MCID: STL001
MIFTS: 43

St. Louis Encephalitis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for St. Louis Encephalitis

MalaCards integrated aliases for St. Louis Encephalitis:

Name: St. Louis Encephalitis 12 55 3 14
Encephalitis, St. Louis 41 69
Neuroinvasive St. Louis Encephalitis Virus Infection 12
Saint Louis Encephalitis 55

Characteristics:

Orphanet epidemiological data:

55
st. louis encephalitis
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:



External Ids:

Disease Ontology 12 DOID:10845
ICD10 32 A83.3
ICD9CM 34 062.3
MeSH 41 D004674
Orphanet 55 ORPHA83484
MESH via Orphanet 42 D004674
UMLS via Orphanet 70 C0014060
ICD10 via Orphanet 33 A83.3
UMLS 69 C0014060

Summaries for St. Louis Encephalitis

Disease Ontology : 12 A viral infectious disease that results_in inflammation located in brain, has material basis in St. Louis encephalitis virus, which is transmitted_by Culex mosquitoes. The infection has symptom headache, has symptom high fever, has symptom neck stiffness, has symptom stupor, has symptom disorientation, has symptom coma, has symptom tremors, has symptom convulsions and has symptom spastic paralysis.

MalaCards based summary : St. Louis Encephalitis, also known as encephalitis, st. louis, is related to murray valley encephalitis and encephalitis, and has symptoms including headache, high fever and neck stiffness. An important gene associated with St. Louis Encephalitis is C21orf2 (Chromosome 21 Open Reading Frame 2), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and PI3K-Akt signaling pathway. Affiliated tissues include brain, brain and testes.

Related Diseases for St. Louis Encephalitis

Diseases related to St. Louis Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 murray valley encephalitis 29.1 ERVW-1 KRAS RAF1 SNORA73B
2 encephalitis 11.3
3 west nile virus 10.6
4 yellow fever 10.3
5 aging 10.3
6 dengue virus 10.3
7 eastern equine encephalitis 10.3
8 shipyard eye 10.3
9 keratoconjunctivitis 10.3
10 poliomyelitis 10.2
11 respiratory system benign neoplasm 10.2 KRAS RAF1
12 blood group, i system 10.1
13 louping ill 10.1
14 western equine encephalitis 10.1
15 rabies 10.1
16 cerebritis 10.1
17 venezuelan equine encephalitis 10.1
18 stomatitis 10.1
19 pulmonic stenosis 10.1 KRAS RAF1
20 adenosquamous pancreas carcinoma 10.0 IFNA2 KRAS
21 phlebotomus fever 10.0 ERVW-1 IFNA2
22 lung benign neoplasm 10.0 KRAS RAF1
23 malaria 10.0
24 cataract 10.0
25 dengue disease 10.0
26 chikungunya 10.0
27 tick-borne encephalitis 10.0
28 japanese encephalitis 10.0
29 allergic hypersensitivity disease 10.0
30 vascular disease 10.0
31 vaccinia 10.0
32 polyradiculopathy 10.0
33 subacute thyroiditis 10.0
34 thyroiditis 10.0
35 neuronitis 10.0
36 influenza 10.0
37 intrauterine infections 10.0
38 common cold 9.8 IFNA2 RNASE3

Graphical network of the top 20 diseases related to St. Louis Encephalitis:



Diseases related to St. Louis Encephalitis

Symptoms & Phenotypes for St. Louis Encephalitis

Symptoms:

12
  • headache
  • high fever
  • neck stiffness
  • stupor
  • disorientation
  • coma
  • tremors
  • convulsions
  • spastic paralysis

Drugs & Therapeutics for St. Louis Encephalitis

Search Clinical Trials , NIH Clinical Center for St. Louis Encephalitis

Cochrane evidence based reviews: encephalitis, st. louis

Genetic Tests for St. Louis Encephalitis

Anatomical Context for St. Louis Encephalitis

The Foundational Model of Anatomy Ontology organs/tissues related to St. Louis Encephalitis:

18
Brain

MalaCards organs/tissues related to St. Louis Encephalitis:

38
Brain, Testes, Kidney, Pituitary, Thyroid, Salivary Gland

Publications for St. Louis Encephalitis

Articles related to St. Louis Encephalitis:

(show top 50) (show all 416)
# Title Authors Year
1
West Nile and St. Louis encephalitis viral genetic determinants of avian host competence. ( 29447156 )
2018
2
Toxicity of ar-curcumene and epi-I^-bisabolol from Hedychium larsenii (Zingiberaceae) essential oil on malaria, chikungunya and St. Louis encephalitis mosquito vectors. ( 27918946 )
2017
3
Mutagen resistance and mutation restriction of St. Louis encephalitis virus. ( 28284278 )
2017
4
Diagnosis of Fatal Human Case of St. Louis Encephalitis Virus Infection by Metagenomic Sequencing, California, 2016. ( 28930022 )
2017
5
St. Louis encephalitis virus possibly transmitted through blood transfusion-Arizona, 2015. ( 28905395 )
2017
6
Neuroinvasive St. Louis Encephalitis Virus Infection in Solid Organ Transplant Recipients. ( 28452107 )
2017
7
Reemergence of St. Louis Encephalitis Virus, California, 2015. ( 27869600 )
2016
8
Mutagen resistance and mutation restriction of St. Louis encephalitis virus. ( 27959789 )
2016
9
Surveillance for Western Equine Encephalitis, St. Louis Encephalitis, and West Nile Viruses Using Reverse Transcription Loop-Mediated Isothermal Amplification. ( 26807734 )
2016
10
Astrocyte response to St. Louis encephalitis virus. ( 26975980 )
2016
11
Activity Patterns of St. Louis Encephalitis and West Nile Viruses in Free Ranging Birds during a Human Encephalitis Outbreak in Argentina. ( 27564679 )
2016
12
Widespread Detection of Antibodies to Eastern Equine Encephalitis, West Nile, St. Louis Encephalitis, and Turlock Viruses in Various Species of Wild Birds from Across the United States. ( 27162269 )
2016
13
St. Louis Encephalitis virus mosquito vectors dynamics in three different environments in relation to remotely sensed environmental conditions. ( 25792419 )
2015
14
Concurrent Outbreaks of St. Louis Encephalitis Virus and West Nile Virus Disease - Arizona, 2015. ( 26656306 )
2015
15
First genome sequence of St. Louis encephalitis virus (SLEV) isolated from a human in Brazil. ( 25740285 )
2015
16
Exploring Genomic, Geographic and Virulence Interactions among Epidemic and Non-Epidemic St. Louis Encephalitis Virus (Flavivirus) Strains. ( 26312485 )
2015
17
Multiplex qRT-PCR for the Detection of Western Equine Encephalomyelitis, St. Louis Encephalitis, and West Nile Viral RNA in Mosquito Pools (Diptera: Culicidae). ( 26334826 )
2015
18
Consequences of in vitro host shift for St. Louis encephalitis virus. ( 24643879 )
2014
19
West Nile and St. Louis Encephalitis Viruses Antibodies Surveillance in Captive and Free-Ranging Birds of Prey from Argentina. ( 25106849 )
2014
20
Genetic Determinants of Differential Oral Infection Phenotypes of West Nile and St. Louis Encephalitis Viruses in Culex spp. Mosquitoes. ( 25157120 )
2014
21
West Nile and St. Louis encephalitis viruses. ( 25015498 )
2014
22
St. Louis encephalitis virus infection in woman, Peru. ( 24655897 )
2014
23
Transmission of endemic St Louis encephalitis virus strains by local Culex quinquefasciatus populations in Cordoba, Argentina. ( 23474474 )
2013
24
Seroprevalence of St. Louis encephalitis virus and West Nile virus (Flavivirus, Flaviviridae) in horses, Uruguay. ( 24490165 )
2013
25
Provenance and geographic spread of St. Louis encephalitis virus. ( 23760463 )
2013
26
Structure of the St. Louis encephalitis virus postfusion envelope trimer. ( 23115296 )
2013
27
Structural gene (prME) chimeras of St Louis encephalitis virus and West Nile virus exhibit altered in vitro cytopathic and growth phenotypes. ( 21940408 )
2012
28
Silent circulation of St. Louis encephalitis virus prior to an encephalitis outbreak in Cordoba, Argentina (2005). ( 22303490 )
2012
29
Serological detection of St. Louis encephalitis virus and West Nile virus in equines from Santa Fe, Argentina. ( 22666870 )
2012
30
Molecular evidence of St. Louis encephalitis virus infection in patients in Buenos Aires, Argentina. ( 22608840 )
2012
31
Effects of virus dose and extrinsic incubation temperature on vector competence of Culex nigripalpus (Diptera: Culicidae) for St. Louis encephalitis virus. ( 23270182 )
2012
32
Immunoglobulin G subclasses in antibody responses to St. Louis encephalitis virus infections. ( 21688106 )
2011
33
Seroconversion for West Nile and St. Louis encephalitis viruses among sentinel horses in Colombia. ( 22241119 )
2011
34
Evaluation of widely used diagnostic tests to detect West Nile virus infections in horses previously infected with St. Louis encephalitis virus or dengue virus type 2. ( 21346058 )
2011
35
Temporal and spatial alterations in mutant swarm size of St. Louis encephalitis virus in mosquito hosts. ( 21215334 )
2011
36
High throughput quantitative colorimetric microneutralization assay for the confirmation and differentiation of West Nile Virus and St. Louis encephalitis virus. ( 20207881 )
2010
37
Mosquito fauna inhabiting water bodies in the urban environment of CA^rdoba city, Argentina, following a St. Louis encephalitis outbreak. ( 21175948 )
2010
38
Vertical transmission of St. Louis encephalitis virus in Culex quinquefasciatus (Diptera: Culicidae) in CA^rdoba, Argentina. ( 20426683 )
2010
39
Severe winter freezes enhance St. Louis encephalitis virus amplification and epidemic transmission in peninsular Florida. ( 19960704 )
2009
40
Isolation of genotype V St. Louis encephalitis virus in Florida. ( 19331744 )
2009
41
Experimental passage of St. Louis encephalitis virus in vivo in mosquitoes and chickens reveals evolutionarily significant virus characteristics. ( 19924238 )
2009
42
Effect of sequential exposure on infection and dissemination rates for West Nile and St. Louis encephalitis viruses in Culex quinquefasciatus. ( 19492941 )
2009
43
Comparative thermostability of West Nile, St. Louis encephalitis, and western equine encephalomyelitis viruses during heat inactivation for serologic diagnostics. ( 19407138 )
2009
44
Evolution and dispersal of St. Louis encephalitis virus in the Americas. ( 18708161 )
2009
45
A duplex real-time reverse transcriptase polymerase chain reaction assay for the detection of St. Louis encephalitis and eastern equine encephalitis viruses. ( 18715737 )
2008
46
Eared dove (Zenaida auriculata, Columbidae) as host for St. Louis encephalitis virus (Flaviviridae, Flavivirus). ( 18429694 )
2008
47
Serologic diagnosis of West Nile and St. Louis encephalitis virus infections in domestic chickens. ( 18337340 )
2008
48
Reliable detection of St. Louis encephalitis virus by RT-nested PCR. ( 18208760 )
2008
49
Evaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeys. ( 18586359 )
2008
50
Genetic variation of St. Louis encephalitis virus. ( 18632961 )
2008

Variations for St. Louis Encephalitis

Expression for St. Louis Encephalitis

Search GEO for disease gene expression data for St. Louis Encephalitis.

Pathways for St. Louis Encephalitis

Pathways related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.66 IFNA2 IFNA8 KRAS RAF1
2
Show member pathways
12.65 IFNA2 IFNA8 KRAS RAF1
3 12.46 IFNA2 IFNA8 KRAS RAF1
4
Show member pathways
12.36 IFNA2 IFNA8 NXT1 RAF1
5
Show member pathways
12.08 IFNA2 IFNA8 KRAS RAF1
6
Show member pathways
12.03 IFNA2 IFNA8 RAF1
7
Show member pathways
11.94 IFNA2 IFNA8 KRAS RAF1
8 11.89 IFNA2 IFNA8 RAF1
9 11.25 KRAS RAF1
10 11.18 IFNA2 IFNA8
11 11.17 KRAS RAF1
12 11.17 IFNA2 IFNA8 KRAS RAF1
13 11.04 IFNA2 IFNA8 KRAS RAF1
14 10.99 KRAS RAF1
15 10.93 KRAS RAF1
16 10.75 KRAS RAF1
17 10.62 KRAS RAF1

GO Terms for St. Louis Encephalitis

Biological processes related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to virus GO:0051607 9.5 IFNA2 IFNA8 RNASE1
2 RNA phosphodiester bond hydrolysis GO:0090501 9.46 RNASE1 RNASE3
3 response to exogenous dsRNA GO:0043330 9.43 IFNA2 IFNA8
4 B cell proliferation GO:0042100 9.4 IFNA2 IFNA8
5 regulation of type I interferon-mediated signaling pathway GO:0060338 9.37 IFNA2 IFNA8
6 T cell activation involved in immune response GO:0002286 9.26 IFNA2 IFNA8
7 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.16 IFNA2 IFNA8
8 cytokine-mediated signaling pathway GO:0019221 9.13 IFNA2 IFNA8 KRAS
9 natural killer cell activation involved in immune response GO:0002323 8.62 IFNA2 IFNA8

Molecular functions related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ribonuclease activity GO:0004540 9.16 RNASE1 RNASE3
2 cytokine receptor binding GO:0005126 8.96 IFNA2 IFNA8
3 type I interferon receptor binding GO:0005132 8.62 IFNA2 IFNA8

Sources for St. Louis Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....