Succinyl-coa:3-ketoacid Coa Transferase Deficiency malady

Genetics Home Reference: Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency is an inherited disorder that impairs the body's ability to break down ketones, which are molecules produced in the liver during the breakdown of fats.¹⁷

MalaCards: Succinyl-coa:3-ketoacid Coa Transferase Deficiency, also known as succinyl-coa:3-oxoacid coa transferase deficiency, is related to diabetic ketoacidosis and ketoacidosis due to scot deficiency. An important gene associated with Succinyl-coa:3-ketoacid Coa Transferase Deficiency is OXCT1 (3-oxoacid CoA transferase 1). Affiliated tissues include liver.

succinyl-coa:3-ketoacid coa transferase deficiency 17 succinyl-coa:3-oxoacid coa transferase deficiency 17 succinyl-coa:acetoacetate transferase deficiency 17 succinyl-coa 3-oxoacid transferase deficiency 17 3-oxoacid coa transferase deficiency 17

ketoacidosis due to scot deficiency 17 deficiency of transferase 43 scot deficiency 17 succinyl-coa 43 ketoacidosis 43

Diseases related to succinyl-coa:3-ketoacid coa transferase deficiency by text searches and GeneDecks gene sharing:

(show all 46)

id	Related Disease	Score	Top Affiliating Genes
1	diabetic ketoacidosis	11.1
2	ketoacidosis due to scot deficiency	9.2
3	scot deficiency	8.3
4	diabetes mellitus	8.1
5	acromegaly	7.1
6	insulin resistance	6.8
7	anemia	6.8
8	encephalomyopathy	6.8
9	pancreatitis	6.8
10	sideroblastic anemia	6.8
11	gastric cancer	6.5
12	propionic acidemia	6.5
13	lactic acidosis	5.9
14	type 1 diabetes mellitus	5.9
15	brain edema	5.9
16	cerebritis	5.9
17	hyperglycemia	5.0
18	somatostatinoma	5.0
19	leukemoid reaction	5.0
20	sepsis	5.0
21	acanthosis nigricans	5.0
22	multiple carboxylase deficiency	5.0
23	seizures	5.0
24	alopecia	5.0
25	maturity-onset diabetes of the young	5.0
26	thyroiditis	5.0
27	maturity-onset diabetes of the young, type 3	5.0
28	type 2 diabetes mellitus	5.0
29	connective tissue disease	5.0
30	mixed connective tissue disease	5.0
31	cerebral infarction	5.0
32	myopathy	5.0
33	duodenal somatostatinoma	5.0
34	neonatal diabetes mellitus	5.0
35	duodenitis	5.0
36	nephrotic syndrome	5.0
37	down syndrome	5.0
38	gigantism	5.0
39	obesity	5.0
40	glucagonoma	5.0
41	pheochromocytoma	5.0
42	gestational diabetes	5.0
43	permanent neonatal diabetes mellitus	5.0
44	hepatitis c	5.0
45	rheumatic fever	5.0
46	hypoglycemia	5.0

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to succinyl-coa:3-ketoacid coa transferase deficiency:

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Genes related to succinyl-coa:3-ketoacid coa transferase deficiency according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	OXCT1	3-oxoacid CoA transferase 1	11.1	Disorders