MCID: SBS002
MIFTS: 23

Substernal Goiter malady

Endocrine diseases category
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Summaries for Substernal Goiter

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MalaCards based summary: Substernal Goiter, also known as retrosternal thyroid goiter, is related to goiter and mediastinitis. An important gene associated with Substernal Goiter is CASK (calcium/calmodulin-dependent serine protein kinase (MAGUK family)). Affiliated tissues include thyroid, bone and trachea.

Aliases & Classifications for Substernal Goiter

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Substernal Goiter, Aliases & Descriptions:

Name: Substernal Goiter 8 10 62
 
Retrosternal Thyroid Goiter 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


External Ids:

Disease Ontology8 DOID:13200
SNOMED-CT57 190234009, 66392007
MeSH34 D006045

Related Diseases for Substernal Goiter

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Diseases related to Substernal Goiter via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1goiter11.1
2mediastinitis10.5
3artery disease10.4
4laryngitis10.4
5thyroiditis10.4
6ischemic optic neuropathy10.2
7pulmonary emphysema10.2
8obstructive sleep apnea10.2
9tracheal stenosis10.2
10aortic aneurysm10.2
11esophagitis10.2
12neuropathy10.2
13respiratory failure10.2
14sleep apnea10.2
15thyrotoxicosis10.2
16superior vena cava syndrome10.2
17aneurysm10.2
18syncope10.2
19solitary fibrous tumor10.2

Graphical network of diseases related to Substernal Goiter:



Diseases related to substernal goiter

Symptoms for Substernal Goiter

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Drugs & Therapeutics for Substernal Goiter

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Drug clinical trials:

Search ClinicalTrials for Substernal Goiter

Search NIH Clinical Center for Substernal Goiter

Genetic Tests for Substernal Goiter

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Anatomical Context for Substernal Goiter

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MalaCards organs/tissues related to Substernal Goiter:

32
Thyroid, Bone, Trachea

Animal Models for Substernal Goiter or affiliated genes

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Publications for Substernal Goiter

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Articles related to Substernal Goiter:

(show top 50)    (show all 65)
idTitleAuthorsYear
1
Recurrent laryngeal nerve palsy and substernal goiter. An Italian multicenter study. (24880605)
2014
2
eComment. Substernal goiter. Beware of the thyroidea ima artery. (24944323)
2014
3
Successful management of trachea stenosis with massive substernal goiter via thacheobronchial stent. (24228633)
2013
4
Chylothorax associated with substernal goiter treated with transcervical thyroidectomy. (21476890)
2011
5
Single-stage operation for giant substernal goiter with severe coronary artery disease. (21881378)
2011
6
Morbidity and mortality of thyroidectomy for substernal goiter. (19827121)
2010
7
Image in endocrinology. Pemberton's sign in patient with substernal goiter. (20823469)
2010
8
Management of the substernal goiter: a team approach. (20830956)
2010
9
Incidental detection of internal jugular vein thrombosis secondary to undiagnosed benign substernal goiter. (20814560)
2010
10
Clinical images. Solitary fibrous tumor of the perithyroidal soft tissue mimicking substernal goiter. (20609717)
2010
11
A critical analysis of 33 patients with substernal goiter surgically treated by neck incision. (19575100)
2009
12
Evidence-based surgical management of substernal goiter. (18266028)
2008
13
Surgical treatment of substernal goiter: an analysis of 59 patients. (18516529)
2008
14
Extended tracheal stenosis secondary to a massive substernal goiter. (17956165)
2007
15
Thyroidectomy for substernal goiter via a mediastinoscopic approach. (16999061)
2006
16
Substernal goiter: an unusual cause of respiratory failure after coronary artery bypass grafting. (16107122)
2005
17
Predictors of airway complications after thyroidectomy for substernal goiter. (15197094)
2004
18
Novel technique for control of mediastinal bleeding during thyroidectomy for substernal goiter. (12742217)
2003
19
Visual vignette. Mediastinal mass due to substernal goiter. (12134778)
2002
20
Detection of a large substernal goiter during Tc-99m tetrofosmin cardiac SPECT imaging. (11391314)
2001
21
Operative management of substernal goiter: analysis of 52 patients. (12056465)
2001
22
Calcified substernal goiter seen on bone scan. (10983765)
2000
23
Surgical management of substernal goiter. (11155771)
2000
24
Surgical treatment of substernal goiter. (11324994)
2000
25
Bilateral recurrent nerve paralysis associated with multinodular substernal goiter: a case report. (10231217)
1999
26
Substernal goiter: clinical experience of 72 cases. (10335714)
1999
27
Use of a Foley catheter in the removal of a substernal goiter. (9817262)
1998
28
Management of substernal goiter. (9818814)
1998
29
Use of a Foley catheter in the removal of a substernal goiter. (9515535)
1998
30
Giant mediastinal parathyroid cyst masquerading as a substernal goiter. (9121802)
1997
31
Substernal goiter. (7475073)
1995
32
Surgical management of substernal goiter: analysis of 237 patients. (7661484)
1995
33
Gastric pull-through imitating substernal goiter. (8062480)
1994
34
Surgical management of substernal goiter. (7863290)
1994
35
A case report of substernal goiter. (8014069)
1993
36
Large parathyroid functioning carcinoma (1,200 g) presenting as a substernal goiter. (1560189)
1992
37
A large substernal goiter as a cause of a pulmonary perfusion defect. (1963388)
1990
38
Substernal goiter versus intrathoracic aberrant thyroid: a critical difference. (3196104)
1988
39
Surgery of substernal goiter. (3331229)
1987
40
Substernal goiter. (3885887)
1985
41
Sequestered substernal goiter. (6625801)
1983
42
Sequestered substernal goiter. (6679211)
1983
43
Esophageal tracer retention simulating substernal goiter. (845672)
1977
44
Substernal goiter with superior vena caval obstruction. (1129707)
1975
45
Airway obstruction in substernal goiter. Clinical and therapeutic implications. (4777540)
1973
46
Substernal goiter. (5428874)
1970
47
INTRATHORACIC AND SUBSTERNAL GOITER: SOME CONSIDERATION IN MANAGEMENT. (14079533)
1963
48
A consideration of the proper surgical approach for substernal goiter. (14408062)
1960
49
Differential diagnosis, pathology, and treatment of substernal goiter. (13398297)
1957
50
A case of substernal goiter with preoperative symptoms of parathyroid tetany. (15399001)
1950

Variations for Substernal Goiter

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Expression for genes affiliated with Substernal Goiter

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Expression patterns in normal tissues for genes affiliated with Substernal Goiter

Search GEO for disease gene expression data for Substernal Goiter.

Pathways for genes affiliated with Substernal Goiter

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Compounds for genes affiliated with Substernal Goiter

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GO Terms for genes affiliated with Substernal Goiter

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Products for genes affiliated with Substernal Goiter

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  • Antibodies
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Sources for Substernal Goiter

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet