Summaries for Struma Ovarii

About this section


Wikipedia:63 A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains... more...

MalaCards based summary: Struma Ovarii, also known as struma ovarii nos, is related to thyroiditis and teratoma. An important gene associated with Struma Ovarii is TG (thyroglobulin), and among its related pathways are Insulin secretion and Thyroxine (Thyroid Hormone) Production. The compounds propylthiouracil and 125i have been mentioned in the context of this disorder. Affiliated tissues include thyroid, ovary and liver, and related mouse phenotypes are digestive/alimentary and reproductive system.

Aliases & Classifications for Struma Ovarii

About this section
Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 55SNOMED-CT, 33MeSH, 38NCIt
See all sources

Struma Ovarii, Aliases & Descriptions:

Name: Struma Ovarii 9 11 43 60
 
Struma Ovarii Nos 9


External Ids:

Disease Ontology9 DOID:2640
MeSH33 D013330
SNOMED-CT55 189851000, 24327009
NCIt38 C7468

Related Diseases for Struma Ovarii

About this section

Diseases in the Struma Ovarii family:

Malignant Struma Ovarii Benign Struma Ovarii

Diseases related to Struma Ovarii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1thyroiditis32.0TG, TSHR
2teratoma31.4NKX2-1, TG
3hyperthyroidism31.4TSHR, TG
4graves' disease31.2NKX2-1, TSHR, TG
5thyrotoxicosis30.9TSHR, TG
6hypothyroidism30.8NKX2-1, TSHR, TG
7thyroid cancer30.3NKX2-1, RET, TSHR, BRAF, TG
8breast cancer29.9NKX2-1, HNF1A, MUC16
9hashimoto thyroiditis29.9TG, BRAF, TSHR, RET
10papillary carcinoma29.8RET, TSHR, MUC16, BRAF, TG, NKX2-1
11adenoma29.7TG, BRAF, TSHR, RET, HNF1A, NKX2-1
12goiter29.6TG, BRAF, TSHR, RET, NKX2-1
13malignant struma ovarii11.2
14pseudo-meigs syndrome10.8
15benign struma ovarii10.8
16peritonitis10.6
17cystadenoma10.6
18cervicitis10.5
19bronchogenic cyst10.4MUC16
20adenocarcinoma10.4
21autoimmune thyroiditis10.3
22mucinous ovarian cystadenoma10.3
23gonadoblastoma10.3
24cerebritis10.3
25sertoli cell tumor10.3
26cystadenofibroma10.3
27cystic teratoma10.3
28ovarian cystadenoma10.3
29pituitary adenoma10.3
30blindness10.3
31myxedema10.3TSHR, TG
32subacute thyroiditis10.2TSHR, TG
33toxic diffuse goiter10.2TG, TSHR
34papillary adenocarcinoma10.2MUC16, NKX2-1
35endemic goiter10.2TG, TSHR
36nontoxic goiter10.2TSHR, TG
37multinodular goiter10.2TG, TSHR
38abrikosov's tumor10.2NKX2-1, MUC16
39thyroid carcinoma, follicular10.2TG, TSHR
40factor vii deficiency10.2TG, MUC16
41malignant pleural mesothelioma10.2MUC16, NKX2-1
42endometrial cancer10.2MUC16, BRAF
43mesothelioma, somatic10.1NKX2-1, MUC16
44mesothelioma10.1NKX2-1, MUC16
45multiple endocrine neoplasia10.1TG, RET
46hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia10.1NKX2-1, TSHR, TG
47congenital hypothyroidism10.1NKX2-1, TSHR, TG
48paraganglioma10.0TG, RET
49hemangioma10.0RET, NKX2-1
50lung cancer susceptibility 310.0NKX2-1, MUC16, BRAF

Graphical network of the top 20 diseases related to Struma Ovarii:



Diseases related to struma ovarii

Symptoms for Struma Ovarii

About this section

Drugs & Therapeutics for Struma Ovarii

About this section

Drug clinical trials:

Search ClinicalTrials for Struma Ovarii

Search NIH Clinical Center for Struma Ovarii

Genetic Tests for Struma Ovarii

About this section

Anatomical Context for Struma Ovarii

About this section

MalaCards organs/tissues related to Struma Ovarii:

31
Thyroid, Ovary, Liver, Eye, Bone, Thymus, Colon, Breast, Testes, Pituitary

Animal Models for Struma Ovarii or affiliated genes

About this section

MGI Mouse Phenotypes related to Struma Ovarii:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.0BRAF, RET, HNF1A, NKX2-1
2MP:00053897.7BRAF, TSHR, RET, HNF1A, NKX2-1
3MP:00053867.6NKX2-1, HNF1A, RET, TSHR, BRAF
4MP:00107687.6NKX2-1, HNF1A, RET, TSHR, BRAF
5MP:00036317.5TG, BRAF, TSHR, RET, NKX2-1
6MP:00053797.4NKX2-1, HNF1A, RET, TSHR, BRAF, TG
7MP:00053787.4TG, BRAF, TSHR, RET, HNF1A, NKX2-1
8MP:00053767.4TG, BRAF, TSHR, RET, HNF1A, NKX2-1

Publications for Struma Ovarii

About this section

Articles related to Struma Ovarii:

(show top 50)    (show all 282)
idTitleAuthorsYear
1
Spinal metastasis from struma ovarii: case report and review of the literature. (25901242)
2015
2
Diffusion-weighted magnetic resonance imaging findings in a patient with struma ovarii. (25272567)
2014
3
Papillary thyroid cancer in a struma ovarii: a report of a rare case. (25402391)
2014
4
131I Therapy Using rhTSH Stimulation and Dosimetry in Metastatic Malignant Struma Ovarii. (24152665)
2014
5
Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary. (24783110)
2014
6
Tall Cell Variant Papillary Thyroid Carcinoma Arising from Struma Ovarii. (24246339)
2013
7
Incidental finding of struma ovarii. (22770863)
2013
8
Re: coexistence of struma ovarii and serous cystadenoma of the ovary. (23202789)
2013
9
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review. (23412916)
2013
10
Coexistence of Graves' disease, papillary thyroid carcinoma and unilateral benign struma ovarii: case report and review of the literature. (23806737)
2013
11
Optimal surgical management of well-differentiated thyroid cancer arising in struma ovarii: a series of 4 patients and a review of 53 reported cases. (22181336)
2012
12
Thyroid-type solid cell nests in struma ovarii. (20034983)
2011
13
Role of the otolaryngologist in the treatment of struma ovarii. (20013844)
2010
14
Severe ophthalmopathy developing after treatment of coexisting malignant struma ovarii and Graves' disease. (19772400)
2009
15
Struma ovarii and peritoneal strumosis with thyrotoxicosis. (19265502)
2009
16
Histologically bland "extremely well differentiated" thyroid carcinomas arising in struma ovarii can recur and metastasize. (19620939)
2009
17
Struma ovarii: CT findings. (18214583)
2008
18
Struma Ovarii with a focus of follicular variant of papillary thyroid cancer: a case report. (18646677)
2008
19
A case of metastatic struma ovarii treated with 131I therapy: focus on preservation of fertility and selected review of the literature. (18584410)
2008
20
Struma ovarii associated with hyperthyroidism, elevated CA 125 and pseudo-Meigs syndrome may mimic advanced ovarian cancer. (18618418)
2008
21
Papillary carcinoma in struma ovarii: an unusual presentation. (18689908)
2008
22
Struma ovarii with pseudo-Meigs' syndrome and elevated CA125 levels. (17365481)
2007
23
Malignant struma ovarii: a case report and review of the literature. (15166470)
2004
24
Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report. (15262148)
2004
25
Struma ovarii: US and CT findings. (14527060)
2003
26
Benign and malignant struma ovarii: report of three cases and review of the literature. (17577264)
2002
27
Struma ovarii: a rare benign pathology which may erroneously suggest malignancy. (11703211)
2001
28
Malignant struma ovarii with thyrotoxicosis. (11520159)
2001
29
Coexistence of Graves' disease and struma ovarii: case report and literature review. (11456276)
2001
30
Cystic struma ovarii: imaging findings. (10864077)
2000
31
Sonographic and clinical characteristics of struma ovarii. (11127011)
2000
32
Struma ovarii presenting as acute pseudo-Meigs syndrome with an elevated CA 125 level. (8883774)
1996
33
Struma ovarii simulating ovarian tumors of other types. A report of 30 cases. (7802134)
1995
34
Struma ovarii with pseudo-Meigs' syndrome: report of a case and review of the literature. (7958166)
1994
35
Limitations of CA125 in the preoperative evaluation of a pelvic mass: struma ovarii and ascites. (8216132)
1993
36
Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases. (8253550)
1993
37
Metastasis of malignant struma ovarii to the cranial vault during pregnancy. (8413886)
1993
38
Malignant follicular variant of papillary struma ovarii. (2076892)
1990
39
Metastatic malignant struma ovarii presenting as paraparesis from a spinal metastasis. (2738669)
1989
40
Malignant struma ovarii. Light and electron microscopic study. (6821820)
1983
41
Thyroglobulin in struma ovarii. (682610)
1978
42
Ascites and hydrothorax in association with struma ovarii. (943201)
1976
43
Malignant struma ovarii. (1004942)
1976
44
Ovarian teratoma (struma ovarii) (ovarian goiter). (13783814)
1961
45
Struma ovarii: report of one case. (13573525)
1958
46
Struma ovarii; demonstration of both pathologic change and physiologic activity; report of four cases. (13431133)
1957
47
Struma ovarii causing ascites and hydrothorax (Meigs's syndrome). (14808443)
1951
48
Struma ovarii accompanied by thyrectoxicosis. (18857232)
1948
49
Struma Ovarii. (19989482)
1933
50
METASTASIS OF THYROID TISSUE TO ABDOMINAL ORGANS: WITH SPECIAL CASE REPORT OF A STRUMA OVARII METASTASIZING TO THE OMENTUM. (17866434)
1930

Variations for Struma Ovarii

About this section

Expression for genes affiliated with Struma Ovarii

About this section
Search GEO for disease gene expression data for Struma Ovarii.

Pathways for genes affiliated with Struma Ovarii

About this section

Pathways related to Struma Ovarii according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6TSHR, TG
29.6TSHR, TG
39.5HNF1A, NKX2-1
49.0RET, BRAF
5
Show member pathways
9.0RET, BRAF

Compounds for genes affiliated with Struma Ovarii

About this section

Compounds related to Struma Ovarii according to GeneCards Suite gene sharing:

(show all 49)
idCompoundScoreTop Affiliating Genes
1propylthiouracil43 2 1212.0TSHR, TG
2125i4310.0TG, TSHR
3methimazole43 2 1212.0TSHR, TG
4b 723439.9NKX2-1, MUC16
5hematoxylin439.7NKX2-1, MUC16
6triiodothyronine439.7TSHR, TG
7ganciclovir43 1210.6RET, TG
8depsipeptide439.6BRAF, TG
9prednisolone43 28 1211.5TSHR, MUC16, TG
10sialic acid439.5TSHR, MUC16, TG
11succinate439.5TSHR, RET
12glutamine439.4TG, TSHR, HNF1A
13regorafenib49 1210.4BRAF, RET
14thymidine43 2410.4TG, TSHR, HNF1A
15sorafenib43 49 1211.3RET, BRAF
16creatinine439.3HNF1A, MUC16, TG
17iodine43 2410.3TSHR, BRAF, TG
18gold439.2TG, BRAF, MUC16
19forskolin43 49 1211.1BRAF, TSHR, NKX2-1
20leucine439.1TSHR, RET, HNF1A
21ribonucleic acid439.0NKX2-1, RET, TSHR, TG
22agar439.0TG, BRAF, RET
23cisplatin43 49 59 1212.0MUC16, BRAF, TG
24adenine43 24 1211.0BRAF, TSHR, RET
25testosterone43 59 24 1212.0TG, MUC16, RET
26valine439.0RET, TSHR, BRAF
2712-o-tetradecanoylphorbol 13-acetate438.9RET, TSHR, BRAF
28steroid438.9NKX2-1, HNF1A, MUC16
29iodide43 249.9TG, BRAF, TSHR, NKX2-1
30dexamethasone43 49 28 1211.7MUC16, HNF1A, NKX2-1
31progesterone43 28 59 24 1212.7BRAF, MUC16, TSHR, NKX2-1
32aspartate438.6RET, TSHR, BRAF, TG
33arginine438.6TG, BRAF, TSHR, RET
34phosphatidylinositol438.6RET, TSHR, BRAF
35cyclic amp43 249.6BRAF, TSHR, RET, NKX2-1
36alanine438.6RET, TSHR, BRAF, TG
37glucose438.5HNF1A, TSHR, MUC16, BRAF
38phenylalanine438.5BRAF, TSHR, RET, HNF1A
39lipid438.4BRAF, TSHR, RET, HNF1A
40sodium43 249.3TG, BRAF, MUC16, TSHR, NKX2-1
41sodium iodide438.2NKX2-1, RET, TSHR, BRAF, TG
42vegf438.1TG, BRAF, MUC16, TSHR, RET
43oligonucleotide438.1BRAF, TSHR, RET, HNF1A, NKX2-1
44threonine438.1BRAF, MUC16, TSHR, RET, NKX2-1
45estrogen437.8TG, BRAF, MUC16, TSHR, HNF1A, NKX2-1
46paraffin437.7TG, BRAF, MUC16, TSHR, RET, NKX2-1
47retinoic acid43 248.7TG, BRAF, TSHR, RET, HNF1A, NKX2-1
48serine437.7TG, BRAF, MUC16, TSHR, RET, NKX2-1
49tyrosine437.2TG, BRAF, MUC16, TSHR, RET, HNF1A

GO Terms for genes affiliated with Struma Ovarii

About this section

Cellular components related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor complexGO:00432359.4RET, TSHR

Biological processes related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1thyroid gland developmentGO:00308789.4NKX2-1, TG
2positive regulation of transcription, DNA-templatedGO:00458938.9NKX2-1, HNF1A, RET

Molecular functions related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055157.1NKX2-1, HNF1A, RET, TSHR, MUC16, BRAF

Products for genes affiliated with Struma Ovarii

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Struma Ovarii

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet