MCID: STR044
MIFTS: 38

Steroid-Resistant Nephrotic Syndrome malady

Categories: Genetic diseases (common), Nephrological diseases

Aliases & Classifications for Steroid-Resistant Nephrotic Syndrome

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Aliases & Descriptions for Steroid-Resistant Nephrotic Syndrome:

Name: Steroid-Resistant Nephrotic Syndrome 24 68
Steroid Resistant Nephrotic Syndrome 24 27
Nephrotic Syndrome, Steroid-Resistant, Autosomal Recessive 68
 
Steroid Resistant Nephrotic Syndrome of Childhood 68
Srn1 24

Classifications:



Summaries for Steroid-Resistant Nephrotic Syndrome

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MalaCards based summary: Steroid-Resistant Nephrotic Syndrome, also known as steroid resistant nephrotic syndrome, is related to familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation and nephrotic syndrome, type 4. An important gene associated with Steroid-Resistant Nephrotic Syndrome is NPHS2 (NPHS2, Podocin), and among its related pathways are Nephrin/Neph1 signaling in the kidney podocyte and Cell junction organization. Affiliated tissues include testes, bone and kidney, and related mouse phenotypes are homeostasis/metabolism and mortality/aging.

Related Diseases for Steroid-Resistant Nephrotic Syndrome

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Diseases related to Steroid-Resistant Nephrotic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 61)
idRelated DiseaseScoreTop Affiliating Genes
1familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation33.4CD2AP, NPHS2
2nephrotic syndrome, type 430.8CD2AP, NPHS1, NPHS2, WT1
3sporadic idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis12.2
4familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis12.2
5sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation12.2
6sporadic idiopathic steroid-resistant nephrotic syndrome with minimal changes12.2
7sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis12.2
8familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis12.2
9familial idiopathic steroid-resistant nephrotic syndrome with minimal changes12.2
10sporadic idiopathic steroid-resistant nephrotic syndrome with collapsing glomerulopathy12.2
11nephrotic syndrome, type 211.8
12focal segmental glomerulosclerosis11.6
13nephrotic syndrome, idiopathic, steroid-resistant11.4
14coenzyme q10 deficiency, primary, 611.3
15nephrotic syndrome, type 111.2
16glomerulosclerosis, focal segmental, 411.1
17glomerulosclerosis10.3
18pfeiffer syndrome type 210.1NPHS1, NPHS2
19hypothyroidism10.0
20pfeiffer syndrome type 310.0NPHS1, WT1
21muscular dystrophy-dystroglycanopathy , type a, 19.9CD2AP, NPHS2
22membranous nephropathy9.9
23encephalopathy9.9
24acute myeloid leukemia with cebpa somatic mutations9.9CD2AP, NPHS1
25systemic lupus erythematosus9.8
26multiple myeloma9.8
27galloway-mowat syndrome9.8
28glomerulonephritis9.8
29microcephaly9.8
30hemolytic-uremic syndrome9.8
31anuria9.8
32food allergy9.8
33thymoma9.8
34cerebritis9.8
35sagittal sinus thrombosis9.8
36proliferative glomerulonephritis9.8
37mesangial proliferative glomerulonephritis9.8
38lymphopenia9.8
39thyroiditis9.8
40peritonitis9.8
41lupus erythematosus9.8
42meningitis9.8
43c1q nephropathy9.8
44dense deposit disease9.8
45hypopigmentation of eyelid9.7NPHS1, NPHS2
46agammaglobulinemia 69.6ALB, NPHS1
47stomatitis9.6ALB, NPHS1, NPHS2
48granuloma annulare9.5ALB, NPHS1, NPHS2
49corneal dystrophy, fuchs endothelial, 89.4ACTN4, NPHS1, NPHS2
50coronary thrombosis9.4NPHS1, NPHS2, NUP205, WT1

Graphical network of the top 20 diseases related to Steroid-Resistant Nephrotic Syndrome:



Diseases related to steroid-resistant nephrotic syndrome

Symptoms & Phenotypes for Steroid-Resistant Nephrotic Syndrome

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MGI Mouse Phenotypes related to Steroid-Resistant Nephrotic Syndrome according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.0ACTN4, ALB, CD2AP, NPHS1, NPHS2, WT1
2MP:00107687.9ACTN4, ALB, CD2AP, NPHS1, NPHS2, WT1
3MP:00053677.2ACTN4, ALB, CD2AP, NPHS1, NPHS2, WT1

Drugs & Therapeutics for Steroid-Resistant Nephrotic Syndrome

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Drugs for Steroid-Resistant Nephrotic Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 32)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
rituximabapprovedPhase 4, Phase 2, Phase 31654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
2
Tacrolimusapproved, investigationalPhase 41074104987-11-3445643, 439492
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
Anhydrous tacrolimus
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
 
FR900506
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus anhydrous
Tacrolimus hydrate
Tacrolimus, anhydrous
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
3Antirheumatic AgentsPhase 4, Phase 2, Phase 310627
4Immunosuppressive AgentsPhase 412770
5Calcineurin InhibitorsPhase 41597
6ImmunoglobulinsPhase 46045
7AntibodiesPhase 46045
8
Irbesartanapproved, investigationalPhase 2101138402-11-63749
Synonyms:
138402-11-6
2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one
2-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one
2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-[ p -( o -1 H -tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4,4]non-1-en-4-one
2-butyl-3-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[
2-butyl-3-[2'-(1h-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[
2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-n-butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one
8-butyl-7-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-7,9-diazaspiro[4.4]non-8-en-6-one
AC-537
AC1L1GMK
Aprovel
Avalide
Avapro
Avapro (TN)
BIDD:GT0347
BMS 186295
BMS Brand of Irbesartan
BMS-186295
BMS-186295, SR-47436, Aprovel, Karvea, Irbesartan
BRD-K60038276-001-02-5
BSPBio_002687
Bio-0053
Bristol Myers Brand of Irbesartan
C07469
C081309
C25H28N6O
CHEBI:5959
CHEMBL1513
CID3749
CPD000466306
D00523
DB01029
HMS1922J05
HMS2051L08
HMS2093E16
 
I06-0690
Irbesarran
Irbesartan
Irbesartan (JAN/USAN/INN)
Irbesartan [USAN:INN]
Irbesartan [Usan:Inn]
Irbetan
Jsp002315
KBio2_002231
KBio2_004799
KBio2_007367
KBio3_001907
KBioGR_001603
KBioSS_002231
Karvea
L000319
LS-60064
Lrbesartan
MLS000759408
MLS001424099
MolPort-003-666-550
NCGC00095122-01
NCGC00095122-02
NCGC00095122-03
S1507_Selleck
SAM001246548
SMR000466306
SPBio_001889
SPECTRUM1504259
SR 47436
SR-47436
STK645362
Sanofi Winthrop Brand of Irbesartan
Spectrum2_001675
Spectrum3_000994
Spectrum4_001122
Spectrum5_001288
Spectrum_001751
TL8000875
UNII-J0E2756Z7N
irbesartan
9Antihypertensive AgentsPhase 24095
10AngiotensinogenPhase 21161
11
Angiotensin IIPhase 2116268521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
12Angiotensin Receptor AntagonistsPhase 21173
13Angiotensin II Type 1 Receptor BlockersPhase 21078
14
Ergocalciferolapproved, nutraceutical123250-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
15
Cholecalciferolapproved, nutraceutical85167-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
16Hormone Antagonists12778
17Endorphins65
18beta-endorphin133
19Hormones13979
20Hormones, Hormone Substitutes, and Hormone Antagonists12767
21Neurotransmitter Agents17734
22Melanocyte-Stimulating Hormones132
23Adrenocorticotropic Hormone155
24Vitamins5095
25Immunoglobulin A118
26Ergocalciferols1232
27Bone Density Conservation Agents3266
28Micronutrients5802
29Trace Elements5802
30vitamin d1653
31Vitamin D2Nutraceutical1232
32CalciferolNutraceutical1334

Interventional clinical trials:

idNameStatusNCT IDPhase
1Therapeutic Effect of Tacrolimus on Primary Nephrotic Syndrome in ChildrenCompletedNCT01162005Phase 4
2Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Resistant Nephrotic SyndromeRecruitingNCT02382575Phase 4
3Rituximab Trial for Pediatric Nephrotic SyndromeUnknown statusNCT01716442Phase 2, Phase 3
4Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental GlomerulosclerosisActive, not recruitingNCT01613118Phase 2
5Oral Galactose in Children With Steroid Resistant Nephrotic SyndromeCompletedNCT01113385
6Angiotensin Converting Enzyme Gene Polymorphism in Children With Idiopathic Nephrotic SyndromeCompletedNCT00172276
7Vitamin D Supplementation in Glomerular DiseaseRecruitingNCT01835639
8Availability Study of ACTH to Treat Children SRNS/SDNSRecruitingNCT02972346
9Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental GlomerulosclerosisTerminatedNCT00883636

Search NIH Clinical Center for Steroid-Resistant Nephrotic Syndrome

Genetic Tests for Steroid-Resistant Nephrotic Syndrome

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Genetic tests related to Steroid-Resistant Nephrotic Syndrome:

id Genetic test Affiliating Genes
1 Steroid-Resistant Nephrotic Syndrome27 24 NPHS2

Anatomical Context for Steroid-Resistant Nephrotic Syndrome

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MalaCards organs/tissues related to Steroid-Resistant Nephrotic Syndrome:

36
Testes, Bone, Kidney, T cells, Heart, Thyroid

Publications for Steroid-Resistant Nephrotic Syndrome

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Articles related to Steroid-Resistant Nephrotic Syndrome:

(show top 50)    (show all 284)
idTitleAuthorsYear
1
Further phenotypic heterogeneity of CoQ10 deficiency associated with Steroid Resistant Nephrotic Syndrome and novel COQ2 and COQ6 variants. (28044327)
2017
2
Screening of WT1 mutations in exon 8 and 9 in children with steroid resistant nephrotic syndrome from a single centre and establishment of a rapid screening assay using high-resolution melting analysis in a clinical setting. (28068926)
2017
3
Wilms' tumour 1 gene mutations in south Indian children with steroid-resistant nephrotic syndrome. (27934809)
2016
4
Patterns of Childhood Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome in Saudi Children: Clinicopathological Study of 87 Cases. (27130200)
2016
5
Lessons from genetics: is it time to revise the therapeutic approach to children with steroid-resistant nephrotic syndrome? (27209298)
2016
6
Comparison of Efficacy of Tacrolimus Versus Cyclosporine in Childhood Steroid-Resistant Nephrotic Syndrome. (27504551)
2016
7
Novel NPHS2 variant in patients with familial steroid-resistant nephrotic syndrome with early onset, slow progression and dominant inheritance pattern. (27573339)
2016
8
NUP107 mutations in children with steroid-resistant nephrotic syndrome. (27190346)
2016
9
Altered expression of Crb2 in podocytes expands a variation of CRB2 mutations in steroid-resistant nephrotic syndrome. (27942854)
2016
10
Pneumococcal hemolytic uremic syndrome and steroid resistant nephrotic syndrome. (27478599)
2016
11
Children with Steroid-resistant Nephrotic Syndrome: Long-term Outcomes of Sequential Steroid Therapy. (27806747)
2016
12
Steroid-resistant nephrotic syndrome caused by novel WT1 mutation inherited from a mosaic parent. (26627896)
2016
13
Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome. (26878725)
2016
14
Efficacy of rituximab therapy against intractable steroid-resistant nephrotic syndrome. (26865241)
2016
15
Rapid Response to Cyclosporin A and Favorable Renal Outcome in Nongenetic Versus Genetic Steroid-Resistant Nephrotic Syndrome. (26668027)
2016
16
Proteomics Approach Identifies Factors Associated With the Response to Low-Density Lipoprotein Apheresis Therapy in Patients With Steroid-Resistant Nephrotic Syndrome. (26771065)
2016
17
Corrigendum: Analysis of the genes responsible for steroid-resistant nephrotic syndrome and/or focal segmental glomerulosclerosis in Japanese patients by whole-exome sequencing analysis. (27557799)
2016
18
P-Glycoprotein Activity in Steroid-Responsive vs. Steroid-Resistant Nephrotic Syndrome. (27193461)
2016
19
WT1 and NPHS2 gene mutation analysis and clinical management of steroid-resistant nephrotic syndrome. (27885584)
2016
20
Interventions for idiopathic steroid-resistant nephrotic syndrome in children. (27726125)
2016
21
Mizoribine therapy combined with steroids and mizoribine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome. (27783276)
2016
22
Steroid-resistant nephrotic syndrome: a persistent challenge for pediatric nephrology. (27783158)
2016
23
A 17-Year-Old With Steroid-Resistant Nephrotic Syndrome. (27244796)
2016
24
Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome. (26792978)
2016
25
Mutations in WT1 in boys with sporadic isolated steroid-resistant nephrotic syndrome. (26985958)
2016
26
Long-term outcome of idiopathic steroid-resistant nephrotic syndrome in children: response to comments. (26628279)
2016
27
Defects of CRB2 cause steroid-resistant nephrotic syndrome. (25557779)
2015
28
Clinical efficacy and pharmacokinetics of tacrolimus in children with steroid-resistant nephrotic syndrome. (26135137)
2015
29
Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome. (26411495)
2015
30
Use of Cyclosporine Therapy in Steroid Resistant Nephrotic Syndrome (SRNS): A Review. (26573045)
2015
31
Iodine-induced non-autoimmune hypothyroidism in a patient with steroid-resistant nephrotic syndrome. (26508200)
2015
32
Mycophenolate Mofetil Following Rituximab in Children With Steroid-Resistant Nephrotic Syndrome. (26101364)
2015
33
Analysis of the genes responsible for steroid-resistant nephrotic syndrome and/or focal segmental glomerulosclerosis in Japanese patients by whole-exome sequencing analysis. (26467726)
2015
34
A genetic study of steroid-resistant nephrotic syndrome: relationship between polymorphism -173 G to C in the MIF gene and serum level MIF in children. (26541175)
2015
35
From microscopy to molecules: unraveling the pathogenesis of steroid-resistant nephrotic syndrome. (25899183)
2015
36
Long-Term Outcomes in Children with Steroid-Resistant Nephrotic Syndrome Treated with Calcineurin Inhibitors. (26640779)
2015
37
Response to cyclosporine in steroid-resistant nephrotic syndrome: discontinuation is possible. (25903641)
2015
38
Evaluation of Thyroid Hormone Status in Children with Steroid Resistant Nephrotic Syndrome: A North India Study. (26420548)
2015
39
Steroid Resistant Nephrotic Syndrome-Genetic Consideration. (27442391)
2015
40
Rituximab treatment for refractory steroid-resistant nephrotic syndrome. (26386588)
2015
41
Meningitis and intracranial bleed in a child with steroid-resistant nephrotic syndrome. (26586071)
2015
42
TACROLIMUS DRUG LEVEL AND RESPONSE TO TREATMENT IN IDIOPATHIC CHILDHOOD STEROID RESISTANT NEPHROTIC SYNDROME. (27004322)
2015
43
HISTOPATHOLOGICAL PATTERNS IN PAEDIATRIC IDIOPATHIC STEROID RESISTANT NEPHROTIC SYNDROME. (26721026)
2015
44
Long-term outcome of idiopathic steroid-resistant nephrotic syndrome in children. (26335197)
2015
45
In silico analysis of functional nsSNPs in human TRPC6 gene associated with steroid resistant nephrotic syndrome. (26127002)
2015
46
Favorable outcome in children with idiopathic steroid-resistant nephrotic syndrome due to mesangial hypercellularity: A distinct disease entity? (26493069)
2015
47
Genetic testing in steroid-resistant nephrotic syndrome: when and how? (26507970)
2015
48
NPHS2 Mutations in Steroid-Resistant Nephrotic Syndrome: A Mutation Update and the Associated Phenotypic Spectrum. (24227627)
2014
49
Steroid-resistant nephrotic syndrome secondary to primary focal segmental glomerulosclerosis and smoldering multiple myeloma. (24381395)
2014
50
The p.R229Q variant of the NPHS2 (podocin) gene in focal segmental glomerulosclerosis and steroid-resistant nephrotic syndrome: a meta-analysis. (24715228)
2014

Variations for Steroid-Resistant Nephrotic Syndrome

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Clinvar genetic disease variations for Steroid-Resistant Nephrotic Syndrome:

5
id Gene Variation Type Significance SNP ID Assembly Location
1NPHS2NM_014625.3(NPHS2): c.413G> A (p.Arg138Gln)SNVPathogenicrs74315342GRCh37Chr 1, 179530462: 179530462

Expression for genes affiliated with Steroid-Resistant Nephrotic Syndrome

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Search GEO for disease gene expression data for Steroid-Resistant Nephrotic Syndrome.

Pathways for genes affiliated with Steroid-Resistant Nephrotic Syndrome

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GO Terms for genes affiliated with Steroid-Resistant Nephrotic Syndrome

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Cellular components related to Steroid-Resistant Nephrotic Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.7ACTN4, ALB
2slit diaphragmGO:00360579.6NPHS1, NPHS2
3cell-cell junctionGO:00059119.5ACTN4, CD2AP, NPHS2
4protein complexGO:00432348.3ACTN4, ALB, CD2AP, NPHS2
5extracellular exosomeGO:00700628.3ACTN4, ALB, CD2AP, NPHS1, NPHS2

Biological processes related to Steroid-Resistant Nephrotic Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1excretionGO:000758810.1NPHS1, NPHS2
2glomerular basement membrane developmentGO:003283610.0NPHS1, WT1
3platelet degranulationGO:00025769.0ACTN4, ALB

Sources for Steroid-Resistant Nephrotic Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet