MCID: STN007
MIFTS: 52

Stenotrophomonas Maltophilia malady

Rare diseases category

Summaries for Stenotrophomonas Maltophilia

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44NIH Rare Diseases, 66Wikipedia, 34MalaCards
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NIH Rare Diseases:44 Stenotrophomonas maltophilia (s. maltophilia) is a type of bacterium that is found in various natural environments (such as soil, water and plants), but also occurs in the hospital environment and may cause infections including those that affect the bloodstream, respiratory tract, urinary tract and surgical-sites. infections are uncommon and typically only occur in individuals with severely impaired immune systems. risk factors in hospitalized individuals may include prior exposure to antimicrobials, mechanical ventilation, and prolonged hospitalization. it typically grows and spreads through medical devices, hospital fluids (such as irrigation solutions or iv fluids) or patient secretions, but does not readily spread between patients. s. maltophilia does not respond to many antibiotics but most strains are susceptible to co-trimoxazole treatment. last updated: 3/2/2012

MalaCards: Stenotrophomonas Maltophilia, also known as stenotrophomonas maltophilia bacteremia, is related to cystic fibrosis and meningitis. An important gene associated with Stenotrophomonas Maltophilia is CCL17 (chemokine (C-C motif) ligand 17), and among its related pathways are IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types and Selected targets of GCR alpha. The compounds mcp 1 and gabexate mesilate have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and lung, and related mouse phenotypes are tumorigenesis and skeleton.

Wikipedia:66 Stenotrophomonas maltophilia is an aerobic, nonfermentative, Gram-negative bacterium. It is an uncommon... more...

Aliases & Classifications for Stenotrophomonas Maltophilia

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44NIH Rare Diseases, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

stenotrophomonas maltophilia 44
stenotrophomonas maltophilia bacteremia 44 63


Related Diseases for Stenotrophomonas Maltophilia

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Stenotrophomonas Maltophilia:



Diseases related to stenotrophomonas maltophilia

Symptoms for Stenotrophomonas Maltophilia

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Drugs & Therapeutics for Stenotrophomonas Maltophilia

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Stenotrophomonas Maltophilia

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Genetic Tests for Stenotrophomonas Maltophilia

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Anatomical Context for Stenotrophomonas Maltophilia

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34MalaCards
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MalaCards organs/tissues related to Stenotrophomonas Maltophilia:

34
Testes, Colon, Lung, Bone marrow, Bone, Liver, Skin, Eye, Myeloid

Animal Models for Stenotrophomonas Maltophilia or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Stenotrophomonas Maltophilia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.2TNF, IFNG, IL10, IL6, IL1B
2MP:00053908.1TNF, IFNG, IL10, IL6, IL1B
3MP:00053818.0TNF, CCL3, IFNG, IL10, IL6
4MP:00036317.6IL1B, IL6, IL10, IFNG, CCL3, TNF
5MP:00053847.4TNF, CCL3, CCL17, IFNG, IL10, IL6
6MP:00053977.1IL1B, TNF, CCL3, CCL17, IFNG, IL10
7MP:00053877.1TNF, CCL3, CCL17, IFNG, IL10, IL8

Publications for Stenotrophomonas Maltophilia

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53PubMed
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Articles related to Stenotrophomonas Maltophilia:

