Squamous Cell Carcinoma, Head and Neck, Somatic malady

MalaCards: Squamous Cell Carcinoma, Head and Neck, Somatic, also known as squamous cell carcinoma, is related to oral squamous cell carcinoma and squamous cell carcinoma of the head and neck. An important gene associated with Squamous Cell Carcinoma, Head and Neck, Somatic is PTEN (phosphatase and tensin homolog). The drugs bleomycin and bleomycin sulfate have been mentioned in the context of this disorder.

OMIM: 275355

squamous cell carcinoma, head and neck, somatic 33 squamous cell carcinoma 43

Diseases related to squamous cell carcinoma, head and neck, somatic by text searches and GeneDecks gene sharing:

(show top 50)    (show all 215)

id	Related Disease	Score	Top Affiliating Genes
1	oral squamous cell carcinoma	15.2
2	squamous cell carcinoma of the head and neck	13.8
3	laryngitis	13.6
4	laryngeal squamous cell carcinoma	13.6
5	cervical squamous cell carcinoma	11.8
6	lung squamous cell carcinoma	11.7
7	hypoxia	11.4
8	keratoacanthoma	10.8
9	basaloid squamous cell carcinoma	10.5
10	retinoblastoma	10.2
11	lung cancer	10.1
12	skin squamous cell carcinoma	10.1
13	cervical cancer	10.0
14	hypercalcemia	10.0
15	cervical intraepithelial neoplasia	9.9
16	papilloma	9.9
17	basal cell carcinoma	9.9
18	leukoplakia	9.8
19	pharyngitis	9.6
20	adenoid squamous cell carcinoma	9.5
21	keratinizing squamous cell carcinoma	9.3
22	bladder squamous cell carcinoma	9.2
23	esophageal cancer	9.2
24	maxillary sinus squamous cell carcinoma	9.2
25	melanoma	9.0
26	oral cancer	9.0
27	sinusitis	9.0
28	oral leukoplakia	8.9
29	small cell carcinoma	8.9
30	teratoma	8.9
31	adenoiditis	8.9
32	anemia	8.9
33	cystic teratoma	8.9
34	esophagus squamous cell carcinoma	8.9
35	anal margin squamous cell carcinoma	8.7
36	breast squamous cell carcinoma	8.7
37	lichen sclerosus	8.7
38	lung adenocarcinoma	8.7
39	neuronitis	8.7
40	nasal cavity squamous cell carcinoma	8.7
41	penis squamous cell carcinoma	8.7
42	prostate squamous cell carcinoma	8.7
43	scrotum squamous cell carcinoma	8.7
44	verrucous carcinoma	8.7
45	cornea squamous cell carcinoma	8.4
46	vulva squamous cell carcinoma	8.4
47	endometrial squamous cell carcinoma	8.4
48	xeroderma pigmentosum	8.4
49	fallopian tube squamous cell carcinoma	8.4
50	gingivitis	8.4

Clinical features from OMIM: 275355

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 bleomycin, bleomycin sulfate

Genes related to squamous cell carcinoma, head and neck, somatic according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	PTEN	phosphatase and tensin homolog	11.0	Disorders