MCID: SPR010
MIFTS: 51

Sporotrichosis malady

Infectious diseases category

Summaries for Sporotrichosis

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Sources:
8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A primary systemic mycosis that results in a systemic fungal infection, has material basis in sporothrix schenckii in animals and humans and results in formation of red papule at the site of inoculation.

MalaCards: Sporotrichosis, also known as sporotrichosis, unspecified, is related to syphilis and hairy cell leukemia. An important gene associated with Sporotrichosis is BAG3 (BCL2-associated athanogene 3), and among its related pathways is Primary immunodeficiency. The drugs itraconazole and potassium iodide and the compounds fluconazole and sulfolipid i have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and lung.

CDC:3 The page you requested has been moved. Please update your links and bookmarks to the new Sporotrichosis web page.

Wikipedia:63 Sporotrichosis (also known as \"Rose gardener\'s disease\") is a disease caused by the infection of the... more...

Aliases & Classifications for Sporotrichosis

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 48Orphanet, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Characteristics (Orphanet epidemiological data):

48
sporotrichosis:
Inheritance: Sporadic; Prevalence: <1/1000000; Age of death: Normal


Aliases & Descriptions:

sporotrichosis 8 42 10 48 60
sporotrichosis, unspecified 8
rose gardener's disease 42
sporotrichosis nos 8


External Ids:

Disease Ontology8 DOID:14484
MeSH34 D013174
ICD9CM27 117.1
MESH via Orphanet35 D013174
ICD10 via Orphanet26 B42.0, B42.1, B42.7 B42.8, B42.9, more
SNOMED-CT via Orphanet57 42094007
UMLS via Orphanet61 C0038034
ICD1025 B42, B42.9

Related Diseases for Sporotrichosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Sporotrichosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 78)
idRelated DiseaseScoreTop Affiliating Genes
1syphilis30.0CD79A
2hairy cell leukemia30.0ITGAX
3candidiasis29.8CD79A, HTN3
4arthritis10.3
5chromoblastomycosis10.2
6pyoderma gangrenosum10.2
7meningitis10.2
8pyoderma10.2
9acquired immunodeficiency syndrome10.1
10laryngitis10.1
11leishmaniasis10.1
12tuberculosis10.1
13gout10.0
14rosacea10.0
15lymphangitis10.0
16lepromatous leprosy10.0
17secondary syphilis10.0
18blastomycosis10.0
19histoplasmosis10.0
20keratoacanthoma10.0
21leprosy10.0
22leukemia10.0
23osteomyelitis10.0
24sarcoidosis10.0
25sarcoma10.0
26polyclonal hypergammaglobulinemia10.0CD79A
27diphtheria10.0CD79A
28giardiasis10.0CD79A
29cryptosporidiosis10.0CD79A
30gastritis10.0CD79A
31meningoencephalitis10.0CD79A
32dermatitis herpetiformis10.0CD79A
33pemphigus foliaceus10.0CD79A
34q fever10.0CD79A
35brucellosis10.0CD79A
36mumps10.0CD79A
37pyelonephritis10.0CD79A
38macroglobulinemia10.0CD79A
39acute leukemia10.0ITGAX
40cd40 ligand deficiency10.0CD40LG
41guillain-barre syndrome10.0CD40LG
42leptospirosis10.0CD40LG
43herpes simplex10.0CD79A
44congenital toxoplasmosis10.0CD40LG, CD79A
45immunoglobulin g deficiency10.0CD40LG, CD79A
46selective iga deficiency disease10.0CD40LG, CD79A
47immunodeficiency, centromere instability and facial anomalies syndrome10.0CD79A, CD40LG
48immunoglobulin alpha deficiency10.0CD79A, CD40LG
49immunodeficiency with hyper igm type 110.0CD79A, CD40LG
50infectious mononucleosis10.0CD79A, CD40LG

Graphical network of the top 20 diseases related to Sporotrichosis:



Diseases related to sporotrichosis

Clinical Features for Sporotrichosis

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Drugs & Therapeutics for Sporotrichosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Sporotrichosis

Drug clinical trials:

Search ClinicalTrials for Sporotrichosis

Search NIH Clinical Center for Sporotrichosis

Search CenterWatch for Sporotrichosis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Sporotrichosis

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Anatomical Context for Sporotrichosis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Sporotrichosis:

32
Skin, Bone, Lung, Brain, Testes, Liver, Breast, Monocytes

Animal Models for Sporotrichosis or affiliated genes

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Publications for Sporotrichosis

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Sources:
50PubMed
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Articles related to Sporotrichosis:

(show top 50)    (show all 500)
idTitleAuthorsYear
1
Treatment abandonment in feline sporotrichosis - study of 147 cases. (22898261)
2013
2
Sporotrichosis of the face by autoinoculation in a patient undergoing tacrolimus treatment. (22168566)
2012
3
Epidemiological findings and laboratory evaluation of sporotrichosis: a description of 103 cases in cats and dogs in southern Brazil. (22143899)
2012
4
Sensitivity of cytopathological examination in the diagnosis of feline sporotrichosis. (21131220)
2011
5
Variation in genotype and higher virulence of a strain of Sporothrix schenckii causing disseminated cutaneous sporotrichosis. (21717135)
2011
6
Molluscum-like lesions in a patient with sporotrichosis. (22281918)
2011
7
Zoonotic Sporotrichosis in Rio de Janeiro, Brazil: a protracted epidemic yet to be curbed. (20064034)
2010
8
Sporotrichosis: an update. (20930700)
2010
9
Zoonotic sporotrichosis of lymphocutaneous type in a man acquired from a domesticated feline source: report of a first case in southern Karnataka, India. (20064175)
2009
10
Extracutaneous sporotrichosis in a patient with liver cirrhosis. (17592891)
2007
11
Localized cutaneous sporotrichosis in a child. (17043206)
2006
12
Usefulness of itraconazole for sporotrichosis in Japan: study of three cases and literature comparison of therapeutic effects before and after release on the market. (16436341)
2006
13
Fixed cutaneous sporotrichosis: an unusual diagnosis in West Europe. (16681620)
2006
14
Primary conjunctival sporotrichosis: two cases from a zoonotic epidemic in Rio de Janeiro, Brazil. (15829813)
2005
15
Sporotrichosis: a forgotten disease in the drug research agenda. (15482174)
2004
16
Pathology of sporotrichosis in 10 cats in Rio de Janeiro. (12622288)
2003
17
Cutaneous sporotrichosis: an unusual clinico-pathologic and therapeutic presentation. (14641627)
2003
18
Sporotrichosis. (14584741)
2003
19
Erythema nodosum associated with sporotrichosis. (11982651)
2002
20
A case of lymphocutaneous sporotrichosis]. (11479537)
2001
21
Disseminated cutaneous sporotrichosis: a marker of osteoarticular sporotrichosis masquerading as gout. (11737440)
2001
22
Itraconazole for treatment of sporotrichosis in a dog residing on a Christmas tree farm. (11345307)
2001
23
Case report. An unusual case of cutaneous sporotrichosis and its response to weekly fluconazole. (10838853)
2000
24
Photo Quiz. Diagnosis: needle prick-induced sporotrichosis. (10766498)
2000
25
Sporotrichosis infection on mines of the Witwatersrand. (10689229)
2000
26
Sporotrichosis in Peru: description of an area of hyperendemicity. (10619735)
2000
27
Epidemic cutaneous sporotrichosis: report of 16 cases in Queensland due to mouldy hay. (9529687)
1998
28
Disseminated sporotrichosis and Sporothrix schenckii fungemia as the initial presentation of human immunodeficiency virus infection. (9636870)
1998
29
Handyperson's hazard: crawl space sporotrichosis. (7474266)
1995
30
Scedosporium apiospermum infection imitating lymphocutaneous sporotrichosis in a patient with myeloblastic-monocytic leukaemia. (8555041)
1995
31
Borderline lepromatous leprosy masquerading as lymphocutaneous sporotrichosis. (7500826)
1995
32
Update on sporotrichosis. (7625942)
1995
33
Sporotrichosis in man and animal. (8002136)
1994
34
Symmetrical deforming cutaneous sporotrichosis of long duration. (1406788)
1992
35
A familial occurrence of sporotrichosis. (2365904)
1990
36
Sporotrichosis in the metropolitan area of Cusco, Peru, and in its region. (2266999)
1990
37
Sporothrix schenckii var luriei as the cause of sporotrichosis in Italy. (2670603)
1989
38
Sporotrichosis in association with Arbor Day activities. (3185628)
1988
39
Facial sporotrichosis in children. (3774649)
1986
40
Facial sporotrichosis in an infant. (6697770)
1984
41
Studies on sporotrichosis. Pathogenicity and morphogenesis in the Transvaal strains of Sporothrix schenckii. (6493317)
1984
42
Immune deficiency presenting as disseminated sporotrichosis. (6726496)
1984
43
Sporotrichosis among hay-mulching workers--Oklahoma, New Mexico. (6438470)
1984
44
Sporotrichosis in Wisconsin. (6858190)
1983
45
Feline sporotrichosis. Transmission to man. (7092255)
1982
46
Sporotrichosis of the abdomen. (7199418)
1982
47
Sporotrichosis associated with Wisconsin sphagnum moss. (6817054)
1982
48
Fixed cutaneous sporotrichosis of the face. Successful treatment of a case review of the literature. (7085959)
1982
49
Tropical fish aquariums. A source of Mycobacterium marinum infections resembling sporotrichosis. (5466918)
1970
50
Sporotrichosis: inoculation on the palpebral conjunctiva with descending nodular lymphangitis. (14810204)
1951

Genetic Variations for Sporotrichosis

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Expression for genes affiliated with Sporotrichosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Sporotrichosis

Search GEO for disease gene expression data for Sporotrichosis.

Pathways for genes affiliated with Sporotrichosis

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Sources:
29KEGG
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Pathways related to Sporotrichosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3CD79A, CD40LG

Compounds for genes affiliated with Sporotrichosis

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Sources:
44Novoseek, 11DrugBank, 28IUPHAR, 49PharmGKB, 24HMDB
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Compounds related to Sporotrichosis according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
1fluconazole44 1110.7CD79A, HTN3
2sulfolipid i449.7CD79A, CD40LG
3sandoglobulin449.7CD40LG, CD79A
4vancomycin44 1110.7CD79A, CD40LG
5pneumococcal449.7CD79A, CD40LG
6blys449.7CD79A, CD40LG
7tuberculin449.7CD40LG, CD79A
8praziquantel44 1110.7CD79A, CD40LG
9hemocyanin449.7CD79A, CD40LG
10gliadin449.7CD79A, CD40LG
11silicone449.7CD40LG, CD79A
12mannan449.7CD79A, CD40LG
13okt3449.6CD40LG, CD79A
14glutaraldehyde449.6CD79A, CD40LG
15sulfasalazine44 28 49 1112.6CD79A, CD40LG
16cardiolipin44 1110.6CD40LG, CD79A
17mycophenolate mofetil44 49 1111.6CD79A, CD40LG
18valproate449.6CD40LG, CD79A
19phenytoin44 49 28 1112.6CD79A, CD40LG
20cytidine44 11 2411.6CD79A, CD40LG
21ivig449.5CD79A, CD40LG
22doxycycline44 1110.5CD40LG, CD79A
23vitamin b12449.5CD79A, CD40LG
24neopterin449.4CD79A, CD40LG
25rituximab44 49 1111.3CD40LG, CD79A
26polyethylene glycol449.3CD79A, CD40LG
27pmma449.3CD79A, CD40LG, HTN3
28anti-fungal449.3CD79A, CD40LG, HTN3
29allergens449.2CD79A, CD40LG
30theophylline44 28 11 2412.0CD79A, CD40LG
31fibrinogen448.8CD79A, CD40LG, ITGAX
32heparin44 28 11 2411.6CD79A, CD40LG, ITGAX

GO Terms for genes affiliated with Sporotrichosis

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16Gene Ontology
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Cellular components related to Sporotrichosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.2CD79A, CD40LG, ITGAX
2plasma membraneGO:0058867.6CD79A, CD40LG, BAG3, ITGAX, KCNB1

Biological processes related to Sporotrichosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:0301839.3CD79A, CD40LG
2B cell proliferationGO:0421009.0CD79A, CD40LG

Products for genes affiliated with Sporotrichosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sporotrichosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet