MCID: SPN020
MIFTS: 46

Spondylosis

Categories: Bone diseases, Neuronal diseases

Aliases & Classifications for Spondylosis

MalaCards integrated aliases for Spondylosis:

Name: Spondylosis 12 42 14 69
Spondylogenic Compression of Thoracic Spinal Cord 12
Spondylogenic Compression of Lumbar Spinal Cord 12
Thoracic or Lumbar Spondylosis with Myelopathy 12
Lumbosacral Spondylosis Without Myelopathy 12
Lumbar Spondylosis with Myelopathy 12
Spondylosis with Myelopathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2247
ICD10 33 M47 M47.9
ICD9CM 35 721.9
MeSH 42 D055009
UMLS 69 C0038019

Summaries for Spondylosis

Disease Ontology : 12 An bone structure disease that involves degeneration between vertebra located in vertebral column.

MalaCards based summary : Spondylosis, also known as spondylogenic compression of thoracic spinal cord, is related to motor neuron disease and central cord syndrome. An important gene associated with Spondylosis is HTRA1 (HtrA Serine Peptidase 1), and among its related pathways/superpathways are Development_Hedgehog and PTH signaling pathways in bone and cartilage development and Endocrine and other factor-regulated calcium reabsorption. The drugs Dexamethasone and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and bone marrow, and related phenotypes are growth/size/body region and cardiovascular system

Wikipedia : 72 Spondylosis (from Ancient Greek σπόνδυλος spóndylos, \"a vertebra\", in plural \"vertebrae – the... more...

Related Diseases for Spondylosis

Diseases related to Spondylosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
id Related Disease Score Top Affiliating Genes
1 motor neuron disease 30.5 ENO2 S100B
2 central cord syndrome 11.1
3 carasil syndrome 10.9
4 cervicitis 10.9
5 spinal cord disease 10.8
6 spastic paraplegia 25 10.8
7 meningitis and encephalitis 10.7 ENO2 S100B
8 benallegue lacete syndrome 10.7 ENO2 S100B
9 myoma 10.7 ENO2 S100B
10 enteric pattern testicular yolk sac tumor 10.7 ENO2 S100B
11 hydromyelia 10.7 ENO2 S100B
12 pituitary dwarfism with large sella turcica 10.7 ENO2 S100B
13 pediatric ependymoma 10.7 ENO2 S100B
14 mixed epithelial stromal tumour 10.6 ENO2 S100B
15 phobic disorder 10.6 ENO2 S100B
16 skin glomus tumor 10.6 ENO2 S100B
17 anal canal adenocarcinoma 10.6 ENO2 S100B
18 vulvar keratoacanthoma-like carcinoma 10.6 ENO2 S100B
19 ulcerative colitis 10.6 ENO2 S100B
20 cervical adenomyoma 10.6 ENO2 S100B
21 ethmoid sinus cancer 10.5 IL1B VDR
22 pulmonary immaturity 10.5 ENO2 S100B
23 brain angioma 10.5 PTH S100B
24 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.5 ENO2 S100B
25 brain meningioma 10.5 ENO2 S100B
26 anal canal squamous cell carcinoma 10.5 ENO2 PTH
27 urethra clear cell adenocarcinoma 10.5 ENO2 ESR1
28 white sponge nevus of cannon, krt4-related 10.5 PTH VDR
29 vulvar squamous papilloma 10.4 ESR1 S100B
30 sternum cancer 10.4 ENO2 S100B
31 walker dyson syndrome 10.4 ESR1 IL1B
32 hypersensitivity reaction type iii disease 10.4 ENO2 ESR1
33 waardenburg syndrome, type 4b 10.4 PTH VDR
34 silver-russell syndrome due to 11p15 microduplication 10.4 IL1B VDR
35 subglottis neoplasm 10.4 ESR1 IL1B
36 carbuncle 10.4 ESR1 IL1B
37 hip subluxation 10.4 ESR1 S100B
38 dextrocardia with situs inversus 10.4 ENO2 S100B
39 baller-gerold syndrome 10.4 HELLS WRN
40 adult neuronal ceroid lipofuscinosis 10.4 ESR1 VDR
41 bacillary angiomatosis 10.4 PTH VDR
42 ampulla of vater neoplasm 10.3 ESR1 IL1B
43 pes anserinus tendinitis or bursitis 10.3 PTH VDR
44 vacterl association 10.3 IL1B VDR
45 opioid abuse 10.3 PTH VDR
46 progressive relapsing multiple sclerosis 10.3 ENO2 S100B
47 epileptic encephalopathy, early infantile, 7 10.3 IL1B VDR
48 rapadilino syndrome 10.3 HELLS WRN
49 tinea unguium 10.3 PTH VDR
50 breast disease 10.2 ESR1 IL1B

Comorbidity relations with Spondylosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Spondylosis:



Diseases related to Spondylosis

Symptoms & Phenotypes for Spondylosis

MGI Mouse Phenotypes related to Spondylosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.02 ENO2 ESR1 HELLS HMGCR HTRA1 KL
2 cardiovascular system MP:0005385 10 ESR1 HTRA1 IL1B KL PTH VDR
3 homeostasis/metabolism MP:0005376 9.91 PTH S100B VDR WRN ESR1 HELLS
4 endocrine/exocrine gland MP:0005379 9.88 ESR1 HELLS KL PTH VDR WRN
5 hematopoietic system MP:0005397 9.87 ESR1 HELLS IL1B KL PTH VDR
6 craniofacial MP:0005382 9.73 ENO2 PTH VDR WRN
7 integument MP:0010771 9.7 ESR1 HELLS IL1B KL S100B VDR
8 limbs/digits/tail MP:0005371 9.43 ESR1 HELLS KL PTH VDR WRN
9 skeleton MP:0005390 9.23 VDR WRN ESR1 HELLS HTRA1 IL1B

Drugs & Therapeutics for Spondylosis

Drugs for Spondylosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 101)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
2
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
3
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
4
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
5
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
6
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
7
Menthol Approved Phase 4 2216-51-5 16666
8 Dexamethasone acetate Phase 4,Phase 2 1177-87-3
9 BB 1101 Phase 4,Phase 2
10 triamcinolone acetonide Phase 4
11 Analgesics Phase 4,Phase 2,Phase 3
12 calcium channel blockers Phase 4
13 glucocorticoids Phase 4
14 Central Nervous System Depressants Phase 4,Phase 2,Phase 3
15 Narcotics Phase 4,Phase 2
16 Sodium Channel Blockers Phase 4
17 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
18 Analgesics, Opioid Phase 4
19 Anesthetics Phase 4,Phase 2,Phase 3
20 Hormone Antagonists Phase 4
21 Anesthetics, Dissociative Phase 4
22 Anesthetics, General Phase 4
23 Anesthetics, Intravenous Phase 4
24 Tranquilizing Agents Phase 4
25 Anesthetics, Local Phase 4,Phase 2
26 Triamcinolone diacetate Phase 4
27 Triamcinolone hexacetonide Phase 4
28 Hormones Phase 4
29 Diuretics, Potassium Sparing Phase 4
30 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
31 Anti-Anxiety Agents Phase 4
32 Anti-Arrhythmia Agents Phase 4
33 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
34 Excitatory Amino Acid Antagonists Phase 4
35 Excitatory Amino Acids Phase 4
36 Immunosuppressive Agents Phase 4
37 Anticonvulsants Phase 4
38 Anti-Inflammatory Agents Phase 4,Phase 2
39 Psychotropic Drugs Phase 4
40 Calcium, Dietary Phase 4
41
protease inhibitors Phase 4
42 Gastrointestinal Agents Phase 4
43 HIV Protease Inhibitors Phase 4
44 Antiemetics Phase 4
45 Autonomic Agents Phase 4
46 Antineoplastic Agents, Hormonal Phase 4
47
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
48 Hypnotics and Sedatives Phase 2, Phase 3
49 Adrenergic Agents Phase 2, Phase 3
50 Adrenergic Agonists Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 160)

id Name Status NCT ID Phase Drugs
1 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
2 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4 Triamcinolone 80mg
3 Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy Completed NCT00285337 Phase 4
4 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
5 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
6 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
7 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
8 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
9 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
10 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
11 Particulate Corticosteroid Versus Non-particulate Corticosteroid for Sacroiliac Joint Injection Enrolling by invitation NCT03166761 Phase 4 Dexamethasone;Triamcinolone Acetonide
12 Efficacy of Using Solum IV and BMC With GFC in TLIF Not yet recruiting NCT03223701 Phase 4
13 Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis Terminated NCT01560273 Phase 4
14 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
15 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
16 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
17 The CSM Trial: A Multicenter Study Comparing Ventral to Dorsal Surgery for Cervical Spondylotic Myelopathy Completed NCT00506558 Phase 3
18 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
19 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
20 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
21 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Recruiting NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
22 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
23 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
24 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
25 Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain Completed NCT00587626 Phase 2
26 Effect of Cervical Collar in Cervical Radicular Pain. Completed NCT00395798 Phase 2
27 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
29 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
30 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
31 Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery Recruiting NCT02276911 Phase 2 Ibuprofen
32 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
33 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
34 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
35 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
36 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
37 The CX-DZ-Ⅱ Intelligent Electroacupuncture Instrument for Neck Pain Not yet recruiting NCT03005301 Phase 1
38 Study on the Early Warning and Treatment of Cervical Spondylosis of Cervical Type on Young People Based on the " Move Generate Yang " Theory Unknown status NCT02199405
39 Baxter: Actifuse SHAPE vs DBX in ACC Unknown status NCT02005081
40 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284
41 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
42 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
43 Lumbar Fusion With The Icotec CF/PEEK Pedicle System In Combination With The Icotec CF/PEEK TLIF Cage ETurn™ Unknown status NCT02087267
44 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379
45 Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion Unknown status NCT02317185
46 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
47 Effects of Exercise Intervention on Patients With Low Back Pain Due to Spondylolytic Spondylolisthesis. Unknown status NCT01985776
48 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766
49 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473
50 A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis Completed NCT01243684

Search NIH Clinical Center for Spondylosis

Cochrane evidence based reviews: spondylosis

Genetic Tests for Spondylosis

Anatomical Context for Spondylosis

MalaCards organs/tissues related to Spondylosis:

39
Spinal Cord, Bone, Bone Marrow, Testes, Brain, Cortex, Dorsal Root Ganglion

Publications for Spondylosis

Articles related to Spondylosis:

(show top 50) (show all 602)
id Title Authors Year
1
The association between multiple sclerosis and spondylosis: When and why. ( 28629570 )
2017
2
The Effectiveness of Cervical Spondylosis Therapy with Saunders Traction Device and High-Intensity Laser Therapy: A Randomized Controlled Trial. ( 28104903 )
2017
3
Surgical interventions for cervical spondylosis due to ossification of posterior longitudinal ligament: A meta-analysis. ( 28816942 )
2017
4
Comments for radiological study of C3-C4 level surgical cases of cervical spondylosis. ( 28761504 )
2017
5
Efficacy of cortico/cancellous composite allograft in treatment of cervical spondylosis. ( 28816974 )
2017
6
Neck circumference to inter-incisor gap ratio: a new predictor of difficult laryngoscopy in cervical spondylosis patients. ( 28376741 )
2017
7
Double crush syndrome caused by cervical spondylosis and vertebral artery loop. ( 28508239 )
2017
8
Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis. ( 28667278 )
2017
9
Surgical treatment of multilevel cervical spondylosis in patients with or without a history of syringomyelia. ( 28190207 )
2017
10
Mid-term efficacy and safety of cervical disc arthroplasty versus fusion in cervical spondylosis: A systematic review and meta-analysis. ( 28357067 )
2017
11
Prevalence and Risk Factors for Lumbar Spondylosis and Its Association with Low Back Pain among Rural Korean Residents. ( 28061494 )
2017
12
Complications and Mortality Following One to Two-Level Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 80 Years of Age. ( 28441681 )
2017
13
Shikani Optical Stylet versus Macintosh Laryngoscope for Intubation in Patients Undergoing Surgery for Cervical Spondylosis: A Randomized Controlled Trial. ( 28139512 )
2017
14
Relationship between the small cervical vertebral body and the morbidity of cervical spondylosis. ( 28767572 )
2017
15
Safety and Efficacy Study of an Ozone Laser Combined Therapy Using Puncture Needle in the Treatment of Patients With Cervical Spondylosis. ( 28525469 )
2017
16
Abnormal central motor conduction at the upper but not lower limbs correlates with severe cervical spondylosis: discussion of an unexpected observation. ( 28382220 )
2017
17
Comparison of pedicle screw-based dynamic stabilization and fusion surgery in the treatment of radiographic adjacent-segment degeneration: a retrospective analysis of single L5-S1 degenerative spondylosis covering 4 years. ( 27341057 )
2016
18
Atypical symptoms in patients with cervical spondylosis might be the result of stimulation on the dura mater and spinal cord. ( 27142142 )
2016
19
A Comparison of Zero-Profile Devices and Artificial Cervical Disks in Patients With 2 Noncontiguous Levels of Cervical Spondylosis. ( 26889993 )
2016
20
Anterior cervical discectomy and fusion versus cervical arthroplasty for the management of cervical spondylosis: a meta-analysis. ( 27771787 )
2016
21
Treatment of degenerative cervical spondylosis with radiculopathy. Clinical practice guidelines endorsed by The Polish Society of Spinal Surgery. ( 26969567 )
2016
22
Spondylosis in a green moray eel, Gymnothorax funebris (Ranzani 1839), with swim bladder hyperinflation. ( 27734503 )
2016
23
Lumbar spondylosis, lumbar spinal stenosis, knee pain, back muscle strength are associated with the locomotive syndrome: Rural population study in Japan. ( 27021251 )
2016
24
The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. ( 26834465 )
2016
25
Radiological study of C3-C4 level surgical cases of cervical spondylosis. ( 27366255 )
2016
26
Low Back Pain and Spondylosis. ( 27704501 )
2016
27
Acute compressive myelopathy caused by spinal subarachnoid hemorrhage: a combined effect of asymptomatic cervical spondylosis. ( 27567572 )
2016
28
The value of preoperative magnetic resonance imaging in predicting postoperative recovery in patients with cervical spondylosis myelopathy: a meta-analysis. ( 27074180 )
2016
29
Transforaminal lumbar interbody fusion versus posterolateral fusion in degenerative lumbar spondylosis: A meta-analysis. ( 27749558 )
2016
30
Prevalence of lumbar spondylosis and its association with low back pain among community-dwelling Japanese women. ( 27905911 )
2016
31
Readmission Rates, Reasons, and Risk Factors Following Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 65 Years of Age. ( 27120061 )
2016
32
Comparison of a Stand-Alone Anchored Spacer Versus Plate-Cage Construct in the Treatment of Two Noncontiguous Levels of Cervical Spondylosis: A Preliminary Investigation. ( 26868426 )
2016
33
Update: Osteoarthritis and spondylosis, active component, U.S. Armed Forces, 2010-2015. ( 27682629 )
2016
34
The Kinematics and Spondylosis of the Lumbar Spine Vary Depending on the Levels of Motion Segments in Individuals with Low Back Pain. ( 27831966 )
2016
35
Difference in prevalence of cervical spondylosis in Muslim population who perform NAMAZ > 4 time a day who perform NAMAZ infrequently. ( 27728680 )
2016
36
A comparison of the effects of Mulligan's mobilization and Kinesio taping on pain, range of motion, muscle strength, and neck disability in patients with cervical spondylosis: A randomized controlled study1. ( 27257980 )
2016
37
Venous hypertensive myelopathy associated with cervical spondylosis. ( 27293119 )
2016
38
Positional Occlusion of Vertebral Artery Due to Cervical Spondylosis as Rare Cause of Wake-up Stroke: Report of Two Cases. ( 27890763 )
2016
39
Pulse changes in patients with cervical spondylosis before and after acupuncture treatment. ( 26946621 )
2016
40
Effect of Anterior Cervical Discectomy and Fusion on Patients with Atypical Symptoms Related to Cervical Spondylosis. ( 27168319 )
2016
41
Effects of decompressive cervical surgery on blood pressure in cervical spondylosis patients with hypertension: a time series cohort study. ( 26738624 )
2016
42
Delayed diagnosed intermuscular lipoma causing a posterior interosseous nerve palsy in a patient with cervical spondylosis: the "priceless" value of the clinical examination in the technological era. ( 27142825 )
2016
43
Treatment of Single-Level Cervical Spondylosis: Cervical Disk Arthroplasty Versus Anterior Cervical Decompression and Fusion. ( 27992641 )
2016
44
Multilevel cervical myelopathy due to cervical spondylosis/ossification of posterior longitudinal ligament-A complex problem. ( 26754985 )
2016
45
Comparisons of Safety and Clinical Outcomes Between Multiple-level and Single-level Cervical Disk Replacement for Cervical Spondylosis: A Systematic Review and Meta-analysis. ( 27322653 )
2016
46
Ultrasound-guided high-thoracic paravertebral block relieves referred pain caused by cervical spondylosis and provides stellate ganglion-blocking effect. ( 27687436 )
2016
47
Age-Related Incidence of Cervical Spondylosis in Residents of Jeju Island. ( 27790313 )
2016
48
Effectiveness and safety of Mobi-C for treatment of single-level cervical disc spondylosis: a randomised control trial with a minimum of five years of follow-up. ( 27235528 )
2016
49
Serum pentosidine concentration is associated with radiographic severity of lumbar spondylosis in a general Japanese population. ( 26661661 )
2015
50
Effect Of Naturopathy Treatments And Yogic Practices On Cervical Spondylosis--A Case Report. ( 27530013 )
2015

Variations for Spondylosis

Expression for Spondylosis

Search GEO for disease gene expression data for Spondylosis.

Pathways for Spondylosis

GO Terms for Spondylosis

Cellular components related to Spondylosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 ENO2 HTRA1 IL1B KL PTH S100B

Biological processes related to Spondylosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of MAP kinase activity GO:0043407 9.26 HMGCR IL1B
2 positive regulation of bone mineralization GO:0030501 9.16 KL PTH
3 aging GO:0007568 9.13 HMGCR KL WRN
4 mammary gland branching involved in pregnancy GO:0060745 8.62 ESR1 VDR

Molecular functions related to Spondylosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879 8.62 ESR1 VDR

Sources for Spondylosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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