MCID: STC004
MIFTS: 35

Stachybotrys Chartarum malady

Category: Rare diseases

Aliases & Classifications for Stachybotrys Chartarum

About this section

Aliases & Descriptions for Stachybotrys Chartarum:

Name: Stachybotrys Chartarum 45
 
Stachybotrys Atra 45

Classifications:



Summaries for Stachybotrys Chartarum

About this section
Wikipedia:68 Stachybotrys chartarum, also called Stachybotrys atra, Stachybotrys alternans or Stilbospora chartarum,... more...

MalaCards based summary: Stachybotrys Chartarum, also known as stachybotrys atra, is related to asthma and hemosiderosis. An important gene associated with Stachybotrys Chartarum is CSF1 (Colony Stimulating Factor 1), and among its related pathways are Hypertrophy Model and LDL Oxidation in Atherogenesis. Affiliated tissues include lung, liver and thyroid, and related mouse phenotypes are integument and cardiovascular system.

Related Diseases for Stachybotrys Chartarum

About this section

Diseases related to Stachybotrys Chartarum via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
idRelated DiseaseScoreTop Affiliating Genes
1asthma28.9IL18, IL1A, IL1B, IL3
2hemosiderosis10.3
3neuronitis10.3
4orbital plasma cell granuloma10.2CCL7, IL3
5barbiturate dependence10.2CSF1, LIF
6pulmonary hemosiderosis10.2
7sick building syndrome10.2
8rhinitis10.2
9allergic asthma10.2
10cinca syndrome10.0IL18, IL1B
11ureteral disease10.0IL18, IL1B
12anatomical narrow angle borderline glaucoma10.0IL1A, IL1B
13lujo hemorrhagic fever10.0IL1A, IL1B
14glioblastoma multiforme10.0IL1A, IL1B
15dentin caries10.0IL18, IL1B
16optic neuritis10.0IL1A, IL1B
17meningoencephalocele10.0IL1A, IL1B
18placental abruption10.0IL18, IL1B
19peripheral retinal degeneration9.9IL1A, IL1B
20idiopathic spinal cord herniation9.9IL1A, IL1B
21foster-kennedy syndrome9.9IL1A, IL1B
22diversion colitis9.9IL18, IL1B
23testicular brenner tumor9.9IL1A, IL1B
24abdominal tuberculosis9.9IL1A, IL1B
25submandibular gland disease9.9IL1A, IL1B
26periodontal disease9.9IL1A, IL1B
27intervertebral disc disease9.8IL1A, IL1B
28hypoglycemic coma9.8IL18, IL1B
29funisitis9.8IL1A, IL1B
30granulomatous orchitis9.8IL1A, IL1B
31methylmalonic acidemia9.7IL1A, IL1B
32liver lipoma9.7IL1A, IL1B
33carotid artery disease9.7CSF1, IL1B
34mixed mineral dust pneumoconiosis9.7IL1A, IL1B
35single ventricular heart9.6IL18, IL1A, IL1B
36diamond-blackfan anemia 39.6IL18, IL1A, IL1B
37foveal hypoplasia 19.5CXCL2, IL1B
38glycoproteinosis9.5IL1A, IL1B
39hypocalciuric hypercalcemia, type i9.5IL18, IL1B, IL3
40long bone adamantinoma9.3IL1A, IL1B
41asphyxia neonatorum9.3CSF1, IL18, IL1A, IL1B
42rheumatoid arthritis9.3CSF1, IL18, IL1A, IL1B
43stalker chitayat syndrome7.3CCL7, CSF1, CXCL2, IL18, IL1A, IL1B

Graphical network of the top 20 diseases related to Stachybotrys Chartarum:



Diseases related to stachybotrys chartarum

Symptoms for Stachybotrys Chartarum

About this section

Drugs & Therapeutics for Stachybotrys Chartarum

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Stachybotrys Chartarum

Genetic Tests for Stachybotrys Chartarum

About this section

Anatomical Context for Stachybotrys Chartarum

About this section

MalaCards organs/tissues related to Stachybotrys Chartarum:

33
Lung, Liver, Thyroid, Endothelial, Bone, Spinal cord, B cells

Animal Models for Stachybotrys Chartarum or affiliated genes

About this section

MGI Mouse Phenotypes related to Stachybotrys Chartarum:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.0CSF1, IL18, IL1A, IL1B, LIF
2MP:00053857.0CSF1, CXCL2, IL18, IL1A, IL1B, LIF

Publications for Stachybotrys Chartarum

About this section

Articles related to Stachybotrys Chartarum:

(show top 50)    (show all 127)
idTitleAuthorsYear
1
Biological responses of Raw 264.7 macrophage exposed to two strains of Stachybotrys chartarum spores grown on four different wallboard types. (27097835)
2016
2
Repeated Mouse Lung Exposures to Stachybotrys chartarum Shift Immune Response From Type 1 to Type 2. (27148627)
2016
3
MALDI-TOF mass spectrometry fingerprinting: A diagnostic tool to differentiate dematiaceous fungi Stachybotrys chartarum and Stachybotrys chlorohalonata. (26036596)
2015
4
Chartarlactams A-P, Phenylspirodrimanes from the Sponge-Associated Fungus Stachybotrys chartarum with Antihyperlipidemic Activities. (24387683)
2014
5
Study on fungi in archives of offices, with a particular focus on Stachybotrys chartarum. (24139181)
2013
6
Satratoxin-G from the black mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys. (22552393)
2012
7
Allergen of the month--Stachybotrys chartarum. (22626607)
2012
8
Stachybotrys chartarum-induced hypersensitivity pneumonitis is TLR9 dependent. (21982832)
2011
9
Symptoms after mould exposure including Stachybotrys chartarum, and comparison with darkroom disease. (19796210)
2010
10
Purification and comparative neurotoxicity of the trichothecenes satratoxin G and roridin L2 from Stachybotrys chartarum. (20077192)
2009
11
Inflammatory and haematotoxic potential of indoor Stachybotrys chartarum (Ehrenb.) Hughes metabolites. (20061240)
2009
12
Stachybotrys chartarum, trichothecene mycotoxins, and damp building-related illness: new insights into a public health enigma. (18007011)
2008
13
Biomechanics of conidial dispersal in the toxic mold Stachybotrys chartarum. (17267247)
2007
14
Global gene expression changes underlying Stachybotrys chartarum toxin-induced apoptosis in murine alveolar macrophages: evidence of multiple signal transduction pathways. (17186382)
2007
15
Acute pulmonary hemorrhage during isoflurane anesthesia in two cats exposed to toxic black mold (Stachybotrys chartarum). (17764432)
2007
16
Pulmonary cytotoxicity of secondary metabolites of Stachybotrys chartarum (Ehrenb.) Hughes. (17195998)
2006
17
The development of species-specific immunodiagnostics for Stachybotrys chartarum: the role of cross-reactivity. (16436280)
2006
18
DNA damage, redox changes, and associated stress-inducible signaling events underlying the apoptosis and cytotoxicity in murine alveolar macrophage cell line MH-S by methanol-extracted Stachybotrys chartarum toxins. (16476459)
2006
19
Intranasal exposure to Stachybotrys chartarum enhances airway inflammation in allergic mice. (16322647)
2006
20
Comparison of inflammatory responses in mouse lungs exposed to atranones A and C from Stachybotrys chartarum. (16754538)
2006
21
Interactions between Streptomyces californicus and Stachybotrys chartarum can induce apoptosis and cell cycle arrest in mouse RAW264.7 macrophages. (15667833)
2005
22
Acute inflammatory responses to Stachybotrys chartarum in the lungs of infant rats: time course and possible mechanisms. (15647601)
2005
23
Ultraviolet germicidal irradiation disinfection of Stachybotrys chartarum. (16391660)
2005
24
Antibodies against Stachybotrys chartarum extract and its antigenic components, Stachyhemolysin and Stachyrase-A: a new clinical biomarker. (15874884)
2005
25
Comparison of immunomodulator mRNA and protein expression in the lungs of Stachybotrys chartarum spore-exposed mice. (16020192)
2005
26
Attributes of Stachybotrys chartarum and its association with human disease. (14767429)
2004
27
Wall relative humidity: a simple and reliable index for predicting Stachybotrys chartarum infestation in dwellings. (15104787)
2004
28
Protein translation inhibition by Stachybotrys chartarum conidia with and without the mycotoxin containing polysaccharide matrix. (15487326)
2004
29
Immunochemical Assay for Satratoxin G and other Macrocyclic Trichothecenes Associated with Indoor Air Contamination by Stachybotrys chartarum. (20021149)
2003
30
Molecular and phenotypic descriptions of Stachybotrys chlorohalonata sp. nov. and two chemotypes of Stachybotrys chartarum found in water-damaged buildings. (21149024)
2003
31
Effect of plasterboard composition on Stachybotrys chartarum growth and biological activity of spores. (12839740)
2003
32
Cryptic species in Stachybotrys chartarum. (21156555)
2002
33
Isolation and properties of stachyrase A, a chymotrypsin-like serine proteinase from Stachybotrys chartarum. (11748212)
2002
34
IgE-reactive proteins from Stachybotrys chartarum. (12141716)
2002
35
Stachylysin may be a cause of hemorrhaging in humans exposed to Stachybotrys chartarum. (11895972)
2002
36
Preliminary description of antigenic components characteristic of Stachybotrys chartarum. (11237513)
2001
37
Specific detection of Stachybotrys chartarum in pure culture using quantitative polymerase chain reaction. (11352593)
2001
38
Analysis of pulmonary surfactant by Fourier-transform infrared spectroscopy following exposure to Stachybotrys chartarum (atra) spores. (11245829)
2001
39
Stachybotrys chartarum: current knowledge of its role in disease. (11104457)
2000
40
The time course of responses to intratracheally instilled toxic Stachybotrys chartarum spores in rats. (11227851)
2000
41
Reduction of pulmonary toxicity of Stachybotrys chartarum spores by methanol extraction of mycotoxins. (10877773)
2000
42
Atranones A-G, from the toxigenic mold Stachybotrys chartarum. (11130678)
2000
43
Evaluation of Stachybotrys chartarum in the house of an infant with pulmonary hemorrhage: quantitative assessment before, during, and after remediation. (10741843)
2000
44
Quantification of siderophore and hemolysin from Stachybotrys chartarum strains, including a strain isolated from the lung of a child with pulmonary hemorrhage and hemosiderosis. (10831457)
2000
45
Volatile sesquiterpenes from Stachybotrys chartarum: Indicators for trichothecene producing mold species? (19009424)
2000
46
Sanitation of wallboard colonized with Stachybotrys chartarum. (10387112)
1999
47
Respiratory effects in mice exposed to airborne emissions from Stachybotrys chartarum and implications for risk assessment. (9783329)
1998
48
Health and immunology study following exposure to toxigenic fungi (Stachybotrys chartarum) in a water-damaged office environment. (8738349)
1996
49
Some cultural conditions that control production of verrucarin J, a cytotoxic metabolite of Stachybotrys chartarum. (7202311)
1982
50
Discovery of toxicogenic Stachybotrys chartarum strains in Finland. (5013039)
1972

Variations for Stachybotrys Chartarum

About this section

Expression for genes affiliated with Stachybotrys Chartarum

About this section
Search GEO for disease gene expression data for Stachybotrys Chartarum.

Pathways for genes affiliated with Stachybotrys Chartarum

About this section

Pathways related to Stachybotrys Chartarum according to GeneCards Suite gene sharing:

(show all 28)
idSuper pathwaysScoreTop Affiliating Genes
19.6IL18, IL1A
29.3CSF1, IL1B
39.2IL18, IL1B
49.2IL18, IL1B
59.2IL18, IL1B
69.2IL1A, IL1B
79.2IL1A, IL1B
89.2IL1A, IL1B
98.9CSF1, IL18, IL1B
108.9CSF1, IL1A, IL1B
118.8IL18, IL1A, IL1B
128.8IL18, IL1A, IL1B
13
Show member pathways
8.7CXCL2, IL18, IL1B
148.7CXCL2, IL18, IL1B
158.7IL1A, IL1B, IL3
168.7CXCL2, IL1A, IL1B
178.4CSF1, IL18, IL1A, IL1B
188.3CSF1, IL1A, IL1B, IL3
198.3CSF1, CXCL2, IL1A, IL1B
20
Show member pathways
8.3IL18, IL1A, IL1B, IL3
21
Show member pathways
8.3IL18, IL1A, IL1B, IL3
22
Show member pathways
8.3CXCL2, IL18, IL1A, IL1B
238.2CSF1, CXCL2, IL1B, LIF
24
Show member pathways
7.9CCL7, IL18, IL1A, IL1B, IL3
25
Show member pathways
6.4CCL7, CSF1, CXCL2, IL18, IL1A, IL1B
26
Show member pathways
6.4CCL7, CSF1, CXCL2, IL18, IL1A, IL1B
27
Show member pathways
6.4CCL7, CSF1, CXCL2, IL18, IL1A, IL1B
28
Show member pathways
6.4CCL7, CSF1, CXCL2, IL18, IL1A, IL1B

GO Terms for genes affiliated with Stachybotrys Chartarum

About this section

Biological processes related to Stachybotrys Chartarum according to GeneCards Suite gene sharing:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of macrophage differentiationGO:004565110.1CSF1, LIF
2positive regulation of inflammatory responseGO:005072910.0CCL7, IL18
3fever generationGO:00016609.8IL1A, IL1B
4extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.8IL1A, IL1B
5positive regulation of interleukin-2 biosynthetic processGO:00450869.8IL1A, IL1B
6negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.7IL1A, IL1B
7positive regulation of granulocyte macrophage colony-stimulating factor productionGO:00327259.7IL18, IL1B
8positive regulation of mitotic nuclear divisionGO:00458409.7IL1A, IL1B
9response to gamma radiationGO:00103329.7CCL7, IL1B
10positive regulation of vascular endothelial growth factor productionGO:00105759.7IL1A, IL1B
11positive regulation of interferon-gamma productionGO:00327299.7IL18, IL1B
12positive regulation of JNK cascadeGO:00463309.6IL1A, IL1B
13chemotaxisGO:00069359.6CCL7, CXCL2
14positive regulation of neutrophil chemotaxisGO:00900239.5CXCL2, IL1B
15embryo implantationGO:00075669.5IL1B, LIF
16lipopolysaccharide-mediated signaling pathwayGO:00316639.5IL18, IL1B
17positive regulation of astrocyte differentiationGO:00487119.4IL1B, LIF
18cytokine-mediated signaling pathwayGO:00192219.1IL1A, IL1B, IL3
19inflammatory responseGO:00069548.9IL18, IL1A, IL1B
20MAPK cascadeGO:00001658.9IL18, IL1B, IL3
21positive regulation of gene expressionGO:00106288.2IL18, IL1A, IL1B, LIF
22immune responseGO:00069556.6CCL7, CXCL2, IL18, IL1A, IL1B, IL3

Sources for Stachybotrys Chartarum

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet