Stomatitis disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

MCID: STM007 MIFTS: 51	Stomatitis malady
2 drugs, 161 genes, 16 tissues, 163 related diseases, clinical trials.

Summaries for Stomatitis

Sources:
⁶³Wikipedia, ³²MalaCards
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Wikipedia:⁶³ Stomatitis is inflammation of the mouth. The term refers to any inflammatory process affecting the... more...

MalaCards: Stomatitis is related to denture stomatitis and ulcerative stomatitis. An important gene associated with Stomatitis is TP63 (tumor protein p63), and among its related pathways are Influenza A and Toll-like receptor signaling pathway. The drugs sucralfate and carbamide peroxide and the compounds serine and rantes have been mentioned in the context of this disorder. Affiliated tissues include t cells, testes and colon, and related mouse phenotype immune system.

Aliases & Classifications for Stomatitis

Sources:
⁸Disease Ontology, ¹⁰DISEASES, ⁴⁴Novoseek, ⁶⁰UMLS, ³⁴MeSH, ⁵⁶SNOMED-CT, ³⁹NCIt
See all sources

Aliases & Descriptions:

stomatitis ⁸ ¹⁰ ⁴⁴ ⁶⁰

External Ids:

Disease Ontology⁸ DOID:9637

MeSH³⁴ D013280

SNOMED-CT⁵⁶ 196527002, 61170000, 95361005 155660009, more

NCIt³⁹ C26887

UMLS⁶⁰ C0038362

Related Diseases for Stomatitis

Sources:
¹⁷GeneCards, ¹⁸GeneDecks
See all sources

Diseases related to Stomatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 163)

id	Related Disease	Score	Top Affiliating Genes
1	denture stomatitis	31.5	CST1, PPP6R1, STATH, ALLC
2	ulcerative stomatitis	31.1	TP63
3	influenza	30.4	IRF3, CD69, CXCR3, MX1, MX2, ERVW-1
4	encephalitis	30.3	MX1, ERVW-1
5	herpes simplex	30.3	IRF3, IRF7, MX1, ERVW-1
6	lichen planus	30.3	CXCR3, MX1
7	hepatitis	30.2	MX1
8	measles	30.1	MX1
9	melanoma	30.1	TNF, IRF3, RNPEP, CXCR3, MX1, CFI
10	hepatitis b	30.0	MX1
11	newcastle disease	30.0	IRF3
12	dermatitis	30.0	CXCR3
13	hepatitis c	29.9	TNF, IRF7, CD69, CXCR3, MX1
14	sarcoma	29.9	TP63, ERVW-1
15	lupus erythematosus	29.9	MX1
16	rabies	29.9	MX1
17	rheumatoid arthritis	29.7	TNF, IRF3, CD69, CXCR3, CFI, ERVW-1
18	arthritis	29.7	MVK, TNF, CD69, CXCR3, MX1
19	psoriasis	29.7	TNF, CD69, CXCR3, MX1
20	multiple sclerosis	29.7	TNF, CD69, CXCR3, MX1, ERVW-1
21	ovarian cancer	29.7	CFI, CD69
22	periodontal disease	29.7	TNF
23	pneumonia	29.7	TNF
24	diarrhea	29.7	ALLC
25	familial mediterranean fever	29.7	TNF, MVK
26	aphthous stomatitis	11.2
27	pharyngitis	10.6
28	cervicitis	10.5
29	cervical adenitis	10.5
30	glossitis	10.3
31	noma	10.2
32	gingivitis	10.2
33	periodic fever, aphthous stomatitis, pharyngitis and adenitis	10.2
34	adenocarcinoma	10.2
35	cheilitis	10.2
36	celiac disease	10.2
37	behcet's disease	10.2
38	vaccinia	10.1
39	pemphigus	10.1
40	neuronitis	10.1
41	adult syndrome	10.1
42	central nervous system disease	10.1
43	nervous system disease	10.1
44	pancreatitis	10.1
45	periodontitis	10.1
46	avian influenza	10.0
47	lymphocytic choriomeningitis	10.0
48	ariboflavinosis	10.0
49	oral candidiasis	10.0
50	hepatitis a	10.0

Graphical network of the top 20 diseases related to Stomatitis:

Clinical Features for Stomatitis

Drugs & Therapeutics for Stomatitis

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶⁰UMLS, ⁴⁰NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Stomatitis

Drug clinical trials:

Search ClinicalTrials for Stomatitis

Search NIH Clinical Center for Stomatitis

Search CenterWatch for Stomatitis

Inferred drug relations via UMLS⁶⁰/NDF-RT⁴⁰:

carbamide peroxide

sucralfate

Genetic Tests for Stomatitis

Anatomical Context for Stomatitis

Sources:
³²MalaCards
See all sources

MalaCards organs/tissues related to Stomatitis:

³²

T cells, Testes, Colon, Brain, Skin, Tongue, Bone, Prostate, Endothelial, Breast, Heart, Monocytes, B cells, Bone marrow, Lung, Tonsil

Animal Models for Stomatitis or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Stomatitis:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system phenotype	MP:0005387	10.8	TP63, MX2, IL12A, CXCR3, CD69, TBK1

Publications for Stomatitis

Sources:
⁵⁰PubMed
See all sources

Articles related to Stomatitis:

(show top 50) (show all 1160)

id	Title	Authors	Year
1	Oxidative stress and recurrent aphthous stomatitis. (24407552)	Bagan J.... Scully C.	2014
2	Newly identified phosphorylation site in the vesicular stomatitis virus p protein is required for viral RNA synthesis. (24257610)	Mondal A.... Wertz G.W.	2014
3	The potential of recombinant vesicular stomatitis virus-mediated virotherapy against metastatic colon cancer. (23232984)	Yamaki M.... Woo S.L.	2013
4	Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (23983059)	Sundqvist M.... Karlsson A.	2013
5	Periodic fever with aphthous stomatitis, pharyngitis, and adenitis responsive to oral corticosteroids and dapsone. (23785712)	Pillemer B.... Gehris R.P.	2013
6	Does the presence of anterior mandibular teeth increase the incidence of denture stomatitis? (22984815)	Sakar O.... Ispirgil E.	2013
7	Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors. (23364315)	Hwang B.Y.... Schaffer D.V.	2013
8	Elucidating role of salivary proteins in denture stomatitis using a proteomic approach. (23041753)	Bencharit S.... Offenbacher S.	2012
9	Treatment with targeted vesicular stomatitis virus generates therapeutic multifunctional anti-tumor memory CD4 T cells. (22240921)	Gao Y.... Bergman I.	2012
10	Full-length genome analysis of vesicular stomatitis New Jersey virus strains representing the phylogenetic and geographic diversity of the virus. (22825698)	Pauszek S.J.... Rodriguez L.L.	2012
11	Microwave denture disinfection versus nystatin in treating patients with well-controlled type 2 diabetes and denture stomatitis: a randomized clinical trial. (22545252)	Sanita P.V.... Vergani C.E.	2012
12	Characterization of the temporal and spatial distribution and reproductive ratio of vesicular stomatitis outbreaks in Mexico in 2008. (21281198)	Arroyo M.... Rodriguez L.L.	2011
13	Association between recurrent aphthous stomatitis and inheritance of a single-nucleotide polymorphism of the NOS2 gene encoding inducible nitric oxide synthase. (21481004)	Karasneh J.A.... Thornhill M.	2011
14	The N(0)-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient I+-helices. (21207454)	Leyrat C.... Jamin M.	2011
15	HIV-protease inhibitors block the replication of both vesicular stomatitis and influenza viruses at an early post-entry replication step. (21620431)	Federico M.	2011
16	The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus. (21795329)	Elsby R.... Barber G.N.	2011
17	Acute necrotic stomatitis (noma) associated with methicillin-resistant Staphylococcus aureus infection in a newly acquired rhesus macaque (Macaca mulatta). (21332756)	Lee J.I.... Kim S.J.	2011
18	In vivo efficacy of alkaline peroxide tablets and mouthwashes on Candida albicans in patients with denture stomatitis. (20857010)	Uludamar A.... Ceyhan I.	2010
19	Susceptibility of breast cancer cells to an oncolytic matrix (M) protein mutant of vesicular stomatitis virus. (20725101)	Ahmed M.... Lyles D.S.	2010
20	Relationship between periodontal parameters and BehAset's disease and evaluation of different treatments for oral recurrent aphthous stomatitis. (19076988)	Arabaci T.... CiAsek Y.	2009
21	Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells. (18846115)	Altomonte J.... Woo S.L.	2009
22	Gluten sensitivity enteropathy in patients with recurrent aphthous stomatitis. (19534771)	Shakeri R.... Shahram F.	2009
23	Allergic contact stomatitis presenting as geographical tongue with pruritus. (19207382)	Waroquier D.... Parent D.	2009
24	Recurrent aphthous stomatitis may be initiated by traumatic epithelial implantation and sustained by localized pathergic status. (17768013)	Aminabadi N.A.	2008
25	Dysfunction of CD4+CD25high T regulatory cells in patients with recurrent aphthous stomatitis. (18318707)	Lewkowicz N.... TchA^rzewski H.	2008
26	Little clinical benefit of early systemic aciclovir for treatment of primary herpetic stomatitis. (19151686)	Porter S.R.	2008
27	Denture stomatitis. (17366680)	Chen A.Y.... Zirwas M.J.	2007
28	Autoimmunity to deltaNp63alpha in chronic ulcerative stomatitis. (17720849)	Solomon L.W.... Kumar V.	2007
29	Characterization of the chicken PKR: polymorphism of the gene and antiviral activity against vesicular stomatitis virus. (15070037)	Ko J.H.... Agui T.	2004
30	An exploration of point, annual, and lifetime prevalence in characterizing recurrent aphthous stomatitis in USA children and youths. (15357677)	Shulman J.D.	2004
31	Recombinant vesicular stomatitis virus vectors as oncolytic agents in the treatment of high-grade gliomas in an organotypic brain tissue slice-glioma coculture model. (15200120)	Duntsch C.D.... Whitt M.A.	2004
32	Chronic ulcerative stomatitis: a case report. (10695945)	Lorenzana E.R.... Detweiler J.G.	2000
33	Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. (10393612)	Padeh S.... Passwell J.H.	1999
34	Miconazole lacquer in the treatment of denture stomatitis: clinical and microbiological findings in Chinese patients. (9552817)	Dias A.P.... Lee M.T.	1997
35	Immunopathogenesis of oral lichen planus and recurrent aphthous stomatitis. (9421220)	Eversole L.R.	1997
36	Recurrent aphthous stomatitis. An update. (8665304)	Ship J.A.	1996
37	Ten cases of chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibody. (1869653)	Beutner E.H.... Kumar V.	1991
38	Clinical evaluation of benzydamine, chlorhexidine, and placebo mouthwashes in the management of recurrent aphthous stomatitis. (3469601)	Matthews R.W.... Hislop W.S.	1987
39	A case report of the successful treatment of recurrent aphthous stomatitis with some preparations of orally administered transfer factor. (6423292)	Schulkind M.L.... Small P.A.	1984
40	Effects of suspected foodstuff challenging agents in the etiology of recurrent aphthous stomatitis. (6956825)	Eversole L.R.... Chambers D.W.	1982
41	Serum beta 2 microglobulin in recurrent aphthous stomatitis and BehAset's syndrome. (6178540)	Scully C.	1982
42	Immunofluorescence microscopic studies of recurrent aphthous stomatitis. (7032425)	VanHale H.M.... Schroeter A.L.	1981
43	Randomized, double-blind study of levamisole in recurrent aphthous stomatitis. (105101)	Drinnan A.J.... Fischman S.L.	1978
44	Levamisole in the treatment of recurrent aphthous stomatitis. (342850)	Van de Heyning J.	1978
45	Denture stomatitis. Effects of chlorhexidine and amphotericin B on the mycotic flora. (773085)	Olsen I.	1975
46	Treatment of aphthous stomatitis by suppression of intralesional streptococci. (4814943)	Shore R.N.... SHELLEY W.B.	1974
47	Contact stomatitis, glossitis, and cheilitis. (4417554)	Fisher A.A.	1974
48	The management of recurrent aphthous stomatitis. (14447178)	Sircus W.	1959
49	Aphthous stomatitis; the failure of local hydrocortisone therapy to affect healing time. (14364302)	RIVIN A.U.... Barton R.T.	1955
50	Severe unilateral aphthous stomatitis during early stages of multiple sclerosis; case report. (14811377)	DeMANGUS R.X.... LANGTON J.L.	1951

Genes related to Stomatitis

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc.
See all sources

Genes related to Stomatitis:

(show top 50) (show all 161)

id	Symbol	Description	Score	Implication
1	TP63	tumor protein p63	20.08	GeneCards inferred : Publications, Disorders, Gene name (show sections)
2	TNF	tumor necrosis factor	19.94	GeneCards inferred : Publications, Disorders (show sections)
3	MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	19.81	GeneCards inferred : Publications, Disorders (show sections)
4	IRF7	interferon regulatory factor 7	19.69	GeneCards inferred : Publications, Disorders (show sections)
5	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	19.56	GeneCards inferred : Publications, Disorders (show sections)
6	MVK	mevalonate kinase	19.44	GeneCards inferred : Disorders (show sections)
7	TBK1	TANK-binding kinase 1	19.31	GeneCards inferred : Publications, Disorders (show sections)
8	CFI	complement factor I	19.19	GeneCards inferred : Publications, Disorders (show sections)
9	CXCR3	chemokine (C-X-C motif) receptor 3	19.06	GeneCards inferred : Publications, Disorders (show sections)
10	VDI	vesicular stomatitis virus defective interfering particle suppression	18.95	GeneCards inferred : Publications, Disorders, Functions, Gene name (show sections)
11	CST1	cystatin SN	18.82	GeneCards inferred : Disorders (show sections)
12	MX2	myxovirus (influenza virus) resistance 2 (mouse)	18.69	GeneCards inferred : Publications, Disorders (show sections)
13	CGB7	chorionic gonadotropin, beta polypeptide 7	18.57	GeneCards inferred : Disorders (show sections)
14	CD69	CD69 molecule	18.44	GeneCards inferred : Publications, Disorders (show sections)
15	ERVW-1	endogenous retrovirus group W, member 1	18.32	GeneCards inferred : Publications, Disorders (show sections)
16	RNPEP	arginyl aminopeptidase (aminopeptidase B)	18.19	GeneCards inferred : Disorders (show sections)
17	STATH	statherin	18.07	GeneCards inferred : Disorders (show sections)
18	ALLC	allantoicase	17.95	GeneCards inferred : Disorders (show sections)
19	PPP6R1	protein phosphatase 6, regulatory subunit 1	17.82	GeneCards inferred : Disorders (show sections)
20	IRF3	interferon regulatory factor 3	17.70	GeneCards inferred : Publications, Disorders (show sections)
21	SLAMF1	signaling lymphocytic activation molecule family member 1	17.57	GeneCards inferred : Publications, Disorders (show sections)
22	MEFV	Mediterranean fever	17.45	GeneCards inferred : Publications, Disorders (show sections)
23	EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	17.32	GeneCards inferred : Publications, Disorders (show sections)
24	CD46	CD46 molecule, complement regulatory protein	17.20	GeneCards inferred : Publications, Disorders (show sections)
25	CD40	CD40 molecule, TNF receptor superfamily member 5	17.08	GeneCards inferred : Publications, Disorders (show sections)
26	LTA	lymphotoxin alpha	16.95	GeneCards inferred : Publications, Disorders (show sections)
27	CSN1S1	casein alpha s1	16.83	GeneCards inferred : Publications, Disorders (show sections)
28	CXCR1	chemokine (C-X-C motif) receptor 1	16.70	GeneCards inferred : Disorders (show sections)
29	NCS1	neuronal calcium sensor 1	16.58	GeneCards inferred : Disorders (show sections)
30	FAP	fibroblast activation protein, alpha	16.46	GeneCards inferred : Disorders (show sections)
31	REV1	REV1, polymerase (DNA directed)	16.33	GeneCards inferred : Disorders (show sections)
32	RHOU	ras homolog family member U	16.21	GeneCards inferred : Disorders (show sections)
33	CD4	CD4 molecule	16.08	GeneCards inferred : Publications, Disorders (show sections)
34	CGB5	chorionic gonadotropin, beta polypeptide 5	15.96	GeneCards inferred : Disorders (show sections)
35	IFNB1	interferon, beta 1, fibroblast	15.83	GeneCards inferred : Publications, Disorders (show sections)
36	CAT	catalase	15.71	GeneCards inferred : Publications, Disorders (show sections)
37	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	15.59	GeneCards inferred : Publications, Disorders (show sections)
38	IFNA1	interferon, alpha 1	15.46	GeneCards inferred : Publications, Disorders (show sections)
39	TKT	transketolase	15.34	GeneCards inferred : Publications, Disorders (show sections)
40	IL1A	interleukin 1, alpha	15.21	GeneCards inferred : Publications, Disorders (show sections)
41	IL1RN	interleukin 1 receptor antagonist	15.09	GeneCards inferred : Publications, Disorders (show sections)
42	TYMS	thymidylate synthetase	14.96	GeneCards inferred : Disorders (show sections)
43	NOS3	nitric oxide synthase 3 (endothelial cell)	14.84	GeneCards inferred : Publications, Disorders (show sections)
44	VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	14.72	GeneCards inferred : Publications, Disorders (show sections)
45	HLA-A	major histocompatibility complex, class I, A	14.59	GeneCards inferred : Publications, Disorders (show sections)
46	SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4	14.47	GeneCards inferred : Publications, Disorders (show sections)
47	IL1B	interleukin 1, beta	14.34	GeneCards inferred : Publications, Disorders (show sections)
48	IL10	interleukin 10	14.22	GeneCards inferred : Publications, Disorders (show sections)
49	IFNG	interferon, gamma	14.10	GeneCards inferred : Publications, Disorders (show sections)
50	SOD1	superoxide dismutase 1, soluble	13.97	GeneCards inferred : Publications, Disorders (show sections)

Products for genes related to Stomatitis disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	48	48	48
2	LSBio	-	-	50

Genetic Variations for Stomatitis

Expression for genes affiliated with Stomatitis

Sources:
¹BioGPS, ¹⁵Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Stomatitis

Search GEO for disease gene expression data for Stomatitis.

Pathways for genes affiliated with Stomatitis

Sources:
²⁹KEGG, ³⁷NCBI BioSystems Database, ⁵¹QIAGEN, ⁵²R&D Systems, ⁴Cell Signaling Technology, ⁵³Reactome
See all sources

Pathways related to Stomatitis according to GeneCards/GeneDecks:

(show all 18)

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	Influenza A²⁹ Hide members Measles²⁹ Herpes simplex infection²⁹	10.7	TNF, IRF3, IRF7, TBK1, IL12A, MX1
2	Toll-like receptor signaling pathway³⁷ Hide members Chagas disease (American trypanosomiasis)²⁹ Toll-like receptor signaling pathway²⁹ Hepatitis B²⁹	10.7	TNF, IRF3, IRF7, TBK1, IL12A
3	TRAF Pathway⁵¹ Hide members Toll-Like Receptors Pathway⁵¹ TNF Superfamily Pathway⁵¹	10.7	IL12A, TBK1, IRF7, IRF3, TNF
4	Hepatitis C²⁹	10.6	TBK1, IRF7, IRF3, TNF
5	Toll-Like receptor Signaling Pathways⁵² Hide members NOD-like Receptor Signaling Pathways⁵²	10.6	TBK1, IRF7, IRF3, TNF
6	NF-kappaB Signaling⁴	10.6	TBK1, IRF7, IRF3, TNF
7	Interferon Signaling⁵³ Hide members ISG15 antiviral mechanism⁵³ Cytokine Signaling in Immune system⁵³ Antiviral mechanism by IFN-stimulated genes⁵³ Cytokine Signaling in Immune system⁵³ Interferon gamma signaling⁵³	10.6	MX2, MX1, IRF7, IRF3
8	Immune response IFN alpha/beta signaling pathway Hide members Interferon alpha/beta signaling⁵³	10.6	MX2, MX1, IRF7, IRF3
9	Apoptosis Modulation and Signaling³⁷ Hide members Apoptosis³⁷	10.6	IRF7, IRF3, TNF
10	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways⁵³ Hide members RIG-I-like receptor signaling pathway²⁹ Negative regulators of RIG-I/MDA5 signaling⁵³	10.6	TNF, IRF3, IRF7
11	Pertussis²⁹	10.6	TNF, IRF3, IL12A
12	RIP-mediated NFkB activation via ZBP1⁵³ Hide members ZBP1(DAI) mediated induction of type I IFNs⁵³ Cellular Transformation by HTLV1⁵¹	10.6	TBK1, IRF3, TNF
13	TRAF6 mediated induction of TAK1 complex⁵³ Hide members Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon⁵³	10.6	IRF3, IRF7, TBK1
14	TRAF6 Mediated Induction of proinflammatory cytokines⁵³ Hide members Toll Like Receptor 4 (TLR4) Cascade⁵³ Activated TLR4 signalling⁵³ TRIF-mediated TLR3/TLR4 signaling ⁵³ Toll Like Receptor 3 (TLR3) Cascade⁵³ MyD88-independent cascade ⁵³ Toll-Like Receptors Cascades⁵³ Toll Like Receptor 9 (TLR9) Cascade⁵³ MyD88 dependent cascade initiated on endosome⁵³ Toll Like Receptor 7/8 (TLR7/8) Cascade⁵³	10.6	TBK1, IRF7, IRF3
15	Cytosolic DNA-sensing pathway²⁹ Hide members Cytosolic sensors of pathogen-associated DNA ⁵³	10.6	TBK1, IRF7, IRF3
16	TRAF6 mediated IRF7 activation⁵³ Hide members TRAF3-dependent IRF activation pathway⁵³	10.6	IRF3, IRF7, TBK1
17	IRF3-mediated induction of type I IFN⁵³ Hide members STAT6-mediated induction of chemokines⁵³ STING mediated induction of host immune responses⁵³ IRF3 mediated activation of type 1 IFN⁵³	10.5	TBK1, IRF3
18	Regulation of innate immune responses to cytosolic DNA⁵³	10.5	IRF3, TBK1

Compounds for genes affiliated with Stomatitis

Sources:
⁴⁴Novoseek, ¹¹DrugBank, ²⁸IUPHAR
See all sources

Compounds related to Stomatitis according to GeneCards/GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	serine⁴⁴	11.0	MVK, TNF, IRF7, TBK1, CD69, CXCR3
2	rantes⁴⁴	10.9	TNF, IRF3, IRF7, TBK1, CXCR3, MX1
3	poly(i-c)⁴⁴	10.9	MX1, CD69, TBK1, IRF7, IRF3, TNF
4	ifn-alpha⁴⁴	10.8	IRF3, IRF7, CXCR3, MX1
5	lipid⁴⁴	10.7	MVK, TNF, IRF3, CD69, MX1, CFI
6	polyinosinic-polycytidylic acid⁴⁴	10.7	TNF, IRF3, IRF7
7	2,5-oligoadenylate⁴⁴	10.7	TNF, IRF7, MX1
8	ly294002⁴⁴	10.6	CXCR3, CD69, IRF3, TNF
9	anakinra⁴⁴ ¹¹	11.5	TNF, MVK
10	isopentenyl diphosphate⁴⁴ ²⁸	11.3	MVK, CD69

GO Terms for genes affiliated with Stomatitis

Sources:
¹⁶Gene Ontology
See all sources

Biological processes related to Stomatitis according to GeneCards/GeneDecks:

(show all 17)

id	Name	GO ID	Score	Top Affiliating Genes
1	response to virus	GO:009615	11.0	MX1, IL12A, TBK1, IRF7, TNF
2	type I interferon-mediated signaling pathway	GO:060337	10.9	MX2, MX1, IRF7, IRF3
3	positive regulation of interferon-alpha production	GO:032727	10.9	IRF3, IRF7, TBK1
4	positive regulation of interferon-beta production	GO:032728	10.9	IRF3, IRF7, TBK1
5	defense response to Gram-positive bacterium	GO:050830	10.9	IL12A, TBK1, TNF
6	cytokine-mediated signaling pathway	GO:019221	10.8	IRF3, IRF7, MX1, MX2
7	MDA-5 signaling pathway	GO:039530	10.8	IRF7, IRF3
8	positive regulation of type I interferon production	GO:032481	10.8	TBK1, IRF7, IRF3
9	type I interferon biosynthetic process	GO:045351	10.8	IRF3, IRF7
10	TRIF-dependent toll-like receptor signaling pathway	GO:035666	10.7	TBK1, IRF7, IRF3
11	positive regulation of type I interferon-mediated signaling pathway	GO:060340	10.7	IRF7, IRF3
12	MyD88-independent toll-like receptor signaling pathway	GO:002756	10.7	IRF3, IRF7, TBK1
13	toll-like receptor 3 signaling pathway	GO:034138	10.7	TBK1, IRF7, IRF3
14	toll-like receptor 4 signaling pathway	GO:034142	10.6	IRF3, IRF7, TBK1
15	toll-like receptor signaling pathway	GO:002224	10.6	TBK1, IRF7, IRF3
16	innate immune response	GO:045087	10.6	CFI, MX1, TBK1, IRF7, IRF3
17	apoptotic process	GO:006915	10.4	TNF, IRF3, CXCR3, MX1, TP63