MCID: STR029
MIFTS: 18

Sternal Cleft malady

Rare diseases category
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Summaries for Sternal Cleft

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Wikipedia:65 Sternal clefts are rare congenital malformations that result from defective embryologic fusion of paired... more...

MalaCards based summary: Sternal Cleft, also known as congenital sternal cleft, is related to phace syndrome and hemangioma, and has symptoms including Affiliated tissues include heart, bone and skin.

Aliases & Classifications for Sternal Cleft

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Sternal Cleft, Aliases & Descriptions:

Name: Sternal Cleft 42 62
 
Congenital Sternal Cleft 42 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Sternal Cleft

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Diseases related to Sternal Cleft via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1phace syndrome10.4
2hemangioma10.3
3patent ductus arteriosus10.3
4congenital heart disease10.3
5tetralogy of fallot10.1
6gastroschisis10.1
7cervicitis10.1
8periostitis10.1
9asternia10.1
10pentalogy of cantrell10.1
11transposition of the great arteries10.1
12aneurysm10.1
13right aortic arch10.1

Graphical network of diseases related to Sternal Cleft:



Diseases related to sternal cleft

Symptoms for Sternal Cleft

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HPO human phenotypes related to Sternal Cleft:

id Description Frequency HPO Source Accession
1 abnormality of the neck hallmark (90%) HP:0000464
2 abnormality of the eye hallmark (90%) HP:0000478

Drugs & Therapeutics for Sternal Cleft

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Drug clinical trials:

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Search NIH Clinical Center for Sternal Cleft

Genetic Tests for Sternal Cleft

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Anatomical Context for Sternal Cleft

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MalaCards organs/tissues related to Sternal Cleft:

32
Heart, Bone, Skin, Liver

Animal Models for Sternal Cleft or affiliated genes

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Publications for Sternal Cleft

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Articles related to Sternal Cleft:

(show top 50)    (show all 76)
idTitleAuthorsYear
1
Mesh-repaired complete sternal cleft complicated by multi-resistant bacterial infection. (25374797)
2014
2
Closing the cleft over a throbbing heart: neonatal sternal cleft. (25100810)
2014
3
Reconstruction of sternal cleft with autologous cartilage graft in an adult. (25178468)
2014
4
Repair of inferior sternal cleft using bilateral sternal bar turnover flaps in a patient with pentalogy of cantrell. (24511499)
2014
5
Sternal Cleft associated with Patent Ductus Arteriosus, Atrial Septal Defect, and Subglottic Hemangioma: A rarity. (24834387)
2014
6
Surgical repair of a congenital sternal cleft in a cat. (24909699)
2014
7
Congenital Sternal Cleft along with Persistent Left-Sided Superior Vena Cava: A Rare Presentation. (23841006)
2013
8
Primary repair of sternal cleft in infancy using combined periosteal flap and sliding osteochondroplasty. (23427313)
2013
9
Incidental detection of superior sternal cleft on Technetium-99m methylene diphosphonate bone scan. (24163521)
2013
10
Congenital sternal cleft. (23164014)
2012
11
Accidental finding on bone scan: isolated upper sternal cleft in an adult. (22228364)
2012
12
Combined repair of upper sternal cleft and transposition of the great arteries in a newborn. (23098954)
2012
13
Phenotypic spectrum and management of sternal cleft: literature review and presentation of a new series. (21737294)
2012
14
Sternal cleft in a neonate- repaired with silastic block and pectoralis major flaps. (21340727)
2011
15
Primary repair of complete sternal cleft in an adult: a 4-year follow-up. (21841884)
2011
16
Complete sternal cleft in an adult: case report. (21850590)
2011
17
Superior sternal cleft, supraumbilical midline raphe and haemangiomas in a baby girl with an ostium secundum ASD. (21233709)
2011
18
E-page original images. A rare case of isolated complete congenital sternal cleft. (21062690)
2010
19
Case report. Isolated complete congenital sternal cleft in an adult: MDCT imaging findings. (19759206)
2009
20
Autologous repair of isolated complete sternal cleft in an adolescent. (20006040)
2009
21
Prenatal diagnosis of a complete sternal cleft in a child with PHACES syndrome-a case report. (19142902)
2009
22
Low cervical skin crease approach for superior sternal cleft repair. (19735841)
2009
23
Isolated superior sternal cleft. (19130978)
2009
24
Congenital medium sternal cleft with partial ectopia cordis repair. (21918661)
2009
25
Sternal cleft, a rare congenital anomaly. Report of the first Tunisian case. (19213519)
2008
26
Thymectomy to achieve primary closure of total sternal cleft. (19040914)
2008
27
Sternal cleft associated with enterogenous cyst treated during the newborn period. (17806026)
2007
28
Congenital sternal cleft in an adult male not associated with cardiac defects or ectopia cordis. (17462433)
2007
29
Sternal cleft--a natural absurdity or a surgical opportunity. (17336207)
2007
30
Superior sternal cleft, cutaneous, and airway haemangiomas. (17185427)
2007
31
Surgical repair of congenital sternal cleft in an adult to prevent traumatic pericardial rupture. (17151973)
2006
32
Surgical repair of combined gastroschisis and sternal cleft. (15991160)
2005
33
Superior sternal cleft associated with PHACES syndrome: postnatal sonographic findings. (12636335)
2003
34
Sternal cleft: a surgical opportunity. (12596098)
2003
35
Congenital sternal cleft with patent ductus arteriosus: report of a case. (11871821)
2002
36
Complete congenital sternal cleft associated with pectus excavatum. (12224725)
2002
37
Superior congenital sternal cleft. (11536030)
2001
38
Two patients with varying combinations of sternal cleft, haemangiomas, midline abdominal raphe, coarctation of the aorta with a right aortic arch. (10826620)
2000
39
Upper sternal cleft associated with unusual symptoms. (11145410)
2000
40
Superior sternal cleft: construction with a titanium plate. (9427932)
1998
41
Combined repair of upper sternal cleft and tetralogy of Fallot in an infant. (9262621)
1997
42
Neonatal sternal cleft associated with an extrathoracic cystic mass. (9126771)
1997
43
Primary repair of complete sternal cleft with pectoralis major muscle flaps. (8619730)
1996
44
Congenital skin fistula with sternal cleft. (7718480)
1995
45
Successful repair of complete sternal cleft associated with congenital heart disease. Report of one case. (7721929)
1995
46
Sternal cleft: case report and review of a series of nine patients. (8588577)
1995
47
Complete sternal cleft. (2609075)
1989
48
Aneurysm of the ascending aorta associated with sternal cleft, cutaneous hemangioma, and occlusion of the right innominate artery in a neonate. (3541557)
1987
49
A supraumbilical midline raphAc with sternal cleft in a 47,XXX woman. (3605199)
1987
50
Congenital upper sternal cleft: a case with successful surgical repair. (5419075)
1970

Variations for Sternal Cleft

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Expression for genes affiliated with Sternal Cleft

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Search GEO for disease gene expression data for Sternal Cleft.

Pathways for genes affiliated with Sternal Cleft

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Compounds for genes affiliated with Sternal Cleft

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GO Terms for genes affiliated with Sternal Cleft

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Products for genes affiliated with Sternal Cleft

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  • Antibodies
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Sources for Sternal Cleft

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet