MCID: SPN020
MIFTS: 48

Spondylosis malady

Categories: Bone diseases, Neuronal diseases

Aliases & Classifications for Spondylosis

Aliases & Descriptions for Spondylosis:

Name: Spondylosis 12 42 14 69
Spondylogenic Compression of Thoracic Spinal Cord 12
Spondylogenic Compression of Lumbar Spinal Cord 12
Thoracic or Lumbar Spondylosis with Myelopathy 12
Lumbosacral Spondylosis Without Myelopathy 12
Lumbar Spondylosis with Myelopathy 12
Spondylosis with Myelopathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2247
ICD10 33 M47 M47.9
ICD9CM 35 721.9
MeSH 42 D055009
UMLS 69 C0038019

Summaries for Spondylosis

Disease Ontology : 12 An bone structure disease that involves degeneration between vertebra located in vertebral column.

MalaCards based summary : Spondylosis, also known as spondylogenic compression of thoracic spinal cord, is related to central cord syndrome and carasil syndrome. An important gene associated with Spondylosis is S100B (S100 Calcium Binding Protein B), and among its related pathways/superpathways are Development_Hedgehog and PTH signaling pathways in bone and cartilage development and Endocrine and other factor-regulated calcium reabsorption. The drugs Dexamethasone and Pregabalin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and cortex, and related phenotypes are growth/size/body region and cardiovascular system

Wikipedia : 71 Spondylosis (from Ancient Greek σπόνδυλος spóndylos, \"a vertebra\", in plural \"vertebrae –... more...

Related Diseases for Spondylosis

Diseases related to Spondylosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 100)
id Related Disease Score Top Affiliating Genes
1 central cord syndrome 11.1
2 carasil syndrome 10.9
3 cervicitis 10.8
4 spinal cord disease 10.8
5 ethmoid sinus cancer 10.2 IL1B VDR
6 y chromosome detection 10.2 PTH VDR
7 waardenburg syndrome, type 4b 10.2 PTH VDR
8 strabismus 10.2 PTH S100B
9 porokeratosis 3, disseminated superficial actinic 10.2 HMGCR IL1B
10 myelinoclastic diffuse sclerosis 10.2 ENO2 S100B
11 benign schwannoma 10.2 ENO2 S100B
12 warthin tumor 10.2 ESR1 IL1B
13 orbit lymphoma 10.2 KL PTH
14 vulvar squamous papilloma 10.2 ESR1 S100B
15 central nervous system mature teratoma 10.2 ESR1 S100B
16 piussan lenaerts mathieu syndrome 10.2 ENO2 S100B
17 skin glomus tumor 10.2 ENO2 S100B
18 afibrinogenemia 10.2 ESR1 VDR
19 pediculus humanus corporis infestation 10.2 ENO2 S100B
20 carbuncle 10.1 ESR1 IL1B
21 urea cycle disorder 10.1 IL1B S100B
22 larynx leiomyoma 10.1 ESR1 IL1B
23 acrodermatitis enteropathica 10.1 HELLS WRN
24 ampulla of vater mucinous adenocarcinoma 10.1 ENO2 S100B
25 acrorenal syndrome 10.1 PTH VDR
26 pes anserinus tendinitis or bursitis 10.1 PTH VDR
27 uterine corpus leiomyomatosis 10.1 ENO2 S100B
28 breast reconstruction 10.1 ENO2 IL1B S100B
29 chronic myocardial ischemia 10.1 HMGCR PTH VDR
30 coffin-lowry syndrome 10.1 KL PTH VDR
31 gastric antral vascular ectasia 10.1 KL PTH VDR
32 weill-marchesani syndrome 10.1 KL PTH VDR
33 indian tick typhus 10.1 KL PTH VDR
34 allergic urticaria 10.1 KL PTH VDR
35 vulvar alveolar soft part sarcoma 10.0 ENO2 ESR1
36 childhood brain germinoma 10.0 ENO2 S100B
37 dysbaric osteonecrosis 10.0 ESR1 PTH VDR
38 ischemic bone disease 10.0 ESR1 PTH VDR
39 back pain 10.0
40 osteoarthritis 10.0
41 syringomyelia 10.0
42 radiculopathy 10.0
43 baller-gerold syndrome 10.0 HELLS WRN
44 spinal cord injury 9.9
45 hyperostosis 9.9
46 migraine with aura 9.9 ESR1 IL1B
47 dysphagia 9.9
48 spondylolisthesis 9.9
49 diffuse idiopathic skeletal hyperostosis 9.9
50 myocardial infarction 9.8 ESR1 HMGCR IL1B S100B

Comorbidity relations with Spondylosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Spondylosis:



Diseases related to Spondylosis

Symptoms & Phenotypes for Spondylosis

MGI Mouse Phenotypes related to Spondylosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.06 ENO2 ESR1 HELLS HMGCR HTRA1 KL
2 cardiovascular system MP:0005385 10 HTRA1 IL1B KL PTH VDR WRN
3 homeostasis/metabolism MP:0005376 9.97 ESR1 HELLS HMGCR IL1B KL PTH
4 endocrine/exocrine gland MP:0005379 9.91 ESR1 HELLS KL PTH VDR WRN
5 hematopoietic system MP:0005397 9.91 ESR1 HELLS IL1B KL PTH VDR
6 immune system MP:0005387 9.8 ESR1 HELLS IL1B KL PTH VDR
7 integument MP:0010771 9.7 ESR1 HELLS IL1B KL S100B VDR
8 limbs/digits/tail MP:0005371 9.43 PTH VDR WRN ESR1 HELLS KL
9 skeleton MP:0005390 9.23 ESR1 HELLS HTRA1 IL1B KL PTH

Drugs & Therapeutics for Spondylosis

Drugs for Spondylosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 102)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
2
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
3
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
4
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
5
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
6
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
7 BB 1101 Phase 4,Phase 2
8 Dexamethasone 21-phosphate Phase 4,Phase 2
9 Dexamethasone acetate Phase 4,Phase 2 1177-87-3
10 Analgesics Phase 4,Phase 2,Phase 3
11 Anti-Anxiety Agents Phase 4
12 Anticonvulsants Phase 4
13 calcium channel blockers Phase 4
14 Calcium, Dietary Phase 4
15 Central Nervous System Depressants Phase 4,Phase 2,Phase 3
16 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
17 Psychotropic Drugs Phase 4
18 Tranquilizing Agents Phase 4
19 Anesthetics Phase 4,Phase 2,Phase 3
20 Anesthetics, Local Phase 4,Phase 2
21 Anti-Arrhythmia Agents Phase 4
22 Anti-Inflammatory Agents Phase 4,Phase 2
23 Diuretics, Potassium Sparing Phase 4
24 glucocorticoids Phase 4
25 Hormone Antagonists Phase 4
26 Hormones Phase 4
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
28 Immunosuppressive Agents Phase 4
29 Sodium Channel Blockers Phase 4
30 triamcinolone acetonide Phase 4
31 Triamcinolone diacetate Phase 4
32 Triamcinolone hexacetonide Phase 4
33 Analgesics, Opioid Phase 4
34 Anesthetics, Dissociative Phase 4
35 Anesthetics, General Phase 4
36 Anesthetics, Intravenous Phase 4
37 Excitatory Amino Acid Antagonists Phase 4
38 Excitatory Amino Acids Phase 4
39 Narcotics Phase 4,Phase 2
40 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
41
s 1 (combination) Phase 4,Phase 1,Phase 2
42 Antiemetics Phase 4
43 Antineoplastic Agents, Hormonal Phase 4
44 Autonomic Agents Phase 4
45 Gastrointestinal Agents Phase 4
46 HIV Protease Inhibitors Phase 4
47
protease inhibitors Phase 4
48
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
49 Hypnotics and Sedatives Phase 2, Phase 3
50 Adrenergic Agents Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 152)
id Name Status NCT ID Phase
1 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4
2 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4
3 Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy Completed NCT00285337 Phase 4
4 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
5 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4
6 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
7 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
8 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4
9 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
10 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
11 Comparison of Complication Rates Between Lateral Approaches to the Lumbar Spine Enrolling by invitation NCT02068729 Phase 4
12 Particulate Corticosteroid Versus Non-particulate Corticosteroid for Sacroiliac Joint Injection Not yet recruiting NCT03166761 Phase 4
13 Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis Terminated NCT01560273 Phase 4
14 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
15 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
16 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
17 The CSM Trial: A Multicenter Study Comparing Ventral to Dorsal Surgery for Cervical Spondylotic Myelopathy Completed NCT00506558 Phase 3
18 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
19 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
20 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
21 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Recruiting NCT02854904 Phase 2, Phase 3
22 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
23 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
24 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
25 Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain Completed NCT00587626 Phase 2
26 Effect of Cervical Collar in Cervical Radicular Pain. Completed NCT00395798 Phase 2
27 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
29 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
30 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
31 Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery Recruiting NCT02276911 Phase 2
32 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
33 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
34 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Not yet recruiting NCT02884440 Phase 2
35 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
36 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
37 The CX-DZ-Ⅱ Intelligent Electroacupuncture Instrument for Neck Pain Not yet recruiting NCT03005301 Phase 1
38 Study on the Early Warning and Treatment of Cervical Spondylosis of Cervical Type on Young People Based on the " Move Generate Yang " Theory Unknown status NCT02199405
39 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284
40 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
41 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
42 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379
43 Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion Unknown status NCT02317185
44 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
45 Effects of Exercise Intervention on Patients With Low Back Pain Due to Spondylolytic Spondylolisthesis. Unknown status NCT01985776
46 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766
47 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473
48 A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis Completed NCT01243684
49 DTI of the Brain and Cervical Spine: Evaluation in Normal Subjects and Patients With Cervical Spondylotic Myelopathy Completed NCT01868958
50 Prospective Clinical Evaluation of the New Aegis Plate for Anterior Interbody Fusions Completed NCT00555659

Search NIH Clinical Center for Spondylosis

Cochrane evidence based reviews: spondylosis

Genetic Tests for Spondylosis

Anatomical Context for Spondylosis

MalaCards organs/tissues related to Spondylosis:

39
Spinal Cord, Bone, Cortex, Testes, Dorsal Root Ganglion

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylosis:

18
Vertebral Column

Publications for Spondylosis

Articles related to Spondylosis:

(show top 50) (show all 587)
id Title Authors Year
1
Prevalence and Risk Factors for Lumbar Spondylosis and Its Association with Low Back Pain among Rural Korean Residents. ( 28061494 )
2017
2
Effects of decompressive cervical surgery on blood pressure in cervical spondylosis patients with hypertension: a time series cohort study. ( 26738624 )
2016
3
Anterior cervical discectomy and fusion versus cervical arthroplasty for the management of cervical spondylosis: a meta-analysis. ( 27771787 )
2016
4
Spondylosis in a green moray eel, Gymnothorax funebris (Ranzani 1839), with swim bladder hyperinflation. ( 27734503 )
2016
5
A comparison of the effects of Mulligan's mobilization and Kinesio taping on pain, range of motion, muscle strength, and neck disability in patients with cervical spondylosis: A randomized controlled study1. ( 27257980 )
2016
6
Acute compressive myelopathy caused by spinal subarachnoid hemorrhage: a combined effect of asymptomatic cervical spondylosis. ( 27567572 )
2016
7
Age-Related Incidence of Cervical Spondylosis in Residents of Jeju Island. ( 27790313 )
2016
8
Update: Osteoarthritis and spondylosis, active component, U.S. Armed Forces, 2010-2015. ( 27682629 )
2016
9
Transforaminal lumbar interbody fusion versus posterolateral fusion in degenerative lumbar spondylosis: A meta-analysis. ( 27749558 )
2016
10
Prevalence of lumbar spondylosis and its association with low back pain among community-dwelling Japanese women. ( 27905911 )
2016
11
Effectiveness and safety of Mobi-C for treatment of single-level cervical disc spondylosis: a randomised control trial with a minimum of five years of follow-up. ( 27235528 )
2016
12
Comparisons of Safety and Clinical Outcomes Between Multiple-level and Single-level Cervical Disk Replacement for Cervical Spondylosis: A Systematic Review and Meta-analysis. ( 27322653 )
2016
13
Venous hypertensive myelopathy associated with cervical spondylosis. ( 27293119 )
2016
14
Lumbar spondylosis, lumbar spinal stenosis, knee pain, back muscle strength are associated with the locomotive syndrome: Rural population study in Japan. ( 27021251 )
2016
15
Delayed diagnosed intermuscular lipoma causing a posterior interosseous nerve palsy in a patient with cervical spondylosis: the "priceless" value of the clinical examination in the technological era. ( 27142825 )
2016
16
Positional Occlusion of Vertebral Artery Due to Cervical Spondylosis as Rare Cause of Wake-up Stroke: Report of Two Cases. ( 27890763 )
2016
17
Multilevel cervical myelopathy due to cervical spondylosis/ossification of posterior longitudinal ligament-A complex problem. ( 26754985 )
2016
18
Difference in prevalence of cervical spondylosis in Muslim population who perform NAMAZ > 4 time a day who perform NAMAZ infrequently. ( 27728680 )
2016
19
Treatment of Single-Level Cervical Spondylosis: Cervical Disk Arthroplasty Versus Anterior Cervical Decompression and Fusion. ( 27992641 )
2016
20
Atypical symptoms in patients with cervical spondylosis might be the result of stimulation on the dura mater and spinal cord. ( 27142142 )
2016
21
The value of preoperative magnetic resonance imaging in predicting postoperative recovery in patients with cervical spondylosis myelopathy: a meta-analysis. ( 27074180 )
2016
22
Comparison of a Stand-Alone Anchored Spacer Versus Plate-Cage Construct in the Treatment of Two Noncontiguous Levels of Cervical Spondylosis: A Preliminary Investigation. ( 26868426 )
2016
23
Comparison of pedicle screw-based dynamic stabilization and fusion surgery in the treatment of radiographic adjacent-segment degeneration: a retrospective analysis of single L5-S1 degenerative spondylosis covering 4 years. ( 27341057 )
2016
24
Ultrasound-guided high-thoracic paravertebral block relieves referred pain caused by cervical spondylosis and provides stellate ganglion-blocking effect. ( 27687436 )
2016
25
Effect of Anterior Cervical Discectomy and Fusion on Patients with Atypical Symptoms Related to Cervical Spondylosis. ( 27168319 )
2016
26
Readmission Rates, Reasons, and Risk Factors Following Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 65 Years of Age. ( 27120061 )
2016
27
The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. ( 26834465 )
2016
28
Treatment of degenerative cervical spondylosis with radiculopathy. Clinical practice guidelines endorsed by The Polish Society of Spinal Surgery. ( 26969567 )
2016
29
Pulse changes in patients with cervical spondylosis before and after acupuncture treatment. ( 26946621 )
2016
30
A Comparison of Zero-Profile Devices and Artificial Cervical Disks in Patients With 2 Noncontiguous Levels of Cervical Spondylosis. ( 26889993 )
2016
31
The Kinematics and Spondylosis of the Lumbar Spine Vary Depending on the Levels of Motion Segments in Individuals with Low Back Pain. ( 27831966 )
2016
32
Radiological study of C3-C4 level surgical cases of cervical spondylosis. ( 27366255 )
2016
33
Low Back Pain and Spondylosis. ( 27704501 )
2016
34
The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification. ( 26162813 )
2015
35
Comparison of zero-profile anchored spacer versus plate-cage construct in treatment of cervical spondylosis with regard to clinical outcomes and incidence of major complications: a meta-analysis. ( 26445543 )
2015
36
Hemorrhagic Retinopathy after Spondylosis Surgery and Seizure. ( 26099062 )
2015
37
Preliminary Experiences of the Combined Midline-Splitting French Door Laminoplasty with Polyether Ether Ketone (PEEK) Plate for Cervical Spondylosis and OPLL. ( 26217382 )
2015
38
Persistent Outpatient Hypertension is Independently Associated with Spinal Cord Dysfunction and Imaging Characteristics of Spinal Cord Damage among Patients with Cervical Spondylosis. ( 25819526 )
2015
39
Serum pentosidine concentration is associated with radiographic severity of lumbar spondylosis in a general Japanese population. ( 26661661 )
2015
40
Relationship between paraspinal muscle cross-sectional area and relative proprioceptive weighting ratio of older persons with lumbar spondylosis. ( 26311962 )
2015
41
Neuromyelitis Optica Spectrum Disorder Associated with Cervical Spondylosis. ( 26608996 )
2015
42
Correlation of force control with regional spinal DTI in patients with cervical spondylosis without signs of spinal cord injury on conventional MRI. ( 26123409 )
2015
43
Outcomes of extended transforaminal lumbar interbody fusion for lumbar spondylosis. ( 26358199 )
2015
44
Effect Of Naturopathy Treatments And Yogic Practices On Cervical Spondylosis--A Case Report. ( 27530013 )
2015
45
Clinical study of C3-C4 level surgical cases of cervical spondylosis. ( 26005164 )
2015
46
Subaxial cervical spine involvement in symptomatic rheumatoid arthritis patients: Comparison with cervical spondylosis. ( 25841801 )
2015
47
Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis. ( 25678792 )
2015
48
Zero-profile implant versus conventional cage-plate implant in anterior cervical discectomy and fusion for the treatment of degenerative cervical spondylosis: a meta-analysis. ( 26381236 )
2015
49
Localizing value of pain distribution patterns in cervical spondylosis. ( 25901232 )
2015
50
Anterior cervical discectomy with arthroplasty versus anterior cervical discectomy and fusion for cervical spondylosis. ( 25533051 )
2015

Variations for Spondylosis

Expression for Spondylosis

Search GEO for disease gene expression data for Spondylosis.

Pathways for Spondylosis

GO Terms for Spondylosis

Cellular components related to Spondylosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 ENO2 HTRA1 IL1B KL PTH S100B

Biological processes related to Spondylosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of MAP kinase activity GO:0043407 9.26 HMGCR IL1B
2 positive regulation of bone mineralization GO:0030501 9.16 KL PTH
3 aging GO:0007568 9.13 HMGCR KL WRN
4 mammary gland branching involved in pregnancy GO:0060745 8.62 ESR1 VDR

Molecular functions related to Spondylosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879 8.62 ESR1 VDR

Sources for Spondylosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....