MCID: STR029
MIFTS: 18

Sternal Cleft malady

Category: Rare diseases

Aliases & Classifications for Sternal Cleft

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Aliases & Descriptions for Sternal Cleft:

Name: Sternal Cleft 47 67
 
Congenital Sternal Cleft 47

Classifications:



Summaries for Sternal Cleft

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Wikipedia:70 Sternal clefts are rare congenital malformations that result from defective embryologic fusion of paired... more...

MalaCards based summary: Sternal Cleft, also known as congenital sternal cleft, is related to hemangioma and ectopia cordis, and has symptoms including abnormality of the neck and abnormality of the eye. Affiliated tissues include eye, heart and bone.

Related Diseases for Sternal Cleft

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Diseases related to Sternal Cleft via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1hemangioma10.0
2ectopia cordis10.0
3heart disease9.9
4patent ductus arteriosus9.9
5pentalogy of cantrell9.9
6phace syndrome9.9
7coronary artery disease9.7
8tetralogy of fallot9.7
9artery disease9.7
10gastroschisis9.7
11cervicitis9.7
12thyroiditis9.7
13periostitis9.7
14transposition of the great arteries9.7
15aneurysm9.7
16right aortic arch9.7

Graphical network of diseases related to Sternal Cleft:



Diseases related to sternal cleft

Symptoms for Sternal Cleft

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Human phenotypes related to Sternal Cleft:

 63
id Description HPO Frequency HPO Source Accession
1 abnormality of the neck63 hallmark (90%) HP:0000464
2 abnormality of the eye63 hallmark (90%) HP:0000478

Drugs & Therapeutics for Sternal Cleft

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Sternal Cleft

Genetic Tests for Sternal Cleft

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Anatomical Context for Sternal Cleft

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MalaCards organs/tissues related to Sternal Cleft:

35
Eye, Heart, Bone, Skin, Liver, Thyroid

Animal Models for Sternal Cleft or affiliated genes

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Publications for Sternal Cleft

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Articles related to Sternal Cleft:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Primary Closure of A Sternal Cleft in A Neonate. (27853697)
2016
2
Complete sternal cleft - A rare congenital malformation and its repair in a 3-month-old boy: A case report. (27046980)
2016
3
Incidental finding of sternal cleft on technetium-99m-methylene diphosphonate bone scan appearing as a necklace. (27833326)
2016
4
Upper Sternal Cleft With a Complex Congenital Heart Defect: Repair in a Single Stage. (26777935)
2016
5
Isolated Sternal Cleft in a Patient With Coronary Artery Disease. (26701621)
2016
6
Sternal Cleft Associated with Cantrell's Pentalogy in a German Shepherd Dog. (26083439)
2015
7
Mesh-repaired complete sternal cleft complicated by multi-resistant bacterial infection. (25374797)
2014
8
Reconstruction of sternal cleft with autologous cartilage graft in an adult. (25178468)
2014
9
Repair of inferior sternal cleft using bilateral sternal bar turnover flaps in a patient with pentalogy of cantrell. (24511499)
2014
10
Sternal Cleft associated with Patent Ductus Arteriosus, Atrial Septal Defect, and Subglottic Hemangioma: A rarity. (24834387)
2014
11
Atypical sternal cleft and clavicle agenesis. (24585661)
2014
12
Congenital Sternal Cleft along with Persistent Left-Sided Superior Vena Cava: A Rare Presentation. (23841006)
2013
13
Primary repair of sternal cleft in infancy using combined periosteal flap and sliding osteochondroplasty. (23427313)
2013
14
Incidental detection of superior sternal cleft on Technetium-99m methylene diphosphonate bone scan. (24163521)
2013
15
Congenital sternal cleft. (23164014)
2012
16
Accidental finding on bone scan: isolated upper sternal cleft in an adult. (22228364)
2012
17
Combined repair of upper sternal cleft and transposition of the great arteries in a newborn. (23098954)
2012
18
Phenotypic spectrum and management of sternal cleft: literature review and presentation of a new series. (21737294)
2012
19
Sternal cleft: prenatal multimodality imaging. (22307410)
2012
20
Sternal cleft in a neonate- repaired with silastic block and pectoralis major flaps. (21340727)
2011
21
Complete sternal cleft in an adult: case report. (21850590)
2011
22
Superior sternal cleft, supraumbilical midline raphe and haemangiomas in a baby girl with an ostium secundum ASD. (21233709)
2011
23
E-page original images. A rare case of isolated complete congenital sternal cleft. (21062690)
2010
24
Sternal cleft repair: a report of two cases and review of literature. (20859036)
2010
25
Prenatal diagnosis of a complete sternal cleft in a child with PHACES syndrome-a case report. (19142902)
2009
26
Isolated superior sternal cleft. (19130978)
2009
27
Twenty seven-year experience with sternal cleft repair. (19167236)
2009
28
Case report. Isolated complete congenital sternal cleft in an adult: MDCT imaging findings. (19759206)
2009
29
Sternal cleft associated with enterogenous cyst treated during the newborn period. (17806026)
2007
30
Congenital sternal cleft in an adult male not associated with cardiac defects or ectopia cordis. (17462433)
2007
31
Sternal cleft--a natural absurdity or a surgical opportunity. (17336207)
2007
32
Surgical repair of congenital sternal cleft in an adult to prevent traumatic pericardial rupture. (17151973)
2006
33
Midline raphAc, sternal cleft, and other midline abnormalities: a new dominant syndrome? (15810010)
2005
34
Sternal cleft: a surgical opportunity. (12596098)
2003
35
Complete congenital sternal cleft associated with pectus excavatum. (12224725)
2002
36
Congenital sternal cleft. (11254425)
2001
37
Upper sternal cleft associated with unusual symptoms. (11145410)
2000
38
Multiple pilomatricomas, sternal cleft and mild coagulative defect. (10721855)
2000
39
Repair of congenital sternal cleft in infants and adolescents. (9800797)
1998
40
Superior sternal cleft: construction with a titanium plate. (9427932)
1998
41
Combined repair of upper sternal cleft and tetralogy of Fallot in an infant. (9262621)
1997
42
Neonatal sternal cleft associated with an extrathoracic cystic mass. (9126771)
1997
43
Primary repair of complete sternal cleft with pectoralis major muscle flaps. (8619730)
1996
44
Complete congenital sternal cleft in an adult: repair by autogenous tissues. (8694629)
1996
45
Successful repair of complete sternal cleft associated with congenital heart disease. Report of one case. (7721929)
1995
46
Congenital skin fistula with sternal cleft. (7718480)
1995
47
Sternal cleft associated with vascular anomalies and micrognathia. (8328853)
1993
48
Superior sternal cleft. (3246403)
1988
49
A supraumbilical midline raphAc with sternal cleft in a 47,XXX woman. (3605199)
1987
50
Superior sternal cleft: repair in the newborn. (4004402)
1985

Variations for Sternal Cleft

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Expression for genes affiliated with Sternal Cleft

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Search GEO for disease gene expression data for Sternal Cleft.

Pathways for genes affiliated with Sternal Cleft

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GO Terms for genes affiliated with Sternal Cleft

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Sources for Sternal Cleft

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet