SE
MCID: STT001
MIFTS: 59

Status Epilepticus (SE) malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Status Epilepticus

Aliases & Descriptions for Status Epilepticus:

Name: Status Epilepticus 12 50 29 52 42 14 69
Generalized Convulsive Status Epilepticus 50
Grand Mal Status Epilepticus 69
Gcse 50
Se 50

Classifications:



External Ids:

Disease Ontology 12 DOID:1824
MeSH 42 D013226
NCIt 47 C85079
ICD10 33 G41 C84.1 G41.0
UMLS 69 C0038220

Summaries for Status Epilepticus

MalaCards based summary : Status Epilepticus, also known as generalized convulsive status epilepticus, is related to pneumonia and schizophrenia, and has symptoms including seizures, seizures, focal and symptomatic seizures. An important gene associated with Status Epilepticus is POLG (DNA Polymerase Gamma, Catalytic Subunit), and among its related pathways/superpathways are Development HGF signaling pathway and Circadian entrainment. The drugs Ketamine and Midazolam have been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and cortex, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 71 Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more... more...

Related Diseases for Status Epilepticus

Diseases related to Status Epilepticus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 203)
id Related Disease Score Top Affiliating Genes
1 pneumonia 29.2 CALB2 ENO2 GFAP
2 schizophrenia 27.8 BDNF CALB1 CALB2 GAP43 GRIA1 GRIA2
3 idiopathic generalized epilepsy 26.7 BDNF CALB1 CALB2 CASP3 ENO2 FOS
4 norse 12.2
5 febrile infection-related epilepsy syndrome 12.1
6 dravet syndrome 11.5
7 ring chromosome 20 11.3
8 epilepsy, pyridoxine-dependent 11.1
9 chd2 myoclonic encephalopathy 11.0
10 amish infantile epilepsy syndrome 11.0
11 ceroid lipofuscinosis, neuronal, 10 11.0
12 mitochondrial dna depletion syndrome 4a 11.0
13 epileptic encephalopathy, early infantile, 25 11.0
14 epilepsy 10.4
15 neuronitis 10.4
16 encephalopathy 10.3
17 cancerophobia 10.3 CALB1 PVALB
18 encephalitis 10.2
19 fetal and neonatal alloimmune thrombocytopenia 10.2 POLG SCN1A
20 cytomegalovirus disease in patients with impaired cell mediated immunity deemed at risk 10.2 BDNF ENO2 PVALB
21 myelinoclastic diffuse sclerosis 10.2 ENO2 GFAP
22 urea cycle disorder 10.2 BDNF CASP3 GFAP
23 mobitz type ii atrioventricular block 10.2 BDNF NTRK2 SST
24 urinary tract obstruction 10.2 BDNF ENO2 NTRK2
25 cardioauditory syndrome of sanchez cascos 10.1 ENO2 NPY SST
26 splenic marginal zone lymphoma 10.1 BDNF CASP3 GFAP
27 alcohol-related birth defect 10.1 GFAP GRIN2B PVALB
28 temporal lobe epilepsy 10.1
29 cerebritis 10.1
30 myoepithelial carcinoma 10.1 ENO2 GFAP NTRK2 SST
31 breast reconstruction 10.1 BDNF CASP3 ENO2 GFAP
32 neurosyphilis 10.1
33 postmenopausal atrophic vaginitis 10.1 BDNF CASP3 ENO2 NTRK2
34 cystadenoma 10.1 BDNF CASP3 ENO2 NTRK2
35 myopathy mitochondrial cataract 10.1 GRIN2B SCN1A
36 personality disorder 10.0 BDNF FOS GRIN2B PVALB
37 siberian tick typhus 10.0 BDNF FOS LGI1
38 substance-induced psychosis 10.0 BDNF CASP3 GFAP SCN1A
39 ovarian mucinous adenocarcinoma 10.0 BDNF CASP3 GFAP GRIN2B
40 limbic encephalitis 10.0
41 cat-scratch disease 10.0
42 lipedematous scalp 10.0 GRIA1 GRIN2B LGI1
43 retinal telangiectasia 9.9 CALB2 ENO2 SST
44 hepatitis 9.9
45 focal epilepsy 9.9
46 brain injury 9.9
47 meningitis 9.9
48 ellis-van creveld syndrome 9.9 BDNF FOS GRIN2B NTRK2
49 porphyria 9.8
50 lennox-gastaut syndrome 9.8

Comorbidity relations with Status Epilepticus via Phenotypic Disease Network (PDN): (show all 17)


Acute Cystitis Alzheimer Disease
Bronchitis Cerebral Atherosclerosis
Decubitus Ulcer Deficiency Anemia
Encephalopathy Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Hypothyroidism
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Swallowing Disorders
Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Status Epilepticus:



Diseases related to Status Epilepticus

Symptoms & Phenotypes for Status Epilepticus

UMLS symptoms related to Status Epilepticus:


seizures, seizures, focal, symptomatic seizures

MGI Mouse Phenotypes related to Status Epilepticus:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.45 BDNF CALB1 CALB2 CASP3 ENO2 FOS
2 growth/size/body region MP:0005378 10.39 CASP3 ENO2 FOS GAL GAP43 GFAP
3 cellular MP:0005384 10.26 BDNF CASP3 ENO2 FOS GAL GAP43
4 nervous system MP:0003631 10.26 GRIN2B JUN LGI1 NPY NTRK2 POLG
5 homeostasis/metabolism MP:0005376 10.22 GRIA1 GRIA2 GRIN2B JUN NPY NTRK2
6 mortality/aging MP:0010768 10.17 PVALB SCN1A SST BDNF CASP3 FOS
7 integument MP:0010771 10.02 BDNF CASP3 FOS GAL GRIA1 GRIA2
8 hearing/vestibular/ear MP:0005377 9.98 BDNF CALB1 CASP3 FOS GRIA2 NTRK2
9 no phenotypic analysis MP:0003012 9.81 BDNF CASP3 GRIA1 GRIA2 GRIN2B JUN
10 normal MP:0002873 9.77 BDNF SST CALB1 CALB2 FOS GFAP
11 vision/eye MP:0005391 9.23 BDNF CASP3 FOS GAP43 GFAP JUN

Drugs & Therapeutics for Status Epilepticus

Drugs for Status Epilepticus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 75)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 3,Phase 2 6740-88-1 3821
2
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
3
Propofol Approved, Investigational, Vet_approved Phase 3,Phase 2 2078-54-8 4943
4
Thiopental Approved, Vet_approved Phase 3 76-75-5 3000715
5
Clobazam Approved, Illicit Phase 3 22316-47-8 2789
6
Clonazepam Approved, Illicit Phase 3 1622-61-3 2802
7
Lorazepam Approved Phase 3,Phase 2,Phase 1 846-49-1 3958
8
Valproic Acid Approved, Investigational Phase 3,Phase 2 99-66-1 3121
9 Piracetam Approved Phase 3,Phase 2 7491-74-9
10
Phenytoin Approved, Vet_approved Phase 3 57-41-0 1775
11
Diazepam Approved, Illicit, Vet_approved Phase 3,Phase 2 439-14-5 3016
12
Paraldehyde Approved Phase 3 123-63-7 31264
13
Fosphenytoin Approved Phase 3 93390-81-9 56339
14
Topiramate Approved Phase 3 97240-79-4 5284627
15
Ethanol Approved Phase 3 64-17-5 702
16
Lacosamide Approved Phase 3 860352-01-8, 175481-36-4 219078
17
Phenobarbital Approved Phase 3,Phase 2 50-06-6 4763
18
Acetazolamide Approved, Vet_approved Phase 2, Phase 3 59-66-5 1986
19
Pentobarbital Approved, Vet_approved Phase 3 76-74-4 4737
20 Analgesics Phase 3,Phase 2
21 Anesthetics Phase 3,Phase 2
22 Anesthetics, Dissociative Phase 3,Phase 2
23 Anesthetics, General Phase 3,Phase 2
24 Anesthetics, Intravenous Phase 3,Phase 2
25 Anticonvulsants Phase 3,Phase 2,Phase 1
26 Central Nervous System Depressants Phase 3,Phase 2,Phase 1
27 Excitatory Amino Acid Antagonists Phase 3,Phase 2
28 Excitatory Amino Acids Phase 3,Phase 2
29 GABA Agents Phase 3,Phase 2,Phase 1
30 GABA Modulators Phase 3,Phase 2,Phase 1
31 Hypnotics and Sedatives Phase 3,Phase 2,Phase 1
32 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
33 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
34 Anti-Anxiety Agents Phase 3,Phase 2,Phase 1
35 Antiemetics Phase 3,Phase 2,Phase 1
36 Autonomic Agents Phase 3,Phase 2,Phase 1
37 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
38 Psychotropic Drugs Phase 3,Phase 2,Phase 1
39 Tranquilizing Agents Phase 3,Phase 2,Phase 1
40 Antimanic Agents Phase 3,Phase 2
41 Etiracetam Phase 3,Phase 2
42 Neuroprotective Agents Phase 3,Phase 2
43 Nootropic Agents Phase 3,Phase 2
44 Protective Agents Phase 3,Phase 2
45 Diuretics, Potassium Sparing Phase 3
46 Sodium Channel Blockers Phase 3
47 Adjuvants, Anesthesia Phase 3,Phase 2
48 Neuromuscular Agents Phase 3,Phase 2
49 Anti-Obesity Agents Phase 3
50 Calcium, Dietary Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 66)
id Name Status NCT ID Phase
1 Ketamine in Refractory Convulsive Status Epilepticus Unknown status NCT02431663 Phase 3
2 Low Glycemic Index Diet Therapy in Children With Refractory Epilepsy Unknown status NCT01645072 Phase 3
3 Clobazam Use in Epilepsia Partialis Continua - Pilot Study Unknown status NCT02134366 Phase 3
4 Refractory Status Epilepticus Treatment Study Completed NCT01586208 Phase 3
5 Lorazepam for the Treatment of Status Epilepticus or Repetitive Status Epilepticus in Japan Completed NCT02239380 Phase 3
6 Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care Completed NCT01359332 Phase 3
7 Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus Completed NCT00004297 Phase 3
8 Study of Antiepileptic Drug in Generalised Convulsive Status Epilepticus Completed NCT01150331 Phase 3
9 Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medications Completed NCT00809146 Phase 3
10 Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizures (Status 2) Completed NCT00621478 Phase 2, Phase 3
11 Nasal Versus Venous Lorazepam for Control of Acute Seizures in Children Completed NCT00735527 Phase 3
12 Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions Completed NCT00116064 Phase 3
13 An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures. Completed NCT00991757 Phase 3
14 The Study of NPC-06 - Investigation of Safety, Efficacy and Pharmacokinetics of Fosphenytoin Completed NCT00908453 Phase 3
15 A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure Completed NCT00230698 Phase 3
16 Modified Atkins Diet in Childhood Epilepsy Completed NCT00836836 Phase 2, Phase 3
17 Established Status Epilepticus Treatment Trial Recruiting NCT01960075 Phase 3
18 A Study With SAGE-547 for Super-Refractory Status Epilepticus Recruiting NCT02477618 Phase 3
19 Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticus Recruiting NCT01870024 Phase 3
20 Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus Recruiting NCT03115489 Phase 2, Phase 3
21 A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) Recruiting NCT02544763 Phase 3
22 Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus Active, not recruiting NCT02726867 Phase 3
23 Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome Enrolling by invitation NCT02904265 Phase 2, Phase 3
24 An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) Enrolling by invitation NCT02544750 Phase 3
25 Treatment of Refractory Status Epilepticus Terminated NCT00265616 Phase 3
26 Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children. Terminated NCT00343096 Phase 3
27 Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticus Unknown status NCT00362141 Phase 2
28 Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus Completed NCT02052739 Phase 1, Phase 2
29 Levetiracetam Versus Sodium Valproate in Children With Refractory Generalized Convulsive Status Epilepticus Completed NCT02920060 Phase 2
30 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2
31 Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome Active, not recruiting NCT02332655 Phase 1, Phase 2
32 Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus Not yet recruiting NCT03025906 Phase 2
33 Intravenous Levetiracetam as First-line Anticonvulsive Treatment in Patients With Non-convulsive Status Epilepticus Withdrawn NCT00603135 Phase 2
34 Lorazepam for the Treatment of Status Epilepticus in Children Completed NCT00114569 Phase 1
35 Safety and Efficacy of Intravenous Valproate in Pediatric Status Epilepticus and Acute Repetitive Seizures Unknown status NCT01268904
36 EEG in Resuscitated In-hospital Patients Unknown status NCT02349087
37 Prognosis Factors Associated With Convulsive Status Epilepticus in Adults Completed NCT00318578
38 Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment Completed NCT02127918
39 Ketogenic Diet for Refractory Status Epilepticus Completed NCT01796574
40 Putting Electroencephalography (EEG) in the Emergency Department Completed NCT01355211
41 The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study Completed NCT01335425
42 Neuromonitoring of Hepatic Encephalopathy Completed NCT01878305
43 Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment Completed NCT02381977
44 Efficacy Study of Intravenous Sodium Valproate in Addition to First Line Anti Epileptic Treatment of Generalized Convulsive Status Epilepticus. Recruiting NCT01791868
45 TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation Recruiting NCT02056236
46 Creation, Implementation, and Analysis of a Seizure Action Plan Recruiting NCT02995759
47 EEG in In-hospital Patients With Seizure or Altered Mental State Recruiting NCT02383745
48 Smartphone Apps for Pediatric Resuscitation Recruiting NCT02958605
49 Continuous EEG Randomized Trial in Adults Recruiting NCT03129438
50 Assessment of Severity and Prognosis for Patients With Status Epileptics(SE) Recruiting NCT02269137

Search NIH Clinical Center for Status Epilepticus

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: status epilepticus

Genetic Tests for Status Epilepticus

Genetic tests related to Status Epilepticus:

id Genetic test Affiliating Genes
1 Status Epilepticus 29

Anatomical Context for Status Epilepticus

MalaCards organs/tissues related to Status Epilepticus:

39
Brain, Temporal Lobe, Cortex, Heart, Amygdala, Bone, Bone Marrow

Publications for Status Epilepticus

Articles related to Status Epilepticus:

(show top 50) (show all 866)
id Title Authors Year
1
Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice. ( 28079889 )
2017
2
Review and update of the Hong Kong Epilepsy Guideline on status epilepticus. ( 28057897 )
2017
3
Status epilepticus: An overview. ( 28059037 )
2017
4
Fatal Cerebral Edema With Status Epilepticus in Children With Dravet Syndrome: Report of 5 Cases. ( 28330972 )
2017
5
Abnormal neurovascular coupling during status epilepticus migrainosus in Sturge-Weber syndrome. ( 27903813 )
2017
6
Super-refractory Status Epilepticus with Hemophagocytic Syndrome in a Child with HIV Infection. ( 28088756 )
2017
7
Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms. ( 28061403 )
2017
8
Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus. ( 28088683 )
2017
9
Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline. ( 28084627 )
2017
10
Electrical status epilepticus during sleep in Mowat-Wilson syndrome. ( 28501473 )
2017
11
Dentate gyrus autonomous ictal activity in the status epilepticus rat model of epilepsy. ( 28062187 )
2017
12
Diagnosis of Electrical Status Epilepticus During Slow-Wave Sleep With 100 Seconds of Sleep. ( 28045858 )
2017
13
Neuroprotective effect of lithium after pilocarpine-induced status epilepticus in mice. ( 28066149 )
2017
14
Effectiveness of Electroconvulsive Therapy for Refractory Status Epilepticus in Febrile Infection-Related Epilepsy Syndrome. ( 27434885 )
2016
15
Griscelli Syndrome presented with status epilepticus and hemophagocytic lymphohistiocytosis. ( 27095280 )
2016
16
Anticonvulsant effect of argan oil on pilocarpine model induced status epilepticus in wistar rats. ( 27617842 )
2016
17
Simple Partial Status Epilepticus Manifested as Homonymous Hemianopsia: A Rare Intracranial Recording. ( 27162608 )
2016
18
Postictal Prosopometamorphopsia after Focal Status Epilepticus due to Cavernous Hemangioma in the Right Occipital Lobe. ( 27095527 )
2016
19
Teaching NeuroImages: De novo absence status epilepticus in an adult. ( 27164648 )
2016
20
Myoinositol Attenuates the Cell Loss and Biochemical Changes Induced by Kainic Acid Status Epilepticus. ( 27642592 )
2016
21
Isoflurane Use in the Treatment of Super-Refractory Status Epilepticus is Associated with Hippocampal Changes on MRI. ( 28028789 )
2016
22
Relevance of clinical context in the diagnostic-therapeutic approach to status epilepticus. ( 27594403 )
2016
23
Interleukin-1 receptor is a target for adjunctive control of diazepam-refractory status epilepticus in mice. ( 27133574 )
2016
24
Supraventricular Tachycardia During Status Epilepticus in Dravet Syndrome: A Link Between Brain and Heart? ( 26803335 )
2016
25
TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice. ( 28012173 )
2016
26
Outcome scores in status epilepticus - predicting the complex clinical situation. ( 27611303 )
2016
27
Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review. ( 27529037 )
2016
28
Leptomycin B ameliorates vasogenic edema formation induced by status epilepticus via inhibiting p38 MAPK/VEGF pathway. ( 27659963 )
2016
29
Refractory status epilepticus and autoimmune encephalitis with GABAAR and GAD65 antibodies: A case report. ( 26921483 )
2016
30
Dengue encephalitis presenting with nonconvulsive status epilepticus: A case report. ( 27611987 )
2016
31
Treatment of Established Status Epilepticus. ( 27120626 )
2016
32
Status epilepticus associated with pregnancy: A cohort study. ( 27116537 )
2016
33
Refractory status epilepticus due to pneumococcal meningitis in an infant with congenital immunodeficiency. ( 27606021 )
2016
34
Quantitative Evaluation of Medial Temporal Lobe Morphology in Children with Febrile Status Epilepticus: Results of the FEBSTAT Study. ( 27633809 )
2016
35
Pediatric Absence Status Epilepticus: Prolonged Altered Mental Status in an 8-Year-Old Boy. ( 28042487 )
2016
36
Role of anesthetics in treating status epilepticus: One more piece in the puzzle. ( 27664988 )
2016
37
Status Epilepticus Associated With Risperidone and Methylphenidate in an Adolescent With Epilepsy: A Case Report. ( 27662457 )
2016
38
Anterior Temporal Lobectomy for Refractory Status Epilepticus in Herpes Simplex Encephalitis. ( 27473208 )
2016
39
Therapeutic coma for status epilepticus: Differing practices in a prospective multicenter study. ( 27664985 )
2016
40
Changes in serum albumin levels and neutrophil-lymphocyte ratio in patients with convulsive status epilepticus. ( 27161531 )
2016
41
Clinically mild encephalopathy with a reversible splenial lesion and nonconvulsive status epilepticus in a schizophrenic patient with neuroleptic malignant syndrome. ( 27976828 )
2016
42
Intravenous immunoglobulins for refractory status epilepticus, part I: A scoping systematic review of the adult literature. ( 28068584 )
2016
43
Comparison of Intravenous Anesthetic Agents for the Treatment of Refractory Status Epilepticus. ( 27213459 )
2016
44
Pharmacokinetic-Pharmacodynamic Correlation and Brain Penetration of sec-Butylpropylacetamide (SPD), a New CNS Drug Possessing a Unique Activity against Status Epilepticus. ( 27218460 )
2016
45
Role of comorbidities and in-hospital complications in short-term status epilepticus outcome. ( 28088560 )
2016
46
Treatment of Super-Refractory Status Epilepticus in FIRES. ( 28027569 )
2016
47
Intranasal brain-targeted clonazepam polymeric micelles for immediate control of status epilepticus: in vitro optimization, ex vivo determination of cytotoxicity, in vivo biodistribution and pharmacodynamics studies. ( 27648847 )
2016
48
Falling status epilepticus mortality rates in England and Wales: 2001-2013? ( 27173503 )
2016
49
The SAMUKeppra study in prehospital status epilepticus: lessons for future study. ( 28090524 )
2016
50
Managing Status Epilepticus in the Older Adult. ( 27187485 )
2016

Variations for Status Epilepticus

Expression for Status Epilepticus

Search GEO for disease gene expression data for Status Epilepticus.

Pathways for Status Epilepticus

Pathways related to Status Epilepticus according to GeneCards Suite gene sharing:

(show all 22)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.68 BDNF CASP3 FOS JUN NTRK2
2
Show member pathways
12.64 FOS GRIA1 GRIA2 GRIN2B SCN1A
3 12.57 BDNF CASP3 FOS JUN NTRK2
4
Show member pathways
12.46 BDNF FOS GRIA1 GRIA2 GRIN2B NTRK2
5
Show member pathways
12.03 BDNF FOS JUN NTRK2
6 12.01 BDNF CASP3 JUN NTRK2 SST
7
Show member pathways
12 BDNF FOS GRIA1 GRIA2 GRIN2B JUN
8 11.85 BDNF CASP3 FOS GAP43 GFAP
9 11.83 CALB1 ENO2 GAP43 GFAP GRIA1 GRIA2
10
Show member pathways
11.81 CASP3 GRIA1 GRIA2 GRIN2B
11
Show member pathways
11.8 BDNF FOS GRIA1 GRIA2 GRIN2B JUN
12
Show member pathways
11.73 GRIA1 GRIA2 GRIN2B
13 11.72 BDNF CASP3 FOS GRIA1 GRIA2 GRIN2B
14
Show member pathways
11.62 CASP3 FOS JUN
15 11.61 CASP3 FOS JUN
16 11.53 CASP3 FOS JUN
17 11.49 BDNF GRIA1 SST
18 11.32 CALB1 FOS JUN
19 11.26 GRIA1 GRIA2 GRIN2B
20 11.2 CASP3 FOS JUN
21 10.76 BDNF CASP3 NTRK2
22 10.66 FOS JUN

GO Terms for Status Epilepticus

Cellular components related to Status Epilepticus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 synapse GO:0045202 9.7 CALB1 CALB2 GAP43 GRIA1 GRIA2 GRIN2B
2 postsynaptic membrane GO:0045211 9.67 GRIA1 GRIA2 GRIN2B NTRK2
3 neuron projection GO:0043005 9.65 CALB1 CALB2 FOS GRIA1 GRIN2B
4 neuronal cell body GO:0043025 9.5 CALB1 ENO2 GAL GRIA1 PVALB SCN1A
5 transcription factor AP-1 complex GO:0035976 9.32 FOS JUN
6 terminal bouton GO:0043195 9.02 CALB1 CALB2 NTRK2 POLG PVALB

Biological processes related to Status Epilepticus according to GeneCards Suite gene sharing:

(show all 11)
id Name GO ID Score Top Affiliating Genes
1 ion transmembrane transport GO:0034220 9.8 GRIA1 GRIA2 GRIN2B SCN1A
2 response to drug GO:0042493 9.77 CASP3 FOS GAL JUN SST
3 nervous system development GO:0007399 9.73 BDNF FOS GAL GAP43 LGI1 NTRK2
4 excitatory postsynaptic potential GO:0060079 9.63 GRIA1 GRIA2 GRIN2B
5 learning or memory GO:0007611 9.61 CALB1 CASP3 GRIN2B
6 feeding behavior GO:0007631 9.58 GAL NPY NTRK2
7 central nervous system neuron development GO:0021954 9.48 NPY NTRK2
8 regulation of cytosolic calcium ion concentration GO:0051480 9.33 CALB1 CALB2 PVALB
9 brain-derived neurotrophic factor receptor signaling pathway GO:0031547 9.32 BDNF NTRK2
10 ionotropic glutamate receptor signaling pathway GO:0035235 9.13 GRIA1 GRIA2 GRIN2B
11 chemical synaptic transmission GO:0007268 9.02 GRIA1 GRIA2 GRIN2B NPY SST

Molecular functions related to Status Epilepticus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ion channel activity GO:0005216 9.46 GRIA1 GRIA2 GRIN2B SCN1A
2 excitatory extracellular ligand-gated ion channel activity GO:0005231 9.32 GRIA1 GRIA2
3 AMPA glutamate receptor activity GO:0004971 9.26 GRIA1 GRIA2
4 ionotropic glutamate receptor activity GO:0004970 9.13 GRIA1 GRIA2 GRIN2B
5 extracellular-glutamate-gated ion channel activity GO:0005234 8.8 GRIA1 GRIA2 GRIN2B

Sources for Status Epilepticus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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