Aliases & Classifications for Struma Ovarii

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 61UMLS, 56SNOMED-CT, 33MeSH, 39NCIt
See all sources

Aliases & Descriptions for Struma Ovarii:

Name: Struma Ovarii 8 10 44 61
 
Struma Ovarii Nos 8


External Ids:

Disease Ontology8 DOID:2640
MeSH33 D013330
SNOMED-CT56 189851000, 24327009
NCIt39 C7468

Summaries for Struma Ovarii

About this section
Wikipedia:64 A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains... more...

MalaCards based summary: Struma Ovarii, also known as struma ovarii nos, is related to thyroiditis and teratoma. An important gene associated with Struma Ovarii is TG (thyroglobulin), and among its related pathways are Insulin secretion and Thyroxine (Thyroid Hormone) Production. The compounds propylthiouracil and 125i have been mentioned in the context of this disorder. Affiliated tissues include thyroid, ovary and liver, and related mouse phenotypes are digestive/alimentary and reproductive system.

Related Diseases for Struma Ovarii

About this section

Diseases in the Struma Ovarii family:

Malignant Struma Ovarii Benign Struma Ovarii

Diseases related to Struma Ovarii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1thyroiditis32.0TG, TSHR
2teratoma31.4NKX2-1, TG
3hyperthyroidism31.4TSHR, TG
4graves' disease31.2NKX2-1, TSHR, TG
5thyrotoxicosis30.9TSHR, TG
6hypothyroidism30.8NKX2-1, TSHR, TG
7thyroid cancer30.3NKX2-1, RET, TSHR, BRAF, TG
8breast cancer29.9NKX2-1, HNF1A, MUC16
9hashimoto thyroiditis29.9TG, BRAF, TSHR, RET
10papillary carcinoma29.8RET, TSHR, MUC16, BRAF, TG, NKX2-1
11adenoma29.7TG, BRAF, TSHR, RET, HNF1A, NKX2-1
12goiter29.6TG, BRAF, TSHR, RET, NKX2-1
13malignant struma ovarii11.2
14pseudo-meigs syndrome10.8
15benign struma ovarii10.8
16peritonitis10.6
17cystadenoma10.6
18cervicitis10.5
19bronchogenic cyst10.4MUC16
20adenocarcinoma10.4
21autoimmune thyroiditis10.3
22mucinous ovarian cystadenoma10.3
23gonadoblastoma10.3
24cerebritis10.3
25sertoli cell tumor10.3
26cystadenofibroma10.3
27cystic teratoma10.3
28ovarian cystadenoma10.3
29pituitary adenoma10.3
30blindness10.3
31myxedema10.3TSHR, TG
32subacute thyroiditis10.2TSHR, TG
33toxic diffuse goiter10.2TG, TSHR
34papillary adenocarcinoma10.2MUC16, NKX2-1
35endemic goiter10.2TG, TSHR
36nontoxic goiter10.2TSHR, TG
37multinodular goiter10.2TG, TSHR
38abrikosov's tumor10.2NKX2-1, MUC16
39thyroid carcinoma, follicular10.2TG, TSHR
40factor vii deficiency10.2TG, MUC16
41malignant pleural mesothelioma10.2MUC16, NKX2-1
42endometrial cancer10.2MUC16, BRAF
43mesothelioma, somatic10.1NKX2-1, MUC16
44mesothelioma10.1NKX2-1, MUC16
45multiple endocrine neoplasia10.1TG, RET
46hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia10.1NKX2-1, TSHR, TG
47congenital hypothyroidism10.1NKX2-1, TSHR, TG
48paraganglioma10.0TG, RET
49hemangioma10.0RET, NKX2-1
50lung cancer susceptibility 310.0NKX2-1, MUC16, BRAF

Graphical network of the top 20 diseases related to Struma Ovarii:



Diseases related to struma ovarii

Symptoms for Struma Ovarii

About this section

Drugs & Therapeutics for Struma Ovarii

About this section

Drug clinical trials:

Search ClinicalTrials for Struma Ovarii

Search NIH Clinical Center for Struma Ovarii

Genetic Tests for Struma Ovarii

About this section

Anatomical Context for Struma Ovarii

About this section

MalaCards organs/tissues related to Struma Ovarii:

31
Thyroid, Ovary, Liver, Eye, Bone, Thymus, Colon, Breast, Testes, Pituitary

Animal Models for Struma Ovarii or affiliated genes

About this section

MGI Mouse Phenotypes related to Struma Ovarii:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.0BRAF, RET, HNF1A, NKX2-1
2MP:00053897.7BRAF, TSHR, RET, HNF1A, NKX2-1
3MP:00053867.6NKX2-1, HNF1A, RET, TSHR, BRAF
4MP:00107687.6NKX2-1, HNF1A, RET, TSHR, BRAF
5MP:00036317.5TG, BRAF, TSHR, RET, NKX2-1
6MP:00053797.4NKX2-1, HNF1A, RET, TSHR, BRAF, TG
7MP:00053787.4TG, BRAF, TSHR, RET, HNF1A, NKX2-1
8MP:00053767.4TG, BRAF, TSHR, RET, HNF1A, NKX2-1

Publications for Struma Ovarii

About this section

Articles related to Struma Ovarii:

(show top 50)    (show all 282)
idTitleAuthorsYear
1
Spinal metastasis from struma ovarii: case report and review of the literature. (25901242)
2015
2
Diffusion-weighted magnetic resonance imaging findings in a patient with struma ovarii. (25272567)
2014
3
Papillary thyroid cancer in a struma ovarii: a report of a rare case. (25402391)
2014
4
131I Therapy Using rhTSH Stimulation and Dosimetry in Metastatic Malignant Struma Ovarii. (24152665)
2014
5
Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary. (24783110)
2014
6
Tall Cell Variant Papillary Thyroid Carcinoma Arising from Struma Ovarii. (24246339)
2013
7
Incidental finding of struma ovarii. (22770863)
2013
8
Re: coexistence of struma ovarii and serous cystadenoma of the ovary. (23202789)
2013
9
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review. (23412916)
2013
10
Coexistence of Graves' disease, papillary thyroid carcinoma and unilateral benign struma ovarii: case report and review of the literature. (23806737)
2013
11
Optimal surgical management of well-differentiated thyroid cancer arising in struma ovarii: a series of 4 patients and a review of 53 reported cases. (22181336)
2012
12
Thyroid-type solid cell nests in struma ovarii. (20034983)
2011
13
Role of the otolaryngologist in the treatment of struma ovarii. (20013844)
2010
14
Severe ophthalmopathy developing after treatment of coexisting malignant struma ovarii and Graves' disease. (19772400)
2009
15
Struma ovarii and peritoneal strumosis with thyrotoxicosis. (19265502)
2009
16
Histologically bland "extremely well differentiated" thyroid carcinomas arising in struma ovarii can recur and metastasize. (19620939)
2009
17
Struma ovarii: CT findings. (18214583)
2008
18
Struma Ovarii with a focus of follicular variant of papillary thyroid cancer: a case report. (18646677)
2008
19
A case of metastatic struma ovarii treated with 131I therapy: focus on preservation of fertility and selected review of the literature. (18584410)
2008
20
Struma ovarii associated with hyperthyroidism, elevated CA 125 and pseudo-Meigs syndrome may mimic advanced ovarian cancer. (18618418)
2008
21
Papillary carcinoma in struma ovarii: an unusual presentation. (18689908)
2008
22
Struma ovarii with pseudo-Meigs' syndrome and elevated CA125 levels. (17365481)
2007
23
Malignant struma ovarii: a case report and review of the literature. (15166470)
2004
24
Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report. (15262148)
2004
25
Struma ovarii: US and CT findings. (14527060)
2003
26
Benign and malignant struma ovarii: report of three cases and review of the literature. (17577264)
2002
27
Struma ovarii: a rare benign pathology which may erroneously suggest malignancy. (11703211)
2001
28
Malignant struma ovarii with thyrotoxicosis. (11520159)
2001
29
Coexistence of Graves' disease and struma ovarii: case report and literature review. (11456276)
2001
30
Cystic struma ovarii: imaging findings. (10864077)
2000
31
Sonographic and clinical characteristics of struma ovarii. (11127011)
2000
32
Struma ovarii presenting as acute pseudo-Meigs syndrome with an elevated CA 125 level. (8883774)
1996
33
Struma ovarii simulating ovarian tumors of other types. A report of 30 cases. (7802134)
1995
34
Struma ovarii with pseudo-Meigs' syndrome: report of a case and review of the literature. (7958166)
1994
35
Limitations of CA125 in the preoperative evaluation of a pelvic mass: struma ovarii and ascites. (8216132)
1993
36
Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases. (8253550)
1993
37
Metastasis of malignant struma ovarii to the cranial vault during pregnancy. (8413886)
1993
38
Malignant follicular variant of papillary struma ovarii. (2076892)
1990
39
Metastatic malignant struma ovarii presenting as paraparesis from a spinal metastasis. (2738669)
1989
40
Malignant struma ovarii. Light and electron microscopic study. (6821820)
1983
41
Thyroglobulin in struma ovarii. (682610)
1978
42
Ascites and hydrothorax in association with struma ovarii. (943201)
1976
43
Malignant struma ovarii. (1004942)
1976
44
Ovarian teratoma (struma ovarii) (ovarian goiter). (13783814)
1961
45
Struma ovarii: report of one case. (13573525)
1958
46
Struma ovarii; demonstration of both pathologic change and physiologic activity; report of four cases. (13431133)
1957
47
Struma ovarii causing ascites and hydrothorax (Meigs's syndrome). (14808443)
1951
48
Struma ovarii accompanied by thyrectoxicosis. (18857232)
1948
49
Struma Ovarii. (19989482)
1933
50
METASTASIS OF THYROID TISSUE TO ABDOMINAL ORGANS: WITH SPECIAL CASE REPORT OF A STRUMA OVARII METASTASIZING TO THE OMENTUM. (17866434)
1930

Variations for Struma Ovarii

About this section

Expression for genes affiliated with Struma Ovarii

About this section
Search GEO for disease gene expression data for Struma Ovarii.

Pathways for genes affiliated with Struma Ovarii

About this section

Pathways related to Struma Ovarii according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6TSHR, TG
29.6TSHR, TG
39.5HNF1A, NKX2-1
49.0RET, BRAF
5
Show member pathways
9.0RET, BRAF

Compounds for genes affiliated with Struma Ovarii

About this section

Compounds related to Struma Ovarii according to GeneCards Suite gene sharing:

(show all 49)
idCompoundScoreTop Affiliating Genes
1propylthiouracil44 1 1112.0TSHR, TG
2125i4410.0TSHR, TG
3methimazole44 1 1112.0TSHR, TG
4b 723449.9MUC16, NKX2-1
5hematoxylin449.7NKX2-1, MUC16
6triiodothyronine449.7TSHR, TG
7ganciclovir44 1110.6TG, RET
8depsipeptide449.6BRAF, TG
9prednisolone44 28 1111.5MUC16, TSHR, TG
10sialic acid449.5MUC16, TSHR, TG
11succinate449.5TSHR, RET
12glutamine449.4HNF1A, TSHR, TG
13regorafenib50 1110.4RET, BRAF
14thymidine44 2410.4HNF1A, TSHR, TG
15sorafenib44 50 1111.3BRAF, RET
16creatinine449.3TG, MUC16, HNF1A
17iodine44 2410.3TG, BRAF, TSHR
18gold449.2MUC16, TG, BRAF
19forskolin44 50 1111.1TSHR, BRAF, NKX2-1
20leucine449.1HNF1A, RET, TSHR
21ribonucleic acid449.0NKX2-1, TG, TSHR, RET
22agar449.0RET, TG, BRAF
23cisplatin44 50 60 1112.0MUC16, BRAF, TG
24adenine44 24 1111.0TSHR, RET, BRAF
25testosterone44 60 24 1112.0RET, MUC16, TG
26valine449.0RET, BRAF, TSHR
2712-o-tetradecanoylphorbol 13-acetate448.9RET, BRAF, TSHR
28steroid448.9NKX2-1, MUC16, HNF1A
29iodide44 249.9TSHR, BRAF, TG, NKX2-1
30dexamethasone44 50 28 1111.7HNF1A, MUC16, NKX2-1
31progesterone44 28 60 24 1112.7BRAF, TSHR, MUC16, NKX2-1
32aspartate448.6TG, TSHR, RET, BRAF
33arginine448.6BRAF, TSHR, TG, RET
34phosphatidylinositol448.6TSHR, RET, BRAF
35cyclic amp44 249.6BRAF, TSHR, RET, NKX2-1
36alanine448.6TG, TSHR, BRAF, RET
37glucose448.5HNF1A, TSHR, MUC16, BRAF
38phenylalanine448.5HNF1A, RET, BRAF, TSHR
39lipid448.4BRAF, RET, TSHR, HNF1A
40sodium44 249.3TG, NKX2-1, TSHR, MUC16, BRAF
41sodium iodide448.2TG, BRAF, TSHR, RET, NKX2-1
42vegf448.1TG, RET, MUC16, TSHR, BRAF
43oligonucleotide448.1RET, HNF1A, TSHR, BRAF, NKX2-1
44threonine448.1MUC16, NKX2-1, BRAF, TSHR, RET
45estrogen447.8TG, BRAF, TSHR, HNF1A, NKX2-1, MUC16
46paraffin447.7NKX2-1, RET, TSHR, MUC16, BRAF, TG
47retinoic acid44 248.7TSHR, BRAF, TG, RET, HNF1A, NKX2-1
48serine447.7TSHR, RET, NKX2-1, MUC16, BRAF, TG
49tyrosine447.2BRAF, NKX2-1, HNF1A, RET, TSHR, MUC16

GO Terms for genes affiliated with Struma Ovarii

About this section

Cellular components related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor complexGO:00432359.4RET, TSHR

Biological processes related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1thyroid gland developmentGO:00308789.4NKX2-1, TG
2positive regulation of transcription, DNA-templatedGO:00458938.9NKX2-1, HNF1A, RET

Molecular functions related to Struma Ovarii according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055157.1NKX2-1, HNF1A, RET, TSHR, MUC16, BRAF

Sources for Struma Ovarii

About this section
2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet