MCID: STR044
MIFTS: 34

Steroid-Resistant Nephrotic Syndrome malady

Categories: Genetic diseases (common), Nephrological diseases

Aliases & Classifications for Steroid-Resistant Nephrotic Syndrome

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Aliases & Descriptions for Steroid-Resistant Nephrotic Syndrome:

Name: Steroid-Resistant Nephrotic Syndrome 23 66
Steroid Resistant Nephrotic Syndrome 23 25
 
Nephrotic Syndrome, Steroid-Resistant, Autosomal Recessive 66
Srn1 23

Classifications:



Summaries for Steroid-Resistant Nephrotic Syndrome

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MalaCards based summary: Steroid-Resistant Nephrotic Syndrome, also known as steroid resistant nephrotic syndrome, is related to familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation and nephrotic syndrome, type 4. An important gene associated with Steroid-Resistant Nephrotic Syndrome is NPHS2 (NPHS2, Podocin), and among its related pathways are Nephrin interactions and Nephrin/Neph1 signaling in the kidney podocyte. Affiliated tissues include testes, kidney and t cells, and related mouse phenotype renal/urinary system.

Related Diseases for Steroid-Resistant Nephrotic Syndrome

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Diseases related to Steroid-Resistant Nephrotic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation33.3CD2AP, NPHS2
2nephrotic syndrome, type 429.0CD2AP, NPHS1, NPHS2, WT1
3sporadic idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis12.3
4familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis12.3
5sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation12.3
6sporadic idiopathic steroid-resistant nephrotic syndrome with minimal changes12.3
7sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis12.3
8familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis12.3
9familial idiopathic steroid-resistant nephrotic syndrome with minimal changes12.3
10sporadic idiopathic steroid-resistant nephrotic syndrome with collapsing glomerulopathy12.3
11focal segmental glomerulosclerosis11.6
12nephrotic syndrome, type 211.6
13nephrotic syndrome, idiopathic, steroid-resistant11.6
14coenzyme q10 deficiency, primary, 611.4
15glomerulosclerosis, focal segmental, 411.3
16nephrotic syndrome11.1
17glomerulosclerosis10.4
18nephrotic syndrome, type 110.3
19pfeiffer syndrome type 210.2NPHS1, NPHS2
20hypothyroidism10.1
21pfeiffer syndrome type 310.1NPHS1, WT1
22encephalopathy10.0
23hypopigmentation of eyelid10.0NPHS1, NPHS2
24systemic lupus erythematosus9.9
25membranous nephropathy9.9
26multiple myeloma9.9
27galloway-mowat syndrome9.9
28glomerulonephritis9.9
29myeloma9.9
30microcephaly9.9
31hemolytic-uremic syndrome9.9
32anuria9.9
33food allergy9.9
34thymoma9.9
35cerebritis9.9
36sagittal sinus thrombosis9.9
37proliferative glomerulonephritis9.9
38mesangial proliferative glomerulonephritis9.9
39lymphopenia9.9
40thyroiditis9.9
41peritonitis9.9
42lupus erythematosus9.9
43meningitis9.9
44c1q nephropathy9.9
45dense deposit disease9.9
46corneal dystrophy, fuchs endothelial, 89.9NPHS1, NPHS2
47agammaglobulinemia 69.8ALB, NPHS1
48brachyolmia9.8ALB, WT1
49acute myeloid leukemia with cebpa somatic mutations9.7CD2AP, NPHS1
50muscular dystrophy-dystroglycanopathy , type a, 19.7CD2AP, NPHS2

Graphical network of the top 20 diseases related to Steroid-Resistant Nephrotic Syndrome:



Diseases related to steroid-resistant nephrotic syndrome

Symptoms for Steroid-Resistant Nephrotic Syndrome

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Drugs & Therapeutics for Steroid-Resistant Nephrotic Syndrome

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Drugs for Steroid-Resistant Nephrotic Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TacrolimusPhase 41058104987-11-3445643, 439492
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
Anhydrous tacrolimus
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
 
FR900506
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus anhydrous
Tacrolimus hydrate
Tacrolimus, anhydrous
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
2
rituximabPhase 4, Phase 2, Phase 31611174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
3
IrbesartanPhase 299138402-11-63749
Synonyms:
138402-11-6
2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one
2-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one
2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-[ p -( o -1 H -tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4,4]non-1-en-4-one
2-butyl-3-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[
2-butyl-3-[2'-(1h-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[
2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-n-butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one
8-butyl-7-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-7,9-diazaspiro[4.4]non-8-en-6-one
AC-537
AC1L1GMK
Aprovel
Avalide
Avapro
Avapro (TN)
BIDD:GT0347
BMS 186295
BMS Brand of Irbesartan
BMS-186295
BMS-186295, SR-47436, Aprovel, Karvea, Irbesartan
BRD-K60038276-001-02-5
BSPBio_002687
Bio-0053
Bristol Myers Brand of Irbesartan
C07469
C081309
C25H28N6O
CHEBI:5959
CHEMBL1513
CID3749
CPD000466306
D00523
DB01029
HMS1922J05
HMS2051L08
HMS2093E16
 
I06-0690
Irbesarran
Irbesartan
Irbesartan (JAN/USAN/INN)
Irbesartan [USAN:INN]
Irbesartan [Usan:Inn]
Irbetan
Jsp002315
KBio2_002231
KBio2_004799
KBio2_007367
KBio3_001907
KBioGR_001603
KBioSS_002231
Karvea
L000319
LS-60064
Lrbesartan
MLS000759408
MLS001424099
MolPort-003-666-550
NCGC00095122-01
NCGC00095122-02
NCGC00095122-03
S1507_Selleck
SAM001246548
SMR000466306
SPBio_001889
SPECTRUM1504259
SR 47436
SR-47436
STK645362
Sanofi Winthrop Brand of Irbesartan
Spectrum2_001675
Spectrum3_000994
Spectrum4_001122
Spectrum5_001288
Spectrum_001751
TL8000875
UNII-J0E2756Z7N
irbesartan
4
angiotensin IIPhase 2113568521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
5vitamin d1607
6
CholecalciferolNutraceutical82667-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
7
ErgocalciferolNutraceutical121150-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Resistant Nephrotic SyndromeRecruitingNCT02382575Phase 4
2Therapeutic Effect of Tacrolimus on Primary Nephrotic Syndrome in ChildrenWithdrawnNCT01162005Phase 4
3Rituximab Trial for Pediatric Nephrotic SyndromeRecruitingNCT01716442Phase 2, Phase 3
4Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental GlomerulosclerosisActive, not recruitingNCT01613118Phase 2
5Oral Galactose in Children With Steroid Resistant Nephrotic SyndromeCompletedNCT01113385
6Angiotensin Converting Enzyme Gene Polymorphism in Children With Idiopathic Nephrotic SyndromeCompletedNCT00172276
7Vitamin D Supplementation in Glomerular DiseaseRecruitingNCT01835639
8Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental GlomerulosclerosisTerminatedNCT00883636

Search NIH Clinical Center for Steroid-Resistant Nephrotic Syndrome

Genetic Tests for Steroid-Resistant Nephrotic Syndrome

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Genetic tests related to Steroid-Resistant Nephrotic Syndrome:

id Genetic test Affiliating Genes
1 Steroid-Resistant Nephrotic Syndrome25 23 NPHS2

Anatomical Context for Steroid-Resistant Nephrotic Syndrome

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MalaCards organs/tissues related to Steroid-Resistant Nephrotic Syndrome:

34
Testes, Kidney, T cells, Thyroid, Heart

Animal Models for Steroid-Resistant Nephrotic Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Steroid-Resistant Nephrotic Syndrome:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.7ALB, CD2AP, NPHS1, NPHS2, WT1

Publications for Steroid-Resistant Nephrotic Syndrome

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Articles related to Steroid-Resistant Nephrotic Syndrome:

(show top 50)    (show all 275)
idTitleAuthorsYear
1
Patterns of Childhood Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome in Saudi Children: Clinicopathological Study of 87 Cases. (27130200)
2016
2
Lessons from genetics: is it time to revise the therapeutic approach to children with steroid-resistant nephrotic syndrome? (27209298)
2016
3
Comparison of Efficacy of Tacrolimus Versus Cyclosporine in Childhood Steroid-Resistant Nephrotic Syndrome. (27504551)
2016
4
Defects of CRB2 cause steroid-resistant nephrotic syndrome. (25557779)
2015
5
Clinical efficacy and pharmacokinetics of tacrolimus in children with steroid-resistant nephrotic syndrome. (26135137)
2015
6
NPHS2 Mutations in Steroid-Resistant Nephrotic Syndrome: A Mutation Update and the Associated Phenotypic Spectrum. (24227627)
2014
7
Steroid-resistant nephrotic syndrome secondary to primary focal segmental glomerulosclerosis and smoldering multiple myeloma. (24381395)
2014
8
The p.R229Q variant of the NPHS2 (podocin) gene in focal segmental glomerulosclerosis and steroid-resistant nephrotic syndrome: a meta-analysis. (24715228)
2014
9
R: Histological patterns of idiopathic steroid resistant nephrotic syndrome in Egyptian children: A single centre study. (24475443)
2013
10
A large intracardiac thrombus in a child with steroid-resistant nephrotic syndrome. (22813602)
2013
11
Steroid-resistant nephrotic syndrome: impact of genetic testing. (24413855)
2013
12
Immunosupressive therapy in children with steroid-resistant nephrotic syndrome: single center experience. (24100739)
2013
13
Calcineurin inhibitor induced nephrotoxicity in steroid resistant nephrotic syndrome. (23580804)
2013
14
NPHS2 mutations in Indian children with sporadic early steroid resistant nephrotic syndrome. (22080622)
2012
15
Steroid-resistant nephrotic syndrome associated with steroid sulfatase deficiency-x-linked recessive ichthyosis: a case report and review of literature. (22419362)
2012
16
Combined renin angiotensin blockade in childhood steroid-resistant nephrotic syndrome. (22621380)
2012
17
Histopathological spectrum of childhood idiopathic steroid-resistant nephrotic syndrome in Tunisia. (21387228)
2011
18
Novel mutations in steroid-resistant nephrotic syndrome diagnosed in Tunisian children. (21125408)
2011
19
Clinical value of NPHS2 analysis in early- and adult-onset steroid-resistant nephrotic syndrome. (20947785)
2011
20
Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation. (21171529)
2010
21
Long-term outcome of children with steroid-resistant nephrotic syndrome treated with tacrolimus. (20217433)
2010
22
Successful use of single-dose rituximab for the maintenance of remission in a patient with steroid-resistant nephrotic syndrome. (19881243)
2009
23
Experience with tacrolimus in children with steroid-resistant nephrotic syndrome. (19499248)
2009
24
Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant. (19145239)
2009
25
Cyclosporine and steroid therapy in children with steroid-resistant nephrotic syndrome. (19714370)
2009
26
Genetic variations of NPHS2 and WT1 genes in 15 Chinese children with sporadic steroid-resistant nephrotic syndrome]. (19573440)
2009
27
SMARCAL1 mutations: a cause of prepubertal idiopathic steroid-resistant nephrotic syndrome. (19127206)
2009
28
Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome-a randomized controlled multicentre trial by the Arbeitsgemeinschaft fA1r PAodiatrische Nephrologie. (18481113)
2008
29
Steroid-resistant nephrotic syndrome. (18596732)
2008
30
Tacrolimus: a new therapy for steroid-resistant nephrotic syndrome in children. (18039644)
2008
31
The clinical effectiveness and cost-effectiveness of treatments for children with idiopathic steroid-resistant nephrotic syndrome: a systematic review. (17537341)
2007
32
Treatment of steroid-resistant nephrotic syndrome with cyclosporine: study of 17 cases and a literature review. (16358229)
2005
33
Mutations in NPHS2 in sporadic steroid-resistant nephrotic syndrome in Chinese children. (15769810)
2005
34
Steroid-resistant nephrotic syndrome and NPHS2 gene]. (15833180)
2005
35
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
36
NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence. (15253708)
2004
37
Three siblings with steroid-resistant nephrotic syndrome: new NPHS2 mutations in a Turkish family. (15264208)
2004
38
Cyclosporine in patients with steroid-resistant nephrotic syndrome: an open-label, nonrandomized, retrospective study. (15531003)
2004
39
Short term efficacy of intravenous dexamethasone and methylprednisolone therapy in steroid resistant nephrotic syndrome. (15523124)
2004
40
A gene locus for steroid-resistant nephrotic syndrome with deafness maps to chromosome 14q24.2. (12761252)
2003
41
Not all in the family: mutations of podocin in sporadic steroid-resistant nephrotic syndrome. (11805190)
2002
42
Pulse methylprednisolone treatment of idiopathic steroid-resistant nephrotic syndrome. (11322372)
2001
43
Steroid-resistant nephrotic syndrome at 4 months: no complications over 10 years. (10872200)
2000
44
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. (10742096)
2000
45
Successful management of steroid-resistant nephrotic syndrome using ibuprofen. (9021245)
1997
46
Steroid-resistant nephrotic syndrome associated with malignant thymoma. (8953125)
1996
47
Presymptomatic diagnosis of familial steroid-resistant nephrotic syndrome. (8606597)
1996
48
Neurotoxicity of Cyclosporine A in therapy of steroid resistant nephrotic syndrome in a 10-year old boy. (8711194)
1996
49
Steroid resistant nephrotic syndrome associated with spondyloepiphyseal dysplasia, transient ischemic attacks and lymphopenia. (7736684)
1995
50
Inefficacy and toxicity of pefloxacin in focal and segmental glomerulosclerosis with steroid-resistant nephrotic syndrome. (8099164)
1993

Variations for Steroid-Resistant Nephrotic Syndrome

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Expression for genes affiliated with Steroid-Resistant Nephrotic Syndrome

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Search GEO for disease gene expression data for Steroid-Resistant Nephrotic Syndrome.

Pathways for genes affiliated with Steroid-Resistant Nephrotic Syndrome

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Pathways related to Steroid-Resistant Nephrotic Syndrome according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1CD2AP, NPHS1
28.2CD2AP, NPHS1, NPHS2, TRPC6

GO Terms for genes affiliated with Steroid-Resistant Nephrotic Syndrome

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Cellular components related to Steroid-Resistant Nephrotic Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1slit diaphragmGO:00360579.6NPHS1, NPHS2, TRPC6
2protein complexGO:00432348.7ALB, CD2AP, NPHS2

Biological processes related to Steroid-Resistant Nephrotic Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glomerular basement membrane developmentGO:00328369.5NPHS1, WT1
2excretionGO:00075889.5NPHS1, NPHS2

Sources for Steroid-Resistant Nephrotic Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet