MCID: STM004
MIFTS: 65

Stomach Cancer malady

Cancer diseases, Gastrointestinal diseases categories

Summaries for Stomach Cancer

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Sources:
8Disease Ontology, 33MedlinePlus, 63Wikipedia, 46OMIM, 32MalaCards
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MedlinePlus:33 The stomach is an organ between the esophagus and the small intestine. it mixes food with stomach acid and helps digest protein. stomach cancer mostly affects older people - two-thirds of people who have it are over age 65. your risk of getting it is also higher if you have had a helicobacter pylori infection have had stomach inflammation are a man eat lots of salted, smoked, or pickled foods smoke cigarettes have a family history of stomach cancer it is hard to diagnose stomach cancer in its early stages. indigestion and stomach discomfort can be symptoms of early cancer, but other problems can cause the same symptoms. in advanced cases, there may be blood in your stool, vomiting, unexplained weight loss, jaundice, or trouble swallowing. doctors diagnose stomach cancer with a physical exam, blood and imaging tests, an endoscopy, and a biopsy. because it is often found late, it can be hard to treat stomach cancer. treatment options include surgery, chemotherapy, radiation or a combination. nih: national cancer institute

MalaCards: Stomach Cancer, also known as stomach carcinoma, is related to adenocarcinoma and pancreatic cancer. An important gene associated with Stomach Cancer is MUTYH (mutY homolog). The drugs cisplatin and cisplatin pwdr have been mentioned in the context of this disorder. Affiliated tissues include the stomach, testes and small intestine.

Disease Ontology:8 A gastrointestinal system cancer that is located in the stomach.

Wikipedia:63 Stomach cancer, or gastric cancer, refers to cancer arising from any part of the stomach. Stomach cancer... more...

Description from OMIM:46 613659,137215

Aliases & Classifications for Stomach Cancer

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 33MedlinePlus, 60UMLS, 22GTR, 44Novoseek, 56SNOMED-CT, 34MeSH, 27ICD9CM, 39NCIt, 46OMIM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

stomach cancer 8 42 10 33
stomach carcinoma 8 42 60
malignant tumor of greater curve of stomach 8 60
malignant tumor of lesser curve of stomach 8 60
malignant neoplasm of body of stomach 8 60
cancer of the stomach 8 22
gastric carcinoma 8 44
malignant neoplasm of greater curvature of stomach, unspecified 8
malignant neoplasm of lesser curvature of stomach, unspecified 8
malignant neoplasm of greater curve of stomach unspecified 8
malignant neoplasm of lesser curve of stomach unspecified 8
malignant neoplasm of greater curvature of stomach, nos 8
malignant neoplasm of lesser curvature of stomach, nos 8
malignant tumor of body of stomach 8
ca greater curvature of stomach 8
ca greater curvature - stomach 8
ca lesser curvature of stomach 8
ca lesser curvature - stomach 8
malignant neoplasm of stomach 60
adult stomach carcinoma 42
adult stomach cancer 42
carcinoma of stomach 8
neoplasm of stomach 8
ca body - stomach 8
stomach neoplasms 60
stomach neoplasm 8
gastric neoplasm 8
gastric cancer 44


Related Diseases for Stomach Cancer

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Stomach Cancer family:

Stomach Carcinoma in Situ Stomach Cancer, Familial

Diseases related to Stomach Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 313)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma30.2CCKBR, PSCA, CEACAM7
2pancreatic cancer29.9CEACAM7, PSCA, CCKBR
3melanoma29.8CEACAM7, CD70, MAGEA10
4stomach disease10.5
5in situ carcinoma10.5
6breast cancer10.4
7esophageal cancer10.4
8esophagitis10.4
9gastritis10.4
10lung cancer10.4
11disseminated intravascular coagulation10.4
12atrophic gastritis10.3
13colon cancer10.3
14colorectal cancer10.3
15neuroendocrine carcinoma10.3
16lymphoepithelioma-like carcinoma10.3
17retinoblastoma10.3
18cronkhite-canada syndrome10.3
19microinvasive gastric cancer10.3
20situs inversus10.3
21ataxia telangiectasia10.2
22signet ring cell adenocarcinoma10.2
23gastric signet ring cell adenocarcinoma10.2
24li-fraumeni syndrome10.2
25connective tissue cancer10.2
26spleen cancer10.2
27cell type cancer10.2
28gastric adenocarcinoma10.2
29leukemia10.2
30lymph node cancer10.2
31ovarian cancer10.2
32lynch syndrome10.2
33bone carcinoma10.2
34pyloric stenosis10.2
35xeroderma pigmentosum10.2
36intestinal obstruction10.2
37thyroid cancer10.2
38thyroiditis10.2
39gastric ulcer10.2
40pernicious anemia10.2
41peritonitis10.2
42stomach cancer, childhood10.2
43stomach cancer, familial10.2
44small cell carcinoma10.1
45cicatricial pemphigoid10.1
46glomerulonephritis10.1
47gastric tubular adenocarcinoma10.1
48dumping syndrome10.1
49tubular adenocarcinoma10.1
50embryonal cancer10.1

Graphical network of the top 20 diseases related to Stomach Cancer:



Diseases related to stomach cancer

Clinical Features for Stomach Cancer

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Sources:
46OMIM
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Clinical features from OMIM:

613659,137215

Drugs & Therapeutics for Stomach Cancer

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Stomach Cancer

Drug clinical trials:

Search ClinicalTrials for Stomach Cancer

Search NIH Clinical Center for Stomach Cancer

Search CenterWatch for Stomach Cancer

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Stomach Cancer

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Sources:
22GTR
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Genetic tests related to Stomach Cancer:

id Genetic test Affiliating Genes
1 Neoplasm of Stomach22

Anatomical Context for Stomach Cancer

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Stomach Cancer:

32
Testes, Small intestine, Breast, Colon, Lung, Liver, Lymph node, Bone, Pancreas, Prostate, Bone marrow, Endothelial, Kidney, Thyroid, Heart, Brain, Cervix

FMA organs/tissues related to Stomach Cancer:

14
The stomach

Animal Models for Stomach Cancer or affiliated genes

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Publications for Stomach Cancer

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Sources:
50PubMed
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Articles related to Stomach Cancer:

(show top 50)    (show all 626)
idTitleAuthorsYear
1
Stomach cancer risk after treatment for hodgkin lymphoma. (23980092)
2013
2
Trends in oesophagus and Stomach cancer incidence in Bangalore, India. (23339980)
2013
3
Preoperative N staging of gastric cancer by stomach protocol computed tomography. (24156034)
2013
4
Induction of chromosome instability and stomach cancer by altering the expression pattern of mitotic checkpoint genes in mice exposed to areca-nut. (23805780)
2013
5
Stomach metastasis in a patient with prostate cancer 4 years after the initial diagnosis: a case report and a literature review. (23243531)
2012
6
Association of CASP3 and CASP9 polymorphisms with genetic susceptibility to stomach cancer]. (21644232)
2011
7
Incidence of stomach cancer in oman and the other gulf cooperation council countries. (22043430)
2011
8
Colonoscopy screening for individuals aged 40-49 years with a family history of stomach cancer in Korea. (20012440)
2010
9
Dietary fiber and stomach cancer risk: a case-control study from Italy. (19247788)
2009
10
Prospects of using phytoadaptogen in the treatment of diffuse stomach cancer. (19902104)
2009
11
Impact of supplementary private health insurance on stomach cancer care in Korea: a cross-sectional study. (19643032)
2009
12
Stomach cancer mortality in two large cohorts of migrants from the Former Soviet Union to Israel and Germany: are there implications for prevention? (19242359)
2009
13
Incidence and survival of stomach cancer in a high-risk population of Chile. (19370783)
2009
14
Interleukin-18 increases metastasis and immune escape of stomach cancer via the downregulation of CD70 and maintenance of CD44. (19638429)
2009
15
Review of salt consumption and stomach cancer risk: epidemiological and biological evidence. (19437559)
2009
16
Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells. (19020714)
2008
17
Laparoscopic ultrasonography-assisted retroperitoneal lymph node sampling in patients evaluated for stomach cancer recurrence. (18645082)
2008
18
Overexpression of phospholipase D suppresses taxotere-induced cell death in stomach cancer cells. (18190795)
2008
19
Stomach cancer-derived del223V-226L mutation of the STCH gene causes loss of sensitization to TRAIL-mediated apoptosis. (18793616)
2008
20
Stomach cancer. (19445803)
2008
21
Self-reported experience and outcomes of care among stomach cancer patients at a median follow-up time of 27 months from diagnosis. (17909862)
2008
22
Alpha-fetoprotein-producing early gastric cancer of the remnant stomach: report of a case. (17952534)
2007
23
The expression of thymidine phosphorylase in cancer-infiltrating inflammatory cells in stomach cancer. (17923735)
2007
24
A nested case-control study of stomach cancer and serum insulin-like growth factor (IGF)-1, IGF-2 and IGF-binding protein (IGFBP)-3. (17532620)
2007
25
Self-expanding metallic stents for gastric outlet obstruction resulting from stomach cancer: a preliminary study with a newly designed double-layered pyloric stent. (18028923)
2007
26
Stomach cancer. (16973033)
2006
27
Processed meat consumption and stomach cancer risk: a meta-analysis. (16882945)
2006
28
Stomach cancer. (16520108)
2006
29
Helicobacter pylori infection appears the prime risk factor for stomach cancer. (17016826)
2006
30
Bone marrow cells as the origin of stomach cancer. (16556065)
2005
31
Francisella tularensis peritonitis in stomach cancer patient. (15663872)
2004
32
Effect of acupressure on nausea and vomiting during chemotherapy cycle for Korean postoperative stomach cancer patients. (15292721)
2004
33
Docetaxel regimen provides survival benefits in advanced stomach cancer patients. (14723011)
2003
34
Population-based study of relationship between hospital surgical volume and 5-year survival of stomach cancer patients in Osaka, Japan. (14611678)
2003
35
Inflammation intersection: gp130 balances gut irritation and stomach cancer. (12357240)
2002
36
Detection of cancer cells in peripheral blood of stomach cancer patients using RT-PCR amplification of tumour-specific mRNAs. (11966534)
2002
37
Study on the Relationship between susceptibility of stomach neoplasm cancer and polymorphism of inducible nitric oxide synthase gene]. (12482371)
2002
38
Dietary factors and stomach cancer mortality. (12085253)
2002
39
RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum. (11135439)
2001
40
Genetic and epigenetic changes in stomach cancer. (11243597)
2001
41
High thoracic midline dorsal column myelotomy for severe visceral pain due to advanced stomach cancer. (10626939)
2000
42
Survival in stomach cancer is improving: results of a nationwide population-based Swedish study. (10450729)
1999
43
Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer. (9895372)
1999
44
By the way, doctor... In your May issue you say that eating medium or well-done beef increases one's risk for stomach cancer. But what about the dangers of eating rare beef? (10066305)
1999
45
Prognostic value of DNA flow cytometry in stomach cancer: a 5-year prospective study. (10206284)
1999
46
Prevention of hepatic metastases by liver lectin blocking with D-galactose in stomach cancer patients. A prospectively randomized clinical trial. (9137507)
1997
47
A case of appendiceal cancer metastatic to the stomach with pseudomyxoma peritonei. (7515309)
1994
48
Intestinal metaplasia, atrophic gastritis and stomach cancer: trends over time. (7735941)
1994
49
An autopsy case of extramural malignant leiomyoblastoma of the stomach with ovarian cancer: an immunohistochemical study]. (2192100)
1990
50
Cell renewal and cancer risk of the stomach: analysis of cell proliferation kinetics in atrophic gastritis. (2637580)
1989

Genetic Variations for Stomach Cancer

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Expression for genes affiliated with Stomach Cancer

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Stomach Cancer

Search GEO for disease gene expression data for Stomach Cancer.

Pathways for genes affiliated with Stomach Cancer

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Compounds for genes affiliated with Stomach Cancer

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GO Terms for genes affiliated with Stomach Cancer

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16Gene Ontology
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Biological processes related to Stomach Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1digestionGO:00758610.7PGA5, PGC, CCKBR

Molecular functions related to Stomach Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1aspartic-type endopeptidase activityGO:00419010.6PGA5, PGC

Products for genes affiliated with Stomach Cancer

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  • Antibodies
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  • Lysates
  • Antibodies

Sources for Stomach Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet