MCID: SPN020
MIFTS: 52

Spondylosis

Categories: Neuronal diseases, Bone diseases

Aliases & Classifications for Spondylosis

MalaCards integrated aliases for Spondylosis:

Name: Spondylosis 12 41 14 69
Spondylogenic Compression of Thoracic Spinal Cord 12
Spondylogenic Compression of Lumbar Spinal Cord 12
Thoracic or Lumbar Spondylosis with Myelopathy 12
Lumbosacral Spondylosis Without Myelopathy 12
Lumbar Spondylosis with Myelopathy 12
Spondylosis with Myelopathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2247
ICD10 32 M47 M47.9
ICD9CM 34 721.9
MeSH 41 D055009
UMLS 69 C0038019

Summaries for Spondylosis

Disease Ontology : 12 An bone structure disease that involves degeneration between vertebra located in vertebral column.

MalaCards based summary : Spondylosis, also known as spondylogenic compression of thoracic spinal cord, is related to head injury and osteoporosis. An important gene associated with Spondylosis is HTRA1 (HtrA Serine Peptidase 1), and among its related pathways/superpathways are Development_Hedgehog and PTH signaling pathways in bone and cartilage development and Endocrine and other factor-regulated calcium reabsorption. The drugs Dexamethasone and Pregabalin have been mentioned in the context of this disorder. Affiliated tissues include vertebral column, spinal cord and bone, and related phenotypes are growth/size/body region and cardiovascular system

Wikipedia : 72 Spondylosis is a broad term meaning degeneration of the spinal column from any cause. In the more narrow... more...

Related Diseases for Spondylosis

Diseases related to Spondylosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 136)
# Related Disease Score Top Affiliating Genes
1 head injury 30.1 ENO2 S100B
2 osteoporosis 27.2 ESR1 HMGCR IL1B KL PTH VDR
3 spondylosis, cervical 12.1
4 central cord syndrome 11.2
5 cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 11.1
6 cervicitis 11.0
7 spinal cord disease 10.9
8 spastic paraplegia 25 10.9
9 intracranial cysts 10.5 ENO2 S100B
10 bednar tumor 10.5 ENO2 S100B
11 epithelioid malignant peripheral nerve sheath tumor 10.5 ENO2 S100B
12 middle cerebral artery infarction 10.5 ENO2 S100B
13 ossifying fibromyxoid tumor 10.5 ENO2 S100B
14 pineocytoma 10.4 ENO2 S100B
15 papillary ependymoma 10.4 ENO2 S100B
16 subependymal giant cell astrocytoma 10.4 ENO2 S100B
17 granular cell tumor 10.4 ENO2 S100B
18 meningeal melanocytoma 10.4 ENO2 S100B
19 olfactory neuroblastoma 10.4 ENO2 S100B
20 cerebral primitive neuroectodermal tumor 10.4 ENO2 S100B
21 traumatic brain injury 10.4 ENO2 S100B
22 pilomatrixoma 10.4 ENO2 S100B
23 optic nerve glioma 10.4 ENO2 S100B
24 campylobacteriosis 10.3 IL1B VDR
25 clear cell adenoma 10.3 PTH S100B
26 acute mountain sickness 10.3 ENO2 S100B
27 episodic pain syndrome, familial, 1 10.3
28 extraosseous ewing's sarcoma 10.3 ENO2 S100B
29 ganglioglioma 10.3 ENO2 S100B
30 cloacogenic carcinoma 10.3 ENO2 PTH
31 cervical clear cell adenocarcinoma 10.3 ENO2 ESR1
32 syringoma 10.3 ESR1 S100B
33 vulvar vestibulitis syndrome 10.3 ESR1 IL1B
34 mixed cell type cancer 10.3 ENO2 ESR1
35 calciphylaxis 10.3 PTH VDR
36 brain injury 10.3 ENO2 S100B
37 hypercalcemia, infantile, 1 10.3 PTH VDR
38 idiopathic hypercalciuria 10.2 IL1B VDR
39 vaginitis 10.2 ESR1 IL1B
40 endometrial disease 10.2 ESR1 IL1B
41 protrusio acetabuli 10.2 ESR1 VDR
42 rapadilino syndrome 10.2 HELLS WRN
43 hidradenocarcinoma 10.2 ESR1 S100B
44 desmoplastic small round cell tumor 10.2 ENO2 S100B
45 endometritis 10.2 ESR1 IL1B
46 secondary hyperparathyroidism of renal origin 10.2 PTH VDR
47 parathyroid gland disease 10.2 PTH VDR
48 secondary progressive multiple sclerosis 10.2 ENO2 S100B
49 mevalonic aciduria 10.2 HMGCR IL1B
50 renal osteodystrophy 10.2 PTH VDR

Comorbidity relations with Spondylosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Spondylosis:



Diseases related to Spondylosis

Symptoms & Phenotypes for Spondylosis

MGI Mouse Phenotypes related to Spondylosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.07 WRN HMGCR HTRA1 VDR IL1B ENO2
2 cardiovascular system MP:0005385 10 WRN HTRA1 VDR IL1B KL ESR1
3 craniofacial MP:0005382 9.91 WRN VDR IL1B ENO2 KL PTH
4 homeostasis/metabolism MP:0005376 9.91 WRN HMGCR S100B VDR IL1B KL
5 endocrine/exocrine gland MP:0005379 9.88 WRN VDR HELLS PTH KL ESR1
6 hematopoietic system MP:0005397 9.87 WRN PTH VDR IL1B KL ESR1
7 integument MP:0010771 9.7 WRN S100B VDR IL1B KL ESR1
8 limbs/digits/tail MP:0005371 9.43 WRN VDR KL ESR1 PTH HELLS
9 skeleton MP:0005390 9.23 WRN HTRA1 VDR IL1B KL ESR1

Drugs & Therapeutics for Spondylosis

Drugs for Spondylosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
2
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
3
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
4
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
5
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
6
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
7
Menthol Approved Phase 4 2216-51-5 16666
8 Hormones Phase 4,Phase 3
9 BB 1101 Phase 4,Phase 2
10 Dexamethasone acetate Phase 4,Phase 2 1177-87-3
11 Analgesics Phase 4,Phase 2,Phase 3
12 Anti-Anxiety Agents Phase 4
13 Anticonvulsants Phase 4
14 calcium channel blockers Phase 4
15 Calcium, Dietary Phase 4
16 Central Nervous System Depressants Phase 4,Phase 2,Phase 3
17 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
18 Psychotropic Drugs Phase 4
19 Tranquilizing Agents Phase 4
20 Anesthetics Phase 4,Phase 2,Phase 3
21 Anesthetics, Local Phase 4,Phase 2
22 Anti-Arrhythmia Agents Phase 4
23 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
24 Diuretics, Potassium Sparing Phase 4
25 glucocorticoids Phase 4,Phase 3
26 Hormone Antagonists Phase 4,Phase 3
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
28 Immunosuppressive Agents Phase 4
29 Sodium Channel Blockers Phase 4
30 triamcinolone acetonide Phase 4
31 Triamcinolone diacetate Phase 4
32 Triamcinolone hexacetonide Phase 4
33 Analgesics, Opioid Phase 4
34 Anesthetics, Dissociative Phase 4
35 Anesthetics, General Phase 4
36 Anesthetics, Intravenous Phase 4
37 Excitatory Amino Acid Antagonists Phase 4
38 Excitatory Amino Acids Phase 4
39 Narcotics Phase 4,Phase 2
40 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
41 Antiemetics Phase 4,Phase 3
42 Antineoplastic Agents, Hormonal Phase 4,Phase 3
43 Autonomic Agents Phase 4,Phase 3
44 Gastrointestinal Agents Phase 4,Phase 3
45 HIV Protease Inhibitors Phase 4
46
protease inhibitors Phase 4
47
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3 76631-46-4, 113775-47-6 5311068 56032 68602
48
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
49
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
50 Hypnotics and Sedatives Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 171)

# Name Status NCT ID Phase Drugs
1 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
2 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4 Triamcinolone 80mg
3 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
4 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
5 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
6 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
7 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
8 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
9 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
10 Particulate Corticosteroid Versus Non-particulate Corticosteroid for Sacroiliac Joint Injection Enrolling by invitation NCT03166761 Phase 4 Dexamethasone;Triamcinolone Acetonide
11 Efficacy of Using Solum IV and BMC With GFC in TLIF Not yet recruiting NCT03223701 Phase 4
12 Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis Terminated NCT01560273 Phase 4
13 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
14 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
15 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
16 The CSM Trial: A Multicenter Study Comparing Ventral to Dorsal Surgery for Cervical Spondylotic Myelopathy Completed NCT00506558 Phase 3
17 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
18 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
19 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
20 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Recruiting NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
21 Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Not yet recruiting NCT03327272 Phase 3 Methylprednisolone;Saline
22 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
23 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
24 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
25 Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain Completed NCT00587626 Phase 2
26 Effect of Cervical Collar in Cervical Radicular Pain. Completed NCT00395798 Phase 2
27 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
29 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
30 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
31 Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery Recruiting NCT02276911 Phase 2 Ibuprofen
32 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
33 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
34 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
35 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
36 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
37 The CX-DZ-Ⅱ Intelligent Electroacupuncture Instrument for Neck Pain Not yet recruiting NCT03005301 Phase 1
38 Study on the Early Warning and Treatment of Cervical Spondylosis of Cervical Type on Young People Based on the " Move Generate Yang " Theory Unknown status NCT02199405
39 Baxter: Actifuse SHAPE vs DBX in ACC Unknown status NCT02005081
40 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion Unknown status NCT01292252
41 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284
42 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
43 Balance Chiropractic Therapy for Cervical Spondylotic Radiculopathy Unknown status NCT02705131
44 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
45 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379
46 Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion Unknown status NCT02317185
47 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
48 Dynesys Spinal System Post Market 522 Study Unknown status NCT01528072
49 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766
50 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473

Search NIH Clinical Center for Spondylosis

Cochrane evidence based reviews: spondylosis

Genetic Tests for Spondylosis

Anatomical Context for Spondylosis

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylosis:

18
Vertebral Column

MalaCards organs/tissues related to Spondylosis:

38
Spinal Cord, Bone, Bone Marrow, Testes, Brain, Cortex, Dorsal Root Ganglion

Publications for Spondylosis

Articles related to Spondylosis:

(show top 50) (show all 618)
# Title Authors Year
1
Risk factors for non-fusion segment disease after anterior cervical spondylosis surgery: a retrospective study with long-term follow-up of 171 patients. ( 29394936 )
2018
2
Changes and significance of inflammatory cytokines in a rat model of cervical spondylosis. ( 29387194 )
2018
3
Apparent C8-T1 radiculopathy with hand weakness due to mid-cervical spondylosis. ( 29097135 )
2018
4
Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study. ( 29354237 )
2018
5
The effectiveness of anterior cervical decompression and fusion for the relief of dizziness in patients with cervical spondylosis: a multicentre prospective cohort study. ( 29305455 )
2018
6
Exploration about changes of IL-10, NF-I_B and MMP-3 in a rat model of cervical spondylosis. ( 29197741 )
2018
7
Radiologic indicators for prediction of difficult laryngoscopy in patients with cervical spondylosis. ( 29388207 )
2018
8
Myelopathy after cervical disc arthroplasty due to progression of spondylosis at the index level: case report. ( 29393833 )
2018
9
Wet cupping therapy improves local blood perfusion and analgesic effects in patients with nerve-root type cervical spondylosis. ( 29340888 )
2018
10
Reliability and validity of CODA motion analysis system for measuring cervical range of motion in patients with cervical spondylosis and anterior cervical fusion. ( 29285065 )
2017
11
Efficacy of cortico/cancellous composite allograft in treatment of cervical spondylosis. ( 28816974 )
2017
12
The association between multiple sclerosis and spondylosis: When and why. ( 28629570 )
2017
13
Vertical spinal instability and cervical spondylosis: Is it focal or multisegmental? ( 29021665 )
2017
14
Surgical treatment of multilevel cervical spondylosis in patients with or without a history of syringomyelia. ( 28190207 )
2017
15
Relationship between the small cervical vertebral body and the morbidity of cervical spondylosis. ( 28767572 )
2017
16
Comments for radiological study of C3-C4 level surgical cases of cervical spondylosis. ( 28761504 )
2017
17
Effectiveness of acupuncture in the management of cervical spondylosis: a meta-analysis. ( 29254308 )
2017
18
Abnormal central motor conduction at the upper but not lower limbs correlates with severe cervical spondylosis: discussion of an unexpected observation. ( 28382220 )
2017
19
Mid-term efficacy and safety of cervical disc arthroplasty versus fusion in cervical spondylosis: A systematic review and meta-analysis. ( 28357067 )
2017
20
Prevalence and Risk Factors for Lumbar Spondylosis and Its Association with Low Back Pain among Rural Korean Residents. ( 28061494 )
2017
21
Shikani Optical Stylet versus Macintosh Laryngoscope for Intubation in Patients Undergoing Surgery for Cervical Spondylosis: A Randomized Controlled Trial. ( 28139512 )
2017
22
Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis. ( 28667278 )
2017
23
Double crush syndrome caused by cervical spondylosis and vertebral artery loop. ( 28508239 )
2017
24
Safety and Efficacy Study of an Ozone Laser Combined Therapy Using Puncture Needle in the Treatment of Patients With Cervical Spondylosis. ( 28525469 )
2017
25
Comparison between zero-profile spacer and plate with cage in the treatment of single level cervical spondylosis. ( 29171978 )
2017
26
Patients' beliefs about diagnosis and treatment of cervical spondylosis with radiculopathy. ( 29063271 )
2017
27
The Effectiveness of Cervical Spondylosis Therapy with Saunders Traction Device and High-Intensity Laser Therapy: A Randomized Controlled Trial. ( 28104903 )
2017
28
Complications and Mortality Following One to Two-Level Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 80 Years of Age. ( 28441681 )
2017
29
ACDF vs TDR for patients with cervical spondylosis - an 8A year follow up study. ( 29183306 )
2017
30
Surgical interventions for cervical spondylosis due to ossification of posterior longitudinal ligament: A meta-analysis. ( 28816942 )
2017
31
Clinical and Radiological Analysis of Bryan Cervical Artificial Disc Replacement for "Skip" Multi-Segment Cervical Spondylosis: Long-Term Follow-Up Results. ( 29101314 )
2017
32
Neck circumference to inter-incisor gap ratio: a new predictor of difficult laryngoscopy in cervical spondylosis patients. ( 28376741 )
2017
33
Multilevel cervical myelopathy due to cervical spondylosis/ossification of posterior longitudinal ligament-A complex problem. ( 26754985 )
2016
34
Transforaminal lumbar interbody fusion versus posterolateral fusion in degenerative lumbar spondylosis: A meta-analysis. ( 27749558 )
2016
35
Effect of Anterior Cervical Discectomy and Fusion on Patients with Atypical Symptoms Related to Cervical Spondylosis. ( 27168319 )
2016
36
Delayed diagnosed intermuscular lipoma causing a posterior interosseous nerve palsy in a patient with cervical spondylosis: the "priceless" value of the clinical examination in the technological era. ( 27142825 )
2016
37
The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. ( 26834465 )
2016
38
Comparison of a Stand-Alone Anchored Spacer Versus Plate-Cage Construct in the Treatment of Two Noncontiguous Levels of Cervical Spondylosis: A Preliminary Investigation. ( 26868426 )
2016
39
Update: Osteoarthritis and spondylosis, active component, U.S. Armed Forces, 2010-2015. ( 27682629 )
2016
40
Comparison of pedicle screw-based dynamic stabilization and fusion surgery in the treatment of radiographic adjacent-segment degeneration: a retrospective analysis of single L5-S1 degenerative spondylosis covering 4 years. ( 27341057 )
2016
41
Ultrasound-guided high-thoracic paravertebral block relieves referred pain caused by cervical spondylosis and provides stellate ganglion-blocking effect. ( 27687436 )
2016
42
Acute compressive myelopathy caused by spinal subarachnoid hemorrhage: a combined effect of asymptomatic cervical spondylosis. ( 27567572 )
2016
43
Spondylosis in a green moray eel, Gymnothorax funebris (Ranzani 1839), with swim bladder hyperinflation. ( 27734503 )
2016
44
The value of preoperative magnetic resonance imaging in predicting postoperative recovery in patients with cervical spondylosis myelopathy: a meta-analysis. ( 27074180 )
2016
45
A Comparison of Zero-Profile Devices and Artificial Cervical Disks in Patients With 2 Noncontiguous Levels of Cervical Spondylosis. ( 26889993 )
2016
46
Comparisons of Safety and Clinical Outcomes Between Multiple-level and Single-level Cervical Disk Replacement for Cervical Spondylosis: A Systematic Review and Meta-analysis. ( 27322653 )
2016
47
Treatment of degenerative cervical spondylosis with radiculopathy. Clinical practice guidelines endorsed by The Polish Society of Spinal Surgery. ( 26969567 )
2016
48
Treatment of Single-Level Cervical Spondylosis: Cervical Disk Arthroplasty Versus Anterior Cervical Decompression and Fusion. ( 27992641 )
2016
49
Positional Occlusion of Vertebral Artery Due to Cervical Spondylosis as Rare Cause of Wake-up Stroke: Report of Two Cases. ( 27890763 )
2016
50
A comparison of the effects of Mulligan's mobilization and Kinesio taping on pain, range of motion, muscle strength, and neck disability in patients with cervical spondylosis: A randomized controlled study1. ( 27257980 )
2016

Variations for Spondylosis

Expression for Spondylosis

Search GEO for disease gene expression data for Spondylosis.

Pathways for Spondylosis

GO Terms for Spondylosis

Cellular components related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 ENO2 HTRA1 IL1B KL PTH S100B

Biological processes related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of MAP kinase activity GO:0043407 9.26 HMGCR IL1B
2 positive regulation of bone mineralization GO:0030501 9.16 KL PTH
3 aging GO:0007568 9.13 HMGCR KL WRN
4 mammary gland branching involved in pregnancy GO:0060745 8.62 ESR1 VDR

Molecular functions related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 8.62 ESR1 VDR

Sources for Spondylosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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