MCID: SBS002
MIFTS: 23

Substernal Goiter malady

Endocrine diseases category
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Summaries for Substernal Goiter

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33MalaCards
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MalaCards: Substernal Goiter, also known as retrosternal thyroid goiter, is related to goiter and mediastinitis. An important gene associated with Substernal Goiter is CASK (calcium/calmodulin-dependent serine protein kinase (MAGUK family)). Affiliated tissues include thyroid, bone and testes.

Aliases & Classifications for Substernal Goiter

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


Aliases & Descriptions:

substernal goiter 8 10 62
retrosternal thyroid goiter 8


External Ids:

Disease Ontology8 DOID:13200
SNOMED-CT58 190234009, 66392007
MeSH35 D006045

Related Diseases for Substernal Goiter

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17GeneCards, 18GeneDecks
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Diseases related to Substernal Goiter via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1goiter11.1
2mediastinitis10.4
3coronary artery disease10.4
4artery disease10.4
5thyroiditis10.4
6obstructive sleep apnea10.2
7tracheal stenosis10.2
8aortic aneurysm10.2
9esophagitis10.2
10laryngitis10.2
11neuropathy10.2
12pulmonary emphysema10.2
13respiratory failure10.2
14sleep apnea10.2
15thyrotoxicosis10.2
16superior vena cava syndrome10.2
17aneurysm10.2
18syncope10.2
19solitary fibrous tumor10.2

Graphical network of diseases related to Substernal Goiter:



Diseases related to substernal goiter

Symptoms for Substernal Goiter

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Drugs & Therapeutics for Substernal Goiter

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Substernal Goiter

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Anatomical Context for Substernal Goiter

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33MalaCards
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MalaCards organs/tissues related to Substernal Goiter:

33
Thyroid, Bone, Testes, Trachea

Animal Models for Substernal Goiter or affiliated genes

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Publications for Substernal Goiter

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52PubMed
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Articles related to Substernal Goiter:

(show top 50)    (show all 63)
idTitleAuthorsYear
1
Successful management of trachea stenosis with massive substernal goiter via thacheobronchial stent. (24228633)
2013
2
Chylothorax associated with substernal goiter treated with transcervical thyroidectomy. (21476890)
2011
3
Single-stage operation for giant substernal goiter with severe coronary artery disease. (21881378)
2011
4
Morbidity and mortality of thyroidectomy for substernal goiter. (19827121)
2010
5
Management of the substernal goiter: a team approach. (20830956)
2010
6
Incidental detection of internal jugular vein thrombosis secondary to undiagnosed benign substernal goiter. (20814560)
2010
7
Clinical images. Solitary fibrous tumor of the perithyroidal soft tissue mimicking substernal goiter. (20609717)
2010
8
Substernal goiter: what is in a definition? (20109623)
2010
9
A critical analysis of 33 patients with substernal goiter surgically treated by neck incision. (19575100)
2009
10
Evidence-based surgical management of substernal goiter. (18266028)
2008
11
Surgical treatment of substernal goiter: an analysis of 59 patients. (18516529)
2008
12
Extended tracheal stenosis secondary to a massive substernal goiter. (17956165)
2007
13
Thyroidectomy for substernal goiter via a mediastinoscopic approach. (16999061)
2006
14
Substernal goiter: an unusual cause of respiratory failure after coronary artery bypass grafting. (16107122)
2005
15
Predictors of airway complications after thyroidectomy for substernal goiter. (15197094)
2004
16
Novel technique for control of mediastinal bleeding during thyroidectomy for substernal goiter. (12742217)
2003
17
Visual vignette. Mediastinal mass due to substernal goiter. (12134778)
2002
18
Detection of a large substernal goiter during Tc-99m tetrofosmin cardiac SPECT imaging. (11391314)
2001
19
Operative management of substernal goiter: analysis of 52 patients. (12056465)
2001
20
Calcified substernal goiter seen on bone scan. (10983765)
2000
21
Surgical management of substernal goiter. (11155771)
2000
22
Surgical treatment of substernal goiter. (11324994)
2000
23
Bilateral recurrent nerve paralysis associated with multinodular substernal goiter: a case report. (10231217)
1999
24
Substernal goiter: clinical experience of 72 cases. (10335714)
1999
25
Use of a Foley catheter in the removal of a substernal goiter. (9817262)
1998
26
Management of substernal goiter. (9818814)
1998
27
Use of a Foley catheter in the removal of a substernal goiter. (9515535)
1998
28
Giant mediastinal parathyroid cyst masquerading as a substernal goiter. (9121802)
1997
29
Substernal goiter. (7475073)
1995
30
Surgical management of substernal goiter: analysis of 237 patients. (7661484)
1995
31
Gastric pull-through imitating substernal goiter. (8062480)
1994
32
Surgical management of substernal goiter. (7863290)
1994
33
A case report of substernal goiter. (8014069)
1993
34
Large parathyroid functioning carcinoma (1,200 g) presenting as a substernal goiter. (1560189)
1992
35
A large substernal goiter as a cause of a pulmonary perfusion defect. (1963388)
1990
36
Substernal goiter versus intrathoracic aberrant thyroid: a critical difference. (3196104)
1988
37
Surgery of substernal goiter. (3331229)
1987
38
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1987. A 56-year-old man with a substernal goiter, multiple cutaneous and mucosal lesions, and a positive stool test for occult blood. (3587282)
1987
39
Substernal goiter. Analysis of 80 patients from Massachusetts General Hospital. (3970328)
1985
40
Substernal goiter. (3885887)
1985
41
Sequestered substernal goiter. (6625801)
1983
42
Sequestered substernal goiter. (6679211)
1983
43
Esophageal tracer retention simulating substernal goiter. (845672)
1977
44
Substernal goiter with superior vena caval obstruction. (1129707)
1975
45
Airway obstruction in substernal goiter. Clinical and therapeutic implications. (4777540)
1973
46
Substernal goiter. (5428874)
1970
47
INTRATHORACIC AND SUBSTERNAL GOITER: SOME CONSIDERATION IN MANAGEMENT. (14079533)
1963
48
A consideration of the proper surgical approach for substernal goiter. (14408062)
1960
49
Differential diagnosis, pathology, and treatment of substernal goiter. (13398297)
1957
50
A case of substernal goiter with preoperative symptoms of parathyroid tetany. (15399001)
1950

Variations for Substernal Goiter

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Expression for genes affiliated with Substernal Goiter

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Substernal Goiter

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Pathways for genes affiliated with Substernal Goiter

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Compounds for genes affiliated with Substernal Goiter

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GO Terms for genes affiliated with Substernal Goiter

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Products for genes affiliated with Substernal Goiter

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  • Antibodies
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Sources for Substernal Goiter

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet