MCID: SPN033
MIFTS: 25

Spontaneous Ocular Nystagmus malady

Neuronal diseases, Eye diseases categories

Aliases & Classifications for Spontaneous Ocular Nystagmus

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Aliases & Descriptions for Spontaneous Ocular Nystagmus:

Name: Spontaneous Ocular Nystagmus 10 12 65
Visual Deprivation Nystagmus 10
 
Searching Eye Movements 10
Ocular Nystagmus 10


Classifications:



External Ids:

Disease Ontology10 DOID:11771
MeSH36 D009759
ICD9CM29 379.53

Summaries for Spontaneous Ocular Nystagmus

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MalaCards based summary: Spontaneous Ocular Nystagmus, also known as visual deprivation nystagmus, is related to nephrosclerosis and otosalpingitis. An important gene associated with Spontaneous Ocular Nystagmus is FRMD7 (FERM Domain Containing 7), and among its related pathways are Glycogen Metabolism and Nur77 Signaling in T-Cell. Affiliated tissues include eye.

Related Diseases for Spontaneous Ocular Nystagmus

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Graphical network of the top 20 diseases related to Spontaneous Ocular Nystagmus:



Diseases related to spontaneous ocular nystagmus

Symptoms for Spontaneous Ocular Nystagmus

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Drugs & Therapeutics for Spontaneous Ocular Nystagmus

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Functional Link Between Hippocampal and Vestibular Systems: a Pilot Study in Epilepsy SurgeryActive, not recruitingNCT01285921
2Helpfulness of the Vibration Test Performed in Room Light on Clients With Inner Ear ProblemsEnrolling by invitationNCT02626052
3Safety and Feasibility of Using Epicall for Monitoring Pre-seizure BiomarkersNot yet recruitingNCT01436695

Search NIH Clinical Center for Spontaneous Ocular Nystagmus

Genetic Tests for Spontaneous Ocular Nystagmus

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Anatomical Context for Spontaneous Ocular Nystagmus

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MalaCards organs/tissues related to Spontaneous Ocular Nystagmus:

33
Eye

Animal Models for Spontaneous Ocular Nystagmus or affiliated genes

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Publications for Spontaneous Ocular Nystagmus

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Articles related to Spontaneous Ocular Nystagmus:

idTitleAuthorsYear
1
Ginkgolide B accelerates vestibular compensation of spontaneous ocular nystagmus in guinea pig following unilateral labyrinthectomy. (7895826)
1995
2
Injections of calmidazolium chloride into the ipsilateral medial vestibular nucleus or fourth ventricle reduce spontaneous ocular nystagmus following unilateral labyrinthectomy in guinea pigs. (8491266)
1993

Variations for Spontaneous Ocular Nystagmus

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Expression for genes affiliated with Spontaneous Ocular Nystagmus

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Search GEO for disease gene expression data for Spontaneous Ocular Nystagmus.

Pathways for genes affiliated with Spontaneous Ocular Nystagmus

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GO Terms for genes affiliated with Spontaneous Ocular Nystagmus

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Cellular components related to Spontaneous Ocular Nystagmus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sarcomereGO:00300179.8CALM1, CALM2
2calcium channel complexGO:00347049.7CALM1, CALM2
3spindle microtubuleGO:00058769.6CALM1, CALM2
4growth coneGO:00304269.2CALM1, CALM2, FRMD7

Biological processes related to Spontaneous Ocular Nystagmus according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of peptidyl-threonine phosphorylationGO:001080110.0CALM1, CALM2
2rhodopsin mediated signaling pathwayGO:001605610.0CALM1, CALM2
3regulation of rhodopsin mediated signaling pathwayGO:002240010.0CALM1, CALM2
4positive regulation of cyclic nucleotide metabolic processGO:003080110.0CALM1, CALM2
5positive regulation of protein autophosphorylationGO:003195410.0CALM1, CALM2
6regulation of cytokinesisGO:003246510.0CALM1, CALM2
7positive regulation of protein dephosphorylationGO:003530710.0CALM1, CALM2
8inositol phosphate metabolic processGO:004364710.0CALM1, CALM2
9positive regulation of cyclic-nucleotide phosphodiesterase activityGO:005134310.0CALM1, CALM2
10response to calcium ionGO:005159210.0CALM1, CALM2
11regulation of cardiac muscle contractionGO:005511710.0CALM1, CALM2
12positive regulation of ryanodine-sensitive calcium-release channel activityGO:006031610.0CALM1, CALM2
13regulation of high voltage-gated calcium channel activityGO:190184110.0CALM1, CALM2
14regulation of cell communication by electrical coupling involved in cardiac conductionGO:190184410.0CALM1, CALM2
15detection of calcium ionGO:000551310.0CALM1, CALM2
16negative regulation of ryanodine-sensitive calcium-release channel activityGO:00603159.9CALM1, CALM2
17positive regulation of phosphoprotein phosphatase activityGO:00325169.9CALM1, CALM2
18activation of phospholipase C activityGO:00072029.9CALM1, CALM2
19positive regulation of peptidyl-threonine phosphorylationGO:00108009.9CALM1, CALM2
20substantia nigra developmentGO:00217629.9CALM1, CALM2
21activation of adenylate cyclase activityGO:00071909.9CALM1, CALM2
22response to corticosteroneGO:00514129.9CALM1, CALM2
23glycogen catabolic processGO:00059809.8CALM1, CALM2
24positive regulation of protein serine/threonine kinase activityGO:00719029.8CALM1, CALM2
25nitric oxide metabolic processGO:00462099.7CALM1, CALM2
26regulation of nitric-oxide synthase activityGO:00509999.6CALM1, CALM2
27positive regulation of nitric-oxide synthase activityGO:00510009.6CALM1, CALM2
28response to amphetamineGO:00019759.5CALM1, CALM2
29regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionGO:00108819.5CALM1, CALM2
30regulation of heart rateGO:00020279.4CALM1, CALM2
31regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:00108809.2CALM1, CALM2
32carbohydrate metabolic processGO:00059758.3CALM1, CALM2, CSPG5, FUT2

Molecular functions related to Spontaneous Ocular Nystagmus according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1nitric-oxide synthase regulator activityGO:00302359.9CALM1, CALM2
2titin bindingGO:00314329.9CALM1, CALM2
3type 3 metabotropic glutamate receptor bindingGO:00318009.9CALM1, CALM2
4N-terminal myristoylation domain bindingGO:00319979.9CALM1, CALM2
5protein phosphatase activator activityGO:00725429.8CALM1, CALM2
6protein serine/threonine kinase activator activityGO:00435399.8CALM1, CALM2
7thioesterase bindingGO:00319969.8CALM1, CALM2
8adenylate cyclase bindingGO:00081799.8CALM1, CALM2
9calcium-dependent protein bindingGO:00483069.7CALM1, CALM2
10phosphatidylinositol 3-kinase bindingGO:00435489.6CALM1, CALM2
11nitric-oxide synthase bindingGO:00509989.5CALM1, CALM2
12phospholipase bindingGO:00432749.2CALM1, CALM2
13protein domain specific bindingGO:00199049.0CALM1, CALM2, MED12

Sources for Spontaneous Ocular Nystagmus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet