Staphyloenterotoxemia malady

Disease Ontology: A primary bacterial infectious disease that results in infection located in intestine caused by eating food contaminated with enterotoxins produced by bacteria, has material basis in staphylococcus aureus. the infection has symptom diarrhea, has symptom vomiting, has symptom nausea, has symptom cramps, and has symptom weakness.⁶

MalaCards: Staphyloenterotoxemia, also known as staphylococcal food poisoning, is related to pre-eclampsia and eclampsia, and has symptoms including diarrhea, vomiting and nausea. An important gene associated with Staphyloenterotoxemia is MORF4 (mortality factor 4). The drug magnesium sulfate and the compounds selenium and selenocysteine have been mentioned in the context of this disorder. Affiliated tissues include intestine.

Aliases & Descriptions:

staphyloenterotoxemia 6 8 staphylococcal food poisoning 6 30 43 staphylococcal toxaemia due to food 6

staphyloenterotoxicosis 6 pre-eclampsia 43

Diseases related to staphyloenterotoxemia by text searches and GeneDecks gene sharing:

(show all 39)

id	Related Disease	Score	Top Affiliating Genes
1	pre-eclampsia	14.6
2	eclampsia	14.5
3	lymphocytic leukemia	11.8	SELM, SELV, C11orf31, EPHX2, SELK
4	chronic lymphocytic leukemia	11.5	C11orf31, SELV, EPHX2, SELM, SELK
5	severe pre-eclampsia	11.0
6	mastitis	10.6	EPHX2, TST, FUT2, SELO, SELK, SELM
7	hypertension	10.4
8	toxic shock syndrome	10.2	EPHX2, EPHA4, TST, FUT2, SELO, SELK
9	hellp syndrome	9.4
10	hypoxia	8.5
11	mild pre-eclampsia	8.5
12	essential hypertension	7.9
13	insulin resistance	7.9
14	aldosteronism	7.4
15	down syndrome	7.4
16	homocysteine	7.4
17	preeclampsia/eclampsia 3	6.4
18	preeclampsia/eclampsia 4	6.4
19	periodontal disease	6.4
20	alzheimer's disease	6.4
21	periodontitis	6.4
22	antiphospholipid syndrome	6.4
23	proteinuria	6.4
24	blindness	6.4
25	spontaneous abortion	6.4
26	chorioamnionitis	6.4
27	sepsis	6.4
28	carnitine-acylcarnitine translocase deficiency	6.4
29	thrombophilia	6.4
30	gestational diabetes	6.4
31	thyroiditis	6.4
32	mthfr thermolabile variant	6.4
33	vaginitis	6.4
34	myeloperoxidase deficiency	6.4
35	obesity	6.4
36	placental insufficiency	6.4
37	placental abruption	6.4
38	preeclampsia/eclampsia 1	6.4
39	preeclampsia/eclampsia 2	6.4

Symptoms: diarrhea, vomiting, nausea, cramps, weakness.⁶

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 magnesium sulfate

FMA organs/tissues related to staphyloenterotoxemia:

¹¹

Genes related to staphyloenterotoxemia according to GeneCards:

(show all 15)

id	Symbol	Description	Score	GeneCards Section Context
1	MORF4	mortality factor 4	11.0
2	C11orf31	chromosome 11 open reading frame 31	11.0
3	SELV	selenoprotein V	11.0
4	SELM	selenoprotein M	11.0
5	SELK	selenoprotein K	11.0
6	TST	thiosulfate sulfurtransferase (rhodanese)	11.0
7	TMEM126A	transmembrane protein 126A	11.0	Disorders
8	SELO	selenoprotein O	11.0	Disorders
9	TADA3	transcriptional adaptor 3	11.0	Disorders
10	EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)	11.0	Disorders
11	FUT2	fucosyltransferase 2 (secretor status included)	11.0	Disorders
12	NR4A1	nuclear receptor subfamily 4, group A, member 1	11.0	Disorders
13	EPHA4	EPH receptor A4	11.0	Disorders
14	EPHX2	epoxide hydrolase 2, cytoplasmic	11.0
15	SETBP1	SET binding protein 1	11.0

Compounds related to staphyloenterotoxemia according to GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	selenium32 18	10.5	SELM, SELK, EPT1
2	selenocysteine32 9 18 9	12.2	SELM, SELK, EPT1

Molecular functions related to staphyloenterotoxemia according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	selenium binding	GO:008430	10.0	SELV, C11orf31