MCID: SPN029
MIFTS: 30

Spondylolysis malady

Summaries for Spondylolysis

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Wikipedia:63 Spondylolysis is a defect of a vertebra. More specifically it is defined as a defect in the pars... more...

MalaCards: Spondylolysis is related to spondylolisthesis and cervicitis. An important gene associated with Spondylolysis is BMP7 (bone morphogenetic protein 7). The drug baclofen has been mentioned in the context of this disorder. Affiliated tissues include lumbar vertebral column, bone and testes.

Disease Ontology:8 A bone structure disease that involves a defect located in lumbar vertebral column.

Aliases & Classifications for Spondylolysis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Classifications:



Aliases & Descriptions:

spondylolysis 8 10 44 60


External Ids:

Disease Ontology8 DOID:2300
NCIt39 C35034
MeSH34 D013169
ICD1025 M43.0

Related Diseases for Spondylolysis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Spondylolysis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 20)
idRelated DiseaseScoreTop Affiliating Genes
1spondylolisthesis31.4PGRMC1, BMP7
2cervicitis10.7
3radiculopathy10.2
4osteopetrosis10.2
5osteogenesis imperfecta10.2
6syringomyelia10.1
7acute cervicitis10.1
8chronic cervicitis10.1
9spina bifida10.1
10discitis9.9
11ankylosing spondylitis9.9
12epidural abscess9.9
13cerebritis9.9
14spondylosis9.9
15scheuermann's disease9.9
16pycnodysostosis9.9
17aortic aneurysm9.9
18cerebral palsy9.9
19ruptured aortic aneurysm9.9
20spondylitis9.9

Graphical network of diseases related to Spondylolysis:



Diseases related to spondylolysis

Clinical Features for Spondylolysis

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Drugs & Therapeutics for Spondylolysis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Spondylolysis

Drug clinical trials:

Search ClinicalTrials for Spondylolysis

Search NIH Clinical Center for Spondylolysis

Search CenterWatch for Spondylolysis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Spondylolysis

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Anatomical Context for Spondylolysis

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Spondylolysis:

32
Bone, Testes

FMA organs/tissues related to Spondylolysis:

14
Lumbar vertebral column

Animal Models for Spondylolysis or affiliated genes

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Publications for Spondylolysis

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Sources:
50PubMed
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Articles related to Spondylolysis:

(show top 50)    (show all 467)
idTitleAuthorsYear
1
Lumbar spondylolysis in juveniles from the same family: a report of three cases and a review of the literature. (24191211)
2013
2
A universal pedicle screw and V-rod system for lumbar isthmic spondylolysis: a retrospective analysis of 21 cases. (23691090)
2013
3
Spondylolysis of C-2 in children 3 years of age or younger: clinical presentation, radiographic findings, management, and outcomes with a minimum 12-month follow-up. (24359209)
2013
4
Bilateral three-level lumbar spondylolysis repaired by hook-screw technique. (24353947)
2012
5
Return to sports activity by athletes after treatment of spondylolysis. (22474624)
2010
6
Spondylolysis: a review and reappraisal. (20411054)
2010
7
Direct repair of spondylolysis by TSRH's hook plus screw fixation and bone grafting: biomechanical study and clinical report. (19440723)
2010
8
Lumbar spine spondylolysis in the adult population: using computed tomography to evaluate the possibility of adult onset lumbar spondylosis as a cause of back pain. (19911181)
2010
9
Chiropractic management of mechanical low back pain secondary to multiple-level lumbar spondylolysis with spondylolisthesis in a United States Marine Corps veteran: a case report. (19703668)
2009
10
Radiographic assessment of lumbar facet distance spacing and pediatric spondylolysis. (19179924)
2009
11
Segmental wire fixation for lumbar spondylolysis associated with spina bifida occulta. (18040701)
2008
12
Radiographic assessment of lumbar facet distance spacing and spondylolysis. (17224804)
2007
13
Assessment of bony union following surgical stabilisation for lumbar spondylolysis: a comparative study between radiography and computed tomography. (16598081)
2006
14
Magnetic resonance imaging in diagnosis and follow-up of impending spondylolysis in children and adolescents: early treatment may prevent pars defects. (15703512)
2005
15
Biomechanical rationale of endoscopic decompression for lumbar spondylolysis as an effective minimally invasive procedure - a study based on the finite element analysis. (15906208)
2005
16
Spondylolysis and spondylolisthesis in the child and adolescent: a new classification. (15864031)
2005
17
Lumbar spondylolysis in pediatric and adolescent soccer players. (16093537)
2005
18
Comparing spondylolysis in cricketers and soccer players. (15562169)
2004
19
Spondylolysis: returning the athlete to sports participation with brace treatment. (12083575)
2002
20
Distinguishing scintigraphic features of spondylolysis. (11961444)
2002
21
Spondylolysis in active adolescents: expediting return to play. (20086560)
2001
22
Nonoperative treatment of active spondylolysis in elite athletes with normal X-ray findings: literature review and results of conservative treatment. (11806390)
2001
23
Management of multiple level spondylolysis of the lumbar spine in young males: a report of six cases. (11579618)
2001
24
Slippage mechanism of pediatric spondylolysis: biomechanical study using immature calf spines. (11598509)
2001
25
The radiological investigation of lumbar spondylolysis. (9817088)
1998
26
Spondylolysis of the sacrum in Alaskan and Canadian Inuit skeletons. (8922182)
1996
27
Lumbar spondylolysis in children and adolescents. (7615609)
1995
28
A study of the efficacy of nonoperative treatment of presumed traumatic spondylolysis in a young patient population. (8538888)
1995
29
Case report 868. Congenital bilateral spondylolysis and spondylolisthesis of the fourth cervical vertebra. (7824992)
1994
30
Spondylolysis after posterior decompression of the lumbar spine. 35 patients followed for 3-9 years. (8451937)
1993
31
Spondylolysis in fast bowlers: principles of prevention and a survey of awareness among cricket coaches. (1490223)
1992
32
Treatment of spondylolysis and spondylolisthesis with Cotrel-Dubousset instrumentation: a preliminary report. (1839776)
1991
33
CT of bilateral cervical spondylolysis. (1898562)
1991
34
Congenital fusion C0-C2 associated with spondylolysis of C2. (2134459)
1990
35
Post-traumatic spinal synovial cyst with spondylolysis: CT features. (2925925)
1989
36
Occupational spondylolysis and spondylolisthesis. (2661033)
1989
37
Spondylolysis and spondylolisthesis in young athletes: 28 cases. (3294508)
1988
38
Spondylolysis and spondylolisthesis. Treatment by internal fixation and bone-grafting of the defect. (3275672)
1988
39
Acquired spondylolysis after posterolateral spinal fusion. (3558808)
1987
40
Lumbar spondylolysis and spondylolisthesis in college football players. A prospective study. (3777317)
1986
41
Significance of bone scintigraphy in symptomatic spondylolysis. (6238425)
1984
42
Spondylolysis of C2: CT and plain film findings. (6841719)
1983
43
Double-level spondylolysis and transitional vertebra. Case report. (1150723)
1975
44
Acquired spondylolysis and spondylolisthesis. Case report. (4727694)
1973
45
Spondylolysis and spondylolisthesis in children: a review. (4252416)
1971
46
Spondylolysis in the Alaskan Eskimo. (5580015)
1971
47
Further evidence on the acquired nature of spondylolysis and spondylolisthesis. (5437284)
1970
48
RESULTS OF ANTERIOR SPINE FUSION BY EXTRAPERITONEAL APPROACH FOR SPONDYLOLYSIS AND SPONDYLOLISTHESIS. (14162121)
1963
49
Spondylolysis; its anatomy and mechanism of development. (13630966)
1959
50
Spondylolysis and spondylolisthesis. (21066051)
1946

Genetic Variations for Spondylolysis

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Expression for genes affiliated with Spondylolysis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Spondylolysis

Search GEO for disease gene expression data for Spondylolysis.

Pathways for genes affiliated with Spondylolysis

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Compounds for genes affiliated with Spondylolysis

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GO Terms for genes affiliated with Spondylolysis

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Products for genes affiliated with Spondylolysis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Spondylolysis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet