MCID: STT001
MIFTS: 58

Status Epilepticus

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Status Epilepticus

MalaCards integrated aliases for Status Epilepticus:

Name: Status Epilepticus 12 50 29 52 42 14 69
Generalized Convulsive Status Epilepticus 50
Grand Mal Status Epilepticus 69
Gcse 50
Se 50

Classifications:



External Ids:

Disease Ontology 12 DOID:1824
MeSH 42 D013226
NCIt 47 C85079
ICD10 33 G41 C84.1
UMLS 69 C0038220

Summaries for Status Epilepticus

MalaCards based summary : Status Epilepticus, also known as generalized convulsive status epilepticus, is related to endotheliitis and cavernous hemangioma, and has symptoms including seizures, seizures, focal and symptomatic seizures. An important gene associated with Status Epilepticus is POLG (DNA Polymerase Gamma, Catalytic Subunit), and among its related pathways/superpathways are Development HGF signaling pathway and Circadian entrainment. The drugs Ketamine and Midazolam have been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and cortex, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 72 Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more... more...

Related Diseases for Status Epilepticus

Diseases related to Status Epilepticus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 215)
id Related Disease Score Top Affiliating Genes
1 endotheliitis 30.2 BDNF ENO2 PVALB
2 cavernous hemangioma 30.0 ENO2 GFAP NTRK2
3 schizophrenia 26.2 BDNF CALB1 CALB2 GAP43 GRIA1 GRIA2
4 idiopathic generalized epilepsy 22.2 BDNF CALB1 CALB2 CASP3 ENO2 FOS
5 norse 12.2
6 febrile infection-related epilepsy syndrome 12.1
7 ring chromosome 20 11.3
8 myoclonic astatic epilepsy 11.3
9 epileptic encephalopathy, early infantile, 6 11.2
10 benign familial neonatal epilepsy 11.1
11 epilepsy, pyridoxine-dependent 11.1
12 eastern equine encephalitis 10.9
13 ceroid lipofuscinosis, neuronal, 10 10.9
14 mitochondrial dna depletion syndrome 4a 10.9
15 benign childhood occipital epilepsy, panayiotopoulos type 10.9
16 epileptic encephalopathy, early infantile, 25 10.9
17 chd2 myoclonic encephalopathy 10.9
18 gm3 synthase deficiency 10.9
19 adult central nervous system mature teratoma 10.8 CALB1 PVALB
20 meningitis and encephalitis 10.7 ENO2 GFAP
21 feingold trainer syndrome 10.6 POLG SCN1A
22 intellectual disability-polydactyly-uncombable hair syndrome 10.6 ENO2 GFAP
23 nodular medulloblastoma 10.6 ENO2 GFAP
24 pemphigus foliaceus 10.5 ENO2 SST
25 endocervical adenocarcinoma 10.5 ENO2 SST
26 epilepsy 10.4
27 mobitz type ii atrioventricular block 10.4 BDNF NTRK2 SST
28 spinal stenosis 10.4 BDNF CASP3 GFAP
29 fallopian tube adenomatoid tumor 10.4 BDNF ENO2 NTRK2
30 neuronitis 10.4
31 vulvar benign neoplasm 10.3 ENO2 GFAP
32 carcinoma of unknown primary site, childhood 10.3 ENO2 NPY SST
33 encephalopathy 10.3
34 alcohol-related neurodevelopmental disorder 10.3 GFAP GRIN2B PVALB
35 mixed glioma 10.3 GAL NPY
36 encephalitis 10.2
37 myoglobinuria dominant form 10.2 GRIN2B SCN1A
38 mucopolysaccharidosis iii 10.2 BDNF CALB1 GRIA2 PVALB
39 posterior urethra cancer 10.2 CALB2 ENO2
40 cervical keratinizing squamous cell carcinoma 10.2 ENO2 SST
41 ulcerative colitis 10.2 BDNF CASP3 ENO2 GFAP
42 brain meningioma 10.2 BDNF CASP3 ENO2 GFAP
43 postmenopausal atrophic vaginitis 10.2 BDNF CASP3 ENO2 NTRK2
44 cystadenoma 10.2 BDNF CASP3 ENO2 NTRK2
45 cerebritis 10.1
46 atrial fibrillation, familial, 10 10.1 BDNF CASP3 NTRK2 SST
47 temporal lobe epilepsy 10.1
48 nasal cavity squamous cell carcinoma 10.1 CALB2 ENO2 GFAP
49 neurosyphilis 10.1
50 prostate carcinoma in situ 10.1 BDNF CASP3 GFAP SCN1A

Comorbidity relations with Status Epilepticus via Phenotypic Disease Network (PDN): (show all 17)


Acute Cystitis Alzheimer Disease
Bronchitis Cerebral Atherosclerosis
Decubitus Ulcer Deficiency Anemia
Encephalopathy Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Hypothyroidism
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Swallowing Disorders
Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Status Epilepticus:



Diseases related to Status Epilepticus

Symptoms & Phenotypes for Status Epilepticus

UMLS symptoms related to Status Epilepticus:


seizures, seizures, focal, symptomatic seizures

MGI Mouse Phenotypes related to Status Epilepticus:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.43 BDNF CALB1 CALB2 CASP3 ENO2 FOS
2 growth/size/body region MP:0005378 10.34 BDNF CASP3 ENO2 FOS GAL GAP43
3 cellular MP:0005384 10.23 BDNF CASP3 ENO2 FOS GAL GAP43
4 homeostasis/metabolism MP:0005376 10.18 BDNF CASP3 FOS GAL GFAP GRIA1
5 nervous system MP:0003631 10.16 JUN NPY NTRK2 POLG PVALB SCN1A
6 mortality/aging MP:0010768 10.07 JUN NTRK2 POLG PVALB SCN1A SST
7 integument MP:0010771 9.97 CASP3 FOS GABRA4 GAL GRIA1 GRIA2
8 hearing/vestibular/ear MP:0005377 9.95 BDNF CALB1 CASP3 FOS GRIA2 NTRK2
9 no phenotypic analysis MP:0003012 9.65 CASP3 GABRA4 GRIA1 GRIA2 GRIN2B JUN
10 normal MP:0002873 9.47 FOS GABRA4 GFAP GRIA1 GRIA2 JUN

Drugs & Therapeutics for Status Epilepticus

Drugs for Status Epilepticus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 74)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 3,Phase 2 6740-88-1 3821
2
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
3
Propofol Approved, Investigational, Vet_approved Phase 3,Phase 2 2078-54-8 4943
4
Thiopental Approved, Vet_approved Phase 3 76-75-5 3000715
5
Clobazam Approved, Illicit Phase 3 22316-47-8 2789
6
Clonazepam Approved, Illicit Phase 3 1622-61-3 2802
7
Lorazepam Approved Phase 3,Phase 2,Phase 1 846-49-1 3958
8
Valproic Acid Approved, Investigational Phase 3,Phase 2 99-66-1 3121
9 Piracetam Approved Phase 3,Phase 2 7491-74-9
10
Phenytoin Approved, Vet_approved Phase 3 57-41-0 1775
11
Diazepam Approved, Illicit, Vet_approved Phase 3,Phase 2 439-14-5 3016
12
Paraldehyde Approved Phase 3 123-63-7 31264
13
Topiramate Approved Phase 3 97240-79-4 5284627
14
Fosphenytoin Approved Phase 3 93390-81-9 56339
15
Ethanol Approved Phase 3 64-17-5 702
16
Phenobarbital Approved Phase 3,Phase 2 50-06-6 4763
17
Acetazolamide Approved, Vet_approved Phase 2, Phase 3 59-66-5 1986
18
Pentobarbital Approved, Vet_approved Phase 3 76-74-4 4737
19
Sage Approved, Nutraceutical Phase 3,Phase 1,Phase 2
20
Glutamic Acid Approved, Nutraceutical Phase 2, Phase 3 56-86-0 33032
21 Strawberry Approved, Nutraceutical Phase 3
22 Etiracetam Investigational Phase 3,Phase 2 33996-58-6
23 Analgesics Phase 3,Phase 2
24 Anesthetics Phase 3,Phase 2
25 Anesthetics, Dissociative Phase 3,Phase 2
26 Anesthetics, General Phase 3,Phase 2
27 Anesthetics, Intravenous Phase 3,Phase 2
28 Anticonvulsants Phase 3,Phase 2,Phase 1
29 Central Nervous System Depressants Phase 3,Phase 2,Phase 1
30 Excitatory Amino Acid Antagonists Phase 3,Phase 2
31 Excitatory Amino Acids Phase 3,Phase 2
32 GABA Agents Phase 3,Phase 2,Phase 1
33 GABA Modulators Phase 3,Phase 2,Phase 1
34 Hypnotics and Sedatives Phase 3,Phase 2,Phase 1
35 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
36 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
37 Anti-Anxiety Agents Phase 3,Phase 2,Phase 1
38 Antiemetics Phase 3,Phase 2,Phase 1
39 Autonomic Agents Phase 3,Phase 2,Phase 1
40 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
41 Psychotropic Drugs Phase 3,Phase 2,Phase 1
42 Tranquilizing Agents Phase 3,Phase 2,Phase 1
43 Antimanic Agents Phase 3,Phase 2
44 Neuroprotective Agents Phase 3,Phase 2
45 Nootropic Agents Phase 3,Phase 2
46 Protective Agents Phase 3,Phase 2
47 Diuretics, Potassium Sparing Phase 3
48 Sodium Channel Blockers Phase 3
49 Adjuvants, Anesthesia Phase 3,Phase 2
50 Neuromuscular Agents Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 69)

id Name Status NCT ID Phase Drugs
1 Ketamine in Refractory Convulsive Status Epilepticus Unknown status NCT02431663 Phase 3 Ketamine
2 Low Glycemic Index Diet Therapy in Children With Refractory Epilepsy Unknown status NCT01645072 Phase 3
3 Clobazam Use in Epilepsia Partialis Continua - Pilot Study Unknown status NCT02134366 Phase 3 Clobazam;Clonazepam;Lorazepam
4 Refractory Status Epilepticus Treatment Study Completed NCT01586208 Phase 3 valproic acid (VPA)
5 Lorazepam for the Treatment of Status Epilepticus or Repetitive Status Epilepticus in Japan Completed NCT02239380 Phase 3 Lorazepam
6 Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care Completed NCT01359332 Phase 3
7 A Study With SAGE-547 for Super-Refractory Status Epilepticus Completed NCT02477618 Phase 3 SAGE-547;Placebo
8 Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus Completed NCT00004297 Phase 3 diazepam;lorazepam
9 Study of Antiepileptic Drug in Generalised Convulsive Status Epilepticus Completed NCT01150331 Phase 3 Levetiracetam/Clonazepam;Clonazepam/Placebo levetiracetam IV
10 Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medications Completed NCT00809146 Phase 3 Intramuscular route of active treatment;Intravenous route of active treatment
11 Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizures (Status 2) Completed NCT00621478 Phase 2, Phase 3 lorazepam or diazepam
12 Nasal Versus Venous Lorazepam for Control of Acute Seizures in Children Completed NCT00735527 Phase 3 Lorazepam;Lorazepam
13 Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions Completed NCT00116064 Phase 3 intranasal lorazepam;intramuscular paraldehyde
14 An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures. Completed NCT00991757 Phase 3 carisbamate
15 A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure Completed NCT00230698 Phase 3 topiramate
16 The Study of NPC-06 - Investigation of Safety, Efficacy and Pharmacokinetics of Fosphenytoin Completed NCT00908453 Phase 3 fosphenytoin
17 Modified Atkins Diet in Childhood Epilepsy Completed NCT00836836 Phase 2, Phase 3
18 Established Status Epilepticus Treatment Trial Recruiting NCT01960075 Phase 3 Fosphenytoin;Levetiracetam;Valproic acid
19 Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticus Recruiting NCT01870024 Phase 3 Clonazepam;Fosphenytoin;Placebo;Lorazepam
20 Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus Recruiting NCT03115489 Phase 2, Phase 3 Traditional Treatment (Group T);Ketamine Infusion (Group K)
21 A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) Recruiting NCT02544763 Phase 3 GWP42003-P;Placebo
22 Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome Enrolling by invitation NCT02904265 Phase 2, Phase 3 Diazepam;Acetazolamide
23 An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) Enrolling by invitation NCT02544750 Phase 3 GWP42003-P
24 Treatment of Refractory Status Epilepticus Terminated NCT00265616 Phase 3 propofol;thiopental/pentobarbital
25 Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children. Terminated NCT00343096 Phase 3 Lorazepam
26 Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus Withdrawn NCT02726867 Phase 3 levetiracetam;lacosamide;Ketamine;Phenobarbital
27 Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticus Unknown status NCT00362141 Phase 2 levetiracetam (add-on)
28 Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus Completed NCT02052739 Phase 1, Phase 2 SAGE-547
29 Levetiracetam Versus Sodium Valproate in Children With Refractory Generalized Convulsive Status Epilepticus Completed NCT02920060 Phase 2 Intravenous levetiracetam;Sodium valproate
30 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
31 Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus Recruiting NCT03025906 Phase 2 Phenobarbital;Valproate
32 Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome Active, not recruiting NCT02332655 Phase 1, Phase 2 Cannabidiol
33 Intravenous Levetiracetam as First-line Anticonvulsive Treatment in Patients With Non-convulsive Status Epilepticus Withdrawn NCT00603135 Phase 2 first-line i/v-levetiracetam
34 Lorazepam for the Treatment of Status Epilepticus in Children Completed NCT00114569 Phase 1 lorazepam
35 Safety and Efficacy of Intravenous Valproate in Pediatric Status Epilepticus and Acute Repetitive Seizures Unknown status NCT01268904 Valproate
36 EEG in In-hospital Patients With Seizure or Altered Mental State Unknown status NCT02383745
37 EEG in Resuscitated In-hospital Patients Unknown status NCT02349087
38 Comparing Simplified EEG Monitoring Tool With Standard EEG Monitoring in Patients With Acute Neurological Insult Unknown status NCT02545816
39 Prognosis Factors Associated With Convulsive Status Epilepticus in Adults Completed NCT00318578
40 Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment Completed NCT02127918 ESES treated with clobazam
41 Ketogenic Diet for Refractory Status Epilepticus Completed NCT01796574
42 Putting Electroencephalography (EEG) in the Emergency Department Completed NCT01355211
43 Smartphone Apps for Pediatric Resuscitation Completed NCT02958605
44 The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study Completed NCT01335425
45 Neuromonitoring of Hepatic Encephalopathy Completed NCT01878305
46 Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment Completed NCT02381977
47 Efficacy Study of Intravenous Sodium Valproate in Addition to First Line Anti Epileptic Treatment of Generalized Convulsive Status Epilepticus. Recruiting NCT01791868 Intravenous Sodium Valproate;Placebo
48 TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation Recruiting NCT02056236 Anti-epileptic drugs
49 Creation, Implementation, and Analysis of a Seizure Action Plan Recruiting NCT02995759
50 Continuous EEG Randomized Trial in Adults Recruiting NCT03129438

Search NIH Clinical Center for Status Epilepticus

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: status epilepticus

Genetic Tests for Status Epilepticus

Genetic tests related to Status Epilepticus:

id Genetic test Affiliating Genes
1 Status Epilepticus 29

Anatomical Context for Status Epilepticus

MalaCards organs/tissues related to Status Epilepticus:

39
Brain, Temporal Lobe, Cortex, Liver, Heart, Amygdala, Bone

Publications for Status Epilepticus

Articles related to Status Epilepticus:

(show top 50) (show all 889)
id Title Authors Year
1
The role of necroptosis in status epilepticus-induced brain injury in juvenile rats. ( 28863321 )
2017
2
Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice. ( 28079889 )
2017
3
Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms. ( 28061403 )
2017
4
Management protocols for status epilepticus in the pediatric emergency room: systematic review article. ( 28941387 )
2017
5
Predictors of outcomes and refractoriness in status epilepticus: A prospective study. ( 28866335 )
2017
6
Gyriform Infarction in Cerebral Air Embolism: Imaging Mimicker of Status Epilepticus. ( 28904468 )
2017
7
Abnormal neurovascular coupling during status epilepticus migrainosus in Sturge-Weber syndrome. ( 27903813 )
2017
8
p47Phox/CDK5/DRP1-Mediated Mitochondrial Fission Evokes PV Cell Degeneration in the Rat Dentate Gyrus Following Status Epilepticus. ( 28919853 )
2017
9
Comparison of lacosamide versus sodium valproate in status epilepticus: A pilot study. ( 28919386 )
2017
10
Attenuation of pentylenetrazole-induced acute status epilepticus in rats by adenosine involves inhibition of the mammalian target of rapamycin pathway. ( 28902712 )
2017
11
Status epilepticus: An overview. ( 28059037 )
2017
12
Emergency Neurological Life Support: Status Epilepticus. ( 28913605 )
2017
13
Effect of diet with omega-3 in basal brain electrical activity and during status epilepticus in rats. ( 28892741 )
2017
14
Convulsive status epilepticus in a quaternary hospital paediatric intensive care unit (PICU) in South Africa: An 8 year review. ( 28886496 )
2017
15
Systemic inflammatory response syndrome in the course of status epilepticus: 7-year, two-center observational study. ( 28938136 )
2017
16
Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus. ( 28088683 )
2017
17
Emergency Surgery for Refractory Status Epilepticus. ( 28891483 )
2017
18
An alkaloid extract obtained from Phlegmariurus Saururus induces neuroprotection after status epilepticus. ( 28899505 )
2017
19
Super-refractory Status Epilepticus with Hemophagocytic Syndrome in a Child with HIV Infection. ( 28088756 )
2017
20
A case of rhabdomyolysis after status epilepticus without stroke-like episodes in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. ( 28637934 )
2017
21
Fatal Cerebral Edema With Status Epilepticus in Children With Dravet Syndrome: Report of 5 Cases. ( 28330972 )
2017
22
Electrical status epilepticus during sleep in Mowat-Wilson syndrome. ( 28501473 )
2017
23
Status epilepticus in pregnancy: Etiology, management, and clinical outcomes. ( 28899640 )
2017
24
Evolution of Cerebral Atrophy in a Patient with Super Refractory Status Epilepticus Treated with Barbiturate Coma. ( 28182114 )
2017
25
Dentate gyrus autonomous ictal activity in the status epilepticus rat model of epilepsy. ( 28062187 )
2017
26
Successful surgical management of New Onset Refractory Status Epilepticus (NORSE) presenting with gelastic seizures in a 3A year old girl. ( 28725554 )
2017
27
Neuroprotective effect of lithium after pilocarpine-induced status epilepticus in mice. ( 28066149 )
2017
28
Plasma Exchange as a Therapeutic Modality in a Rare Case of Cryptogenic New Onset Refractory Status Epilepticus (NORSE). ( 28892919 )
2017
29
Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline. ( 28084627 )
2017
30
Spontaneous seizure remission following status epilepticus in drug-resistant epilepsy due to focal cortical dysplasia. ( 28950221 )
2017
31
Diagnosis of Electrical Status Epilepticus During Slow-Wave Sleep With 100 Seconds of Sleep. ( 28045858 )
2017
32
miR-96 attenuates status epilepticus-induced brain injury by directly targeting Atg7 and Atg16L1. ( 28860495 )
2017
33
Electroconvulsive Therapy for Super Refractory Status Epilepticus. ( 28937549 )
2017
34
Review and update of the Hong Kong Epilepsy Guideline on status epilepticus. ( 28057897 )
2017
35
Mitogen- and Stress-Activated Protein Kinase 1 Regulates Status Epilepticus-Evoked Cell Death in the Hippocampus. ( 28870089 )
2017
36
The Clinical Characteristics and Prognostic Analysis of Status Epilepticus in Northeast China. ( 28942441 )
2017
37
Intravenous immunoglobulins for refractory status epilepticus, part I: A scoping systematic review of the adult literature. ( 28068584 )
2016
38
Independent impact of infections on the course and outcome of status epilepticus: a 10-year cohort study. ( 27142712 )
2016
39
Isoflurane Use in the Treatment of Super-Refractory Status Epilepticus is Associated with Hippocampal Changes on MRI. ( 28028789 )
2016
40
Pediatric Absence Status Epilepticus: Prolonged Altered Mental Status in an 8-Year-Old Boy. ( 28042487 )
2016
41
Status epilepticus in a child with influenza A H1N1 infection: An expansion of neurological abnormalities. ( 27606035 )
2016
42
Status epilepticus in scrub typhus. ( 27215700 )
2016
43
Refractory status epilepticus due to pneumococcal meningitis in an infant with congenital immunodeficiency. ( 27606021 )
2016
44
Hippocampal distribution of IL-1I^ and IL-1RI following lithium-pilocarpine-induced status epilepticus in the developing rat. ( 27168372 )
2016
45
New-Onset Refractory Status Epilepticus: More Investigations, More Questions. ( 27462243 )
2016
46
Griscelli Syndrome presented with status epilepticus and hemophagocytic lymphohistiocytosis. ( 27095280 )
2016
47
Treatment of Established Status Epilepticus. ( 27120626 )
2016
48
Electrographic status epilepticus in sleep in an adult with cerebral folate deficiency. ( 26918205 )
2016
49
Therapeutic coma for status epilepticus: Differing practices in a prospective multicenter study. ( 27664985 )
2016
50
Teaching NeuroImages: De novo absence status epilepticus in an adult. ( 27164648 )
2016

Variations for Status Epilepticus

Expression for Status Epilepticus

Search GEO for disease gene expression data for Status Epilepticus.

Pathways for Status Epilepticus

Pathways related to Status Epilepticus according to GeneCards Suite gene sharing:

(show all 22)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.67 BDNF CASP3 FOS JUN NTRK2
2
Show member pathways
12.62 FOS GRIA1 GRIA2 GRIN2B SCN1A
3 12.57 BDNF CASP3 FOS JUN NTRK2
4
Show member pathways
12.46 BDNF FOS GRIA1 GRIA2 GRIN2B NTRK2
5
Show member pathways
12.33 CASP3 GABRA4 JUN NTRK2
6 12.04 BDNF CASP3 JUN NTRK2 SST
7
Show member pathways
12.03 BDNF FOS JUN NTRK2
8
Show member pathways
12 BDNF FOS GRIA1 GRIA2 GRIN2B JUN
9 11.88 BDNF CASP3 FOS GAP43 GFAP
10
Show member pathways
11.84 CASP3 GRIA1 GRIA2 GRIN2B
11 11.83 CALB1 ENO2 GAP43 GFAP GRIA1 GRIA2
12
Show member pathways
11.8 BDNF FOS GRIA1 GRIA2 GRIN2B JUN
13
Show member pathways
11.73 GRIA1 GRIA2 GRIN2B
14 11.72 BDNF CASP3 FOS GRIA1 GRIA2 GRIN2B
15
Show member pathways
11.63 CASP3 FOS JUN
16 11.62 CASP3 FOS JUN
17 11.53 CASP3 FOS JUN
18 11.49 BDNF GRIA1 SST
19 11.32 CALB1 FOS JUN
20 11.27 GABRA4 GRIA1 GRIA2 GRIN2B
21 10.78 BDNF CASP3 NTRK2
22 10.67 FOS JUN

GO Terms for Status Epilepticus

Cellular components related to Status Epilepticus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.72 CALB1 CALB2 FOS GRIA1 GRIN2B
2 postsynaptic membrane GO:0045211 9.65 GABRA4 GRIA1 GRIA2 GRIN2B NTRK2
3 neuronal cell body GO:0043025 9.63 CALB1 GAL GRIA1 PVALB SCN1A SST
4 synapse GO:0045202 9.5 CALB1 CALB2 GABRA4 GAP43 GRIA1 GRIA2
5 transcription factor AP-1 complex GO:0035976 9.37 FOS JUN
6 terminal bouton GO:0043195 9.02 CALB1 CALB2 NTRK2 POLG PVALB

Biological processes related to Status Epilepticus according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.92 BDNF FOS GAL GAP43 NTRK2
2 response to drug GO:0042493 9.77 CASP3 FOS GAL JUN SST
3 excitatory postsynaptic potential GO:0060079 9.63 GRIA1 GRIA2 GRIN2B
4 learning or memory GO:0007611 9.61 CALB1 CASP3 GRIN2B
5 feeding behavior GO:0007631 9.58 GAL NPY NTRK2
6 ion transmembrane transport GO:0034220 9.55 GABRA4 GRIA1 GRIA2 GRIN2B SCN1A
7 central nervous system neuron development GO:0021954 9.51 NPY NTRK2
8 response to wounding GO:0009611 9.48 CASP3 GAP43
9 regulation of cytosolic calcium ion concentration GO:0051480 9.43 CALB1 CALB2 PVALB
10 brain-derived neurotrophic factor receptor signaling pathway GO:0031547 9.32 BDNF NTRK2
11 axon development GO:0061564 9.19 GAP43
12 ionotropic glutamate receptor signaling pathway GO:0035235 9.13 GRIA1 GRIA2 GRIN2B
13 chemical synaptic transmission GO:0007268 9.02 GRIA1 GRIA2 GRIN2B NPY SST

Molecular functions related to Status Epilepticus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular-glutamate-gated ion channel activity GO:0005234 9.33 GRIA1 GRIA2 GRIN2B
2 excitatory extracellular ligand-gated ion channel activity GO:0005231 9.32 GRIA1 GRIA2
3 AMPA glutamate receptor activity GO:0004971 9.26 GRIA1 GRIA2
4 ionotropic glutamate receptor activity GO:0004970 9.13 GRIA1 GRIA2 GRIN2B
5 ion channel activity GO:0005216 9.02 GABRA4 GRIA1 GRIA2 GRIN2B SCN1A

Sources for Status Epilepticus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
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