(show top 50)    (show all 486)
idTitleAuthorsYear
1
Antimicrobial susceptibility and combination testing of invasive Stenotrophomonas maltophilia isolates. (23113657)
2013
2
Antimicrobial susceptibility of stenotrophomonas maltophilia isolates from Korea, and the activity of antimicrobial combinations against the isolates. (23341713)
2013
3
Different utilizable substrates have different effects on cometabolic fate of imidacloprid in Stenotrophomonas maltophilia. (23053094)
2013
4
Smqnr variants in clinical isolates of Stenotrophomonas maltophilia in Brazil. (24213195)
2013
5
Genome Sequence of Stenotrophomonas maltophilia Strain AU12-09, Isolated from an Intravascular Catheter. (23640378)
2013
6
Influence of metal ions on bioremediation activity of protocatechuate 3,4-dioxygenase from Stenotrophomonas maltophilia KB2. (23014843)
2013
7
Coordinate hyperproduction of SmeZ and SmeJK efflux pumps extends drug resistance in Stenotrophomonas maltophilia. (23147729)
2013
8
Effect of copper(II) on biodegradation of benzo[a]pyrene by Stenotrophomonas maltophilia. (23141841)
2013
9
Involvement of mutation in ampD I, mrcA, and at least one additional gene in I^-lactamase hyperproduction in Stenotrophomonas maltophilia. (23979761)
2013
10
Simple, time saving pulsed-field gel electrophoresis protocol for the typing of Stenotrophomonas maltophilia. (23756145)
2013
11
Re: "Dacryocystitis secondary to Stenotrophomonas maltophilia infection. (22785591)
2012
12
Comparative in vitro efficacies of ethanol-, EDTA- and levofloxacin-based catheter lock solutions on eradication of Stenotrophomonas maltophilia biofilms. (22580911)
2012
13
Stenotrophomonas maltophilia in Malaysia: molecular epidemiology and trimethoprim-sulfamethoxazole resistance. (22698885)
2012
14
Stenotrophomonas maltophilia in the respiratory tract of medical intensive care unit patients. (22057419)
2012
15
Clinical characteristics of Stenotrophomonas maltophilia infection in hematopoietic stem cell transplantation recipients: a single center experience. (20425134)
2010
16
Stenotrophomonas maltophilia bacteraemia in 40 haematology patients: risk factors, therapy and outcome. (19802036)
2010
17
Stenotrophomonas maltophilia endocarditis of prosthetic mitral valve. (20720357)
2010
18
Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations. (20097818)
2010
19
Comparison of different antimicrobial susceptibility testing methods for Stenotrophomonas maltophilia and results of synergy testing. (20449623)
2010
20
Colistin susceptibility testing: evaluation of reliability for cystic fibrosis isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophilia. (20430789)
2010
21
Optimization of culture media for enhanced chitinase production from a novel strain of Stenotrophomonas maltophilia using response surface methodology. (21124068)
2010
22
AmpDI is involved in expression of the chromosomal L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. (19414581)
2009
23
Codon usage and gene expression pattern of Stenotrophomonas maltophilia R551-3 for pathogenic mode of living. (19769943)
2009
24
Isolation and characterization of a novel strain of Stenotrophomonas maltophilia possessing various dioxygenases for monocyclic hydrocarbon degradation. (24031359)
2009
25
Hydroxylation of thiacloprid by bacterium Stenotrophomonas maltophilia CGMCC1.1788. (19421875)
2009
26
Antimicrobial susceptibility profile of contemporary clinical strains of Stenotrophomonas maltophilia isolates: can moxifloxacin activity be predicted by levofloxacin MIC results? (18343741)
2008
27
The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants. (18419807)
2008
28
The emergence of Stenotrophomonas maltophilia. (18556278)
2008
29
Biofilm formation by Stenotrophomonas maltophilia isolates from device-associated nosocomial infections. (18390153)
2007
30
Stenotrophomonas maltophilia infection of the central venous catheter and lysis of an old thrombosis in a post-bone marrow transplantation child: implications in the fibrinolytic process. (17454909)
2007
31
The immunomodulatory effect of antibiotics on the secretion of tumour necrosis factor alpha by peripheral blood mononuclear cells in response to Stenotrophomonas maltophilia stimulation. (17087095)
2006
32
Differential biofilm formation and motility associated with lipopolysaccharide/exopolysaccharide-coupled biosynthetic genes in Stenotrophomonas maltophilia. (16585771)
2006
33
Combined acanthamoeba and Stenotrophomonas maltophilia keratitis treated with a conjunctival flap followed by penetrating keratoplasty. (16783158)
2006
34
Acute upper airway obstruction caused by Stenotrophomonas maltophilia soft tissue infection. (16191891)
2005
35
Trimethoprim-sulfamethoxazole in the treatment of Stenotrophomonas maltophilia osteomyelitis. (15844086)
2005
36
Antibiotic susceptibility of Stenotrophomonas maltophilia in the presence of lactoferrin. (16189141)
2005
37
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. (15672091)
2005
38
Analysis of sequence variation among smeDEF multi drug efflux pump genes and flanking DNA from defined 16S rRNA subgroups of clinical Stenotrophomonas maltophilia isolates. (15254029)
2004
39
Phenotypic properties, drug susceptibility and genetic relatedness of Stenotrophomonas maltophilia clinical strains from seven hospitals in Rio de Janeiro, Brazil. (15078532)
2004
40
Metabolite repression inhibits degradation of benzo[a]pyrene and dibenz[a,h]anthracene by Stenotrophomonas maltophilia VUN 10,003. (12074057)
2002
41
In vitro activity of clinafloxacin in comparison with other quinolones against Stenotrophomonas maltophilia clinical isolates in the presence and absence of reserpine. (11858908)
2002
42
Selective (R)-3-hydroxylation of FA by Stenotrophomonas maltophilia. (11942484)
2002
43
Two episodes of Stenotrophomonas maltophilia endocarditis of prosthetic mitral valve: report of a case and review of the literature. (11961315)
2002
44
Absolute configuration of 3-hydroxy acids formed by Stenotrophomonas maltophilia: application of multidimensional gas chromatography and circular dichroism spectroscopy. (11748801)
2002
45
Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis. (11897598)
2002
46
Antibiotic resistance surveillance of Stenotrophomonas maltophilia, 1993-1999. (11418532)
2001
47
Long-term preservation of strains of Burkholderia cepacia, Pseudomonas spp. and Stenotrophomonas maltophilia isolated from patients with cystic fibrosis. (11442821)
2001
48
In vitro susceptibility of Stenotrophomonas maltophilia to various antimicrobial combinations. (11687317)
2001
49
Acral necrosis by Stenotrophomonas maltophilia. (11730046)
2001
50
Biological Control of Bipolaris sorokiniana on Tall Fescue by Stenotrophomonas maltophilia Strain C3. (18944711)
1999

Variations for Stenotrophomonas Maltophilia

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Expression for genes affiliated with Stenotrophomonas Maltophilia

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Stenotrophomonas Maltophilia

Search GEO for disease gene expression data for Stenotrophomonas Maltophilia.

Pathways for genes affiliated with Stenotrophomonas Maltophilia

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51PathCards, 55R&D Systems, 13EMD Millipore, 39NCBI BioSystems Database, 61Thomson Reuters, 31KEGG, 54QIAGEN, 56Reactome
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Pathways related to Stenotrophomonas Maltophilia according to GeneCards/GeneDecks:

(show top 50)    (show all 66)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6IL1B, IL6
29.2IL1B, IL6, IL8
3
Show member pathways
9.1IFNG, IL6, IL1B
4
Show member pathways
Immune response IL 12 induced IFN gamma production61
9.1CCL3, IFNG, IL1B
59.1IL6, IL8, IFNG
69.1IFNG, IL8, IL6
79.0IL1B, IFNG, TNF
89.0TNF, IFNG, IL1B
9
Show member pathways
Calcium signaling in the CD4+ TCR pathway39
9.0TNF, IFNG, IL8
109.0IL1B, IL6, TNF
119.0TNF, CCL3, IL1B
128.6TNF, IL10, IL6, IL1B
13
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways61
Immune response IL 1 signaling pathway61
8.5IL1B, IL6, IL8, TNF
14
Show member pathways
8.5TNF, IL8, IL6, IL1B
15
Show member pathways
8.5TNF, CCL3, IFNG, IL10
16
Show member pathways
thioredoxin pathway39
8.5TNF, IFNG, IL6, IL1B
178.5TNF, IFNG, IL6, IL1B
188.5IL6, IL8, IFNG, TNF
19
Show member pathways
8.4IL8, CCL17, CCL3, CXCL2
20
Show member pathways
8.4IL8, CCL17, CCL3, CXCL2
218.2IL1B, IL8, CXCL2, TNF
228.2TNF, IL10, IL8, IL6, IL1B
238.2TNF, IL10, IL8, IL6, IL1B
248.2IL1B, IL6, IL8, IFNG, CCL3
25
Show member pathways
BCR signaling pathway39
TCR Signaling Pathway39
8.2TNF, IFNG, IL10, IL6, IL1B
26
Show member pathways
8.2TNF, IFNG, IL10, IL6, IL1B
27
Show member pathways
IL27-mediated signaling events39
8.2TNF, IFNG, IL10, IL6, IL1B
288.2TNF, IFNG, IL10, IL6, IL1B
29
Show member pathways
8.2TNF, IFNG, IL10, IL6, IL1B
30
Show member pathways
IL23-mediated signaling events39
Immune response IL 10 signaling pathway61
Angiopoietin receptor Tie2-mediated signaling39
Development PDGF signaling via STATs and NF kB61
Development Angiopoietin Tie2 signaling61
8.2IL1B, IL6, IL10, IFNG, TNF
318.2IL1B, IL6, IL10, IFNG, TNF
328.1TNF, CXCL2, IL6, IL1B
33
Show member pathways
Immune response MIF in innate immunity response61
8.1TNF, IFNG, IL8, IL6, IL1B
34
Show member pathways
Transcription NF kB signaling pathway61
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response61
8.1IL1B, IL6, IL8, IFNG, TNF
35
Show member pathways
8.1IL1B, IL6, IL8, IFNG, TNF
367.7TNF, IFNG, IL10, IL8, IL6, IL1B
377.7TNF, IFNG, IL10, IL8, IL6, IL1B
387.7TNF, IFNG, IL10, IL8, IL6, IL1B
397.7TNF, CXCL2, IL8, IL6, IL1B
40
Show member pathways
7.7TNF, CXCL2, IL8, IL6, IL1B
417.6TNF, CCL3, IFNG, IL8, IL6, IL1B
42
Show member pathways
7.4CXCL2, CCL3, IFNG, IL8, IL6, IL1B
437.3IL1B, IL6, IL10, IFNG, CXCL2, TNF
447.3TNF, CXCL2, IFNG, IL8, IL6, IL1B
45
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
7.2TNF, CCL3, IFNG, IL10, IL8, IL6
46
Show member pathways
6.9TNF, CCL3, CCL17, IFNG, IL10, IL8
47
Show member pathways
6.6IL6, IL8, IL10, CCL17, CCL3, CXCL2
48
Show member pathways
6.6TNF, CXCL2, CCL3, CCL17, IL10, IL8
49
Show member pathways
6.6TNF, IL1B, IL6, IL8, IL10, CCL17
50
Show member pathways
6.1TNF, CXCL2, CCL3, CCL17, IFNG, IL10

Compounds for genes affiliated with Stenotrophomonas Maltophilia

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Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 12DrugBank, 52PharmGKB, 25HMDB, 3BitterDB
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Compounds related to Stenotrophomonas Maltophilia according to GeneCards/GeneDecks:

(show top 50)    (show all 179)
idCompoundScoreTop Affiliating Genes
1mcp 1468.9IL10, IL6, IL8, CCL3
2gabexate mesilate468.8TNF, IL8, IL6, IL10
3gold sodium thiomalate468.8TNF, IL1B, IL8, IFNG
4vesnarinone468.8TNF, IL1B, IL6, IFNG
5ulinastatin468.8TNF, IL6, IL10, IL8
65 aminosalicylic acid468.7IL1B, IL8, IL10, TNF
7staurosporin468.6TNF, IL8, IL1B, IFNG
8toxin-1468.6IL1B, IL8, IL10, CCL3, TNF
9taurine chloramine468.5IFNG, TNF, IL1B, IL6, IL8
10imiquimod46 62 30 1211.5IL10, TNF, IFNG, IL8, IL6
11infliximab46 52 1210.4IL1B, TNF, IFNG, IL10, IL6
12ivig468.4IL10, IFNG, IL6, IL1B, TNF
138-isoprostane468.4TNF, CCL3, IL8, IL6, IL10
14adalimumab46 52 1210.2TNF, IFNG, IL10, IL6
15thalidomide46 52 62 1211.2IL1B, IL6, IFNG, TNF, IL10
16il-12468.2TNF, IFNG, IL10, IL6, IL1B, IL8
17etanercept46 52 1210.2IL1B, IL6, IL8, IL10, IFNG, TNF
18pentoxifylline46 129.1IL1B, IL6, IL8, IL10, IFNG, TNF
1915-deoxy-delta-12,14-prostaglandin j2468.1IFNG, IL1B, IL6, IL8, IL10, TNF
20mip 1alpha468.1TNF, CCL3, IL1B, IL6, IL8, IL10
21peptidoglycan46 309.1TNF, CCL3, IL6, IL1B, IL8, IL10
22triptolide468.0IFNG, IL1B, IL6, CCL3, IL8, TNF
23poly(i-c)468.0IFNG, IL8, IL6, CCL3, TNF, IL1B
24leukotriene b446 62 259.9TNF, CCL3, IL1B, IL8, IL6
25pdtc467.9IL1B, IL6, IL8, CCL3, IFNG, TNF
26simvastatin46 52 62 30 25 1212.9IL6, TNF, IFNG, IL10, IL8, CCL3
27polymyxin b467.9IL6, IL8, TNF, BPI, IFNG, IL10
28lipoteichoic acid467.8IL1B, IL6, IL8, IL10, CCL3, BPI
29rantes467.7CCL3, IL1B, IL8, IL10, IFNG, CCL17
30polyinosinic-polycytidylic acid467.7TNF, CCL3, IFNG, IL10, IL8, IL6
31neopterin467.7IL1B, IL6, IL8, IFNG, CCL3, TNF
32gm-csf46 308.7CCL3, IL1B, IL6, IFNG, IL10, IL8
33hydrocortisone46 3 62 1210.6IFNG, IL10, IL1B, CCL3, IL8, TNF
34cyclosporin a46 30 629.6CCL17, IFNG, CCL3, TNF, IL10, IL6
35actinomycin d467.6TNF, CCL3, IFNG, IL8, IL6, IL1B
36histamine46 30 259.6IL6, IL10, IL1B, IFNG, TNF, CCL3
37sp 60012546 628.5IL8, CCL3, CXCL2, TNF, IL6, IL1B
38tarc467.4TNF, CXCL2, CCL3, CCL17, IFNG, IL8
39il 10467.4TNF, CCL3, CCL17, IFNG, IL10, IL8
40cycloheximide467.3CCL3, IL1B, IL8, IL6, TNF, IFNG
41groalpha467.3IL6, IL8, IL10, CCL3, CXCL2, TNF
42lactate467.2IL8, IL6, BPI, DHFR, TNF, CXCL2
43ly294002467.2IL6, IL10, IL1B, TNF, CXCL2, CCL3
44sb 20358046 627.8IL1B, IL8, CXCL2, IL10, IL6, IFNG
45pge2466.8CCL3, IFNG, CXCL2, TNF, IL10, IL6
46ccl346 307.6IL1B, IL6, IL8, TNF, CXCL2, CCL3
47endotoxin466.5IL1B, IL6, IL8, IL10, IFNG, CCL3
48dexamethasone46 52 30 129.5CXCL2, IL1B, IL6, IL8, IL10, IFNG
49vegf466.5IL1B, TNF, CXCL2, BPI, CCL3, IFNG
50nitric oxide46 25 128.2IL8, TNF, CXCL2, BPI, CCL3, CCL17

GO Terms for genes affiliated with Stenotrophomonas Maltophilia

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17Gene Ontology
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Cellular components related to Stenotrophomonas Maltophilia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.9IL6, IFNG, TNF
2extracellular regionGO:0055766.2TNF, CXCL2, CCL3, CCL17, IFNG, IL8
3extracellular spaceGO:0056156.0IL1B, TNF, CXCL2, CCL3, CCL17, IFNG

Biological processes related to Stenotrophomonas Maltophilia according to GeneCards/GeneDecks:

(show top 50)    (show all 70)
idNameGO IDScoreTop Affiliating Genes
1neutrophil apoptotic processGO:00178110.4IL6
2positive regulation of MHC class II biosynthetic processGO:04534810.0IFNG, IL10
3positive regulation of interleukin-6 biosynthetic processGO:0454109.9IFNG, IL1B
4receptor biosynthetic processGO:0328009.9IL10, TNF
5sequestering of triglycerideGO:0307309.9IL1B, TNF
6negative regulation of cytokine secretion involved in immune responseGO:0027409.9TNF, IL10
7positive regulation of heterotypic cell-cell adhesionGO:0341169.8TNF, IL1B
8positive regulation of fever generationGO:0316229.8TNF, IL1B
9positive regulation of vitamin D biosynthetic processGO:0605579.8TNF, IFNG
10regulation of I-kappaB kinase/NF-kappaB signalingGO:0431229.7IL1B, TNF
11epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.6TNF, IL6
12negative regulation of interleukin-6 productionGO:0327159.6IL10, BPI, TNF
13negative regulation of lipid storageGO:0108889.6TNF, IL6
14cellular response to lipopolysaccharideGO:0712229.6IFNG, IL10, IL8
15cell activationGO:0017759.6TNF, CCL3
16defense response to bacteriumGO:0427429.6IL10, IFNG, BPI
17negative regulation of lipid catabolic processGO:0509959.5IL1B, TNF
18positive regulation of T cell proliferationGO:0421029.5IFNG, IL6, IL1B
19positive regulation of interleukin-1 beta secretionGO:0507189.5IFNG, CCL3
20negative regulation of growth of symbiont in hostGO:0441309.5IL10, IFNG, TNF
21positive regulation of calcidiol 1-monooxygenase activityGO:0605599.5TNF, IFNG, IL1B
22positive regulation of chemokine biosynthetic processGO:0450809.5IL1B, IFNG, TNF
23positive regulation of membrane protein ectodomain proteolysisGO:0510449.5TNF, IFNG, IL1B
24defense response to protozoanGO:0428329.4IL6, IFNG
25lipopolysaccharide-mediated signaling pathwayGO:0316639.4TNF, CCL3, IL1B
26protein kinase B signalingGO:0434919.4IL1B, CCL3, TNF
27cellular response to organic cyclic compoundGO:0714079.4IL1B, CCL3, TNF
28positive regulation of interleukin-6 productionGO:0327559.4IL1B, IL6, TNF
29response to molecule of bacterial originGO:0022379.3IL8, IL10, CXCL2
30regulation of insulin secretionGO:0507969.3IL1B, IFNG, TNF
31positive regulation of chemokine productionGO:0327229.3TNF, IL6
32cell-cell signalingGO:0072679.3CCL3, CCL17, IL10, IL1B
33calcium-mediated signalingGO:0197229.3IL8, CCL3, TNF
34MAPK cascadeGO:0001659.3IL1B, CCL3, TNF
35response to glucocorticoidGO:0513849.3TNF, IL10, IL6
36humoral immune responseGO:0069599.3IL6, IFNG, TNF
37neutrophil chemotaxisGO:0305939.2CCL3, IFNG, IL8, IL1B
38embryonic digestive tract developmentGO:0485669.1IL8, TNF
39positive regulation of protein kinase B signalingGO:0518979.1TNF, CCL3, IL6
40positive regulation of NF-kappaB transcription factor activityGO:0510929.1TNF, IL6, IL1B
41positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.0TNF, IL10, IL6, IL1B
42positive regulation of ERK1 and ERK2 cascadeGO:0703749.0TNF, CCL3, IL6
43positive regulation of nitric oxide biosynthetic processGO:0454299.0IL1B, IL6, IFNG, TNF
44response to drugGO:0424938.9TNF, IFNG, IL10, IL6
45chemotaxisGO:0069358.9CXCL2, CCL3, CCL17, IL8
46negative regulation of cell proliferationGO:0082858.8TNF, IL8, IL6, IL1B
47positive regulation of transcription, DNA-templatedGO:0458938.7IL1B, IL6, IL10, TNF
48immune responseGO:0069558.7CXCL2, BPI, CCL17, IL8, IL1B
49positive regulation of transcription from RNA polymerase II promoterGO:0459448.5TNF, IFNG, IL10, IL6, IL1B
50inflammatory responseGO:0069547.0IL1B, IL6, IL8, IL10, CCL17, CCL3

Molecular functions related to Stenotrophomonas Maltophilia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:0080098.4IL8, CCL17, CCL3, CXCL2
2cytokine activityGO:0051257.9IL1B, IL6, IL10, IFNG, TNF

Products for genes affiliated with Stenotrophomonas Maltophilia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
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53PubMed
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63UMLS
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