MCID: STR021
MIFTS: 37

Struma Ovarii malady

Category: Cancer diseases

Aliases & Classifications for Struma Ovarii

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Aliases & Descriptions for Struma Ovarii:

Name: Struma Ovarii 11 50 39 13 68
 
Struma Ovarii Nos 11

Classifications:



External Ids:

Disease Ontology11 DOID:2640
MeSH39 D013330
SNOMED-CT62 189851000, 24327009
NCIt45 C7468

Summaries for Struma Ovarii

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Wikipedia:71 A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains... more...

MalaCards based summary: Struma Ovarii, also known as struma ovarii nos, is related to hashimoto thyroiditis and malignant struma ovarii. An important gene associated with Struma Ovarii is TG (Thyroglobulin), and among its related pathways are Thyroxine (Thyroid Hormone) Production and Central carbon metabolism in cancer. Affiliated tissues include thyroid, ovary and liver, and related mouse phenotypes are Decreased viability and digestive/alimentary.

Related Diseases for Struma Ovarii

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Diseases in the Struma Ovarii family:

Malignant Struma Ovarii Benign Struma Ovarii

Diseases related to Struma Ovarii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1hashimoto thyroiditis29.1BRAF, RET, TG, TSHR
2malignant struma ovarii12.3
3benign struma ovarii12.3
4thyroiditis10.8
5meige syndrome10.5
6pseudo-meigs syndrome10.5
7hyperthyroidism10.5
8graves' disease10.4
9thyroid cancer10.4
10teratoma10.4
11peritonitis10.3
12transient hypogammaglobulinemia of infancy10.3NKX2-1, TG
13crohn's disease of the esophagus10.3TG, TSHR
14acquired central diabetes insipidus10.3TG, TSHR
15adult teratoma10.2NKX2-1, TG
16papillary carcinoma10.2
17presbyopia10.2TG, TSHR
18hypertelorism, preauricular sinus, punctal pits, and deafness10.2TG, TSHR
19substernal goiter10.2TG, TSHR
20cystadenoma10.2
21adenoma10.2
22glaucomatocyclitic crisis10.2TG, TSHR
23cd3zeta deficiency10.2TG, TSHR
24central nervous system hemangioma10.1TG, TSHR
25hypothyroidism10.1
26cervicitis10.1
27hereditary conventional renal cell carcinoma10.1TG, TSHR
28dysgraphia10.1NKX2-1, TG
29blood group incompatibility10.1TG, TSHR
30dermoid cyst10.0
31cystic teratoma10.0
32adenocarcinoma10.0
33alveoli adenoma10.0TG, TSHR
34pterygium colli mental retardation digital anomalies10.0BRAF, KRAS
35rad51c-related fanconi anemia10.0BRAF, KRAS
36pulmonary venoocclusive disease10.0BRAF, KRAS
37mediastinum teratoma9.9BRAF, KRAS
38fibroma9.9BRAF, KRAS
39radioulnar synostosis9.9BRAF, KRAS
40intermittent proptosis9.9TG, TSHR
41pseudounicornuate uterus9.9KRAS, NKX2-1
42breast cancer9.9
43gonadoblastoma9.9
44goiter9.9
45ovarian cancer9.9
46mucinous ovarian cystadenoma9.9
47ovarian cystadenoma9.9
48cerebritis9.9
49sertoli cell tumor9.9
50pituitary adenoma9.9

Graphical network of the top 20 diseases related to Struma Ovarii:



Diseases related to struma ovarii

Symptoms & Phenotypes for Struma Ovarii

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GenomeRNAi Phenotypes related to Struma Ovarii according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00381-A-19.5BRAF, KRAS, RET

MGI Mouse Phenotypes related to Struma Ovarii according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.0BRAF, KRAS, NKX2-1, RET
2MP:00053978.4BRAF, KRAS, RET, TG, TSHR
3MP:00053868.4BRAF, KRAS, NKX2-1, RET, TSHR
4MP:00020068.3BRAF, KRAS, NKX2-1, RET, TSHR
5MP:00053898.2BRAF, KRAS, NKX2-1, RET, TSHR
6MP:00053888.2BRAF, KRAS, NKX2-1, RET
7MP:00053798.0BRAF, KRAS, NKX2-1, RET, TG, TSHR
8MP:00053788.0BRAF, KRAS, NKX2-1, RET, TG, TSHR
9MP:00053767.9BRAF, KRAS, NKX2-1, RET, TG, TSHR
10MP:00036317.9BRAF, KRAS, NKX2-1, RET, TG, TSHR

Drugs & Therapeutics for Struma Ovarii

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Drugs for Struma Ovarii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Hormones, Hormone Substitutes, and Hormone Antagonists12767
2Hormones13979
3Hormone Antagonists12778

Interventional clinical trials:

idNameStatusNCT IDPhase
1Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer TreatmentCompletedNCT01441154

Search NIH Clinical Center for Struma Ovarii


Cochrane evidence based reviews: struma ovarii

Genetic Tests for Struma Ovarii

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Anatomical Context for Struma Ovarii

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MalaCards organs/tissues related to Struma Ovarii:

36
Thyroid, Ovary, Liver, Bone, Testes, Pituitary, Thymus

Publications for Struma Ovarii

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Articles related to Struma Ovarii:

(show top 50)    (show all 312)
idTitleAuthorsYear
1
Incidental Findings of Intense Radioiodine Uptake in Struma Ovarii and Bilateral Nonlactating Breasts Simultaneously on Postablation (131)I SPECT/CT for Papillary Thyroid Cancer. (27994692)
2016
2
An Unusual Case of Malignant Struma Ovarii Causing Thyrotoxicosis. (27843812)
2016
3
Sincronous malignant struma ovarii and papillary thyroid carcinoma. (27297016)
2016
4
Struma Ovarii With Malignant Transformation and Germline KIT Mutation: A Case Report With Review of the Literature. (27258816)
2016
5
Treatment and follow-up of malignant struma ovarii: Regarding two cases. (27355004)
2016
6
Papillary thyroid cancer located in malignant struma ovarii with omentum metastasis: a case report and review of the literature. (26791568)
2016
7
Incidental diagnosis of struma ovarii through radioiodine whole-body scanning: incremental role of SPECT/CT. (27141138)
2016
8
Follicular Variant of Papillary Carcinoma Arising in Struma Ovarii. (27190936)
2016
9
A Hormonally Active Malignant Struma Ovarii. (27882257)
2016
10
Level of HE4 is Correlated with Diagnosis of Struma Ovarii: A Case Report. (27381498)
2016
11
Metastatic malignant struma ovarii with coexistence of Hashimoto's thyroiditis. (27224256)
2016
12
Synchronous and Metachronous Malignancies After Malignant Struma Ovarii in the SEER Database. (27566096)
2016
13
Management dilemma of thyroid nodules in patients with malignant struma ovarii. (27563566)
2016
14
Novel BRAF and KRAS Mutations in Papillary Thyroid Carcinoma Arising in Struma Ovarii. (26362194)
2015
15
Coexistence of Graves' disease and unilateral functioning Struma ovarii: a case report. (26530865)
2015
16
Usefulness of (131)I-SPECT/CT and (18)F-FDG PET/CT in Evaluating Successful (131)I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii. (25774238)
2015
17
Sonographic and Pathologic Features of Struma Ovarii. (26149143)
2015
18
Coexistence of benign struma ovarii, pseudo-Meigs' syndrome and elevated serum CA 125: Case report and review of the literature. (25789033)
2015
19
Struma ovarii: management and follow-up of a rare ovarian tumour. (25640097)
2015
20
Malignant Struma Ovarii With a Predominant Component of Anaplastic Carcinoma. (26630220)
2015
21
Spinal metastasis from struma ovarii: case report and review of the literature. (25901242)
2015
22
Follicular proliferative lesion arising in struma ovarii. (26018519)
2015
23
Poorly Differentiated Thyroid Carcinoma Arising in Struma Ovarii. (26185700)
2015
24
Struma ovarii complicating pregnancy: a case report. (26411234)
2015
25
Pathology of Struma Ovarii: A Report of 96 Cases. (26374222)
2015
26
Struma Ovarii in Pregnancy: An Uncommon Cause of Hyperthyroidism. (26018691)
2015
27
Late Bone Metastasis of Histologically Bland Struma Ovarii: The Unpredictability of Its Biologic Behavior. (26072948)
2015
28
Hashimoto thyroiditis onset after laparoscopic removal of struma ovarii: an overview to unravel a rare and intriguing finding. (26524822)
2015
29
Struma ovarii accompanied by mature cystic teratoma of the other ovary: A case report and literature review. (26137011)
2015
30
METASTATIC RADIOIODINE AVID STRUMA OVARII ASSOCIATED WITH PSEUDO-MEIGS' SYNDROME. (26721055)
2015
31
Missed Initial Diagnosis of Malignant Struma Ovarii Containing Follicular Thyroid Carcinoma: Metastatic Pulmonary Recurrence 17 yr After Ovariectomy. (26262453)
2015
32
Diffusion-weighted magnetic resonance imaging findings in a patient with struma ovarii. (25272567)
2014
33
Papillary thyroid cancer in a struma ovarii: a report of a rare case. (25402391)
2014
34
131I Therapy Using rhTSH Stimulation and Dosimetry in Metastatic Malignant Struma Ovarii. (24152665)
2014
35
Long-term survival in metastatic malignant struma ovarii treated with oral chemotherapy: A case report. (25364407)
2014
36
Treatment for malignant struma ovarii in the eyes of thyroid surgeons: a case report and study of Chinese cases reported in the literature. (25474425)
2014
37
Coexistence of radioactive iodine-resistant benign struma ovarii with cervical primary papillary cancer of the thyroid: an unusual cause of thyroglobulin-positive radioactive iodine-negative whole-body scans. (24934079)
2014
38
Malignant struma ovarii: a population-level analysis of a large series of 68 patients. (25375817)
2014
39
Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary. (24783110)
2014
40
Struma ovarii. A case report. (26052205)
2014
41
SPECT/CT of Metastatic Struma Ovarii. (23797234)
2014
42
Diagnosis of struma ovarii in a patient with papillary thyroid carcinoma--verification via 124I-PET/US fusion. (24458572)
2014
43
The lack of consensus in management of malignant struma ovarii. (25539066)
2014
44
Late Manifestation of Peritoneal strumosis and widespread functioning lesions in the setting of Struma Ovarii simulating "Highly Differentiated Follicular Carcinoma" (HDFCO). (25537757)
2014
45
Disseminated struma ovarii containing focal anaplastic carcinoma in peritoneal implants: a case report. (25272300)
2014
46
Re: coexistence of struma ovarii and serous cystadenoma of the ovary. (23202789)
2013
47
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review. (23412916)
2013
48
Two cases of malignant struma ovarii with metastasis to pelvic bone. (23391779)
2013
49
Imaging struma ovarii by means of 124I-Na PET/CT. (24068641)
2013
50
Coexistence of malignant struma ovarii and cervical papillary thyroid carcinoma. (24217901)
2013

Variations for Struma Ovarii

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Expression for genes affiliated with Struma Ovarii

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Search GEO for disease gene expression data for Struma Ovarii.

Pathways for genes affiliated with Struma Ovarii

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GO Terms for genes affiliated with Struma Ovarii

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Biological processes related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1epithelial tube branching involved in lung morphogenesisGO:006044110.2KRAS, NKX2-1
2MAPK cascadeGO:00001659.2BRAF, KRAS, RET
3thyroid gland developmentGO:00308789.2BRAF, NKX2-1, TG
4visual learningGO:00085429.1BRAF, KRAS
5positive regulation of gene expressionGO:00106288.6BRAF, KRAS, NKX2-1, RET

Sources for Struma Ovarii

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet