MCID: STR021
MIFTS: 37

Struma Ovarii malady

Category: Cancer diseases

Aliases & Classifications for Struma Ovarii

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Aliases & Descriptions for Struma Ovarii:

Name: Struma Ovarii 11 49 38 13 67
 
Struma Ovarii Nos 11

Classifications:



External Ids:

Disease Ontology11 DOID:2640
MeSH38 D013330
SNOMED-CT61 189851000, 24327009
NCIt44 C7468

Summaries for Struma Ovarii

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Wikipedia:70 A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains... more...

MalaCards based summary: Struma Ovarii, also known as struma ovarii nos, is related to hashimoto thyroiditis and malignant struma ovarii. An important gene associated with Struma Ovarii is TG (Thyroglobulin), and among its related pathways are Thyroxine (Thyroid Hormone) Production and Central carbon metabolism in cancer. Affiliated tissues include thyroid, ovary and liver, and related mouse phenotypes are digestive/alimentary and hematopoietic system.

Related Diseases for Struma Ovarii

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Diseases in the Struma Ovarii family:

Malignant Struma Ovarii Benign Struma Ovarii

Diseases related to Struma Ovarii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1hashimoto thyroiditis29.1BRAF, RET, TG, TSHR
2malignant struma ovarii12.3
3benign struma ovarii12.3
4thyroiditis10.8
5meige syndrome10.5
6pseudo-meigs syndrome10.5
7hyperthyroidism10.5
8graves' disease10.4
9thyroid cancer10.4
10teratoma10.4
11peritonitis10.3
12transient hypogammaglobulinemia of infancy10.3NKX2-1, TG
13crohn's disease of the esophagus10.3TG, TSHR
14acquired central diabetes insipidus10.3TG, TSHR
15adult teratoma10.2NKX2-1, TG
16papillary carcinoma10.2
17presbyopia10.2TG, TSHR
18hypertelorism, preauricular sinus, punctal pits, and deafness10.2TG, TSHR
19substernal goiter10.2TG, TSHR
20cystadenoma10.2
21adenoma10.2
22glaucomatocyclitic crisis10.2TG, TSHR
23cd3zeta deficiency10.2TG, TSHR
24central nervous system hemangioma10.1TG, TSHR
25hypothyroidism10.1
26cervicitis10.1
27hereditary conventional renal cell carcinoma10.1TG, TSHR
28dysgraphia10.1NKX2-1, TG
29blood group incompatibility10.1TG, TSHR
30dermoid cyst10.0
31cystic teratoma10.0
32adenocarcinoma10.0
33alveoli adenoma10.0TG, TSHR
34pterygium colli mental retardation digital anomalies10.0BRAF, KRAS
35rad51c-related fanconi anemia10.0BRAF, KRAS
36pulmonary venoocclusive disease10.0BRAF, KRAS
37mediastinum teratoma9.9BRAF, KRAS
38fibroma9.9BRAF, KRAS
39radioulnar synostosis9.9BRAF, KRAS
40intermittent proptosis9.9TG, TSHR
41pseudounicornuate uterus9.9KRAS, NKX2-1
42breast cancer9.9
43gonadoblastoma9.9
44goiter9.9
45ovarian cancer9.9
46mucinous ovarian cystadenoma9.9
47ovarian cystadenoma9.9
48cerebritis9.9
49sertoli cell tumor9.9
50pituitary adenoma9.9

Graphical network of the top 20 diseases related to Struma Ovarii:



Diseases related to struma ovarii

Symptoms for Struma Ovarii

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Drugs & Therapeutics for Struma Ovarii

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Drugs for Struma Ovarii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Hormones, Hormone Substitutes, and Hormone Antagonists12767
2Hormones13979
3Hormone Antagonists12778

Interventional clinical trials:

idNameStatusNCT IDPhase
1Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer TreatmentCompletedNCT01441154

Search NIH Clinical Center for Struma Ovarii


Cochrane evidence based reviews: struma ovarii

Genetic Tests for Struma Ovarii

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Anatomical Context for Struma Ovarii

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MalaCards organs/tissues related to Struma Ovarii:

35
Thyroid, Ovary, Liver, Bone, Testes, Pituitary, Thymus

Animal Models for Struma Ovarii or affiliated genes

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MGI Mouse Phenotypes related to Struma Ovarii:

40 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.0BRAF, KRAS, NKX2-1, RET
2MP:00053978.4BRAF, KRAS, RET, TG, TSHR
3MP:00053868.4BRAF, KRAS, NKX2-1, RET, TSHR
4MP:00020068.3BRAF, KRAS, NKX2-1, RET, TSHR
5MP:00053898.2BRAF, KRAS, NKX2-1, RET, TSHR
6MP:00053888.2BRAF, KRAS, NKX2-1, RET
7MP:00053798.0BRAF, KRAS, NKX2-1, RET, TG, TSHR
8MP:00053788.0BRAF, KRAS, NKX2-1, RET, TG, TSHR
9MP:00053767.9BRAF, KRAS, NKX2-1, RET, TG, TSHR
10MP:00036317.9BRAF, KRAS, NKX2-1, RET, TG, TSHR

Publications for Struma Ovarii

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Articles related to Struma Ovarii:

(show top 50)    (show all 312)
idTitleAuthorsYear
1
Novel BRAF and KRAS Mutations in Papillary Thyroid Carcinoma Arising in Struma Ovarii. (26362194)
2015
2
Diffusion-weighted magnetic resonance imaging findings in a patient with struma ovarii. (25272567)
2014
3
Papillary thyroid cancer in a struma ovarii: a report of a rare case. (25402391)
2014
4
131I Therapy Using rhTSH Stimulation and Dosimetry in Metastatic Malignant Struma Ovarii. (24152665)
2014
5
Re: coexistence of struma ovarii and serous cystadenoma of the ovary. (23202789)
2013
6
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review. (23412916)
2013
7
Two cases of malignant struma ovarii with metastasis to pelvic bone. (23391779)
2013
8
Delayed treatment of papillary thyroid carcinoma arising from struma ovarii in a patient with history of bilateral salpingo-oophorectomy: a case report. (22068256)
2012
9
Struma ovarii presenting with Hashimoto's thyroiditis: a case report. (22152685)
2011
10
Thyroid-type solid cell nests in struma ovarii. (20034983)
2011
11
Struma ovarii and peritoneal strumosis with thyrotoxicosis. (19265502)
2009
12
Histologically bland "extremely well differentiated" thyroid carcinomas arising in struma ovarii can recur and metastasize. (19620939)
2009
13
Struma ovarii: CT findings. (18214583)
2008
14
Struma Ovarii with a focus of follicular variant of papillary thyroid cancer: a case report. (18646677)
2008
15
A case of metastatic struma ovarii treated with 131I therapy: focus on preservation of fertility and selected review of the literature. (18584410)
2008
16
Struma ovarii associated with hyperthyroidism, elevated CA 125 and pseudo-Meigs syndrome may mimic advanced ovarian cancer. (18618418)
2008
17
Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature. (18334015)
2008
18
Cytologic differentiation of struma ovarii from other ovarian neoplasms. (18323278)
2008
19
Struma ovarii with pseudo-Meigs' syndrome and elevated CA125 levels. (17365481)
2007
20
Benign struma ovarii in a patient with invasive papillary thyroid cancer: detection with I-131 SPECT-CT. (17452868)
2007
21
BRAF T1799A mutation occurring in a case of malignant struma ovarii. (17478764)
2007
22
Malignant struma ovarii mimic clear cell carcinoma. (14986024)
2005
23
Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report. (15262148)
2004
24
Hypothyroidism due to Hashimoto thyroiditis post struma ovarii excision. (15235706)
2004
25
Pregnancy following treated malignant struma ovarii. (15524228)
2004
26
Struma ovarii: US and CT findings. (14527060)
2003
27
Struma ovarii coexisting with mucinous cystadenoma detected by radioactive iodine. (12972992)
2003
28
Benign struma ovarii complicating pregnancy: a case report and review of the literature. (12937924)
2003
29
Conservative therapy for malignant struma ovarii. A case report. (12497687)
2002
30
Struma ovarii: a rare benign pathology which may erroneously suggest malignancy. (11703211)
2001
31
Coexistence of Graves' disease and struma ovarii: case report and literature review. (11456276)
2001
32
Malignant struma ovarii: an unusual presentation. (11575860)
2001
33
Cystic struma ovarii: imaging findings. (10864077)
2000
34
Diagnosis and treatment of disseminated struma ovarii with malignant transformation. (9062167)
1997
35
Struma ovarii simulating ovarian tumors of other types. A report of 30 cases. (7802134)
1995
36
Limitations of CA125 in the preoperative evaluation of a pelvic mass: struma ovarii and ascites. (8216132)
1993
37
Metastatic malignant struma ovarii presenting as paraparesis from a spinal metastasis. (2738669)
1989
38
Struma ovarii: a case report. (3377718)
1988
39
Struma ovarii: a case report. (3455373)
1987
40
Malignant struma ovarii. Light and electron microscopic study. (6821820)
1983
41
Struma ovarii: report of a case with malignant evolution and of another observed in the course of pregnancy. (7341272)
1980
42
Ascites and hydrothorax in association with struma ovarii. (943201)
1976
43
Malignant struma ovarii. (1004942)
1976
44
Hyperthyroidism due to struma ovarii: demonstration by radioiodine scan. (4740826)
1973
45
Coexisting Brenner tumor and struma ovarii (mature gonadoblastoma). Report of a case. (5760238)
1968
46
Struma ovarii. (5966366)
1966
47
Struma ovarii: report of one case. (13573525)
1958
48
Radioiodine tests in a case of struma ovarii. (13212501)
1954
49
Struma ovarii causing ascites and hydrothorax (Meigs's syndrome). (14808443)
1951
50
METASTASIS OF THYROID TISSUE TO ABDOMINAL ORGANS: WITH SPECIAL CASE REPORT OF A STRUMA OVARII METASTASIZING TO THE OMENTUM. (17866434)
1930

Variations for Struma Ovarii

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Expression for genes affiliated with Struma Ovarii

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Search GEO for disease gene expression data for Struma Ovarii.

Pathways for genes affiliated with Struma Ovarii

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GO Terms for genes affiliated with Struma Ovarii

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Biological processes related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1epithelial tube branching involved in lung morphogenesisGO:00604419.7KRAS, NKX2-1
2thyroid gland developmentGO:00308789.2BRAF, NKX2-1, TG
3visual learningGO:00085429.1BRAF, KRAS
4MAPK cascadeGO:00001658.8BRAF, KRAS, RET
5positive regulation of gene expressionGO:00106288.2BRAF, KRAS, NKX2-1, RET

Sources for Struma Ovarii

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet