MCID: SPN340
MIFTS: 25

Spontaneous Intracranial Hypotension

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Spontaneous Intracranial Hypotension

MalaCards integrated aliases for Spontaneous Intracranial Hypotension:

Name: Spontaneous Intracranial Hypotension 56
Cerebrospinal Fluid Leak, Spontaneous 69
Spontaneous Cerebrospinal Fluid Leak 56
Intracranial Hypotension, Essential 69

Characteristics:

Orphanet epidemiological data:

56
spontaneous intracranial hypotension
Inheritance: Not applicable;

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Orphanet 56 ORPHA443180
UMLS via Orphanet 70 C3544264 C0751731 C3850067
ICD10 via Orphanet 34 G96.0

Summaries for Spontaneous Intracranial Hypotension

MalaCards based summary : Spontaneous Intracranial Hypotension, also known as cerebrospinal fluid leak, spontaneous, is related to intracranial hypotension and headache. The drugs Fibrin Tissue Adhesive and Coagulants have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and pituitary.

Wikipedia : 72 A spontaneous cerebrospinal fluid leak (SCSFL) is a medical condition in which the cerebrospinal fluid... more...

Related Diseases for Spontaneous Intracranial Hypotension

Diseases related to Spontaneous Intracranial Hypotension via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
id Related Disease Score Top Affiliating Genes
1 intracranial hypotension 11.0
2 headache 10.5
3 thrombosis 10.3
4 cerebritis 10.3
5 cerebrospinal fluid leak 10.3
6 cervicitis 10.1
7 neuropathy 10.0
8 intracranial hypertension 10.0
9 meningitis 10.0
10 aneurysm 10.0
11 siderosis 9.9
12 patulous eustachian tube 9.9
13 dementia 9.9
14 cranial nerve palsy 9.9
15 thunderclap headache 9.9
16 tremor 9.9
17 superficial siderosis 9.9
18 marfan syndrome 9.8
19 systemic lupus erythematosus 9.7
20 hyperprolactinemia 9.7
21 pituitary adenoma 9.7
22 anorexia nervosa 9.7
23 trigeminal neuralgia 9.7
24 bipolar disorder 9.7
25 hydrocephalus 9.7
26 osteoarthritis 9.7
27 sensorineural hearing loss 9.7
28 acute cervicitis 9.7
29 intracranial aneurysm 9.7
30 disseminated intravascular coagulation 9.7
31 aseptic meningitis 9.7
32 quadriplegia 9.7
33 ehlers-danlos syndrome 9.7
34 syringomyelia 9.7
35 sagittal sinus thrombosis 9.7
36 radiculopathy 9.7
37 strabismus 9.7
38 kidney disease 9.7
39 adenoma 9.7
40 lupus erythematosus 9.7
41 autosomal dominant polycystic kidney disease 9.7
42 meniere's disease 9.7
43 polycystic kidney disease 9.7
44 cough headache 9.7
45 ependymoma 9.7
46 tarlov cysts 9.7
47 abducens palsy 9.7
48 ataxia 9.7
49 encephalopathy 9.7

Graphical network of the top 20 diseases related to Spontaneous Intracranial Hypotension:



Diseases related to Spontaneous Intracranial Hypotension

Symptoms & Phenotypes for Spontaneous Intracranial Hypotension

Drugs & Therapeutics for Spontaneous Intracranial Hypotension

Drugs for Spontaneous Intracranial Hypotension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Fibrin Tissue Adhesive Phase 2
2 Coagulants Phase 2
3 Hemostatics Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment Not yet recruiting NCT03276975 Phase 2 TISSEEL
2 Spontaneous Intracranial Hypotension Treatment "SIHT" Recruiting NCT02261792
3 Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension Recruiting NCT03041441
4 Pituitary Function and Spontaneous Intracranial Hypotension Active, not recruiting NCT02603549

Search NIH Clinical Center for Spontaneous Intracranial Hypotension

Genetic Tests for Spontaneous Intracranial Hypotension

Anatomical Context for Spontaneous Intracranial Hypotension

MalaCards organs/tissues related to Spontaneous Intracranial Hypotension:

39
Brain, Spinal Cord, Pituitary, Kidney

Publications for Spontaneous Intracranial Hypotension

Articles related to Spontaneous Intracranial Hypotension:

(show top 50) (show all 431)
id Title Authors Year
1
Factors predicting response to the first epidural blood patch in spontaneous intracranial hypotension. ( 28043956 )
2017
2
Spontaneous Intracranial Hypotension Presenting as a "Pseudo-Chiari 1. ( 28357166 )
2017
3
Spontaneous Intracranial Hypotension after Vestibular Schwannoma Resection Due to an Unexpected Pathology: Tarlov Cysts. ( 28652945 )
2017
4
Simultaneous Surgical Decompression of Bilateral Subdural Hematoma and an Administration of Epidural Blood Patch for Spontaneous Intracranial Hypotension. ( 28538330 )
2017
5
Factors affecting cerebrospinal fluid opening pressure in patients with spontaneous intracranial hypotension. ( 28681582 )
2017
6
Comparison of the sagittal sinus cross-sectional area between patients with multiple sclerosis, hydrocephalus, intracranial hypertension and spontaneous intracranial hypotension: a surrogate marker of venous transmural pressure? ( 28679427 )
2017
7
Intracranial structural alteration predicts treatment outcome in patients with spontaneous intracranial hypotension. ( 28110544 )
2017
8
Quantitative Measurement of CSF in Patients with Spontaneous Intracranial Hypotension. ( 28385881 )
2017
9
Spontaneous Intracranial Hypotension With Site of Leak Detected Only After 111In-DTPA Cisternogram. ( 28079571 )
2017
10
Reversible Holmes' tremor due to spontaneous intracranial hypotension. ( 28754752 )
2017
11
Spinal meningeal diverticula, spontaneous intracranial hypotension, and superficial siderosis. ( 28130464 )
2017
12
Spontaneous intracranial hypotension diagnosed as Chiari I malformation. ( 28348118 )
2017
13
Value of Targeted Epidural Blood Patch and Management of Subdural Hematoma in Spontaneous Intracranial Hypotension: Case Report and Review of the Literature. ( 27693247 )
2017
14
Spontaneous Intracranial Hypotension: A Review and Introduction of an Algorithm For Management. ( 28192268 )
2017
15
Misdiagnosis of Spontaneous Intracranial Hypotension as a Risk Factor for Subdural Hematoma. ( 28653430 )
2017
16
Chiari-like displacement due to spontaneous intracranial hypotension in an adolescent: Successful treatment by epidural blood patch. ( 28283371 )
2017
17
Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension. ( 28755201 )
2017
18
Greater Occipital Nerve Treatment in the Management of Spontaneous Intracranial Hypotension Headache: A Case Report. ( 28466552 )
2017
19
The usefulness of MDCT-myelography for patients with spontaneous intracranial hypotension. ( 27104112 )
2016
20
Predictors of the Treatment Response of Spontaneous Intracranial Hypotension to an Epidural Blood Patch. ( 27149484 )
2016
21
Diagnosis and treatment of spontaneous intracranial hypotension due to cerebrospinal fluid leakage. ( 28066697 )
2016
22
Pearls & Oy-sters: Spontaneous intracranial hypotension and posterior reversible encephalopathy syndrome. ( 26857956 )
2016
23
Intraspinal hemorrhage in spontaneous intracranial hypotension: link to superficial siderosis? Report of 2 cases. ( 26588500 )
2016
24
A rare case of orthostatic headache due to spontaneous intracranial hypotension. ( 26862421 )
2016
25
Time-Dependent Changes in Dural Enhancement Associated With Spontaneous Intracranial Hypotension. ( 27557149 )
2016
26
Diskogenic microspurs as a major cause of intractable spontaneous intracranial hypotension. ( 27566748 )
2016
27
Spontaneous Intracranial Hypotension Treated with a Targeted CT-Guided Epidural Blood Patch. ( 26981128 )
2016
28
Early pain relief from orthostatic headache and hearing changes in spontaneous intracranial hypotension after epidural blood patch. ( 26908033 )
2016
29
Spontaneous intracranial hypotension with pseudo-subarachnoid hemorrhage. ( 26943460 )
2016
30
Venous infarction mimicking a neoplasm in spontaneous intracranial hypotension: an unusual cause of Parinaud's syndrome. ( 26987945 )
2016
31
Iterative epidural blood patch for recurrent spontaneous intracranial hypotension during pregnancy. ( 27687382 )
2016
32
Spontaneous intracranial hypotension caused by cervical CSF fistulae mimicking subarachnoid haemorrhage - a case report. ( 27341482 )
2016
33
Spontaneous intracranial hypotension complicated by malignancyinduced disseminated intravascular coagulation: A case report. ( 27854087 )
2016
34
Spontaneous intracranial hypotension syndrome: contribution of radioisotope cisternography. ( 27337940 )
2016
35
Epidural blood patch for spontaneous intracranial hypotension with chronic subdural haematoma: A case report and literature review. ( 27225863 )
2016
36
Spontaneous Intracranial Hypotension and its Association with Movement Disorders? ( 27897276 )
2016
37
Patterns of cerebrospinal fluid (CSF) distribution in patients with spontaneous intracranial hypotension: Assessed with magnetic resonance myelography. ( 27743810 )
2016
38
Granulomatosis With Polyangiitis-Associated Hypertrophic Pachymeningitis Mimicking Spontaneous Intracranial Hypotension: A Case Report. ( 27943273 )
2016
39
Oculomotor Palsy in Spontaneous Intracranial Hypotension: Case Report and Review of the Literature. ( 27670216 )
2016
40
Noncontrast Brain Computed Tomography Findings of Spontaneous Intracranial Hypotension in the Emergency Department Setting. ( 26763857 )
2016
41
Imaging Signs in Spontaneous Intracranial Hypotension: Prevalence and Relationship to CSF Pressure. ( 26869465 )
2016
42
Spontaneous intracranial hypotension following epidural anesthesia: a case report. ( 26939569 )
2016
43
Spontaneous Intracranial Hypotension: An Etiology for Consciousness Disorder and Coma. ( 27552236 )
2016
44
Clinical characteristics of 15 cases of chronic subdural hematomas due to spontaneous intracranial hypotension with spinal cerebrospinal fluid leak. ( 26769700 )
2016
45
Spontaneous Intracranial Hypotension Associated with Kinetic Tremor and Ataxia. ( 27351232 )
2016
46
A thin line between Meniere's disease and spontaneous intracranial hypotension syndrome. ( 26827704 )
2016
47
Management of spontaneous intracranial hypotension. ( 26837373 )
2016
48
Atypical Presentations of Intracranial Hypotension: Comparison with Classic Spontaneous Intracranial Hypotension. ( 26939631 )
2016
49
Myelographic Techniques for the Detection of Spinal CSF Leaks in Spontaneous Intracranial Hypotension. ( 26700332 )
2016
50
Successful Treatment of Spontaneous Intracranial Hypotension by Plugging the CSF Leak with Percutaneous Cyanoacrylate Injection: A Report of Two Cases. ( 27113404 )
2016

Variations for Spontaneous Intracranial Hypotension

Expression for Spontaneous Intracranial Hypotension

Search GEO for disease gene expression data for Spontaneous Intracranial Hypotension.

Pathways for Spontaneous Intracranial Hypotension

GO Terms for Spontaneous Intracranial Hypotension

Sources for Spontaneous Intracranial Hypotension

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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