MCID: STR020
MIFTS: 44

Strabismus malady

Genetic diseases, Eye diseases, Rare diseases categories

Aliases & Classifications for Strabismus

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Sources:
9Disease Ontology, 20GeneTests, 43Novoseek, 22GTR, 60UMLS, 55SNOMED-CT, 27ICD9CM, 25ICD10
See all sources

Strabismus, Aliases & Descriptions:

Name: Strabismus 9 20 43 22 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology9 DOID:540
ICD9CM27 378.7
ICD1025 H50.8, H50.9

Summaries for Strabismus

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Wikipedia:63 Strabismus (/str??b?zm?s/, from Greek strabism more...

MalaCards based summary: Strabismus is related to hyperopia and amblyopia. An important gene associated with Strabismus is VANGL2 (VANGL planar cell polarity protein 2), and among its related pathways is Wnt Signaling Pathway. The drugs botulinum toxin type a and isoflurophate have been mentioned in the context of this disorder. Affiliated tissues include eye, thyroid and testes, and related mouse phenotypes are limbs/digits/tail and respiratory system.

Related Diseases for Strabismus

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Graphical network of the top 20 diseases related to Strabismus:



Diseases related to strabismus

Symptoms for Strabismus

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Drugs & Therapeutics for Strabismus

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Drug clinical trials:

Search ClinicalTrials for Strabismus

Search NIH Clinical Center for Strabismus

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Strabismus

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Genetic tests related to Strabismus:

id Genetic test Affiliating Genes
1 Strabismus20
2 Susceptibility to Strabismus22

Anatomical Context for Strabismus

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MalaCards organs/tissues related to Strabismus:

31
Eye, Thyroid, Testes, Cortex, Brain, Bone, Skin

Animal Models for Strabismus or affiliated genes

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Publications for Strabismus

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Articles related to Strabismus:

(show top 50)    (show all 660)
idTitleAuthorsYear
1
Strabismus Surgical Subspecialization: A Population-Based Analysis. (25719856)
2015
2
Effects of Strabismic Amblyopia and Strabismus only on Visuomotor Behaviour: Part III. Temporal Eye-Hand Coordination during Reaching. (25389201)
2014
3
Horizontal and vertical optokinetic eye movements in macaque monkeys with infantile strabismus: directional bias and crosstalk. (24204052)
2014
4
Strabismus resulting from an anomalous extraocular muscle in Gorlin syndrome. (25266843)
2014
5
Origins of strabismus and loss of binocular vision. (25309358)
2014
6
Fibrin glue for closure of conjunctival incision in strabismus surgery: a report by the american academy of ophthalmology. (23820078)
2013
7
Strabismus disrupts binocular synaptic integration in primary visual cortex. (24155315)
2013
8
Infectious Pseudomonas scleritis after strabismus surgery. (23871294)
2013
9
The effect of previous orbital decompression on results of strabismus surgery in patients with Graves' ophthalmopathy. (23528374)
2013
10
The long-term psychosocial impact of corrective surgery for adults with strabismus. (23410730)
2013
11
Strabismus among aged Medicare beneficiaries: impact of health status and region. (23928005)
2013
12
Analysis of visual outcomes and complications following levator resection for unilateral congenital blepharoptosis without strabismus. (23989313)
2013
13
Short-term response of mitomycin C on the human rectus muscle following strabismus surgery: histological, ultrastructural, and biomechanical evaluation. (23380007)
2013
14
Accurate gaze direction measurements with free head movement for strabismus angle estimation. (23399951)
2013
15
Acquired paralytic strabismus in Southern Taiwan. (23608076)
2013
16
Loop suture technique for optional adjustment in strabismus surgery. (24014986)
2013
17
Successful extraocular muscle re-resection for a strabismus surgery complication: a "snapped" [severed, inadvertently] and retrieved inferior rectus muscle: a case report. (22404092)
2012
18
Intraorbital epidermoid cyst: a 5-year-old with exophthalmos and strabismus. (22446470)
2012
19
Prisms are effective in resolving diplopia from incomitant, large, and combined strabismus. (22467592)
2012
20
Ocular alignment and results of strabismus surgery in neurologically impaired children. (22553767)
2012
21
Horizontal strabismus worldwide--what are the risk factors? (22568423)
2012
22
Design and efficacy of surgery for horizontal idiopathic nystagmus with abnormal head posture and strabismus. (22038360)
2011
23
Augmented vertical rectus [corrected] transposition for the treatment of strabismus in MAPbius syndrome. (22153406)
2011
24
Social phobia and other psychiatric problems in children with strabismus. (21784213)
2011
25
Periosteal Flap fixation of the Globe for Surgical Treatment of Severe Restrictive Strabismus: A Report of Eight Cases with Outcomes. (22204549)
2011
26
Insertion slanting strabismus surgical procedures. (22159685)
2011
27
Horizontal strabismus surgery in children and adults. (22035312)
2011
28
Prevalence of and early-life influences on childhood strabismus: findings from the Millennium Cohort Study. (20194258)
2010
29
Pure horizontal strabismus in inferior oblique inclusion syndrome. (21117524)
2010
30
Paralytic strabismus: third, fourth, and sixth nerve palsy. (20638001)
2010
31
The use of titanium T-plate as platform for globe alignment in severe paralytic and restrictive strabismus. (20542486)
2010
32
Epidemiology of surgical strabismus in Saudi Arabia. (20868257)
2010
33
Strabismus following bilateral cataract surgery in childhood. (20700792)
2010
34
Comparison of alternate cover test reliability at near in non-strabismus between experienced and novice examiners. (20444138)
2010
35
In-utero exposure to smoking, alcohol, coffee, and tea and risk of strabismus. (20338975)
2010
36
Predictability of strabismus surgery in children with developmental disorders and/or psychomotor retardation. (20804359)
2009
37
Ocular alignment following strabismus surgery. (19321471)
2009
38
Duration of conjunctival redness following adult strabismus surgery. (20006822)
2009
39
Inferior oblique surgery for restrictive strabismus in patients with thyroid orbitopathy. (20126484)
2009
40
Prevalence and pattern of strabismus in Ilorin. (20425742)
2009
41
Effects of amniotic membrane on wound healing and adhesions in experimental strabismus surgery. (19882591)
2009
42
Beware angle kappa: an unusual problem following strabismus surgery. (20001511)
2009
43
Genes on bovine chromosome 18 associated with bilateral convergent strabismus with exophthalmos in German Brown cattle. (18836565)
2008
44
Photorefractive keratectomy followed by strabismus surgery for the treatment of partly accommodative esotropia. (15616503)
2004
45
The aniseikonia answer is "The Aniseikonia Inspector" CD; strabismus surgery problems; ocular "PT"; monovision followup. (12765539)
2003
46
Major review: the clinical spectrum of pediatric myasthenia gravis: blepharoptosis, ophthalmoplegia and strabismus. A report of 14 cases. (12171588)
2002
47
The outcome of strabismus surgery in childhood exotropia. (8925940)
1996
48
A prospective study of the relationship between strabismus and head posture in patients with frontal plagiocephaly. (8618990)
1996
49
Botulinum isn't just a poison anymore. Botulinum toxin in treatment of strabismus and essential blepharospasm. (3974563)
1985
50
Anisometropia and strabismus. (900611)
1977

Variations for Strabismus

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Expression for genes affiliated with Strabismus

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Search GEO for disease gene expression data for Strabismus.

Pathways for genes affiliated with Strabismus

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Pathways related to Strabismus according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Wnt Signaling Pathway NetPath36
9.6VANGL1, VANGL2

Compounds for genes affiliated with Strabismus

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GO Terms for genes affiliated with Strabismus

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Cellular components related to Strabismus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1apical plasma membraneGO:00163249.2VANGL2, GPR143
2lysosomal membraneGO:00057658.7MCOLN1, GPR143
3plasma membraneGO:00058867.5FGFR3, VANGL1, VANGL2, MCOLN1, GPR143

Biological processes related to Strabismus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1digestive tract morphogenesisGO:00485469.4FGFR3, VANGL2
2somatic stem cell maintenanceGO:00350199.2FGFR3, VANGL2
3phosphatidylinositol-mediated signalingGO:00480159.1FGFR3, GPR143

Products for genes affiliated with Strabismus

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Sources for Strabismus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet