MCID: SBS005
MIFTS: 28

Substance-Induced Psychosis malady

Categories: Mental diseases

Aliases & Classifications for Substance-Induced Psychosis

Aliases & Descriptions for Substance-Induced Psychosis:

Name: Substance-Induced Psychosis 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:8646
ICD9CM 35 293.89
UMLS 69 C0154334

Summaries for Substance-Induced Psychosis

MalaCards based summary : Substance-Induced Psychosis is related to polyneuropathy and antisocial personality disorder. An important gene associated with Substance-Induced Psychosis is GLYAT (Glycine-N-Acyltransferase), and among its related pathways/superpathways are Monoamine GPCRs and Serotonergic synapse. The drugs Aripiprazole and Dexmedetomidine have been mentioned in the context of this disorder. Affiliated tissues include testes and brain.

Wikipedia : 71 Substance-induced psychosis (commonly known as toxic psychosis) is a form of substance use disorder... more...

Related Diseases for Substance-Induced Psychosis

Graphical network of the top 20 diseases related to Substance-Induced Psychosis:



Diseases related to Substance-Induced Psychosis

Symptoms & Phenotypes for Substance-Induced Psychosis

Drugs & Therapeutics for Substance-Induced Psychosis

Drugs for Substance-Induced Psychosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
2
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
3
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
4 Tranquilizing Agents Phase 4
5 Psychotropic Drugs Phase 4
6 Antipsychotic Agents Phase 4
7 Central Nervous System Depressants Phase 4
8 Analgesics Phase 4
9 N-Methylaspartate Phase 4
10 Adrenergic Agents Phase 4
11 Adrenergic Agonists Phase 4
12 Adrenergic alpha-2 Receptor Agonists Phase 4
13 Adrenergic alpha-Agonists Phase 4
14 Neurotransmitter Agents Phase 4
15 Analgesics, Non-Narcotic Phase 4
16 Anesthetics Phase 4
17 Anesthetics, Dissociative Phase 4
18 Anesthetics, General Phase 4
19 Anesthetics, Intravenous Phase 4
20 Peripheral Nervous System Agents Phase 4
21 Hypnotics and Sedatives Phase 4
22 Excitatory Amino Acid Antagonists Phase 4
23 Excitatory Amino Acids Phase 4
24 Aspartic Acid Nutraceutical Phase 4
25
Ethanol Approved Phase 2 64-17-5 702
26 Piracetam Approved Phase 2 7491-74-9
27 Neuroprotective Agents Phase 2
28 Nootropic Agents Phase 2
29 Etiracetam Phase 2
30 Anticonvulsants Phase 2
31 Protective Agents Phase 2
32
Dopamine Approved 51-61-6, 62-31-7 681
33
Cocaine Approved, Illicit 50-36-2 5760 446220
34
Modafinil Approved, Investigational 68693-11-8 4236
35
Armodafinil Approved, Investigational 112111-43-0
36 Neurotransmitter Uptake Inhibitors
37 Cytochrome P-450 CYP3A Inducers
38 Anesthetics, Local
39 Dopamine Agents
40 Vasoconstrictor Agents
41 Dopamine Uptake Inhibitors
42 Wakefulness-Promoting Agents
43 Central Nervous System Stimulants

Interventional clinical trials:


id Name Status NCT ID Phase
1 Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole Unknown status NCT01155544 Phase 4
2 Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids Completed NCT00205712 Phase 4
3 Levetiracetam for the Treatment of Alcohol Dependence and Anxiety Completed NCT00141115 Phase 2
4 AIMHI NT Relapse Prevention Trial Unknown status NCT00192582
5 Prevention of Weight Gain in Early Psychoses Completed NCT01075295
6 Lifestyle Intervention for Diabetes and Weight Management in Psychosis Completed NCT01828931
7 Modafinil, Sleep, and Cognition in Cocaine Dependence Completed NCT00582491
8 Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3 Enrolling by invitation NCT03048552

Search NIH Clinical Center for Substance-Induced Psychosis

Genetic Tests for Substance-Induced Psychosis

Anatomical Context for Substance-Induced Psychosis

MalaCards organs/tissues related to Substance-Induced Psychosis:

39
Testes, Brain

Publications for Substance-Induced Psychosis

Articles related to Substance-Induced Psychosis:

(show all 21)
id Title Authors Year
1
Characterization of white matter integrity deficits in cocaine-dependent individuals with substance-induced psychosis compared with non-psychotic cocaine users. ( 26833821 )
2016
2
Subcortical grey matter alterations in cocaine dependent individuals with substance-induced psychosis compared to non-psychotic cocaine users. ( 27499362 )
2016
3
Structural and metabolic differentiation between bipolar disorder with psychosis and substance-induced psychosis: An integrated MRI/PET study. ( 28049086 )
2016
4
The epidemiology and progression time from transient to permanent psychiatric disorders of substance-induced psychosis in Taiwan. ( 25841087 )
2015
5
Psychopathology in Substance Use Disorder Patients with and without Substance-Induced Psychosis. ( 26417473 )
2015
6
Comparison of history of adolescents with substance-induced psychosis, early onset schizophrenia and substance use disorders. ( 25520226 )
2014
7
Treatment of refractory substance-induced psychosis in adolescent males with a genetic predisposition to mental illness. ( 24762642 )
2014
8
Brain metabolism in substance-induced psychosis and schizophrenia: a preliminary PET study. ( 25471704 )
2014
9
Treated incidence and baseline characteristics of substance induced psychosis in a Norwegian catchment area. ( 24279887 )
2013
10
The risk of substance-induced psychosis converting to schizophrenia varies with substance used and patient age. ( 23708315 )
2013
11
Forensic considerations of substance-induced psychosis. ( 23771929 )
2013
12
A prospective 2-year study of emergency department patients with early-phase primary psychosis or substance-induced psychosis. ( 21454918 )
2011
13
A comparison of the symptoms and short-term clinical course in inpatients with substance-induced psychosis and primary psychosis. ( 20864293 )
2011
14
Developing and testing adaptive treatment strategies using substance-induced psychosis as an example. ( 18779776 )
2008
15
Substance-induced psychosis: a diagnostic conundrum. ( 18278990 )
2008
16
Stability of early-phase primary psychotic disorders with concurrent substance use and substance-induced psychosis. ( 17267925 )
2007
17
Remission one year after emergency admission is higher for substance-induced psychosis than primary psychosis. ( 17459972 )
2007
18
Substance-Induced Psychosis. ( 10085193 )
1998
19
Differential diagnosis of substance-induced psychosis and schizophrenia in patients with substance use disorders. ( 9165629 )
1997
20
Substance-induced psychosis. ( 8829765 )
1996
21
Substance-induced psychosis. ( 8733808 )
1996

Variations for Substance-Induced Psychosis

Expression for Substance-Induced Psychosis

Search GEO for disease gene expression data for Substance-Induced Psychosis.

Pathways for Substance-Induced Psychosis

Pathways related to Substance-Induced Psychosis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.22 HTR1A HTR2A
2 11.01 HTR1A HTR2A
3 10.07 HTR1A HTR2A

GO Terms for Substance-Induced Psychosis

Biological processes related to Substance-Induced Psychosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 behavior GO:0007610 9.26 HTR1A HTR2A
2 regulation of behavior GO:0050795 9.16 HTR1A HTR2A
3 serotonin receptor signaling pathway GO:0007210 8.96 HTR1A HTR2A
4 regulation of hormone secretion GO:0046883 8.62 HTR1A HTR2A

Molecular functions related to Substance-Induced Psychosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transducer activity GO:0004871 9.43 FZD3 HTR1A HTR2A
2 G-protein coupled serotonin receptor activity GO:0004993 9.16 HTR1A HTR2A
3 neurotransmitter receptor activity GO:0030594 8.96 HTR1A HTR2A
4 serotonin binding GO:0051378 8.62 HTR1A HTR2A

Sources for Substance-Induced Psychosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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