Summaries for Stomatitis

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Wikipedia:65 Stomatitis is inflammation of the mouth and lips. It refers to any inflammatory process affecting the... more...

MalaCards based summary: Stomatitis is related to behcet's disease and melanoma. An important gene associated with Stomatitis is TP63 (tumor protein p63), and among its related pathways are IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types and Malaria. The drugs sucralfate and carbamide peroxide and the compounds imiquimod and mycophenolate mofetil have been mentioned in the context of this disorder. Affiliated tissues include t cells, testes and colon, and related mouse phenotypes are homeostasis/metabolism and immune system.

Aliases & Classifications for Stomatitis

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Sources:
10Disease Ontology, 12DISEASES, 45Novoseek, 62UMLS, 35MeSH, 57SNOMED-CT, 40NCIt
See all sources

Stomatitis, Aliases & Descriptions:

Name: Stomatitis 10 12 45 62


External Ids:

Disease Ontology10 DOID:9637
MeSH35 D013280
NCIt40 C26887

Related Diseases for Stomatitis

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Graphical network of the top 20 diseases related to Stomatitis:



Diseases related to stomatitis

Symptoms for Stomatitis

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Drugs & Therapeutics for Stomatitis

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Drug clinical trials:

Search ClinicalTrials for Stomatitis

Search NIH Clinical Center for Stomatitis

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Stomatitis

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Anatomical Context for Stomatitis

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MalaCards organs/tissues related to Stomatitis:

33
T cells, Testes, Colon, Neutrophil, Brain, Tongue, Skin, Prostate, Bone, Tonsil, Endothelial, Heart, Breast, Monocytes, Bone marrow, Lung, B cells

Animal Models for Stomatitis or affiliated genes

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MGI Mouse Phenotypes related to Stomatitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.2TNF, TP63, IRF7, MEFV, CCR1, IL12A
2MP:00053877.6TNF, ISG15, TP63, IRF7, MEFV, CCR1

Publications for Stomatitis

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Articles related to Stomatitis:

(show top 50)    (show all 1230)
idTitleAuthorsYear
1
Transmitted/Founder simian immunodeficiency virus envelope sequences in vesicular stomatitis and semliki forest virus vector immunized rhesus macaques. (25360552)
2014
2
Antifungal medications or disinfectants for denture stomatitis. (24971864)
2014
3
Experimental simulation of radio- and chemoradio stomatitis in rats. (23658931)
2013
4
Assessment of immediate pain relief with laser treatment in recurrent aphthous stomatitis. (23622766)
2013
5
Efficacy of omega-3 in treatment of recurrent aphthous stomatitis and improvement of quality of life: a randomized, double-blind, placebo-controlled study. (24268387)
2013
6
Bovine papular stomatitis affecting dairy cows and milkers in midwestern Brazil. (22362531)
2012
7
Complexes of vesicular stomatitis virus matrix protein with host Rae1 and Nup98 involved in inhibition of host transcription. (23028327)
2012
8
A case of resistant adult-onset periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome responsive to anakinra. (22931584)
2012
9
Systemic interventions for recurrent aphthous stomatitis (mouth ulcers). (22972085)
2012
10
Elucidating role of salivary proteins in denture stomatitis using a proteomic approach. (23041753)
2012
11
A recombinant vesicular stomatitis virus bearing a lethal mutation in the glycoprotein gene uncovers a second site suppressor that restores fusion. (21680501)
2011
12
Domestic cattle as a non-conventional amplifying host of vesicular stomatitis New Jersey virus. (21133963)
2011
13
Lesion development and replication kinetics during early infection in cattle inoculated with Vesicular stomatitis New Jersey virus via scarification and black fly (Simulium vittatum) bite. (20858740)
2011
14
Distinct patterns of stomatitis with concurrent cetuximab and radiotherapy for head and neck squamous cell carcinoma. (21852185)
2011
15
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). (20824883)
2010
16
Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis. (20173724)
2010
17
Down-regulation of type I interferon receptor sensitizes bladder cancer cells to vesicular stomatitis virus-induced cell death. (19957332)
2010
18
Ageing exacerbates damage of systemic and salivary neutrophils from patients presenting Candida-related denture stomatitis. (19327169)
2009
19
In vivo biodistribution of a highly attenuated recombinant vesicular stomatitis virus expressing HIV-1 Gag following intramuscular, intranasal, or intravenous inoculation. (19428903)
2009
20
Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization. (19390604)
2009
21
Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitro. (16507098)
2006
22
Effect of low-level laser therapy on Candida albicans growth in patients with denture stomatitis. (15954824)
2005
23
Characterization of the chicken PKR: polymorphism of the gene and antiviral activity against vesicular stomatitis virus. (15070037)
2004
24
Results of double-blind placebo-controlled challenge with nickel salts in patients affected by recurrent aphthous stomatitis. (12915773)
2003
25
IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS). (12140751)
2002
26
Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98. (11106761)
2000
27
Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. (10393612)
1999
28
Chronic ulcerative stomatitis. (9292078)
1997
29
Existence of Candida albicans and microorganisms in denture stomatitis patients. (9372471)
1997
30
Decreased levels of salivary prostaglandin E2 and epidermal growth factor in recurrent aphthous stomatitis. (8850647)
1995
31
Denture stomatitis and ABO blood types. (1800738)
1991
32
Aphthous stomatitis and its management. (1807480)
1991
33
Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein. (2161946)
1990
34
Characterization of a macrophage-tropic HIV strain that does not alter macrophage cytokine production yet protects macrophages from superinfection by vesicular stomatitis virus. (2171598)
1990
35
Immunological and histological studies on denture stomatitis in children: a pilot study. (2478985)
1988
36
Candidal antibodies in patients undergoing treatment for denture stomatitis. (3298628)
1987
37
Prevalence and persistence of different strains of Candida albicans in treatment of denture stomatitis. (2985776)
1985
38
Recurrent aphthous stomatitis. (4025106)
1985
39
Recurrent aphthous stomatitis: review of the literature. (6214531)
1982
40
Replication of dengue, yellow fever, St. Louis encephalitis and vesicular stomatitis viruses in a cell line (TRA-171) derived from Toxorhynchites amboinensis. (6119288)
1981
41
Effect of nystatin in the treatment of denture stomatitis. (6936771)
1980
42
Yeast colonization in the oral cavity and feces in patients with denture stomatitis. (371327)
1979
43
Double-blind study of levamisole in aphthous stomatitis. (105099)
1978
44
Evaluation of the therapeutic effect of levamisole in treatment of recurrent aphthous stomatitis. (105100)
1978
45
Aphthous stomatitis as a featuring syndrome of emotional stress in dental treatment. (1076577)
1976
46
Incidence of immediate and delayed hypersensitivity to Candida albicans in denture stomatitis. (4933599)
1971
47
Recurrent aphthous stomatitis. Clinical, therapeutic, histopathologic, and hypersensitivity aspects. (5952294)
1966
48
Antihistaminic agents in the treatment of recurrent aphthous stomatitis. (13037294)
1953
49
Glossitis and stomatitis due to penicillin lozenges and troches. (21016496)
1946
50
Ulcerative Stomatitis in Children. (19975517)
1911

Variations for Stomatitis

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Expression for genes affiliated with Stomatitis

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Search GEO for disease gene expression data for Stomatitis.

Pathways for genes affiliated with Stomatitis

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Pathways related to Stomatitis according to GeneCards/GeneDecks:

(show all 17)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8IL12A, TNF
29.8TNF, IL12A
39.8TNF, IL12A
49.8TNF, IL12A
59.8TNF, IL12A
69.8TNF, IL12A
7
Show member pathways
IL27-mediated signaling events38
9.8TNF, IL12A
8
Show member pathways
Apoptosis Modulation and Signaling38
Apoptosis38
9.5TNF, TP63, IRF7
9
Show member pathways
9.4IL12A, TNF, IRF7
10
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
9.4TNF, IL12A, IRF7
11
Show member pathways
9.3ISG15, IRF7, MX1
12
Show member pathways
9.3MX1, ISG15, IRF7
13
Show member pathways
9.1IL12A, TNF, CCR1, FGF20
14
Show member pathways
9.1TNF, CCR1, IL12A, FGF20
15
Show member pathways
9.1TNF, CCR1, IL12A, FGF20
16
Show member pathways
9.1IL12A, ISG15, TNF, IRF7
17
Show member pathways
9.0IL12A, TNF, MX1, IRF7

Compounds for genes affiliated with Stomatitis

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Compounds related to Stomatitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1imiquimod45 61 30 1313.0MX1, TNF
2mycophenolate mofetil45 51 1311.9IL12A, TNF
3polyinosinic-polycytidylic acid459.9TNF, IRF7
4neopterin459.8MX1, TNF
5ccl345 3010.7CCR1, TNF
6poly(i-c)459.6TNF, IRF7, MX1
7ifn-alpha459.3MX1, IRF7
82,5-oligoadenylate459.3MX1, IRF7, ISG15, TNF
9cycloheximide459.3TNF, ISG15, CCR1, MX1
10retinoic acid45 2610.2TNF, ISG15, TP63, CCR1
11rantes459.2MX1, CCR1, IRF7, TNF
12leucine458.6ISG15, ELOF1, MEFV, CCR1, MX1

GO Terms for genes affiliated with Stomatitis

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Biological processes related to Stomatitis according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1response to type I interferonGO:003434010.0MX1, ISG15
2defense response to Gram-positive bacteriumGO:00508309.9IL12A, TNF
3positive regulation of osteoclast differentiationGO:00456729.9CCR1, TNF
4extrinsic apoptotic signaling pathwayGO:00971919.8TNF, IL12A
5negative regulation of gene expressionGO:00106299.8CCR1, TNF
6negative regulation of viral genome replicationGO:00450719.8MX1, ISG15, TNF
7positive regulation of interferon-gamma productionGO:00327299.7IL12A, TNF
8positive regulation of ERK1 and ERK2 cascadeGO:00703749.6FGF20, CCR1, TNF
9type I interferon signaling pathwayGO:00603379.5ISG15, IRF7, MX1
10response to virusGO:00096159.3MX1, IL12A, IRF7, TNF
11cytokine-mediated signaling pathwayGO:00192219.2ISG15, IRF7, CCR1, MX1
12inflammatory responseGO:00069549.0CCR1, MEFV, TNF
13innate immune responseGO:00450878.7ISG15, IRF7, MEFV, MX1, FGF20

Products for genes affiliated with Stomatitis

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Sources for Stomatitis

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet