MCID: SPN029
MIFTS: 29

Spondylolysis malady

Summaries for Spondylolysis

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Spondylolysis is a defect of a vertebra. More specifically it is defined as a defect in the pars... more...

MalaCards: Spondylolysis is related to spondylolisthesis and back pain. An important gene associated with Spondylolysis is BMP7 (bone morphogenetic protein 7). The drug baclofen has been mentioned in the context of this disorder. Affiliated tissues include lumbar vertebral column and bone marrow.

Disease Ontology:8 A bone structure disease that involves a defect located in lumbar vertebral column.

Aliases & Classifications for Spondylolysis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 40NCIt, 35MeSH, 25ICD10
See all sources

Classifications:



Aliases & Descriptions:

spondylolysis 8 10 45 61


External Ids:

Disease Ontology8 DOID:2300
NCIt40 C35034
MeSH35 D013169
ICD1025 M43.0

Related Diseases for Spondylolysis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Spondylolysis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 20)
idRelated DiseaseScoreTop Affiliating Genes
1spondylolisthesis31.5PGRMC1, BMP7
2back pain10.5
3radiculopathy10.2
4osteopetrosis10.2
5osteogenesis imperfecta10.2
6syringomyelia10.1
7spina bifida10.1
8spina bifida occulta10.1
9chronic pain10.1
10discitis9.9
11ankylosing spondylitis9.9
12epidural abscess9.9
13spondylosis9.9
14scheuermann's disease9.9
15pycnodysostosis9.9
16arc syndrome9.9
17aortic aneurysm9.9
18spondylitis9.9
19idiopathic adolescent scoliosis9.9
20lumbar disc herniation9.9

Graphical network of diseases related to Spondylolysis:



Diseases related to spondylolysis

Clinical Features for Spondylolysis

Drugs & Therapeutics for Spondylolysis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Spondylolysis

Drug clinical trials:

Search ClinicalTrials for Spondylolysis

Search NIH Clinical Center for Spondylolysis

Search CenterWatch for Spondylolysis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Spondylolysis

Anatomical Context for Spondylolysis

Sources:
14FMA, 33MalaCards
See all sources

MalaCards organs/tissues related to Spondylolysis:

33
Bone marrow

FMA organs/tissues related to Spondylolysis:

14
Lumbar vertebral column

Animal Models for Spondylolysis or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Spondylolysis

Sources:
51PubMed
See all sources

Articles related to Spondylolysis:

(show top 50)    (show all 467)
idTitleAuthorsYear
1
Congenital absence of the lumbar facet joint associated with bilateral spondylolysis of the fifth lumbar vertebra. (23438665)
2013
2
Infectious or noninfectious? Ruptured, thrombosed inflammatory aortic aneurysm with spondylolysis. (22972586)
2013
3
Diagnosis of radiographically occult lumbar spondylolysis in young athletes by magnetic resonance imaging. (23136176)
2013
4
Bilateral spondylolysis of inferior articular processes of the fourth lumbar vertebra: a case report. (22111522)
2012
5
Spondylolysis is frequently missed by MRI in adolescents with back pain. (23814624)
2012
6
Evaluation of the relationship between L5-S1 spondylolysis and isthmic spondylolisthesis and lumbosacral-pelvic morphology by imaging via 2- and 3-dimensional reformatted computed tomography. (21150453)
2011
7
Apophysitis of the posterior superior iliac spine associated with lumbar spondylolysis in a high school athlete. (21497326)
2011
8
Conservative treatment of lumbar spondylolysis in young soccer players. (21541713)
2011
9
Spondylolysis of C-2 in 2 athletically active individuals. (20594012)
2010
10
Resolution of an intraspinal cyst associated with spondylolysis causing radiculopathy in an adolescent athlete: a case report. (21093843)
2010
11
Direct screw fixation of the spondylolysis without fusion. (20960657)
2010
12
Bilateral pedicle stress fracture accompanying spondylolysis in a patient with ankylosing spondylitis. (20717516)
2010
13
Multiple levels of lumbar spondylolysis - a case report -. (20404945)
2009
14
Prevalence of vertebral pars defects (spondylolysis) in a population with osteogenesis imperfecta. (19478660)
2009
15
Symptom assessment in lumbar stenosis/spondylolysis - patient questionnaire versus physician chart. (19918700)
2009
16
Conservative treatment of lumbar spondylolysis in childhood and adolescence: the radiological signs which predict healing. (19190055)
2009
17
Surgical management of spondylolysis and spondylolisthesis in athletes: indications and return to play. (19142078)
2009
18
Posterior arch defects of the cervical spine: a comparison between absent pedicle syndrome and spondylolysis. (19233739)
2009
19
Spondylolisthesis and spondylolysis. (18399601)
2008
20
Biomechanical and clinical evaluation of a novel technique for surgical repair of spondylolysis in adolescents. (16915090)
2006
21
Spondylolysis and spondylolisthesis in children and adolescents: II. Surgical management. (16885480)
2006
22
Scoliosis research society outcome instrument in evaluation of long-term surgical results in spondylolysis and low-grade isthmic spondylolisthesis in young patients. (15682016)
2005
23
Traumatic spondylolysis in a heptathlete: a case history and review. (19674651)
2005
24
Spondylolysis and spondylolisthesis in the athlete. (16295191)
2005
25
Computed tomorgaphy diagnostic of lumbar spondylolysis. (17618216)
2004
26
Returning athletes with severe low back pain and spondylolysis to original sporting activities with conservative treatment. (15546329)
2004
27
The value of combining single photon emission computerised tomography and computerised tomography in the investigation of spondylolysis. (15118897)
2004
28
The biomechanical effects of spondylolysis and its treatment. (12567023)
2003
29
Biomechanical functions of the iliolumbar ligament in L5 spondylolysis. (10982664)
2000
30
Spondylolysis of the axis vertebra: a rare anomaly simulating hangman's fracture. (9930829)
1999
31
Isolated fracture of the vertebral articular facet in a gymnast. A spondylolysis mimic. (9934428)
1999
32
Spondyloptosis and multiple-level spondylolysis. (10190858)
1999
33
Suspecting lumbar spondylolysis in adolescent low back pain. (9597294)
1998
34
Spondylolysis. An historical review. (8560348)
1995
35
Incomplete spondylolysis and healing. A study of ancient Canadian Eskimo skeletons. (8553121)
1995
36
Cervical spondylolysis: imaging findings in 12 patients. (2107670)
1990
37
Lumbar spondylolysis: occurrence in competitive athletes. Updated achievements in a series of 390 cases. (2079853)
1990
38
Tension band wiring-bone grafting for spondylolysis and spondylolisthesis. A clinical and biomechanical study. (2655114)
1989
39
Spondylolysis of the axis. A case report and review of the literature. (2695521)
1989
40
Degenerative spondylolisthesis with unilateral spondylolysis. A case report. (3410617)
1988
41
Unilateral spondylolysis and contralateral pedicle fracture. (3704787)
1986
42
"Incomplete ring" sign: a simple method for CT detection of spondylolysis. (4019830)
1985
43
Spondylolysis of the lumbar spine: demonstration of defects and laminal fragmentation. (6494460)
1984
44
Relationship between radiological and clinical variables in spondylolysis. (6241610)
1984
45
Upper lumbar spondylolysis. (7275406)
1981
46
Strain on the interarticular stress distribution. Measurements regarding the development of spondylolysis. (7425808)
1980
47
Variations in the amount and distribution of cortical bone across the partes interarticulares of L5. A predisposing factor in spondylolysis? (264031)
1979
48
Reactive sclerosis of a pedicle and spondylolysis in the lumbar spine. (833174)
1977
49
Mechanical factors in spondylolisthesis and spondylolysis. (1277687)
1976
50
Interarticular isthmus hiatus (spondylolysis). (20987893)
1946

Genetic Variations for Spondylolysis

Expression for genes affiliated with Spondylolysis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Spondylolysis

Search GEO for disease gene expression data for Spondylolysis.

Pathways for genes affiliated with Spondylolysis

Compounds for genes affiliated with Spondylolysis

GO Terms for genes affiliated with Spondylolysis

Products for genes affiliated with Spondylolysis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Spondylolysis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet