Subacute Bacterial Endocarditis malady

Wikipedia: Subacute bacterial endocarditis (also called endocarditis lenta) is a type of endocarditis (more...⁴⁴ more...

MalaCards: Subacute Bacterial Endocarditis, also known as subacute bacterial endocarditis (disorder), is related to endocarditis and wegener's granulomatosis. An important gene associated with Subacute Bacterial Endocarditis is PRTN3 (proteinase 3). The drug penicillin g procaine and the compound superoxide have been mentioned in the context of this disorder.

Aliases & Descriptions:

subacute bacterial endocarditis 6 32 43 subacute bacterial endocarditis (disorder) 6 sbe - subacute bacterial endocarditis 6

subacute endocarditis, lenta 6 subacute endocarditis 43 endocarditis lenta 6

Diseases related to subacute bacterial endocarditis by text searches and GeneDecks gene sharing:

(show all 17)

id	Related Disease	Score	Top Affiliating Genes
1	endocarditis	31.2	CFP, DNAJA2, PRTN3
2	wegener's granulomatosis	12.6	DNAJA2, PRTN3
3	hematuria	12.3	PRTN3, CFP
4	iga glomerulonephritis	12.3	CFP, PRTN3
5	factor v leiden thrombophilia	12.2	PRTN3, CFP
6	proteinuria	12.2	CFP, PRTN3
7	vasculitis	12.2	CFP, PRTN3
8	gout	12.1	CFP, PRTN3
9	systemic lupus erythematosus	12.0	PRTN3, CFP
10	hypersensitivity reaction type ii disease	12.0	CFP, PRTN3
11	nephritis	11.9	CFP, PRTN3
12	infective endocarditis	11.8	PRTN3, DNAJA2, CFP
13	cystic fibrosis	11.8	CFP, DNAJA2, PRTN3
14	glomerulonephritis	11.7	CFP, PRTN3
15	arthritis	11.6	PRTN3, DNAJA2, CFP
16	microscopic polyangiitis	7.6
17	nephrotic syndrome	7.6

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 penicillin g procaine

Articles related to subacute bacterial endocarditis:

id	Title	Authors	Year	Affiliating Genes
1	Anti-MPO-ANCA-positive microscopic polyangiitis following subacute bacterial endocarditis. (11771532)	Hellmich B.... Schatz H.	2001	PRTN3
2	The presence of cytoplasmic antineutrophil cytoplasmic antibodies (C-ANCA) in the course of subacute bacterial endocarditis with glomerular involvement, coincidence or association? (9491280)	Subra J.F.... Chevailler A.	1998	PRTN3
3	Nephrotic syndrome associated with subacute bacterial endocarditis (SBE): a case report. (7570680)	Yamauchi F.... Koide S.	1994	CFP

Genes related to subacute bacterial endocarditis according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	PRTN3	proteinase 3	11.0	Publications
2	CFP	complement factor properdin	11.0	Publications
3	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	11.0

Compounds related to subacute bacterial endocarditis according to GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	superoxide32 18	10.0	CFP, PRTN3

Cellular components related to subacute bacterial endocarditis according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	extracellular matrix	GO:031012	9.0	CFP, PRTN3

Biological processes related to subacute bacterial endocarditis according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of cell proliferation	GO:008284	9.3	DNAJA2, PRTN3