MCID: SPN029
MIFTS: 30

Spondylolysis malady

Summaries for Spondylolysis

About this section
Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Spondylolysis is a defect of a vertebra. More specifically it is defined as a defect in the pars... more...

MalaCards: Spondylolysis is related to spondylolisthesis and cervicitis. An important gene associated with Spondylolysis is BMP7 (bone morphogenetic protein 7). The drug baclofen has been mentioned in the context of this disorder. Affiliated tissues include lumbar vertebral column, bone and testes.

Disease Ontology:8 A bone structure disease that involves a defect located in lumbar vertebral column.

Aliases & Classifications for Spondylolysis

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
See all sources

Classifications:



Aliases & Descriptions:

spondylolysis 8 10 44 60


External Ids:

Disease Ontology8 DOID:2300
NCIt39 C35034
MeSH34 D013169
ICD1025 M43.0

Related Diseases for Spondylolysis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Spondylolysis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 20)
idRelated DiseaseScoreTop Affiliating Genes
1spondylolisthesis31.4PGRMC1, BMP7
2cervicitis10.7
3radiculopathy10.2
4osteopetrosis10.2
5osteogenesis imperfecta10.2
6syringomyelia10.1
7acute cervicitis10.1
8chronic cervicitis10.1
9spina bifida10.1
10discitis9.9
11ankylosing spondylitis9.9
12epidural abscess9.9
13cerebritis9.9
14spondylosis9.9
15scheuermann's disease9.9
16pycnodysostosis9.9
17aortic aneurysm9.9
18cerebral palsy9.9
19ruptured aortic aneurysm9.9
20spondylitis9.9

Graphical network of diseases related to Spondylolysis:



Diseases related to spondylolysis

Clinical Features for Spondylolysis

About this section

Drugs & Therapeutics for Spondylolysis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Spondylolysis

Drug clinical trials:

Search ClinicalTrials for Spondylolysis

Search NIH Clinical Center for Spondylolysis

Search CenterWatch for Spondylolysis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Spondylolysis

About this section

Anatomical Context for Spondylolysis

About this section
Sources:
32MalaCards, 14FMA
See all sources

MalaCards organs/tissues related to Spondylolysis:

32
Bone, Testes

FMA organs/tissues related to Spondylolysis:

14
Lumbar vertebral column

Animal Models for Spondylolysis or affiliated genes

About this section

Publications for Spondylolysis

About this section
Sources:
50PubMed
See all sources

Articles related to Spondylolysis:

(show top 50)    (show all 467)
idTitleAuthorsYear
1
Surgically Treated Cases of Lumbar Spondylolysis and Isthmic Spondylolisthesis: A Multicenter Study. (23222096)
2013
2
Pediatric cervical spondylolysis and American football. (24345471)
2013
3
Re: Niggemann P, Kuchta J, Beyer HK, et al. Spondylolysis and spondylolisthesis: prevalence of different forms of instability and clinical implications. Spine 2011;36:E1463a898. (22310099)
2012
4
Lumbar shape characterization of the neural arch and vertebral body in spondylolysis: A comparative skeletal study. (21647967)
2012
5
Lumbar spondylolysis: a review. (20440613)
2011
6
The incidence of spondylolysis and spondylolisthesis in children with osteogenesis imperfecta. (21841441)
2011
7
Spinal nerve root herniation into a pseudomeningocele associated with lumbar spondylolysis: a case report. (21187554)
2010
8
Facet orientation and tropism: associations with spondylolysis. (20072037)
2010
9
Causes of radiculopathy in young athletes with spondylolysis. (19959743)
2010
10
Hypoplasia of L5 and wedging and pseudospondylolisthesis in patients with spondylolysis: study with MR imaging. (19147712)
2009
11
Spondylolysis and spondylolisthesis: prevalence and association with low back pain in the adult community-based population. (19139672)
2009
12
Cervical spondylolysis in a judo player: a case report and biomechanical analysis. (18437403)
2009
13
Spondylolysis and spondylolisthesis in the athlete. (18277260)
2008
14
Spondylolysis of the second lumbar vertebra treated with segmental wiring and bone grafting. (19292222)
2008
15
Direct repair for treatment of symptomatic spondylolysis and low-grade isthmic spondylolisthesis in young patients: no benefit in comparison to segmental fusion after a mean follow-up of 14.8 years. (16463195)
2006
16
Finite element analysis of the spondylolysis in lumbar spine. (17075165)
2006
17
MRI signal changes of the pedicle as an indicator for early diagnosis of spondylolysis in children and adolescents: a clinical and biomechanical study. (16418642)
2006
18
Correlation between pre-employment screening X-ray finding of spondylolysis and sickness absenteeism due to low back pain among policemen of the Israeli police force. (15454711)
2004
19
Spondylolysis and spondylolisthesis in the child and adolescent athlete. (12974495)
2003
20
A new endoscopic technique to decompress lumbar nerve roots affected by spondylolysis. Technical note. (12691388)
2003
21
Spondylolysis: a critical review. (11131228)
2000
22
A physiological method for the repair of young adult simple isthmic lumbar spondylolysis. (10835804)
2000
23
Spondylolysis as a cause of low back pain in swimmers. (10950449)
2000
24
Spondylolysis at three sites in the same lumbar vertebra. (10090464)
1999
25
Radiology rounds. Bilateral spondylolysis at L5 with associated spondylolisthesis. (10386209)
1999
26
MR imaging of fibrocartilaginous masses arising on the margins of spondylolysis defects. (10470901)
1999
27
A biomechanic study of the surgical repair technique of pars defect in spondylolysis. (9803080)
1998
28
Treatment of spondylolysis with external electrical stimulation and bracing in adolescent athletes: a report of two cases. (9762484)
1998
29
The role of transitional vertebrae in spondylolysis and spondylolytic spondylolisthesis. (9361917)
1997
30
Vertebral slip in lumbar spondylolysis and spondylolisthesis. Long-term follow-up of 22 adult patients. (7559708)
1995
31
SPECT evaluation of lumbar spondylolysis and spondylolisthesis. (8184357)
1994
32
Direct repair of lumbar spondylolysis. 10-year follow-up of 12 previously reported cases. (8154293)
1994
33
Spondylolysis. Bending of the inferior articular processes of lumbar vertebrae during simulated spinal movements. (7899964)
1994
34
Acute spondylolysis in an adolescent. (7854824)
1994
35
Repair of lumbar spondylolysis with a hook-screw. (1572778)
1992
36
Translamino-pedicular screw fixation with bone grafting for symptomatic isthmic lumbar spondylolysis. (1620301)
1992
37
Cervical spondylolysis. (2308885)
1990
38
Bone scintigraphy in the assessment of spondylolysis in patients attending a sports injury clinic. (3396276)
1988
39
Scoliosis in young men with spondylolysis or spondylolisthesis. A comparative study in symptomatic and asymptomatic subjects. (6495008)
1984
40
Upper lumbar spondylolysis: report of two cases. (6438551)
1984
41
Management of spondylolysis and spondylolisthesis. (6546063)
1983
42
Spondylolysis studied with computed tomography. (7146406)
1982
43
Scoliosis and spondylolysis-spondylolisthesis. (7316698)
1981
44
Familial occurrence of lumbar spondylolysis and spondylolisthesis. (668183)
1978
45
Cervical spondylolysis with spondylolisthesis. Case report. (1194942)
1975
46
Spondylolysis following trauma: a case report. (5687797)
1968
47
Studies of familial incidence of spondylolysis. (5587812)
1967
48
Spondylolysis following spinal fusion. Report of a case. (13815984)
1959
49
Spondyloysis and spondylolisthesis; case report clarifying the etiology of spondylolysis. (13494717)
1957
50
Fatigue fracture of the fifth lumbar neural arch; is spondylolysis a stress fracture? (13270427)
1955

Genetic Variations for Spondylolysis

About this section

Expression for genes affiliated with Spondylolysis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Spondylolysis

Search GEO for disease gene expression data for Spondylolysis.

Pathways for genes affiliated with Spondylolysis

About this section

Compounds for genes affiliated with Spondylolysis

About this section

GO Terms for genes affiliated with Spondylolysis

About this section

Products for genes affiliated with Spondylolysis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Spondylolysis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet