MCID: STM007
MIFTS: 51

Stomatitis malady

Oral diseases category
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Summaries for Stomatitis

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Wikipedia:65 Stomatitis is inflammation of the mouth and lips. It refers to any inflammatory process affecting the... more...

MalaCards based summary: Stomatitis is related to behcet's disease and familial mediterranean fever. An important gene associated with Stomatitis is TP63 (tumor protein p63), and among its related pathways are MSP-RON Signaling and African trypanosomiasis. The drugs sucralfate and carbamide peroxide and the compounds imiquimod and mycophenolate mofetil have been mentioned in the context of this disorder. Affiliated tissues include t cells, testes and colon, and related mouse phenotypes are homeostasis/metabolism and immune system.

Aliases & Classifications for Stomatitis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt
See all sources

Stomatitis, Aliases & Descriptions:

Name: Stomatitis 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


External Ids:

Disease Ontology8 DOID:9637
MeSH34 D013280
NCIt39 C26887

Related Diseases for Stomatitis

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Graphical network of the top 20 diseases related to Stomatitis:



Diseases related to stomatitis

Symptoms for Stomatitis

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Drugs & Therapeutics for Stomatitis

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Drug clinical trials:

Search ClinicalTrials for Stomatitis

Search NIH Clinical Center for Stomatitis

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Stomatitis

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Anatomical Context for Stomatitis

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MalaCards organs/tissues related to Stomatitis:

32
T cells, Testes, Colon, Neutrophil, Brain, Tongue, Skin, Bone, Prostate, Endothelial, Heart, Breast, Monocytes, Bone marrow, Lung, Tonsil, B cells

Animal Models for Stomatitis or affiliated genes

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MGI Mouse Phenotypes related to Stomatitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.2IL12A, CCR1, MEFV, IRF7, TP63, TNF
2MP:00053877.6IL12A, TNF, ISG15, TP63, IRF7, MEFV

Publications for Stomatitis

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Articles related to Stomatitis:

(show top 50)    (show all 1192)
idTitleAuthorsYear
1
Transmitted/Founder simian immunodeficiency virus envelope sequences in vesicular stomatitis and semliki forest virus vector immunized rhesus macaques. (25360552)
2014
2
Antifungal medications or disinfectants for denture stomatitis. (24971864)
2014
3
Experimental simulation of radio- and chemoradio stomatitis in rats. (23658931)
2013
4
Assessment of immediate pain relief with laser treatment in recurrent aphthous stomatitis. (23622766)
2013
5
Efficacy of omega-3 in treatment of recurrent aphthous stomatitis and improvement of quality of life: a randomized, double-blind, placebo-controlled study. (24268387)
2013
6
Bovine papular stomatitis affecting dairy cows and milkers in midwestern Brazil. (22362531)
2012
7
Complexes of vesicular stomatitis virus matrix protein with host Rae1 and Nup98 involved in inhibition of host transcription. (23028327)
2012
8
A case of resistant adult-onset periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome responsive to anakinra. (22931584)
2012
9
Systemic interventions for recurrent aphthous stomatitis (mouth ulcers). (22972085)
2012
10
Elucidating role of salivary proteins in denture stomatitis using a proteomic approach. (23041753)
2012
11
A recombinant vesicular stomatitis virus bearing a lethal mutation in the glycoprotein gene uncovers a second site suppressor that restores fusion. (21680501)
2011
12
Domestic cattle as a non-conventional amplifying host of vesicular stomatitis New Jersey virus. (21133963)
2011
13
Lesion development and replication kinetics during early infection in cattle inoculated with Vesicular stomatitis New Jersey virus via scarification and black fly (Simulium vittatum) bite. (20858740)
2011
14
Distinct patterns of stomatitis with concurrent cetuximab and radiotherapy for head and neck squamous cell carcinoma. (21852185)
2011
15
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). (20824883)
2010
16
Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis. (20173724)
2010
17
Down-regulation of type I interferon receptor sensitizes bladder cancer cells to vesicular stomatitis virus-induced cell death. (19957332)
2010
18
Ageing exacerbates damage of systemic and salivary neutrophils from patients presenting Candida-related denture stomatitis. (19327169)
2009
19
Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization. (19390604)
2009
20
Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitro. (16507098)
2006
21
Effect of low-level laser therapy on Candida albicans growth in patients with denture stomatitis. (15954824)
2005
22
Characterization of the chicken PKR: polymorphism of the gene and antiviral activity against vesicular stomatitis virus. (15070037)
2004
23
Results of double-blind placebo-controlled challenge with nickel salts in patients affected by recurrent aphthous stomatitis. (12915773)
2003
24
IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS). (12140751)
2002
25
Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98. (11106761)
2000
26
Oral and maxillofacial pathology case of the month. Recurrent aphthous stomatitis--herpetiform type. (11857822)
2000
27
Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. (10393612)
1999
28
Chronic ulcerative stomatitis. (9292078)
1997
29
Existence of Candida albicans and microorganisms in denture stomatitis patients. (9372471)
1997
30
Decreased levels of salivary prostaglandin E2 and epidermal growth factor in recurrent aphthous stomatitis. (8850647)
1995
31
Denture stomatitis and ABO blood types. (1800738)
1991
32
Aphthous stomatitis and its management. (1807480)
1991
33
Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein. (2161946)
1990
34
Characterization of a macrophage-tropic HIV strain that does not alter macrophage cytokine production yet protects macrophages from superinfection by vesicular stomatitis virus. (2171598)
1990
35
Immunological and histological studies on denture stomatitis in children: a pilot study. (2478985)
1988
36
Candidal antibodies in patients undergoing treatment for denture stomatitis. (3298628)
1987
37
Prevalence and persistence of different strains of Candida albicans in treatment of denture stomatitis. (2985776)
1985
38
Recurrent aphthous stomatitis. (4025106)
1985
39
Recurrent aphthous stomatitis: review of the literature. (6214531)
1982
40
Replication of dengue, yellow fever, St. Louis encephalitis and vesicular stomatitis viruses in a cell line (TRA-171) derived from Toxorhynchites amboinensis. (6119288)
1981
41
Effect of nystatin in the treatment of denture stomatitis. (6936771)
1980
42
Yeast colonization in the oral cavity and feces in patients with denture stomatitis. (371327)
1979
43
Double-blind study of levamisole in aphthous stomatitis. (105099)
1978
44
Evaluation of the therapeutic effect of levamisole in treatment of recurrent aphthous stomatitis. (105100)
1978
45
Aphthous stomatitis as a featuring syndrome of emotional stress in dental treatment. (1076577)
1976
46
Incidence of immediate and delayed hypersensitivity to Candida albicans in denture stomatitis. (4933599)
1971
47
Recurrent aphthous stomatitis. Clinical, therapeutic, histopathologic, and hypersensitivity aspects. (5952294)
1966
48
Antihistaminic agents in the treatment of recurrent aphthous stomatitis. (13037294)
1953
49
Glossitis and stomatitis due to penicillin lozenges and troches. (21016496)
1946
50
Ulcerative Stomatitis in Children. (19975517)
1911

Variations for Stomatitis

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Expression for genes affiliated with Stomatitis

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Expression patterns in normal tissues for genes affiliated with Stomatitis

Search GEO for disease gene expression data for Stomatitis.

Pathways for genes affiliated with Stomatitis

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Pathways related to Stomatitis according to GeneCards/GeneDecks:

(show all 17)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8IL12A, TNF
29.8IL12A, TNF
39.8IL12A, TNF
49.8IL12A, TNF
5
Show member pathways
9.8IL12A, TNF
6
Show member pathways
IL27-mediated signaling events37
9.8TNF, IL12A
79.8TNF, IL12A
8
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
9.5IRF7, TP63, TNF
9
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
9.4TNF, IRF7, IL12A
10
Show member pathways
9.4TNF, IRF7, IL12A
11
Show member pathways
9.3ISG15, IRF7, MX1
12
Show member pathways
9.3MX1, IRF7, ISG15
13
Show member pathways
9.1FGF20, IL12A, CCR1, TNF
14
Show member pathways
9.1TNF, CCR1, IL12A, FGF20
15
Show member pathways
9.1TNF, CCR1, IL12A, FGF20
16
Show member pathways
9.1IL12A, IRF7, ISG15, TNF
17
Show member pathways
9.0TNF, IRF7, IL12A, MX1

Compounds for genes affiliated with Stomatitis

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Compounds related to Stomatitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1imiquimod44 61 28 1113.0MX1, TNF
2mycophenolate mofetil44 50 1111.9IL12A, TNF
3polyinosinic-polycytidylic acid449.9TNF, IRF7
4neopterin449.8MX1, TNF
5ccl344 2810.7CCR1, TNF
6poly(i-c)449.6TNF, IRF7, MX1
7ifn-alpha449.3MX1, IRF7
82,5-oligoadenylate449.3MX1, IRF7, ISG15, TNF
9cycloheximide449.3TNF, ISG15, CCR1, MX1
10retinoic acid44 2410.2TNF, ISG15, TP63, CCR1
11rantes449.2MX1, CCR1, IRF7, TNF
12leucine448.6ISG15, ELOF1, MEFV, CCR1, MX1

GO Terms for genes affiliated with Stomatitis

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Biological processes related to Stomatitis according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1response to type I interferonGO:03434010.0MX1, ISG15
2defense response to Gram-positive bacteriumGO:0508309.9IL12A, TNF
3positive regulation of osteoclast differentiationGO:0456729.9CCR1, TNF
4extrinsic apoptotic signaling pathwayGO:0971919.8TNF, IL12A
5negative regulation of gene expressionGO:0106299.8CCR1, TNF
6negative regulation of viral genome replicationGO:0450719.8MX1, ISG15, TNF
7positive regulation of interferon-gamma productionGO:0327299.7IL12A, TNF
8positive regulation of ERK1 and ERK2 cascadeGO:0703749.6FGF20, CCR1, TNF
9type I interferon signaling pathwayGO:0603379.5ISG15, IRF7, MX1
10response to virusGO:0096159.3MX1, IL12A, IRF7, TNF
11cytokine-mediated signaling pathwayGO:0192219.2ISG15, IRF7, CCR1, MX1
12inflammatory responseGO:0069549.0CCR1, MEFV, TNF
13innate immune responseGO:0450878.7ISG15, IRF7, MEFV, MX1, FGF20

Products for genes affiliated with Stomatitis

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Sources for Stomatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet