MCID: SPR010
MIFTS: 51

Sporotrichosis malady

Infectious diseases category

Summaries for Sporotrichosis

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8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A primary systemic mycosis that results in a systemic fungal infection, has material basis in sporothrix schenckii in animals and humans and results in formation of red papule at the site of inoculation.

MalaCards: Sporotrichosis, also known as sporotrichosis, unspecified, is related to syphilis and hairy cell leukemia. An important gene associated with Sporotrichosis is BAG3 (BCL2-associated athanogene 3), and among its related pathways is Primary immunodeficiency. The drugs itraconazole and potassium iodide and the compounds fluconazole and sulfolipid i have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and lung.

CDC:3 The page you requested has been moved. Please update your links and bookmarks to the new Sporotrichosis web page.

Wikipedia:63 Sporotrichosis (also known as \"Rose gardener\'s disease\") is a disease caused by the infection of the... more...

Aliases & Classifications for Sporotrichosis

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 48Orphanet, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Characteristics (Orphanet epidemiological data):

48
sporotrichosis:
Inheritance: Sporadic; Prevalence: <1/1000000; Age of death: Normal


Aliases & Descriptions:

sporotrichosis 8 42 10 48 60
sporotrichosis, unspecified 8
rose gardener's disease 42
sporotrichosis nos 8


External Ids:

Disease Ontology8 DOID:14484
MeSH34 D013174
ICD9CM27 117.1
MESH via Orphanet35 D013174
ICD10 via Orphanet26 B42.0, B42.1, B42.7 B42.8, B42.9, more
SNOMED-CT via Orphanet57 42094007
UMLS via Orphanet61 C0038034
ICD1025 B42, B42.9

Related Diseases for Sporotrichosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Sporotrichosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 78)
idRelated DiseaseScoreTop Affiliating Genes
1syphilis30.0CD79A
2hairy cell leukemia30.0ITGAX
3candidiasis29.8CD79A, HTN3
4arthritis10.3
5chromoblastomycosis10.2
6pyoderma gangrenosum10.2
7meningitis10.2
8pyoderma10.2
9acquired immunodeficiency syndrome10.1
10laryngitis10.1
11leishmaniasis10.1
12tuberculosis10.1
13gout10.0
14rosacea10.0
15lymphangitis10.0
16lepromatous leprosy10.0
17secondary syphilis10.0
18blastomycosis10.0
19histoplasmosis10.0
20keratoacanthoma10.0
21leprosy10.0
22leukemia10.0
23osteomyelitis10.0
24sarcoidosis10.0
25sarcoma10.0
26polyclonal hypergammaglobulinemia10.0CD79A
27diphtheria10.0CD79A
28giardiasis10.0CD79A
29cryptosporidiosis10.0CD79A
30gastritis10.0CD79A
31meningoencephalitis10.0CD79A
32dermatitis herpetiformis10.0CD79A
33pemphigus foliaceus10.0CD79A
34q fever10.0CD79A
35brucellosis10.0CD79A
36mumps10.0CD79A
37pyelonephritis10.0CD79A
38macroglobulinemia10.0CD79A
39acute leukemia10.0ITGAX
40cd40 ligand deficiency10.0CD40LG
41guillain-barre syndrome10.0CD40LG
42leptospirosis10.0CD40LG
43herpes simplex10.0CD79A
44congenital toxoplasmosis10.0CD40LG, CD79A
45immunoglobulin g deficiency10.0CD40LG, CD79A
46selective iga deficiency disease10.0CD40LG, CD79A
47immunodeficiency, centromere instability and facial anomalies syndrome10.0CD79A, CD40LG
48immunoglobulin alpha deficiency10.0CD79A, CD40LG
49immunodeficiency with hyper igm type 110.0CD79A, CD40LG
50infectious mononucleosis10.0CD79A, CD40LG

Graphical network of the top 20 diseases related to Sporotrichosis:



Diseases related to sporotrichosis

Clinical Features for Sporotrichosis

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Drugs & Therapeutics for Sporotrichosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Sporotrichosis

Drug clinical trials:

Search ClinicalTrials for Sporotrichosis

Search NIH Clinical Center for Sporotrichosis

Search CenterWatch for Sporotrichosis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Sporotrichosis

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Anatomical Context for Sporotrichosis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Sporotrichosis:

32
Skin, Bone, Lung, Brain, Testes, Liver, Breast, Monocytes

Animal Models for Sporotrichosis or affiliated genes

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Publications for Sporotrichosis

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Sources:
50PubMed
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Articles related to Sporotrichosis:

(show top 50)    (show all 500)
idTitleAuthorsYear
1
Atypical presentation of sporotrichosis: report of three cases. (23563841)
2013
2
Therapeutic monoclonal antibody for sporotrichosis. (23226146)
2012
3
A case of disseminated sporotrichosis treated with prednisolone, immunosuppressants, and tocilizumab under the diagnosis of rheumatoid arthritis. (22864133)
2012
4
Disseminated sporotrichosis in a patient with a past history of lepromatous leprosy: a case report. (22074310)
2012
5
Cutaneous sporotrichosis: a six-year review of 19 cases in a tertiary referral center in Malaysia. (22607289)
2012
6
Sporotrichosis: clinical and histopathological manifestations. (21512340)
2011
7
Use of local hyperthermia to treat sporotrichosis in a cat. (20154314)
2010
8
Oral potassium iodide for the treatment of sporotrichosis. (19821356)
2009
9
Cutaneous sporotrichosis of face: polymorphism and reactivation after intralesional triamcinolone. (17558054)
2007
10
Sporotrichosis in an HIV-positive man with oral lesions: a case report. (17718145)
2007
11
Sporotrichosis in Iran. (17592890)
2007
12
Fatal sporotrichosis. (17121061)
2006
13
Canine sporotrichosis in Rio de Janeiro, Brazil: clinical presentation, laboratory diagnosis and therapeutic response in 44 cases (1998-2003). (16805098)
2006
14
Epidemiology of sporotrichosis: a study of 304 cases in Brazil. (15761423)
2005
15
Importance of the direct fresh examination in the diagnosis of cutaneous sporotrichosis. (15533061)
2004
16
Potassium iodide remains the most effective therapy for cutaneous sporotrichosis. (14660263)
2003
17
Localized lymphatic sporotrichosis after fish-induced injury (Tilapia sp.). (12230224)
2002
18
An unusual episode of lupus vulgaris masquerading as sporotrichosis. (11554997)
2001
19
Solitary sporotrichosis lasting for 10 years. (10026416)
1999
20
Cutaneous New World leishmaniasis-sporotrichosis coinfection: report of 3 cases. (10365936)
1999
21
Erysipeloid sporotrichosis in a woman with Cushing's disease. (10025762)
1999
22
Sporotrichosis. (10476718)
1999
23
False-positive antineutrophil cytoplasmic antibodies in a patient with cavitary pulmonary sporotrichosis. (9528726)
1998
24
Lymphangitic sporotrichosis: an uncommon bilateral localization. (9750337)
1998
25
Pulmonary sporotrichosis with hyphae in a human immunodeficiency virus-infected patient. A case report. (9100791)
1997
26
Sporotrichosis-like lesions caused by a Paecilomyces genus fungus. (7607802)
1995
27
Urinary sporotrichosis in a renal allograft recipient. (8015660)
1994
28
Efficacy of acute phase and maintenance therapy with itraconazole in an AIDS patient with sporotrichosis. (7805693)
1994
29
Zoonotic transmission of sporotrichosis: case report and review. (8095815)
1993
30
Tissue response in sporotrichosis: light and electron microscopy studies. (1406787)
1992
31
Concurrent infection with sporotrichosis and blastomycosis: an unusual case. (1935247)
1991
32
Feline-transmitted sporotrichosis in the southwestern United States. (1877193)
1991
33
Osseous sporotrichosis. (2600443)
1989
34
Sporotrichosis. (2771823)
1989
35
Multistate outbreak of sporotrichosis in seedling handlers, 1988. (2971870)
1988
36
Multifocal systemic sporotrichosis with lobar pulmonary involvement. (3065928)
1988
37
Cutaneous sporotrichosis. (2971782)
1988
38
Imaging rounds #95. Atypical infection: osteoarticular sporotrichosis. (3412796)
1988
39
Sporotrichosis. (3710673)
1986
40
Sporotrichosis. A historical approach. (3516899)
1986
41
Studies in sporotrichosis: fungal morphogenesis and pathogenicity in differing environments. (3796713)
1986
42
Feline sporotrichosis: a report of five cases with transmission to humans. (3722508)
1986
43
Primary pulmonary sporotrichosis. Report of eight cases with clinicopathologic review. (3993831)
1985
44
Systemic sporotrichosis with osteomyelitis. (6725377)
1984
45
Epidemiology and ecology of sporotrichosis in Japan. (6485628)
1984
46
Fungal elements in tissues of sporotrichosis. (6828078)
1983
47
Sporotrichosis treated with garlic juice. A case report. (6852881)
1983
48
Polymorphonuclear leukocyte chemotaxis in sporotrichosis. (7121561)
1982
49
Sporotrichosis due to contact with contaminated sphagnum moss. (7200390)
1982
50
A case for diagnosis (sporotrichosis? secondary syphilis, treated). (20240700)
1947

Genetic Variations for Sporotrichosis

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Expression for genes affiliated with Sporotrichosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Sporotrichosis

Search GEO for disease gene expression data for Sporotrichosis.

Pathways for genes affiliated with Sporotrichosis

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Sources:
29KEGG
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Pathways related to Sporotrichosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3CD79A, CD40LG

Compounds for genes affiliated with Sporotrichosis

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Sources:
44Novoseek, 11DrugBank, 28IUPHAR, 49PharmGKB, 24HMDB
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Compounds related to Sporotrichosis according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
1fluconazole44 1110.7CD79A, HTN3
2sulfolipid i449.7CD79A, CD40LG
3sandoglobulin449.7CD40LG, CD79A
4vancomycin44 1110.7CD79A, CD40LG
5pneumococcal449.7CD79A, CD40LG
6blys449.7CD79A, CD40LG
7tuberculin449.7CD40LG, CD79A
8praziquantel44 1110.7CD79A, CD40LG
9hemocyanin449.7CD79A, CD40LG
10gliadin449.7CD79A, CD40LG
11silicone449.7CD40LG, CD79A
12mannan449.7CD79A, CD40LG
13okt3449.6CD40LG, CD79A
14glutaraldehyde449.6CD79A, CD40LG
15sulfasalazine44 28 49 1112.6CD79A, CD40LG
16cardiolipin44 1110.6CD40LG, CD79A
17mycophenolate mofetil44 49 1111.6CD79A, CD40LG
18valproate449.6CD40LG, CD79A
19phenytoin44 49 28 1112.6CD79A, CD40LG
20cytidine44 11 2411.6CD79A, CD40LG
21ivig449.5CD79A, CD40LG
22doxycycline44 1110.5CD40LG, CD79A
23vitamin b12449.5CD79A, CD40LG
24neopterin449.4CD79A, CD40LG
25rituximab44 49 1111.3CD40LG, CD79A
26polyethylene glycol449.3CD79A, CD40LG
27pmma449.3CD79A, CD40LG, HTN3
28anti-fungal449.3CD79A, CD40LG, HTN3
29allergens449.2CD79A, CD40LG
30theophylline44 28 11 2412.0CD79A, CD40LG
31fibrinogen448.8CD79A, CD40LG, ITGAX
32heparin44 28 11 2411.6CD79A, CD40LG, ITGAX

GO Terms for genes affiliated with Sporotrichosis

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Sources:
16Gene Ontology
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Cellular components related to Sporotrichosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.2CD79A, CD40LG, ITGAX
2plasma membraneGO:0058867.6CD79A, CD40LG, BAG3, ITGAX, KCNB1

Biological processes related to Sporotrichosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:0301839.3CD79A, CD40LG
2B cell proliferationGO:0421009.0CD79A, CD40LG

Products for genes affiliated with Sporotrichosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sporotrichosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet