MCID: STP004
MIFTS: 41

Staphylococcal Toxic Shock Syndrome malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Staphylococcal Toxic Shock Syndrome

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Sources:
31ICD10 via Orphanet, 48NIH Rare Diseases, 54Orphanet, 68UMLS
See all MalaCards sources

Aliases & Descriptions for Staphylococcal Toxic Shock Syndrome:

Name: Staphylococcal Toxic Shock Syndrome 48 68
Bacterial Toxic-Shock Syndrome 48 54
Staphylococcal Toxic-Shock Syndrome 54
 
Staphylococcal Tss 54
Bacterial Tss 54

Characteristics:

Orphanet epidemiological data:

54
staphylococcal toxic-shock syndrome:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (United States)
bacterial toxic-shock syndrome:
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

ICD10 via Orphanet31 A48.3

Summaries for Staphylococcal Toxic Shock Syndrome

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MalaCards based summary: Staphylococcal Toxic Shock Syndrome, also known as bacterial toxic-shock syndrome, is related to toxic shock syndrome and staphylococcal scarlet fever. An important gene associated with Staphylococcal Toxic Shock Syndrome is TNF (Tumor Necrosis Factor), and among its related pathways are amb2 Integrin signaling and Cellular Transformation by HTLV1. Affiliated tissues include t cells, monocytes and b cells.

Related Diseases for Staphylococcal Toxic Shock Syndrome

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Diseases related to Staphylococcal Toxic Shock Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 179)
idRelated DiseaseScoreTop Affiliating Genes
1toxic shock syndrome11.6
2staphylococcal scarlet fever11.5
3angiomatosis, diffuse corticomeningeal, of divry and van bogaert10.2HMGB1, TNF
4madras motor neuron disease10.2HMGB1, TNF
5choanal atresia, bilateral10.2CIITA, TNF
6autosomal dominant deafness-onychodystrophy syndrome10.2IFNG, TNF
7distal trisomy 14q10.2IFNG, TNF
8severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive10.2IFNG, TNF
9aniseikonia10.2IFNG, TNF
10urethral intrinsic sphincter deficiency10.2IFNG, TNF
11plantar wart10.2IFNG, TNF
12esophagus lymphoma10.2IFNG, TNF
13clostridium difficile colitis10.2IFNG, TNF
14parametritis10.2IFNG, TNF
15hypotrichosis 410.2IFNG, TNF
16osteodysplasty precocious of danks mayne and kozlowski10.2IFNG, TNF
17spastic paraplegia 110.2IFNG, TNF
18myeloid and lymphoid neoplasms with eosinophilia and abnormalities of pdgfra, pdgfrb, and fgfr110.2IFNG, TNF
19cyclosporiasis10.2IFNG, TNF
20neurotic disorder10.1IFNG, TNF
21venezuelan hemorrhagic fever10.1IFNG, TNF
22glucose intolerance10.1IFNG, TNF
23conduct disorder10.1IFNG, TNF
24pancreatic signet ring cell adenocarcinoma10.1IFNG, TNF
25pulpitis10.1IFNG, TNF
26tularemia10.1IFNG, TNF
27hypertropia10.1IFNG, TNF
28oral cavity cancer10.1IFNG, TNF
29hereditary alpha tryptasemia syndrome10.1IFNG, TNF
30hepatitis10.1IFNG, TNF
31acute myeloid leukemia with recurrent genetic anomaly10.1IFNG, TNF
32erb-duchenne and dejerine-klumpke palsies10.1IFNG, TNF
33microcephaly10.1IFNG, TNF
34benign deep fibrous histiocytoma10.1IFNG, TNF
35multiple epiphyseal dysplasia due to collagen 9 anomaly10.1IFNG, IGHE
36abnormal retinal correspondence10.1IFNG, TNF
37myofibroma10.1IFNG, IGHE
38red cell phospholipid defect with hemolysis10.1IFNG, TNF
39strawberry gallbladder10.1IFNG, TNF
40plummer's disease10.1IFNG, TNF
41isolated klippel-feil syndrome10.1IFNG, IGHE
42intussusception10.1IL1B, TNF
43hyperinsulinism due to glutamodehydrogenase deficiency10.1IFNG, IGHE
44orbital osteomyelitis10.1IFNG, TNF
45tau syndrome10.1IL1B, TNF
46central nervous system origin vertigo10.1IFNG, IGHE
47hypotrichosis-lymphedema-telangiectasia-renal defect syndrome10.1IL1B, TNF
48twin-to-twin transfusion syndrome10.1IL1B, TNF
49warthin tumor10.1IL1B, TNF
50pericholangitis10.1HMGB1, TNF

Graphical network of the top 20 diseases related to Staphylococcal Toxic Shock Syndrome:



Diseases related to staphylococcal toxic shock syndrome

Symptoms & Phenotypes for Staphylococcal Toxic Shock Syndrome

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Drugs & Therapeutics for Staphylococcal Toxic Shock Syndrome

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Drugs for Staphylococcal Toxic Shock Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Amoxicillinapproved, vet_approvedPhase 446526787-78-033613, 2171
Synonyms:
(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
26787-78-0
33911-69-2
34642-77-8 (mono-hydrochloride salt)
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)
6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid
6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin
6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid
6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI
61336-70-7 (TRIHYDRATE)
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
71447-36-4
81030-75-3
AC-12263
AC1L1PY2
AMC
AMOXICILLIN CRYSTALLINE
AMOXICILLIN PEDIATRIC
AMPC
AUGMENTIN '125'
AUGMENTIN '200'
AUGMENTIN '250'
AUGMENTIN '400'
AUGMENTIN '500'
AUGMENTIN '875'
AUGMENTIN ES-600
AX
Actimoxi
Almodan
Ambap26787-78-0
Amix
Amoclen
Amolin
Amopen
Amopenixin
Amoram
Amox
Amox 250 Cap 250mg
Amox 500 Cap 500mg
Amox S 125 Sus 125mg/5ml
Amox S 250 Sus 250mg/5ml
Amoxi
Amoxi-Mast
Amoxi-mast
Amoxibiotic
Amoxicaps
Amoxicilina
Amoxicilina [INN-Spanish]
Amoxicillin (INN)
Amoxicillin (TN)
Amoxicillin (anhydrous)
Amoxicillin (inn)
Amoxicillin Trihydrate
Amoxicillin and clavulanate potassium
Amoxicillin anhydrous
Amoxicillin pediatric
Amoxicillin trihydrate
Amoxicillin(usan)
Amoxicilline
Amoxicilline [INN-French]
Amoxicilline [INN]
Amoxicilline [inn]
Amoxicillinum
Amoxicillinum [INN-Latin]
Amoxid
Amoxiden
Amoxil
Amoxivet
Amoxycillin
Amoxycillin Trihydrate
Amoxycillin trihydrate
Amoxycillin, BAN
Amoxymed
Amrit
Anemolin
Apo-Amoxi
Apo-Amoxi Cap 250mg
Apo-Amoxi Cap 500mg
Apo-Amoxi Pwr for Susp 125mg/5ml
Apo-Amoxi Pwr for Susp 250mg/5ml
Apo-amoxi
Apo-amoxi sugar free
Aspenil
BL-P 1410
BLP 1410
BPBio1_000499
BRD-K55044200-001-03-9
BRL 2333
BRL-2333
BSPBio_000453
 
Biomox
Bristamox
C06827
CHEBI:2676
CHEBI:53712
CHEMBL1082
CID33613
CPD000058707
Cemoxin
Clamoxyl
Clamoxyl (SKB)
D-(-)-alpha-Amino-p-hydroxybenzyl penicillin
D-(-)-alpha-Amino-p-hydroxybenzylpenicillin
D-(alpha-Amino-p-hydroxybenzyl)penicillin
D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid
D-Amoxicillin
D07452
DB01060
Delacillin
DisperMox
Dispermox
EINECS 248-003-8
Efpenix
Flemoxin
Galenamox
Gen-Amoxicillin 250mg
Gen-Amoxicillin 500mg
HMS1569G15
HSDB 3204
Hiconcil
Histocillin
Hydroxyampicillin
Ibiamox
Imacillin
LS-149721
Lamoxy
Larotid
MLS000028632
MLS002222248
Metafarma capsules
Metifarma capsules
MolPort-003-981-182
MolPort-005-933-687
Moxacin
Moxal
Moxatag
NCGC00179554-01
NSC 277174
NSC277174
Novamoxin Cap 250mg
Novamoxin Cap 500mg
Novamoxin Sus 125mg/5ml
Novamoxin Sus 250mg/5ml
Nu-Amoxi Cap 250mg
Nu-Amoxi Cap 500mg
Nu-Amoxi Sus 125/5ml
Nu-Amoxi Sus 250mg/5ml
Ospamox
P-Hydroxyampicillin
PHL-amoxicillin
PMS-amoxicillin
Pamoxicillin
Piramox
Polymox
Prestwick0_000357
Prestwick1_000357
Prestwick2_000357
Prestwick3_000357
Prestwick_713
Prevpac
Pro Amox Pwr for Oral Susp 125mg/5ml
Pro Amox-250 Cap 250mg
Pro Amox-500 Cap 500mg
Pro-Amox-250 Orl Sus 250mg/5ml
R-Hydroxyampicillin
Rimoxallin
Ro 10-8756
Robamox
SAM002264592
SMR000058707
SPBio_002374
Sauracillin
Sawamox PM
Sumox
Tolodina
Trimox
Unicillin
Utimox
Vetramox
Wymox
Zimox
alpha-Amino-p-hydroxybenzylpenicillin
amoxicillanyl
amoxicillin
p-Hydroxyampicillin
α-amino-p-hydroxybenzylpenicillin
2
RifampinapprovedPhase 434813292-46-15458213, 5381226
Synonyms:
1-b]furan-21-yl acetate
13292-46-1
3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
3-(4-Methylpiperazinyliminomethyl)-rifamycin SV
3-(4-Methylpiperazinyliminomethyl)rifamycin SV
3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV
3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin
46713_FLUKA
46713_RIEDEL
62534-43-4
8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
8-(4-Methylpiperazinyliminomethyl) rifamycin SV
8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin
8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv
8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv
83907_FLUKA
83907_SIGMA
8CI)
AZT + Rifampin
Abrifam
Archidyn
Arficin
Arzide
BA-41166E
BIDD:PXR0014
BPBio1_000561
BSPBio_000509
Ba 41166
Ba 41166/E
Benemicin
Benemycin
Bio-0621
C06688
C43H58N4O12
CAS-13292-46-1
CCRIS 551
CHEBI:28077
CHEBI:455936
CHEMBL180
CID5381226
CID5388984
CID5458213
CID5702112
CID6604339
CID6708473
CID6842115
CID6912767
CID6913622
CPD001906767
D00211
DB01045
DRG-0109
Dione 21-acetate
Dipicin
DivK1c_000550
Doloresum
EINECS 236-312-0
Eremfat
Famcin
Fenampicin
HMS1569J11
HMS1920P08
HMS2089F12
HMS2092G09
HMS501L12
HSDB 3181
KBio1_000550
KBio2_000919
KBio2_003487
KBio2_006055
KBio3_003018
KBioGR_001780
KBioSS_000919
L-5103
L-5103 Lepetit
LS-7689
MLS000028552
MLS001148237
MLS001333745
MolPort-000-767-051
MolPort-002-513-586
MolPort-003-666-281
MolPort-006-395-891
NCGC00016699-01
NCGC00017365-01
NCGC00018178-01
NCGC00022678-03
NCGC00022678-04
NCGC00022678-05
NCGC00160500-01
 
NCI60_000309
NINDS_000550
NSC 113926
NSC-113926
NSC113926
Piperine & Rifampicin
Prestwick0_000525
Prestwick1_000525
Prestwick2_000525
Prestwick3_000525
Prestwick_833
R-Cin
R/AMP
R0079
R3501_SIAL
R3501_SIGMA
R5777_SIGMA
R7382_SIGMA
RAMP
RFP
RMP
Ramp
Reserpine & Rifampicin
Rf
Rfamipicin
Rifa
Rifadin
Rifadin (TN)
Rifadin I.V
Rifadin I.V.
Rifadin IV
Rifadin Iv
Rifadin, Rimactane, Rifampicin, Rifampin
Rifadine
Rifagen
Rifaldazin
Rifaldazine
Rifaldin
Rifam
Rifamicin AMP
Rifamor
Rifampicin
Rifampicin & EEP
Rifampicin & Propolis
Rifampicin (JP15/INN)
Rifampicin SV
Rifampicin [INN:BAN:JAN]
Rifampicina
Rifampicina [INN-Spanish]
Rifampicine
Rifampicine [French]
Rifampicinum
Rifampicinum [INN-Latin]
Rifampin
Rifampin (USP)
Rifampin [USAN]
Rifamsolin
Rifamycin
Rifamycin AMP
Rifamycin Amp
Rifaprodin
Rifcin
Rifinah
Rifobac
Rifoldin
Rifoldine
Riforal
Rimactan
Rimactane
Rimactane (TN)
Rimactazid
Rimactin
Rimactizid
Rimazid
Rimycin
Rofact
S1764_Selleck
SAM002264646
SMR000058322
SMR000653525
SPBio_002430
SPECTRUM1500529
STK080143
Sinerdol
Spectrum3_001837
Spectrum4_001250
Spectrum5_002018
Spectrum_000439
TNP00313
Tubocin
UNII-VJT6J7R4TR
WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1
nchembio884-comp4
rifampin
3
Clindamycinapproved, vet_approvedPhase 417218323-44-929029
Synonyms:
13441-63-9
16669-21-9
18323-44-9
21462-39-5 (mono-hydrochloride)
24620-78-8
24696-19-3
58207-19-5
7(S)-Chloro-7-deoxylincomycin
7-CDL
7-Chloro-7-deoxylincomycin
7-Chlorolincomycin
7-Deoxy-7(S)-chlorolincomycin
AC1L1EGQ
AC1L1GLA
AC1L9JV8
AC1MHD7N
AC1MHE1M
AC1MHUOE
AC1MHX4G
AC1NWAKO
AC1O7ENS
AC1O7GED
AC1OFCIP
AC1OFCIV
AC1OFCJ1
AC1OFCJ7
AC1OIBYJ
AC1OIBYL
AC1OIBYN
AC1Q2V4O
Antirobe
BIDD:GT0418
BPBio1_000236
BRD-A23034328-003-03-4
BSPBio_000214
BSPBio_002049
C06914
C18H33ClN2O5S
CAS-21462-39-5
CHEBI:3745
CHEMBL187
CID2786
CID29029
CID3000512
CID3001928
CID3032758
CID3034218
CID446598
CID5702026
CID6602476
CID6604361
CID7048642
CID7048644
CID7048646
CID7048648
CID7276014
CID7276016
CID7276018
CID9812677
CLDM
CLINDA & IL-12
CLY
Chlolincocin
Chlorlincocin
Chlorodeoxylincomycin
Chlorolincomycin
Cleocin
Cleocin (TN)
Cleocin (tn)
Cleocin HCl
Cleocin Hcl
Cleocin Pediatric
Cleocin Phosphate
Cleocin T
Cleocin T Gel
Cleocin T Lotion
Cleocin T Topical Solution
 
Clinda-Derm
ClindaDerm
Clindagel
Clindamicina
Clindamicina [INN-Spanish]
Clindamycin
Clindamycin & Interleukin 12
Clindamycin & VRC3375
Clindamycin (USAN/INN)
Clindamycin Hcl
Clindamycin Hydrochloride
Clindamycin Phosphate
Clindamycin [USAN:BAN:INN]
Clindamycine
Clindamycine [French]
Clindamycine [INN-French]
Clindamycinum
Clindamycinum [INN-Latin]
Clindesse
Clindets
Clinimycin
D00277
DB01190
Dalacin
Dalacin C
Dalacin C Flavored Granules
Dalacin C Phosphate
Dalacin T Topical Solution
Dalacine
DivK1c_000464
EINECS 242-209-1
Evoclin
HMS2089A05
HMS2089N16
HSDB 3037
I06-0826
IDI1_000464
KBio1_000464
KBio2_000638
KBio2_003206
KBio2_005774
KBio3_001269
KBioGR_000844
KBioSS_000638
Klimicin
Klindan 300
LS-187128
LS-98131
MLS001183714
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
MolPort-002-323-206
MolPort-002-964-479
NCGC00016752-01
NCGC00178843-01
NCGC00179636-01
NINDS_000464
Prestwick0_000137
Prestwick1_000137
Prestwick2_000137
Prestwick3_000137
ResiDerm A
SMP2_000295
SMR000677917
SPBio_000670
SPBio_002153
STK177246
STOCK1N-31150
Sobelin
Spectrum2_000885
Spectrum3_000355
Spectrum4_000292
Spectrum5_001525
Spectrum_000158
U 21251
U-21,251
U-21251
UNII-3U02EL437C
Zindaclin
clindamycin
4Anti-Infective AgentsPhase 422062
5Anti-Bacterial AgentsPhase 411226
6ImmunoglobulinsPhase 4, Phase 26394
7Rho(D) Immune GlobulinPhase 4, Phase 2326
8Immunoglobulins, IntravenousPhase 4, Phase 2333
9gamma-GlobulinsPhase 4, Phase 2326
10Pharmaceutical SolutionsPhase 4, Phase 28192
11AntibodiesPhase 4, Phase 26394
12
ImidaclopridPhase 4187105827-78-986418
Synonyms:
(e)-imidacloprid
(z)-imidacloprid
1-((6-Chloro-3-pyridyl)methyl)-N-nitro-2-imidazolidinimine
1-(2-Chloro-5-pyridylmethyl)-2-(nitroimino)imidazolidine
1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-N-nitro-1H-imidazol-2-amine, 9CI
Admire
Advantage
Advantage flea adulticide
Bayer brand of imidacloprid
 
Confidor
Confidor 200 SL
Confidor SL
Gaucho
Imidacloprid (old RN)
Imidacloprid [iso]
Merit
Merit (insecticide)
Premise 75
Provado
13Antibiotics, AntitubercularPhase 47180
14Clindamycin phosphatePhase 4172
15beta-Lactamase InhibitorsPhase 4294
16Amoxicillin-Potassium Clavulanate CombinationPhase 4137
17Clindamycin palmitatePhase 4172
18Clavulanic AcidPhase 4170
19prolineNutraceuticalPhase 431
20VaccinesPhase 2, Phase 16611
21
Aluminum hydroxideapprovedPhase 121021645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
22Gastrointestinal AgentsPhase 18402
23Anti-Ulcer AgentsPhase 11842
24Adjuvants, ImmunologicPhase 12554
25AntacidsPhase 11842
26methicillin162

Interventional clinical trials:

idNameStatusNCT IDPhase
1Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in ChildrenNot yet recruitingNCT02899702Phase 4
2Efficacy of IntraVenous ImmunoGlobulins in Toxic Shock Syndromes: a Paediatric Pilot StudyRecruitingNCT02219165Phase 2
3Clinical Trial of the BioMed rTSST‐1 Variant Vaccine in Healthy AdultsRecruitingNCT02814708Phase 2
4Phase I STEBVax in Healthy AdultsCompletedNCT00974935Phase 1
5Amendment of rTSST-1 Variant Vaccine Phase 1 Clinical TrialCompletedNCT02971670Phase 1
6rTSST-1 Variant Vaccine Phase 1 First-in-man TrailCompletedNCT02340338Phase 1
7Risk Factors for Early Infant Colonization With Methicillin-Resistant Staphylococcus AureusCompletedNCT01141101

Search NIH Clinical Center for Staphylococcal Toxic Shock Syndrome

Genetic Tests for Staphylococcal Toxic Shock Syndrome

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Anatomical Context for Staphylococcal Toxic Shock Syndrome

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MalaCards organs/tissues related to Staphylococcal Toxic Shock Syndrome:

36
T cells, Monocytes, B cells, Testes

Publications for Staphylococcal Toxic Shock Syndrome

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Articles related to Staphylococcal Toxic Shock Syndrome:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
HLA-DR polymorphisms influence in vivo responses to staphylococcal toxic shock syndrome toxin-1 in a transgenic mouse model. (27863161)
2017
2
Acute encephalopathy with biphasic seizures and late reduced diffusion associated with staphylococcal toxic shock syndrome caused by burns. (27117386)
2016
3
Unusual staphylococcal toxic shock syndrome presenting as a scarlet-like fever. (26543563)
2015
4
Staphylococcal toxic shock syndrome caused by tampon use. (25692047)
2015
5
A fatal case of staphylococcal toxic shock syndrome. (26265799)
2015
6
Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome. (24423010)
2014
7
Staphylococcal toxic shock syndrome: superantigen-mediated enhancement of endotoxin shock and adaptive immune suppression. (24816557)
2014
8
Evidence of Staphylococcal Toxic Shock Syndrome caused by MRSA in a Mother-Newborn Pair. (25260039)
2014
9
Images in clinical medicine. Staphylococcal toxic shock syndrome. (23984732)
2013
10
Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. (22431984)
2012
11
Staphylococcal toxic shock syndrome 2000-2006: epidemiology, clinical features, and molecular characteristics. (21860665)
2011
12
Staphylococcal toxic shock syndrome presenting as acute respiratory distress and cor pulmonale. (20196940)
2010
13
Use of recombinant human activated protein C in nonmenstrual staphylococcal toxic shock syndrome. (21253349)
2010
14
Staphylococcal toxic shock syndrome: mechanisms and management. (21308522)
2010
15
Staphylococcal toxic shock syndrome, superantigenicity, and hypersensitivity. (20367234)
2010
16
Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. (19911998)
2009
17
Evaluation of surveillance methods for staphylococcal toxic shock syndrome. (19402965)
2009
18
Early diagnosis of staphylococcal toxic shock syndrome by detection of the TSST-1 Vbeta signature in peripheral blood of a 12-year-old boy. (18277923)
2008
19
Staphylococcal toxic shock syndrome. (18697637)
2008
20
Staphylococcal toxic shock syndrome toxin-1 induces the translocation and secretion of high mobility group-1 protein from both activated T cells and monocytes. (19009026)
2008
21
Symmetrical Peripheral Gangrene complicating Staphylococcal Toxic Shock Syndrome. (27408131)
2008
22
Analysis of superantigenic toxin Vbeta T-cell signatures produced during cases of staphylococcal toxic shock syndrome and septic shock. (18373692)
2008
23
Staphylococcal toxic-shock-syndrome-toxin-1 as a risk factor for disease relapse in Wegener's granulomatosis. (17409134)
2007
24
A rare case of staphylococcal toxic shock syndrome after abdominoplasty. (19341642)
2007
25
Successful treatment of staphylococcal toxic shock syndrome with linezolid: a case report and in vitro evaluation of the production of toxic shock syndrome toxin type 1 in the presence of antibiotics. (16447124)
2006
26
Reemergence of staphylococcal toxic shock syndrome in the United States since 2000. (15815055)
2005
27
Staphylococcal toxic shock syndrome: still a problem. (16116687)
2005
28
Staphylococcal toxic shock syndrome: still a problem. (15963025)
2005
29
Expansion of TcRalphabeta+CD3+CD4-CD8- (CD4/CD8 double-negative) T lymphocytes in a case of staphylococcal toxic shock syndrome. (15034239)
2004
30
Reemergence of staphylococcal toxic shock syndrome in Minneapolis-St. Paul, Minnesota, during the 2000-2003 surveillance period. (15184497)
2004
31
Human peripheral gammadelta T cells potentiate the early proinflammatory cytokine response to staphylococcal toxic shock syndrome toxin-1. (15122526)
2004
32
A 37-year-old man with a febrile illness. Staphylococcal toxic shock syndrome. (17171845)
2003
33
Staphylococcal toxic shock syndrome in a small infant. (11938403)
2002
34
Bacteremic nonmenstrual staphylococcal toxic shock syndrome associated with enterotoxins A and C. (11170971)
2001
35
Postoperative staphylococcal toxic shock syndrome due to pre-existing staphylococcal infection: case report and review of the literature. (11510574)
2001
36
Staphylococcal toxic shock syndrome. Suspicion and prevention are keys to control. (11675982)
2001
37
Defining a novel domain of staphylococcal toxic shock syndrome toxin-1 critical for major histocompatibility complex class II binding, superantigenic activity, and lethality. (10721486)
2000
38
Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever. (10405382)
1999
39
Staphylococcal toxic shock syndrome toxin-1 inhibits monocyte apoptosis. (10329825)
1999
40
Interaction of staphylococcal toxic shock syndrome toxin-1 and enterotoxin A on T cell proliferation and TNFI+ secretion in human blood mononuclear cells. (22346398)
1999
41
Differential effects of staphylococcal toxic shock syndrome toxin-1 on B cell apoptosis. (8643591)
1996
42
Staphylococcal toxic shock syndrome associated with human immunodeficiency virus infection: report of a case with bacteremia. (8722964)
1996
43
Upregulation of IgE synthesis by staphylococcal toxic shock syndrome toxin-1 in peripheral blood mononuclear cells from patients with atopic dermatitis. (8821303)
1995
44
Staphylococcal toxic shock syndrome in a paediatric burn unit. (7880413)
1994
45
Improved purification and biologic activities of staphylococcal toxic shock syndrome toxin 1. (8253961)
1993
46
Induction of tumor necrosis factor and interleukin-1 by purified staphylococcal toxic shock syndrome toxin 1 requires the presence of both monocytes and T lymphocytes. (1612731)
1992
47
Staphylococcal toxic shock syndrome toxin 1-induced tumor necrosis factor alpha and interleukin-1 beta secretion by human peripheral blood monocytes and T lymphocytes is differentially suppressed by protein kinase inhibitors. (1639516)
1992
48
Mutants of staphylococcal toxic shock syndrome toxin 1: mitogenicity and recognition by a neutralizing monoclonal antibody. (1696937)
1990
49
Causes of staphylococcal toxic shock syndrome. (2380842)
1990
50
Molecular requirements for T cell activation by the staphylococcal toxic shock syndrome toxin-1. (2313089)
1990

Variations for Staphylococcal Toxic Shock Syndrome

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Expression for genes affiliated with Staphylococcal Toxic Shock Syndrome

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Search GEO for disease gene expression data for Staphylococcal Toxic Shock Syndrome.

Pathways for genes affiliated with Staphylococcal Toxic Shock Syndrome

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Pathways related to Staphylococcal Toxic Shock Syndrome according to GeneCards Suite gene sharing:

(show top 50)    (show all 53)
idSuper pathwaysScoreTop Affiliating Genes
19.5HMGB1, TNF
2
Show member pathways
9.4IFNG, TNF
3
Show member pathways
9.4IFNG, TNF
49.4IFNG, TNF
5
Show member pathways
9.4IFNG, TNF
6
Show member pathways
9.4IFNG, TNF
7
Show member pathways
9.2IL1B, TNF
89.2IL1B, TNF
99.2IL1B, TNF
109.2IL1B, TNF
119.2IL1B, TNF
129.2IL1B, TNF
139.2IL1B, TNF
149.2IL1B, TNF
15
Show member pathways
9.0IFNG, IL1B
169.0IFNG, IL1B
17
Show member pathways
8.9IFNG, IGHE, TNF
188.7IGHE, IL1B, TNF
19
Show member pathways
8.6IFNG, IL1B, TNF
20
Show member pathways
8.6IFNG, IL1B, TNF
21
Show member pathways
8.6IFNG, IL1B, TNF
22
Show member pathways
8.6IFNG, IL1B, TNF
23
Show member pathways
8.6IFNG, IL1B, TNF
24
Show member pathways
8.6IFNG, IL1B, TNF
258.6IFNG, IL1B, TNF
26
Show member pathways
8.6IFNG, IL1B, TNF
27
Show member pathways
8.6IFNG, IL1B, TNF
288.6IFNG, IL1B, TNF
298.6IFNG, IL1B, TNF
308.6IFNG, IL1B, TNF
318.6IFNG, IL1B, TNF
32
Show member pathways
8.6IFNG, IL1B, TNF
338.6IFNG, IL1B, TNF
348.6IFNG, IL1B, TNF
358.6IFNG, IL1B, TNF
368.6IFNG, IL1B, TNF
378.6IFNG, IL1B, TNF
388.6IFNG, IL1B, TNF
39
Show member pathways
8.6IFNG, IL1B, TNF
408.6IFNG, IL1B, TNF
418.6IFNG, IL1B, TNF
42
Show member pathways
8.6IFNG, IL1B, TNF
438.6IFNG, IL1B, TNF
448.6CIITA, IFNG, IL1B
45
Show member pathways
8.2CIITA, IFNG, IL1B, TNF
46
Show member pathways
8.2CIITA, IFNG, IL1B, TNF
478.2CIITA, IFNG, IL1B, TNF
488.2CIITA, IFNG, IL1B, TNF
49
Show member pathways
8.2CIITA, IFNG, IL1B, TNF
50
Show member pathways
8.1HMGB1, IFNG, IL1B, TNF

GO Terms for genes affiliated with Staphylococcal Toxic Shock Syndrome

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Cellular components related to Staphylococcal Toxic Shock Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.7IFNG, IGHE, TNF
2extracellular regionGO:00055767.6HMGB1, IFNG, IGHE, IL1B, TNF

Biological processes related to Staphylococcal Toxic Shock Syndrome according to GeneCards Suite gene sharing:

(show all 47)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:004328010.3HMGB1, TNF
2positive regulation of NIK/NF-kappaB signalingGO:190122410.3HMGB1, TNF
3extrinsic apoptotic signaling pathwayGO:009719110.2IFNG, TNF
4humoral immune responseGO:000695910.2IFNG, TNF
5negative regulation of growth of symbiont in hostGO:004413010.2IFNG, TNF
6positive regulation of cell adhesionGO:004578510.2IFNG, TNF
7positive regulation of osteoclast differentiationGO:004567210.2IFNG, TNF
8positive regulation of protein complex assemblyGO:003133410.2IFNG, TNF
9positive regulation of MHC class II biosynthetic processGO:004534810.1CIITA, IFNG
10positive regulation of interleukin-1 beta secretionGO:005071810.1HMGB1, IFNG
11positive regulation of interleukin-12 productionGO:003273510.1HMGB1, IFNG
12lipopolysaccharide-mediated signaling pathwayGO:003166310.0IL1B, TNF
13negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.0IL1B, TNF
14negative regulation of lipid catabolic processGO:005099510.0IL1B, TNF
15positive regulation of vitamin D biosynthetic processGO:006055710.0IFNG, TNF
16positive regulation of fever generationGO:003162210.0IL1B, TNF
17positive regulation of heterotypic cell-cell adhesionGO:003411610.0IL1B, TNF
18positive regulation of interferon-gamma productionGO:003272910.0IL1B, TNF
19protein import into nucleus, translocationGO:000006010.0IFNG, TNF
20positive regulation of interleukin-6 productionGO:003275510.0IL1B, TNF
21positive regulation of interleukin-8 productionGO:003275710.0IL1B, TNF
22positive regulation of NF-kappaB import into nucleusGO:004234610.0IL1B, TNF
23positive regulation of phagocytosisGO:005076610.0IL1B, TNF
24positive regulation of tumor necrosis factor productionGO:00327609.9HMGB1, IFNG
25positive regulation of interleukin-6 secretionGO:20007789.9HMGB1, IL1B
26positive regulation of interleukin-6 biosynthetic processGO:00454109.8IFNG, IL1B
27protein kinase B signalingGO:00434919.8IL1B, TNF
28positive regulation of T cell proliferationGO:00421029.8IFNG, IL1B
29regulation of establishment of endothelial barrierGO:19031409.8IL1B, TNF
30regulation of I-kappaB kinase/NF-kappaB signalingGO:00431229.7IL1B, TNF
31defense response to bacteriumGO:00427429.7IFNG, IGHE, TNF
32positive regulation of apoptotic processGO:00430659.7HMGB1, IFNG, TNF
33regulation of defense response to virus by hostGO:00506919.6IFNG, IL1B
34positive regulation of JNK cascadeGO:00463309.5HMGB1, IL1B, TNF
35positive regulation of calcidiol 1-monooxygenase activityGO:00605599.4IFNG, IL1B, TNF
36positive regulation of chemokine biosynthetic processGO:00450809.4IFNG, IL1B, TNF
37positive regulation of gene expressionGO:00106289.4IFNG, IL1B, TNF
38positive regulation of membrane protein ectodomain proteolysisGO:00510449.4IFNG, IL1B, TNF
39positive regulation of nitric oxide biosynthetic processGO:00454299.4IFNG, IL1B, TNF
40positive regulation of protein phosphorylationGO:00019349.4IFNG, IL1B, TNF
41sequestering of triglycerideGO:00307309.2IL1B, TNF
42negative regulation of transcription from RNA polymerase II promoterGO:00001229.2CIITA, HMGB1, IFNG, TNF
43inflammatory responseGO:00069549.0CIITA, HMGB1, IL1B, TNF
44positive regulation of transcription, DNA-templatedGO:00458938.8CIITA, IFNG, IL1B, TNF
45regulation of insulin secretionGO:00507968.7IFNG, IL1B, TNF
46immune responseGO:00069558.4CIITA, IFNG, IGHE, IL1B, TNF
47positive regulation of transcription from RNA polymerase II promoterGO:00459448.3CIITA, HMGB1, IFNG, IL1B, TNF

Molecular functions related to Staphylococcal Toxic Shock Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.1HMGB1, IFNG, IL1B, TNF

Sources for Staphylococcal Toxic Shock Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet