MCID: SDD001
MIFTS: 60

Sudden Infant Death Syndrome malady

Categories: Genetic diseases, Rare diseases

Aliases & Classifications for Sudden Infant Death Syndrome

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Aliases & Descriptions for Sudden Infant Death Syndrome:

Name: Sudden Infant Death Syndrome 50 11 46 13 68 25 48 36 2 66
Sids 11 46 68 2
Sudden Infant Death Syndrome, Susceptibility to 12
Sudden Death of Nonspecific Cause in Infancy 11
 
Sudden Infant Death Syndrome Nos 11
Sudden Infant Death 37
Crib Death 11
Cot Death 11

Characteristics:

HPO:

62
sudden infant death syndrome:
Mortality/Aging: sudden death


Classifications:



External Ids:

OMIM50 272120
Disease Ontology11 DOID:9007
ICD9CM30 798.0
MeSH37 D013398
NCIt43 C85173
MedGen35 C0038644
ICD1028 R95

Summaries for Sudden Infant Death Syndrome

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MedlinePlus:36 Sudden infant death syndrome (sids) is the sudden, unexplained death of an infant younger than one year old. some people call sids "crib death" because many babies who die of sids are found in their cribs. sids is the leading cause of death in children between one month and one year old. most sids deaths occur when babies are between two months and four months old. premature babies, boys, african americans, and american indian/alaska native infants have a higher risk of sids. although health care professionals don't know what causes sids, they do know ways to reduce the risk. these include placing babies on their backs to sleep, even for short naps. "tummy time" is for when babies are awake and someone is watching using a firm sleep surface, such as a crib mattress covered with a fitted sheet keeping soft objects and loose bedding away from sleep area making sure babies don't get too hot. keep the room at a comfortable temperature for an adult. don't smoke during pregnancy or allow anyone to smoke near your baby nih: national institute of child health and human development

MalaCards based summary: Sudden Infant Death Syndrome, also known as sids, is related to sudden infant death with dysgenesis of the testes syndrome and cav3-related sudden infant death syndrome, and has symptoms including disturbance of thermoregulation of newborn, disturbance of thermoregulation of newborn and apneic episodes in infancy. An important gene associated with Sudden Infant Death Syndrome is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways are Phase 1 - inactivation of fast Na+ channels and Antiarrhythmic Pathway, Pharmacodynamics. Affiliated tissues include brain, skin and heart, and related mouse phenotypes are muscle and cardiovascular system.

Disease Ontology:11 A syndrome that is characterized by the sudden death of an infant that is not predicted by medical history and remains unexplained after a thorough forensic autopsy and detailed death scene investigation.

NIH Rare Diseases:46 Sudden infant death syndrome (sids) is the unexpected, sudden death of a child under age 1 which cannot be explained after a thorough investigation is conducted. infants who are affected by the condition generally appear healthy with no suspicious signs and symptoms prior to the incident. it is the leading cause of death in infants age 1 to 12 months old. the exact underlying cause of sids is unknown; however, scientists suspect that it is likely a multifactorial condition (associated with the effects of multiple genes in combination with lifestyle and environmental factors). although there is no guaranteed way to prevent sids, the american academy of pediatrics has a published list of recommendations for risk reduction. please click on the link to access this resource. last updated: 12/15/2015

UniProtKB/Swiss-Prot:68 Sudden infant death syndrome: SIDS is the sudden death of an infant younger than 1 year that remains unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of clinical history. Pathophysiologic mechanisms for SIDS may include respiratory dysfunction, cardiac dysrhythmias, cardiorespiratory instability, and inborn errors of metabolism, but definitive pathogenic mechanisms precipitating an infant sudden death remain elusive.

OMIM:50 Sudden infant death syndrome (SIDS) is a diagnosis of exclusion which should be made only after a thorough autopsy... (272120) more...

Wikipedia:69 Sudden infant death syndrome (SIDS), also known as cot death or crib death, is the sudden unexplained... more...

Related Diseases for Sudden Infant Death Syndrome

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Diseases in the Sudden Infant Death Syndrome family:

Cav3-Related Sudden Infant Death Syndrome

Diseases related to Sudden Infant Death Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 90)
idRelated DiseaseScoreTop Affiliating Genes
1sudden infant death with dysgenesis of the testes syndrome12.8
2cav3-related sudden infant death syndrome12.3
3mucopolysaccharidosis ii10.9
4submucous uterine fibroid10.9GPD1L, SCN2B, SCN5A
5brugada syndrome 210.9GPD1L, SCN5A
6todd's paralysis10.9KCNH2, KCNQ1, SCN5A
7microcephaly-polymicrogyria-corpus callosum agenesis syndrome10.9KCNH2, KCNQ1, SCN5A
8cone dystrophy10.8KCNH2, KCNQ1, SCN5A
9second-degree atrioventricular block10.8KCNH2, KCNQ1, SCN5A
10prostate malignant phyllodes tumor10.8KCNH2, KCNQ1, SCN5A
11dissociative disorder10.8IDS, SLC6A4
12atrial fibrillation, familial, 310.8CAV3, KCNH2, KCNQ1, SCN5A
13acute tricyclic antidepressant poisoning10.8KCNH2, KCNQ1
14sult4a1-related altered drug metabolism10.8KCNH2, KCNQ1, SCN5A, SNTA1
15vitelliform macular dystrophy10.8KCNH2, KCNQ1, SCN2B, SCN5A
16lymphoplasmacytic lymphoma10.8KCNH2, KCNQ1, SCN5A
17jervell and lange-nielsen syndrome10.7CAV3, KCNH2, KCNQ1, SCN5A, SNTA1
18melancholia10.7CAV3, KCNH2, KCNQ1, SCN5A, SNTA1
19periventricular nodular heterotopia10.6CAV3, GPD1L, KCNH2, KCNJ8, KCNQ1, SCN2B
20hyperekplexia10.6
21adams-oliver syndrome10.6KCNQ1, SCN2B, SCN5A
22cardiac conduction disease with or without dilated cardiomyopathy10.5KCNH2, KCNQ1
23reye syndrome10.5
24infantile apnea10.5
25chicken egg allergy10.4MT-ND1, SCN5A, SNTA1
26neuronitis10.3
27hypoxia10.3
28long qt syndrome10.3
29parkinson disease, late-onset10.3ADCYAP1, MT-ND1, SLC6A4, TH
30ventricular fibrillation, familial, 110.2HBN1, SCN5A
31sick sinus syndrome 110.2HBN1, SCN5A
32atrial fibrillation, familial, 1010.2HBN1, SCN5A
33brugada syndrome 110.2HBN1, KCNH2, SCN5A
34laryngitis10.1
35infantile histiocytoid cardiomyopathy10.1
36long qt syndrome-310.1HBN1, SCN5A
37heart block, progressive, type ia10.1HBN1, SCN5A
38infant botulism10.1
39botulism10.1
40cerebritis10.0
41hypophosphatemia9.9
42toxic shock syndrome9.9
43pneumonia9.9
44myocarditis9.9
45asthma9.8
46orthostatic intolerance9.8
47ectodermal dysplasia9.8
48hepatitis9.8
49desquamative interstitial pneumonia9.8
50brugada syndrome9.8

Graphical network of the top 20 diseases related to Sudden Infant Death Syndrome:



Diseases related to sudden infant death syndrome

Symptoms for Sudden Infant Death Syndrome

About this section

Symptoms by clinical synopsis from OMIM:

272120

Clinical features from OMIM:

272120

HPO human phenotypes related to Sudden Infant Death Syndrome:

id Description Frequency HPO Source Accession
1 apneic episodes in infancy HP:0005949

UMLS symptoms related to Sudden Infant Death Syndrome:


disturbance of thermoregulation of newborn

Drugs & Therapeutics for Sudden Infant Death Syndrome

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Drugs for Sudden Infant Death Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
NicotinePhase 4, Phase 2101654-11-5942, 89594
Synonyms:
(−
(+)-Nicotine
(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(+-)-Nicotine
(-)-3-(1-Methyl-2-pyrrolidyl)pyridine
(-)-3-(N-Methylpyrrolidino)pyridine
(-)-Nicotine
(-)-Nicotine solution
(2S) 3-(1-Methyl-pyrrolidin-2-yl)-pyridine
(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(R,S)-Nicotine
(R,S)-nicotine
(RS)-nicotine
(S)-(-)-NICOTINE, 3-[(2S)-1-METHYL-2-PYRROLIDINYL] PYRIDINE
(S)-(-)-Nicotine
(S)-3-(1-methylpyrrolidin-2-yl)pyridine
(S)-3-(N-methylpyrrolidin-2-yl)pyridine
(S)-Nicotine
(±)-nicotine
)-1-Methyl-2-(3-pyridyl)pyrrolidine
)-Nicotine
)-Nicotine solution
1-Methyl-2-(3-pyridal)-Pyrrolidine
1-Methyl-2-(3-pyridal)-pyrrolidene
1-Methyl-2-(3-pyridiyl)pyrrolidine
1-Methyl-2-(3-pyridyl)pyrrolidine
1uw6
2'-beta-H-Nicotine
3-(1-Methyl-2-pyrollidinyl)pyridine
3-(1-Methyl-2-pyrrolidinyl)-Pyridine
3-(1-Methyl-2-pyrrolidinyl)pyridine
3-(1-Methylpyrrolidin-2-yl)pyridine
3-(2-(N-methylpyrrolidinyl))pyridine
3-(N-Methylpyrollidino)pyridine
3-(N-Methylpyrrolidino)pyridine
3-N-Methylpyrrolidine
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
36733_FLUKA
36733_RIEDEL
434F7990-3240-4A43-ACEC-E6CC1E495FA0
46343_FLUKA
46343_RIEDEL
54-11-5
AC1L3I79
AC1Q3ZOC
AI3-03424
BB_NC-0777
BIDD:GT0599
BRD-K05395900-322-02-1
Black Leaf
Black Leaf 40
C00745
CCRIS 1637
CHEBI:17688
CHEMBL3
CID89594
CPD000059074
Campbell's Nico-Soap
Caswell No. 597
Commit
D-Nicotine
D03365
DL-tetrahydronicotyrine
Destruxol
Destruxol Orchid Spray
EINECS 200-193-3
ENT 3,424
EPA Pesticide Chemical Code 056702
Emo-Nik
Flux Maag
Fumeto bac
Fumetobac
HSDB 1107
Habitrol
Habitrol (TN)
L(-)-nicotine
L-3-(1-Methyl-2-pyrrolidyl)pyridine
 
L-Nicotine
LS-202
MLS001055457
MLS001335905
Mach-Nic
Methyl-2-pyrrolidinyl)pyridine
Micotine
MolPort-000-744-731
N3876_SIGMA
N5511_FLUKA
N5511_SIGMA
NCGC00090693-01
NCGC00090693-02
NCGC00090693-03
NCGC00090693-04
NCGC00090693-05
NCGC00090693-06
NCGC00090693-07
NCT
NICOTINE AND SALTS
NSC 5065
NSC97238
Niagara P.A. Dust
Nic-Sal
Nico-Dust
Nico-Fume
Nicocide
Nicoderm
Nicoderm Cq
Nicoderm Patch
Nicorette
Nicorette Plus
Nicotin
Nicotina
Nicotina [Italian]
Nicotine
Nicotine (USP)
Nicotine (compounds related to)
Nicotine Alkaloid
Nicotine Patch
Nicotine Polacrilex
Nicotine [BSI:ISO]
Nicotine [UN1654]
Nicotine [UN1654] [Poison]
Nicotine [USAN]
Nicotrol
Nicotrol Inhaler
Nicotrol Ns
Nictoine patch
Nikotin
Nikotin [German]
Nikotyna
Nikotyna [Polish]
Ortho N-4 Dust
Ortho N-5 Dust
PDSP1_000113
PDSP1_000465
PDSP2_000463
PDSP2_000555
Prostep
R)-(+)-Nicotine
RCRA waste no. P075
RCRA waste number P075
SAM002564224
SDCCGMLS-0066911.P001
SMR000059074
Tendust
Transdermal Nicotine
UN1654
a -N-Methylpyrrolidine
a-N-Methylpyrrolidine
alpha-N-Methylpyrrolidine
beta-Pyridyl-alpha-N-methyl pyrrolidine
beta-Pyridyl-alpha-N-methylpyrrolidine
bmse000105
delta-Nicotine
nicotine
nicotine replacement patch
2
LabetalolPhase 2, Phase 3, Phase 13136894-69-63869
Synonyms:
2-Hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)benzamide
2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide
2-hydroxy-5-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl}benzamide
3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol
36894-69-6
5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide
AB00053659
AC-18747
AC1L1GW8
AH 5158
AH-5158
Albetol
BPBio1_000170
BRD-A07440155-003-05-6
BSPBio_000154
BSPBio_003142
C07063
CHEBI:6343
CHEMBL429
CID3869
D08106
DB00598
DivK1c_000474
EINECS 253-258-3
HSDB 6537
IDI1_000474
Ibidomide
KBio1_000474
KBio2_002087
KBio2_004655
KBio2_007223
 
KBio3_002642
KBioGR_000727
KBioSS_002087
L001344
LS-26936
Labetalol
Labetalol (INN)
Labetalol [INN:BAN]
Labetalolum
Labetalolum [INN-Latin]
Labetolol
Lopac0_000687
MolPort-003-898-140
NCGC00015595-06
NCGC00089800-02
NINDS_000474
NORMOZIDE
Prestwick0_000277
Prestwick1_000277
Prestwick2_000277
Prestwick3_000277
SBB067266
SPBio_000905
SPBio_002373
Sch-19927
Spectrum2_000863
Spectrum3_001581
Spectrum4_000184
Spectrum5_001010
Spectrum_001607
TL8002725
UNII-R5H8897N95
labetalol
3calcium channel blockersPhase 2, Phase 3, Phase 11889
4
Magnesium SulfatePhase 2, Phase 31597487-88-924083
Synonyms:
(C10-C16) Alkylalcohol sulfuric acid, magnesium salt
00627_FLUKA
10028-26-9
10034-99-8 (heptahydrate)
13143_RIEDEL
13143_SIAL
139939-75-6
18939-43-0
203726_ALDRICH
208094_SIAL
34276_FLUKA
34276_RIEDEL
38146_FLUKA
38146_RIEDEL
63126_FLUKA
63136_FLUKA
63136_SIAL
63139_FLUKA
63139_SIAL
68081-97-0
7487-88-9
AC1L2N76
AC1LAX36
AC1Q1U66
AI3-02029
Bitter salt
C10-C16 Alkyl alcohol sulfuric acid magnesium salt
CCRIS 8411
CHEBI:32599
CID24083
CPD0-2390
Caswell No. 534
D008278
DB00653
EINECS 231-298-2
EINECS 233-073-4
EINECS 242-691-3
EINECS 268-365-0
EPA Pesticide Chemical Code 050503
Epsom salt
HSDB 664
Hair salt
Heptahydrate Magnesium Sulfate
Kieserite [as monohydrate]
LS-88605
M2643_SIGMA
M3409_SIGMA
 
M7506_SIAL
M8150_SIGMA
MAGNESIUM SULFATE
Magnesium Sulfate In Plastic Container
Magnesium Sulfate, Heptahydrate
Magnesium Sulphate Hydrate
Magnesium bisulfate
Magnesium hydrogensulphate
Magnesium sulfate
Magnesium sulfate (1:1)
Magnesium sulfate anhydrous
Magnesium sulfate dried
Magnesium sulfate heptahydrate
Magnesium sulfate hexahydrate
Magnesium sulfate in dextrose 5% in plastic container
Magnesium sulfate solution
Magnesium sulphate
Magnesium sulphate anhydrous
Magnesium sulphate dried
Magnesium sulphate heptahydrate
Magnesium(II) sulfate
Magnesium(ii) sulfate
Magnesiumsulfat
MgSO4
MolPort-003-925-000
NSC 146179
OT-S
OT-S (drying agent)
SDA 15-062-07
Sal Angalis
Sal De sedlitz
Sal amarum
Sal anglicum
Sal catharticum
Sal seidlitense
Salts of england
Sel d'angleterre
Sulfate, Magnesium
Sulfuric acid magnesium salt
Sulfuric acid magnesium salt (1:1)
Sulfuric acid magnesium salt (VAN)
Sulfuric acid, C10-16 alkyl ester, magnesium salt
Sulfuric acid, magnesium salt
Sulfuric acid, magnesium salt (1:1)
Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts
Tomix OT
UNII-DE08037SAB
UNII-ML30MJ2U7I
magnesium(2+) ion sulfate
5
NifedipinePhase 1, Phase 210921829-25-44485
Synonyms:
101539-70-2
101554-38-5
21829-25-4
4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester
5-22-04-00268 (Beilstein Handbook Reference)
60299-11-8 (mono-hydrochloride)
AC-11618
AC1L1I9V
AC1Q4254
AKOS002942507
ARONIS24171
AWD Pharma Brand of Nifedipine
Adalat
Adalat (TN)
Adalat 10
Adalat 20
Adalat 5
Adalat CC
Adalat CR
Adalat Crono
Adalat FT
Adalat Ft
Adalat GITS
Adalat GITS 30
Adalat Gits
Adalat Gits 30
Adalat LA
Adalat LP
Adalat Oros
Adalat PA
Adalat Retard
Adalat XL
Adalate
Adalate LP
Adapine
Adapress
Adcock Ingram Brand of Nifedipine
Adipine XL
Afeditab
Afeditab CR
Afeditab CR (TN)
Alat
Aldipin
Alfadal
Alonix
Alonix S
Alpha-Nifedipine Retard
Angipec
Anifed
Anpine
Apo-Nifed
Aprical
Aprical long
BAY 1040
BAY A 1040
BAY-a 1040
BAYa1040
BCBcMAP01_000046
BIDD:GT0442
BIDD:PXR0034
BIM-0050796.0001
BPBio1_000271
BRN 0497773
BSPBio_000245
BSPBio_001391
BSPBio_002071
Bay-1040
Bay-a-1040
Bay1040
Bayer Brand of Nifedipine
Bio-0733
Bio1_000112
Bio1_000601
Bio1_001090
Bio2_000111
Bio2_000591
Bonacid
C07266
C17H18N2O6
CAS-21829-25-4
CBiol_001826
CCRIS 6074
CHEBI:7565
CHEMBL193
CID4485
CPD000058291
Calcibloc
Calcigard
Calcilat
Camont
Cardifen
Cardilat
Cardionorm
Chronadalate
Chronadalate LP
Chronadalate Lp
Citilat
Coracten
Coracten XL
Coral
Cordafen
Cordaflex
Cordalat
Cordicant
Cordilan
Cordipin
Cordipine
Corinfar
Corotrend
Corynphar
D00437
D009543
DB01115
Depin
Dignokonstant
Dilafed
Dilcor
Dipinkor
DivK1c_000313
Duranifin
EINECS 244-598-3
EU-0100819
Ecodipi
Ecodipin
Ecodipin E
Emaberin
Fedcor
Fedcor Retard
Fenamon
Fenamon SR
Fenamon Sr
Fenigidin
Fenihidin
Fenihidine
Fortipine LA
Glopir
HMS1361F13
HMS1568M07
HMS1791F13
HMS1920P19
HMS1989F13
HMS2051O03
HMS2089H11
HMS2091H20
 
HMS500P15
Hadipin
Hexadilat
I06-0051
I06-1286
IDI1_000313
IDI1_033861
Infedipin
Introcar
KB-1712P
KBio1_000313
KBio2_000111
KBio2_001459
KBio2_002400
KBio2_002679
KBio2_004027
KBio2_004968
KBio2_005247
KBio2_006595
KBio2_007536
KBio3_000221
KBio3_000222
KBio3_001571
KBio3_002879
KBioGR_000111
KBioGR_000627
KBioGR_002400
KBioSS_000111
KBioSS_001459
KBioSS_002405
KRKA Brand of Nifedipine
Kordafen
Korinfar
L001054
LS-1012
Lopac-N-7634
Lopac0_000819
MLS000028521
MLS000758222
MLS001148146
MLS001401371
Macorel
Megalat
MolPort-000-787-707
MolPort-006-822-492
Monohydrochloride, Nifedipine
Myogard
N 7634
N0528
N1fedilat
N7634_SIGMA
NCGC00015748-01
NCGC00015748-02
NCGC00015748-03
NCGC00015748-06
NCGC00015748-13
NCGC00024983-01
NCGC00024983-02
NCGC00024983-03
NCGC00024983-04
NCGC00024983-05
NCGC00024983-06
NCGC00024983-07
NCGC00024983-08
NCGC00091707-01
NINDS_000313
Nedipin
Nicardia
Nifangin
Nifar
Nifdemin
Nifebene
Nifecard
Nifecor
Nifedepat
Nifediac
Nifedical
Nifedical XL
Nifedicor
Nifedin
Nifedine
Nifedipine
Nifedipine (JP15/USP/INN)
Nifedipine Bayer Brand
Nifedipine GTIS
Nifedipine KRKA Brand
Nifedipine Monohydrochloride
Nifedipine Orion Brand
Nifedipine Pfizer Brand
Nifedipine Retard
Nifedipine [USAN:BAN:INN:JAN]
Nifedipine-GTIS
Nifedipino
Nifedipino [INN-Spanish]
Nifedipinum
Nifedipinum [INN-Latin]
Nifedipres
Nifedirex LP
Nifelan
Nifelat
Nifelat Q
Nifelate
Nifensar XL
Nificard
Nifidine
Nifipen
Niphedipine
Oprea1_788617
Orion Brand of Nifedipine
Orix
Oxcord
Pfizer Brand of Nifedipine
Pidilat
Prestwick0_000063
Prestwick1_000063
Prestwick2_000063
Prestwick3_000063
Prestwick_357
Procardia
Procardia (TN)
Procardia XL
S1808_Selleck
SAM001246963
SMR000058291
SPBio_001016
SPBio_002166
SPECTRUM1500431
STK735567
Sepamit
Slofedipine XL
Spectrum2_001058
Spectrum3_000516
Spectrum4_000074
Spectrum5_001278
Spectrum_000979
Tensipine MR
Tibricol
Tocris-1075
UNII-I9ZF7L6G2L
Vascard
ZINC19594578
Zenusin
cMAP_000042
nchembio.95-comp13
nifedipine
6
clonidinePhase 1, Phase 22194205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10
7
MethyldopaPhase 1, Phase 214555-30-638853
Synonyms:
(-)-3-(3,4-Dihydroxyphenyl)-2-Methyl-L-Alanine Sesqui-Hydrate
(-)-a-methyldopa
(-)-alpha-methyldopa
(-)-methyldopa
(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
(S)-(-)-a-methyldopa
(S)-(-)-alpha-Methyldopa
(S)-(-)-alpha-methyldopa
133161-54-3
1339-75-9
2-Methyl-3-(3,4-dihydroxyphenyl)alanine
3,4-Dihydroxy-2-methylphenylalanine (ACD/Name 4.0)
3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE
3-Hydroxy-.alpha.-methyl-L-tyrosine
3-Hydroxy-alpha-methyl-L-tyrosine
4290-08-8
555-30-6
779-08-8
AC-11671
AC1L20K1
AC1Q29EL
AC1Q29EM
AMD
Aldoclor-150
Aldoclor-250
Aldomet
Aldomet (TN)
Aldometil
Aldomin
Aldoril 15
Aldoril 25
Aldoril D30
Aldoril D50
Aldoril, Dopamet, Dopegyt, Methyldopa
Alpha medopa
Alphamethyldopa
Anhydrous methyldopa
Apo Methyldopa Tab 125mg
Apo Methyldopa Tab 250mg
Apo Methyldopa Tab 500mg
Apo-Methyldopa
Apo-methyldopa
BIDD:GT0620
BPBio1_000365
BSPBio_000331
BSPBio_002021
Bayer 1440 L
Baypresol
Becanta
C07194
CCRIS 4671
CHEBI:61058
CHEMBL459
CID38853
D08205
DB00968
DivK1c_000142
Dopamet
Dopamethyperpax
Dopatec
Dopegit
Dopegyt
Dopergit
EINECS 209-089-2
EU-0100853
Grospisk
HMS1569A13
HMS1920N09
HMS2090B11
HMS2091F04
HMS500H04
HSDB 218
Hyperpax
Hypolag
IDI1_000142
KBio1_000142
KBio2_001417
KBio2_003985
KBio2_006553
KBio3_001521
KBioGR_000547
KBioSS_001417
L(-)-a-Methylalanine
L(-)-alpha-Methylalanine
L(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine
L-(-)-3-(3,4-Dihydroxyphenyl)-2-methyl-Alanine
L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine
L-(-)-a-Methyl-a-methyl-Aldomin
L-(-)-alpha-Methyl-alpha-methyl-Aldomin
L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine
L-(a-MD)
L-(alpha-Md)
L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid
L-Methyl Dopa
L-Methyl dopa
 
L-Methyldopa
L-a-Methyl-(3, 4-dihydroxyphenyl)alanine
L-a-Methyldopa
L-alpha-Methyl DOPA
L-alpha-Methyl-(3, 4-dihydroxyphenyl)alanine
L-alpha-Methyl-3,4-dihydroxyphenylalanine
L-alpha-Methyldopa
LS-216
LT00847269
Lopac0_000853
METHYL DOPA (SEE ALSO METHYL DOPA SESQUIHYDRATE)
MK 351
MK-351
MLS000028644
Medomet
Medopa
Medopal
Medopren
Methoplain
Methyl dopa
Methyl-L-dopa
Methyldopa
Methyldopa (INN)
Methyldopa (L,-)
Methyldopa (anhydrous)
Methyldopa 125 Tab 125mg
Methyldopa 250 Tab
Methyldopa 500 Tab 500mg
Methyldopa anhydrous
Methyldopate
Methyldopate HCL
Methyldopum
Methyldopum [INN-Latin]
Metildopa
Metildopa [INN-Spanish]
Mk. b51
MolPort-001-792-485
NCGC00024667-01
NCGC00024667-02
NCGC00024667-03
NCGC00024667-05
NCGC00024667-06
NCGC00024667-08
NCI-C55721
NINDS_000142
NSC 169916
NSC169916
Novo-Medopa Tab 125mg
Novo-Medopa Tab 250mg
Novo-Medopa Tab 500mg
Novomedopa
Nr.C 2294
Nu-Medopa
Nu-Medopa Tab 125mg
Nu-Medopa Tab 250mg
Nu-Medopa Tab 500mg
Nu-medopa
Presinol
Presolisin
Prestwick0_000326
Prestwick1_000326
Prestwick2_000326
Prestwick3_000326
Prestwick_732
S1642_Selleck
SMR000059170
SPBio_001056
SPBio_002252
SPECTRUM1500403
Sedometil
Sembrina
Spectrum2_001068
Spectrum3_000501
Spectrum4_000054
Spectrum5_001295
Spectrum_000937
Tocris-0584
UNII-56LH93261Y
a-Methyl dopa
a-Methyl-L-3,4-dihydroxyphenylalanine
a-Methyl-L-dopa
a-Methyldopa (van)
alpha Medopa
alpha-Methyl dopa
alpha-Methyl-L-3,4-dihydroxyphenylalanine
alpha-Methyl-L-dopa
alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine
alpha-Methyldihydroxyphenylalanine
alpha-Methyldopa
alpha-Methyldopa (VAN)
alpha-Methyldopa (van)
alpha-methyl-L-dopa
l-3-(3,4-Dihydroxyphenyl)-2-methylalanine
l-alpha-Methyldopa
levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine
α-Methyl dopa
α-methyl-L-dopa
8
Varenicline263249296-44-45310966
Synonyms:
249296-44-4
7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine
7,8,9,10-tetrahydro-6h-6,10-methanoazepino[4,5-g]quinoxaline
AC1L55H0
AC1Q4W6H
AKOS005145561
AR-1H2911
CHEBI:430452
CHEMBL1396
CID170361
CP 526555
 
CP-526,555
Champix
Chantix
D08669
HSDB 7591
I14-1963
LS-187375
UNII-W6HS99O8ZO
Varenicline
Varenicline (INN)
Varenicline tartrate
varenicline
9
Serotonin351050-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine

Interventional clinical trials:

(show all 35)
idNameStatusNCT IDPhase
1PRIDE: Preventing Respiratory Illnesses During Childhood StudyCompletedNCT00927264Phase 4
2Influence of Pacifiers on Breastfeeding DurationCompletedNCT00306956Phase 3
3Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia TrialSuspendedNCT00293735Phase 2, Phase 3
4Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority SmokersCompletedNCT00341432Phase 2
5Treatment Targets for Chronic Hypertension in PregnancyRecruitingNCT00194974Phase 1, Phase 2
6Is Home Positioning Time Associated With Torticollis Rate of Recovery?CompletedNCT00347334Phase 1
7Incidence and Severity of Cardiorespiratory Events in Infants at Increased Epidemiological Risk for Sudden Infant Death Syndrome (SIDS)CompletedNCT00004392
8Factors Influencing the Racial Disparity in Sudden Infant Death Syndrome (SIDS)CompletedNCT01361893
9Reduce African-American Infant MortalityCompletedNCT01361880
10Magnetic Resonance Imaging Autopsy StudyCompletedNCT01417962
11Study of the Impact of Parental Note Taking on the Effectiveness of Anticipatory GuidanceCompletedNCT01014169
12Impact of Smoke-free Legislation on Early-life Mortality and Low Birth Weight in EnglandCompletedNCT02039583
13Parental Knowledge and Beliefs About Infant Sleep PositionCompletedNCT00005567
14Assessing the Impact of Smoke-free Legislation on Perinatal Health in the NetherlandsCompletedNCT02189265
15Re-enforcing Safe Sleep Practices for Caregivers With Tangible IncentivesCompletedNCT02010450
16Characterization of Sweat Gland Function in Patients With Recessively Inherited Hypohidrotic Ectodermal DysplasiaCompletedNCT01109290
17Reducing Environmental Tobacco Smoke in Neonatal Intensive Care Unit (NICU) Infants' HomesCompletedNCT00670280
18Secondhand Smoke Exposure Reduction Among Young Children in ChinaCompletedNCT00995254
19Varenicline Pregnancy Cohort StudyCompletedNCT01290445
20"Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits"CompletedNCT01859065
21Training Mothers of Infants in Infant Cardiopulmonary Resuscitation (CPR)CompletedNCT00570869
22Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden DeathCompletedNCT00004805
23Cardiac Autonomic Control in Children of HIV Positive MothersCompletedNCT00005353
24Do Pacifiers Protect From Sudden Infant Death Syndrome (SIDS) Through an Increase in Upper Airway Patency?RecruitingNCT01120938
25The Paediatric Virtual Autopsy TrialRecruitingNCT01888380
26Pilot Study of Novel Postpartum Educational Video InterventionRecruitingNCT02267265
27Validation of a Non Invasive Blood Marker of SIDS and Vagal DisordersRecruitingNCT01358461
28Brainstem and PrematurityRecruitingNCT02669056
29Baby NAP SACC Intervention StudyRecruitingNCT01890681
30Effect of Antenatal SSRI Exposure on the QT Interval of NeonatesRecruitingNCT02492347
31Effects of Mother Position in Skin-to-skin Contact Newborn on Oxygen Saturation Levels.RecruitingNCT02585492
32Comparing Children's Book to Brochures for Safe Sleep Education in a Home Visiting ProgramEnrolling by invitationNCT02376673
33Optimizing Technology-Delivered Interventions for Smoking in Pregnancy: The Mommy Check-Up Study.Not yet recruitingNCT02340624
34Diagnostic Performance Comparison Between Procalcitonin-based vs. ANAES-based GuidelinesNot yet recruitingNCT02590198
35Changes in Sleep Patterns and Stress in Infants Entering Child CareSuspendedNCT01265277

Search NIH Clinical Center for Sudden Infant Death Syndrome


Cochrane evidence based reviews: sudden infant death

Genetic Tests for Sudden Infant Death Syndrome

About this section

Genetic tests related to Sudden Infant Death Syndrome:

id Genetic test Affiliating Genes
1 Sudden Infant Death Syndrome25

Anatomical Context for Sudden Infant Death Syndrome

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MalaCards organs/tissues related to Sudden Infant Death Syndrome:

34
Brain, Skin, Heart, Lung, Breast, Testes, Liver

Animal Models for Sudden Infant Death Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Sudden Infant Death Syndrome:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.9ACADM, ADCYAP1, CAV3, EN1, KCNH2, KCNQ1
2MP:00053859.4ACADM, CAV3, EN1, KCNH2, KCNJ8, KCNQ1
3MP:00036319.2ADCYAP1, EN1, FEV, IDS, KCNQ1, PHOX2B
4MP:00053769.2ACADM, ADCYAP1, CAV3, EN1, FEV, KCNH2
5MP:00053868.9ADCYAP1, EN1, FEV, IDS, KCNQ1, PHOX2B

Publications for Sudden Infant Death Syndrome

About this section

Articles related to Sudden Infant Death Syndrome:

(show top 50)    (show all 642)
idTitleAuthorsYear
1
Swaddling and the Risk of Sudden Infant Death Syndrome: A Meta-analysis. (27244847)
2016
2
Perinatal Fluoxetine Exposure Impairs the CO2 Chemoreflex: Implications for Sudden Infant Death Syndrome. (27018763)
2016
3
The Disappearance of Sudden Infant Death Syndrome. (27571448)
2016
4
Impaired orexin receptor expression in the KAPlliker-Fuse nucleus in sudden infant death syndrome: possible involvement of this nucleus in arousal pathophysiology. (27353953)
2016
5
Laryngeal inflammation in the sudden infant death syndrome. (25594528)
2014
6
Sudden Infant Death Syndrome (SIDS) risk reduction and infant sleep location - moving the discussion forward. (22571891)
2013
7
Functional single-nucleotide variant of HSPD1 in sudden infant death syndrome. (23823174)
2013
8
Sudden infant death syndrome: cry characteristics. (23759336)
2013
9
A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome. (22977222)
2013
10
Maternal alcohol use and sudden infant death syndrome and infant mortality excluding SIDS. (23439895)
2013
11
Hypophosphatemia and sudden infant death syndrome (SIDS)-is ATP the link? (24151935)
2013
12
Postmortem review and genetic analysis in sudden infant death syndrome: an 11-year review. (23623143)
2013
13
A re-audit of the use of definitions of sudden infant death syndrome (SIDS) in peer-reviewed literature. (23084308)
2012
14
Review finds that bed sharing increases risk of sudden infant death syndrome. (22561148)
2012
15
Reanalyses of case-control studies examining the temporal association between sudden infant death syndrome and vaccination. (22289512)
2012
16
Cardiac ion channelopathies and the sudden infant death syndrome. (23304551)
2012
17
Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: amelioration by vitamin C. (21320590)
2011
18
Assessing knowledge of Sudden Infant Death Syndrome among African American women in two Mississippi communities. (22073527)
2011
19
Cardiac muscarinic receptor overexpression in sudden infant death syndrome. (20209124)
2010
20
Qualitative analysis of beliefs and perceptions about sudden infant death syndrome in African-American mothers: implications for safe sleep recommendations. (20303505)
2010
21
The role of infection and inflammation in sudden infant death syndrome. (19874217)
2009
22
Sudden infant death syndrome (SIDS) in African Americans: polymorphisms in the gene encoding the stress peptide pituitary adenylate cyclase-activating polypeptide (PACAP). (19120039)
2009
23
Minimizing the risks of sudden infant death syndrome: to swaddle or not to swaddle? (19540517)
2009
24
Sudden infant death syndrome: a developmental psychobiologist's perspective. (19206137)
2009
25
Sudden infant death syndrome: the genetic segue? (18477061)
2008
26
Cribs for Kids: risk and reduction of sudden infant death syndrome and accidental suffocation. (17896680)
2007
27
Sudden infant death syndrome. (17452672)
2007
28
Educating parents about the risk factors of sudden infant death syndrome: the role of neonatal intensive care unit and well baby nursery nurses. (17505237)
2007
29
Recent research in sudden infant death syndrome. (17990653)
2007
30
Novel mechanism for sudden infant death syndrome: persistent late sodium current secondary to mutations in caveolin-3. (17275750)
2007
31
Biopathology of the dentate-olivary complex in sudden unexplained perinatal death and sudden infant death syndrome related to maternal cigarette smoking. (17535563)
2007
32
Predicting the risk of sudden infant death syndrome from obstetric characteristics. (16396879)
2006
33
Knowledge of sudden infant death syndrome prevention strategies in a multicultural, disadvantaged community. (16898882)
2006
34
Genetic investigation of the TSPYL1 gene in sudden infant death syndrome. (16418600)
2006
35
Distinguishing sudden infant death syndrome from child abuse fatalities. (16818592)
2006
36
Fatty acid oxidation disorder as a cause of sudden infant death syndrome (SIDS)--a case report. (16366103)
2005
37
Sudden infant death syndrome in two infants from families of low socioeconomic status. (16398881)
2005
38
Mortality due to sudden infant death syndrome in Northern Italy, 1990-2000: a baseline for the assessment of prevention campaigns. (15367320)
2004
39
Genes and Sudden Infant Death Syndrome. (15240865)
2004
40
Adult hemoglobin levels at birth and risk of sudden infant death syndrome. (15066877)
2004
41
Sudden infant death syndrome is not associated with the mutation of PHOX2B gene, a major causative gene of congenital central hypoventilation syndrome. (15185974)
2004
42
Transcutaneous implantation of an internal cardioverter defibrillator in a small infant with recurrent myocardial ischemia and cardiac arrest simulating sudden infant death syndrome. (14720167)
2004
43
Maternal smoking: an increasing unique risk factor for sudden infant death syndrome in Sweden. (15188973)
2004
44
Air pollution and sudden infant death syndrome. (15173546)
2004
45
Sudden infant death syndrome. (15865659)
2004
46
Serum tryptase levels in sudden infant death syndrome in forensic autopsy cases. (14687774)
2004
47
Second-trimester maternal serum levels of alpha-fetoprotein and the subsequent risk of sudden infant death syndrome. (15342806)
2004
48
Sudden infant death syndrome due to parainfluenza virus 2 associated with hemophagocytic syndrome. (15474632)
2004
49
Sudden infant death syndrome. (15366145)
2003
50
Sudden infant death syndrome, bedsharing, parental weight, and age at death. (11230594)
2001

Variations for Sudden Infant Death Syndrome

About this section

UniProtKB/Swiss-Prot genetic disease variations for Sudden Infant Death Syndrome:

68 (show all 11)
id Symbol AA change Variation ID SNP ID
1CAV3p.Val14LeuVAR_043694rs121909281
2CAV3p.Thr78MetVAR_043695rs72546668
3CAV3p.Leu79ArgVAR_043696rs121909282
4GPD1Lp.Glu83LysVAR_044044rs72552292
5GPD1Lp.Ile124ValVAR_044045rs72552293
6GPD1Lp.Arg273CysVAR_044046rs72552294
7KCNJ8p.Val346IleVAR_065879rs147316959
8SCN5Ap.Ser1333TyrVAR_036666
9SCN5Ap.Phe532CysVAR_055177
10SCN5Ap.Gly1084SerVAR_055185
11SCN5Ap.Phe1705SerVAR_055207

Clinvar genetic disease variations for Sudden Infant Death Syndrome:

5 (show all 21)
id Gene Variation Type Significance SNP ID Assembly Location
1SCN4BNM_174934.3(SCN4B): c.617C> T (p.Ser206Leu)single nucleotide variantLikely pathogenicrs140348243GRCh38Chr 11, 118137097: 118137097
2KCNQ1NM_000218.2(KCNQ1): c.1135T> C (p.Trp379Arg)single nucleotide variantPathogenicrs199472768GRCh37Chr 11, 2608806: 2608806
3KCNQ1NM_000218.2(KCNQ1): c.1750G> A (p.Gly584Ser)single nucleotide variantPathogenicrs199472811GRCh37Chr 11, 2799223: 2799223
4KCNQ1NM_000218.2(KCNQ1): c.1793A> G (p.Lys598Arg)single nucleotide variantPathogenicrs199472817GRCh37Chr 11, 2799266: 2799266
5KCNQ1NM_000218.2(KCNQ1): c.820A> G (p.Ile274Val)single nucleotide variantLikely pathogenic, Pathogenicrs199472728GRCh37Chr 11, 2594115: 2594115
6KCNH2NM_000238.3(KCNH2): c.2684C> T (p.Thr895Met)single nucleotide variantPathogenicrs199473434GRCh37Chr 7, 150645540: 150645540
7KCNH2NM_172056.2(KCNH2): c.*484+1704C> Tsingle nucleotide variantPathogenicrs141401803GRCh37Chr 7, 150644799: 150644799
8KCNH2NM_000238.3(KCNH2): c.3118A> G (p.Ser1040Gly)single nucleotide variantPathogenicrs199473024GRCh37Chr 7, 150644450: 150644450
9KCNH2NM_000238.3(KCNH2): c.3470C> T (p.Pro1157Leu)single nucleotide variantLikely pathogenicrs143167166GRCh37Chr 7, 150642463: 150642463
10KCNH2NM_000238.3(KCNH2): c.818G> A (p.Arg273Gln)single nucleotide variantPathogenicrs199472877GRCh37Chr 7, 150655245: 150655245
11KCNH2NM_000238.3(KCNH2): c.835G> A (p.Val279Met)single nucleotide variantPathogenicrs199472879GRCh37Chr 7, 150655228: 150655228
12KCNH2NM_000238.3(KCNH2): c.881G> T (p.Gly294Val)single nucleotide variantLikely pathogenicrs199473549GRCh37Chr 7, 150655182: 150655182
13SCN5ANM_000335.4(SCN5A): c.2039G> A (p.Arg680His)single nucleotide variantPathogenicrs199473142GRCh37Chr 3, 38639443: 38639443
14SCN5ANM_198056.2(SCN5A): c.2989G> A (p.Ala997Thr)single nucleotide variantLikely pathogenic, Pathogenicrs137854609GRCh37Chr 3, 38622661: 38622661
15SCN5ANM_000335.4(SCN5A): c.3247G> A (p.Gly1083Ser)single nucleotide variantPathogenicrs199473190GRCh37Chr 3, 38620965: 38620965
16SCN5ANM_000335.4(SCN5A): c.4453T> C (p.Phe1485Leu)single nucleotide variantPathogenicrs199473615GRCh37Chr 3, 38597233: 38597233
17SCN5ANM_000335.4(SCN5A): c.5111T> C (p.Phe1704Ser)single nucleotide variantPathogenicrs199473627GRCh37Chr 3, 38592749: 38592749
18SCN5ANM_000335.4(SCN5A): c.5474G> A (p.Arg1825His)single nucleotide variantPathogenicrs137854610GRCh37Chr 3, 38592386: 38592386
19MT-TL1m.3290T> Csingle nucleotide variantPathogenicrs199474665GRCh37Chr MT, 3290: 3290
20MT-ND1m.3308T> Csingle nucleotide variantPathogenicrs28358582GRCh37Chr MT, 3308: 3308
21MT-ND1m.3308T> Gsingle nucleotide variantPathogenicrs28358582GRCh37Chr MT, 3308: 3308

Expression for genes affiliated with Sudden Infant Death Syndrome

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Search GEO for disease gene expression data for Sudden Infant Death Syndrome.

GO Terms for genes affiliated with Sudden Infant Death Syndrome

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Cellular components related to Sudden Infant Death Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel complexGO:000151810.8SCN2B, SCN5A
2voltage-gated potassium channel complexGO:000807610.2KCNH2, KCNJ8, KCNQ1
3sarcolemmaGO:004238310.0CAV3, KCNJ8, SCN5A, SNTA1

Biological processes related to Sudden Infant Death Syndrome according to GeneCards Suite gene sharing:

(show all 28)
idNameGO IDScoreTop Affiliating Genes
1membrane repolarization during action potentialGO:008601110.9KCNH2, KCNQ1
2potassium ion exportGO:007143510.9KCNH2, KCNQ1
3membrane repolarization during ventricular cardiac muscle cell action potentialGO:009891510.9KCNH2, KCNQ1
4potassium ion export across plasma membraneGO:009762310.9KCNH2, KCNQ1
5positive regulation of potassium ion transmembrane transportGO:190138110.9KCNH2, KCNQ1
6membrane repolarization during cardiac muscle cell action potentialGO:008601310.8KCNH2, KCNQ1
7regulation of atrial cardiac muscle cell membrane repolarizationGO:006037210.8KCNQ1, SCN5A
8regulation of atrial cardiac muscle cell membrane depolarizationGO:006037110.8SCN2B, SCN5A
9membrane depolarization during cardiac muscle cell action potentialGO:008601210.7SCN2B, SCN5A
10cardiac muscle cell action potential involved in contractionGO:008600210.7SCN2B, SCN5A
11negative regulation of potassium ion transmembrane transportGO:190138010.7CAV3, KCNH2
12regulation of membrane repolarizationGO:006030610.7KCNH2, KCNQ1
13cardiac conductionGO:006133710.7KCNH2, KCNQ1, SCN5A
14positive regulation of sodium ion transportGO:001076510.7GPD1L, SCN5A
15brainstem developmentGO:000336010.6PHOX2B, SCN5A
16regulation of ventricular cardiac muscle cell membrane depolarizationGO:006037310.6CAV3, GPD1L, SCN5A
17regulation of sodium ion transmembrane transporter activityGO:200064910.6CAV3, GPD1L, SCN2B
18regulation of sodium ion transmembrane transportGO:190230510.6SCN5A, SNTA1
19regulation of postsynaptic membrane potentialGO:006007810.5ADCYAP1, SCN2B, SCN5A
20response to pyrethroidGO:004668410.5SCN2B, TH
21regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.5CAV3, KCNH2, KCNQ1, SCN5A, SNTA1
22ventricular cardiac muscle cell action potentialGO:008600510.4CAV3, GPD1L, KCNH2, KCNQ1, SCN5A, SNTA1
23cardiac muscle contractionGO:006004810.3KCNH2, KCNQ1, SCN2B, SCN5A
24regulation of heart contractionGO:000801610.3CAV3, KCNQ1, TH
25regulation of heart rate by cardiac conductionGO:008609110.2KCNH2, KCNQ1, SCN2B, SCN5A
26cellular response to drugGO:003569010.2KCNH2, KCNQ1, TH
27social behaviorGO:003517610.1EN1, SLC6A4, TH
28regulation of heart rateGO:000202710.0CAV3, GPD1L, SCN5A, SNTA1

Molecular functions related to Sudden Infant Death Syndrome according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarizationGO:008600810.9KCNH2, KCNQ1
2voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationGO:190228210.9KCNH2, KCNQ1
3inward rectifier potassium channel activityGO:000524210.9KCNH2, KCNJ8
4voltage-gated sodium channel activity involved in cardiac muscle cell action potentialGO:008600610.8SCN2B, SCN5A
5voltage-gated sodium channel activityGO:000524810.7SCN2B, SCN5A
6sodium channel regulator activityGO:001708010.4CAV3, GPD1L, SCN2B, SNTA1
7scaffold protein bindingGO:009711010.4KCNH2, KCNQ1, SCN5A
8nitric-oxide synthase bindingGO:005099810.1CAV3, SCN5A, SLC6A4, SNTA1
9ion channel bindingGO:004432510.1CAV3, GPD1L, KCNQ1, SCN5A, SNTA1

Sources for Sudden Infant Death Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet