MCID: SBS002
MIFTS: 29

Substernal Goiter malady

Category: Endocrine diseases

Aliases & Classifications for Substernal Goiter

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Aliases & Descriptions for Substernal Goiter:

Name: Substernal Goiter 10 12 65
Retrosternal Thyroid Goiter 10
 
Goiter, Substernal 36

Classifications:



External Ids:

Disease Ontology10 DOID:13200
SNOMED-CT59 190234009, 66392007
MeSH36 D006045
UMLS65 C0018024

Summaries for Substernal Goiter

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MalaCards based summary: Substernal Goiter, also known as retrosternal thyroid goiter, is related to goiter and laryngitis. An important gene associated with Substernal Goiter is F7 (Coagulation Factor VII), and among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include thyroid, prostate and endothelial, and related mouse phenotypes are craniofacial and homeostasis/metabolism.

Related Diseases for Substernal Goiter

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Graphical network of the top 20 diseases related to Substernal Goiter:



Diseases related to substernal goiter

Symptoms for Substernal Goiter

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Drugs & Therapeutics for Substernal Goiter

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Substernal Goiter


Cochrane evidence based reviews: goiter, substernal

Genetic Tests for Substernal Goiter

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Anatomical Context for Substernal Goiter

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MalaCards organs/tissues related to Substernal Goiter:

33
Thyroid, Prostate, Endothelial, Breast, Eye, Monocytes, T cells

Animal Models for Substernal Goiter or affiliated genes

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MGI Mouse Phenotypes related to Substernal Goiter:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.0F7, NOTCH1, PTH
2MP:00053767.2CD79A, F7, NOTCH1, PTH, TG

Publications for Substernal Goiter

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Articles related to Substernal Goiter:

(show top 50)    (show all 74)
idTitleAuthorsYear
1
Strategies of laparoscopic thyroidectomy for treatment of substernal goiter via areola approach. (27005286)
2016
2
Sternotomy for substernal goiter: retrospective study of 52 operations. (25691265)
2015
3
Harmonic focus in thyroidectomy for substernal goiter. (25752670)
2015
4
Substernal goiter: Experience with 50A cases. (26520480)
2015
5
Recurrent laryngeal nerve palsy and substernal goiter. An Italian multicenter study. (24880605)
2014
6
Successful management of trachea stenosis with massive substernal goiter via thacheobronchial stent. (24228633)
2013
7
Chylothorax associated with substernal goiter treated with transcervical thyroidectomy. (21476890)
2011
8
Single-stage operation for giant substernal goiter with severe coronary artery disease. (21881378)
2011
9
Morbidity and mortality of thyroidectomy for substernal goiter. (19827121)
2010
10
Image in endocrinology. Pemberton's sign in patient with substernal goiter. (20823469)
2010
11
Management of the substernal goiter: a team approach. (20830956)
2010
12
Incidental detection of internal jugular vein thrombosis secondary to undiagnosed benign substernal goiter. (20814560)
2010
13
A critical analysis of 33 patients with substernal goiter surgically treated by neck incision. (19575100)
2009
14
Evidence-based surgical management of substernal goiter. (18266028)
2008
15
Surgical treatment of substernal goiter: an analysis of 59 patients. (18516529)
2008
16
Extended tracheal stenosis secondary to a massive substernal goiter. (17956165)
2007
17
Thyroidectomy for substernal goiter via a mediastinoscopic approach. (16999061)
2006
18
Substernal goiter: an unusual cause of respiratory failure after coronary artery bypass grafting. (16107122)
2005
19
Predictors of airway complications after thyroidectomy for substernal goiter. (15197094)
2004
20
Novel technique for control of mediastinal bleeding during thyroidectomy for substernal goiter. (12742217)
2003
21
Visual vignette. Mediastinal mass due to substernal goiter. (12134778)
2002
22
Detection of a large substernal goiter during Tc-99m tetrofosmin cardiac SPECT imaging. (11391314)
2001
23
Operative management of substernal goiter: analysis of 52 patients. (12056465)
2001
24
Calcified substernal goiter seen on bone scan. (10983765)
2000
25
Surgical management of substernal goiter. (11155771)
2000
26
Surgical treatment of substernal goiter. (11324994)
2000
27
Bilateral recurrent nerve paralysis associated with multinodular substernal goiter: a case report. (10231217)
1999
28
Substernal goiter: clinical experience of 72 cases. (10335714)
1999
29
Use of a Foley catheter in the removal of a substernal goiter. (9817262)
1998
30
Management of substernal goiter. (9818814)
1998
31
Giant mediastinal parathyroid cyst masquerading as a substernal goiter. (9121802)
1997
32
Substernal goiter. (7475073)
1995
33
Surgical management of substernal goiter: analysis of 237 patients. (7661484)
1995
34
Gastric pull-through imitating substernal goiter. (8062480)
1994
35
Surgical management of substernal goiter. (7863290)
1994
36
A case report of substernal goiter. (8014069)
1993
37
Large parathyroid functioning carcinoma (1,200 g) presenting as a substernal goiter. (1560189)
1992
38
Surgery of substernal goiter. (3331229)
1987
39
Substernal goiter. Analysis of 80 patients from Massachusetts General Hospital. (3970328)
1985
40
Substernal goiter. (3885887)
1985
41
Sequestered substernal goiter. (6625801)
1983
42
Sequestered substernal goiter. (6679211)
1983
43
Esophageal tracer retention simulating substernal goiter. (845672)
1977
44
Substernal goiter with superior vena caval obstruction. (1129707)
1975
45
Airway obstruction in substernal goiter. Clinical and therapeutic implications. (4777540)
1973
46
Substernal goiter. (5428874)
1970
47
INTRATHORACIC AND SUBSTERNAL GOITER: SOME CONSIDERATION IN MANAGEMENT. (14079533)
1963
48
A consideration of the proper surgical approach for substernal goiter. (14408062)
1960
49
Differential diagnosis, pathology, and treatment of substernal goiter. (13398297)
1957
50
A case of substernal goiter with preoperative symptoms of parathyroid tetany. (15399001)
1950

Variations for Substernal Goiter

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Expression for genes affiliated with Substernal Goiter

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Search GEO for disease gene expression data for Substernal Goiter.

Pathways for genes affiliated with Substernal Goiter

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Pathways related to Substernal Goiter according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1CD79A, NOTCH1
29.1CD79A, PTH

GO Terms for genes affiliated with Substernal Goiter

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Biological processes related to Substernal Goiter according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell migrationGO:00303359.5F7, NOTCH1
2regulation of gene expressionGO:00104689.1NOTCH1, PTH

Sources for Substernal Goiter

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet