GO:0045597 9.58 BMP2 BMP7
7 positive regulation of epithelial to mesenchymal transition GO:0010718 9.58 BMP2 BMP7
8 cartilage development GO:0051216 9.58 BMP2 BMP7 GDF5
9 chondrocyte differentiation GO:0002062 9.57 BMP2 GDF5
10 epithelial to mesenchymal transition GO:0001837 9.56 BMP2 BMP7
11 cellular response to BMP stimulus GO:0071773 9.55 BMP2 BMP7
12 bone mineralization GO:0030282 9.54 BMP2 PTGS2
13 positive regulation of bone mineralization GO:0030501 9.52 BMP2 BMP7
14 response to vitamin D GO:0033280 9.51 BMP7 PTGS2
15 SMAD protein signal transduction GO:0060395 9.5 BMP2 BMP7 GDF5
16 mesenchymal cell differentiation GO:0048762 9.46 BMP2 BMP7
17 regulation of branching involved in prostate gland morphogenesis GO:0060687 9.37 BMP7 ESR1
18 cell development GO:0048468 9.33 BMP2 BMP7 GDF5
19 mesenchyme development GO:0060485 9.26 BMP2 BMP7
20 positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 9.13 BMP2 BMP7 GDF5
21 negative regulation of cell cycle GO:0045786 8.8 BMP2 BMP7 PTGS2

Molecular functions related to Spondylolisthesis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 BMP2 BMP7 GDF5
2 growth factor activity GO:0008083 9.33 BMP2 BMP7 GDF5
3 BMP receptor binding GO:0070700 8.96 BMP2 BMP7
4 transforming growth factor beta receptor binding GO:0005160 8.8 BMP2 BMP7 GDF5

Sources for Spondylolisthesis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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